lactic acid has been researched along with Cerebellar Ataxia in 7 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maternally inherited diabetes and deafness (MIDD) and myoencephalopathy, lactic acidosis, stroke-like episodes (MELAS) syndromes are characterized by the same A3243G mutation of mitochondrial DNA (mtDNA)." | 3.75 | Brain anomalies in maternally inherited diabetes and deafness syndrome. ( Cozzone, PJ; Felician, O; Fromont, I; Lebail, B; Lefur, Y; Mancini, J; Nicoli, F; Paquis-Flucklinger, V; Valéro, R; Vialettes, B, 2009) |
| "Inherited ataxias are a group of heterogeneous disorders in children or adults but their genetic definition remains still undetermined in almost half of the patients." | 1.43 | Cerebellar ataxia and severe muscle CoQ10 deficiency in a patient with a novel mutation in ADCK3. ( Barca, E; DiMauro, S; Granata, F; Marino, S; Montagnese, F; Musumeci, O; Nunnari, D; Peverelli, L; Quinzii, CM; Toscano, A, 2016) |
| "Cerebellar ataxia is known to occasionally occur in the course of mitochondrial disorders." | 1.35 | 1H MRS spectroscopy evidence of cerebellar high lactate in mitochondrial respiratory chain deficiency. ( Bahi-Buisson, N; Boddaert, N; Brami-Zylberberg, F; Brunelle, F; de Lonlay, P; Desguerre, I; Funalot, B; Lebre, AS; Munnich, A; Rio, M; Romano, S; Rötig, A; Sarzi, E; Seidenwurm, D; Valayannopoulos, V, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Rumyantseva, A | 1 |
| Motori, E | 1 |
| Trifunovic, A | 1 |
| Márquez, G | 1 |
| Romero-Arenas, S | 1 |
| Marín-Pagán, C | 1 |
| Vera-Ibañez, A | 1 |
| FernáNdez Del Olmo, M | 1 |
| Taube, W | 1 |
| Barca, E | 1 |
| Musumeci, O | 1 |
| Montagnese, F | 1 |
| Marino, S | 1 |
| Granata, F | 1 |
| Nunnari, D | 1 |
| Peverelli, L | 1 |
| DiMauro, S | 1 |
| Quinzii, CM | 1 |
| Toscano, A | 1 |
| Fromont, I | 1 |
| Nicoli, F | 1 |
| Valéro, R | 1 |
| Felician, O | 1 |
| Lebail, B | 1 |
| Lefur, Y | 1 |
| Mancini, J | 1 |
| Paquis-Flucklinger, V | 1 |
| Cozzone, PJ | 1 |
| Vialettes, B | 1 |
| Jurkiewicz, E | 1 |
| Mierzewska, H | 1 |
| Bekiesińska-Figatowska, M | 1 |
| Pakua-Kościesza, I | 1 |
| Kmieć, T | 1 |
| Scheper, G | 1 |
| van der Knaap, MS | 1 |
| Pronicka, E | 1 |
| Boddaert, N | 1 |
| Romano, S | 1 |
| Funalot, B | 1 |
| Rio, M | 1 |
| Sarzi, E | 1 |
| Lebre, AS | 1 |
| Bahi-Buisson, N | 1 |
| Valayannopoulos, V | 1 |
| Desguerre, I | 2 |
| Seidenwurm, D | 1 |
| Brunelle, F | 1 |
| Brami-Zylberberg, F | 1 |
| Rötig, A | 1 |
| Munnich, A | 1 |
| de Lonlay, P | 1 |
| Boitier, E | 1 |
| Degoul, F | 1 |
| Charpentier, C | 1 |
| François, D | 1 |
| Ponsot, G | 1 |
| Diry, M | 1 |
| Rustin, P | 1 |
| Marsac, C | 1 |
7 other studies available for lactic acid and Cerebellar Ataxia
| Article | Year |
|---|---|
DARS2 is indispensable for Purkinje cell survival and protects against cerebellar ataxia.
Topics: Animals; Aspartate-tRNA Ligase; Brain Stem; Cell Survival; Cerebellar Ataxia; Cerebellum; Humans; La | 2020 |
Peripheral and central fatigue after high intensity resistance circuit training.
Topics: Case-Control Studies; Cerebellar Ataxia; Circuit-Based Exercise; Female; Humans; Lactic Acid; Male; | 2017 |
Cerebellar ataxia and severe muscle CoQ10 deficiency in a patient with a novel mutation in ADCK3.
Topics: Ataxia; Cerebellar Ataxia; Codon, Nonsense; Delayed Diagnosis; Electron Transport Chain Complex Prot | 2016 |
Brain anomalies in maternally inherited diabetes and deafness syndrome.
Topics: Adult; Aged; Brain; Cerebellar Ataxia; Cognition Disorders; Deafness; Diabetes Mellitus; Diabetes Me | 2009 |
MRI of a family with leukoencephalypathy with vanishing white matter.
Topics: Adolescent; Amino Acid Substitution; Aspartic Acid; Brain; Case-Control Studies; Cerebellar Ataxia; | 2005 |
1H MRS spectroscopy evidence of cerebellar high lactate in mitochondrial respiratory chain deficiency.
Topics: Adolescent; Cerebellar Ataxia; Cerebellum; Child; Child, Preschool; Humans; Infant; Infant, Newborn; | 2008 |
A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency.
Topics: Cerebellar Ataxia; Child, Preschool; Coenzymes; Electron Transport; Epilepsy; Humans; Kinetics; Lact | 1998 |