lactic acid has been researched along with Craniocerebral Injuries in 26 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Specifically, induction of thiopental coma to manage severe increased intracranial pressure in seven patients was associated with a 37% reduction of lactate, 59% reduction of glutamate, and 66% reduction in aspartate in the extracellular space of the brain." | 6.68 | Lactate and excitatory amino acids measured by microdialysis are decreased by pentobarbital coma in head-injured patients. ( Cormio, M; Goodman, JC; Gopinath, SP; Robertson, CS; Valadka, AB, 1996) |
| "The purpose of this study was to compare the effect of hyperventilation and indomethacin on cerebral circulation, metabolism and pressures in patients with acute severe head injury in order to see if indomethacin may act supplementary to hyperventilation." | 3.69 | CO(2) and indomethacin vasoreactivity in patients with head injury. ( Astrup, J; Bergholt, B; Cold, GE; Dahl, B; Jensen, K; Kjaersgaard, JO; Mosdal, B, 1996) |
| "Adenosine concentrations were measured using fluorescent-based high-pressure liquid chromatography in 67 CSF samples obtained from 13 comatose (Glasgow Coma Scale score 7) adult patients who sustained a severe closed head injury." | 3.69 | Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans. ( Bell, MJ; Carcillo, JA; Clark, RS; Jackson, EK; Kochanek, PM; Marion, DW; Mi, Z; Obrist, WD; Wisneiwski, SR, 1997) |
| "According to our results, in minor head traumas, the determination of elevated serum S100B and lactate levels cannot take the place of clinical examination and the use of cranial CT." | 2.77 | [The role of blood S100B and lactate levels in minor head traumas in children and adults and correlation with brain computerized tomography]. ( Akıncı, E; Coşkun, F; Karakaş, A; Oztürk, M; Sezer, AA; Toksöz, T; Yılmaz, G, 2012) |
| "Specifically, induction of thiopental coma to manage severe increased intracranial pressure in seven patients was associated with a 37% reduction of lactate, 59% reduction of glutamate, and 66% reduction in aspartate in the extracellular space of the brain." | 2.68 | Lactate and excitatory amino acids measured by microdialysis are decreased by pentobarbital coma in head-injured patients. ( Cormio, M; Goodman, JC; Gopinath, SP; Robertson, CS; Valadka, AB, 1996) |
| "Group 2 (n=10) received head trauma without treatment and in group 3 (n=10) nimodipine was administered for 30 minutes intravenously (2 microg/kg/min) immediately after head trauma." | 1.31 | Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma. ( Ak, A; Bor, MA; Duman, A; Oğün, CO; Ustün, ME, 2001) |
| "The influence of head trauma on the pattern of response to injury has been studied." | 1.28 | Measured energy expenditure and plasma substrate and hormonal changes after severe head injury. ( Hadfield, JM; Jones, RA; Little, RA, 1992) |
| "In nine patients with severe head trauma, the concentration of neuron-specific enolase in cerebrospinal fluid and in plasma was determined and compared with the activity of creatine kinase and alpha-hydroxybutyrate dehydrogenase, and with the concentration of lactate." | 1.27 | Severe head trauma and the changes of concentration of neuron-specific enolase in plasma and in cerebrospinal fluid. ( Bender, V; Dauberschmidt, R; Gross, J; Klages, G; Marangos, PJ; Zinsmeyer, J, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.54) | 18.7374 |
| 1990's | 11 (42.31) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramos-Zúñiga, R | 1 |
| González-de la Torre, M | 1 |
| Jiménez-Maldonado, M | 1 |
| Villaseñor-Cabrera, T | 1 |
| Bañuelos-Acosta, R | 1 |
| Aguirre-Portillo, L | 1 |
