lactic acid has been researched along with Colonic Neoplasms in 92 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We therefore hypothesised that lactic acidosis may confer resistance to Akt inhibition." | 7.96 | Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells. ( Aboagye, EO; Barnes, EME; Benito, A; Herendi, L; Keun, HC; Nijhuis, A; Siskos, AP; Xu, Y, 2020) |
| "Metabolic profiles of human colon cancer cells have been extensively studied, but comparison with non-tumour counterparts has been neglected." | 5.40 | Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study. ( Alcarraz-Vizán, G; Cascante, M; Moyer, MP; Sánchez-Tena, S, 2014) |
| " We therefore hypothesised that lactic acidosis may confer resistance to Akt inhibition." | 3.96 | Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells. ( Aboagye, EO; Barnes, EME; Benito, A; Herendi, L; Keun, HC; Nijhuis, A; Siskos, AP; Xu, Y, 2020) |
| "In this study, we generated and characterized hyaluronate-PEG-Chitosan-Lactate (H-PCL) nanoparticles (NPs) to simultaneously deliver IL6-specific siRNA and BV6 to 4T1 (breast cancer) and CT26 (colon cancer) cells, and investigate the anti-tumor properties of this combination therapy both in vitro and in vivo." | 3.96 | Codelivery of BV6 and anti-IL6 siRNA by hyaluronate-conjugated PEG-chitosan-lactate nanoparticles inhibits tumor progression. ( Ahmadi, A; Boroumand-Noughabi, S; Hassannia, H; Heydari, M; Hojjat-Farsangi, M; Izadi, S; Jadidi-Niaragh, F; Karoon Kiani, F; Keramati, MR; Masjedi, A; Mohammadi, H; Sadat Eshaghi, F; Salimifard, S; Shahdadnejad, K, 2020) |
| " Noteworthy, oxamate and galloflavin, two inhibitors of LDH activity which reduce lactate production in cells, were found to relieve the inflammation-induced effects." | 3.85 | Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells. ( Di Ianni, L; Di Stefano, G; Govoni, M; Manerba, M; Recanatini, M; Roberti, M, 2017) |
| " These measurements indicate that apoptosis was the primary mechanism of cell death; acidity was not caused by lactic acid; and cell death was caused by depletion of carbon sources and not hypoxia." | 3.80 | Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture. ( Forbes, NS; Kasinskas, RW; Venkatasubramanian, R, 2014) |
| " injections of azoxymethane at a dose of 10 mg/kg body weight once weekly for 2 weeks." | 3.72 | Energy restriction reduces the number of advanced aberrant crypt foci and attenuates the expression of colonic transforming growth factor beta and cyclooxygenase isoforms in Zucker obese (fa/fa) rats. ( Bird, RP; Raju, J, 2003) |
| "However, their functions in colon cancer and the underlying mechanism remain unclear." | 1.56 | IC261, a specific inhibitor of CK1δ/ε, promotes aerobic glycolysis through p53-dependent mechanisms in colon cancer. ( Chang, H; Hu, Y; Jia, H; Li, J; Liu, M; Lu, M; Lu, S; Ren, F; Zhong, J; Zhou, M, 2020) |
| "T47D breast cancer cells were further evaluated for time-dependent and dose-dependent effects on (18)F-FDG uptake, lactate release, oxygen consumption rate (OCR), reactive oxygen species (ROS) production, and mitochondrial membrane potential." | 1.43 | Molecular mechanism of (18)F-FDG uptake reduction induced by genipin in T47D cancer cell and role of uncoupling protein-2 in cancer cell glucose metabolism. ( Cho, YS; Choe, YS; Jung, KH; Lee, JH; Lee, KH; Moon, SH; Park, JW, 2016) |
| " Despite its imperative biological activities, chemical instability, photo-instability and poor bioavailability limits its utilization as an effective therapeutic agent." | 1.42 | Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells. ( Dhumale, S; Pandey, SM; Pathak, C; Sharma, A; Waghela, BN, 2015) |
