lactic acid has been researched along with Chemical and Drug Induced Liver Injury in 42 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Lactic acidosis and hepatic dysfunction improved." | 9.08 | Intravenous almitrine bismesylate reversibly induces lactic acidosis and hepatic dysfunction in patients with acute lung injury. ( B'chir, A; Losser, MR; Mebazaa, A; Payen, D; Romieu, M, 1998) |
| " We observed a patient with nonmetastatic breast cancer who died because of severe lactic acidosis (plasma lactate concentration = 27 mmol/l) after ingestion of 25 g of elemental germanium over a 2-months period." | 7.68 | Abuse of germanium associated with fatal lactic acidosis. ( Iten, PX; Krapf, R; Schaffner, T, 1992) |
| "The long-term effects of the sodium salt of dichloroacetic acid (DCA) were evaluated in four patients with mitochondrial encephalomyelopathy with lactic acidosis and stroke-like episodes (MELAS) carrying A3243G mutation." | 5.11 | Dichloroacetate treatment for mitochondrial cytopathy: long-term effects in MELAS. ( Goto, T; Momoi, MY; Mori, M; Saito, S; Yamagata, T, 2004) |
| " Lactic acidosis and hepatic dysfunction improved." | 5.08 | Intravenous almitrine bismesylate reversibly induces lactic acidosis and hepatic dysfunction in patients with acute lung injury. ( B'chir, A; Losser, MR; Mebazaa, A; Payen, D; Romieu, M, 1998) |
| "Clinical investigations suggest that hepatotoxicity after acetaminophen (APAP) overdose could be more severe in the context of obesity and nonalcoholic fatty liver disease." | 3.78 | Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice. ( Aubert, J; Begriche, K; Delannoy, M; Fromenty, B; Jaeschke, H; Lepage, S; Lucas-Clerc, C; McGill, MR; Morel, I; Pajaud, J; Ribault, C; Robin, MA; Turlin, B, 2012) |
| " mtDNA depletion may contribute to lactic acidosis, steatohepatitis and liver failure." | 3.71 | Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors. ( Setzer, B; Venhoff, N; Walker, UA, 2002) |
| " Lactic acidosis, characterized by metabolic acidosis, blood lactate above 5 mmol/l, hepatic steatosis and high mortality, represents the extreme end of this spectrum where there is complete decompensation." | 3.71 | Hyperlactatemia syndromes in people with HIV infection. ( John, M; Mallal, S, 2002) |
| "The mechanism of prolongation of sleeping (anesthesia) time after phenobarbital (PB) treatment was assessed in mice with ethionine (ET)-induced liver disorders (ET-treated group)." | 3.69 | Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice. ( Kawai, Y; Noguchi, M, 1996) |
| " We observed a patient with nonmetastatic breast cancer who died because of severe lactic acidosis (plasma lactate concentration = 27 mmol/l) after ingestion of 25 g of elemental germanium over a 2-months period." | 3.68 | Abuse of germanium associated with fatal lactic acidosis. ( Iten, PX; Krapf, R; Schaffner, T, 1992) |
| "Dinoseb is a highly toxic pesticide of the dinitrophenol group." | 1.46 | Distribution, lipid-bilayer affinity and kinetics of the metabolic effects of dinoseb in the liver. ( Bracht, A; Bracht, F; Bracht, L; de Sá-Nakanishi, AB; Parizotto, AV; Peralta, RM; Salla, GBF, 2017) |
| "Bupropion was included as structurally related drug used therapeutically." | 1.46 | Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. ( Krähenbühl, S; Liechti, ME; Luethi, D, 2017) |
