lactic acid has been researched along with Chronic Lung Injury in 18 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bosutinib as an adjunct therapy to a balanced transfusion strategy reduced resuscitation volume, improved shock reversal, and reduced vascular leak and organ injury in a rat polytrauma model." | 4.02 | Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model. ( Aman, J; Botros, L; Hollmann, MW; Juffermans, NP; Kers, J; Kleinveld, DJB; Maas, MAW, 2021) |
| " In both groups, blood samples were collected from the right superior pulmonary vein, and inflammation and oxidative stress markers (malondialdehyde, lactic acid, platelet-activating factor, and myeloperoxidase) were studied." | 3.77 | Does on-pump normothermic beating-heart valve surgery with low tidal volume ventilation protect the lungs? ( Altinay, L; Babaroglu, S; Cicekcioglu, F; Katircioglu, SF; Mungan, U; Parlar, AI; Saydam, GS; Topcu, DI; Tütün, U; Yay, K, 2011) |
| "Atelectasis also causes post-perfusion lung injury." | 2.78 | Ventilation during cardiopulmonary bypass did not attenuate inflammatory response or affect postoperative outcomes. ( Durukan, AB; Gurbuz, HA; Salman, N; Ucar, HI; Unal, EU; Yorgancioglu, CE, 2013) |
| "Group IV mice had the least acute lung injury, with no detectable interleukin-6 response." | 2.70 | Improved resuscitation minimizes respiratory dysfunction and blunts interleukin-6 and nuclear factor-kappa B activation after traumatic hemorrhage. ( Claridge, JA; Schulman, AM; Young, JS, 2002) |
| "Radiation-induced lung injury (RILI) is a consequence of therapeutic thoracic irradiation (TR) for many cancers, and there are no FDA-approved curative strategies." | 1.91 | Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury. ( Allegood, JC; Camus, SV; Cowart, LA; Freeberg, MAT; Jackson, PD; Liu, J; Pierre-Louis Odoom, J; Sanchez Rosado, RM; Silvey, S; Sime, PJ; Szomju, BB; Thatcher, TH; Toft, R; Weiss, E, 2023) |
| "Acute lung injury often results in significant morbidity and mortality, and current therapeutic modalities have proven to be ineffective." | 1.43 | Nanoparticle facilitated inhalational delivery of erythropoietin receptor cDNA protects against hyperoxic lung injury. ( Gyawali, D; Hsia, CCW; Menon, JU; Moe, OW; Nguyen, KT; Punnakitikashem, P; Ravikumar, P; Takahashi, M; Togao, O; Ye, J; Zhang, J, 2016) |
| "To discuss the risk factors of acute respiratory distress syndrome (ARDS) in patients with sepsis in emergency department." | 1.42 | [Analysis of the risk factors of acute respiratory distress syndrome of Berlin new definition in patients with sepsis in emergency department]. ( Liu, Z; Qiao, L, 2015) |
| "Different animal models of experimental lung injury have been used to investigate mechanisms of lung injury." | 1.42 | Time- and dose-dependent severity of lung injury in a rat model of sepsis. ( Azamfirei, L; Cioc, AD; Copotoiu, SM; Cotoi, OS; Fodor, P; Fodor, RŞ; Georgescu, AM; Grigorescu, BL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 10 (55.56) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Pierre-Louis Odoom, J | 1 |