| "Metabolic profiles of human colon cancer cells have been extensively studied, but comparison with non-tumour counterparts has been neglected." | 1.40 | Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study. ( Alcarraz-Vizán, G; Cascante, M; Moyer, MP; Sánchez-Tena, S, 2014) |
| "Colon cancer is one of the major causes of death in the Western world." | 1.40 | Synthesis and characterization of bioactive conjugated near-infrared fluorescent proteinoid-poly(L-lactic acid) hollow nanoparticles for optical detection of colon cancer. ( Corem-Salkmon, E; Grinberg, I; Kolitz-Domb, M; Margel, S, 2014) |
| "5-Fluorouracil (5-FU) was suspended in an ethyl acetate solution of poly D,L-lactide-co-glycolic acid (PLGA) and a vacuum drying method was applied." | 1.39 | Hemostatic absorbable gelatin sponge loaded with 5-fluorouracil for treatment of tumors. ( Chen, Y; Sun, W; Yuan, W, 2013) |
| " It is known that mTHPC possesses a significant phototoxicity against a variety of human cancer cells in vitro but also exhibits dark toxicity and can cause adverse effects (especially skin photosensitization)." | 1.37 | Comparison of intracellular accumulation and cytotoxicity of free mTHPC and mTHPC-loaded PLGA nanoparticles in human colon carcinoma cells. ( Engel, A; Knobloch, T; Langer, K; Löw, K; von Briesen, H; Wagner, S; Wiehe, A, 2011) |
| "The purpose of this work was to assess synergistic inhibitory responses of a novel chemopreventive combination regimen of drugs namely, aspirin in combination with calcium and folic acid on two human colon cancer cell lines, HT-29 and SW-480." | 1.36 | Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer. ( Chaudhary, A; Kanthamneni, N; Prabhu, S; Wang, J, 2010) |
| "Colon carcinoma is one of the common malignant tumors and has high morbidity and mortality in the world." | 1.36 | The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma. ( Cui, FY; Li, SZ; Li, ZY; Mao, YQ; Mu, B; Song, XR; Wei, YQ; Yang, L, 2010) |
| "Human colon cancer cells and primary colon cancer silence the gene coding for LDH (lactate dehydrogenase)-B and up-regulate the gene coding for LDH-A, resulting in effective conversion of pyruvate into lactate." | 1.35 | Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. ( Carswell, KN; Ganapathy, V; Prasad, PD; Thangaraju, M, 2009) |
| "We determined in HT-29 human colon cancer cells whether ALA is able to affect apoptosis, as an important parameter disregulated in tumour development." | 1.33 | alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation. ( Daniel, H; Nickel, A; Wenzel, U, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (4.35) | 18.7374 |
| 1990's | 10 (10.87) | 18.2507 |
| 2000's | 13 (14.13) | 29.6817 |
| 2010's | 52 (56.52) | 24.3611 |
| 2020's | 13 (14.13) | 2.80 |
| Authors | Studies |
|---|---|
| Govindarasu, M | 1 |
| Abirami, P | 1 |
| Alharthi, SS | 1 |
| Thiruvengadam, M | 1 |
| Rajakumar, G | 1 |
| Vaiyapuri, M | 1 |
| Marzo, F | 1 |
| Jauregui, P | 1 |
| Barrenetxe, J | 1 |
| Martínez-Peñuela, A | 1 |
| Ibañez, FC | 1 |
| Milagro, FI | 1 |
| Wang, S | 1 |
| Wang, Y | 3 |
| Li, S | 1 |
| Nian, S | 1 |
| Xu, W | 1 |
| Liang, F | 1 |
| Phatak, N | 1 |
| Bhattacharya, S | 1 |
| Shah, D | 1 |
| Manthalkar, L | 1 |
| Sreelaya, P | 1 |
| Jain, A | 1 |
| Altinok, O | 1 |
| Poggio, JL | 1 |
| Stein, DE | 1 |
| Bowne, WB | 1 |
| Shieh, AC | 1 |
| Snyder, NW | 1 |
| Orynbayeva, Z | 1 |
| Biagioni, A | 1 |
| Laurenzana, A | 1 |
| Chillà, A | 1 |
| Del Rosso, M | 1 |
| Andreucci, E | 1 |
| Poteti, M | 1 |
| Bani, D | 1 |
| Guasti, D | 1 |
| Fibbi, G | 1 |
| Margheri, F | 1 |
| Liu, M | 2 |
