Page last updated: 2024-10-17

lactic acid and Chlamydia Infections

lactic acid has been researched along with Chlamydia Infections in 4 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Chlamydia Infections: Infections with bacteria of the genus CHLAMYDIA.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Edwards, VL1
Smith, SB1
McComb, EJ1
Tamarelle, J1
Ma, B1
Humphrys, MS1
Gajer, P1
Gwilliam, K1
Schaefer, AM1
Lai, SK1
Terplan, M1
Mark, KS1
Brotman, RM1
Forney, LJ1
Bavoil, PM1
Ravel, J1
Chappell, BT1
Mena, LA1
Maximos, B1
Mollan, S1
Culwell, K1
Howard, B1
Bharatwaj, B1
Wu, L1
Whittum-Hudson, JA2
da Rocha, SR1
Toti, US1
Guru, BR1
Hali, M1
McPharlin, CM1
Wykes, SM1
Panyam, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2B Double-blind Placebo-controlled Efficacy Trial of EVO100 (Previously Known as Amphora ® Gel) for the Prevention of Acquisition of Urogenital Chlamydia Trachomatis Infection[NCT03107377]Phase 2/Phase 3860 participants (Actual)Interventional2017-11-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Compliance With EVO100 and Sensitivity Analyses (Part I)

Summary of Coital Events during treatment (NCT03107377)
Timeframe: 16 weeks

InterventionCoital Events (Mean)
EVO10015.7
Placebo16.3

Compliance With EVO100 and Sensitivity Analyses (Part II)

Summary of number of applicators used via eDiary (NCT03107377)
Timeframe: 16 weeks

InterventionNumber of Applicators (Mean)
EVO10013.0
Placebo13.5

Compliance With EVO100 and Sensitivity Analyses (Part III)

Study product adherence (NCT03107377)
Timeframe: 16 weeks

Intervention% of sex acts where study product used (Mean)
EVO10078.9
Placebo78.3

Urogenital CT Infection

Proportion of subjects who experience urogenital CT infection during the study intervention period (incident infection of CT). (NCT03107377)
Timeframe: 16 weeks

InterventionParticipants (Count of Participants)
EVO10014
Placebo28

Urogenital GC Infection

Proportion of subjects who experience urogenital GC infection during the study intervention period (incident infection of GC). (NCT03107377)
Timeframe: 16 weeks

InterventionParticipants (Count of Participants)
EVO1002
Placebo9

Trials

1 trial available for lactic acid and Chlamydia Infections

ArticleYear
EVO100 prevents chlamydia and gonorrhea in women at high risk of infection.
    American journal of obstetrics and gynecology, 2021, Volume: 225, Issue:2

    Topics: Administration, Intravaginal; Adult; Anti-Infective Agents; Chlamydia Infections; Citric Acid; Drug

2021

Other Studies

3 other studies available for lactic acid and Chlamydia Infections

ArticleYear
The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection.
    mBio, 2019, 08-13, Volume: 10, Issue:4

    Topics: Cell Movement; Cell Proliferation; Cervix Uteri; Chlamydia Infections; Chlamydia trachomatis; Female

2019
The potential for the noninvasive delivery of polymeric nanocarriers using propellant-based inhalers in the treatment of Chlamydial respiratory infections.
    Biomaterials, 2010, Volume: 31, Issue:28

    Topics: Aerosol Propellants; Aerosols; Anti-Bacterial Agents; Cell Line; Chlamydia; Chlamydia Infections; Co

2010
Targeted delivery of antibiotics to intracellular chlamydial infections using PLGA nanoparticles.
    Biomaterials, 2011, Volume: 32, Issue:27

    Topics: Anti-Bacterial Agents; Azithromycin; Cell Line; Chemistry, Pharmaceutical; Chlamydia Infections; Chl

2011