lactic acid has been researched along with Critical Illness in 296 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypophosphatemia may be a useful biomarker to identify thiamine deficiency in critically ill enterally-fed patients." | 9.41 | A multicenter randomized clinical trial of pharmacological vitamin B1 administration to critically ill patients who develop hypophosphatemia during enteral nutrition (The THIAMINE 4 HYPOPHOSPHATEMIA trial). ( Ali Abdelhamid, Y; Bellomo, R; Byrne, KM; Clancy, A; Collie, JT; Deane, AM; Douglas, JS; Fetterplace, K; Finnis, ME; Fujii, T; Greaves, R; Jiang, A; Maiden, MJ; Nichol, A; Plummer, MP; Russo, G; Tascone, B; Udy, AA; Yanase, F; Young, M, 2021) |
| "L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large increase in mortality." | 9.05 | L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. ( Halperin, ML; Kamel, KS; Oh, MS, 2020) |
| "This article reviews the current body of knowledge regarding lactic acidosis in critically ill patients." | 8.78 | Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992) |
| "Lactic acidosis in the emergency department and other hospital settings is typically due to tissue hypoxia with sepsis being the most common cause." | 7.88 | Lactic Acidosis in a Critically Ill Patient: Not Always Sepsis. ( Leger, KJ; Schuh, AM; Summers, C; Uspal, NG, 2018) |
| "Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered." | 7.83 | Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study. ( Chan, KS; Tseng, KL; Weng, SF; Yang, CC, 2016) |
| "Severe lactic acidosis was frequent in AKI patients treated with RRT." | 7.80 | Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy. ( De Corte, W; De Waele, JJ; Decruyenaere, J; Dhondt, AW; Hoste, EA; Vanholder, R; Vuylsteke, S, 2014) |
| "Critically ill patients who suffer from hepatic failure have elevated plasma arginine concentrations." | 7.72 | High plasma arginine concentrations in critically ill patients suffering from hepatic failure. ( Girbes, AR; Nijveldt, RJ; Prins, HA; Siroen, MP; Teerlink, T; van der Hoven, B; van Leeuwen, PA, 2004) |
| "Dogs with critical illness had nonseptic (n = 24) or septic (n = 13) etiologies." | 5.72 | Evaluation of blood thiamine concentration in hospitalized dogs with and without critical illness. ( Brainard, BM; Dowgos, NM; Lane, SL, 2022) |
| "Hypophosphatemia may be a useful biomarker to identify thiamine deficiency in critically ill enterally-fed patients." | 5.41 | A multicenter randomized clinical trial of pharmacological vitamin B1 administration to critically ill patients who develop hypophosphatemia during enteral nutrition (The THIAMINE 4 HYPOPHOSPHATEMIA trial). ( Ali Abdelhamid, Y; Bellomo, R; Byrne, KM; Clancy, A; Collie, JT; Deane, AM; Douglas, JS; Fetterplace, K; Finnis, ME; Fujii, T; Greaves, R; Jiang, A; Maiden, MJ; Nichol, A; Plummer, MP; Russo, G; Tascone, B; Udy, AA; Yanase, F; Young, M, 2021) |
| " Independent covariates related to significant decreases of linezolid concentrations included higher weight, creatinine clearance rates, and fibrinogen and antithrombin concentrations, lower concentrations of lactate, and the presence of acute respiratory distress syndrome (ARDS)." | 5.22 | Predictors of Inadequate Linezolid Concentrations after Standard Dosing in Critically Ill Patients. ( Frechen, S; Frey, L; Fuhr, U; Holdt, LM; Maier, B; Scharf, C; Taubert, M; Vogeser, M; Zander, J; Zoller, M, 2016) |
| "L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large increase in mortality." | 5.05 | L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. ( Halperin, ML; Kamel, KS; Oh, MS, 2020) |
| "This article reviews the current body of knowledge regarding lactic acidosis in critically ill patients." | 4.78 | Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992) |
| " As S-adenosylhomocysteine (SAH) was shown to reflect tissue hypoxia, we compared the ability of SAH versus lactate to predict the progression of inflammatory and septic disease to septic organ dysfunction and death." | 4.31 | S-Adenosylhomocysteine Is a Useful Metabolic Factor in the Early Prediction of Septic Disease Progression and Death in Critically Ill Patients: A Prospective Cohort Study. ( Brohm, K; Centner, FS; Fuderer, T; Hahn, B; Jäger, E; Krebs, J; Lindner, HA; Mindt, S; Neumaier, M; Schneider-Lindner, V; Schoettler, JJ; Thiel, M, 2023) |
| "Lactic acidosis in the emergency department and other hospital settings is typically due to tissue hypoxia with sepsis being the most common cause." | 3.88 | Lactic Acidosis in a Critically Ill Patient: Not Always Sepsis. ( Leger, KJ; Schuh, AM; Summers, C; Uspal, NG, 2018) |
| "Ischemic stroke is not uncommon in subjects receiving ECMO support with independent risk factor being a pre-ECMO lactic acid greater than 10 mmol/L." | 3.83 | Incidence and predictors of ischemic cerebrovascular stroke among patients on extracorporeal membrane oxygenation support. ( Camporesi, EM; Enten, G; Mangar, D; Mirsaeidi, M; Omar, HR; Shumac, J, 2016) |
| "Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered." | 3.83 | Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study. ( Chan, KS; Tseng, KL; Weng, SF; Yang, CC, 2016) |
| "Severe lactic acidosis was frequent in AKI patients treated with RRT." | 3.80 | Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy. ( De Corte, W; De Waele, JJ; Decruyenaere, J; Dhondt, AW; Hoste, EA; Vanholder, R; Vuylsteke, S, 2014) |
| " Lactic acidosis and acidaemia are associated with increased ICU mortality caused by severe underlying organ dysfunction." | 3.74 | Acid-base disturbances in critically ill patients with cirrhosis. ( Doberer, D; Funk, GC; Holzinger, U; Kneidinger, N; Lindner, G; Schneeweiss, B, 2007) |
| " Critically ill patients were selected on the clinical suspicion of the presence of lactic acidosis." | 3.73 | Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients. ( Gunnerson, KJ; He, S; Kellum, JA; Saul, M, 2006) |
| "Critically ill patients who suffer from hepatic failure have elevated plasma arginine concentrations." | 3.72 | High plasma arginine concentrations in critically ill patients suffering from hepatic failure. ( Girbes, AR; Nijveldt, RJ; Prins, HA; Siroen, MP; Teerlink, T; van der Hoven, B; van Leeuwen, PA, 2004) |
| "Patients with tissue perfusion deficit usually have lactic acidosis or hyperlactacidemia and blood lactate level has been used to diagnose this condition and to monitor the disease progression." | 3.70 | Blood lactate determined by a portable device in critically ill patients. ( Neungton, N; Permpikul, C; Ratanarat, R, 2000) |
| "New-onset acute kidney injury was observed in 10 patients (6." | 3.30 | Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial. ( Gibbons, KS; Kennedy, M; Le Marsney, R; Mattke, A; Raman, S; Schibler, A; Schlapbach, LJ; Trnka, P, 2023) |
| "Fifty-eight patients with severe sepsis were randomly assigned to receive either magnesium (n = 30) or placebo (n = 28)." | 2.94 | Effect of magnesium supplementation on lactate clearance in critically ill patients with severe sepsis: a randomized clinical trial. ( Abdollahi, A; Khalili, H; Mohammadi, M; Noormandi, A, 2020) |
| "In patients with cardiogenic pulmonary edema, the sonography group had a significantly shorter ICU stay and a faster return to normal myocardial injury marker levels and perfusion parameters than the control group (P < ." | 2.79 | Integrated cardiopulmonary sonography: a useful tool for assessment of acute pulmonary edema in the intensive care unit. ( Chai, WZ; Liu, DW; Wang, XT; Zhang, HM, 2014) |
| "Resuscitation is the process of treating shock in an attempt to restore normal physiology." | 2.52 | Endpoints in resuscitation. ( Connelly, CR; Schreiber, MA, 2015) |
| "Sepsis and multiple organ failure are characterized by an excessive release of inflammatory mediators and a marked stimulation of stress hormones." | 2.44 | Substrate utilization in sepsis and multiple organ failure. ( Chioléro, R; Tappy, L, 2007) |
| "LAR measured early in the course of critical illness is significantly associated with mortality and development of MODS when compared with initial lactate or initial albumin alone in critically ill pediatric patients." | 1.91 | The Association of the Lactate-Albumin Ratio With Mortality and Multiple Organ Dysfunction in PICU Patients. ( Gai, J; Patel, AK; Pollack, MM; Ray, CC, 2023) |
| "Hyperlactatemia is associated with mortality outcomes in patients undergoing CRRT for acute kidney injury." | 1.91 | Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury. ( Han, SS; Joo, KW; Kang, MW; Kim, DK; Kim, SG; Kim, YC; Kim, YS; Lee, J; Oh, KH; Yun, D, 2023) |
| "VTE risk and blood hyperlactatemia have been associated with a higher mortality risk in critically ill Covid-19 patients who are hospitalized in the ICU in Saudi Arabia." | 1.91 | The risk of venous thromboembolism and blood hyperlactatemia is associated with increased mortality among critically ill patients with Covid-19. ( Ali Khan, I; AlQarni, HM; Alshammary, AF; Farzan, R; Vennu, V, 2023) |
| "Dogs with critical illness had nonseptic (n = 24) or septic (n = 13) etiologies." | 1.72 | Evaluation of blood thiamine concentration in hospitalized dogs with and without critical illness. ( Brainard, BM; Dowgos, NM; Lane, SL, 2022) |
| "Hyperlactatemia is a common complication in critically ill patients with high morbidity and mortality." | 1.72 | Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study. ( Bai, M; Li, L; Sun, S; Zhang, Q, 2022) |
| "No single laboratory value can diagnose necrotizing fasciitis; ultimately, necrotizing fasciitis is a clinical diagnosis and therefore presents a diagnostic dilemma for many physicians." | 1.72 | Finger Test for the Diagnosis of a Critically Ill Patient with Necrotizing Fasciitis. ( Farrell, R; Jeong, J; Livshits, D; Sokup, B, 2022) |
| "All 82 patients with diabetic ketoacidosis survived." | 1.51 | Acute Kidney Injury in Critically Ill Children Admitted to the PICU for Diabetic Ketoacidosis. A Retrospective Study. ( Gendler, Y; Kadmon, G; Kaplan, E; Nahum, E; Weissbach, A; Zur, N, 2019) |
| "Our primary outcome was critical illness, defined as one or more of the composite outcomes of death, vasopressor use or intensive care unit (ICU) admission within 72 hours of presentation." | 1.48 | Comparison of qSOFA with current emergency department tools for screening of patients with sepsis for critical illness. ( Baumann, BM; Darger, B; Fernandez, D; Greenwood, JC; Jung, SY; Kilgannon, JH; Nuckton, TJ; Rodriguez, RM; Shofer, FS; Speich, KG; Troeger, D; Valencia, J, 2018) |
| "Although hyperlactatemia is often developed in critically ill patients, it is unclear whether hyperlactatemia is associated with poor prognosis for surgical ICU (SICU) patients." | 1.48 | The incidence and outcome of hyperlactatemia in patients admitted to the intensive care unit after elective surgery. ( Abe, T; Sasabuchi, Y; Takinami, M; Uchino, S, 2018) |
| "Systemic inflammatory response syndrome was also recorded." | 1.48 | Predictive Validity of Sepsis-3 Definitions and Sepsis Outcomes in Critically Ill Patients: A Cohort Study in 49 ICUs in Argentina. ( Díaz, A; Dubin, A; Estenssoro, E; Kanoore Edul, VS; Klein, F; Lattanzio, B; Loudet, CI; Osatnik, J; Pálizas, F; Piezny, D; Pozo, MO; Ríos, FG; Rubatto Birri, PN; Santamaría, A; Tuhay, G; Vázquez, DN; Zakalik, G, 2018) |
| "Hyperlactatemia was defined as a blood lactate concentration ≥5mmol/L and high-grade hyperlactatemia a lactate level ≥10mmol/L." | 1.46 | Hyperlactatemia in ICU patients: Incidence, causes and associated mortality. ( Ayestarán, I; Ferreruela, M; Llompart-Pou, JA; Raurich, JM, 2017) |