| "Benzbromarone is an uricosuric structurally related to amiodarone and a known mitochondrial toxicant." | 1.40 | Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. ( Felser, A; Jenö, P; Krähenbühl, S; Kratschmar, DV; Lindinger, PW; Mies, S; Odermatt, A; Schnell, D, 2014) |
| "Acetaminophen-induced acute liver failure (ALF) is a complex multiorgan illness." | 1.38 | Comparison of the sequential organ failure assessment score with the King's College Hospital criteria and the model for end-stage liver disease score for the prognosis of acetaminophen-induced acute liver failure. ( Agarwal, B; Betrosian, A; Burroughs, AK; Cholongitas, E; O'Beirne, J; Patch, D; Shaw, S; Theocharidou, E; Vasianopoulou, P, 2012) |
| "Acetaminophen (APAP) is a commonly used and effective analgesic and antipyretic agent." | 1.38 | Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients. ( Hashimoto, T; Kobayashi, A; Kondo, K; Kuno, H; Shoda, T; Sugai, S; Suzuki, Y; Takahashi, A; Toyoda, K; Yamada, N, 2012) |
| "To improve the bioavailability of antitubercular drugs (ATDs) as well as to assess the feasibility of administering ATDs via the respiratory route, this study reports the formulation of three frontline ATDs, i." | 1.32 | Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis. ( Khuller, GK; Pandey, R; Prasad, B; Sharma, A; Sharma, S; Zahoor, A, 2003) |
| "Colchicine treatment produced a decrease in perivenular fibrosis and a descense in the degrees of this histological lesion." | 1.29 | Effect of colchicine on lactate production by isolated hepatocytes in rats treated with carbon tetrachloride and ethanol. ( Cutrín, C; Meniño, MJ; Parafita, MA, 1993) |
| " There was even a toxic response form the mixture at concentrations where the chemicals alone yielded no such response." | 1.27 | Assessment of the toxicity of chemical mixtures with isolated rat hepatocytes: cadmium and chloroform. ( Stacey, NH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (14.29) | 18.7374 |
| 1990's | 6 (14.29) | 18.2507 |
| 2000's | 12 (28.57) | 29.6817 |
| 2010's | 17 (40.48) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Haidar, MK | 1 |
| Morton, N | 1 |
| Roederer, T | 1 |
| Mayronne, S | 1 |
| Bawo, L | 1 |
| Kerkula, J | 1 |
| Porten, K | 1 |
| Baud, FJ | 1 |
| Salla, GBF | 1 |
| Bracht, L | 1 |
| de Sá-Nakanishi, AB | 1 |
| Parizotto, AV | 1 |
| Bracht, F | 1 |
| Peralta, RM | 2 |
| Bracht, A | 2 |
| Luethi, D | 1 |
| Liechti, ME | 1 |
| Krähenbühl, S | 2 |
| Soares, AA | 1 |
| de Oliveira, AL | 1 |
| Sá-Nakanishi, AB | 1 |
| Comar, JF | 1 |
| Rampazzo, AP | 1 |
| Vicentini, FA | 1 |
| Natali, MR | 1 |
| Gomes da Costa, SM | 1 |
| Paul, A | 1 |
| Das, J | 1 |
| Das, S | 4 |
| Samadder, A | 1 |
| Khuda-Bukhsh, AR | 1 |
| Felser, A | 1 |
| Lindinger, PW | 1 |
| Schnell, D | 1 |
| Kratschmar, DV | 1 |
| Odermatt, A | 1 |
| Mies, S | 1 |
| Jenö, P | 1 |
| Roy, P | 1 |
| Auddy, RG | 1 |
| Mukherjee, A | 1 |
| Toropova, AA | 1 |
| Nikolaev, SM | 1 |
| Razuvaeva, YG | 1 |
| Fedorov, AV | 1 |
| Sambueva, ZG | 1 |
| Ubeeva, IP | 1 |
| Pradhan, GK | 1 |
| Nath, D | 1 |
| Das Saha, K | 1 |
| Kim, GW | 1 |
| Oh, CH | 1 |
| Kim, JC | 1 |
| Yoon, W | 1 |
| Jeong, YY | 1 |
| Kim, YH | 1 |
| Kim, JK | 1 |
| Park, JG | 1 |
| Kang, HK | 1 |
| Jeong, GW | 1 |
| Chen, JH | 1 |
| Yu, GF | 1 |
| Jin, SY | 1 |
| Zhang, WH | 1 |
| Lei, DX | 1 |
| Zhou, SL | 1 |