| Hu, Y | 1 |
| Lu, S | 1 |
| Lu, M | 1 |
| Li, J | 3 |
| Chang, H | 1 |
| Jia, H | 1 |
| Zhou, M | 1 |
| Ren, F | 1 |
| Zhong, J | 1 |
| Barnes, EME | 1 |
| Xu, Y | 1 |
| Benito, A | 1 |
| Herendi, L | 1 |
| Siskos, AP | 1 |
| Aboagye, EO | 1 |
| Nijhuis, A | 1 |
| Keun, HC | 1 |
| Chen, QW | 1 |
| Wang, JW | 1 |
| Wang, XN | 1 |
| Fan, JX | 1 |
| Liu, XH | 1 |
| Li, B | 1 |
| Han, ZY | 1 |
| Cheng, SX | 1 |
| Zhang, XZ | 1 |
| Fu, R | 1 |
| Yang, P | 1 |
| Amin, S | 1 |
| Li, Z | 1 |
| Salimifard, S | 1 |
| Karoon Kiani, F | 1 |
| Sadat Eshaghi, F | 1 |
| Izadi, S | 1 |
| Shahdadnejad, K | 1 |
| Masjedi, A | 1 |
| Heydari, M | 1 |
| Ahmadi, A | 1 |
| Hojjat-Farsangi, M | 1 |
| Hassannia, H | 1 |
| Mohammadi, H | 1 |
| Boroumand-Noughabi, S | 1 |
| Keramati, MR | 1 |
| Jadidi-Niaragh, F | 1 |
| Wang, Z | 1 |
| Xu, F | 1 |
| Hu, J | 1 |
| Zhang, H | 2 |
| Cui, L | 2 |
| Lu, W | 1 |
| He, W | 1 |
| Wang, X | 1 |
| Li, M | 1 |
| Xiong, W | 1 |
| Xie, C | 1 |
| Liu, Y | 2 |
| Zhou, P | 1 |
| Liu, J | 1 |
| Huang, P | 1 |
| Qin, XF | 1 |
| Xia, X | 1 |
| Qu, J | 1 |
| Sun, Z | 1 |
| Peng, C | 1 |
| Li, D | 1 |
| Yan, W | 1 |
| Xu, Z | 1 |
| Hou, Y | 1 |
| Shen, S | 1 |
| Chen, P | 1 |
| Wang, T | 1 |
| Han, N | 1 |
| Pang, L | 1 |
| Xu, J | 1 |
| Hyun, H | 1 |
| Park, J | 1 |
| Yeo, Y | 1 |
| Taghavi, S | 1 |
| Ramezani, M | 1 |
| Alibolandi, M | 1 |
| Abnous, K | 1 |
| Taghdisi, SM | 1 |
| Xiang, F | 1 |
| Huang, Y | 2 |
| Shi, L | 1 |
| Hu, C | 1 |
| Yang, Y | 1 |
| Wang, D | 1 |
| He, N | 1 |
| Tao, K | 1 |
| Wu, K | 1 |
| Wang, G | 1 |
| Pretel, E | 1 |
| Arias, JL | 1 |
| Cabeza, L | 1 |
| Melguizo, C | 1 |
| Prados, J | 1 |
| Mallandrich, M | 1 |
| Suñer, J | 1 |
| Clares, B | 1 |
| Leelakanok, N | 1 |
| Geary, SM | 1 |
| Salem, AK | 1 |
| Yin, DT | 1 |
| Fu, Y | 1 |
| Zhao, XH | 1 |
| Yang, KM | 1 |
| Kim, K | 1 |
| Rai, A | 1 |
| Greening, DW | 1 |
| Chen, M | 1 |
| Xu, R | 1 |
| Ji, H | 1 |
| Simpson, RJ | 1 |
| Martin, ES | 1 |
| Belmont, PJ | 1 |
| Sinnamon, MJ | 1 |
| Richard, LG | 1 |
| Yuan, J | 1 |
| Coffee, EM | 1 |
| Roper, J | 1 |
| Lee, L | 1 |
| Heidari, P | 1 |
| Lunt, SY | 1 |
| Goel, G | 1 |
| Ji, X | 1 |
| Xie, Z | 1 |
| Xie, T | 1 |
| Lamb, J | 1 |
| Weinrich, SL | 1 |
| VanArsdale, T | 1 |
| Bronson, RT | 1 |
| Xavier, RJ | 1 |
| Vander Heiden, MG | 1 |
| Kan, JL | 1 |
| Mahmood, U | 1 |
| Hung, KE | 1 |
| Zhao, H | 1 |
| Wu, F | 1 |
| Cai, Y | 1 |
| Chen, Y | 3 |
| Wei, L | 1 |
| Liu, Z | 1 |
| Yuan, W | 2 |
| Sun, W | 1 |
| Alcarraz-Vizán, G | 1 |
| Sánchez-Tena, S | 1 |
| Moyer, MP | 1 |
| Cascante, M | 1 |
| Li, P | 1 |
| Chen, L | 1 |
| Gao, W | 1 |
| Zeng, F | 1 |
| Kong, LX | 1 |
| Kasinskas, RW | 1 |
| Venkatasubramanian, R | 1 |
| Forbes, NS | 1 |
| Wei, Z | 1 |
| Mei, Z | 1 |
| Zhang, D | 1 |
| Ramirez, MS | 1 |
| Lee, J | 1 |
| Walker, CM | 1 |
| Kingsley, CV | 1 |
| De La Cerda, J | 1 |
| Maldonado, KL | 1 |
| Lai, SY | 1 |
| Bankson, JA | 1 |
| Shakeri-Zadeh, A | 1 |
| Shiran, MB | 1 |
| Khoee, S | 1 |
| Sharifi, AM | 1 |
| Ghaznavi, H | 1 |
| Khoei, S | 1 |
| Kolitz-Domb, M | 2 |
| Grinberg, I | 2 |
| Corem-Salkmon, E | 2 |
| Margel, S | 2 |
| Andrieu, T | 1 |
| Fustier, P | 1 |
| Alikhani-Koupaei, R | 1 |
| Ignatova, ID | 1 |
| Guettinger, A | 1 |
| Frey, FJ | 1 |
| Frey, BM | 1 |
| Bloch, M | 1 |
| Jablonowski, L | 1 |
| Yavin, E | 1 |
| Moradov, D | 1 |
| Djavsarov, I | 1 |
| Nyska, A | 1 |
| Wheatley, M | 1 |
| Rubinstein, A | 1 |
| Saito, K | 1 |
| Matsumoto, S | 1 |
| Takakusagi, Y | 1 |
| Matsuo, M | 1 |
| Morris, HD | 1 |
| Lizak, MJ | 1 |
| Munasinghe, JP | 1 |
| Devasahayam, N | 1 |
| Subramanian, S | 1 |
| Mitchell, JB | 1 |
| Krishna, MC | 1 |