| "Persistent hyperlactatemia is associated with adverse outcome in critically ill patients." | 1.46 | Hyperlactatemia and the Importance of Repeated Lactate Measurements in Critically Ill Patients. ( Godinjak, A; Iglica, A; Jusufovic, S; Kukuljac, A; Rama, A; Rozajac, S; Tancica, I; Zvizdic, F, 2017) |
| "We demonstrated that NMES chronaxie-based protocol is safe and feasible." | 1.46 | Safety and feasibility of a neuromuscular electrical stimulation chronaxie-based protocol in critical ill patients: A prospective observational study. ( Babault, N; Carvalho, VO; de Oliveira, TP; Durigan, JLQ; Lemos, BL; Mazullo, JB; Silva, PE, 2017) |
| "Hyperlactatemia was associated with death in the ICU [odds ratio 1." | 1.43 | Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients. ( Fuhrmann, V; Haas, SA; Kluge, S; Lange, T; Metschke, M; Petzoldt, M; Saugel, B, 2016) |
| "In this prospective study, 48 septic shock children seen in Shanghai Children's Hospital, Shanghai Jiao Tong University were enrolled from Jun 2012 to May 2014." | 1.40 | [Central venous-to-arterial carbon dioxide difference in critically ill pediatric patients with septic shock]. ( Chen, R; Cui, Y; Miao, H; Rong, Q; Xu, L; Zhang, Y, 2014) |
| " The concentrations of plasma lactate in pre-(A), post-dialyzer (V) sites and ultrafiltrate were measured after each dosage of CVVH was carried out for 30 minutes." | 1.40 | Effects of different doses in continuous veno-venous hemofiltration on plasma lactate in critically ill patients. ( Chen, J; Chen, M; Guan, X; Huang, S; Li, L; Liu, Y; Liu, Z; Ma, J; Ouyang, B; Wu, J, 2014) |
| " Adverse events included rising serum lactate (30." | 1.39 | Tolerability and safety of enteral nutrition in critically ill patients receiving intravenous vasopressor therapy. ( Mancl, EE; Muzevich, KM, 2013) |
| " Catecholamine dosage was significantly reduced after ECMO implantation." | 1.39 | Single-center experience with extracorporeal life support in 103 nonpostcardiotomy patients. ( Arlt, M; Camboni, D; Hilker, M; Keyser, A; Lubnow, M; Lunz, D; Philipp, A; Rupprecht, L; Schmid, C; Schopka, S; Zacher, R; Zimmermann, M, 2013) |
| "We enrolled 105 patients with septic shock hospitalized in the mixed intensive care unit of a tertiary hospital." | 1.39 | Elevated adipose tissue lactate to pyruvate (L/P) ratio predicts poor outcome in critically ill patients with septic shock: a microdialysis study. ( Armaganidis, A; Dimopoulou, I; Ilias, I; Kopterides, P; Nikitas, N; Theodorakopoulou, M; Vassiliadi, DA, 2013) |
| "The pediatric critical illness scores were different among the three groups (χ2 = 12." | 1.38 | [Relationship between blood lactate level and disease severity in critically ill children]. ( Fan, JH; Huang, W; Xu, ZY; Zhou, X, 2012) |
| "Lactic acid was first discovered in human blood in 1843." | 1.37 | Lactate in the critically ill patients: an outcome marker with the times. ( Nguyen, HB, 2011) |
| "In patients with infections, increasing serum lactate values of >or=2." | 1.36 | Emergency department lactate is associated with mortality in older adults admitted with and without infections. ( del Portal, DA; Dorsey, PJ; Gaieski, DF; Goyal, M; Mikkelsen, ME; Pines, JM; Shofer, F; Synnestvedt, M; Weiner, MG, 2010) |
| "This group of patients is those with severe sepsis and septic shock and they could also benefit greatly from timely prehospital care." | 1.35 | Sepsis: a need for prehospital intervention? ( Daniels, R; Nutbeam, T; Robson, W, 2009) |
| "Shock was more frequently present in the low [BE] group (46% versus 24%, P = 0." | 1.35 | Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches. ( Dubin, A; Kutscherauer, DO; Masevicius, FD; Pein, MC; Tuhay, G, 2008) |
| "Critically ill patients treated for multiple organ failure often develop muscle dysfunction." | 1.33 | Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure. ( Fredriksson, K; Hammarqvist, F; Hultenby, K; Ljungqvist, O; Rooyackers, O; Strigård, K; Wernerman, J, 2006) |
| "CVVH corrects metabolic acidosis in acute renal failure patients through its effect on unmeasured anions, phosphate and chloride." | 1.32 | Impact of continuous veno-venous hemofiltration on acid-base balance. ( Bellomo, R; Morimatsu, H; Rocktäschel, J; Ronco, C; Uchino, S, 2003) |
| "Fifty-six patients with severe sepsis and blood lactate concentration <3 mmol/L." | 1.32 | Low exogenous lactate clearance as an early predictor of mortality in normolactatemic critically ill septic patients. ( Ciebiera, JP; Grimaud, D; Ichai, C; Levraut, J; Perus, O; Petit, I, 2003) |
| "Twenty-one patients had severe sepsis or septic shock." | 1.32 | Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients. ( Bankov, A; Marik, PE, 2003) |
| "Stress hyperglycemia is frequent in critically ill patients." | 1.32 | Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness. ( Coopmans, W; Giulietti, AP; Mathieu, C; Michalaki, M; Van den Berghe, G; Van Herck, E; Weekers, F, 2003) |
| "Eighty patients with multiple trauma were studied (514 samples) during their intensive care unit courses (Injury Severity Score 27." | 1.31 | Metabolic correlates of oxygen debt predict posttrauma early acute respiratory distress syndrome and the related cytokine response. ( Rixen, D; Siegel, JH, 2000) |
| "The incidence of disseminated intravascular coagulation (DIC) was significantly higher in the nonsurvivors than in the survivors." | 1.31 | Serial measurement of arterial lactate concentrations as a prognostic indicator in relation to the incidence of disseminated intravascular coagulation in patients with systemic inflammatory response syndrome. ( Gando, S; Kemmotsu, O; Kobayashi, S; Morimoto, Y; Nanzaki, S, 2001) |
| "Ten critically ill patients with acute renal failure and stable blood lactate concentrations." | 1.30 | Effect of continuous venovenous hemofiltration with dialysis on lactate clearance in critically ill patients. ( Ciebiera, JP; Grimaud, D; Ichai, C; Jambou, P; Labib, Y; Levraut, J, 1997) |
| "In continuous treatment of acute renal failure, hemofiltrate is always available, but it contains only low protein concentrations and after the filtration process, metabolism is rapidly stopped." | 1.30 | Which organic acids does hemofiltrate contain in the presence of acute renal failure? ( Guth, HJ; Jäger, B; Kraatz, G; Panzig, E; Rudolph, PE; Zschiesche, M, 1999) |
| "In hyperglycemic patients with multiple trauma, hepatic glucose production and gluconeogenesis are increased, suggesting that autoregulation of hepatic glucose production may be defective." | 1.29 | Effects of lactate on glucose metabolism in healthy subjects and in severely injured hyperglycemic patients. ( Cayeux, MC; Chioléro, R; Jéquier, E; Schindler, C; Schneiter, P; Tappy, L; Temler, E, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 37 (12.50) | 18.2507 |
| 2000's | 48 (16.22) | 29.6817 |
| 2010's | 141 (47.64) | 24.3611 |
| 2020's | 70 (23.65) | 2.80 |
| Authors | Studies |
|---|---|
| Sauer, CM | 1 |
| Gómez, J | 1 |
| Botella, MR | 1 |
| Ziehr, DR | 1 |
| Oldham, WM | 1 |
| Gavidia, G | 1 |
| Rodríguez, A | 1 |
| Elbers, P | 1 |
| Girbes, A | 1 |
| Bodi, M | 1 |
| Celi, LA | 2 |
| Sheng, Y | 1 |
| Zheng, WL | 1 |
| Shi, QF | 1 |
| Zhang, BY | 1 |
| Yang, GY | 1 |
| Dudoignon, E | 1 |
| Quennesson, T | 1 |
| De Tymowski, C | 2 |
| Moreno, N | 1 |
| Coutrot, M | 1 |
| Chaussard, M | 1 |
| Guillemet, L | 1 |
| Abid, S | 1 |
| Fratani, A | 1 |
| Ressaire, Q | 1 |
| Cupaciu, A | 1 |
| Weinmann, V | 1 |
| Pharaboz, A | 1 |
| Benyamina, M | 1 |
| Mebazaa, A | 1 |
| Legrand, M | 2 |
| Depret, F | 2 |
| Deniau, B | 1 |
| Erdoğan, M | 1 |
| Findikli, HA | 1 |
| Chen, XF | 1 |
| Mc Dermott, S | 1 |
| Dargan, C | 1 |
| Gonzalez Dominguez, E | 1 |
| Music Aplenc, L | 1 |
| Flatt, T | 1 |
| Iqbal, N | 1 |
| Sai, IN | 1 |
| Prasad, R | 1 |
| T, V | 1 |
| Maiwall, R | 1 |
| Kumar, A | 3 |
| Pasupuleti, SSR | 1 |
| Hidam, AK | 1 |
| Tevethia, H | 1 |
| Kumar, G | 1 |
| Sahney, A | 1 |
| Mitra, LG | 1 |
| Sarin, SK | 1 |
| Li, X | 1 |
| Gong, M | 1 |
| Fu, S | 1 |
| Zhang, J | 3 |
| Wu, S | 1 |
| Livshits, D | 1 |
| Sokup, B | 1 |
| Farrell, R | 1 |
| Jeong, J | 1 |
| Lane, SL | 1 |
| Dowgos, NM | 1 |
| Brainard, BM | 1 |
| Li, L | 3 |
| Bai, M | 1 |
| Zhang, Q | 3 |
| Sun, S | 1 |
| Nygaard, U | 1 |
| Dungu, KHS | 1 |
| von Linstow, ML | 1 |
| Lundstrøm, K | 1 |
| Zhang, H | 2 |
| Vissing, NH | 1 |
| Lu, T | 1 |
| Tan, L | 1 |
| Xu, K | 1 |
| Liu, J | 2 |
| Liu, C | 1 |
| Zhang, G | 1 |
| Shi, R | 1 |
| Huang, Z | 1 |
| Song, J | 3 |
| Yu, T | 3 |
| Yan, Q | 3 |
| Wu, L | 3 |
| Li, S | 3 |
| Wang, L | 5 |
| Tamakawa, T | 4 |
| Endoh, H | 4 |
| Kamimura, N | 4 |
| Deuchi, K | 3 |
| Nishiyama, K | 3 |
| Rocha, AC | 2 |
| Chagas, JB | 2 |
| Andrade, JV | 2 |
| Pinto, C | 2 |
| Oliveira, G | 2 |
| Dias, AS | 2 |
| Carvalho, L | 2 |
| Raman, S | 1 |
| Gibbons, KS | 1 |
| Mattke, A | 1 |
| Schibler, A | 1 |
| Trnka, P | 1 |
| Kennedy, M | 1 |
| Le Marsney, R | 1 |
| Schlapbach, LJ | 1 |
| Wang, G | 1 |
| Xu, R | 1 |
| Fu, Y | 1 |
| Liu, X | 2 |
| Zhang, Y | 3 |
| Wang, J | 3 |
| Yu, BZ | 1 |
| Chen, ML | 1 |
| Cao, YD | 1 |
| Wei, B | 1 |
| Wang, JY | 1 |
| Kim, SG | 1 |
| Lee, J | 1 |
| Yun, D | 1 |
| Kang, MW | 1 |
| Kim, YC | 1 |
| Kim, DK | 1 |
| Oh, KH | 1 |
| Joo, KW | 1 |
| Kim, YS | 1 |
| Han, SS | 1 |
| Li, H | 2 |
| Chen, J | 3 |
| Xing, X | 1 |
| Lou, D | 1 |
| Alshammary, AF | 1 |
| AlQarni, HM | 1 |
| Farzan, R | 1 |
| Ali Khan, I | 1 |
| Vennu, V | 1 |
| Ray, CC | 1 |
| Pollack, MM | 1 |
| Gai, J | 1 |
| Patel, AK | 1 |
| Chen, W | 1 |
| Chen, M | 3 |
| Qiao, X | 1 |
| Jerman, A | 1 |
| Gubenšek, J | 1 |
| Berden, J | 1 |
| Peršič, V | 1 |
| Centner, FS | 1 |
| Schoettler, JJ | 1 |
| Brohm, K | 1 |
| Mindt, S | 1 |
| Jäger, E | 1 |
| Hahn, B | 1 |
| Fuderer, T | 1 |
| Lindner, HA | 1 |
| Schneider-Lindner, V | 1 |
| Krebs, J | 1 |
| Neumaier, M | 1 |
| Thiel, M | 1 |
| Hassoun, Y | 1 |
| Konan, A | 1 |
| Simon, G | 1 |
| Verdot, P | 1 |
| Lakkis, Z | 1 |
| Loffroy, R | 1 |
| Besch, G | 1 |
| Piton, G | 1 |
| Delabrousse, E | 1 |
| Calame, P | 1 |
| Zhi, HJ | 1 |
| Cui, J | 1 |
| Yuan, MW | 1 |
| Zhao, YN | 1 |
| Zhao, XW | 1 |
| Zhu, TT | 1 |
| Jia, CM | 1 |
| Li, Y | 4 |
| Ren, J | 1 |
| Kang, Q | 1 |
| Wang, F | 1 |
| Yu, W | 1 |
| Guo, T | 1 |
| Zheng, R | 1 |
| Yi, H | 1 |
| Yang, Y | 1 |
| Oh, TK | 1 |
| Song, IA | 1 |
| Bae, HJ | 1 |
| Jeon, YT | 1 |
| Hargreaves, DS | 1 |
| de Carvalho, JLJ | 1 |
| Smith, L | 1 |
| Picton, G | 1 |
| Venn, R | 1 |
| Hodgson, LE | 1 |
| García de Guadiana-Romualdo, L | 1 |
| Albaladejo-Otón, MD | 1 |
| Berger, M | 1 |
| Jiménez-Santos, E | 1 |
| Jiménez-Sánchez, R | 1 |
| Esteban-Torrella, P | 1 |
| Rebollo-Acebes, S | 1 |
| Hernando-Holgado, A | 1 |
| Ortín-Freire, A | 1 |
| Trujillo-Santos, J | 1 |
| Cazzolli, DM | 1 |
| Prittie, JE | 1 |
| Fox, PR | 1 |
| Lamb, K | 1 |
| Kamel, KS | 1 |
| Oh, MS | 1 |
| Halperin, ML | 1 |
| Noormandi, A | 1 |
| Khalili, H | 1 |
| Mohammadi, M | 1 |
| Abdollahi, A | 1 |
| Chen, X | 1 |
| Bi, J | 1 |
| Du, Z | 1 |
| Ren, Y | 1 |
| Wei, S | 1 |
| Ren, F | 1 |
| Wu, Z | 1 |
| Lv, Y | 1 |
| Wu, R | 1 |
| Hayashi, Y | 1 |
| Nitta, M | 1 |
| Kern-Goldberger, AR | 1 |
| Polin, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Colloid (20% Albumin) Versus Crystalloid (Plasmalyte) for Fluid Resuscitation in Cirrhotics With Sepsis Induced Hypotension.[NCT02721238] | 100 participants (Actual) | Interventional | 2016-12-01 | Completed | |||
| Role of Blood Lactate Level in Prediction of Outcome of Cirrhotic Patients at The Intensive Care Unit[NCT06121908] | 50 participants (Anticipated) | Observational | 2023-11-15 | Not yet recruiting | |||
