lactic acid has been researched along with Chronic Illness in 127 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the role of chronic cerebral lactic acidosis in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)." | 9.11 | Cerebral lactic acidosis correlates with neurological impairment in MELAS. ( De Vivo, DC; DiMauro, S; Engelstad, K; Hirano, M; Jhung, S; Kaufmann, P; Mao, X; Mitsis, E; Sano, MC; Shanske, S; Shungu, DC, 2004) |
| "The purpose of this study was to investigate the curative effect of bone-like hydroxyapatite/poly amino acid (BHA/PAA) as a carrier for poly(lactic-co-glycolic acid)-coated rifapentine microsphere (RPM) in the treatment of rabbit chronic osteomyelitis induced by Staphylococcus aureus." | 7.81 | Treatment of Staphylococcus aureus-induced chronic osteomyelitis with bone-like hydroxyapatite/poly amino acid loaded with rifapentine microspheres. ( Cao, ZD; Jiang, DM; Li, YJ; Wang, X; Wang, ZL; Wu, J; Yan, L; Yi, YF, 2015) |
| " All cases of lactic acidosis (pH, ≤ 7." | 7.80 | Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy. ( Giampreti, A; Locatelli, CA; Lonati, D; Manzo, L; Papa, P; Petrolini, VM; Protti, A; Rocchi, L; Rognoni, C; Rolandi, L; Valli, A; Vecchio, S, 2014) |
| "The present study assesses whether ranolazine increases left ventricular (LV) function without an increase in myocardial oxygen consumption (MVO2) and thus improves LV mechanical efficiency in dogs with heart failure (HF)." | 7.71 | Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure. ( Blackburn, B; Chandler, MP; Morita, H; Roth, BA; Sabbah, HN; Stanley, WC; Suzuki, G; Wolff, A, 2002) |
| "To evaluate purine degradation in patients with congestive heart failure concentrations of serum hypoxanthine, lactate, and noradrenaline were measured before and after submaximal treadmill exercise in 12 patients with chronic congestive heart failure and nine healthy volunteers." | 7.68 | Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure. ( Hisatome, I; Ishiko, R; Kinugawa, T; Kitamura, H; Kobayashi, M; Kotake, H; Mashiba, H; Miyakoda, H; Saito, M; Sato, R, 1990) |
| "Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients." | 5.35 | Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009) |
| "The prevalence of prostatitis is extremely high, with vast majority belongs to National Institutes of Health Category III: Chronic Prostatitis (CP)/Chronic Pelvic Pain Syndromes (CPPS)." | 5.35 | Frequent ejaculation associated free radical and lactic acid accumulation cause noninfectious inflammation and muscle dysfunction: a potential mechanism for symptoms in Chronic Prostatitis/Chronic Pelvic Pain Syndrome. ( Chen, Q; Peng, H; Tan, Y, 2009) |
| "To evaluate the role of chronic cerebral lactic acidosis in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)." | 5.11 | Cerebral lactic acidosis correlates with neurological impairment in MELAS. ( De Vivo, DC; DiMauro, S; Engelstad, K; Hirano, M; Jhung, S; Kaufmann, P; Mao, X; Mitsis, E; Sano, MC; Shanske, S; Shungu, DC, 2004) |
| "The FDA approved 'label' for metformin lists hepatic insufficiency as a risk for lactic acidosis." | 3.96 | The safety and pharmacokinetics of metformin in patients with chronic liver disease. ( Braithwaite, HE; Carland, JE; Cheng, TS; Danta, M; Day, RO; Graham, GG; Greenfield, JR; Kumar, SS; Liu, Z; Smith, FC; Stocker, SL; Williams, KM, 2020) |
| "The purpose of this study was to investigate the curative effect of bone-like hydroxyapatite/poly amino acid (BHA/PAA) as a carrier for poly(lactic-co-glycolic acid)-coated rifapentine microsphere (RPM) in the treatment of rabbit chronic osteomyelitis induced by Staphylococcus aureus." | 3.81 | Treatment of Staphylococcus aureus-induced chronic osteomyelitis with bone-like hydroxyapatite/poly amino acid loaded with rifapentine microspheres. ( Cao, ZD; Jiang, DM; Li, YJ; Wang, X; Wang, ZL; Wu, J; Yan, L; Yi, YF, 2015) |
| " All cases of lactic acidosis (pH, ≤ 7." | 3.80 | Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy. ( Giampreti, A; Locatelli, CA; Lonati, D; Manzo, L; Papa, P; Petrolini, VM; Protti, A; Rocchi, L; Rognoni, C; Rolandi, L; Valli, A; Vecchio, S, 2014) |
| "Increased brain lactate, and not glutamine, is a primary player in the pathogenesis of brain edema in CLD." | 3.80 | Increased brain lactate is central to the development of brain edema in rats with chronic liver disease. ( Bosoi, CR; Huynh, J; Marin, H; Parent-Robitaille, C; Rose, CF; Tremblay, M; Zwingmann, C, 2014) |
| "The purpose of this study is to explore depression metabolic markers in rat hippocampus and to investigate the anti-depressant effect of genipin and its mechanisms using nuclear magnetic resonance (NMR) metabonomics." | 3.80 | [1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. ( Gao, S; Peng, GJ; Qin, XM; Shi, BY; Tian, JS, 2014) |
| "This study investigated the effects of high-intensity training, with or without induced metabolic alkalosis, on lactate transporter (MCT1 and MCT4) and sodium bicarbonate cotransporter (NBC) content in rat skeletal muscles." | 3.74 | Effects of high-intensity training on MCT1, MCT4, and NBC expressions in rat skeletal muscles: influence of chronic metabolic alkalosis. ( Bishop, D; Mercier, J; Moore-Morris, T; Thomas, C, 2007) |
