Page last updated: 2024-10-17

lactic acid and Coronary Artery Stenosis

lactic acid has been researched along with Coronary Artery Stenosis in 16 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" In this study, hemodynamics, transmural high-energy phosphate (HEP), 2-deoxyglucose-6-phosphate (2-DGP) levels, and myocardial blood flow (MBF) were determined under basal conditions, during dobutamine infusion (DOB: 20 microg x kg(-1) x min(-1) iv), and during coronary stenosis + DOB + 2-deoxyglucose (2-DG) infusion."3.74Transmural distribution of metabolic abnormalities and glycolytic activity during dobutamine-induced demand ischemia. ( Eijgelshoven, MH; Jameel, MN; Mansoor, A; Wang, X; Zhang, J, 2008)
" The primary endpoint was a composite of major adverse cardiac events (MACE) at 180+/-14 days and expected to be below 20%."2.74The ProLimus trial: a prospective, non-randomised, multicentre trial to evaluate the safety and clinical performance of the pimecrolimus eluting stent system (ProGenic). ( Agostoni, P; Birkemeyer, R; Grube, E; Haine, S; Haude, M; Jung, W; Müller, R; Sarno, G; van Langenhove, G; Verheye, S; Vrints, C; Wijns, W; Willems, T, 2009)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (62.50)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naghipoor, J1
Rabczuk, T1
Ali, MT1
Martin, K1
Kumar, AH1
Cavallin, E1
Pierrou, S1
Gleeson, BM1
McPheat, WL1
Turner, EC1
Huang, CL1
Khider, W1
Vaughan, C1
Caplice, NM1
Vesga, B1
Hernandez, H1
Moncada, M1
Gasior, P1
Higuera, S1
Dager, A1
Arana, C1
Delgado, JA1
Généreux, P1
Maehara, A1
Granada, JF1
Koizumi, K1
Shin, H1
Matayoshi, T1
Yozu, R1
Wang, Y1
Liu, XC1
Zhao, J1
Kong, XR1
Shi, RF1
Zhao, XB1
Song, CX1
Liu, TJ1
Lu, F1
Verheye, S1
Sarno, G1
Müller, R1
Birkemeyer, R1
Vrints, C1
Jung, W1
Agostoni, P1
van Langenhove, G1
Haine, S1
Willems, T1
Haude, M1
Grube, E2
Wijns, W1
Rodriguez, AE1
Vigo, CF1
Delacasa, A1
Mieres, J1
Fernandez-Pereira, C1
Bernardi, V1
Bettinoti, M1
Rodriguez-Granillo, AM1
Rodriguez-Granillo, G1
Santaera, O1
Curotto, V1
Rubilar, B1
Tronge, J1
Palacios, IF1
Antoniucci, D1
Kadota, K1
Muramatsu, T1
Iwabuchi, M1
Saito, S1
Hayashi, Y1
Ikari, Y1
Nanto, S1
Fujii, K1
Inoue, N1
Namiki, A1
Kimura, T1
Mitsudo, K1
Flege, C1
Vogt, F1
Höges, S1
Jauer, L1
Borinski, M1
Schulte, VA1
Hoffmann, R1
Poprawe, R1
Meiners, W1
Jobmann, M1
Wissenbach, K1
Blindt, R1
Fallavollita, JA1
Malm, BJ1
Canty, JM1
Willigers, HM1
Prinzen, FW1
Roekaerts, PM1
de Lange, S1
Durieux, ME1
Sonoda, S1
Ikeno, F1
Honda, Y1
Kar, S1
Chan, C1
Gerckens, U1
Lansky, AJ1
Fitzgerald, PJ1
Bhargava, B1
Reddy, NK1
Karthikeyan, G1
Raju, R1
Mishra, S1
Singh, S1
Waksman, R1
Virmani, R1
Somaraju, B1
Sidi, A2
Muehlschlegel, JD2
Muehschlegel, JD1
Kirby, DS2
Lobato, EB2
Jameel, MN1
Wang, X1
Eijgelshoven, MH1
Mansoor, A1
Zhang, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison Among a Paclitaxel Eluting Stent With Biodegradable Polymer Versus an Uncoated Bare Metal Stent. A Prospective, Multicentric and Randomized Study.(EUCATAX Trial)[NCT00825279]Phase 4300 participants (Actual)Interventional2007-08-31Completed
Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518]250 participants (Anticipated)Interventional2021-05-27Recruiting
Prospective, Randomized Trial of 3 Rapamycin-Eluting Stents With Different Polymer Coating Strategies For The Reduction of Coronary Restenosis (ISAR-TEST-3)[NCT00350454]Phase 4605 participants (Actual)Interventional2006-06-30Completed
Clinical and Angiographic Evaluation of Paclitaxel Eluting, Non-Polymeric, Nanoporous Carbon-Carbon Coated, Cobalt-Chromium Stent[NCT00428662]200 participants Interventional2007-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for lactic acid and Coronary Artery Stenosis