| DPP3, Angiotensin II, and Renin Kinetics in Sepsis (DARK-Sepsis) Pilot: Serum Biomarkers to Predict Response to Angiotensin II vs. Standard-of-care Vasopressor Therapy in the Treatment of Septic Shock, a Randomized Controlled Pilot Trial[NCT05824767] | Phase 4 | 40 participants (Anticipated) | Interventional | 2023-04-17 | Recruiting | ||
| Effect of Personalized Hemodynamic Management Based on Serum Renin Concentration on Acute Kidney Injury Progression in Patients With Shock: a Randomized Controlled Trial.[NCT05898126] | 800 participants (Anticipated) | Interventional | 2023-06-05 | Not yet recruiting | |||
| Fluids in Sepsis and Septic Shock: A Pilot Randomized Controlled Trial[NCT02748382] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2016-08-18 | Completed | ||
| Observation of the Prevalence of Sublingual Microcirculatory Alterations With SDF Imaging in Intensive Care Patients[NCT01179243] | 500 participants (Actual) | Observational | 2011-09-30 | Completed | |||
| Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients: Pathophysiological Determinants, and Relation to Changes in Systemic, Regional and Microcirculatory Blood Flow[NCT04693923] | 42 participants (Anticipated) | Interventional | 2021-02-01 | Not yet recruiting | |||
| The Thiamine Administration After Cardiac Surgery Trial[NCT04641104] | Phase 4 | 200 participants (Actual) | Interventional | 2020-11-20 | Completed | ||
| Impact of Thiamine Supplementation on Mortality in Septic Shock. A Controlled Before-and-after Study.[NCT05840718] | 80 participants (Anticipated) | Observational | 2023-09-30 | Not yet recruiting | |||
| Renin as a Biomarker of Haemodynamic Normalisation: Associations With Outcomes After Cardiac Surgery[NCT04303455] | 104 participants (Actual) | Observational | 2020-03-24 | Completed | |||
| Agreement Between Capillary and Venous Lactate in Emergency Department Patients[NCT02694887] | 240 participants (Actual) | Observational | 2016-03-31 | Completed | |||
| REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study): a Substudy Protocol for a Randomised Clinical Trial[NCT05029167] | 300 participants (Anticipated) | Interventional | 2017-09-11 | Recruiting | |||
| Dexamethasone for Cardiac Surgery Trial[NCT00293592] | 4,500 participants (Actual) | Interventional | 2006-05-31 | Completed | |||
| Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965] | 350 participants (Anticipated) | Observational | 2018-08-15 | Active, not recruiting | |||
| Role of Lactate Level in Prediction of Patients'Acute Gastrointestinal Bleeding Admissions to Intensive Care Unit, Interventions and Short Term Outcomes[NCT04104425] | 300 participants (Actual) | Observational | 2020-01-15 | Completed | |||
| Drug Monitoring of Antibiotics in Critical Care Patients[NCT01793012] | 186 participants (Actual) | Observational | 2013-03-31 | Completed | |||
| Physiological Effects of Lactate in Individuals With Chronic Heart Failure[NCT06121323] | 12 participants (Anticipated) | Interventional | 2023-11-22 | Not yet recruiting | |||
| Prediction of Arterial Lactate and Blood Gas Values Through the Analysis of Central Venous Blood. A Human, Prospective, Multicenter Validation Study.[NCT04538339] | 398 participants (Actual) | Observational | 2020-09-10 | Completed | |||
| Early Lactate-Directed Therapy on the ICU: A Randomized Controlled Trial[NCT00270673] | Phase 3 | 350 participants (Anticipated) | Interventional | 2006-02-28 | Completed | ||
| Resuscitation Failure, Protein Carbonyl and Receptor Interacting Protein Kinase 3 as Mortality Predictor in Septic Patient[NCT04169412] | 72 participants (Actual) | Observational [Patient Registry] | 2019-02-22 | Completed | |||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| Early Goal Directed Therapy Using a Physiological Holistic View. A Multicenter Study in Latin America: The ANDROMEDA-SHOCK Study[NCT03078712] | 424 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| To Compare the Effectiveness of Various Methods of Estimating Volume Resuscitation in Patients With Cirrhosis With Sepsis Induced Hypotension[NCT05059795] | 75 participants (Anticipated) | Observational | 2020-02-01 | Recruiting | |||
| Goal-directed Fluid Therapy in Elderly Patients Undergoing Lumbar Decompression Surgery in the Prone Position: A Randomized Controlled Clinical Trial[NCT03974906] | 90 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159] | Phase 2 | 140 participants (Actual) | Interventional | 2018-02-05 | Completed | ||
| Built-in Calculator Optimizes Continuous Veno-venous Hemofiltration Prescription and Improves Therapeutic Quality in Critically-ill Acute Kidney Injury Patients[NCT05638711] | 1 participants (Actual) | Observational | 2019-01-01 | Completed | |||
| A Multi-center, Multinational, Randomized, Double-blind, Controlled, Dose Comparison Study to Evaluate Safety and Efficacy of MP4OX Plus Standard Treatment, in Severely Injured Trauma Subjects With Lactic Acidosis Due to Hemorrhagic Shock[NCT01973504] | Phase 2 | 0 participants (Actual) | Interventional | 2013-12-31 | Withdrawn (stopped due to Sangart ceased operations) | ||
| Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)[NCT02742974] | 196 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| Determining the Factors That Affects Emergency Department Visits of Hyperglycemic Patients in 30 Days.[NCT04665128] | 120 participants (Anticipated) | Observational | 2020-12-15 | Recruiting | |||
| Markers of Tissue Perfusion as Predictors of Complicated Evolution in Patients With Left Ventricular Dysfunction Submitted to Coronary Artery Bypass Surgery[NCT01178866] | 87 participants (Actual) | Observational | 2006-01-31 | Completed | |||
| Using Near-infrared Spectroscopy (NIRS) Monitor to Noninvasively Evaluate Hepatic Venous Saturation[NCT01891188] | 100 participants (Anticipated) | Observational | 2013-06-30 | Active, not recruiting | |||
| Near Infrared Spectroscopy (NIRS) for Heart Failure Assessment in the Outpatient Setting[NCT01577810] | 100 participants (Anticipated) | Interventional | 2013-06-30 | Recruiting | |||
| Evaluation of Hepatic Mitochondrial Function in Sepsis[NCT00889083] | 0 participants (Actual) | Observational | 2009-04-30 | Withdrawn (stopped due to no patients to include) | |||
| Peritoneal/Serum Lactate Ratio in Relaparotomy[NCT01161849] | 60 participants (Anticipated) | Observational | 2010-08-31 | Completed | |||
| Feasibility of Microdialysis by Laparoscopy[NCT01786694] | Phase 3 | 11 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit[NCT01624519] | 50 participants (Anticipated) | Interventional | 2012-08-31 | Not yet recruiting | |||
| Protocolized Care for Early Septic Shock[NCT00510835] | 1,351 participants (Actual) | Interventional | 2008-03-31 | Completed | |||
| [NCT01824771] | 15 participants (Actual) | Observational [Patient Registry] | 2013-03-03 | Completed | |||
| Personalised Medicine With IgGAM Compared With Standard of Care for Treatment of Peritonitis After Infectious Source Control (the PEPPER Trial): a Randomised, Controlled Trial[NCT03334006] | Phase 2 | 200 participants (Anticipated) | Interventional | 2017-11-20 | Suspended (stopped due to Due to safety-relevant aspects with regard to internal processes of the sponsor) | ||
| Vasopressin Plasma Concentrations in Responders and Non-responders to Exogenous Vasopressin Infusion in Patients With Septic Shock[NCT03014063] | 18 participants (Actual) | Observational | 2016-11-30 | Completed | |||
| Use of Arginine Vasopressin in Early Postoperative Management After Fontan Palliation[NCT03088345] | Phase 2/Phase 3 | 20 participants (Actual) | Interventional | 2017-03-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Arm | 2.9 |
| Placebo Arm | 1.93 |
Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 11.5 |
| Placebo Arm | 11 |
In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 11 |
| Placebo Arm | 13 |
Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.
| Intervention | days (Mean) |
|---|---|
| Treatment Arm | 4.76 |
| Placebo Arm | 4.66 |
ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 6 |
| Placebo Arm | 10 |
PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | Percent (Mean) |
|---|---|
| Treatment Arm | 63 |
| Placebo Arm | 58 |
Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.
| Intervention | hours (Mean) |
|---|---|
| HAT Treatment | 27 |
| Comparator | 53 |
Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 22 |
| Placebo Arm | 22.4 |
The primary study outcome is hospital mortality (defined as the number of deaths prior to discharge or 60 days, whichever comes first). The secondary outcomes are duration of survival (90 day and 1 year) and clinical evidence of organ dysfunction. (NCT00510835)
Timeframe: prior to discharge or 60 days, whichever comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Early Goal Directed Therapy (EGDT) | 92 |
| Protocolized Standard Care (PSC) | 81 |
| Usual Care | 86 |
Organ perfusion pressure measured as Mean Arterial Pressure (MAP). It will be measured hourly for 24 postoperative hours for all subjects and compared between the two study groups over the whole time of observation as the main between-group effect in panel regression. (NCT03088345)
Timeframe: 24 hours post-operative
| Intervention | mmHg (Mean) |
|---|---|
| Vasopressin, Arginine | 67 |
| Placebo | 66 |
The transpulmonary pressure gradient (TPG), defined as the difference between mean pulmonary arterial pressure (Ppa) and left/common atrial (common atrial) pressure (Pla) will be measured hourly for 24 postoperative hours for all subjects and compared between the two study groups over the whole time of observation as the main between-group effect in panel regression. (NCT03088345)
Timeframe: 24 hours post-operative
| Intervention | mmHg (Mean) |
|---|---|
| Vasopressin, Arginine | 6.4 |
| Placebo | 8.3 |
The vasoactive inotrope score (VIS) is a linear sum of vasoactive and inotrope durg infusion doses. It is usually reported as dimensionless but is sometimes reported as normalized to dopamine mcg/kg/min equivalents. The score starts at 0 and has no defined upper limit, with a commonly observed range 0-50. It is used as a measure of the intensity of hemodynamic support, with higher scores indicating more vasoactive drug support for patients. The relationship of VIS to other patient outcomes is not consistent. It will be calculated hourly for all subjects and compared between groups over the entire observation timeframe. (NCT03088345)
Timeframe: 48 hours post-operative
| Intervention | units (Mean) |
|---|---|
| Vasopressin, Arginine | 11 |
| Placebo | 11.3 |
Transaminase levels (alanine and aspartate, measured in IU/L ) will be tracked for all patients and changes will be compared between study groups. (NCT03088345)
Timeframe: 48 hours post-operative
| Intervention | iU/L (Mean) |
|---|---|
| Vasopressin, Arginine | 715 |
| Placebo | 522 |
Cystatin levels will be measured at baseline (immediately before cardiopulmonary bypass) 24 hours postoperative. The change (postoperative minus baseline) in cystatin level will be compared between groups. (NCT03088345)
Timeframe: from baseline pre-cardiopulmonary bypass to 24 hours post-operative
| Intervention | mg/L (Mean) |
|---|---|
| Vasopressin, Arginine | 0.095 |
| Placebo | 0.017 |
Length of stay (LOS) measured in postoperative hours compared between groups (NCT03088345)
Timeframe: from time of operation until hospital discharge
| Intervention | hours (Mean) |
|---|---|
| Vasopressin, Arginine | 180 |
| Placebo | 203 |
26 reviews available for lactic acid and Critical Illness
| Article | Year |
|---|---|
L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis.