| "The present study assesses whether ranolazine increases left ventricular (LV) function without an increase in myocardial oxygen consumption (MVO2) and thus improves LV mechanical efficiency in dogs with heart failure (HF)." | 3.71 | Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure. ( Blackburn, B; Chandler, MP; Morita, H; Roth, BA; Sabbah, HN; Stanley, WC; Suzuki, G; Wolff, A, 2002) |
| "In 516 patient-years of observation, two patients experienced severe fulminant lactic acidosis (lactate > 5 mmol/l) and hepatic steatosis attributable to nucleoside analogue reverse transcriptase inhibitors (NRTI)." | 3.71 | Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. ( James, IR; John, M; Mallal, SA; McKinnon, EJ; Moore, CB; Nolan, D; Upton, RP, 2001) |
| "To evaluate purine degradation in patients with congestive heart failure concentrations of serum hypoxanthine, lactate, and noradrenaline were measured before and after submaximal treadmill exercise in 12 patients with chronic congestive heart failure and nine healthy volunteers." | 3.68 | Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure. ( Hisatome, I; Ishiko, R; Kinugawa, T; Kitamura, H; Kobayashi, M; Kotake, H; Mashiba, H; Miyakoda, H; Saito, M; Sato, R, 1990) |
| "In 10 patients with treated chronic periodontitis, we randomly selected the 1st molars in the mandible with buccal degree II furcation involvement for either polylactic-citric-acid-ester (PLA) or glycolide-lactic-copolymer (PGL) GTR membrane therapy." | 2.70 | PMN responses following use of 2 biodegradable GTR membranes. ( Buchmann, R; Hasilik, A; Heinecke, A; Lange, DE, 2001) |
| "Treatment with clonidine markedly suppressed norepinephrine levels during exercise (matched peak exercise workload: control, 2137 +/- 187 versus clonidine, 1430 +/- 161 pg/mL), increased leg blood flow (control, 1." | 2.68 | Effect of sympathoinhibition on exercise performance in patients with heart failure. ( Chomsky, DB; Lang, CC; Rayos, GH; Wilson, JR; Wood, AJ, 1997) |
| "The study cohort comprised 90 pediatric septic shock patients admitted from February 2012 to May 2015." | 1.62 | Association between the lactate/albumin ratio and mortality in pediatric septic shock patients with underlying chronic disease: retrospective pilot study. ( Choi, SJ; Ha, EJ; Jhang, WK; Park, SJ, 2021) |
| "According to the new definition of septic shock, vasopressor therapy and hyperlactatemia are essential for diagnosis." | 1.51 | Risk factors for mortality in patients with low lactate level and septic shock. ( Choi, JY; Jeong, SJ; Jeong, WY; Jung, IY; Kim, EJ; Kim, JM; Kim, MH; Kim, YC; Ku, NS; Oh, DH; Song, JE; Song, YG, 2019) |
| "Treatment and management of chronic wounds is a large burden on the health sector and causes substantial suffering for the patients." | 1.43 | A pilot study investigating lactic acid bacterial symbionts from the honeybee in inhibiting human chronic wound pathogens. ( Butler, É; Lindholm, C; Nilson, B; Oien, RF; Olofsson, TC; Vásquez, A, 2016) |
| "Secondary hyperparathyroidism is not involved in postoperative bone loss." | 1.39 | Roux-en-Y gastric bypass surgery reduces bone mineral density and induces metabolic acidosis in rats. ( Abegg, K; Bueter, M; Gehring, N; Liesegang, A; Lutz, TA; Schiesser, M; Wagner, CA, 2013) |
| "Alcohol ketoacidosis is a frequently missed diagnosis, but is well described in the literature." | 1.39 | Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient. ( Dwyer, JB; Tamama, K, 2013) |
| "Hypoglycemia is common during development and is associated with the risk of neurodevelopmental deficits in human infants." | 1.36 | Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia. ( Ennis, K; Gruetter, R; Long, JD; Rao, R; Tkac, I; Ugurbil, K, 2010) |
| "The prevalence of prostatitis is extremely high, with vast majority belongs to National Institutes of Health Category III: Chronic Prostatitis (CP)/Chronic Pelvic Pain Syndromes (CPPS)." | 1.35 | Frequent ejaculation associated free radical and lactic acid accumulation cause noninfectious inflammation and muscle dysfunction: a potential mechanism for symptoms in Chronic Prostatitis/Chronic Pelvic Pain Syndrome. ( Chen, Q; Peng, H; Tan, Y, 2009) |
| "Mitochondrial disorders were detected by analysis of serum lactate and thymidine phosphorylase activities, brain magnetic resonance images, and muscle biopsies." | 1.35 | Frequency of mitochondrial defects in patients with chronic intestinal pseudo-obstruction. ( Amiot, A; Hatem, DC; Jardel, C; Joly, F; Lombès, A; Messing, B; Slama, A; Tchikviladzé, M, 2009) |
| "Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients." | 1.35 | Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009) |
| "Additionally, the lipid content in pancreatic cancer was higher than that in chronic pancreatitis." | 1.34 | Discrimination of metabolic profiles of pancreatic cancer from chronic pancreatitis by high-resolution magic angle spinning 1H nuclear magnetic resonance and principal components analysis. ( Chen, Q; Deng, H; Fang, F; He, X; Lu, J; Spraul, M; Yu, Y, 2007) |
| "Our data also suggest that chronic hypoxemia depresses mechanosensitive muscle afferents." | 1.32 | Comparison between the effects of chronic and acute hypoxemia on muscle afferent activities from the tibialis anterior muscle. ( Decherchi, P; Dousset, E; Grelot, L; Jammes, Y, 2003) |
| "Compared with a control group, COPD patients had lower MVCs, an attenuated decrease in MF during exercise, lower resting level of GSH, no posthandgrip TBARS increase and no GSH consumption." | 1.32 | Influence of chronic hypoxemia on peripheral muscle function and oxidative stress in humans. ( Barbier, D; Faucher, M; Hug, F; Jammes, Y; Steinberg, JG, 2004) |