| Rizo-Curiel, G | 1 |
| Jáuregui-Huerta, F | 1 |
| Nakamura, T | 1 |
| Kuroda, Y | 1 |
| Yamashita, S | 1 |
| Kawakita, K | 1 |
| Kawai, N | 1 |
| Tamiya, T | 1 |
| Itano, T | 1 |
| Nagao, S | 1 |
| Cureton, EL | 1 |
| Kwan, RO | 1 |
| Dozier, KC | 1 |
| Sadjadi, J | 1 |
| Pal, JD | 1 |
| Victorino, GP | 1 |
| Sezer, AA | 1 |
| Akıncı, E | 1 |
| Oztürk, M | 1 |
| Coşkun, F | 1 |
| Yılmaz, G | 1 |
| Karakaş, A | 1 |
| Toksöz, T | 1 |
| Oğün, CO | 2 |
| Ustün, ME | 2 |
| Duman, A | 2 |
| Gürbilek, M | 1 |
| Genç, BO | 1 |
| Nordström, CH | 1 |
| Reinstrup, P | 1 |
| Xu, W | 1 |
| Gärdenfors, A | 1 |
| Ungerstedt, U | 1 |
| Reinert, M | 2 |
| Barth, A | 1 |
| Rothen, HU | 1 |
| Schaller, B | 1 |
| Takala, J | 1 |
| Seiler, RW | 1 |
| CAPOBIANCO, A | 1 |
| RAMBALDI, M | 1 |
| VACCA, C | 1 |
| KUBO, T | 1 |
| Chiang, MF | 1 |
| Chiu, WT | 1 |
| Lin, FJ | 1 |
| Thajeb, P | 1 |
| Huang, CJ | 1 |
| Tsai, SH | 1 |
| Duane, TM | 1 |
| Dechert, T | 1 |
| Dalesio, N | 1 |
| Wolfe, LG | 1 |
| Aboutanos, MB | 1 |
| Malhotra, AK | 1 |
| Ivatury, RR | 1 |
| Khaldi, A | 1 |
| Zauner, A | 3 |
| Doppenberg, E | 2 |
| Choi, S | 1 |
| Bullock, R | 3 |
| O'Rourke, J | 1 |
| Sheeran, P | 1 |
| Heaney, M | 1 |
| Talbot, R | 1 |
| Geraghty, M | 1 |
| Costello, J | 1 |
| McDonnell, C | 1 |
| Newell, J | 1 |
| Mannion, D | 1 |
| Dauberschmidt, R | 1 |
| Marangos, PJ | 1 |
| Zinsmeyer, J | 1 |
| Bender, V | 1 |
| Klages, G | 1 |
| Gross, J | 1 |
| Kendall, AP | 1 |
| Lin, ES | 1 |
| Oh, TE | 1 |
| Dahl, B | 1 |
| Bergholt, B | 1 |
| Cold, GE | 1 |
| Astrup, J | 1 |
| Mosdal, B | 1 |
| Jensen, K | 1 |
| Kjaersgaard, JO | 1 |
| Goodman, JC | 2 |
| Gopinath, SP | 2 |
| Valadka, AB | 2 |
| Narayan, RK | 1 |
| Grossman, RG | 1 |
| Simpson, RK | 1 |
| Robertson, CS | 2 |
| Cormio, M | 1 |
| Douzinas, EE | 1 |
| Tsidemiadou, PD | 1 |
| Pitaridis, MT | 1 |
| Andrianakis, I | 1 |
| Bobota-Chloraki, A | 1 |
| Katsouyanni, K | 1 |
| Sfyras, D | 1 |
| Malagari, K | 1 |
| Roussos, C | 1 |
| Clark, RS | 1 |
| Carcillo, JA | 1 |
| Kochanek, PM | 1 |
| Obrist, WD | 1 |
| Jackson, EK | 1 |
| Mi, Z | 1 |
| Wisneiwski, SR | 1 |
| Bell, MJ | 1 |
| Marion, DW | 1 |
| Soukup, J | 2 |
| Menzel, M | 2 |
| Young, HF | 1 |
| Condon, B | 1 |
| Oluoch-Olunya, D | 1 |
| Hadley, D | 1 |
| Teasdale, G | 1 |
| Wagstaff, A | 1 |
| Doppenberg, EM | 1 |
| Reinert, MM | 1 |
| Ak, A | 1 |
| Bor, MA | 1 |
| Hadfield, JM | 1 |
| Little, RA | 1 |
| Jones, RA | 1 |
| Persson, L | 1 |
| Hillered, L | 1 |
5 trials available for lactic acid and Craniocerebral Injuries
| Article | Year |
|---|---|
Postconcussion syndrome and mild head injury: the role of early diagnosis using neuropsychological tests and functional magnetic resonance/spectroscopy.
Topics: Adolescent; Adult; Amnesia, Retrograde; Aspartic Acid; Brain Concussion; Craniocerebral Trauma; Cros | 2014 |
Hyperbaric oxygen therapy for consciousness disturbance following head injury in subacute phase.
Topics: Adult; Aged; Cerebrovascular Circulation; Child; Consciousness Disorders; Craniocerebral Trauma; Fem | 2008 |
[The role of blood S100B and lactate levels in minor head traumas in children and adults and correlation with brain computerized tomography].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain; Child; Child, Preschool; Craniocerebral Trauma; F | 2012 |
Assessment of the lower limit for cerebral perfusion pressure in severe head injuries by bedside monitoring of regional energy metabolism.
Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Brain Chemistry; Brain Injuries; Cerebrovascular Circul | 2003 |
Lactate and excitatory amino acids measured by microdialysis are decreased by pentobarbital coma in head-injured patients.
