lactic acid has been researched along with Cognitive Dysfunction in 17 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He was found to have high anion gap metabolic acidosis with significantly elevated lactate along with an elevated osmolal gap and calcium oxalate crystals in his urine." | 3.85 | Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning? ( Abu Sitta, E; Gaddam, M; Kanzy, A; Velagapudi, RK, 2017) |
| "Asystole as the initial arrest rhythm, administration of >4 adrenaline doses, and higher post-arrest blood lactate concentration were independently associated with lower 12-month survival; an adrenaline dosing interval of 3-<5 min and open chest compressions were independently associated with greater 12-month survival." | 2.87 | Paediatric in-hospital cardiac arrest: Factors associated with survival and neurobehavioural outcome one year later. ( Berger, J; Christensen, JR; Dean, JM; Holubkov, R; Meert, K; Moler, FW; Newth, CJL; Ofori-Amanfo, G; Slomine, BS; Telford, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 7 (41.18) | 2.80 |
| Authors | Studies |
|---|---|
| Hiraki, N | 1 |
| Tanaka, TD | 1 |
| Yoshimura, M | 1 |
| Song, Y | 2 |
| Liu, Z | 1 |
| Zhu, X | 1 |
| Hao, C | 1 |
| Hao, W | 1 |
| Wu, S | 1 |
| Yang, J | 1 |
| Lu, X | 1 |
| Jin, C | 1 |
| Zhao, L | 2 |
| Jiang, H | 1 |
| Xie, J | 1 |
| Shen, D | 1 |
| Yi, Q | 1 |
| Yan, J | 1 |
| Li, C | 2 |
| Zheng, H | 2 |
| Gao, H | 2 |
| Cha, H | 1 |
| Choi, JH | 1 |
| Jeon, H | 1 |
| Kim, JH | 2 |
| Kim, M | 1 |
| Kim, SJ | 1 |
| Park, W | 1 |
| Lim, JS | 1 |
| Lee, E | 1 |
| Ahn, JS | 1 |
| Hong, SH | 1 |
| Park, JE | 1 |
| Jung, JH | 1 |
| Yoo, HJ | 1 |
| Lee, S | 2 |
| Singh, V | 1 |
| Mishra, VN | 1 |
| Prajapati, GD | 1 |
| Ampapathi, RS | 1 |
| Thakur, MK | 1 |
| Shan, B | 1 |
| Ai, Z | 1 |
| Zeng, S | 1 |
| Song, J | 1 |
| Zeng, Q | 1 |
| Liao, Z | 1 |
| Wang, T | 1 |
| Huang, C | 1 |
| Su, D | 1 |
| Netzahualcoyotzi, C | 1 |
| Pellerin, L | 1 |
| Liguori, C | 1 |
| Mercuri, NB | 1 |
| Izzi, F | 1 |
| Romigi, A | 1 |
| Cordella, A | 1 |
| Sancesario, G | 1 |
| Placidi, F | 1 |
| Rooijackers, HM | 1 |
| Wiegers, EC | 1 |
| van der Graaf, M | 1 |
| Thijssen, DH | 1 |
| Kessels, RPC | 1 |
| Tack, CJ | 1 |
| de Galan, BE | 1 |
| Gaddam, M | 1 |
| Velagapudi, RK | 1 |
| Abu Sitta, E | 1 |
| Kanzy, A | 1 |
| Meert, K | 1 |
| Telford, R | 1 |
| Holubkov, R | 1 |
| Slomine, BS | 1 |
| Christensen, JR | 1 |
| Berger, J | 1 |
| Ofori-Amanfo, G | 1 |
| Newth, CJL | 1 |
| Dean, JM | 1 |
| Moler, FW | 1 |
| Chen, K | 1 |
| Sun, Y | 1 |
| Dong, W | 1 |
| Zhang, T | 1 |
| Zhou, N | 1 |
| Yu, W | 1 |
| Diao, Y | 1 |
| Guo, S | 1 |
| Tian, Y | 1 |
| Dong, M | 1 |
| Ren, M | 2 |
| Choi, YS | 1 |
| Kang, S | 1 |
| Ko, SY | 1 |
| Kim, JY | 1 |
| Lee, H | 1 |
| Song, JE | 1 |
| Kim, DH | 1 |
| Kim, E | 1 |
| Kim, CH | 1 |
| Saksida, L | 1 |
| Song, HT | 1 |
| Lee, JE | 1 |
| Pan, H | 1 |
| Huang, X | 1 |
| Li, F | 1 |
| Zhang, J | 1 |
| Xu, M | 1 |
| Wu, M | 1 |
| Tang, X | 1 |
| Li, Z | 1 |
| Zhang, W | 1 |
| Yao, Z | 1 |
| Weaver, KE | 1 |
| Richards, TL | 1 |
| Logsdon, RG | 1 |
| McGough, EL | 1 |
| Minoshima, S | 1 |
| Aylward, EH | 1 |
| Kleinhans, NM | 1 |
| Grabowski, TJ | 1 |
| McCurry, SM | 1 |
| Teri, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Exercise-induced Hyperlacticacidemia on Counterregulatory Responses, Symptoms, Cognitive Function and Brain Lactate Accumulation During Hypoglycemia in (Hypoglycemic Unaware)Type I Diabetes Patients and Normal Controls[NCT02308293] | 30 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Cognitive Dysfunction
| Article | Year |