| "Lactic acidosis has been implicated; however, increases in the excitotoxic amino acid glutamate, which correlate with increased neuronal damage, may be the cause for the increased damage seen in hyperglycemic stroke." | 1.31 | The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex. ( Diaz, FG; Guyot, LL; O'Regan, MH; Phillis, JW; Song, D, 2001) |
| "In case of fatal hydrocephalus, high lactate levels were observed throughout the whole brain." | 1.30 | In vivo 1H MR spectroscopic imaging and diffusion weighted MRI in experimental hydrocephalus. ( Braun, KP; de Graaf, RA; Gooskens, RH; Nicolay, K; Tulleken, KA; Vandertop, WP, 1998) |
| "Chronic alkalosis was induced by chloride restriction and the administration of sodium bicarbonate and furosemide." | 1.27 | Renal tubular biochemistry during acute and chronic metabolic alkalosis in the dog. ( Aranda, MR; Ibanez, RJ; Kiss, AL; Lemieux, C; Lemieux, G, 1985) |
| "In inactive liver cirrhosis of alcoholic etiology, the concentrations of lactic and uric acids tended toward reduction, however, they were significantly higher than in the group of patients with virus liver lesions." | 1.27 | [Diagnostic significance of determining the blood content of lactic and uric acids in chronic liver lesions of alcoholic and viral etiologies]. ( Blok, IuE; Dzhalalov, KD; Loginov, AS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (13.39) | 18.7374 |
| 1990's | 26 (20.47) | 18.2507 |
| 2000's | 42 (33.07) | 29.6817 |
| 2010's | 35 (27.56) | 24.3611 |
| 2020's | 7 (5.51) | 2.80 |
| Authors | Studies |
|---|---|
| de Boer, E | 1 |
| Petrache, I | 1 |
| Goldstein, NM | 1 |
| Olin, JT | 1 |
| Keith, RC | 1 |
| Modena, B | 1 |
| Mohning, MP | 1 |
| Yunt, ZX | 1 |
| San-Millán, I | 1 |
| Swigris, JJ | 1 |
| Ilginel, MT | 1 |
| Yesilyurt, AO | 1 |
| Ozyilmaz, E | 1 |
| Ilginel, OO | 1 |
| Sener, M | 1 |
| Tunay, DL | 1 |
| Karacaer, F | 1 |
| Biricik, E | 1 |
| Ucar, MA | 1 |
| Abdul Rahim, R | 1 |
| Jayusman, PA | 1 |
| Muhammad, N | 1 |
| Ahmad, F | 1 |
| Mokhtar, N | 1 |
| Naina Mohamed, I | 1 |
| Mohamed, N | 1 |
| Shuid, AN | 1 |
| Smith, FC | 1 |
| Stocker, SL | 1 |
| Danta, M | 1 |
| Carland, JE | 1 |
| Kumar, SS | 1 |
| Liu, Z | 1 |
| Greenfield, JR | 1 |
| Braithwaite, HE | 1 |
| Cheng, TS | 1 |
| Graham, GG | 1 |
| Williams, KM | 1 |
| Day, RO | 1 |
| Markowiak-Kopeć, P | 1 |
| Śliżewska, K | 1 |
| Nuzzo, A | 1 |
| Joly, F | 2 |
| Ronot, M | 1 |
| Castier, Y | 1 |
| Huguet, A | 1 |
| Paugam-Burtz, C | 1 |
| Cazals-Hatem, D | 1 |
| Tran-Dinh, A | 1 |
| Becq, A | 1 |
| Panis, Y | 1 |
| Bouhnik, Y | 1 |
| Maggiori, L | 1 |
| Corcos, O | 1 |
| Rha, MS | 1 |
| Han, JW | 1 |
| Koh, JY | 1 |
| Lee, HS | 1 |
| Kim, JH | 1 |
| Cho, K | 1 |
| Kim, SI | 1 |
| Kim, MS | 1 |
| Lee, JG | 1 |
| Park, SH | 2 |
| Joo, DJ | 1 |
| Park, JY | 1 |
| Shin, EC | 1 |
| Lundgaard, E | 1 |
| Wouda, MF | 1 |
| Strøm, V | 1 |
| Oh, DH | 1 |
| Kim, MH | 1 |
| Jeong, WY | 1 |
| Kim, YC | 1 |
| Kim, EJ | 1 |
| Song, JE | 1 |
| Jung, IY | 1 |
| Jeong, SJ | 1 |
| Ku, NS | 1 |
| Choi, JY | 1 |
| Song, YG | 1 |
| Kim, JM | 1 |
| Tulbah, AS | 1 |
| Pisano, E | 1 |
| Scalia, S | 1 |
| Young, PM | 1 |
| Traini, D | 1 |
| Ong, HX | 1 |
| Xia, N | 1 |
| Zhou, T | 1 |
| Liang, X | 1 |
| Ye, S | 1 |
| Zhao, P | 1 |
| Yang, J | 1 |
| Zhou, Y | 1 |
| Zhao, J | 1 |
| Shen, B | 1 |
| van der Heijden, DJ | 1 |
| van Leeuwen, MAH | 1 |
| Ritt, MJPF | 1 |
| van de Ven, PM | 1 |
| van Royen, N | 1 |
| Mujeeb-U-Rahman, M | 1 |
| Honarvar Nazari, M | 1 |
| Sencan, M | 1 |
| Jeppesen, JB | 1 |
| Mortensen, C | 1 |
| Bendtsen, F | 1 |
| Møller, S | 1 |
| Szabó, T | 1 |
| Postrach, E | 1 |
| Mähler, A | 1 |
| Kung, T | 1 |
| Turhan, G | 1 |
| von Haehling, S | 1 |
| Anker, SD | 2 |
| Boschmann, M | 1 |
| Doehner, W | 1 |
| Abegg, K | 1 |
| Gehring, N | 1 |
| Wagner, CA | 1 |
| Liesegang, A | 1 |
| Schiesser, M | 1 |
| Bueter, M | 1 |
| Lutz, TA | 1 |
| Dasararaju, R | 1 |
| Many, WJ | 1 |
| Samant, JS | 1 |
| Vecchio, S | 1 |
| Giampreti, A | 1 |
| Petrolini, VM | 1 |
| Lonati, D | 1 |
| Protti, A | 1 |
| Papa, P | 1 |
| Rognoni, C | 1 |
| Valli, A | 1 |
| Rocchi, L | 1 |
| Rolandi, L | 1 |
| Manzo, L | 1 |
| Locatelli, CA | 1 |
| Bosoi, CR | 1 |
| Zwingmann, C | 1 |
| Marin, H | 1 |
| Parent-Robitaille, C | 1 |
| Huynh, J | 1 |
| Tremblay, M | 1 |
| Rose, CF | 1 |
| Peng, GJ | 1 |
| Shi, BY | 1 |
| Tian, JS | 1 |
| Gao, S | 1 |
| Qin, XM | 1 |
| Aquilani, R | 2 |
| D'Antona, G | 1 |
| Baiardi, P | 1 |
| Gambino, A | 1 |
| Iadarola, P | 1 |
| Viglio, S | 1 |
| Pasini, E | 2 |
| Verri, M | 1 |
| Barbieri, A | 1 |
| Boschi, F | 1 |
| Butler, É | 1 |
| Oien, RF | 1 |
| Lindholm, C | 1 |
| Olofsson, TC | 1 |
| Nilson, B | 1 |
| Vásquez, A | 1 |
| Karlsson, L | 1 |
| Gerdle, B | 2 |
| Ghafouri, B | 1 |
| Bäckryd, E | 1 |
| Olausson, P | 1 |
| Ghafouri, N | 1 |
| Larsson, B | 2 |
| Kilpinen, S | 1 |
| Rantala, M | 1 |
| Spillmann, T | 1 |
| Björkroth, J | 1 |
| Westermarck, E | 1 |
| Yan, L | 1 |
| Jiang, DM | 1 |
| Cao, ZD | 1 |
| Wu, J | 1 |
| Wang, X | 2 |
| Wang, ZL | 1 |
| Li, YJ | 1 |
| Yi, YF | 1 |
| Francica, JV | 1 |
| Bigongiari, A | 1 |
| Mochizuki, L | 1 |
| Scapini, KB | 1 |
| Moraes, OA | 1 |
| Mostarda, C | 1 |
| Caperuto, EC | 1 |
| Irigoyen, MC | 1 |
| De Angelis, K | 1 |
| Rodrigues, B | 1 |
| Henning, DJ | 1 |
| Oedorf, K | 1 |
| Day, DE | 1 |
| Redfield, CS | 1 |