Topics: Acidosis, Lactic; Anions; Bicarbonates; Citric Acid Cycle; Critical Illness; Electron Transport Chai | 2020 |
Current Controversies in Caring for the Critically Ill Pulmonary Embolism Patient.
Topics: Anticoagulants; Biomarkers; Computed Tomography Angiography; Critical Illness; Echocardiography; Ele | 2020 |
Quantitative Assessment of Blood Lactate in Shock: Measure of Hypoxia or Beneficial Energy Source.
Topics: Animals; Critical Illness; Disease Models, Animal; Dogs; Humans; Hypoxia; Lactic Acid; Liver; Models | 2020 |
Evaluating the Possibility of Translating Technological Advances in Non-Invasive Continuous Lactate Monitoring into Critical Care.
Topics: Critical Care; Critical Illness; Humans; Lactic Acid; Monitoring, Physiologic; Technology | 2021 |
Blood lactate levels in sepsis: in 8 questions.
Topics: Critical Illness; Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis | 2021 |
How to assess hemodynamic status in very preterm newborns in the first week of life?
Topics: Atrial Pressure; Cardiac Output; Cerebrovascular Circulation; Critical Illness; Echocardiography; He | 2017 |
Detailing the cardiovascular profile in shock patients.
Topics: Carbon Dioxide; Critical Illness; Fluid Therapy; Hemodynamics; Humans; Lactic Acid; Microcirculation | 2017 |
Lactate clearance is a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review and meta-analysis*.
Topics: Biomarkers; Critical Illness; Intensive Care Units; Lactic Acid; Prognosis; Reproducibility of Resul | 2014 |
Blood lactate measurement and interpretation in critically ill equine adults and neonates.
Topics: Animals; Animals, Newborn; Critical Illness; Horse Diseases; Horses; Lactic Acid | 2014 |
Searching for predictors of surgical complications in critically ill surgery patients in the intensive care unit: a review.
Topics: Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Critical Illness; Forec | 2015 |
Endpoints in resuscitation.
Topics: ADAM Proteins; ADAMTS13 Protein; Biomarkers; Critical Illness; Disintegrins; Endpoint Determination; | 2015 |
The value of blood lactate kinetics in critically ill patients: a systematic review.
Topics: Critical Illness; Humans; Intensive Care Units; Lactic Acid; Sepsis | 2016 |
Anion gap as a prognostic tool for risk stratification in critically ill patients - a systematic review and meta-analysis.
Topics: Acid-Base Equilibrium; Critical Illness; Hospital Mortality; Humans; Intensive Care Units; Lactic Ac | 2016 |
Lactate: biomarker and potential therapeutic target.
Topics: Biomarkers; Critical Care; Critical Illness; Hemodynamics; Humans; Lactic Acid; Predictive Value of | 2011 |
Lactate as a hemodynamic marker in the critically ill.
Topics: Biomarkers; Cohort Studies; Critical Illness; Hemodynamics; Humans; Lactic Acid; Resuscitation; Risk | 2012 |
Lactate as a marker of energy failure in critically ill patients: hypothesis.
Topics: Acid-Base Equilibrium; Biomarkers; Critical Care; Critical Illness; Disease Progression; Energy Meta | 2005 |
[Base excess. Parameter with exceptional clinical significance].
Topics: Acid-Base Imbalance; Alkalies; Blood Gas Analysis; Critical Illness; Erythrocytes; Humans; Infusions | 2007 |
Substrate utilization in sepsis and multiple organ failure.
Topics: Critical Illness; Energy Metabolism; Fatty Acids, Omega-3; Fish Oils; Humans; Inflammation Mediators | 2007 |
Does increasing oxygen delivery improve outcome? Yes.
Topics: Critical Care; Critical Illness; Hemodynamics; Hospital Mortality; Humans; Lactic Acid; Outcome Asse | 1996 |
Metabolic acidosis in the critically ill: lessons from physical chemistry.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Carbon Dioxide; Chemical Phenomena; Chemistry, Ph | 1998 |
Interpretation of lactate levels in critical illness.
Topics: Critical Illness; Humans; Lactic Acid; Prognosis; Pyruvate Dehydrogenase Complex; Sepsis | 1998 |
Lactate and pHi: our continued search for markers of tissue distress.
Topics: Biomarkers; Critical Illness; Gastric Acidity Determination; Humans; Hydrogen-Ion Concentration; Lac | 1998 |
Energy metabolism in critically ill patients: lactate is a major oxidizable substrate.
Topics: Acute Disease; Animals; Biomarkers; Critical Illness; Energy Metabolism; Exercise; Humans; Intensive | 1999 |
Unmeasured anions: déjà vu all over again?
Topics: Acidosis, Lactic; Bias; Blood Gas Analysis; Child; Critical Care; Critical Illness; Electrolytes; Hu | 1999 |
Dysoxia and lactate.
Topics: Acidosis, Lactic; Adult; Cell Hypoxia; Child; Critical Illness; Forecasting; Humans; Lactic Acid; Ox | 1999 |
Lactic acidosis in critical illness.
Topics: Acidosis, Lactic; Bicarbonates; Blood Gas Analysis; Carbonates; Citric Acid Cycle; Critical Illness; | 1992 |
18 trials available for lactic acid and Critical Illness
| Article | Year |
|---|---|
A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial].
Topics: Albumins; Critical Illness; Electrolytes; Fluid Therapy; Humans; Hypotension, Controlled; Lactic Aci | 2022 |
Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial.
Topics: Acute Kidney Injury; Adult; Child; Child, Preschool; Chlorides; Critical Illness; Fluid Therapy; Glu | 2023 |
Effect of magnesium supplementation on lactate clearance in critically ill patients with severe sepsis: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Critical Illness; Female; Humans; Intensive Care Units; Lactic A | 2020 |
A multicenter randomized clinical trial of pharmacological vitamin B1 administration to critically ill patients who develop hypophosphatemia during enteral nutrition (The THIAMINE 4 HYPOPHOSPHATEMIA trial).
Topics: Administration, Intravenous; Adult; Aged; Biomarkers; Critical Illness; Enteral Nutrition; Female; H | 2021 |
Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial.
Topics: Adolescent; Adult; Aged; Canada; Critical Illness; Female; Fluid Therapy; Humans; Intensive Care Uni | 2017 |
Moderate intra-abdominal hypertension leads to anaerobic metabolism in the rectus abdominis muscle tissue of critically ill patients: a prospective observational study.
Topics: Adult; Anaerobiosis; Critical Illness; Female; Glutamic Acid; Humans; Intra-Abdominal Hypertension; | 2014 |
Integrated cardiopulmonary sonography: a useful tool for assessment of acute pulmonary edema in the intensive care unit.
Topics: Acute Disease; Adult; APACHE; Catheterization, Central Venous; Critical Illness; Echocardiography; H | 2014 |
Effect of high-dose dexamethasone on perioperative lactate levels and glucose control: a randomized controlled trial.
Topics: Aged; Anti-Inflammatory Agents; Area Under Curve; Blood Glucose; Cardiac Surgical Procedures; Cardio | 2015 |
[Effect of Modified Huanglian Jiedu Decoction Purgation Combined Electroacupuncture in Intervening Gastrointestinal Dysfunction of Critically Ill Patients Undergoing Abdominal Surgery].
Topics: Critical Illness; Defecation; Drugs, Chinese Herbal; Electroacupuncture; Gastrointestinal Diseases; | 2015 |
Predictors of Inadequate Linezolid Concentrations after Standard Dosing in Critically Ill Patients.
Topics: Aged; Anti-Bacterial Agents; Body Weight; Creatinine; Critical Illness; Drug Administration Schedule | 2016 |
L-alanyl-glutamine preoperative infusion in patients with critical limb ischemia subjected to distal revascularization reduces tissue damage and protects from oxidative stress.
Topics: Aged; Aged, 80 and over; Antioxidants; Biomarkers; Blood Glucose; Brazil; Creatine Kinase; Critical | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.
Topics: Aged; Biomarkers; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Intensive Car | 2010 |
Diagnostic value of soluble triggering receptor expressed on myeloid cells-1 in critically-ill, postoperative patients with suspected sepsis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Calcitonin; Calcitonin Gene-Related Peptide; Critical Il | 2013 |
Cardiovascular outcome in critically ill patients treated with continuous haemofiltration--beneficial effects of bicarbonate-buffered replacement fluids.
Topics: Acute Kidney Injury; Bicarbonates; Buffers; Cardiovascular Diseases; Creatinine; Critical Illness; D | 2002 |
Immediate metabolic effects of different nutritional regimens in critically ill medical patients.
Topics: Aged; Blood Glucose; Blood Urea Nitrogen; Body Temperature; Critical Illness; Energy Intake; Energy | 1995 |
Prognostic value of the dobutamine test in patients with sepsis syndrome and normal lactate values: a prospective, multicenter study.
Topics: Adult; Aged; Critical Illness; Dobutamine; Female; Hemodynamics; Humans; Infusions, Intravenous; Lac | 1993 |
Comparison of lactate and bicarbonate buffered haemofiltration fluids: use in critically ill patients.
Topics: Acidosis; Adult; Bicarbonates; Buffers; Critical Illness; Hemofiltration; Humans; Lactic Acid; Prosp | 1997 |
Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; | 2001 |
Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; | 2001 |
Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; | 2001 |
Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; | 2001 |
252 other studies available for lactic acid and Critical Illness
| Article | Year |
|---|---|
Understanding critically ill sepsis patients with normal serum lactate levels: results from U.S. and European ICU cohorts.
Topics: Aged; Critical Illness; Europe; Female; Hospital Mortality; Humans; Hyperlactatemia; Intensive Care | 2021 |
Clinical characteristics and prognosis in patients with urosepsis from intensive care unit in Shanghai, China: a retrospective bi-centre study.
Topics: Age Distribution; Aged; China; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; | 2021 |
Usefulness of lactate albumin ratio at admission to predict 28-day mortality in critically ill severely burned patients: A retrospective cohort study.
Topics: Albumins; Burns; Critical Illness; Humans; Lactic Acid; Male; Prognosis; Retrospective Studies | 2022 |
Prognostic value of the lactate/albumin ratio for predicting mortality in patients with pneumosepsis in intensive care units.
Topics: Adult; Critical Illness; Female; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Orga | 2022 |
Prognostic Role of MELD-Lactate in Cirrhotic Patients' Short- and Long-Term Prognosis, Stratified by Causes of Cirrhosis.
Topics: Critical Illness; End Stage Liver Disease; Humans; Lactic Acid; Liver Cirrhosis; Prognosis; Retrospe | 2022 |
Therapeutic plasma exchange for multiorgan dysfunction among critically ill pediatric patients with leukemia: A single-institutional experience.
Topics: Adult; Blood Component Removal; Child; Critical Illness; Humans; Lactic Acid; Leukemia; Multiple Org | 2022 |
Assessing the Prognostic Value of Crp/Albumin Ratio and Lactate/Albumin Ratio in Critically Ill Patients.
Topics: C-Reactive Protein; COVID-19; Critical Illness; Female; Humans; Lactic Acid; Male; Prognosis; Retros | 2022 |
Establishment of MELD-lactate clearance scoring system in predicting death risk of critically ill cirrhotic patients.
Topics: Critical Illness; End Stage Liver Disease; Humans; Lactic Acid; Liver Cirrhosis; Prognosis; Retrospe | 2022 |
Finger Test for the Diagnosis of a Critically Ill Patient with Necrotizing Fasciitis.
Topics: Aged; Critical Illness; Fasciitis, Necrotizing; Female; Humans; Lactic Acid; Leg; Soft Tissue Infect | 2022 |
Evaluation of blood thiamine concentration in hospitalized dogs with and without critical illness.
Topics: Animals; Critical Illness; DNA-Binding Proteins; Dog Diseases; Dogs; Hospitalization; Hospitals, Ani | 2022 |
Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study.
Topics: Acute Kidney Injury; Adult; Aged; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hy | 2022 |
Lactate as a Screening Tool for Critical Illness in a Pediatric Emergency Department.
Topics: Child; Critical Illness; Emergency Service, Hospital; Humans; Lactic Acid; Prognosis; Retrospective | 2023 |
Outcomes of hyperlactatemia on admission in critically ill patients with acute myocardial infarction: A retrospective study from MIMIC-IV.
Topics: Critical Illness; Heart Failure; Humans; Hyperlactatemia; Lactic Acid; Myocardial Infarction; Retros | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction.
Topics: APACHE; Critical Illness; Humans; Lactic Acid; Myocardial Infarction; Nomograms | 2022 |
Impact on outcomes of measuring lactates prior to ICU in unselected heterogeneous critically ill patients: A propensity score analysis.