|---|---|
Nitric oxide might be an inducing factor in cognitive impairment in Alzheimer's disease via downregulating the monocarboxylate transporter 1.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Down-Regulation; Humans; Lactic Acid; Monocarboxy | 2019 |
2 trials available for lactic acid and Cognitive Dysfunction
| Article | Year |
|---|---|
A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients With Type 1 Diabetes.
Topics: Adult; Awareness; Case-Control Studies; Catecholamines; Cognitive Dysfunction; Cross-Over Studies; D | 2017 |
Paediatric in-hospital cardiac arrest: Factors associated with survival and neurobehavioural outcome one year later.
Topics: Adolescent; Cardiopulmonary Resuscitation; Child; Child, Preschool; Cognitive Dysfunction; Coma; Epi | 2018 |
14 other studies available for lactic acid and Cognitive Dysfunction
| Article | Year |
|---|---|
A Man With Left Ventricular Hypertrophy.
Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc | 2022 |
Metformin alleviates the cognitive impairment caused by aluminum by improving energy metabolism disorders in mice.
Topics: Aluminum; AMP-Activated Protein Kinases; Animals; Cognitive Dysfunction; Energy Metabolism; Glucose; | 2022 |
Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline.
Topics: Animals; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Fibroblast Growth Factors; Humans; | 2022 |
Aquaporin-4 Deficiency is Associated with Cognitive Impairment and Alterations in astrocyte-neuron Lactate Shuttle.
Topics: Animals; Aquaporin 4; Astrocytes; Cognitive Dysfunction; Glucose; Humans; Lactic Acid; Mice; Mice, K | 2023 |
Quantitative metabolic biomarker analysis of mild cognitive impairment in eastern U.P. and Bihar population.
Topics: Aged; Alanine; Biomarkers; Blood Glucose; Blood Specimen Collection; Choline; Cognitive Dysfunction; | 2020 |
Gut microbiome-derived lactate promotes to anxiety-like behaviors through GPR81 receptor-mediated lipid metabolism pathway.
Topics: Animals; Anxiety; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Gastrointestinal | 2020 |
Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation.
Topics: Animals; Astrocytes; Behavior, Animal; Cognitive Dysfunction; Genetic Vectors; Hippocampus; Lactic A | 2020 |
Obstructive Sleep Apnea is Associated With Early but Possibly Modifiable Alzheimer's Disease Biomarkers Changes.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognition; Cognitive Dysfunction; Contin | 2017 |
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning?
Topics: Acid-Base Equilibrium; Acidosis; Anticonvulsants; Brain Diseases; Calcium Oxalate; Cognitive Dysfunc | 2017 |
Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory Response Through the Th17 Immune Response.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; bcl-2-Associated X Protein; Brain; Cardiopulmonary | 2018 |
Metabolomic Analysis Identifies Lactate as an Important Pathogenic Factor in Diabetes-associated Cognitive Decline Rats.
Topics: Analysis of Variance; Animals; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; C | 2018 |
Hyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet.
Topics: Animals; Blood-Brain Barrier; Brain; Carbon Isotopes; Cognitive Dysfunction; Diet, High-Fat; Disease | 2018 |
Association among plasma lactate, systemic inflammation, and mild cognitive impairment: a community-based study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; C-Reactive Protein; Cognitive Dysfunction; | 2019 |
Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Amnesia; Biomarkers; Cognitive Dysfunction; Female; Gyrus Cinguli; Humans; | 2015 |