lactic acid has been researched along with Chronic Kidney Diseases in 19 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, if used in excessive doses for patients with kidney disease, it will be contraindicated with side effects such as lactic acidosis." | 9.22 | Lactic Acidosis Associated with Metformin in Patients with Diabetic Kidney Disease. ( Rahman, F; Tuba, S, 2022) |
| "Lactic acidosis is a disease in which lactic acid accumulates in the blood and causes acidosis in the patient." | 8.31 | Metformin-associated severe lactic acidosis combined with multi-organ insufficiency induced by infection with Aeromonas veronii: A case report. ( Wu, C; Xia, Y; Zhu, X, 2023) |
| "To study the incidence of lactic acidosis due to metformin in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) stage 3-5." | 7.91 | Lactic acidosis due to metformin in type 2 diabetes mellitus and chronic kidney disease stage 3-5: is it significant? ( Guddattu, V; Mareddy, AS; Nagaraju, SP; Prabhu, RA; Rangaswamy, D, 2019) |
| "Gap acidosis except lactic acidosis developed and progressed during the CKD stage G5, while lactic acidosis developed in the CKD stages G1-4." | 7.91 | Gap acidosis except lactic acidosis develops and progresses during chronic kidney disease stage G5. ( Tanemoto, M, 2019) |
| " However, if used in excessive doses for patients with kidney disease, it will be contraindicated with side effects such as lactic acidosis." | 5.22 | Lactic Acidosis Associated with Metformin in Patients with Diabetic Kidney Disease. ( Rahman, F; Tuba, S, 2022) |
| "Lactic acidosis is a disease in which lactic acid accumulates in the blood and causes acidosis in the patient." | 4.31 | Metformin-associated severe lactic acidosis combined with multi-organ insufficiency induced by infection with Aeromonas veronii: A case report. ( Wu, C; Xia, Y; Zhu, X, 2023) |
| "To study the incidence of lactic acidosis due to metformin in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) stage 3-5." | 3.91 | Lactic acidosis due to metformin in type 2 diabetes mellitus and chronic kidney disease stage 3-5: is it significant? ( Guddattu, V; Mareddy, AS; Nagaraju, SP; Prabhu, RA; Rangaswamy, D, 2019) |
| "Gap acidosis except lactic acidosis developed and progressed during the CKD stage G5, while lactic acidosis developed in the CKD stages G1-4." | 3.91 | Gap acidosis except lactic acidosis develops and progresses during chronic kidney disease stage G5. ( Tanemoto, M, 2019) |
| "Metformin therapy is limited in patients with chronic kidney disease (CKD) due to the potential risk of lactic acidosis." | 3.78 | Metformin therapy in patients with chronic kidney disease. ( Day, RO; Duong, JK; Furlong, TJ; Graham, GG; Greenfield, JR; Kirkpatrick, CM; Kumar, SS; Roberts, DM; Williams, KM, 2012) |
| "First, in the dose-finding study, the appropriate daily dosing schedules were 1,500 mg (0." | 1.48 | Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4. ( Belpaire, F; Bennis, Y; De Broe, ME; Hurtel-Lemaire, AS; Kajbaf, F; Lalau, JD, 2018) |