Topics: Anti-Bacterial Agents; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Propensity Score | 2022 |
Impact on outcomes of measuring lactates prior to ICU in unselected heterogeneous critically ill patients: A propensity score analysis.
Topics: Anti-Bacterial Agents; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Propensity Score | 2022 |
Impact on outcomes of measuring lactates prior to ICU in unselected heterogeneous critically ill patients: A propensity score analysis.
Topics: Anti-Bacterial Agents; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Propensity Score | 2022 |
Impact on outcomes of measuring lactates prior to ICU in unselected heterogeneous critically ill patients: A propensity score analysis.
Topics: Anti-Bacterial Agents; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Propensity Score | 2022 |
The prognostic value of delta-lactate in critically ill children.
Topics: Child; Critical Illness; Humans; Intensive Care Units, Pediatric; Lactic Acid; Prognosis; Retrospect | 2023 |
The prognostic value of delta-lactate in critically ill children.
Topics: Child; Critical Illness; Humans; Intensive Care Units, Pediatric; Lactic Acid; Prognosis; Retrospect | 2023 |
The prognostic value of delta-lactate in critically ill children.
Topics: Child; Critical Illness; Humans; Intensive Care Units, Pediatric; Lactic Acid; Prognosis; Retrospect | 2023 |
The prognostic value of delta-lactate in critically ill children.
Topics: Child; Critical Illness; Humans; Intensive Care Units, Pediatric; Lactic Acid; Prognosis; Retrospect | 2023 |
Lactate/albumin ratio as a predictor of in-hospital mortality in critically ill children.
Topics: Adult; Albumins; Child; Critical Illness; Hospital Mortality; Humans; Infant, Newborn; Lactic Acid; | 2022 |
Predictive Value of Heart-Type Fatty Acid-Binding Protein for Mortality Risk in Critically Ill Patients.
Topics: Critical Illness; Fatty Acid Binding Protein 3; Humans; Lactic Acid; Procalcitonin; Prognosis; Retro | 2022 |
Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury.
Topics: Acute Kidney Injury; APACHE; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hyperla | 2023 |
Association of lactate detection with in-hospital mortality in critically ill patients with acute myocardial infarction: a retrospective cohort study.
Topics: Cohort Studies; Critical Illness; Female; Hospital Mortality; Humans; Lactic Acid; Male; Myocardial | 2023 |
The risk of venous thromboembolism and blood hyperlactatemia is associated with increased mortality among critically ill patients with Covid-19.
Topics: Adolescent; Adult; COVID-19; Critical Illness; Humans; Hyperlactatemia; Intensive Care Units; Lactic | 2023 |
The Association of the Lactate-Albumin Ratio With Mortality and Multiple Organ Dysfunction in PICU Patients.
Topics: Albumins; Child; Critical Illness; Humans; Intensive Care Units, Pediatric; Lactic Acid; Multiple Or | 2023 |
Interaction of lactate/albumin and geriatric nutritional risk index on the all-cause mortality of elderly patients with critically ill heart failure: A cohort study.
Topics: Aged; Cohort Studies; Critical Illness; Geriatric Assessment; Heart Failure; Humans; Lactic Acid; Nu | 2023 |
A matched case-control study on the effectiveness of extracorporeal cytokine adsorption in critically ill patients.
Topics: Adsorption; Case-Control Studies; Critical Illness; Cytokines; Humans; Interleukin-6; Lactic Acid; N | 2023 |
S-Adenosylhomocysteine Is a Useful Metabolic Factor in the Early Prediction of Septic Disease Progression and Death in Critically Ill Patients: A Prospective Cohort Study.
Topics: Critical Illness; Disease Progression; Humans; Hypoxia; Lactic Acid; Multiple Organ Failure; Oxygen; | 2023 |
Short-term mortality prediction using a combination of clinical and CT features: Refining the prognosis of critically ill patients in shock.
Topics: Critical Illness; Humans; Lactic Acid; Prognosis; Retrospective Studies; Tomography, X-Ray Computed | 2023 |
Predictive performance of renal resistive index, semiquantitative power Doppler ultrasound score and renal venous Doppler waveform pattern for acute kidney injury in critically ill patients and prediction model establishment: a prospective observational s
Topics: Acute Kidney Injury; Critical Illness; Humans; Lactic Acid; Ultrasonography; Ultrasonography, Dopple | 2023 |
Association of lactate/albumin ratio with in-hospital mortality in ICU patients with acute respiratory failure: A retrospective analysis based on MIMIC-IV database.
Topics: Adult; Albumins; Critical Illness; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Re | 2023 |
Association between initial microcirculation disturbance patients and mortality in patients who are critically ill: A retrospective cohort study.
Topics: Cohort Studies; Critical Illness; Hospital Mortality; Humans; Hyperlactatemia; Intensive Care Units; | 2023 |
Serum lactate level upon admission to the neuro-intensive care unit and 90-day mortality: A retrospective study.
Topics: Adult; Aged; Area Under Curve; Critical Illness; Female; Hospital Mortality; Humans; Intensive Care | 2019 |
Persistently elevated early warning scores and lactate identifies patients at high risk of mortality in suspected sepsis.
Topics: Adult; Aged; Critical Care; Critical Illness; Early Warning Score; Female; Hospital Mortality; Human | 2020 |
Prognostic performance of pancreatic stone protein in critically ill patients with sepsis.
Topics: Aged; Biomarkers; Critical Illness; Female; Humans; Lactic Acid; Lithostathine; Male; Middle Aged; O | 2019 |
Evaluation of serum 25-hydroxyvitamin D concentrations in a heterogeneous canine ICU population.
Topics: Animals; Critical Illness; Dog Diseases; Dogs; Female; Hospitalization; Intensive Care Units; Lactic | 2019 |
The Impact of Serum Glucose on the Predictive Value of Serum Lactate for Hospital Mortality in Critically Ill Surgical Patients.
Topics: Blood Glucose; Critical Illness; Female; Hospital Mortality; Humans; Lactic Acid; Male; Middle Aged; | 2019 |
Lactate indices as predictors of in-hospital mortality or 90-day survival after admission to an intensive care unit in unselected critically ill patients.
Topics: Aged; APACHE; Biomarkers; Cohort Studies; Comorbidity; Critical Illness; Female; Hospital Mortality; | 2020 |
Searching for a biochemical correlate of critical illness in obstetrics: a descriptive study of maternal lactate in patients presenting for acute care in pregnancy.
Topics: Critical Illness; Cross-Sectional Studies; Female; Humans; Lactic Acid; Obstetrics; Pregnancy; Prosp | 2022 |
Plasma lactate can improve the accuracy of the Pediatric Sequential Organ Failure Assessment Score for prediction of mortality in critically ill children: A pilot study.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Clinical Decision Rules; Critical Illness; Female; | 2020 |
A NEWS-L score to a NEWS+L score.
Topics: Aged; Critical Illness; Emergency Service, Hospital; Hospital Mortality; Humans; Lactic Acid | 2021 |
Characterization of the Inflammatory Response to Severe COVID-19 Illness.
Topics: Acute-Phase Reaction; Adult; Aged; alpha 1-Antitrypsin; Betacoronavirus; Blotting, Western; Carrier | 2020 |
Heparin-binding protein as a biomarker of gastrointestinal dysfunction in critically ill patients: a retrospective cross-sectional study in China.
Topics: Aged; Antimicrobial Cationic Peptides; APACHE; Biomarkers; Blood Proteins; Critical Illness; Cross-S | 2020 |
Lactate and lactate clearance in critically burned patients: usefulness and limitations as a resuscitation guide and as a prognostic factor.
Topics: Adult; Burns; Critical Illness; Female; Guidelines as Topic; Humans; Intensive Care Units; Lactic Ac | 2020 |
Continuous lactate monitoring in critically ill patients using microdialysis.
Topics: Critical Care; Critical Illness; Humans; Lactic Acid; Microdialysis; Shock | 2020 |
Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality.
Topics: Acute Kidney Injury; Adult; Aged; Animals; Critical Illness; Female; Gluconeogenesis; Glucose; Human | 2020 |
Elevated admission lactate levels in the emergency department are associated with increased 30-day mortality in non-trauma critically ill patients.
Topics: Aged; Critical Illness; Emergency Service, Hospital; Female; Germany; Humans; Lactic Acid; Male; Pat | 2020 |
Prognostic Value of the Lactate-Albumin Difference in Predicting 30-Day Mortality in Critically Ill Patients.
Topics: Albumins; Critical Illness; Humans; Lactic Acid; Prognosis; ROC Curve | 2021 |
Association Between the Oxygen Consumption: Lactate Ratio and Survival in Critically Ill Patients With Sepsis.
Topics: Aged; Critical Illness; Female; Hospital Mortality; Humans; Lactic Acid; Male; Middle Aged; Oxygen C | 2021 |
Bundled care in acute kidney injury in critically ill patients, a before-after educational intervention study.
Topics: Acute Kidney Injury; Adult; Aged; Arterial Pressure; Critical Illness; Deprescriptions; Disease Prog | 2020 |
Metformin use and early lactate levels in critically ill patients according to chronic and acute renal impairment.
Topics: Aged; Critical Illness; Denmark; Female; Humans; Hypoglycemic Agents; Lactic Acid; Male; Metformin; | 2020 |
Comparison of wavelength selection methods for in-vitro estimation of lactate: a new unconstrained, genetic algorithm-based wavelength selection.
Topics: Algorithms; Biomarkers; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Shock, Septic; | 2020 |
Lactate/albumin ratio: An early prognostic marker in critically ill patients.
Topics: Aged; APACHE; Area Under Curve; Cohort Studies; Critical Illness; Female; Humans; Lactic Acid; Male; | 2020 |
Combination of biomarker with clinical risk factors for prediction of severe acute kidney injury in critically ill patients.
Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Biomarkers; Clinical Decision Rules; Cont | 2020 |
Negative central venous to arterial lactate gradient in patients receiving vasopressors is associated with higher ICU 30-day mortality: a retrospective cohort study.
Topics: Aged; Arteries; Beijing; Cohort Studies; Critical Care; Critical Illness; Female; Hospital Mortality | 2021 |
Impella use in real-world cardiogenic shock patients: Sobering outcomes.
Topics: Adult; Aged; Aged, 80 and over; Critical Care; Critical Illness; Female; Heart Arrest; Heart-Assist | 2021 |
Stepwise lactate kinetics in critically ill patients: prognostic, influencing factors, and clinical phenotype.
Topics: APACHE; Blood Glucose; Critical Illness; Female; Heart Rate; Humans; Lactic Acid; Male; Middle Aged; | 2021 |
Lactate/albumin ratio is more effective than lactate or albumin alone in predicting clinical outcomes in intensive care patients with sepsis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Critical Illness; Female; Humans; Intensive Care Units; | 2021 |
Model for End-Stage Liver Disease Lactate Score and Prediction of Inpatient Mortality in Critically Ill Patients With Cirrhosis.
Topics: Critical Illness; End Stage Liver Disease; Humans; Inpatients; Intensive Care Units; Lactic Acid; Li | 2021 |
Base-excess chloride; the best approach to evaluate the effect of chloride on the acid-base status: A retrospective study.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Aged; APACHE; Chlorides; Critical Illness; Female; Human | 2021 |
The relationship between admission glucose and lactate with critical illness amongst adult patients presenting to the emergency department.
Topics: Adult; Critical Illness; Cross-Sectional Studies; Emergency Service, Hospital; Glucose; Hospital Mor | 2021 |
Evaluation of the quick sequential organ failure assessment score plus lactate in critically ill dogs.
Topics: Animals; Critical Illness; Dog Diseases; Dogs; Hospital Mortality; Intensive Care Units; Lactic Acid | 2021 |
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten | 2022 |
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten | 2022 |
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten | 2022 |
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten | 2022 |
Prediction of blood lactate values in critically ill patients: a retrospective multi-center cohort study.
Topics: Cohort Studies; Critical Illness; Humans; Lactic Acid; Retrospective Studies | 2022 |
Association between acute gastrointestinal injury and biomarkers of intestinal barrier function in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Biomarkers; Case-Control Studies; Critical Illness; Fatty Ac | 2017 |
Hyperlactatemia, Lactate Kinetics and Prediction of Citrate Accumulation in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy With Regional Citrate Anticoagulation.
Topics: Anticoagulants; Citric Acid; Critical Illness; Hospitals, University; Humans; Hyperlactatemia; Inten | 2017 |
On-line plasma lactate concentration monitoring in critically ill patients.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Central Venous Catheters; Critical Illness; Female; Glucose | 2017 |
A multifactor model for predicting mortality in critically ill patients: A multicenter prospective cohort study.
Topics: Aged; Calibration; Critical Illness; Female; Hospital Mortality; Humans; Intensive Care Units; Lacti | 2017 |
The correlation between CVP-derived parameters and the prognosis of critically ill patients.
Topics: APACHE; Central Venous Pressure; Cohort Studies; Creatinine; Critical Illness; Female; Humans; Inten | 2017 |
Serum lactate is an independent predictor of hospital mortality in critically ill patients in the emergency department: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Critical Illness; Emergency Service, Hospital; Female; | 2017 |
Hyperlactatemia in ICU patients: Incidence, causes and associated mortality.