| Huguenel, CJ | 1 |
| Roberts, JC | 1 |
| Sanchez, LD | 1 |
| Wolfe, RE | 1 |
| Shapiro, NI | 1 |
| Uemura, T | 1 |
| Yamamuro, M | 1 |
| Kaikita, K | 1 |
| Takashio, S | 1 |
| Utsunomiya, D | 1 |
| Hirakawa, K | 1 |
| Nakayama, M | 1 |
| Sakamoto, K | 1 |
| Yamamoto, E | 1 |
| Tsujita, K | 1 |
| Kojima, S | 1 |
| Hokimoto, S | 1 |
| Yamashita, Y | 1 |
| Ogawa, H | 1 |
| d'Angelo, I | 1 |
| Perfetto, B | 1 |
| Costabile, G | 1 |
| Ambrosini, V | 1 |
| Caputo, P | 1 |
| Miro, A | 1 |
| d'Emmanuele di Villa Bianca, R | 1 |
| Sorrentino, R | 1 |
| Donnarumma, G | 1 |
| Quaglia, F | 2 |
| Ungaro, F | 2 |
| Choi, SJ | 1 |
| Ha, EJ | 1 |
| Jhang, WK | 1 |
| Park, SJ | 1 |
| Ferrando-Vivas, P | 1 |
| Jones, A | 1 |
| Rowan, KM | 1 |
| Harrison, DA | 1 |
| Cooper, CB | 1 |
| Dolezal, BA | 1 |
| Neufeld, EV | 1 |
| Shieh, P | 1 |
| Jenner, JR | 1 |
| Riley, M | 1 |
| Li, Y | 1 |
| Mei, L | 1 |
| Qiang, J | 1 |
| Ju, S | 1 |
| Zhao, S | 1 |
| Atchley, DS | 1 |
| Foster, JA | 1 |
| Bavis, RW | 1 |
| Marcoux, J | 1 |
| McArthur, DA | 1 |
| Miller, C | 1 |
| Glenn, TC | 1 |
| Villablanca, P | 1 |
| Martin, NA | 1 |
| Hovda, DA | 1 |
| Alger, JR | 1 |
| Vespa, PM | 1 |
| Sadove, R | 1 |
| Pai, S | 1 |
| Smit, A | 1 |
| Birch, A | 1 |
| Hayton, M | 1 |
| Mensink, PB | 1 |
| Hol, L | 1 |
| Borghuis-Koertshuis, N | 1 |
| Geelkerken, RH | 1 |
| Huisman, AB | 1 |
| Doelman, CJ | 1 |
| van Vuuren, AJ | 1 |
| Kuipers, EJ | 1 |
| Kolkman, JJ | 1 |
| Amiot, A | 1 |
| Tchikviladzé, M | 1 |
| Slama, A | 1 |
| Hatem, DC | 1 |
| Jardel, C | 1 |
| Messing, B | 1 |
| Lombès, A | 1 |
| Suzuki, Y | 1 |
| Oyane, A | 1 |
| Ikeno, F | 1 |
| Lyons, JK | 1 |
| Yeung, AC | 1 |
| Hu, Q | 1 |
| Suzuki, G | 2 |
| Young, RF | 1 |
| Page, BJ | 1 |
| Fallavollita, JA | 1 |
| Canty, JM | 1 |
| De Stefano, D | 1 |
| De Rosa, G | 1 |
| Maiuri, MC | 1 |
| Iuvone, T | 1 |
| Cinelli, MP | 1 |
| La Rotonda, MI | 1 |
| Carnuccio, R | 1 |
| Peng, H | 1 |
| Chen, Q | 2 |
| Tan, Y | 1 |
| Rao, R | 1 |
| Ennis, K | 1 |
| Long, JD | 1 |
| Ugurbil, K | 1 |
| Gruetter, R | 1 |
| Tkac, I | 1 |
| Gelain, F | 1 |
| Panseri, S | 1 |
| Antonini, S | 1 |
| Cunha, C | 1 |
| Donega, M | 1 |
| Lowery, J | 1 |
| Taraballi, F | 1 |
| Cerri, G | 1 |
| Montagna, M | 1 |
| Baldissera, F | 1 |
| Vescovi, A | 1 |
| de Almeida, SM | 1 |
| Boritza, K | 1 |
| Cogo, LL | 1 |
| Pessa, L | 1 |
| França, J | 1 |
| Rota, I | 1 |
| Muro, M | 1 |
| Ribeiro, C | 1 |
| Raboni, SM | 1 |
| Vidal, LR | 1 |
| Nogueira, MB | 1 |
| Ellis, R | 1 |
| Rama Rao, KV | 1 |
| Norenberg, MD | 1 |
| Nirupama, R | 1 |
| Devaki, M | 1 |
| Yajurvedi, HN | 1 |
| Na, MH | 1 |
| Yao, CZ | 1 |
| Yu, XT | 1 |
| Jiang, MX | 1 |
| Sim, DS | 1 |
| Jeong, MH | 1 |
| Cha, KR | 1 |
| Park, JO | 1 |
| Shin, YM | 1 |
| Shin, H | 1 |
| Hong, YJ | 1 |
| Ahn, Y | 1 |
| Schwartz, RS | 1 |
| Kang, JC | 1 |
| Dwyer, JB | 1 |
| Tamama, K | 1 |
| Lee, SJ | 1 |
| Kirigiti, M | 1 |
| Lindsley, SR | 1 |
| Loche, A | 1 |
| Madden, CJ | 1 |
| Morrison, SF | 1 |
| Smith, MS | 1 |
| Grove, KL | 1 |
| Chandler, MP | 1 |
| Stanley, WC | 1 |
| Morita, H | 1 |
| Roth, BA | 1 |
| Blackburn, B | 1 |
| Wolff, A | 1 |
| Sabbah, HN | 1 |
| Alfredson, H | 1 |
| Bjur, D | 1 |
| Thorsen, K | 1 |
| Lorentzon, R | 1 |
| Sandström, P | 1 |
| Jacob, RJ | 1 |
| Fan, X | 1 |
| Evans, ML | 1 |
| Dziura, J | 1 |
| Sherwin, RS | 1 |
| Dousset, E | 1 |
| Decherchi, P | 1 |
| Grelot, L | 1 |
| Jammes, Y | 2 |
| Ehmke, B | 1 |
| Rüdiger, SG | 1 |
| Hommens, A | 1 |
| Karch, H | 1 |
| Flemmig, TF | 1 |
| Paquette, DW | 1 |
| Nikolaidis, LA | 1 |
| Sturzu, A | 1 |
| Stolarski, C | 1 |
| Elahi, D | 1 |
| Shen, YT | 1 |
| Shannon, RP | 1 |
| Faucher, M | 1 |
| Steinberg, JG | 1 |
| Barbier, D | 1 |
| Hug, F | 1 |
| Kaufmann, P | 1 |
| Shungu, DC | 1 |
| Sano, MC | 1 |
| Jhung, S | 1 |
| Engelstad, K | 1 |
| Mitsis, E | 1 |
| Mao, X | 1 |
| Shanske, S | 1 |
| Hirano, M | 1 |
| DiMauro, S | 1 |
| De Vivo, DC | 1 |
| Brownell, AL | 1 |
| Chen, YI | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of the Administration of Melatonin and Metformin on Glycemic Control, Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes: Pilot Study[NCT03848533] | Phase 2 | 42 participants (Anticipated) | Interventional | 2019-08-22 | Recruiting | ||
| Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy[NCT04222101] | 9 participants (Actual) | Interventional | 2019-10-07 | Terminated (stopped due to COVID-19 pandemic) | |||
| Impaired Tissue Oxygen Delivery in Patients With Coexistent COPD-heart Failure: What Consequences on Neuromuscular Fatigue During Exercise?[NCT05235685] | 40 participants (Anticipated) | Interventional | 2023-02-21 | Recruiting | |||
| Is Non-invasive Ventilation Effective in Improving the Exercise Capacity in Patients With Cardiac Heart Failure?: A Randomized Controlled Trial[NCT05433610] | 12 participants (Actual) | Interventional | 2022-06-28 | Completed | |||
| Brain During Effort : Effects of Hypoxia With Respiratory Patients[NCT02854280] | 33 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| Assessing the Relationship Between Fatigue and Mitochondrial Toxicity in Patients With HIV/AIDS[NCT00106795] | 82 participants (Actual) | Observational | 2005-03-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for lactic acid and Chronic Illness
| Article | Year |
|---|---|
Recent Advances in Nanoencapsulation Systems Using PLGA of Bioactive Phenolics for Protection against Chronic Diseases.