| Wang, TY | 1 |
| Choe, JW | 1 |
| Pu, K | 1 |
| Devulapally, R | 1 |
| Bachawal, S | 1 |
| Machtaler, S | 1 |
| Chowdhury, SM | 1 |
| Luong, R | 1 |
| Tian, L | 1 |
| Khuri-Yakub, B | 1 |
| Rao, J | 1 |
| Paulmurugan, R | 1 |
| Willmann, JK | 1 |
| Waghela, BN | 1 |
| Sharma, A | 1 |
| Dhumale, S | 1 |
| Pandey, SM | 1 |
| Pathak, C | 1 |
| Klippstein, R | 1 |
| Wang, JT | 1 |
| El-Gogary, RI | 1 |
| Bai, J | 1 |
| Mustafa, F | 1 |
| Rubio, N | 1 |
| Bansal, S | 1 |
| Al-Jamal, WT | 1 |
| Al-Jamal, KT | 1 |
| Xiao, B | 1 |
| Han, MK | 1 |
| Viennois, E | 1 |
| Wang, L | 1 |
| Zhang, M | 1 |
| Si, X | 1 |
| Merlin, D | 1 |
| Qin, Y | 1 |
| Cheng, C | 1 |
| Lu, H | 1 |
| Ideno, M | 1 |
| Sasaki, S | 1 |
| Kobayashi, M | 1 |
| Futagi, Y | 1 |
| Narumi, K | 1 |
| Iseki, K | 1 |
| Svenson, S | 1 |
| Case, RI | 1 |
| Cole, RO | 1 |
| Hwang, J | 1 |
| Kabir, SR | 1 |
| Lazarus, D | 1 |
| Lim Soo, P | 1 |
| Ng, PS | 1 |
| Peters, C | 1 |
| Shum, P | 1 |
| Sweryda-Krawiec, B | 1 |
| Tripathi, S | 1 |
| van der Poll, D | 1 |
| Eliasof, S | 1 |
| Del Carmen, S | 1 |
| de Moreno de LeBlanc, A | 1 |
| LeBlanc, JG | 1 |
| Cho, YS | 1 |
| Lee, JH | 1 |
| Jung, KH | 1 |
| Park, JW | 1 |
| Moon, SH | 1 |
| Choe, YS | 1 |
| Lee, KH | 1 |
| Liang, G | 1 |
| Zhu, Y | 1 |
| Jing, A | 1 |
| Wang, J | 4 |
| Hu, F | 1 |
| Feng, W | 1 |
| Xiao, Z | 1 |
| Chen, B | 1 |
| Graboń, W | 1 |
| Otto-Ślusarczyk, D | 1 |
| Chrzanowska, A | 1 |
| Mielczarek-Puta, M | 1 |
| Joniec-Maciejak, I | 1 |
| Słabik, K | 1 |
| Barańczyk-Kuźma, A | 1 |
| Ullmann, P | 1 |
| Qureshi-Baig, K | 1 |
| Rodriguez, F | 1 |
| Ginolhac, A | 1 |
| Nonnenmacher, Y | 1 |
| Ternes, D | 1 |
| Weiler, J | 1 |
| Gäbler, K | 1 |
| Bahlawane, C | 1 |
| Hiller, K | 1 |
| Haan, S | 1 |
| Letellier, E | 1 |
| Manerba, M | 1 |
| Di Ianni, L | 1 |
| Govoni, M | 1 |
| Roberti, M | 1 |
| Recanatini, M | 1 |
| Di Stefano, G | 1 |
| Park, GB | 1 |
| Kim, D | 1 |
| Häggblad Sahlberg, S | 1 |
| Mortensen, AC | 1 |
| Haglöf, J | 1 |
| Engskog, MK | 1 |
| Arvidsson, T | 1 |
| Pettersson, C | 1 |
| Glimelius, B | 1 |
| Stenerlöw, B | 1 |
| Nestor, M | 1 |
| Audet-Delage, Y | 1 |
| Rouleau, M | 2 |
| Roberge, J | 1 |
| Miard, S | 1 |
| Picard, F | 1 |
| Têtu, B | 1 |
| Guillemette, C | 1 |
| Thangaraju, M | 1 |
| Carswell, KN | 1 |
| Prasad, PD | 1 |
| Ganapathy, V | 1 |
| Hu, Z | 1 |
| Pan, Y | 1 |
| Chen, J | 1 |
| Ren, L | 1 |
| Xu, X | 1 |
| Zur Hausen, A | 1 |
| Coy, JF | 1 |
| Löchelt, M | 1 |
| Kanthamneni, N | 1 |
| Chaudhary, A | 2 |
| Prabhu, S | 2 |
| Cui, FY | 1 |
| Song, XR | 1 |
| Li, ZY | 1 |
| Li, SZ | 1 |
| Mu, B | 1 |
| Mao, YQ | 1 |
| Wei, YQ | 1 |
| Yang, L | 1 |
| Wang, C | 1 |
| Ho, PC | 1 |
| Lim, LY | 1 |
| Kim, TH | 1 |
| Jiang, HH | 1 |
| Park, CW | 1 |
| Youn, YS | 1 |
| Lee, S | 1 |
| Chen, X | 1 |
| Lee, KC | 1 |
| Löw, K | 1 |
| Knobloch, T | 1 |
| Wagner, S | 1 |
| Wiehe, A | 1 |
| Engel, A | 1 |
| Langer, K | 1 |
| von Briesen, H | 1 |
| Sutaria, D | 1 |
| Mauro, C | 1 |
| Leow, SC | 1 |
| Anso, E | 1 |
| Rocha, S | 1 |
| Thotakura, AK | 1 |
| Tornatore, L | 1 |
| Moretti, M | 1 |
| De Smaele, E | 1 |
| Beg, AA | 1 |
| Tergaonkar, V | 1 |
| Chandel, NS | 1 |
| Franzoso, G | 1 |
| Jeong, YI | 1 |
| Kim, DH | 1 |
| Chung, CW | 1 |
| Yoo, JJ | 1 |
| Choi, KH | 1 |
| Kim, CH | 1 |
| Ha, SH | 1 |
| Kang, DH | 1 |
| Mendoza-Juez, B | 1 |
| Martínez-González, A | 1 |
| Calvo, GF | 1 |
| Pérez-García, VM | 1 |
| Şengel-Türk, CT | 1 |
| Hasçiçek, C | 1 |
| Dogan, AL | 1 |
| Esendagli, G | 1 |
| Guc, D | 1 |
| Gönül, N | 1 |
| Fuchs, K | 1 |
| Kukuk, D | 1 |
| Reischl, G | 1 |
| Föller, M | 1 |
| Eichner, M | 1 |
| Reutershan, J | 1 |
| Lang, F | 1 |
