lactic acid has been researched along with Chronic Pain in 8 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the CPIP acute phase, we observed mechanical and cold allodynia; increased levels of tumor necrosis factor-α (hind paw), ischemia-modified albumin (IMA) (serum), protein carbonyl (hind paw and spinal cord), lactate (serum), and 4-hydroxy-2-nonenal (4-HNE, hind paw and spinal cord); and higher myeloperoxidase (MPO) and N-acetyl-β-D-glucosaminidase (NAGase) activities (hind paw)." | 3.83 | Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms. ( Bochi, GV; da Silva, MA; de Prá, SD; Ferreira, J; Klafke, JZ; Moresco, RN; Rigo, FK; Rossato, MF; Trevisan, G; Walker, CI, 2016) |
| "Opioid-induced hyperalgesia (OIH) is one of the major problems associated with prolonged use of opioids for the treatment of chronic pain." | 1.43 | PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα. ( Hu, X; Huang, F; Liu, Y; Szymusiak, M; Tian, X; Wang, ZJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Peng, Y | 1 |
| Zhang, C | 1 |
| Zhou, X | 1 |
| Liu, B | 1 |
| Zhang, D | 1 |
| Tu, H | 1 |
| Alimi, OA | 1 |
| Kong, Y | 1 |
| Satyanarayana, R | 1 |
| Kuss, M | 1 |
| Li, Y | 1 |
| Duan, B | 1 |
| Chen, KK | 1 |
| Hutchinson, MR | 1 |
| Rolan, P | 1 |
| de Zoete, RMJ | 1 |
| Dommerholt, J | 1 |
| Hooks, T | 1 |
| Chou, LW | 1 |
| Finnegan, M | 1 |
| Fernandes, IMC | 1 |
| Morelhão, PK | 1 |
| Hisamatsu, TM | 1 |
| Diniz, TA | 1 |
| Gerosa-Neto, J | 1 |
| Panissa, VLG | 1 |
| Lira, FS | 1 |
| Pinto, RZ | 1 |
| Gerdle, B | 1 |
| Larsson, B | 1 |
| Forsberg, F | 1 |
| Ghafouri, N | 1 |
| Karlsson, L | 1 |
| Stensson, N | 1 |
| Ghafouri, B | 1 |
| Klafke, JZ | 1 |
| da Silva, MA | 1 |
| Rossato, MF | 1 |
| de Prá, SD | 1 |
| Rigo, FK | 1 |
| Walker, CI | 1 |
| Bochi, GV | 1 |
| Moresco, RN | 1 |
| Ferreira, J | 1 |
| Trevisan, G | 1 |
| Hu, X | 1 |
| Huang, F | 1 |
| Szymusiak, M | 1 |
| Tian, X | 1 |
| Liu, Y | 1 |
| Wang, ZJ | 1 |
1 trial available for lactic acid and Chronic Pain
| Article | Year |
|---|---|
Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial.
Topics: Adult; Australia; Central Nervous System Sensitization; Chronic Pain; Cross-Over Studies; Exercise; | 2023 |
7 other studies available for lactic acid and Chronic Pain
| Article | Year |
|---|---|
Astrocyte-neuron lactate transport in the ACC contributes to the occurrence of long-lasting inflammatory pain in male mice.
Topics: Animals; Arabinose; Astrocytes; Cell Communication; Chronic Pain; Disease Models, Animal; Freund's A | 2021 |
Red blood cell membrane-camouflaged poly(lactic-co-glycolic acid) microparticles as a potential controlled release drug delivery system for local stellate ganglion microinjection.
Topics: Animals; Chronic Pain; Delayed-Action Preparations; Drug Delivery Systems; Erythrocytes; Glycols; Hu | 2023 |
Myofascial pain and treatment: Editorial.
Topics: Acupuncture Therapy; Animals; Chronic Pain; Disease Models, Animal; Dry Needling; Female; Glucose; G | 2019 |
Assessment of aerobic fitness in individuals with and without nonspecific chronic low back pain: a pilot study.
Topics: Adult; Body Mass Index; Chronic Pain; Exercise Test; Female; Heart Rate; Humans; Lactic Acid; Low Ba | 2021 |
Chronic widespread pain: increased glutamate and lactate concentrations in the trapezius muscle and plasma.
Topics: Adult; Carbon Isotopes; Catastrophization; Chronic Pain; Female; Glutamic Acid; Health Status; Human | 2014 |
Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms.
Topics: Acetylglucosaminidase; Acute Pain; Aldehydes; Animals; Chronic Pain; Cold Temperature; Hindlimb; Hyp | 2016 |
PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα.
Topics: Analgesics, Opioid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chronic Pain; Curcu | 2016 |