| "Urea was extracted iontophoretically over a 2-h period across the skin of adult volunteers and patients with chronic kidney disease." | 1.34 | Assessment of the "skin reservoir" of urea by confocal Raman microspectroscopy and reverse iontophoresis in vivo. ( Caspers, P; de Sterke, J; Guy, RH; Jadoul, M; Préat, V; Wascotte, V, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 9 (47.37) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, Y | 1 |
| Zheng, WL | 1 |
| Shi, QF | 1 |
| Zhang, BY | 1 |
| Yang, GY | 1 |
| Sumbal, R | 1 |
| Ali Baig, MM | 1 |
| Sumbal, A | 1 |
| Rahman, F | 1 |
| Tuba, S | 1 |
| Xia, Y | 1 |
| Zhu, X | 1 |
| Wu, C | 1 |
| Gosmanova, EO | 1 |
| Shahzad, SR | 1 |
| Sumida, K | 1 |
| Kovesdy, CP | 1 |
| Gosmanov, AR | 1 |
| He, LX | 1 |
| Abdolmaleky, HM | 1 |
| Yin, S | 1 |
| Wang, Y | 1 |
| Zhou, JR | 1 |
| Jia, L | 1 |
| Sheng, X | 1 |
| Zamperetti, A | 1 |
| Xie, Y | 1 |
| Corradi, V | 1 |
| Chandel, S | 1 |
| De Cal, M | 1 |
| Montin, DP | 1 |
| Caprara, C | 1 |
| Ronco, C | 1 |
| Han, C | 1 |
| Jiang, YH | 1 |
| Li, W | 1 |
| Liu, Y | 1 |
| Gewin, LS | 1 |
| Lin, YF | 2 |
| Lee, YH | 1 |
| Hsu, YH | 1 |
| Chen, YJ | 1 |
| Cheng, FY | 1 |
| Chiu, HW | 1 |
| Lalau, JD | 1 |
| Kajbaf, F | 1 |
| Bennis, Y | 1 |
| Hurtel-Lemaire, AS | 1 |
| Belpaire, F | 1 |
| De Broe, ME | 1 |
| Weigand, KM | 1 |
| Schirris, TJJ | 1 |
| Houweling, M | 1 |
| van den Heuvel, JJMW | 1 |
| Koenderink, JB | 1 |
| Dankers, ACA | 1 |
| Russel, FGM | 1 |
| Greupink, R | 1 |
| Prabhu, RA | 1 |
| Mareddy, AS | 1 |
| Nagaraju, SP | 1 |
| Rangaswamy, D | 1 |
| Guddattu, V | 1 |
| Tanemoto, M | 1 |
| Watson, EL | 1 |
| Kosmadakis, GC | 1 |
| Smith, AC | 1 |
| Viana, JL | 1 |
| Brown, JR | 1 |
| Molyneux, K | 1 |
| Pawluczyk, IZ | 1 |
| Mulheran, M | 1 |
| Bishop, NC | 1 |
| Shirreffs, S | 1 |
| Maughan, RJ | 1 |
| Owen, PJ | 1 |
| John, SG | 1 |
| McIntyre, CW | 1 |
| Feehally, J | 1 |
| Bevington, A | 1 |
| Kalantar-Zadeh, K | 1 |
| Uppot, RN | 1 |
| Lewandrowski, KB | 1 |
| Ficek, J | 1 |
| Wyskida, K | 1 |
| Ficek, R | 1 |
| Wajda, J | 1 |
| Klein, D | 1 |
| Witkowicz, J | 1 |
| Rotkegel, S | 1 |
| Spiechowicz-Zatoń, U | 1 |
| Kocemba-Dyczek, J | 1 |
| Ciepał, J | 1 |
| Więcek, A | 1 |
| Olszanecka-Glinianowicz, M | 1 |
| Chudek, J | 1 |
| Duong, JK | 1 |
| Roberts, DM | 1 |
| Furlong, TJ | 1 |
| Kumar, SS | 1 |
| Greenfield, JR | 1 |
| Kirkpatrick, CM | 1 |
| Graham, GG | 1 |
| Williams, KM | 1 |
| Day, RO | 1 |
| Wascotte, V | 1 |
| Caspers, P | 1 |
| de Sterke, J | 1 |
| Jadoul, M | 1 |
| Guy, RH | 1 |
| Préat, V | 1 |
3 reviews available for lactic acid and Chronic Kidney Diseases
| Article | Year |
|---|---|
Predictors of Mortality in Acute Mesenteric Ischemia: A Systematic Review and Meta-Analysis.
Topics: Arrhythmias, Cardiac; Creatinine; Female; Humans; Hypotension; Ischemia; Lactic Acid; Male; Mesenter | 2022 |
Lactic Acidosis Associated with Metformin in Patients with Diabetic Kidney Disease.
Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypoglycemic Agents; La | 2022 |
Sugar or Fat? Renal Tubular Metabolism Reviewed in Health and Disease.
Topics: Acute Kidney Injury; Dietary Sugars; Disease Progression; Fatty Acids; Humans; Kidney Tubules; Kidne | 2021 |
1 trial available for lactic acid and Chronic Kidney Diseases
| Article | Year |
|---|---|
Combined walking exercise and alkali therapy in patients with CKD4-5 regulates intramuscular free amino acid pools and ubiquitin E3 ligase expression.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Bicarbonates; Combined Modality Therapy; Exercise Thera | 2013 |
15 other studies available for lactic acid and Chronic Kidney Diseases
| Article | Year |
|---|---|
Clinical characteristics and prognosis in patients with urosepsis from intensive care unit in Shanghai, China: a retrospective bi-centre study.
Topics: Age Distribution; Aged; China; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; | 2021 |
Metformin-associated severe lactic acidosis combined with multi-organ insufficiency induced by infection with Aeromonas veronii: A case report.
Topics: Acidosis, Lactic; Aeromonas veronii; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic A | 2023 |
Metformin is associated with increase in lactate level in elderly patients with type 2 diabetes and CKD stage 3: A case-control study.
Topics: Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Neph | 2020 |
Dietary Fermented Soy Extract and Oligo-Lactic Acid Alleviate Chronic Kidney Disease in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota.
Topics: Adenine; Animals; Biomarkers; Cecum; Clostridium; Cystatin C; Cytokines; Dietary Supplements; Diseas | 2020 |
Combination of biomarker with clinical risk factors for prediction of severe acute kidney injury in critically ill patients.
Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Biomarkers; Clinical Decision Rules; Cont | 2020 |
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
Topics: Animals; Astragalus propinquus; Butyric Acid; Colon; Cyclosporine; Drugs, Chinese Herbal; Endoplasmi | 2021 |
Resveratrol-loaded nanoparticles conjugated with kidney injury molecule-1 as a drug delivery system for potential use in chronic kidney disease.
Topics: Animals; Antibodies; Autophagy; Cell Line; Cell Survival; Creatinine; Drug Carriers; Drug Liberation | 2017 |
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4.
Topics: Creatinine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glycated Hemoglobin | 2018 |
Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity.
Topics: Adenosine Triphosphate; HEK293 Cells; Hepatocytes; Humans; Lactic Acid; Membrane Transport Proteins; | 2019 |
Lactic acidosis due to metformin in type 2 diabetes mellitus and chronic kidney disease stage 3-5: is it significant?
Topics: Acidosis, Lactic; Creatinine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Moni | 2019 |
Gap acidosis except lactic acidosis develops and progresses during chronic kidney disease stage G5.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Aged; Aged, 80 and over; Biomarkers; Disease Prog | 2019 |
Case records of the Massachusetts General Hospital. Case 23-2013. A 54-year-old woman with abdominal pain, vomiting, and confusion.
Topics: Abdominal Pain; Acidosis, Lactic; Confusion; Diabetes Mellitus, Type 2; Diagnosis, Differential; Fem | 2013 |
Relationship between plasma levels of zonulin, bacterial lipopolysaccharides, D-lactate and markers of inflammation in haemodialysis patients.
Topics: Biomarkers; C-Reactive Protein; Cholera Toxin; Female; Haptoglobins; Humans; Inflammation; Interleuk | 2017 |
Metformin therapy in patients with chronic kidney disease.
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Dose-Response Relationship, Dr | 2012 |
Assessment of the "skin reservoir" of urea by confocal Raman microspectroscopy and reverse iontophoresis in vivo.
Topics: Adult; Humans; Iontophoresis; Lactic Acid; Microscopy, Confocal; Renal Insufficiency, Chronic; Sever | 2007 |