| Röcken, M | 1 |
| Pichler, BJ | 1 |
| Kneilling, M | 1 |
| Dauchy, RT | 1 |
| Dauchy, EM | 1 |
| Mao, L | 1 |
| Belancio, VP | 1 |
| Hill, SM | 1 |
| Blask, DE | 1 |
| Zhang, JZ | 1 |
| Bryce, NS | 1 |
| Siegele, R | 1 |
| Carter, EA | 1 |
| Paterson, D | 1 |
| de Jonge, MD | 1 |
| Howard, DL | 1 |
| Ryan, CG | 1 |
| Hambley, TW | 1 |
| Araki, T | 1 |
| Kono, Y | 1 |
| Ogawara, K | 1 |
| Watanabe, T | 1 |
| Ono, T | 1 |
| Kimura, T | 1 |
| Higaki, K | 1 |
| Zsivkovits, M | 1 |
| Fekadu, K | 1 |
| Sontag, G | 1 |
| Nabinger, U | 1 |
| Huber, WW | 1 |
| Kundi, M | 1 |
| Chakraborty, A | 1 |
| Foissy, H | 1 |
| Knasmüller, S | 1 |
| Alrefai, WA | 1 |
| Tyagi, S | 1 |
| Gill, R | 1 |
| Saksena, S | 1 |
| Hadjiagapiou, C | 1 |
| Mansour, F | 1 |
| Ramaswamy, K | 1 |
| Dudeja, PK | 1 |
| Jansson, K | 1 |
| Ungerstedt, J | 1 |
| Jonsson, T | 1 |
| Redler, B | 1 |
| Andersson, M | 1 |
| Ungerstedt, U | 1 |
| Norgren, L | 1 |
| Raju, J | 1 |
| Bird, RP | 1 |
| Coady, MJ | 1 |
| Chang, MH | 1 |
| Charron, FM | 1 |
| Plata, C | 1 |
| Wallendorff, B | 1 |
| Sah, JF | 1 |
| Markowitz, SD | 1 |
| Romero, MF | 1 |
| Lapointe, JY | 1 |
| Wenzel, U | 2 |
| Schoberl, K | 1 |
| Lohner, K | 1 |
| Daniel, H | 2 |
| Nickel, A | 1 |
| Rafter, JJ | 1 |
| Hove, H | 2 |
| Rye Clausen, M | 1 |
| Brøbech Mortensen, P | 1 |
| Marteau, P | 1 |
| Rambaud, JC | 1 |
| Singh, J | 1 |
| Rivenson, A | 1 |
| Tomita, M | 1 |
| Shimamura, S | 1 |
| Ishibashi, N | 1 |
| Reddy, BS | 1 |
| Hagiwara, A | 1 |
| Sakakura, C | 1 |
| Shirasu, M | 1 |
| Yamasaki, J | 1 |
| Togawa, T | 1 |
| Takahashi, T | 1 |
| Muranishi, S | 1 |
| Hyon, S | 1 |
| Ikada, Y | 1 |
| Zhang, J | 1 |
| Wu, G | 1 |
| Chapkin, RS | 1 |
| Lupton, JR | 1 |
| Adrian, TE | 1 |
| Fanciulli, M | 1 |
| Bruno, T | 1 |
| Giovannelli, A | 1 |
| Gentile, FP | 1 |
| Di Padova, M | 1 |
| Rubiu, O | 1 |
| Floridi, A | 1 |
| Kaplan, O | 1 |
| Parnaud, G | 1 |
| Corpet, DE | 1 |
| Gamet-Payrastre, L | 1 |
| Fadden, K | 1 |
| Owen, RW | 1 |
| Wargovich, MJ | 1 |
| Allnutt, D | 1 |
| Palmer, C | 1 |
| Anaya, P | 1 |
| Stephens, LC | 1 |
| Lyon, RC | 1 |
| Tschudin, RG | 1 |
| Daly, PF | 1 |
| Cohen, JS | 1 |
| Mueller-Klieser, W | 1 |
| Walenta, S | 1 |
| Paschen, W | 1 |
| Kallinowski, F | 1 |
| Vaupel, P | 1 |
| Vernia, P | 1 |
| Latella, G | 1 |
| Magliocca, FM | 1 |
| Caprilli, R | 1 |
| Tisdale, MJ | 1 |
| Brennan, RA | 1 |
3 reviews available for lactic acid and Colonic Neoplasms
| Article | Year |
|---|---|
The role of lactic acid bacteria in colon cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Bifidobacterium; Colonic Neoplasms; Food Microbiology; Humans; Lac | 1995 |
Potential of using lactic acid bacteria for therapy and immunomodulation in man.
Topics: Colonic Neoplasms; Female; Female Urogenital Diseases; Gram-Positive Bacteria; Humans; Hypercholeste | 1993 |
Lactate and short chain fatty acid production in the human colon: implications for D-lactic acidosis, short-bowel syndrome, antibiotic-associated diarrhoea, colonic cancer, and inflammatory bowel disease.
Topics: Acidosis, Lactic; Animals; Colon; Colonic Neoplasms; Diarrhea; Fatty Acids, Volatile; Humans; Intest | 1998 |
89 other studies available for lactic acid and Colonic Neoplasms
| Article | Year |
|---|---|
Synthesis, physicochemical characterization, and in vitro evaluation of biodegradable PLGA nanoparticles entrapped to folic acid for targeted delivery of kaempferitrin.
Topics: Adenocarcinoma; Colonic Neoplasms; Drug Carriers; Folic Acid; Humans; Lactic Acid; Nanoparticles; Pa | 2022 |
Effect of a Diet Supplemented with Sphingomyelin and Probiotics on Colon Cancer Development in Mice.