Topics: Adult; Aged; Area Under Curve; Cardiac Surgical Procedures; Critical Illness; Female; Hospital Morta | 2017 |
The association of early combined lactate and glucose levels with subsequent renal and liver dysfunction and hospital mortality in critically ill patients.
Topics: Adult; Aged; APACHE; Critical Illness; Female; Glucose; Hospital Mortality; Hospitalization; Humans; | 2017 |
Agreement between venous and arterial blood gas analysis of acid-base status in critical care and ward patients: a retrospective cohort study.
Topics: Acid-Base Equilibrium; Arteries; Blood Gas Analysis; Carbon Dioxide; Cohort Studies; Critical Care; | 2017 |
Liver transplantation in critically ill patients: Preoperative predictive factors of post-transplant mortality to avoid futility.
Topics: Adult; Critical Illness; Female; Follow-Up Studies; Graft Rejection; Humans; Lactic Acid; Liver Fail | 2017 |
Impact of antibiotic therapy in severe community-acquired pneumonia: Data from the Infauci study.
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactams; Community-Acquired Infections; Critical Illness; D | 2018 |
Relationship of at Admission Lactate, Unmeasured Anions, and Chloride to the Outcome of Critically Ill Patients.
Topics: Acidosis; Aged; Aged, 80 and over; Anions; Blood Gas Analysis; Chlorides; Critical Illness; Female; | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.
Topics: Aged; Biomarkers; Critical Illness; Cross-Sectional Studies; Female; Hospital Mortality; Humans; Int | 2017 |
The impact of obesity in cirrhotic patients with septic shock: A retrospective cohort study.
Topics: Aged; Body Mass Index; Canada; Comorbidity; Critical Illness; Databases, Factual; Female; Hospital M | 2018 |
Are platelet volume indices related to mortality in hospitalized children on mechanical ventilation?
Topics: Adolescent; Bilirubin; Blood Platelets; Calcitonin; Child; Child, Hospitalized; Child, Preschool; Cr | 2018 |
[Effect of lactic acid levels on the prognosis of critically ill patients after cardiac and non-cardiac surgery: an analysis of 549 cases].
Topics: Critical Illness; Humans; Intensive Care Units; Lactic Acid; Prognosis; Retrospective Studies | 2018 |
Hyperlactatemia and the Importance of Repeated Lactate Measurements in Critically Ill Patients.
Topics: Adult; Aged; Aged, 80 and over; Bosnia and Herzegovina; Critical Illness; Female; Hospital Mortality | 2017 |
Prognostic Value of The Lactate/Albumin Ratio for Predicting 28-Day Mortality in Critically ILL Sepsis Patients.
Topics: Aged; Albumins; Critical Illness; Female; Humans; Lactic Acid; Male; Middle Aged; Prognosis; Retrosp | 2018 |
Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa.
Topics: Africa, Eastern; Child; Child, Preschool; Critical Illness; Female; Fever; Humans; Infant; Lactic Ac | 2018 |
Comparison of qSOFA with current emergency department tools for screening of patients with sepsis for critical illness.
Topics: Adult; Aged; Area Under Curve; Biomarkers; Cohort Studies; Communicable Diseases; Critical Illness; | 2018 |
The incidence and outcome of hyperlactatemia in patients admitted to the intensive care unit after elective surgery.
Topics: Aged; Critical Illness; Elective Surgical Procedures; Emergencies; Female; Follow-Up Studies; Hospit | 2018 |
Predictive Validity of Sepsis-3 Definitions and Sepsis Outcomes in Critically Ill Patients: A Cohort Study in 49 ICUs in Argentina.
Topics: Adult; Aged; Argentina; Cohort Studies; Comorbidity; Critical Illness; Drug Resistance, Microbial; F | 2018 |
Capillary and venous lactate measurements with a handheld device compared to venous blood-gas analysis for emergency patients.
Topics: Adult; Aged; Aged, 80 and over; Blood Gas Analysis; Critical Illness; Emergency Medical Services; Fe | 2018 |
Serum lactate level accurately predicts mortality in critically ill patients with cirrhosis with acute kidney injury.
Topics: Acute Kidney Injury; Aged; Biomarkers; Critical Illness; Databases, Factual; Female; Hospital Mortal | 2018 |
Effect of Thiamine Administration on Lactate Clearance and Mortality in Patients With Septic Shock.
Topics: Adult; Aged; Cohort Studies; Critical Illness; Female; Follow-Up Studies; Humans; Intensive Care Uni | 2018 |
Lactate Improves Prediction of Short-Term Mortality in Critically Ill Patients With Cirrhosis: A Multinational Study.
Topics: Acute-On-Chronic Liver Failure; Aged; Critical Illness; Female; Humans; Internationality; Lactic Aci | 2019 |
Feasibility of Exercise Testing in Patients Who Are Critically Ill: A Prospective, Observational Multicenter Study.
Topics: Aged; APACHE; Critical Illness; Exercise Test; Feasibility Studies; Female; Humans; Intensive Care U | 2019 |
Lactic Acidosis in a Critically Ill Patient: Not Always Sepsis.
Topics: Acidosis, Lactic; Antineoplastic Agents; Child; Critical Illness; Diagnosis, Differential; Fatal Out | 2018 |
Acute Kidney Injury in Critically Ill Children Admitted to the PICU for Diabetic Ketoacidosis. A Retrospective Study.
Topics: Acute Kidney Injury; Adolescent; Blood Glucose; Child; Child, Preschool; Critical Illness; Diabetic | 2019 |
Prognostic value of lactate in prehospital care as a predictor of early mortality.
Topics: Aged; Aged, 80 and over; Area Under Curve; Cardiovascular Diseases; Critical Illness; Emergency Medi | 2019 |
Prognostic relevance of serum lactate kinetics in critically ill patients.
Topics: Aged; Analysis of Variance; APACHE; Cohort Studies; Critical Illness; Female; Germany; Humans; Kinet | 2019 |
Lactate kinetics in critically ill: a new prognostic marker or just another brick in the wall?
Topics: Critical Illness; Humans; Kinetics; Lactic Acid; Prognosis | 2019 |
Tissue Perfusion and Prognosis in the Critically Ill-Is Renin the New Lactate?
Topics: Biomarkers; Critical Illness; Humans; Lactic Acid; Prognosis; Renin | 2019 |
Lactate and NEWS-L are fair predictors of mortality in critically ill geriatric emergency department patients.
Topics: Aged; Aged, 80 and over; Area Under Curve; Critical Illness; Emergency Service, Hospital; Female; Ge | 2020 |
Agreement between capillary and venous lactate in emergency department patients: prospective observational study.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Capillaries; Critical Illness; Emergency Service, Hospit | 2019 |
Real-world clinical experience with the percutaneous extracorporeal life support system: Results from the German Lifebridge
Topics: Aged; Cardiopulmonary Resuscitation; Cohort Studies; Critical Illness; Extracorporeal Membrane Oxyge | 2020 |
Effects of pH and the plasma or serum concentrations of total calcium, chloride, magnesium, l-lactate, and albumin on the plasma ionized calcium concentration in calves.
Topics: Animals; Calcium; Carbon Dioxide; Cattle; Cattle Diseases; Chlorides; Critical Illness; Female; Hydr | 2019 |
[Blood group as a predictor of glycemia and lactatemia in critical condition patients.]
Topics: Adult; Aged; Blood Glucose; Blood Group Antigens; Case-Control Studies; Critical Illness; Humans; Hy | 2019 |
Serum Lactate as an Independent Predictor of In-Hospital Mortality in Intensive Care Patients.
Topics: Adult; Critical Care; Critical Illness; Hospital Mortality; Humans; Intensive Care Units; Lactic Aci | 2020 |
Prognostic relevance of serum lactate kinetics: a powerful predictor but not Chuck Norris in Intensive Care Medicine.
Topics: Critical Care; Critical Illness; Humans; Kinetics; Lactic Acid; Prognosis | 2019 |
Prognostic value of serum lactate kinetics in critically ill patients with cirrhosis and acute-on-chronic liver failure: a multicenter study.
Topics: Acute-On-Chronic Liver Failure; Aged; Area Under Curve; Cohort Studies; Critical Illness; Female; Hu | 2019 |
The use of APACHE II, SOFA, SAPS 3, C-reactive protein/albumin ratio, and lactate to predict mortality of surgical critically ill patients: A retrospective cohort study.
Topics: Aged; APACHE; Biomarkers; C-Reactive Protein; Critical Care; Critical Illness; Female; Hospital Mort | 2019 |
Combining qSOFA criteria with initial lactate levels: Improved screening of septic patients for critical illness.
Topics: Aged; Cohort Studies; Critical Illness; Female; Humans; Lactic Acid; Male; Mass Screening; Middle Ag | 2020 |
Blood lactate/ATP ratio, as an alarm index and real-time biomarker in critical illness.
Topics: Adenosine Triphosphate; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arteries; Biomarker | 2013 |
Elevated adipose tissue lactate to pyruvate (L/P) ratio predicts poor outcome in critically ill patients with septic shock: a microdialysis study.
Topics: Adipose Tissue; Aged; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; Male; Mic | 2013 |
The base excess gap is not a valid tool for the quantification of unmeasured ions in cardiac surgical patients: a retrospective observational study.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Aged; Carbon Dioxide; Cardiac Surgical Procedures; Criti | 2013 |
Sequential L-lactate concentration in hospitalised equine neonates: A prospective multicentre study.
Topics: Animals; Animals, Newborn; Critical Illness; Horse Diseases; Horses; Humans; Lactic Acid; Prospectiv | 2013 |
Comparison of transverse facial venous sinus and jugular blood values in healthy and critically ill horses.
Topics: Animals; Critical Illness; Hematocrit; Horses; Lactic Acid; Prospective Studies | 2013 |
Stress hyperlactatemia modifies the relationship between stress hyperglycemia and outcome: a retrospective observational study.
Topics: Aged; APACHE; Blood Gas Analysis; Critical Illness; Cross-Sectional Studies; Female; Glucose; Hospit | 2014 |
Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; APACHE; Cohort Studies; Critical Care; Critical | 2014 |
Effectiveness of predicting in-hospital mortality in critically ill children by assessing blood lactate levels at admission.
Topics: Child, Preschool; Critical Illness; Female; Hospital Mortality; Humans; Infant; Intensive Care Units | 2014 |
Comparison of scoring systems and outcome of patients admitted to a liver intensive care unit of a tertiary referral centre with severe variceal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Critical Illness; Esophageal and Gastric Varices | 2014 |
Effects of different doses in continuous veno-venous hemofiltration on plasma lactate in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Hemofiltration; Humans; Lactic Acid; Male; | 2014 |
Lactate and glucose in critically ill patients: what goes around, comes around.
Topics: Critical Illness; Female; Glucose; Humans; Hyperglycemia; Lactic Acid; Male; Stress, Physiological | 2014 |
Lactate clearance as a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review study protocol.
Topics: Biomarkers; Cause of Death; Cohort Studies; Critical Illness; Humans; Lactic Acid; Prognosis; Resear | 2014 |
Optimizing oxygen delivery in the critically ill: the utility of lactate and central venous oxygen saturation (ScvO2) as a roadmap of resuscitation in shock.
Topics: Biomarkers; Blood Gas Analysis; Critical Illness; Humans; Lactic Acid; Oxygen; Practice Guidelines a | 2014 |
Clearing lactate is clearly better…but how much?*.
Topics: Critical Illness; Lactic Acid | 2014 |
A pilot study of quantitative capillary refill time to identify high blood lactate levels in critically ill patients.
Topics: Capillaries; Critical Illness; Female; Humans; Lactic Acid; Male; Middle Aged; Oximetry; Palpation; | 2015 |
The utility of scoring systems in critically ill cirrhotic patients admitted to a general intensive care unit.
Topics: Acute Kidney Injury; Adult; Aged; Analysis of Variance; Area Under Curve; Critical Illness; Female; | 2014 |
The prognostic value of leukocyte apoptosis in patients with severe sepsis at the emergency department.
Topics: Aged; Aged, 80 and over; Annexin A5; Apoptosis; Apoptosis Regulatory Proteins; Bacterial Infections; | 2015 |
Blunt cardiac injury in critically ill trauma patients: a single centre experience.
Topics: Adult; Biomarkers; Critical Care; Critical Illness; Electrocardiography; Female; Heart Injuries; Hos | 2015 |
Restrictive transfusion practice during extracorporeal membrane oxygenation therapy for severe acute respiratory distress syndrome.
Topics: Adolescent; Adult; Biomarkers; Critical Illness; Erythrocyte Transfusion; Extracorporeal Membrane Ox | 2015 |
[Look beyond the surface: lactate and oxygen metabolic dysfunction in critical patients].
Topics: Critical Illness; Humans; Lactates; Lactic Acid; Oxygen; Oxygen Consumption | 2014 |
[Central venous-to-arterial carbon dioxide difference in critically ill pediatric patients with septic shock].
