lactic acid has been researched along with Crohn Disease in 9 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 normals." | 3.67 | Organic anions and the diarrhea of inflammatory bowel disease. ( Breuer, RI; Gnaedinger, A; Hauck, W; Vernia, P, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Q | 1 |
| Gao, X | 1 |
| Wu, J | 1 |
| Chen, M | 1 |
| Meng, X | 1 |
| Dunsmore, G | 1 |
| Koleva, P | 1 |
| Elloumi, Y | 1 |
| Wu, RY | 1 |
| Sutton, RT | 1 |
| Ambrosio, L | 1 |
| Hotte, N | 1 |
| Nguyen, V | 1 |
| Madsen, KL | 1 |
| Dieleman, LA | 1 |
| Chen, H | 1 |
| Huang, V | 1 |
| Elahi, S | 1 |
| Lautenschläger, C | 1 |
| Schmidt, C | 1 |
| Lehr, CM | 1 |
| Fischer, D | 1 |
| Stallmach, A | 1 |
| Foong, KS | 1 |
| Patel, R | 1 |
| Forbes, A | 1 |
| Day, RM | 1 |
| James, PD | 1 |
| Black, D | 1 |
| Kuper, A | 1 |
| Saibil, F | 1 |
| van Nuenen, MH | 1 |
| Venema, K | 1 |
| van der Woude, JC | 1 |
| Kuipers, EJ | 1 |
| Treem, WR | 1 |
| Ahsan, N | 1 |
| Shoup, M | 1 |
| Hyams, JS | 1 |
| Vernia, P | 2 |
| Gnaedinger, A | 1 |
| Hauck, W | 1 |
| Breuer, RI | 1 |
| Latella, G | 1 |
| Magliocca, FM | 1 |
| Caprilli, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-center Clinical Research About Standard Diagnosis and Treatment of Neonate Severe Digestive System Malformation[NCT02699320] | 33 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lactic acid and Crohn Disease
| Article | Year |
|---|---|
PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease.
Topics: Administration, Oral; Adult; Case-Control Studies; Chitosan; Colitis, Ulcerative; Crohn Disease; Dru | 2013 |
8 other studies available for lactic acid and Crohn Disease
| Article | Year |
|---|---|
The Correlation between Endotoxin, D-Lactate, and Diamine Oxidase with Endoscopic Activity in Inflammatory Bowel Disease.
Topics: Amine Oxidase (Copper-Containing); Biomarkers; C-Reactive Protein; Colitis, Ulcerative; Crohn Diseas | 2022 |
The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn.
Topics: Aminobutyrates; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Case-Control Studies; | 2019 |
Anti-tumor necrosis factor-alpha-loaded microspheres as a prospective novel treatment for Crohn's disease fistulae.
Topics: Antibodies, Monoclonal; Cell Line; Crohn Disease; Enzyme-Linked Immunosorbent Assay; Humans; Inflixi | 2010 |
D-lactic acidosis and ataxia in a man with Crohn disease.
Topics: Acidosis, Lactic; Anti-Inflammatory Agents; Antidiarrheals; Ataxia; Crohn Disease; Diagnosis, Differ | 2010 |
The metabolic activity of fecal microbiota from healthy individuals and patients with inflammatory bowel disease.
Topics: Adult; Ammonia; Bacteria; Colitis, Ulcerative; Colon; Crohn Disease; Fatty Acids; Fatty Acids, Volat | 2004 |
Fecal short-chain fatty acids in children with inflammatory bowel disease.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Colitis, Ulcerative; Colon; Crohn Disease; Fatty Acid | 1994 |
Organic anions and the diarrhea of inflammatory bowel disease.
Topics: Anions; Citric Acid Cycle; Colitis, Ulcerative; Crohn Disease; Diarrhea; Fatty Acids, Volatile; Fece | 1988 |
Fecal organic anions in diarrhoeal diseases.
Topics: Colitis, Ulcerative; Colonic Diseases, Functional; Colonic Neoplasms; Crohn Disease; Diarrhea; Fatty | 1987 |