Topics: Chronic Disease; Drug Delivery Systems; Humans; Lactic Acid; Nanoparticles; Phenols; Polyglycolic Ac | 2019 |
The Effect of Probiotics on the Production of Short-Chain Fatty Acids by Human Intestinal Microbiome.
Topics: Bifidobacterium; Carbon; Chronic Disease; Diet; Fatty Acids, Volatile; Gastrointestinal Microbiome; | 2020 |
Essential amino acids and exercise tolerance in elderly muscle-depleted subjects with chronic diseases: a rehabilitation without rehabilitation?
Topics: Aged; Aged, 80 and over; Chronic Disease; Exercise Therapy; Exercise Tolerance; Female; Heart Failur | 2014 |
Brain energy metabolism and mitochondrial dysfunction in acute and chronic hepatic encephalopathy.
Topics: Acute Disease; Ammonia; Brain; Chronic Disease; Citric Acid Cycle; Energy Metabolism; Glycolysis; He | 2012 |
The neurology of hypertension, a neurologist view.
Topics: Adult; Blood-Brain Barrier; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; | 1982 |
Pathophysiology of hibernation, stunning, and ischemic preconditioning.
Topics: Animals; Chronic Disease; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Stun | 1998 |
11 trials available for lactic acid and Chronic Illness
| Article | Year |
|---|---|
Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Chronic Disease; Diarrhea; Dogs; Double-Blind | 2015 |
[Effects of added therapy with Chinese herbal medicine Kanli Granule on skeletal muscle dysfunction in patients with chronic heart failure].
Topics: Aged; Chronic Disease; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Lactic Acid; Male; Midd | 2012 |
Minocycline microspheres: a complementary medical-mechanical model for the treatment of chronic periodontitis.
Topics: Analysis of Variance; Anti-Bacterial Agents; Chronic Disease; Delayed-Action Preparations; Dental Sc | 2002 |
Cerebral lactic acidosis correlates with neurological impairment in MELAS.
Topics: Acidosis, Lactic; Adult; Blood Glucose; Cerebral Ventricles; Chronic Disease; DNA Mutational Analysi | 2004 |
Influence of insulin and free fatty acids on contractile function in patients with chronically stunned and hibernating myocardium.
Topics: Aged; Blood Glucose; Chronic Disease; Cicatrix; Cross-Over Studies; Diastole; Drug Combinations; Ech | 2005 |
The influence of acute and 23 days of intermittent hypoxic exposures on the exercise-induced forehead sweating response.
Topics: Acclimatization; Acute Disease; Adult; Altitude; Blood Pressure; Body Temperature Regulation; Chroni | 2007 |
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To | 2008 |
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To | 2008 |
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To | 2008 |
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To | 2008 |
Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure.
Topics: Chronic Disease; Dyspnea; Exercise; Fatigue; Female; Heart Failure; Heart Rate; Hemodynamics; Humans | 1996 |
Effect of sympathoinhibition on exercise performance in patients with heart failure.
Topics: Cardiomyopathy, Dilated; Chronic Disease; Clonidine; Coronary Disease; Exercise; Exercise Test; Hemo | 1997 |
PMN responses following use of 2 biodegradable GTR membranes.
Topics: Absorbable Implants; beta-N-Acetylhexosaminidases; Chronic Disease; Dental Plaque Index; Female; Fol | 2001 |
[Physical training as interval or continuous training in chronic heart failure for improving functional capacity, hemodynamics and quality of life--a controlled study].
Topics: Activities of Daily Living; Cardiac Output; Chronic Disease; Exercise Test; Female; Follow-Up Studie | 2002 |
110 other studies available for lactic acid and Chronic Illness
| Article | Year |
|---|---|
Decreased Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome.
Topics: Adult; Chronic Disease; COVID-19; Exercise; Fatty Acids; Female; Humans; Lactic Acid; Lipid Metaboli | 2022 |
Evaluation of factors affecting treatment and mortality in patients over 65 years of age and without chronic disease, followed in the Intensive Care Unit due to COVID-19.
Topics: Aged; Aged, 80 and over; Chronic Disease; COVID-19; Cross-Sectional Studies; Female; Humans; Intensi | 2023 |
The safety and pharmacokinetics of metformin in patients with chronic liver disease.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Chronic Disease; Comorbidity; Cross-Sectional Stud | 2020 |
Normal Lactate and Unenhanced CT-Scan Result in Delayed Diagnosis of Acute Mesenteric Ischemia.
Topics: Abdominal Pain; Acute Disease; Adult; Anastomosis, Surgical; Chronic Disease; Cohort Studies; Colon; | 2020 |
Impaired antibacterial response of liver sinusoidal Vγ9
Topics: Case-Control Studies; Chronic Disease; Endotoxins; Escherichia coli; Female; Humans; Lactic Acid; Li | 2022 |
A comparative study of two protocols for treadmill walking exercise testing in ambulating subjects with incomplete spinal cord injury.
Topics: Adolescent; Adult; Aged; Blood Pressure; Chronic Disease; Exercise Test; Female; Heart Rate; Humans; | 2017 |
Risk factors for mortality in patients with low lactate level and septic shock.
Topics: Aged; APACHE; C-Reactive Protein; Chronic Disease; Cohort Studies; Female; Heart Failure; Humans; Hy | 2019 |
Inhaled simvastatin nanoparticles for inflammatory lung disease.
Topics: Administration, Inhalation; Anti-Inflammatory Agents; Biological Transport; Chemistry, Pharmaceutica | 2017 |
A Lactate Fermentation Mutant of
Topics: Acute Disease; Animals; Antibodies, Protozoan; Cattle; Cells, Cultured; Chronic Disease; Fermentatio | 2018 |
Chronic radial artery occlusion does not cause exercise induced hand ischemia.
Topics: Aged; Arterial Occlusive Diseases; Blood Gas Monitoring, Transcutaneous; Cardiac Catheterization; Ch | 2018 |
A novel semiconductor based wireless electrochemical sensing platform for chronic disease management.
Topics: Biosensing Techniques; Chronic Disease; Equipment Design; Glucose; Humans; Lactic Acid; Oxygen; Semi | 2019 |
Lactate metabolism in chronic liver disease.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Chronic Disease; Fasting; Female; Femoral Artery; Gal | 2013 |
Increased catabolic activity in adipose tissue of patients with chronic heart failure.
Topics: Adipose Tissue; Adult; Aged; Atrial Natriuretic Factor; Blood Glucose; Cachexia; Case-Control Studie | 2013 |
Roux-en-Y gastric bypass surgery reduces bone mineral density and induces metabolic acidosis in rats.
Topics: Acidosis; Animals; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Calcium; Chronic Disea | 2013 |
Perplexity of a fungus in the sinus.
Topics: Adolescent; Amphotericin B; Antifungal Agents; Ascomycota; Benzenesulfonates; Brain Abscess; Central | 2014 |
Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Chronic Disease; Creatinine; | 2014 |
Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.
Topics: Ammonia; Animals; Brain; Brain Edema; Chronic Disease; Glutamine; Hepatic Encephalopathy; Lactic Aci | 2014 |
[1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus].