| Song, XR | 1 |
| Lei, R | 1 |
| Wu, C | 1 |
| Yang, B | 1 |
| Ma, H | 1 |
| Shi, C | 1 |
| Wang, Q | 2 |
| Yuan, Y | 1 |
| Liao, M | 1 |
| Latif, IK | 1 |
| Karim, AJ | 1 |
| Zuki, AB | 1 |
| Zamri-Saad, M | 1 |
| Niu, JP | 1 |
| Noordin, MM | 1 |
| Fu, Q | 1 |
| Huang, X | 1 |
| Shu, B | 1 |
| Xue, M | 1 |
| Zhang, P | 1 |
| Wang, T | 1 |
| Liu, L | 1 |
| Jiang, Z | 1 |
| Zhang, L | 1 |
| Cholongitas, E | 1 |
| Theocharidou, E | 1 |
| Vasianopoulou, P | 1 |
| Betrosian, A | 1 |
| Shaw, S | 1 |
| Patch, D | 1 |
| O'Beirne, J | 1 |
| Agarwal, B | 1 |
| Burroughs, AK | 1 |
| Aubert, J | 1 |
| Begriche, K | 1 |
| Delannoy, M | 1 |
| Morel, I | 1 |
| Pajaud, J | 1 |
| Ribault, C | 1 |
| Lepage, S | 1 |
| McGill, MR | 1 |
| Lucas-Clerc, C | 1 |
| Turlin, B | 1 |
| Robin, MA | 1 |
| Jaeschke, H | 1 |
| Fromenty, B | 1 |
| Kondo, K | 1 |
| Yamada, N | 1 |
| Suzuki, Y | 1 |
| Toyoda, K | 1 |
| Hashimoto, T | 1 |
| Takahashi, A | 1 |
| Kobayashi, A | 1 |
| Shoda, T | 1 |
| Kuno, H | 1 |
| Sugai, S | 1 |
| Zouaoui, K | 1 |
| Dulaurent, S | 1 |
| Gaulier, JM | 1 |
| Moesch, C | 1 |
| Lachâtre, G | 1 |
| Walker, UA | 1 |
| Setzer, B | 1 |
| Venhoff, N | 1 |
| Batisse, D | 1 |
| Duong Van Huyen, JP | 1 |
| Piketty, C | 1 |
| Canali, GG | 1 |
| Karmochkine, M | 1 |
| Weiss, L | 1 |
| Bruneval, P | 1 |
| Kazatchkine, MD | 1 |
| Pandey, R | 1 |
| Sharma, A | 1 |
| Zahoor, A | 1 |
| Sharma, S | 1 |
| Khuller, GK | 1 |
| Prasad, B | 1 |
| Takahashi, H | 1 |
| Onishi, H | 1 |
| Machida, Y | 1 |
| Mori, M | 1 |
| Yamagata, T | 1 |
| Goto, T | 1 |
| Saito, S | 1 |
| Momoi, MY | 1 |
| Han, SY | 1 |
| Huh, CS | 1 |
| Ahn, YT | 1 |
| Lim, KS | 1 |
| Baek, YJ | 1 |
| Kim, DH | 1 |
| Tyagi, R | 1 |
| Lala, S | 1 |
| Verma, AK | 1 |
| Nandy, AK | 1 |
| Mahato, SB | 1 |
| Maitra, A | 1 |
| Basu, MK | 1 |
| da Silva Santos, NP | 1 |
| Nascimento, SC | 1 |
| Wanderley, MS | 1 |
| Pontes-Filho, NT | 1 |
| da Silva, JF | 1 |
| de Castro, CM | 1 |
| Pereira, EC | 1 |
| da Silva, NH | 1 |
| Honda, NK | 1 |
| Santos-Magalhães, NS | 1 |
| Liao, P | 1 |
| Wei, L | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Wu, H | 1 |
| Wu, Y | 1 |
| Ni, J | 1 |
| Pei, F | 1 |
| Paterson, KR | 1 |
| Paice, BJ | 1 |
| Lawson, DH | 1 |
| Santone, KS | 1 |
| Acosta, D | 1 |
| Bruckner, JV | 1 |
| Record, CO | 1 |
| Chase, RA | 1 |
| Williams, R | 1 |
| Appleton, D | 1 |
| Mokuda, O | 1 |
| Ubukata, E | 1 |
| Sakamoto, Y | 1 |
| Ozretić, B | 1 |
| Krajnović-Ozretić, M | 1 |
| Meniño, MJ | 1 |
| Cutrín, C | 1 |
| Parafita, MA | 1 |
| Noguchi, M | 1 |
| Kawai, Y | 1 |
| B'chir, A | 1 |
| Mebazaa, A | 1 |
| Losser, MR | 1 |
| Romieu, M | 1 |
| Payen, D | 1 |
| Hashida, M | 1 |
| Akamatsu, K | 1 |
| Nishikawa, M | 1 |
| Yamashita, F | 1 |
| Yoshikawa, H | 1 |
| Takakura, Y | 1 |
| John, M | 1 |
| Mallal, S | 1 |
| Krapf, R | 1 |
| Schaffner, T | 1 |
| Iten, PX | 1 |
| Takagi, D | 1 |
| Takeyama, N | 1 |
| Tanaka, T | 1 |
| Turnbull, DM | 1 |
| Dick, DJ | 1 |
| Wilson, L | 1 |
| Sherratt, HS | 1 |
| Alberti, KG | 1 |
| Stacey, NH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Almitrine and Severe COVID-19 Patients in ICU [Almitrine et Patients COVID-19 en Reanimation (French)][NCT04380727] | 17 participants (Actual) | Observational [Patient Registry] | 2020-03-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Undesired effects of biguanide therapy.
Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Drug Interact | 1984 |
2 trials available for lactic acid and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Dichloroacetate treatment for mitochondrial cytopathy: long-term effects in MELAS.
Topics: Abdominal Pain; Administration, Oral; Adolescent; Chemical and Drug Induced Liver Injury; Child; Dic | 2004 |
Intravenous almitrine bismesylate reversibly induces lactic acidosis and hepatic dysfunction in patients with acute lung injury.
Topics: Acidosis, Lactic; Acute Disease; Adolescent; Adult; Aged; Almitrine; Analysis of Variance; Bilirubin | 1998 |
39 other studies available for lactic acid and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Evaluating lactate prognostic value in children suspected of acetaminophen-induced liver failure in Liberia.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Hospital Mor | 2020 |
Distribution, lipid-bilayer affinity and kinetics of the metabolic effects of dinoseb in the liver.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Biological Transport; Chemical and Drug Induced | 2017 |
Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones.
Topics: Adenosine Triphosphate; Alkaloids; Benzodioxoles; Bupropion; Chemical and Drug Induced Liver Injury; | 2017 |
Effects of an Agaricus blazei aqueous extract pretreatment on paracetamol-induced brain and liver injury in rats.
Topics: Acetaminophen; Administration, Oral; Agaricus; Alanine; Animals; Antioxidants; Biomarkers; Brain; Br | 2013 |
Poly (lactide-co-glycolide) nano-encapsulation of chelidonine, an active bioingredient of greater celandine (Chelidonium majus), enhances its ameliorative potential against cadmium induced oxidative stress and hepatic injury in mice.
Topics: Algorithms; Animals; Benzophenanthridines; Cadmium Chloride; Cadmium Poisoning; Cell Survival; Cheli | 2013 |
Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzbromarone; Chemical and Drug Induced Liver Injury; D | 2014 |
Engineered andrographolide nanosystems for smart recovery in hepatotoxic conditions.
Topics: Andrographis; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; C | 2014 |
[Effect of Hypecoum erectum extract on morphofunctional state of the liver in rats with tetracycline-associated hepatitis].
Topics: Adenosine Triphosphate; Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Dru | 2014 |
Enhanced protective activity of nano formulated andrographolide against arsenic induced liver damage.
Topics: Animals; Antioxidants; Arsenic; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; C | 2015 |
Noninvasive biomarkers for acute hepatotoxicity induced by 1,3-dichloro-2-propanol: hyperpolarized 13C dynamic MR spectroscopy.
Topics: Alanine; Algorithms; alpha-Chlorohydrin; Animals; Biomarkers; Carbon-13 Magnetic Resonance Spectrosc | 2016 |
Activation of α2 adrenoceptor attenuates lipopolysaccharide-induced hepatic injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Alanine Transaminase; | 2015 |
Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: a rapid in vivo screening method for nanotoxicity.
Topics: Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Copper; Drug Evaluation, | 2008 |
Pulmonary modulation of benzo[a]pyrene-induced hemato- and hepatotoxicity in broilers.