Topics: Adolescent; Adult; Brain Chemistry; Coma; Craniocerebral Trauma; Excitatory Amino Acids; Female; Hum | 1996 |
21 other studies available for lactic acid and Craniocerebral Injuries
| Article | Year |
|---|---|
A different view of lactate in trauma patients: protecting the injured brain.
Topics: Adult; Craniocerebral Trauma; Female; Glasgow Coma Scale; Humans; Lactic Acid; Male; Middle Aged; Re | 2010 |
Correlation between tissue lactate levels and electroencephalogram in evaluating the severity of experimental head trauma.
Topics: Animals; Body Weight; Brain; Craniocerebral Trauma; Electroencephalography; Female; Lactic Acid; Mal | 2002 |
Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury.
Topics: Adolescent; Adult; Aged; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Cranioc | 2003 |
[Modifications of lactic and pyruvic acids in the blood and cerebrospinal fluid in cranial trauma].
Topics: Blood; Cerebrospinal Fluid; Craniocerebral Trauma; Humans; Lactic Acid; Pyruvates; Pyruvic Acid; Wou | 1952 |
[The effect of ATP and AMP in experimental head injury with special reference to the glycogen and lactate contents of brain tissue].
Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Brain; Craniocerebral Trauma; | 1961 |
Multiparametric analysis of cerebral substrates and nitric oxide delivery in cerebrospinal fluid in patients with intracerebral haemorrhage: correlation with hemodynamics and outcome.
Topics: Adult; Aged; Amino Acids; Carbohydrates; Cerebral Hemorrhage; Cerebrospinal Fluid; Cerebrovascular C | 2006 |
Is blood sugar the next lactate?
Topics: Adult; Age Factors; Bacterial Infections; Blood Glucose; Cause of Death; Craniocerebral Trauma; Crit | 2006 |
High extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure.
Topics: Adolescent; Adult; Astrocytes; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Cran | 2000 |
Effects of sequential changes from conventional ventilation to high-frequency oscillatory ventilation at increasing mean airway pressures in an ovine model of combined lung and head injury.
Topics: Analysis of Variance; Animals; Blood Flow Velocity; Carbon Dioxide; Cerebral Infarction; Cerebrovasc | 2007 |
Severe head trauma and the changes of concentration of neuron-specific enolase in plasma and in cerebrospinal fluid.
Topics: Adult; Aged; Craniocerebral Trauma; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Neuron | 1983 |
Leukotriene B4 as a marker of cerebral dysfunction.
Topics: Adolescent; Adult; Aged; Biomarkers; Brain Ischemia; Craniocerebral Trauma; Female; Humans; Intracra | 1995 |
CO(2) and indomethacin vasoreactivity in patients with head injury.
Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Craniocerebral Trauma; Hum | 1996 |
Lactic acid and amino acid fluctuations measured using microdialysis reflect physiological derangements in head injury.
Topics: Adult; Amino Acids; Brain; Brain Death; Craniocerebral Trauma; Extracellular Space; Humans; Intracra | 1996 |
The regional production of cytokines and lactate in sepsis-related multiple organ failure.
Topics: Aged; Craniocerebral Trauma; Cytokines; Female; Humans; Interleukin-1; Interleukin-6; Lactic Acid; L | 1997 |
Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans.
Topics: Adenosine; Adolescent; Adult; Arteries; Cerebrovascular Circulation; Chromatography, High Pressure L | 1997 |
Extended neuromonitoring: new therapeutic opportunities?
Topics: Adolescent; Adult; Body Temperature; Brain; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circula | 1998 |
Early 1H magnetic resonance spectroscopy of acute head injury: four cases.
Topics: Acute Disease; Adult; Brain; Craniocerebral Trauma; Female; Glasgow Coma Scale; Humans; Lactic Acid; | 1998 |
Increased inspired oxygen concentration as a factor in improved brain tissue oxygenation and tissue lactate levels after severe human head injury.
Topics: Adult; Aged; Brain; Case-Control Studies; Craniocerebral Trauma; Glucose; Humans; Hyperoxia; Lactic | 1999 |
Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma.
Topics: Animals; Calcium Channel Blockers; Craniocerebral Trauma; Female; Lactic Acid; Male; Malondialdehyde | 2001 |
Measured energy expenditure and plasma substrate and hormonal changes after severe head injury.
Topics: Adolescent; Adult; Blood Glucose; Craniocerebral Trauma; Energy Metabolism; Fatty Acids, Nonesterifi | 1992 |
Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis.
Topics: Adult; Amino Acids; Craniocerebral Trauma; Critical Care; Dialysis; Female; Frontal Lobe; Humans; Hy | 1992 |