Topics: Alanine; Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Chronic Disease; Depressio | 2014 |
A pilot study investigating lactic acid bacterial symbionts from the honeybee in inhibiting human chronic wound pathogens.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Infective Agents; Antibiosis; Bacteria; Bees; Biologic | 2016 |
Intramuscular pain modulatory substances before and after exercise in women with chronic neck pain.
Topics: Adult; beta-Endorphin; Chronic Disease; Exercise Therapy; Female; Glutamic Acid; Humans; Hydrocortis | 2015 |
Treatment of Staphylococcus aureus-induced chronic osteomyelitis with bone-like hydroxyapatite/poly amino acid loaded with rifapentine microspheres.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Chronic Disease; Delayed-Action Preparations; Drug Carr | 2015 |
Cardiac autonomic dysfunction in chronic stroke women is attenuated after submaximal exercise test, as evaluated by linear and nonlinear analysis.
Topics: Aged; Blood Glucose; Blood Pressure; Chronic Disease; Exercise Test; Female; Follow-Up Studies; Hear | 2015 |
Derivation and Validation of Predictive Factors for Clinical Deterioration after Admission in Emergency Department Patients Presenting with Abnormal Vital Signs Without Shock.
Topics: Aged; Bicarbonates; Chronic Disease; Disease Progression; Emergency Service, Hospital; Health Status | 2015 |
Late gadolinium enhancement on cardiac magnetic resonance predicts coronary vasomotor abnormality and myocardial lactate production in patients with chronic heart failure.
Topics: Acetylcholine; Adult; Aged; Biomarkers; Blood Flow Velocity; Cardiomyopathies; Chi-Square Distributi | 2016 |
Large Porous Particles for Sustained Release of a Decoy Oligonucelotide and Poly(ethylenimine): Potential for Combined Therapy of Chronic Pseudomonas aeruginosa Lung Infections.
Topics: Animals; Chronic Disease; Drug Carriers; Humans; Lactic Acid; Male; Oligonucleotides; Polyethyleneim | 2016 |
Association between the lactate/albumin ratio and mortality in pediatric septic shock patients with underlying chronic disease: retrospective pilot study.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Female; Hospital Mortality; Humans; Infant; La | 2021 |
Development and validation of the new ICNARC model for prediction of acute hospital mortality in adult critical care.
Topics: Adult; Age Factors; Aged; Blood Glucose; Cardiopulmonary Resuscitation; Chronic Disease; Creatinine; | 2017 |
Exercise responses in patients with chronically high creatine kinase levels.
Topics: Adult; Ammonia; Chronic Disease; Creatine Kinase; Exercise; Exercise Test; Female; Humans; Lactic Ac | 2017 |
Magnetic Resonance Spectroscopy for Evaluating Portal-Systemic Encephalopathy in Patients with Chronic Hepatic Schistosomiasis Japonicum.
Topics: Aged; Aged, 80 and over; Ammonia; Brain; Chronic Disease; Female; Globus Pallidus; Glutamine; Hepati | 2016 |
Thermoregulatory and metabolic responses of Japanese quail to hypoxia.
Topics: Acclimatization; Animals; Body Temperature Regulation; Chronic Disease; Coturnix; Hypercapnia; Hypox | 2008 |
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Stud | 2008 |
Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne.
Topics: Acne Vulgaris; Chronic Disease; Cicatrix; Esthetics; Female; Humans; Injections, Intradermal; Lactic | 2009 |
Delayed anatomical repair of ruptured ulnar collateral ligament injuries of the thumb using a dissolvable polylactic acid bone anchor.
Topics: Absorbable Implants; Adult; Chronic Disease; Collateral Ligaments; Humans; Joint Dislocations; Lacti | 2008 |
Transient postprandial ischemia is associated with increased intestinal fatty acid binding protein in patients with chronic gastrointestinal ischemia.
Topics: Adult; Aged; Biomarkers; Chronic Disease; Exercise Test; Fatty Acid-Binding Proteins; Female; Gastro | 2009 |
Frequency of mitochondrial defects in patients with chronic intestinal pseudo-obstruction.
Topics: Adolescent; Adult; Aged; Biopsy; Child; Child, Preschool; Chronic Disease; Clinical Enzyme Tests; DN | 2009 |
Development of animal model for calcified chronic total occlusion.
Topics: Animals; Apatites; Arterial Occlusive Diseases; Calcinosis; Chronic Disease; Coated Materials, Bioco | 2009 |
Reductions in mitochondrial O(2) consumption and preservation of high-energy phosphate levels after simulated ischemia in chronic hibernating myocardium.
Topics: Adenosine Triphosphate; Animals; Chronic Disease; Coronary Circulation; Coronary Occlusion; Coronary | 2009 |
Oligonucleotide decoy to NF-kappaB slowly released from PLGA microspheres reduces chronic inflammation in rat.
Topics: Animals; Blotting, Western; Chronic Disease; Disease Models, Animal; Drug Carriers; Electrophoretic | 2009 |
Frequent ejaculation associated free radical and lactic acid accumulation cause noninfectious inflammation and muscle dysfunction: a potential mechanism for symptoms in Chronic Prostatitis/Chronic Pelvic Pain Syndrome.
Topics: Chronic Disease; Ejaculation; Free Radicals; Humans; Lactic Acid; Male; Models, Immunological; Myosi | 2009 |
Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia.
Topics: Animals; Animals, Newborn; Brain Chemistry; Chronic Disease; Energy Metabolism; Glucose; Glutamic Ac | 2010 |
Transplantation of nanostructured composite scaffolds results in the regeneration of chronically injured spinal cords.
Topics: Amino Acid Sequence; Animals; Chronic Disease; Electrophysiological Phenomena; Female; Guided Tissue | 2011 |
Quantification of cerebrospinal fluid lactic acid in the differential diagnosis between HIV chronic meningitis and opportunistic meningitis.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Biomarkers; Child; Child, Preschool; Chron | 2011 |
Chronic stress and carbohydrate metabolism: persistent changes and slow return to normalcy in male albino rats.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Blood Glucose; Body Weight; Carbohydrate M | 2012 |
Reliable porcine coronary model of chronic total occlusion using copper wire stents and bioabsorbable levo-polylactic acid polymer.
Topics: Animals; Biocompatible Materials; Chronic Disease; Copper; Coronary Occlusion; Coronary Vessels; Dis | 2012 |
Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetone; Adult; Alcoholism; Blood Glucose; Chronic Disease; Human | 2013 |
Efferent projections of neuropeptide Y-expressing neurons of the dorsomedial hypothalamus in chronic hyperphagic models.
Topics: Age Factors; Animals; Animals, Newborn; Biotin; Chronic Disease; Dextrans; Disease Models, Animal; E | 2013 |
Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure.
Topics: Acetanilides; Animals; Cardiotonic Agents; Chronic Disease; Coronary Circulation; Disease Models, An | 2002 |
High intratendinous lactate levels in painful chronic Achilles tendinosis. An investigation using microdialysis technique.
