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lactic acid and Cerebral Palsy

lactic acid has been researched along with Cerebral Palsy in 14 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
" An increased lactate level was found in asphyctic infants and a clear correlation between lactic acidosis and foetal distress was documented."3.74Prevention of cerebral palsy during labour: role of foetal lactate. ( Borruto, F; Comparetto, C; Treisser, A, 2008)
" A decreased N-acetylaspartate/choline ratio, indicating neuronal injury, and an abnormally high lactate/N-acetylaspartate ratio were found only in the neonate with neonatal magnetic resonance imaging abnormalities and subsequent cerebral palsy."3.72Cerebral metabolism in severe neonatal hyperbilirubinemia. ( de Vries, LS; Groenendaal, F; van der Grond, J, 2004)
"Moderate to severe neonatal encephalopathy in asphyxiated term infants is associated with a high risk of cerebral palsy (especially quadriplegic or dyskinetic type) and/or cognitive disorders."2.44[Definition of intrapartum asphyxia and effects on outcome]. ( Zupan Simunek, V, 2008)
"Nineteen adolescents with spastic diplegia and 12 able-bodied controls took part in a longitudinal study of aerobic capacity and physical working capacity during their teens."1.27Longitudinal study of physical working capacity of young people with spastic cerebral palsy. ( Lundberg, A, 1984)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's7 (50.00)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Lundström, P1
Lauruschkus, K1
Andersson, Å1
Tornberg, ÅB1
Carbonne, B3
Pons, K1
Maisonneuve, E1
Salvador, AF1
Schubert, KR1
Cruz, RS1
Corvino, RB1
Pereira, KL1
Caputo, F1
de Oliveira, MF1
Gougeul, V1
Fekih, KM1
Groenendaal, F1
van der Grond, J1
de Vries, LS1
Cheung, PY1
Chui, N1
Joffe, AR1
Rebeyka, IM1
Robertson, CM1
Borruto, F1
Comparetto, C1
Treisser, A1
Nguyen, A1
Zupan Simunek, V1
Arús, C1
Bárány, M1
Westler, WM1
Markley, JL1
Lundberg, A1
Leth, H1
Toft, PB1
Peitersen, B1
Lou, HC1
Henriksen, O1
Pavlakis, SG1
Kingsley, PB1
Harper, R1
Buckwald, S1
Spinazzola, R1
Frank, Y1
Prohovnik, I1
Frøen, JF1
Munkeby, BH1
Stray-Pedersen, B1
Saugstad, OD1

Reviews

4 reviews available for lactic acid and Cerebral Palsy

ArticleYear
Foetal scalp blood sampling during labour for pH and lactate measurements.
    Best practice & research. Clinical obstetrics & gynaecology, 2016, Volume: 30

    Topics: Acidosis; Asphyxia Neonatorum; Blood Specimen Collection; Cerebral Palsy; Female; Fetal Blood; Fetal

2016
[Intrapartum fetal monitoring: old or new techniques?].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2003, Volume: 32, Issue:1 Suppl

    Topics: Cerebral Palsy; Electrocardiography; Female; Fetal Death; Fetal Hypoxia; Fetal Monitoring; Heart Rat

2003
[Fetal scalp blood sampling for pH and lactate measurement during labour].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2008, Volume: 37 Suppl 1

    Topics: Acidosis; Cerebral Palsy; Cesarean Section; Female; Fetal Blood; Fetal Hypoxia; Fetal Monitoring; He

2008
[Definition of intrapartum asphyxia and effects on outcome].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2008, Volume: 37 Suppl 1

    Topics: Acidosis; Apgar Score; Biomarkers; Brain Diseases; Cerebral Palsy; Female; Fetal Blood; Fetal Hypoxi

2008

Other Studies

10 other studies available for lactic acid and Cerebral Palsy

ArticleYear
Acute Response to One Bout of Dynamic Standing Exercise on Blood Glucose and Blood Lactate Among Children and Adolescents With Cerebral Palsy Who are Nonambulant.
    Pediatric exercise science, 2022, 05-01, Volume: 34, Issue:2

    Topics: Adolescent; Blood Glucose; Cerebral Palsy; Child; Exercise; Humans; Hyperlactatemia; Lactic Acid

2022
Bilateral muscle strength symmetry and performance are improved following walk training with restricted blood flow in an elite paralympic sprint runner: Case study.
    Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine, 2016, Volume: 20

    Topics: Adaptation, Physiological; Cerebral Palsy; Humans; Lactic Acid; Leg; Male; Muscle Strength; Muscle,

2016
Cerebral metabolism in severe neonatal hyperbilirubinemia.
    Pediatrics, 2004, Volume: 114, Issue:1

    Topics: Aspartic Acid; Basal Ganglia; Bilirubin; Cerebral Palsy; Choline; Evoked Potentials, Auditory, Brain

2004
Postoperative lactate concentrations predict the outcome of infants aged 6 weeks or less after intracardiac surgery: a cohort follow-up to 18 months.
    The Journal of thoracic and cardiovascular surgery, 2005, Volume: 130, Issue:3

    Topics: Biomarkers; Blindness; Cardiac Surgical Procedures; Cerebral Palsy; Child Development; Cohort Studie

2005
Prevention of cerebral palsy during labour: role of foetal lactate.
    Archives of gynecology and obstetrics, 2008, Volume: 278, Issue:1

    Topics: Acidosis, Lactic; Apgar Score; Asphyxia; Cerebral Palsy; Extraction, Obstetrical; Female; Fetal Bloo

2008
Proton nuclear magnetic resonance of human muscle extracts.
    Clinical physiology and biochemistry, 1984, Volume: 2, Issue:1

    Topics: Cerebral Palsy; Creatine; Glucose; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; M

1984
Longitudinal study of physical working capacity of young people with spastic cerebral palsy.
    Developmental medicine and child neurology, 1984, Volume: 26, Issue:3

    Topics: Adolescent; Cerebral Palsy; Child; Disability Evaluation; Exercise Test; Female; Heart Rate; Humans;

1984
Use of brain lactate levels to predict outcome after perinatal asphyxia.
    Acta paediatrica (Oslo, Norway : 1992), 1996, Volume: 85, Issue:7

    Topics: Asphyxia Neonatorum; Brain Chemistry; Brain Damage, Chronic; Cerebral Palsy; Cerebrovascular Circula

1996
Correlation of basal ganglia magnetic resonance spectroscopy with Apgar score in perinatal asphyxia.
    Archives of neurology, 1999, Volume: 56, Issue:12

    Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Cerebral Palsy; Choline; Humans; Inf

1999
Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia.
    Brain research, 2002, Jun-28, Volume: 942, Issue:1-2

    Topics: Animals; Animals, Newborn; Bacterial Infections; Blood Pressure; Brain; Cerebral Palsy; Encephalitis

2002