Topics: Animals; Colonic Neoplasms; Diet; Lactic Acid; Mice; Probiotics; Sphingomyelins | 2022 |
Far upstream element -binding protein 1 (FUBP1) participates in the malignant process and glycolysis of colon cancer cells by combining with c-Myc.
Topics: Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA-Binding Proteins; Gene Expression Regul | 2022 |
CD44 targeted delivery of hyaluronic acid-coated polymeric nanoparticles against colorectal cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Carriers; Hyaluronic Acid; | 2023 |
Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria.
Topics: Aspartic Acid; Colonic Neoplasms; HCT116 Cells; Homeostasis; Humans; Lactic Acid; Malates; Mitochond | 2020 |
uPAR Knockout Results in a Deep Glycolytic and OXPHOS Reprogramming in Melanoma and Colon Carcinoma Cell Lines.
Topics: Base Sequence; Cell Line, Tumor; Cell Respiration; Colonic Neoplasms; CRISPR-Associated Protein 9; D | 2020 |
IC261, a specific inhibitor of CK1δ/ε, promotes aerobic glycolysis through p53-dependent mechanisms in colon cancer.
Topics: Apoptosis; Blotting, Western; Casein Kinase 1 epsilon; Casein Kinase Idelta; Cell Line, Tumor; Cell | 2020 |
Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells.
Topics: Acidosis, Lactic; Angiogenesis Inhibitors; Apoptosis; Colonic Neoplasms; Diamines; Drug Resistance, | 2020 |
Inhibition of Tumor Progression through the Coupling of Bacterial Respiration with Tumor Metabolism.
Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Humans; Hydrogen Peroxide; Hypoxia-In | 2020 |
A novel miR-206/hnRNPA1/PKM2 axis reshapes the Warburg effect to suppress colon cancer growth.
Topics: Alternative Splicing; Carrier Proteins; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Exp | 2020 |
Codelivery of BV6 and anti-IL6 siRNA by hyaluronate-conjugated PEG-chitosan-lactate nanoparticles inhibits tumor progression.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chick Embryo; Chitosan; Colonic | 2020 |
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Topics: Animals; Antineoplastic Agents; Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Clotri | 2021 |
Topics: Animals; Antineoplastic Agents; Candida tropicalis; Cell Line, Tumor; Colonic Neoplasms; DNA Mismatc | 2021 |
Development of Surface-Variable Polymeric Nanoparticles for Drug Delivery to Tumors.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Carriers; D | 2017 |
Chitosan-modified PLGA nanoparticles tagged with 5TR1 aptamer for in vivo tumor-targeted drug delivery.
Topics: Adsorption; Animals; Antibiotics, Antineoplastic; Aptamers, Nucleotide; Cell Survival; Chitosan; CHO | 2017 |
Interleukin-22 promotes aerobic glycolysis associated with tumor progression via targeting hexokinase-2 in human colon cancer cells.
Topics: Aerobiosis; Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Progression; G | 2017 |
Development of biomedical 5-fluorouracil nanoplatforms for colon cancer chemotherapy: Influence of process and formulation parameters.
Topics: Cell Line, Tumor; Colonic Neoplasms; Drug Carriers; Fluorouracil; Humans; Lactic Acid; Nanoparticles | 2017 |
Antitumor Efficacy and Toxicity of 5-Fluorouracil-Loaded Poly(Lactide Co-glycolide) Pellets.
Topics: Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Delayed-Action Preparations; Drug Carri | 2018 |
In vitro activities of inulin fermentation products to HCT-116 cells enhanced by the cooperation between exogenous strains and adult faecal microbiota.
Topics: Acetates; Apoptosis; Butyric Acid; Colonic Neoplasms; DNA Fragmentation; Enterococcus; Feces; Fermen | 2018 |
Protein kinase CK2 modulation of pyruvate kinase M isoforms augments the Warburg effect in cancer cells.
Topics: Casein Kinase II; Cell Proliferation; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Gene Exp | 2018 |
Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome.
Topics: Amino Acid Transport System ASC; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neopla | 2019 |
Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.
Topics: Animals; Carcinogenesis; Cell Line, Tumor; Cluster Analysis; Colonic Neoplasms; Disease Models, Anim | 2013 |
Local antitumor effects of intratumoral delivery of rlL-2 loaded sustained-release dextran/PLGA-PLA core/shell microspheres.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Delayed-Action Preparations; De | 2013 |
Hemostatic absorbable gelatin sponge loaded with 5-fluorouracil for treatment of tumors.
Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Delayed-Action Pr | 2013 |
Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study.
Topics: Adenocarcinoma; Antineoplastic Agents; Citric Acid Cycle; Colonic Neoplasms; Glucose; Glycolysis; Hi | 2014 |
Targeted delivery of 5-fluorouracil to HT-29 cells using high efficient folic acid-conjugated nanoparticles.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Biological Transport; Cell Survival; Colonic Neopla | 2015 |
Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gas Chromatography-Mass Spectrometry; | 2014 |
miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway.
Topics: Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; | 2014 |
Feasibility of multianimal hyperpolarized (13) C MRS.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Colonic Neoplasms; Cost-Benefit Analysis; Energy | 2015 |
A new magnetic nanocapsule containing 5-fluorouracil: in vivo drug release, anti-tumor, and pro-apoptotic effects on CT26 cells allograft model.
Topics: Allografts; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Delayed- | 2014 |
Engineering of near infrared fluorescent proteinoid-poly(L-lactic acid) particles for in vivo colon cancer detection.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Line, Tumor; Chick Embryo; Colonic N | 2014 |
Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11β-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Colo | 2014 |
Synthesis and characterization of bioactive conjugated near-infrared fluorescent proteinoid-poly(L-lactic acid) hollow nanoparticles for optical detection of colon cancer.