Topics: Achilles Tendon; Adult; Animals; Chronic Disease; Humans; Lactic Acid; Male; Microdialysis; Middle A | 2002 |
Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Adaptation, Physiological; Animals; Blood-Brain Barrier; Brain | 2002 |
Comparison between the effects of chronic and acute hypoxemia on muscle afferent activities from the tibialis anterior muscle.
Topics: Action Potentials; Afferent Pathways; Animals; Chronic Disease; Electric Stimulation; Evoked Potenti | 2003 |
Guided tissue regeneration using a polylactic acid barrier.
Topics: Adolescent; Adult; Aged; Alveolar Bone Loss; Alveolar Process; Bacteroidaceae Infections; Chronic Di | 2003 |
The development of myocardial insulin resistance in conscious dogs with advanced dilated cardiomyopathy.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cardiac Pacing, Artificial; Cardiomyopathy, Dila | 2004 |
Influence of chronic hypoxemia on peripheral muscle function and oxidative stress in humans.
Topics: Aged; Chronic Disease; Electromyography; Evoked Potentials; Female; Glutathione; Humans; Hypoxia; La | 2004 |
3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Topics: Acute Disease; Animals; Behavior, Animal; Body Weight; Brain; Choline; Chronic Disease; Disease Mode | 2004 |
Studies on intragastric PCO2 at rest and during exercise as a marker of intestinal perfusion in patients with chronic heart failure.
Topics: Biomarkers; Carbon Dioxide; Chronic Disease; Exercise; Exercise Test; Female; Germany; Heart Failure | 2004 |
An in-vivo model to interrogate the transition from acute to chronic inflammation.
Topics: Absorbable Implants; Acute Disease; Animals; Calcium Phosphates; Chronic Disease; Coated Materials, | 2004 |
Atopic dermatitis, stinging, and effects of chronic stress: a pathocausal study.
Topics: Adult; Chronic Disease; Cosmetics; Dermatitis, Atopic; Female; Humans; Hydrocortisone; Lactic Acid; | 2004 |
Adaptation to chronic hypoxia during diet-induced ketosis.
Topics: Adaptation, Physiological; Animals; Chronic Disease; Diet; Glucose; Glycolysis; Hypoxia, Brain; Keto | 2005 |
Biochemical alterations in the trapezius muscle of patients with chronic whiplash associated disorders (WAD)--a microdialysis study.
Topics: Adult; Chronic Disease; Exercise; Female; Glutamic Acid; Humans; Interleukin-6; Lactic Acid; Microdi | 2008 |
Evaluation of cellular organization and axonal regeneration through linear PLA foam implants in acute and chronic spinal cord injury.
Topics: Acute Disease; Animals; Axons; Biocompatible Materials; Calcitonin Gene-Related Peptide; Chronic Dis | 2007 |
Effects of high-intensity training on MCT1, MCT4, and NBC expressions in rat skeletal muscles: influence of chronic metabolic alkalosis.
Topics: Alkalosis; Animals; Chronic Disease; Citrate (si)-Synthase; Lactic Acid; Male; Monocarboxylic Acid T | 2007 |
Sodium fusidate-poly(D,L-lactide-co-glycolide) microspheres: preparation, characterisation and in vivo evaluation of their effectiveness in the treatment of chronic osteomyelitis.
Topics: Animals; Calorimetry, Differential Scanning; Chronic Disease; Drug Carriers; Fusidic Acid; Lactic Ac | 2007 |
Discrimination of metabolic profiles of pancreatic cancer from chronic pancreatitis by high-resolution magic angle spinning 1H nuclear magnetic resonance and principal components analysis.
Topics: Animals; Choline; Chronic Disease; Diagnosis, Differential; Disease Models, Animal; Lactic Acid; Lip | 2007 |
Metabolic acidosis decreases fetal myocardial isovolumic velocities in a chronic sheep model of increased placental vascular resistance.
Topics: Acidosis; Acute Disease; Animals; Blood Pressure; Cardiac Output; Central Venous Pressure; Chronic D | 2008 |
Myocardial metabolic and hemodynamic effects of intravenous MDL-17,043, a new cardiotonic drug, in patients with chronic severe heart failure.
Topics: Aged; Blood Flow Velocity; Cardiotonic Agents; Chronic Disease; Enoximone; Female; Heart Failure; He | 1984 |
Intramuscular pressure, blood flow, and skeletal muscle metabolism in patients with venous claudication.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Blood Pressure; Chronic Disease; Female; Humans; Il | 1984 |
Two forms of biotin-responsive multiple carboxylase deficiency.
Topics: Acute Disease; Biotin; Carbon-Carbon Ligases; Chronic Disease; Fibroblasts; Humans; Hydroxy Acids; I | 1981 |
[Acid-base disturbance in patients with compensated liver cirrhosis and chronic hepatitis (author's transl)].
Topics: Acid-Base Imbalance; Adult; Carbon Dioxide; Chronic Disease; Female; Hepatitis; Humans; Lactates; La | 1981 |
Increased organ blood flow in chronic endotoxemia is reversed by nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiac Output; Chronic Disease; Esch | 1994 |
Effects of chronic iron deficiency anemia on brain metabolism.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Anemia, Iron-Deficiency; Animals; Blood Glucose; Body Weight; Brai | 1995 |
Renal function during chronic anemia in the ovine fetus.
Topics: Amniotic Fluid; Anemia; Animals; Biological Availability; Chronic Disease; Fetal Diseases; Fetus; Gl | 1994 |
Cerebral cortex ammonia and glutamine metabolism in two rat models of chronic liver insufficiency-induced hyperammonemia: influence of pair-feeding.
Topics: Amino Acids; Ammonia; Animals; Behavior, Animal; Bile Ducts; Cerebral Cortex; Chronic Disease; Eatin | 1993 |
Fatigue and exhaustion in chronic hypobaric hypoxia: influence of exercising muscle mass.
Topics: Adult; Altitude; Chronic Disease; Electromyography; Fatigue; Forearm; Humans; Hypoxia; Lactates; Lac | 1994 |
Effects of chronic hypercortisolemia on carbohydrate metabolism during insulin deficiency.
Topics: Alanine; Animals; Blood Glucose; Carbohydrate Metabolism; Catecholamines; Chronic Disease; Dogs; Glu | 1994 |
Cerebral metabolism and electrocortical activity in the chronically hyperglycemic fetal lamb.
Topics: Animals; Arteries; Blood Glucose; Brain; Cerebral Cortex; Chronic Disease; Electroencephalography; F | 1993 |
Effect of chronic uraemia on skeletal muscle metabolism in man.
Topics: Adenosine Triphosphate; Aged; Anemia; Chronic Disease; Energy Metabolism; Exercise; Humans; Hydrogen | 1993 |
Peak skeletal muscle perfusion is maintained in patients with chronic heart failure when only a small muscle mass is exercised.
Topics: Cardiac Output; Cardiomyopathy, Dilated; Chronic Disease; Exercise; Female; Humans; Lactic Acid; Leg | 1997 |
Chronic hypoxia, glutathione-dependent detoxication, and metabolic instability in rat small intestine.
Topics: Animals; Cell Survival; Chronic Disease; Fructose; Glutathione; Hypoxia; Ileum; Inactivation, Metabo | 1997 |
Metabolic and neurological patterns in chronic cerebral infarction: a single-voxel 1H-MR spectroscopy study.