Topics: Air Pollutants; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Be | 2010 |
Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury.
Topics: Animals; Cell Respiration; Chemical and Drug Induced Liver Injury; Diterpenes; Epoxy Compounds; Fatt | 2011 |
Comparison of the sequential organ failure assessment score with the King's College Hospital criteria and the model for end-stage liver disease score for the prognosis of acetaminophen-induced acute liver failure.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; APACHE; Biomarkers; Chemical and Drug Induced Liver | 2012 |
Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.
Topics: 3-Hydroxybutyric Acid; Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P- | 2012 |
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Glucose; | 2012 |
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro | 2013 |
Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors.
Topics: Acidosis, Lactic; Cell Line; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; DNA, Mitochon | 2002 |
Severe liver mitochondriopathy with normal liver histology and normal lactate levels in patients receiving nucleoside analogues.
Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Lactic Acid; Male; M | 2002 |
Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis.
Topics: Administration, Inhalation; Aerosols; Animals; Antibiotics, Antitubercular; Antitubercular Agents; A | 2003 |
Glycyrrhetic acid-loaded microparticles: liver-specific delivery and therapeutic potential against carbon tetrachloride-induced hepatitis.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Hig | 2004 |
Hepatoprotective effect of lactic acid bacteria, inhibitors of beta-glucuronidase production against intestinal microflora.
Topics: Animals; Bifidobacterium; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Co | 2005 |
Targeted delivery of arjunglucoside I using surface hydrophilic and hydrophobic nanocarriers to combat experimental leishmaniasis.
Topics: Animals; Antiparasitic Agents; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chemistr | 2005 |
Nanoencapsulation of usnic acid: An attempt to improve antitumour activity and reduce hepatotoxicity.
Topics: Animals; Benzofurans; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Disease Progression; | 2006 |
Metabolic profiling of serum from gadolinium chloride-treated rats by 1H NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Cr | 2007 |
Cadmium toxicity in primary cultures of rat hepatocytes.
Topics: Animals; Cadmium; Chemical and Drug Induced Liver Injury; L-Lactate Dehydrogenase; Lactates; Lactic | 1982 |
Disturbances of lactate metabolism in patients with liver damage due to paracetamol overdose.
Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Viral, Human; Human | 1981 |
Impaired glucose uptake and intact gluconeogenesis in perfused rat liver after carbon tetrachloride injury.
Topics: Animals; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gluconeogenesi | 1995 |
Plasma sorbitol dehydrogenase, glutamate dehydrogenase, and alkaline phosphatase as potential indicators of liver intoxication in grey mullet (Mugil auratus Risso).
Topics: Alkaline Phosphatase; Ammonia; Animals; Biomarkers; Carbon Tetrachloride Poisoning; Chemical and Dru | 1993 |
Effect of colchicine on lactate production by isolated hepatocytes in rats treated with carbon tetrachloride and ethanol.
Topics: Animals; Carbon Tetrachloride Poisoning; Cells, Cultured; Chemical and Drug Induced Liver Injury; Co | 1993 |
Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice.
Topics: Anesthesia; Anesthesia Recovery Period; Animals; Brain Chemistry; Carcinogens; Chemical and Drug Ind | 1996 |
Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting.
Topics: Acute Disease; Alprostadil; Animals; Biological Availability; Carbon Tetrachloride Poisoning; Chemic | 2000 |
Hyperlactatemia syndromes in people with HIV infection.
Topics: Acidosis, Lactic; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; HIV Infections; Homeostas | 2002 |
Abuse of germanium associated with fatal lactic acidosis.
Topics: Acidosis; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Female; Germanium; Hum | 1992 |
Biochemical effects of acute stress on energy metabolism in liver damaged rats.
Topics: Acetyl Coenzyme A; Animals; Chemical and Drug Induced Liver Injury; Cyclic AMP; Cyclic GMP; Energy M | 1987 |
Valproate causes metabolic disturbance in normal man.
Topics: Acetoacetates; Administration, Oral; Blood Glucose; Chemical and Drug Induced Liver Injury; Humans; | 1986 |
Assessment of the toxicity of chemical mixtures with isolated rat hepatocytes: cadmium and chloroform.
Topics: Animals; Aspartate Aminotransferases; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Chl | 1987 |