Topics: Animals; Carcinoembryonic Antigen; Cell Line, Tumor; Cell Survival; Chick Embryo; Chickens; Chorioal | 2014 |
Multi-modal detection of colon malignancy by NIR-tagged recognition polymers and ultrasound contrast agents.
Topics: Acoustics; Acrylic Resins; Animals; Cell Line; Cell Line, Tumor; Cell Survival; Colon; Colonic Neopl | 2015 |
13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors.
Topics: Animals; Carbon Isotopes; Carcinoma, Squamous Cell; Colonic Neoplasms; HT29 Cells; Humans; Lactic Ac | 2015 |
Ultrasound-guided delivery of microRNA loaded nanoparticles into cancer.
Topics: Animals; Cell Line, Tumor; Colon; Colonic Neoplasms; Drug Delivery Systems; Equipment Design; Humans | 2015 |
Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Availability; Biological Transport; Cell Line, | 2015 |
Passively Targeted Curcumin-Loaded PEGylated PLGA Nanocapsules for Colon Cancer Therapy In Vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Curcumin; Drug Carri | 2015 |
Hyaluronic acid-functionalized polymeric nanoparticles for colon cancer-targeted combination chemotherapy.
Topics: Animals; Caco-2 Cells; Camptothecin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Curcumin; D | 2015 |
miR-4458 suppresses glycolysis and lactate production by directly targeting hexokinase2 in colon cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Genes, Tumor Suppressor; Glucose; Glycolysis; Hexokinase; Human | 2016 |
Influence of high glucose state on bromopyruvate-induced cytotoxity by human colon cancer cell lines.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Down-Regulati | 2016 |
Tumor Selective Silencing Using an RNAi-Conjugated Polymeric Nanopharmaceutical.
Topics: Animals; Chemistry, Pharmaceutical; Colonic Neoplasms; Female; Gene Silencing; Genetic Therapy; Gree | 2016 |
Development of a potential probiotic yoghurt using selected anti-inflammatory lactic acid bacteria for prevention of colitis and carcinogenesis in mice.
Topics: Animals; Carcinogenesis; Colitis; Colonic Neoplasms; Female; Fermentation; Humans; Intestines; Lacti | 2016 |
Molecular mechanism of (18)F-FDG uptake reduction induced by genipin in T47D cancer cell and role of uncoupling protein-2 in cancer cell glucose metabolism.
Topics: Biological Transport; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relations | 2016 |
Cationic microRNA-delivering nanocarriers for efficient treatment of colon carcinoma in xenograft model.
Topics: Animals; Apoptosis; Carcinoma; Colonic Neoplasms; G1 Phase Cell Cycle Checkpoints; Genetic Vectors; | 2016 |
Lactate Formation in Primary and Metastatic Colon Cancer Cells at Hypoxia and Normoxia.
Topics: Aspartate Aminotransferases; Aspartic Acid; Cell Count; Cell Hypoxia; Cell Line, Tumor; Colonic Neop | 2016 |
Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production.
Topics: Aged; Aged, 80 and over; Carcinogenesis; Cell Self Renewal; Colon; Colonic Neoplasms; Colorectal Neo | 2016 |
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.
Topics: Caco-2 Cells; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Humans; Inflammation; Interleuki | 2017 |
TLR4-mediated galectin-1 production triggers epithelial-mesenchymal transition in colon cancer cells through ADAM10- and ADAM17-associated lactate production.
Topics: ADAM10 Protein; ADAM17 Protein; Amyloid Precursor Protein Secretases; Cell Line, Tumor; Colonic Neop | 2017 |
Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.
Topics: Alanine; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Fatty Ac | 2017 |
Cross-Talk between Alternatively Spliced UGT1A Isoforms and Colon Cancer Cell Metabolism.
Topics: Alternative Splicing; Carrier Proteins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Prolife | 2017 |
Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.
Topics: Adult; Apoptosis; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; Flow Cyt | 2009 |
Meso-tetra (carboxyphenyl) porphyrin (TCPP) nanoparticles were internalized by SW480 cells by a clathrin-mediated endocytosis pathway to induce high photocytotoxicity.
Topics: Blotting, Western; Cell Line, Tumor; Clathrin Heavy Chains; Colonic Neoplasms; Endocytosis; Gene Exp | 2009 |
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells.
Topics: Adenosine Triphosphate; Apoptosis; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; DNA | 2009 |
Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Calcium; Cell Line, Tumor; | 2010 |
The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma.
Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dependovirus | 2010 |
Wheat germ agglutinin-conjugated PLGA nanoparticles for enhanced intracellular delivery of paclitaxel to colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Cell Line, Tumor; Cell Proliferation; Chemi | 2010 |
PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Delayed-Action Preparations; HCT116 Cells; Humans | 2011 |
Comparison of intracellular accumulation and cytotoxicity of free mTHPC and mTHPC-loaded PLGA nanoparticles in human colon carcinoma cells.
Topics: Bromodeoxyuridine; Cell Death; Cell Membrane; Cell Proliferation; Cell Survival; Chemical Phenomena; | 2011 |
Chemoprevention of colon cancer in a rat carcinogenesis model using a novel nanotechnology-based combined treatment system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; As | 2011 |
NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; bcl-2 Homologous Antagonist-Killer Prote | 2011 |
Self-assembled nanoparticles of hyaluronic acid/poly(DL-lactide-co-glycolide) block copolymer.