| Freeberg, MAT | 1 |
| Camus, SV | 1 |
| Toft, R | 1 |
| Szomju, BB | 1 |
| Sanchez Rosado, RM | 1 |
| Jackson, PD | 1 |
| Allegood, JC | 1 |
| Silvey, S | 1 |
| Liu, J | 1 |
| Cowart, LA | 1 |
| Weiss, E | 1 |
| Thatcher, TH | 1 |
| Sime, PJ | 1 |
| Pourfathi, M | 2 |
| Xin, Y | 1 |
| Rosalino, M | 1 |
| Cereda, M | 1 |
| Kadlecek, S | 2 |
| Duncan, I | 1 |
| Profka, H | 2 |
| Hamedani, H | 2 |
| Siddiqui, S | 2 |
| Ruppert, K | 1 |
| Chatterjee, S | 1 |
| Rizi, RR | 1 |
| Kleinveld, DJB | 1 |
| Botros, L | 1 |
| Maas, MAW | 1 |
| Kers, J | 1 |
| Aman, J | 1 |
| Hollmann, MW | 1 |
| Juffermans, NP | 1 |
| Bongard, RD | 1 |
| Yan, K | 1 |
| Hoffmann, RG | 1 |
| Audi, SH | 1 |
| Zhang, X | 1 |
| Lindemer, BJ | 1 |
| Townsley, MI | 1 |
| Merker, MP | 1 |
| Durukan, AB | 1 |
| Gurbuz, HA | 1 |
| Salman, N | 1 |
| Unal, EU | 1 |
| Ucar, HI | 1 |
| Yorgancioglu, CE | 1 |
| Thind, K | 1 |
| Jensen, MD | 1 |
| Hegarty, E | 1 |
| Chen, AP | 1 |
| Lim, H | 1 |
| Martinez-Santiesteban, F | 1 |
| Van Dyk, J | 1 |
| Wong, E | 1 |
| Scholl, TJ | 1 |
| Santyr, GE | 1 |
| Shaghaghi, H | 1 |
| Deshpande, C | 1 |
| Martinez, D | 1 |
| Ishii, M | 1 |
| Rizi, R | 1 |
| Qiao, L | 1 |
| Liu, Z | 1 |
| Ravikumar, P | 1 |
| Menon, JU | 1 |
| Punnakitikashem, P | 1 |
| Gyawali, D | 1 |
| Togao, O | 1 |
| Takahashi, M | 1 |
| Zhang, J | 1 |
| Ye, J | 1 |
| Moe, OW | 1 |
| Nguyen, KT | 1 |
| Hsia, CCW | 1 |
| Fodor, RŞ | 1 |
| Georgescu, AM | 1 |
| Cioc, AD | 1 |
| Grigorescu, BL | 1 |
| Cotoi, OS | 1 |
| Fodor, P | 1 |
| Copotoiu, SM | 1 |
| Azamfirei, L | 1 |
| Morshed, S | 1 |
| Corrales, LA | 1 |
| Lin, K | 1 |
| Miclau, T | 1 |
| Tütün, U | 1 |
| Parlar, AI | 1 |
| Altinay, L | 1 |
| Topcu, DI | 1 |
| Babaroglu, S | 1 |
| Yay, K | 1 |
| Mungan, U | 1 |
| Cicekcioglu, F | 1 |
| Saydam, GS | 1 |
| Katircioglu, SF | 1 |
| Eisenhut, M | 1 |
| Claridge, JA | 1 |
| Schulman, AM | 1 |
| Young, JS | 1 |
| Kellum, JA | 1 |
| Kramer, DJ | 1 |
| Mankad, S | 1 |
| Bellomo, R | 1 |
| Lee, K | 1 |
| Pinsky, MR | 1 |
| De Backer, D | 1 |
| Creteur, J | 1 |
| Zhang, H | 1 |
| Norrenberg, M | 1 |
| Vincent, JL | 1 |
| Cryer, HG | 1 |
| Mavroudis, C | 1 |
| Yu, J | 1 |
| Roberts, AM | 1 |
| Cué, JI | 1 |
| Richardson, JD | 1 |
| Polk, HC | 1 |
| Harmon, JW | 1 |
| Sampson, JA | 1 |
| Graeber, GM | 1 |
| Phillips, Y | 1 |
| Richmond, D | 1 |
2 trials available for lactic acid and Chronic Lung Injury
| Article | Year |
|---|---|
Ventilation during cardiopulmonary bypass did not attenuate inflammatory response or affect postoperative outcomes.
Topics: Aged; Biomarkers; Cardiopulmonary Bypass; Coronary Artery Bypass; Elective Surgical Procedures; Fema | 2013 |
Improved resuscitation minimizes respiratory dysfunction and blunts interleukin-6 and nuclear factor-kappa B activation after traumatic hemorrhage.