Topics: Adult; Aged; Aged, 80 and over; Cerebral Infarction; Chronic Disease; Dominance, Cerebral; Energy Me | 1997 |
Non-invasive measurement of cardiac output and ventricular ejection fractions in chronic cardiac failure: relationship to impaired exercise tolerance.
Topics: Adult; Aged; Cardiac Output; Chronic Disease; Exercise Test; Exercise Tolerance; Heart Failure; Hear | 1997 |
Skeletal muscle function at low work level as a model for daily activities in patients with chronic heart failure.
Topics: Activities of Daily Living; Blood Flow Velocity; Blood Gas Analysis; Chronic Disease; Energy Metabol | 1997 |
Glucose metabolism in chronic diabetic foot ulcers measured in vivo using microdialysis.
Topics: Aged; Blood Glucose; Chronic Disease; Diabetic Foot; Female; Foot; Glucose; Humans; Lactic Acid; Mal | 1998 |
In vivo 1H MR spectroscopic imaging and diffusion weighted MRI in experimental hydrocephalus.
Topics: Acute Disease; Analysis of Variance; Animals; Brain; Brain Edema; Brain Ischemia; Chronic Disease; D | 1998 |
Female-related skeletal muscle phenotype in patients with moderate chronic heart failure before and after dynamic exercise training.
Topics: Adult; Aged; Biopsy, Needle; Case-Control Studies; Chronic Disease; Exercise Test; Female; Heart Fai | 1999 |
Exertional myalgia syndrome associated with diminished serum ammonia elevation in ischemic exercise testing.
Topics: Adult; Ammonia; AMP Deaminase; Biopsy; Chronic Disease; Exercise Test; Humans; Lactic Acid; Male; Mu | 1999 |
Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Anxiety; Aspartic Acid; Back Pain; Brain Chemistry; Choline; Chronic Disease; Creatine; Femal | 2000 |
The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex.
Topics: Acute Disease; Amino Acids; Animals; Blood Glucose; Brain Ischemia; Cerebral Cortex; Chronic Disease | 2001 |
The effects of topical alpha-hydroxyacids on the normal skin barrier of hairless mice.
Topics: Animals; Chronic Disease; Epidermis; Galvanic Skin Response; Glycolates; Keratolytic Agents; Lactic | 2001 |
Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy.
Topics: Acidosis, Lactic; Adult; Antiretroviral Therapy, Highly Active; Chronic Disease; Data Interpretation | 2001 |
Preparation and evaluation of poly(L-lactic acid) microspheres containing rhEGF for chronic gastric ulcer healing.
Topics: Animals; Chronic Disease; Epidermal Growth Factor; Lactic Acid; Male; Microscopy, Electron, Scanning | 2001 |
Chronic hypoxia: a model for cyanotic congenital heart defects.
Topics: Adenosine Triphosphate; Animals; Cardiopulmonary Bypass; Chronic Disease; Cyanosis; Disease Models, | 2002 |
Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control.
Topics: Aged; Aspirin; Bradykinin; Chemoreceptor Cells; Chronic Disease; Cyclooxygenase Inhibitors; Exercise | 2002 |
[Intestinal calcium absorption in hypertension patients].
Topics: Adult; Calcitonin; Calcitriol; Calcium; Chronic Disease; Creatinine; Humans; Hypertension; Intestina | 1992 |
Muscle ATP and lactate and the release of myoglobin and carbanhydrase III in acute lower-limb ischaemia.
Topics: Acute Disease; Adenosine Triphosphate; Aged; Aged, 80 and over; Blood Vessel Prosthesis; Carbonic An | 1991 |
Chronic maxillary sinusitis. Energy metabolism in sinus mucosa and secretion.
Topics: Adenine Nucleotides; Chronic Disease; Energy Metabolism; Glucose; Humans; Lactates; Lactic Acid; Leu | 1991 |
Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure.
Topics: Adenosine Triphosphate; Adult; Aged; Chronic Disease; Exercise Test; Female; Glycolysis; Heart Failu | 1990 |
The value of umbilical blood 2,3 diphosphoglycerate levels in the diagnosis of chronic fetal hypoxia.
Topics: 2,3-Diphosphoglycerate; Chronic Disease; Diphosphoglyceric Acids; Erythrocytes; Female; Fetal Blood; | 1990 |
Substrate alterations in a sarcoma-bearing rat model: effect of tumor growth and resection.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Body Weight; Cholesterol; Chronic Dise | 1990 |
Effect of chronic ischemia on glucose metabolism of rabbit urinary bladder.
Topics: Animals; Carbon Dioxide; Chronic Disease; Glucose; Ischemia; Lactates; Lactic Acid; Rabbits; Urinary | 1989 |
[Significance of anaerobic threshold in the assessment of functional state in patients with chronic heart disease].
Topics: Adult; Anaerobic Threshold; Chronic Disease; Exercise Test; Female; Heart Diseases; Humans; Lactates | 1989 |
Renal tubular biochemistry during acute and chronic metabolic alkalosis in the dog.
Topics: Acute Disease; Alkalosis; Ammonia; Animals; Chronic Disease; Citrates; Citric Acid; Cytosol; Dogs; G | 1985 |
[Panic attacks in adolescents].
Topics: Acute Disease; Adolescent; Antidepressive Agents, Tricyclic; Anxiety Disorders; Chronic Disease; Dia | 1985 |
Impaired left ventricular postischemic function and metabolism in chronic right ventricular hypertrophy.
Topics: Adenosine Triphosphate; Animals; Cardiac Volume; Cardiomegaly; Chronic Disease; Coronary Circulation | 1987 |
[Tissue respiration in chronic bronchitis].
Topics: Adult; Bronchitis; Chronic Disease; Electron Transport Complex IV; Female; Humans; L-Lactate Dehydro | 1986 |
[Assessment of the calcium homeostatic state using the double calcium tolerance test].
Topics: Calcium; Calcium, Dietary; Chronic Disease; Feedback; Heart Failure; Homeostasis; Humans; Hypercalce | 1988 |
[Post-fructose increase in the blood level of lactic acid in various pathologic conditions].
Topics: Aged; Bronchitis; Chronic Disease; Diabetes Mellitus; Female; Fructose; Humans; Infusions, Intraveno | 1987 |
Myocardial substrate utilization and amino acid metabolism in chronic coronary artery disease.
Topics: Amino Acids; Cardiac Pacing, Artificial; Chronic Disease; Coronary Disease; Fatty Acids, Nonesterifi | 1987 |
Effect of acetazolamide on renal metabolism and ammoniagenesis in the dog.
Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Chronic Disease; Citrates; Citric Acid; Dogs; G | 1987 |
[Studies of muscle metabolism in chronic major limb arterial occlusive disease patients by unilateral ergometric lower leg stress (III)].
Topics: Adult; Aged; Arterial Occlusive Diseases; Chronic Disease; Energy Metabolism; Exercise Test; Humans; | 1985 |
[Diagnostic significance of determining the blood content of lactic and uric acids in chronic liver lesions of alcoholic and viral etiologies].
Topics: Adult; Chronic Disease; Female; Hepatitis, Alcoholic; Hepatitis, Chronic; Humans; Lactates; Lactic A | 1985 |