lactic acid has been researched along with Colitis Gravis in 18 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 normals." | 3.67 | Organic anions and the diarrhea of inflammatory bowel disease. ( Breuer, RI; Gnaedinger, A; Hauck, W; Vernia, P, 1988) |
| "An acetic acid (AA)-induced ulcerative colitis rat model was applied in the study." | 1.40 | The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action. ( Jia, W; Lu, H; Ma, C; Qiu, M; Sun, W; Wu, H; Xin, X; Yang, Y; Zhao, A; Zhao, L; Zou, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, S | 1 |
| Xu, X | 1 |
| Liang, L | 1 |
| Wang, X | 1 |
| Bai, X | 1 |
| Zhu, L | 1 |
| He, Q | 1 |
| Liang, H | 1 |
| Xin, X | 2 |
| Wang, L | 1 |
| Lou, C | 1 |
| Cao, X | 1 |
| Chen, X | 1 |
| Li, B | 1 |
| Wang, B | 1 |
| Zhao, J | 1 |
| Zhang, Q | 1 |
| Gao, X | 1 |
| Wu, J | 1 |
| Chen, M | 1 |
| Liu, S | 1 |
| Yan, W | 1 |
| Lv, Q | 1 |
| Yang, L | 1 |
| Miao, Y | 1 |
| Hu, Y | 1 |
| Wei, Z | 1 |
| Meng, X | 1 |
| Dunsmore, G | 1 |
| Koleva, P | 1 |
| Elloumi, Y | 1 |
| Wu, RY | 1 |
| Sutton, RT | 1 |
| Ambrosio, L | 1 |
| Hotte, N | 1 |
| Nguyen, V | 1 |
| Madsen, KL | 1 |
| Dieleman, LA | 1 |
| Chen, H | 1 |
| Huang, V | 1 |
| Elahi, S | 1 |
| Machiels, K | 1 |
| Joossens, M | 1 |
| Sabino, J | 1 |
| De Preter, V | 1 |
| Arijs, I | 1 |
| Eeckhaut, V | 1 |
| Ballet, V | 1 |
| Claes, K | 1 |
| Van Immerseel, F | 1 |
| Verbeke, K | 1 |
| Ferrante, M | 1 |
| Verhaegen, J | 1 |
| Rutgeerts, P | 1 |
| Vermeire, S | 1 |
| Lautenschläger, C | 1 |
| Schmidt, C | 1 |
| Lehr, CM | 1 |
| Fischer, D | 1 |
| Stallmach, A | 1 |
| Zhao, L | 1 |
| Wu, H | 1 |
| Zhao, A | 1 |
| Lu, H | 1 |
| Sun, W | 1 |
| Ma, C | 1 |
| Yang, Y | 1 |
| Zou, H | 1 |
| Qiu, M | 1 |
| Jia, W | 1 |
| Xiao, B | 2 |
| Si, X | 1 |
| Zhang, M | 2 |
| Merlin, D | 2 |
| Zhang, Z | 1 |
| Viennois, E | 1 |
| Kang, Y | 1 |
| Han, MK | 1 |
| Chen, J | 1 |
| Vigsnaes, LK | 1 |
| van den Abbeele, P | 1 |
| Sulek, K | 1 |
| Frandsen, HL | 1 |
| Steenholdt, C | 1 |
| Brynskov, J | 1 |
| Vermeiren, J | 1 |
| van de Wiele, T | 1 |
| Licht, TR | 1 |
| van Nuenen, MH | 1 |
| Venema, K | 1 |
| van der Woude, JC | 1 |
| Kuipers, EJ | 1 |
| Treem, WR | 1 |
| Ahsan, N | 1 |
| Shoup, M | 1 |
| Hyams, JS | 1 |
| Ahmad, MS | 1 |
| Krishnan, S | 1 |
| Ramakrishna, BS | 1 |
| Mathan, M | 1 |
| Pulimood, AB | 1 |
| Murthy, SN | 1 |
| Bianchi-Salvadori, B | 1 |
| Vesely, R | 1 |
| Ferrari, A | 1 |
| Canzi, E | 1 |
| Casiraghi, C | 1 |
| Brighenti, F | 1 |
| D'Argenio, G | 1 |
| Sorrentini, I | 1 |
| Cosenza, V | 1 |
| Gatto, A | 1 |
| Iovino, P | 1 |
| D'Armiento, EP | 1 |
| Baldassarre, F | 1 |
| Mazzacca, G | 1 |
| Vernia, P | 3 |
| Gnaedinger, A | 1 |
| Hauck, W | 1 |
| Breuer, RI | 1 |
| Caprilli, R | 2 |
| Latella, G | 2 |
| Barbetti, F | 1 |
| Magliocca, FM | 2 |
| Cittadini, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tolerability and Risk of Adverse Events With a Probiotic Supplement: A Randomised and Placebo Controlled Study in Healthy Individuals[NCT03728868] | 50 participants (Actual) | Interventional | 2018-10-10 | Completed | |||
| PediCRaFT: Pediatric Crohn's Disease Fecal Microbiota Transplant Pilot Study[NCT03378167] | Phase 1 | 17 participants (Actual) | Interventional | 2018-12-01 | Completed | ||
| Multi-center Clinical Research About Standard Diagnosis and Treatment of Neonate Severe Digestive System Malformation[NCT02699320] | 33 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lactic acid and Colitis Gravis
| Article | Year |
|---|---|
PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease.