Topics: Arterial Pressure; Blood Gas Analysis; Carbon Dioxide; Central Venous Pressure; Child, Preschool; Ch | 2014 |
Can serum L-lactate, D-lactate, creatine kinase and I-FABP be used as diagnostic markers in critically ill patients suspected for bowel ischemia.
Topics: Aged; Biomarkers; Cohort Studies; Creatine Kinase; Critical Illness; Fatty Acid-Binding Proteins; Fe | 2014 |
Effects of pH, lactate, hematocrit and potassium level on the accuracy of continuous glucose monitoring (CGM) in pediatric intensive care unit.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Critical Care; Critical Illness; Female; Hematoc | 2015 |
Prognosis of Critically ill patients in the ED and value of perfusion index measurement: a cross-sectional study.
Topics: Blood Gas Analysis; Blood Pressure; Body Temperature; Critical Illness; Cross-Sectional Studies; Eme | 2015 |
Serial blood lactate levels reflect both lactate production and clearance.
Topics: Critical Illness; Lactic Acid | 2015 |
The author replies.
Topics: Critical Illness; Lactic Acid | 2015 |
Biomarkers (Procalcitonin, C Reactive Protein, and Lactate) as Predictors of Mortality in Surgical Patients with Complicated Intra-Abdominal Infection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin G | 2015 |
Serum lactate as a marker of mortality in patients with hip fracture: A prospective study.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Critical Illness; Female; Hip Fractures; Hospital Mortal | 2015 |
Can a single lactate value predict adverse outcome in critically ill newborn?
Topics: Biomarkers; Critical Illness; Female; Humans; Infant; Infant Mortality; Infant, Newborn; Lactic Acid | 2015 |
Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients.
Topics: Aged; Cohort Studies; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Hyperlact | 2016 |
"Lactate Shift," Rather Than "Lactate Clearance," for Serial Blood Lactate Monitoring?
Topics: Critical Illness; Female; Humans; Lactic Acid; Male; Sepsis; Shock, Septic | 2015 |
The author replies.
Topics: Critical Illness; Female; Humans; Lactic Acid; Male; Sepsis; Shock, Septic | 2015 |
Arteriovenous blood gas agreement in intensive care patients with varying levels of circulatory compromise: a pilot study.
Topics: Aged; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Cohort Studies; Critical Care; Cri | 2015 |
Incidence and predictors of ischemic cerebrovascular stroke among patients on extracorporeal membrane oxygenation support.
Topics: Adult; Aged; Biomarkers; Critical Illness; Extracorporeal Membrane Oxygenation; Female; Florida; Hum | 2016 |
Relationship Between Peak Lactate and Patient Outcome Following High-Risk Gastrointestinal Surgery: Influence of the Nature of Their Surgery: Elective Versus Emergency.
Topics: Aged; Aged, 80 and over; Critical Illness; Digestive System Surgical Procedures; Elective Surgical P | 2016 |
Early lactate clearance for predicting active bleeding in critically ill patients with acute upper gastrointestinal bleeding: a retrospective study.
Topics: Adult; Chi-Square Distribution; Cohort Studies; Critical Illness; Female; Gastrointestinal Hemorrhag | 2016 |
Non-lactate strong ion difference: a clearer picture.
Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; APACHE; Chlorides; Critical Care; Critical Illn | 2016 |
[Critically ill patients with high serum lactate have poor prognosis].
Topics: Critical Illness; Humans; Intensive Care Units; Lactates; Lactic Acid; Prognosis | 2016 |
Point-of-care lactate and creatinine analysis for sick obstetric patients at Queen Elizabeth Central Hospital in Blantyre, Malawi: A feasibility study.
Topics: Adult; Creatinine; Critical Illness; Delivery, Obstetric; Feasibility Studies; Female; Health Knowle | 2016 |
Urinary Strong Ion Difference as a Marker of Renal Dysfunction. A Retrospective Analysis.
Topics: Acute Kidney Injury; Aged; Biomarkers; Calcium; Chlorides; Creatinine; Critical Illness; Female; Hum | 2016 |
Hyperlactatemia and serial lactate measurements in sick cats.
Topics: Animals; Cat Diseases; Cats; Critical Illness; Female; Hospitalization; Hyperlactatemia; Lactic Acid | 2016 |
Blood Lactate Levels Cutoff and Mortality Prediction in Sepsis-Time for a Reappraisal? a Retrospective Cohort Study.
Topics: Aged; Aged, 80 and over; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Middle Aged; P | 2016 |
Elevated Baseline Cortisol Levels Are Predictive of Bad Outcomes in Critically Ill Children.
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Biomarkers; Child; Child Mortality; Child, | 2018 |
Predicting arterial blood gas and lactate from central venous blood analysis in critically ill patients: a multicentre, prospective, diagnostic accuracy study.
Topics: Carbon Dioxide; Critical Illness; Humans; Hydrogen-Ion Concentration; Lactic Acid; Oxygen; Prospecti | 2016 |
Impact of clinical context on acute kidney injury biomarker performances: differences between neutrophil gelatinase-associated lipocalin and L-type fatty acid-binding protein.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Biomarkers; C-Reactive Protein; Critical Illness; Fatty | 2016 |
Prognostic value of the reactive oxygen species in severe sepsis and septic shock patients: a pilot study.
Topics: Aged; Aged, 80 and over; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; Male; | 2016 |
Impact of Phlebotomy Tourniquet Use on Blood Lactate Levels in Acutely Ill Patients.
Topics: Adult; Blood Chemical Analysis; Cohort Studies; Critical Illness; Emergency Service, Hospital; Femal | 2016 |
Safety and feasibility of a neuromuscular electrical stimulation chronaxie-based protocol in critical ill patients: A prospective observational study.
Topics: Adult; APACHE; Chronaxy; Critical Care; Critical Illness; Electric Stimulation Therapy; Female; Huma | 2017 |
Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study.
Topics: Acidosis, Lactic; Adult; Aged; Alcoholism; Critical Care; Critical Illness; Female; Hospital Mortali | 2016 |
Lactate clearance is associated with mortality in septic patients with acute kidney injury requiring continuous renal replacement therapy: A cohort study.
Topics: Acute Kidney Injury; Aged; Biomarkers; Brazil; Critical Illness; Female; Follow-Up Studies; Humans; | 2016 |
Combining quick Sequential Organ Failure Assessment with plasma lactate concentration is comparable to standard Sequential Organ Failure Assessment score in predicting mortality of patients with and without suspected infection.
Topics: Adult; APACHE; Area Under Curve; Biomarkers; Critical Care; Critical Illness; Female; Hospital Morta | 2017 |
Development and validation of the new ICNARC model for prediction of acute hospital mortality in adult critical care.
Topics: Adult; Age Factors; Aged; Blood Glucose; Cardiopulmonary Resuscitation; Chronic Disease; Creatinine; | 2017 |
Postoperative Meld-Lactate and Isolated Lactate Values As Outcome Predictors Following Orthotopic Liver Transplantation.
Topics: Critical Illness; Female; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Liver Trans | 2017 |
Serum Lactate Predicts Adverse Outcomes in Emergency Department Patients With and Without Infection.
Topics: Aged; Biomarkers; Critical Illness; Decision Support Techniques; Emergency Service, Hospital; Female | 2017 |
[Clinical application of Acutegastrointestinal injury grading system assocaited with clinical severity outcome in critically ill patients: a multi-center prospective, observational study].
Topics: Adult; Aged; Critical Illness; Gastrointestinal Diseases; Humans; Intensive Care Units; Lactic Acid; | 2017 |
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Stud | 2008 |
Nonischemic energy metabolic crisis in acute brain injury.
Topics: Biomarkers; Brain Injuries; Critical Care; Critical Illness; Energy Metabolism; Female; Glasgow Coma | 2008 |
Pathophysiology of critical ill patients: focus on critical oxygen delivery.
Topics: Acute Disease; Adenosine Triphosphate; Cardiac Output; Cell Hypoxia; Critical Illness; Humans; Hypox | 2008 |
Insulin resistance and beta cell function as prognostic indicator in multi-organ dysfunction syndrome.
Topics: Adolescent; Adult; Aged; APACHE; Bicarbonates; Blood Glucose; Critical Illness; Disease Progression; | 2009 |
Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Aged; Albumins; Anions; Blood Chemical Analysis; Coh | 2008 |
Prognostic value of blood lactate levels: does the clinical diagnosis at admission matter?
Topics: Aged; APACHE; Critical Illness; Female; Hemodynamics; Hospital Mortality; Humans; Intensive Care Uni | 2009 |
Effect of PaCO2 variation on standard base excess value in critically ill patients.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adult; Aged; Carbon Dioxide; Critical Illness; Female; H | 2009 |
Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill.
Topics: Acid-Base Imbalance; Alberta; Critical Illness; Female; Hospital Mortality; Humans; Incidence; Inten | 2009 |
Sepsis: a need for prehospital intervention?
Topics: Anti-Bacterial Agents; Communication; Critical Illness; Emergency Medical Services; Emergency Treatm | 2009 |
[Prognostic value of lactate clearance in the first 6 hours of intensive medicine course].
Topics: Adult; Aged; Critical Care; Critical Illness; Female; Humans; Lactic Acid; Male; Middle Aged; Progno | 2009 |
[Relationship between blood lactic level, lactic clearance, duration of lacticemia and prognosis of critically ill patients in intensive care unit].
Topics: Adult; Aged; APACHE; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; Logistic M | 2009 |
The riddle of hyperlactatemia.
Topics: Critical Illness; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid | 2009 |
Lactate: an unusually sensitive parameter of ensuing organ failure?
Topics: Biomarkers; Cause of Death; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Int | 2010 |
Clinical monitoring of systemic hemodynamics in critically ill newborns.
Topics: Acid-Base Equilibrium; Blood Circulation; Blood Pressure; Body Temperature; Critical Illness; Heart | 2010 |
Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study.
Topics: Aged; Aged, 80 and over; Australia; Critical Illness; Female; Hospital Mortality; Humans; Intensive | 2010 |
Emergency department lactate is associated with mortality in older adults admitted with and without infections.
Topics: Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Creatinine; Critical Illness; Emergenc | 2010 |
Hyperlactatemia in critical illness and cardiac surgery.
Topics: Acid-Base Imbalance; Cardiac Surgical Procedures; Critical Illness; Humans; Intensive Care Units; La | 2010 |
Prognostic value of noninvasive measures of contractility in emergency department patients with severe sepsis and septic shock undergoing early goal-directed therapy.
Topics: Aged; Aged, 80 and over; Blood Pressure; Cardiography, Impedance; Critical Illness; Emergency Servic | 2011 |
Does lactate-guided therapy really improve outcome?
Topics: Aged, 80 and over; Biomarkers; Critical Care; Critical Illness; Hospital Mortality; Humans; Lactic A | 2011 |
Is early lactate level helpful in guiding treatment?
Topics: Aged, 80 and over; Biomarkers; Critical Care; Critical Illness; Hospital Mortality; Humans; Kaplan-M | 2011 |
Interchangeability of blood gas, electrolyte and metabolite results measured with point-of-care, blood gas and core laboratory analyzers.
Topics: Blood Gas Analysis; Clinical Laboratory Techniques; Critical Illness; Electrolytes; Glucose; Hemoglo | 2011 |
Dynamic lactate indices as predictors of outcome in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Critical Illness; Female; Health Status Indicators; Hosp | 2011 |
4G/5G Polymorphism of the plasminogen activator inhibitor-1 gene is associated with multiple organ dysfunction in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Japan; Lactic Acid; Male; Middle A | 2012 |
Point: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? Yes.
Topics: Central Venous Pressure; Critical Illness; Emergency Service, Hospital; Female; Humans; Lactic Acid; | 2011 |
Lactate in the critically ill patients: an outcome marker with the times.
Topics: Critical Illness; Female; Health Status Indicators; Hospital Mortality; Humans; Intensive Care Units | 2011 |
Lactate and base deficit are predictors of mortality in critically ill patients with cancer.
Topics: Acid-Base Imbalance; Critical Illness; Female; Hospital Mortality; Humans; Lactic Acid; Male; Middle | 2011 |
Role of active nitrogen molecules in progression of septic shock.
Topics: Adult; APACHE; Creatinine; Critical Care; Critical Illness; Disease Progression; Enzyme-Linked Immun | 2012 |
The use of chloride-sodium ratio in the evaluation of metabolic acidosis in critically ill neonates.
Topics: Acidosis; Anions; Biomarkers; Blood Gas Analysis; Chlorides; Critical Illness; Electrolytes; Female; | 2012 |
[Relationship between blood lactate level and disease severity in critically ill children].
Topics: Adolescent; Child; Child, Preschool; Critical Illness; Female; Humans; Infant; Lactic Acid; Male; Pr | 2012 |
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation.
Topics: Adult; Blood Pressure; Brain; Brain Diseases, Metabolic; Brain Injuries; Cardiopulmonary Resuscitati | 2012 |
Correlation between early sublingual small vessel density and late blood lactate level in critically ill surgical patients.
Topics: Adult; Aged; Critical Illness; Female; Humans; Lactic Acid; Male; Microcirculation; Middle Aged; Mou | 2013 |
[Blood lactic acid level and APACHE II score on prognosis of critically ill elderly patients].