Topics: Antineoplastic Agents; Binding, Competitive; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Delayed | 2012 |
A mathematical model for the glucose-lactate metabolism of in vitro cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Energy Metabolism; Female; Glioma; Glucose; Humans; Lactic Acid | 2012 |
Preparation and in vitro evaluation of meloxicam-loaded PLGA nanoparticles on HT-29 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Biological Transport; Cell Survival; Chemistry, Pharmaceutica | 2012 |
Oxygen breathing affects 3'-deoxy-3'-18F-fluorothymidine uptake in mouse models of arthritis and cancer.
Topics: Anesthesia; Animals; Ankle; Arthritis; Artifacts; Biological Transport; Carbon Dioxide; Cell Line, T | 2012 |
A new apparatus and surgical technique for the dual perfusion of human tumor xenografts in situ in nude rats.
Topics: Adenocarcinoma; Animals; Artificial Organs; Blood Glucose; Carbon Dioxide; Cell Proliferation; Colon | 2012 |
The use of spectroscopic imaging and mapping techniques in the characterisation and study of DLD-1 cell spheroid tumour models.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Humans; Lactic Acid; Microsco | 2012 |
Formulation and evaluation of paclitaxel-loaded polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colonic N | 2012 |
Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains.
Topics: Amines; Animals; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; Lactic Acid; Lactobacillus; | 2003 |
Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate.
Topics: Adenocarcinoma; Butyric Acid; Caco-2 Cells; Carcinogens; Colonic Neoplasms; Drug Administration Sche | 2004 |
Human intraperitoneal microdialysis: increased lactate/pyruvate ratio suggests early visceral ischaemia. A pilot study.
Topics: Aged; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Intestines; Ischemia; Lactic Acid; Male; | 2003 |
Energy restriction reduces the number of advanced aberrant crypt foci and attenuates the expression of colonic transforming growth factor beta and cyclooxygenase isoforms in Zucker obese (fa/fa) rats.
Topics: Animals; Azoxymethane; Blood Glucose; Body Weight; Caloric Restriction; Carcinogens; Colonic Neoplas | 2003 |
The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter.
Topics: Animals; Carboxylic Acids; Cation Transport Proteins; Cell Membrane; Colon; Colonic Neoplasms; Cyclo | 2004 |
Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells.
Topics: Apoptosis; Biological Transport; Citric Acid; Colonic Neoplasms; Contrast Media; Flavones; Flavonoid | 2005 |
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
Topics: Angiogenesis Inhibitors; Apoptosis; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytosol; DNA | 2005 |
Lactate and pH in faeces from patients with colonic adenomas or cancer.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Animals; Colonic Neoplasms; Dietary Carbohydrates; Dietary | 1993 |
Bifidobacterium longum, a lactic acid-producing intestinal bacterium inhibits colon cancer and modulates the intermediate biomarkers of colon carcinogenesis.
Topics: Animals; Bifidobacterium; Biomarkers, Tumor; Blotting, Western; Cell Division; Colonic Neoplasms; La | 1997 |
Therapeutic effects of 5-fluorouracil microspheres on peritoneal carcinomatosis induced by Colon 26 or B-16 melanoma in mice.
Topics: Animals; Biocompatible Materials; Colonic Neoplasms; Fluorouracil; Injections, Intraperitoneal; Lact | 1998 |
Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen.
Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Butyrates; Butyric Acid; Carcinogens; Cellulose; Colon | 1998 |
A factor from pancreatic and colonic cancer cells stimulates glucose uptake and lactate production in myoblasts.
Topics: Animals; Biological Factors; Cell Line; Colonic Neoplasms; Culture Media, Conditioned; Cycloheximide | 1999 |
Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence of lonidamine.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Carbon Dioxide; Cell Division; Citrate (si)-Synthase; | 2000 |
Correspondence re: M. Fanciulli et al., Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence fo lonidamine. Clin. Cancer Res., 6: 1590-1597, 2000.
Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Neoplasm; Glycolysis; Hexokinase; Humans; | 2000 |
Cytostatic effect of polyethylene glycol on human colonic adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Differentiation; Cell Division; | 2001 |
Faecal steroids and colorectal cancer: the effect of lactulose on faecal bacterial metabolism in a continuous culture model of the large intestine.
Topics: Amino Acids; Bacteria; Bile Acids and Salts; Biomarkers, Tumor; Chenodeoxycholic Acid; Colon; Coloni | 1992 |
Inhibition of the promotional phase of azoxymethane-induced colon carcinogenesis in the F344 rat by calcium lactate: effect of simulating two human nutrient density levels.
Topics: Animals; Azo Compounds; Azoxymethane; Calcium; Calcium, Dietary; Colonic Neoplasms; Dietary Fats; Di | 1990 |
A versatile multinuclear probe designed for in vivo NMR spectroscopy: applications to subcutaneous human tumors in mice.
Topics: Animals; Breast Neoplasms; Colonic Neoplasms; Glucose; Humans; In Vitro Techniques; Infant, Newborn; | 1988 |
Metabolic imaging in microregions of tumors and normal tissues with bioluminescence and photon counting.
Topics: Adenosine Triphosphate; Animals; Colonic Neoplasms; Female; Glucose; Humans; Lactates; Lactic Acid; | 1988 |
Fecal organic anions in diarrhoeal diseases.
Topics: Colitis, Ulcerative; Colonic Diseases, Functional; Colonic Neoplasms; Crohn Disease; Diarrhea; Fatty | 1987 |
Metabolic substrate utilization by a tumour cell line which induces cachexia in vivo.
Topics: Adenocarcinoma; Animals; Cachexia; Cell Line; Colonic Neoplasms; Glucose; Ketone Bodies; Lactates; L | 1986 |