ArticleYear
The ProLimus trial: a prospective, non-randomised, multicentre trial to evaluate the safety and clinical performance of the pimecrolimus eluting stent system (ProGenic).
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 5, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Belgium; Cardiovascular Agents; Chromium Alloys; Coronary Angi

2009
Efficacy and safety of a double-coated paclitaxel-eluting coronary stent: the EUCATAX trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011, Feb-15, Volume: 77, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Argentina; Cardiovascular Agents; Chi-Square Distribution; Coa

2011
Randomized comparison of the Nobori biolimus A9-eluting stent with the sirolimus-eluting stent in patients with stenosis in native coronary arteries.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Nov-01, Volume: 80, Issue:5

    Topics: Aged; Cardiovascular Agents; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary

2012
Six- and twelve-month results from first human experience using everolimus-eluting stents with bioabsorbable polymer.
    Circulation, 2004, May-11, Volume: 109, Issue:18

    Topics: Aged; Anticoagulants; Catheterization; Cineangiography; Coated Materials, Biocompatible; Comorbidity

2004

Other Studies

12 other studies available for lactic acid and Coronary Artery Stenosis

ArticleYear
A mechanistic model for drug release from PLGA-based drug eluting stent: A computational study.
    Computers in biology and medicine, 2017, 11-01, Volume: 90

    Topics: Computer Simulation; Coronary Artery Disease; Coronary Stenosis; Coronary Vessels; Drug-Eluting Sten

2017
A novel CX3CR1 antagonist eluting stent reduces stenosis by targeting inflammation.
    Biomaterials, 2015, Volume: 69

    Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Ste

2015
Three-month evaluation of strut healing using a novel optical coherence tomography analytical method following bioresorbable polymer everolimus-eluting stent implantation in humans: the TIMELESS study.
    Coronary artery disease, 2017, Volume: 28, Issue:2

    Topics: Absorbable Implants; Acute Coronary Syndrome; Aged; Cardiovascular Agents; Chromium; Coronary Angiog

2017
Comparison of active and passive coronary perfusion in off-pump coronary artery bypass grafting.
    Interactive cardiovascular and thoracic surgery, 2008, Volume: 7, Issue:6

    Topics: Animals; Coronary Artery Bypass, Off-Pump; Coronary Circulation; Coronary Stenosis; Disease Models,

2008
Degradable PLGA scaffolds with basic fibroblast growth factor: experimental studies in myocardial revascularization.
    Texas Heart Institute journal, 2009, Volume: 36, Issue:2

    Topics: Angiogenesis Inducing Agents; Animals; Cell Proliferation; Coronary Circulation; Coronary Stenosis;

2009
Development and characterization of a coronary polylactic acid stent prototype generated by selective laser melting.
    Journal of materials science. Materials in medicine, 2013, Volume: 24, Issue:1

    Topics: Biocompatible Materials; Cells, Cultured; Chromatography, Gel; Coronary Stenosis; Humans; Lactic Aci

2013
Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function, and oxygen consumption at rest.
    Circulation research, 2003, Jan-10, Volume: 92, Issue:1

    Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Animals; Blood Flow Velocity; Blood Pressure; C

2003
Dexmedetomidine decreases perioperative myocardial lactate release in dogs.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Coronary Circulation; Coronary Stenosis; Depress

2003
A novel paclitaxel-eluting porous carbon-carbon nanoparticle coated, nonpolymeric cobalt-chromium stent: evaluation in a porcine model.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 67, Issue:5

    Topics: Analysis of Variance; Animals; Carbon; Chromium; Coated Materials, Biocompatible; Cobalt; Coronary A

2006
Treating metabolic impairment and myocardial stunning with phosphodiesterase inhibitor type III, milrinone, administered prior to coronary artery occlusion in the presence of calcium channel blockade in pigs.
    Annals of cardiac anaesthesia, 2007, Volume: 10, Issue:1

    Topics: Analysis of Variance; Animals; Biomarkers; Blood Pressure; Calcium Channel Blockers; Cardiac Output;

2007
Administration of milrinone before ischemia, in the presence of beta-blockade, to treat metabolic impairment and myocardial stunning in pigs.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Coronary S

2008
Transmural distribution of metabolic abnormalities and glycolytic activity during dobutamine-induced demand ischemia.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Stenosis; Disease Models, Animal; Do

2008