lactic acid has been researched along with Child Development Deviations in 17 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyruvate dehydrogenase (PDH) deficiency is a major cause of primary lactic acidosis and neurological dysfunction in infancy and early childhood." | 3.78 | Unilateral periventricular leukomalacia in association with pyruvate dehydrogenase deficiency. ( Connolly, DJ; Mordekar, SR; Sharma, R; Sharrard, MJ, 2012) |
| "Hypoxic-ischemic encephalopathy did not develop in any of the normal newborns but did develop in 16 of the 40 newborns with asphyxia." | 1.30 | Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. ( Chang, YC; Huang, CC; Lin, KP; Wang, ST; Wu, PL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Peng, B | 1 |
| Hou, C | 1 |
| Li, J | 1 |
| Zeng, Y | 1 |
| Wu, W | 1 |
| Liao, Y | 1 |
| Tian, Y | 1 |
| Chen, WX | 1 |
| Mitra, S | 1 |
| Bale, G | 1 |
| Highton, D | 1 |
| Gunny, R | 1 |
| Uria-Avellanal, C | 1 |
| Bainbridge, A | 1 |
| Sokolska, M | 1 |
| Price, D | 1 |
| Huertas-Ceballos, A | 1 |
| Kendall, GS | 1 |
| Meek, J | 1 |
| Tachtsidis, I | 1 |
| Robertson, NJ | 1 |
| Wiberg, N | 1 |
| Klausen, TW | 1 |
| Tyrberg, T | 1 |
| Nordström, L | 1 |
| Wiberg-Itzel, E | 1 |
| Liu, L | 1 |
| Zheng, CX | 1 |
| Peng, SF | 1 |
| Zhou, HY | 1 |
| Su, ZY | 1 |
| He, L | 1 |
| Ai, T | 1 |
| Verity, CM | 1 |
| Winstone, AM | 1 |
| Stellitano, L | 1 |
| Krishnakumar, D | 1 |
| Will, R | 1 |
| McFarland, R | 1 |
| Verheijen, PM | 1 |
| Lisowski, LA | 1 |
| Wassink, S | 1 |
| Visser, GH | 1 |
| Meijboom, EJ | 1 |
| Bennet, L | 1 |
| Booth, L | 1 |
| Gunn, AJ | 1 |
| Friedman, SD | 1 |
| Shaw, DW | 1 |
| Ishak, G | 1 |
| Gropman, AL | 1 |
| Saneto, RP | 1 |
| Sharma, R | 1 |
| Sharrard, MJ | 1 |
| Connolly, DJ | 1 |
| Mordekar, SR | 1 |
| Mackie, AS | 1 |
| Alton, GY | 1 |
| Dinu, IA | 1 |
| Joffe, AR | 1 |
| Roth, SJ | 1 |
| Newburger, JW | 1 |
| Robertson, CM | 2 |
| Terek, D | 1 |
| Koroglu, O | 1 |
| Yalaz, M | 1 |
| Gokben, S | 1 |
| Calli, C | 1 |
| Coker, M | 1 |
| Kultursay, N | 1 |
| Fuloria, M | 1 |
| Funk, MJ | 1 |
| Belinson, SE | 1 |
| Pimenta, JM | 1 |
| Morsheimer, M | 1 |
| Gibbons, DC | 1 |
| Cheung, PY | 1 |
| Finer, NN | 1 |
| Huang, CC | 1 |
| Wang, ST | 1 |
| Chang, YC | 1 |
| Lin, KP | 1 |
| Wu, PL | 1 |
| Barkovich, AJ | 1 |
| Baranski, K | 1 |
| Vigneron, D | 1 |
| Partridge, JC | 1 |
| Hallam, DK | 1 |
| Hajnal, BL | 1 |
| Ferriero, DM | 1 |
| Pearl, PL | 1 |
| Krasnewich, D | 1 |
3 reviews available for lactic acid and Child Development Deviations
| Article | Year |
|---|---|
Potential biomarkers for hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Creatinine; Developmental Disabilities; Humans; Hypothermia, Induce | 2010 |
The use of neuroimaging in the diagnosis of mitochondrial disease.
Topics: Adenosine Triphosphate; Aspartic Acid; Brain; Child; Developmental Disabilities; Diagnosis, Differen | 2010 |
Mitochondrial disorders among infants exposed to HIV and antiretroviral therapy.
Topics: Anemia; Animals; Anti-HIV Agents; Blood Cell Count; Developmental Disabilities; DNA, Mitochondrial; | 2007 |
14 other studies available for lactic acid and Child Development Deviations
| Article | Year |
|---|---|
Novel compound heterozygous TARS2 variants in a Chinese family with mitochondrial encephalomyopathy: a case report.
Topics: Asian People; Developmental Disabilities; Epilepsy; Family; Gene Expression; Heterozygote; High-Thro | 2020 |
Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury.
Topics: Adenosine Triphosphate; Aspartic Acid; Blood Pressure; Brain; Cerebrovascular Circulation; Developme | 2019 |
Infant outcome at four years of age after intrapartum sampling of scalp blood lactate for fetal assessment. A cohort study.
Topics: Child, Preschool; Developmental Disabilities; Female; Fetal Blood; Fetal Distress; Fetal Monitoring; | 2018 |
Evaluation of urinary S100B protein level and lactate/creatinine ratio for early diagnosis and prognostic prediction of neonatal hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Child Development; Creatinine; Developmental Disabilities; Humans; | 2010 |
The clinical presentation of mitochondrial diseases in children with progressive intellectual and neurological deterioration: a national, prospective, population-based study.
Topics: Adolescent; Basal Ganglia; Child; Child, Preschool; Developmental Disabilities; Diagnosis, Different | 2010 |
Preoperative acidosis and infant development following surgery for congenital heart disease.
Topics: Acidosis, Lactic; Cardiopulmonary Bypass; Cohort Studies; Developmental Disabilities; Heart Arrest, | 2010 |
Unilateral periventricular leukomalacia in association with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Alleles; Cerebral Ventricles; Developmental Disabilities; Diagnosis, Differential; | 2012 |
Clinical outcome score predicts the need for neurodevelopmental intervention after infant heart surgery.
Topics: Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Chi-Square Dist | 2013 |
Diagnostic tools of early brain disturbances in an asymptomatic neonate with maple syrup urine disease.
Topics: Aspartic Acid; Brain Diseases; Brain Waves; Consanguinity; Developmental Disabilities; Diet; Diet, C | 2013 |
Elevated plasma lactate levels: a tool for predicting outcomes or for improving care.
Topics: Critical Care; Developmental Disabilities; Extracorporeal Membrane Oxygenation; Humans; Infant, Newb | 2002 |
Plasma lactate as a predictor of early childhood neurodevelopmental outcome of neonates with severe hypoxaemia requiring extracorporeal membrane oxygenation.
Topics: Biomarkers; Developmental Disabilities; Extracorporeal Membrane Oxygenation; Humans; Hypoxia; Infant | 1996 |
Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Brain Ischemia; Creatinine; Developmental Disabilities; Fetal Hypox | 1999 |
Proton MR spectroscopy for the evaluation of brain injury in asphyxiated, term neonates.
Topics: Aspartic Acid; Asphyxia Neonatorum; Brain; Brain Damage, Chronic; Choline; Creatine; Developmental D | 1999 |
Neurologic course of congenital disorders of glycosylation.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Congenital Disorde | 2001 |