Topics: Airway Resistance; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Cardiopulmonary Resuscitat | 2002 |
16 other studies available for lactic acid and Chronic Lung Injury
| Article | Year |
|---|---|
Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury.
Topics: Biomarkers; Breath Tests; Humans; Idiopathic Pulmonary Fibrosis; Lactic Acid; Lung; Lung Injury; Lun | 2023 |
Pulmonary pyruvate metabolism as an index of inflammation and injury in a rat model of acute respiratory distress syndrome.
Topics: Animals; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Adhesion M | 2020 |
Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model.
Topics: Aniline Compounds; Animals; Blood Transfusion; Disease Models, Animal; Endothelium, Vascular; Lactic | 2021 |
Depleted energy charge and increased pulmonary endothelial permeability induced by mitochondrial complex I inhibition are mitigated by coenzyme Q1 in the isolated perfused rat lung.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Blood-Air Barrier; Capillary Permeability; E | 2013 |
Mapping metabolic changes associated with early Radiation Induced Lung Injury post conformal radiotherapy using hyperpolarized ¹³C-pyruvate Magnetic Resonance Spectroscopic Imaging.
Topics: Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Heart; Lactic Acid; Lung; Lung | 2014 |
Metabolic spectroscopy of inflammation in a bleomycin-induced lung injury model using hyperpolarized 1-(13) C pyruvate.
Topics: Analysis of Variance; Animals; Bleomycin; Carbon Isotopes; Disease Models, Animal; Inflammation; Lac | 2014 |
[Analysis of the risk factors of acute respiratory distress syndrome of Berlin new definition in patients with sepsis in emergency department].
Topics: Berlin; Emergency Service, Hospital; Humans; Incidence; Lactic Acid; Lung Injury; Prognosis; Respira | 2015 |
Nanoparticle facilitated inhalational delivery of erythropoietin receptor cDNA protects against hyperoxic lung injury.
Topics: Administration, Inhalation; Animals; Cell Line; DNA, Complementary; Gene Transfer Techniques; Humans | 2016 |
Time- and dose-dependent severity of lung injury in a rat model of sepsis.
Topics: Alanine Transaminase; Animals; Arteries; Aspartate Aminotransferases; Blood Gas Analysis; Blood Urea | 2015 |
Femoral nailing during serum bicarbonate-defined hypo-perfusion predicts pulmonary organ dysfunction in multi-system trauma patients.
Topics: Adult; Anion Transport Proteins; Antiporters; Cohort Studies; Female; Femoral Fractures; Fracture Fi | 2011 |
Does on-pump normothermic beating-heart valve surgery with low tidal volume ventilation protect the lungs?
Topics: Biomarkers; Cardiac Surgical Procedures; Coronary Artery Bypass, Off-Pump; Female; Health Status Ind | 2011 |
The link between inhibition of nitric oxide metabolite production and reduction of LPS induced lung injury.
Topics: Animals; Humans; Lactic Acid; Lipopolysaccharides; Lung Injury; Mice; Models, Animal; Nitric Oxide; | 2012 |
Release of lactate by the lung in acute lung injury.
Topics: Biological Transport, Active; Case-Control Studies; Critical Illness; Humans; Hypoxia; Lactic Acid; | 1997 |
Lactate production by the lungs in acute lung injury.
Topics: Acute Disease; Animals; Cardiac Output; Female; Humans; Infant, Newborn; Lactic Acid; Lung; Lung Inj | 1997 |
Shock, transfusion, and pneumonectomy. Death is due to right heart failure and increased pulmonary vascular resistance.
Topics: Animals; Blood Pressure; Blood Transfusion; Cardiac Output; Cardiac Output, Low; Heart; Lactates; La | 1990 |
Readily available serum chemical markers fail to aid in diagnosis of blast injury.
Topics: Animals; Blast Injuries; Creatine Kinase; Digestive System; L-Lactate Dehydrogenase; Lactates; Lacti | 1988 |