Topics: Administration, Oral; Adult; Case-Control Studies; Chitosan; Colitis, Ulcerative; Crohn Disease; Dru | 2013 |
17 other studies available for lactic acid and Colitis Gravis
| Article | Year |
|---|---|
Lactic Acid-Producing Probiotic
Topics: Animals; Caspase 1; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Dysbiosis; Fatty | 2021 |
The Correlation between Endotoxin, D-Lactate, and Diamine Oxidase with Endoscopic Activity in Inflammatory Bowel Disease.
Topics: Amine Oxidase (Copper-Containing); Biomarkers; C-Reactive Protein; Colitis, Ulcerative; Crohn Diseas | 2022 |
3, 3'-diindolylmethane, a natural aryl hydrocarbon receptor agonist, alleviates ulcerative colitis by enhancing "glycolysis-lactate-STAT3″ and TIP60 signals-mediated Treg differentiation.
Topics: Animals; Cell Differentiation; Colitis; Colitis, Ulcerative; Forkhead Transcription Factors; Glucose | 2023 |
The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn.
Topics: Aminobutyrates; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Case-Control Studies; | 2019 |
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis.
Topics: Adult; Bacterial Load; Butyric Acid; Case-Control Studies; Colitis, Ulcerative; Denaturing Gradient | 2014 |
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis.
Topics: Adult; Bacterial Load; Butyric Acid; Case-Control Studies; Colitis, Ulcerative; Denaturing Gradient | 2014 |
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis.
Topics: Adult; Bacterial Load; Butyric Acid; Case-Control Studies; Colitis, Ulcerative; Denaturing Gradient | 2014 |
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis.
Topics: Adult; Bacterial Load; Butyric Acid; Case-Control Studies; Colitis, Ulcerative; Denaturing Gradient | 2014 |
The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action.
Topics: Acetic Acid; Amine Oxidase (Copper-Containing); Animals; Astragalus propinquus; Colitis, Ulcerative; | 2014 |
Oral administration of pH-sensitive curcumin-loaded microparticles for ulcerative colitis therapy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Curcumi | 2015 |
Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Products; Cell Line; Colitis, Ul | 2016 |
Microbiotas from UC patients display altered metabolism and reduced ability of LAB to colonize mucus.
Topics: Bacteria; Colitis, Ulcerative; Feces; Gastrointestinal Tract; Humans; Intestinal Mucosa; Lactic Acid | 2013 |
The metabolic activity of fecal microbiota from healthy individuals and patients with inflammatory bowel disease.
Topics: Adult; Ammonia; Bacteria; Colitis, Ulcerative; Colon; Crohn Disease; Fatty Acids; Fatty Acids, Volat | 2004 |
Fecal short-chain fatty acids in children with inflammatory bowel disease.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Colitis, Ulcerative; Colon; Crohn Disease; Fatty Acid | 1994 |
Butyrate and glucose metabolism by colonocytes in experimental colitis in mice.
Topics: Animals; Butyrates; Colitis, Ulcerative; Colon; Dextran Sulfate; Glucose; Lactic Acid; Mice; Oxidati | 2000 |
Behaviour of the pharmaceutical probiotic preparation VSL#3 in human ileostomy effluent containing its own natural elements.
Topics: Adult; Bifidobacterium; Bile Acids and Salts; Colitis, Ulcerative; Colony Count, Microbial; Fatty Ac | 2001 |
Serum and tissue transglutaminase correlates with the severity of inflammation in induced colitis in the rat.
Topics: Acute Disease; Animals; Biomarkers; Colitis, Ulcerative; Immunohistochemistry; Lactates; Lactic Acid | 1992 |
Organic anions and the diarrhea of inflammatory bowel disease.
Topics: Anions; Citric Acid Cycle; Colitis, Ulcerative; Crohn Disease; Diarrhea; Fatty Acids, Volatile; Fece | 1988 |
Fecal lactate and ulcerative colitis.
Topics: Colitis, Ulcerative; Fatty Acids, Volatile; Feces; Humans; Hydrogen-Ion Concentration; Lactates; Lac | 1988 |
Fecal organic anions in diarrhoeal diseases.
Topics: Colitis, Ulcerative; Colonic Diseases, Functional; Colonic Neoplasms; Crohn Disease; Diarrhea; Fatty | 1987 |