lactic acid has been researched along with Chronic Hepatitis C in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ribavirin is an antiviral drug used for the treatment of chronic hepatitis C." | 3.80 | Development of biodegradable nanoparticles for liver-specific ribavirin delivery. ( Ishihara, T; Kaneko, K; Mizushima, T, 2014) |
| " Pharmacokinetic curves were recorded at steady-state." | 2.84 | Metformin and daclatasvir: absence of a pharmacokinetic-pharmacodynamic drug interaction in healthy volunteers. ( Aarnoutse, RE; Burger, DM; Colbers, A; de Kanter, CTMM; Drenth, JPH; Smolders, EJ; Tack, CJ; van Ewijk-Beneken Kolmer, N; Velthoven-Graafland, K; Wolberink, LT, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smolders, EJ | 1 |
| Colbers, A | 1 |
| de Kanter, CTMM | 1 |
| Velthoven-Graafland, K | 1 |
| Wolberink, LT | 1 |
| van Ewijk-Beneken Kolmer, N | 1 |
| Drenth, JPH | 1 |
| Aarnoutse, RE | 1 |
| Tack, CJ | 1 |
| Burger, DM | 1 |
| Ishihara, T | 2 |
| Kaneko, K | 1 |
| Mizushima, T | 1 |
| Walker, UA | 1 |
| Bäuerle, J | 1 |
| Laguno, M | 1 |
| Murillas, J | 1 |
| Mauss, S | 1 |
| Schmutz, G | 1 |
| Setzer, B | 1 |
| Miquel, R | 1 |
| Gatell, JM | 1 |
| Mallolas, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Drug-drug Interaction Study Between the Novel Anti-hepatitis c Virus (HCV) Agent Daclatasvir and The Antidiabetic Agent Metformin in Healthy Volunteers[NCT02565862] | Phase 1 | 20 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lactic acid and Chronic Hepatitis C
| Article | Year |
|---|---|
Metformin and daclatasvir: absence of a pharmacokinetic-pharmacodynamic drug interaction in healthy volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Blood Glucose; Carbamates; Cross-Over Studies; Diabet | 2017 |
2 other studies available for lactic acid and Chronic Hepatitis C
| Article | Year |
|---|---|
Development of biodegradable nanoparticles for liver-specific ribavirin delivery.
Topics: Animals; Antiviral Agents; Biocompatible Materials; Cell Line, Tumor; Delayed-Action Preparations; D | 2014 |
Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine.
Topics: Acidosis, Lactic; Adult; Cross-Sectional Studies; Didanosine; DNA, Mitochondrial; Female; Hepatitis | 2004 |