Topics: Aged; Aged, 80 and over; APACHE; Critical Illness; Female; Humans; Lactic Acid; Male; Middle Aged; P | 2012 |
Incidence and significance of elevated lactate in the identification of critically ill patients.
Topics: Acidosis, Lactic; Adult; Critical Illness; Emergency Medical Services; Female; Humans; Intensive Car | 2012 |
The relationship between blood lactate concentration, the Paediatric Index of Mortality 2 (PIM2) and mortality in paediatric intensive care.
Topics: Age Distribution; Biomarkers; Blood Gas Analysis; Child, Preschool; Critical Illness; Female; Hospit | 2012 |
Tolerability and safety of enteral nutrition in critically ill patients receiving intravenous vasopressor therapy.
Topics: Administration, Intravenous; Adult; Aged; Critical Illness; Dose-Response Relationship, Drug; Entera | 2013 |
Single-center experience with extracorporeal life support in 103 nonpostcardiotomy patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arterial Pressure; Biomarkers; Cardiovascular Agents; Ca | 2013 |
Changes in cerebral glycolytic activity during transport of critically ill neurotrauma patients measured with microdialysis.
Topics: Adolescent; Aged; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Critical Care; Criti | 2002 |
[Prognostic value of the pediatric index of mortality (PIM) score and lactate values in critically-ill children].
Topics: Adolescent; Child; Child, Preschool; Critical Illness; Female; Humans; Infant; Infant, Newborn; Inte | 2002 |
Impact of continuous veno-venous hemofiltration on acid-base balance.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adult; Aged; Critical Illness; Female; Hemofiltration; H | 2003 |
Low exogenous lactate clearance as an early predictor of mortality in normolactatemic critically ill septic patients.
Topics: Age Distribution; Age Factors; Aged; Blood Gas Analysis; Comorbidity; Critical Illness; Female; Hosp | 2003 |
Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients.
Topics: Aged; APACHE; Biomarkers; Blood Gas Analysis; Capnography; Carbon Dioxide; Catheterization, Swan-Gan | 2003 |
[Monitoring of lactate level and oxygen status for diagnosis and correction of hypoxia in critically ill patients (a lecture)].
Topics: Critical Illness; Hemostasis; Humans; Hypoxia; Lactic Acid; Monitoring, Physiologic; Oxygen | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness.
Topics: Alloxan; Animals; Blood Gas Analysis; Blood Glucose; Body Weight; Burns; Critical Illness; Diabetes | 2003 |
Gastric PgCO2 and Pg-aCO2 gap are related to D-lactate and not to L-lactate levels in patients with septic shock.
Topics: Acid-Base Equilibrium; Biomarkers; Blood Gas Analysis; Carbon Dioxide; Critical Illness; Gastric Muc | 2003 |
Occult hypoperfusion is associated with increased mortality in hemodynamically stable, high-risk, surgical patients.
Topics: Adult; Aged; Biomarkers; Critical Illness; Female; Hemodynamics; Humans; Hypoxia; Intensive Care Uni | 2004 |
High plasma arginine concentrations in critically ill patients suffering from hepatic failure.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Critical Illness; Cross-Sectional Studies; Fem | 2004 |
Erythropoietin and renin as biological markers in critically ill patients.
Topics: Aged; Biomarkers; Critical Illness; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Female; Hemog | 2004 |
Arterial lactate concentration, hospital survival, sepsis and SIRS in critically ill neonatal foals.
Topics: Acid-Base Equilibrium; Animals; Animals, Newborn; Blood Gas Analysis; Critical Illness; Horse Diseas | 2005 |
Near-infrared spectroscopic cerebral oxygenation reading in neonates and infants is associated with central venous oxygen saturation.
Topics: Blood Gas Analysis; Blood Pressure; Brain; Calcium; Catheterization, Central Venous; Conscious Sedat | 2005 |
Near-infrared spectroscopic cerebral oxygenation reading in neonates and infants is associated with central venous oxygen saturation.
Topics: Blood Gas Analysis; Blood Pressure; Brain; Calcium; Catheterization, Central Venous; Conscious Sedat | 2005 |
Near-infrared spectroscopic cerebral oxygenation reading in neonates and infants is associated with central venous oxygen saturation.
Topics: Blood Gas Analysis; Blood Pressure; Brain; Calcium; Catheterization, Central Venous; Conscious Sedat | 2005 |
Near-infrared spectroscopic cerebral oxygenation reading in neonates and infants is associated with central venous oxygen saturation.
Topics: Blood Gas Analysis; Blood Pressure; Brain; Calcium; Catheterization, Central Venous; Conscious Sedat | 2005 |
New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue.
Topics: Animals; Blood Substitutes; Carbohydrate Metabolism; Cattle; Cricetinae; Critical Illness; Disease M | 2005 |
Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients.
Topics: Acidosis; Cohort Studies; Critical Illness; Female; Humans; Lactic Acid; Male; Middle Aged; Retrospe | 2006 |
Rapid decrease in plasma D-lactate as an early potential predictor of diminished 28-day mortality in critically ill septic shock patients.
Topics: Aged; Aged, 80 and over; Critical Illness; Female; Humans; Kinetics; Lactic Acid; Male; Middle Aged; | 2006 |
Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Biopsy; Citrate (si)-Synthase; Critical Illn | 2006 |
Prediction of postoperative complications after urgent laparotomy by intraperitoneal microdialysis: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Lactic Acid; Laparotomy; Male; Mic | 2006 |
Prediction of postoperative complications after urgent laparotomy by intraperitoneal microdialysis: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Lactic Acid; Laparotomy; Male; Mic | 2006 |
Prediction of postoperative complications after urgent laparotomy by intraperitoneal microdialysis: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Lactic Acid; Laparotomy; Male; Mic | 2006 |
Prediction of postoperative complications after urgent laparotomy by intraperitoneal microdialysis: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Lactic Acid; Laparotomy; Male; Mic | 2006 |
Don't take vitals, take a lactate.
Topics: Critical Illness; Hospital Mortality; Humans; Lactic Acid; United States | 2007 |
Acid-base disturbances in critically ill patients with cirrhosis.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; APACHE; Critical Illness; Female; Hospital Mortality | 2007 |
Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chl | 2008 |
Effects of lactate on glucose metabolism in healthy subjects and in severely injured hyperglycemic patients.
Topics: Adolescent; Adult; Aged; Blood Glucose; Critical Illness; Energy Metabolism; Female; Glucose; Homeos | 1995 |
Relationship between blood lactate concentrations and ionized calcium, glucose, and acid-base status in critically ill and noncritically ill patients.
Topics: Acid-Base Equilibrium; Aged; Blood Glucose; Calcium; Cohort Studies; Critical Illness; Emergency Ser | 1995 |
The use and clinical importance of a substrate-specific electrode for rapid determination of blood lactate concentrations.
Topics: Blood Chemical Analysis; Confidence Intervals; Critical Care; Critical Illness; Electrodes; Emergenc | 1994 |
Arterial or mixed venous lactate measurement in critically ill children. Is there a difference?
Topics: Arteries; Child; Child, Preschool; Critical Illness; Humans; Lactates; Lactic Acid; Veins | 1994 |
Increased oxygen affinity contributes to tissue hypoxia in critically ill patients with low oxygen delivery.
Topics: Biological Transport, Active; Critical Illness; Humans; Hypoxia; Lactates; Lactic Acid; Multiple Org | 1994 |
Association between plasma ionized calcium and lactate concentration.
Topics: Calcium; Critical Illness; Humans; Ions; Lactates; Lactic Acid | 1993 |
[Hemodynamic effects of dobutamine in critical patients: discrepancies between parameters of tissue oxygenation and lactic acid].
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Case-Control Studies; Critical Illness; Dobuta | 1993 |
Acid-base responses to high-volume haemofiltration in the critically ill.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Aged; Aged, 80 and over; Critical Illness; Female; Hemofil | 1993 |
Assessment of splanchnic oxygenation by gastric tonometry in patients with acute circulatory failure.
Topics: Aged; Blood Chemical Analysis; Critical Illness; Digestive System Physiological Phenomena; Female; G | 1993 |
Identification of the critical oxygen delivery for anaerobic metabolism in critically ill septic and nonseptic humans.
Topics: Adult; Aged; Bacterial Infections; Calorimetry, Indirect; Cell Hypoxia; Cohort Studies; Critical Ill | 1993 |
Derangement in aerobic and anaerobic energy metabolism in skeletal muscle of critically ill and recovering rats.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Creatine; Critical Illness; Energy Metabolism; | 1996 |
Resuscitation of the critically ill in the ED: responses of blood pressure, heart rate, shock index, central venous oxygen saturation, and lactate.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Cell Hypoxia; Critical Illness; Emergenc | 1996 |
Continuous venovenous hemofiltration with dialysis and lactate clearance in critically ill patients.
Topics: Acidosis, Lactic; Critical Illness; Hemodiafiltration; Humans; Lactic Acid | 1997 |
Effect of continuous venovenous hemofiltration with dialysis on lactate clearance in critically ill patients.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adolescent; Adult; Aged; Critical Illness; Dialysis Solutions | 1997 |
Release of lactate by the lung in acute lung injury.
Topics: Biological Transport, Active; Case-Control Studies; Critical Illness; Humans; Hypoxia; Lactic Acid; | 1997 |
Oxygen supply dependency can characterize septic shock.
Topics: Adult; Aged; Critical Illness; Diagnosis, Differential; Female; Hemodynamics; Humans; Lactic Acid; M | 1998 |
Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients?
Topics: Arteries; Critical Illness; Dobutamine; Dose-Response Relationship, Drug; Female; Hepatic Veins; Hum | 1998 |
Evaluation of a lactate sensor for rapid repeated measurements of blood lactate concentration.
Topics: Biosensing Techniques; Critical Illness; Humans; Lactic Acid | 1998 |
Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood.
Topics: Animals; Biomarkers; Blood Platelets; Critical Illness; Erythrocytes; Female; Glycolysis; Humans; Hy | 1999 |
Hyperlactatemia and pulmonary lactate production in patients with fulminant hepatic failure.
Topics: Critical Illness; Female; Hepatic Encephalopathy; Humans; Lactic Acid; Lung; Male; Prospective Studi | 1999 |
Does blood lactate measurement have a role in the management of the critically ill patient?
Topics: Critical Illness; Humans; Lactic Acid; Patient Care Planning; Reference Values; Regional Blood Flow; | 1999 |
Lactate measurements in critically ill patients with a hand-held analyser.
Topics: Arteries; Confidence Intervals; Critical Illness; Evaluation Studies as Topic; Humans; Lactic Acid; | 1999 |
Mitochondrial redox state in the critically ill.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Biomarkers; Critical Illness; Humans; Ketone Bodi | 1999 |
Which organic acids does hemofiltrate contain in the presence of acute renal failure?
Topics: Acetoacetates; Acids; Acute Kidney Injury; Adult; APACHE; Child; Chromatography, Gas; Critical Illne | 1999 |
Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Calcitonin; Critical Care; Critical | 2000 |
Early hyperlactataemia in critically ill children.
Topics: Acidosis, Lactic; Adolescent; Child; Child, Preschool; Critical Illness; Female; Humans; Incidence; | 2000 |
[Serum lactate level as an indicator of tissue hypoxia in severely ill patients].
Topics: Acidosis, Lactic; Cell Hypoxia; Critical Illness; Humans; Lactic Acid; Risk Factors | 2000 |
Metabolic correlates of oxygen debt predict posttrauma early acute respiratory distress syndrome and the related cytokine response.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Cytokines; Enzyme-Linked Immunosorbent | 2000 |
Blood lactate determined by a portable device in critically ill patients.
Topics: Acidosis, Lactic; Critical Illness; Equipment and Supplies; Female; Humans; Lactic Acid; Male; Middl | 2000 |
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.
Topics: Adenosine; Adolescent; Adult; Blood Gas Analysis; Blood Glucose; Brain Chemistry; Brain Injuries; Ce | 2001 |
Carboxyhemoglobin and lactate levels do not correlate in critically ill patients.
Topics: Animals; Biomarkers; Blood Gas Analysis; Carboxyhemoglobin; Critical Illness; Disease Models, Animal | 1999 |
Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit.
Topics: Aged; APACHE; Critical Care; Critical Illness; Endpoint Determination; Humans; Intensive Care Units; | 2001 |
Serial measurement of arterial lactate concentrations as a prognostic indicator in relation to the incidence of disseminated intravascular coagulation in patients with systemic inflammatory response syndrome.
Topics: Analysis of Variance; Area Under Curve; Biomarkers; Cohort Studies; Critical Illness; Disseminated I | 2001 |
Osmolar gap hyponatremia in critically ill patients: evidence for the sick cell syndrome?
Topics: Amino Acids; Critical Illness; Female; Humans; Hyponatremia; Ketone Bodies; Lactic Acid; Male; Middl | 2002 |
Comparison of gastric intramucosal pH with measures of oxygen transport and consumption in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Critical Illness; Female; Gastric Mucosa; Hemo | 1992 |