lactic acid has been researched along with Central Nervous System Diseases in 21 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The disorders causing myoclonus have been compared to those in which myoclonus has been reported." | 2.37 | Myoclonus and mitochondrial myopathy. ( Hopkins, LC; Rosing, HS, 1986) |
| "Ropinirole hydrochloride (RPN), a nonergot dopamine D2-agonist used in the management of Parkinson's disease, has poor oral bioavailability (52%) due to extensive hepatic metabolism." | 1.39 | Fabrication and statistical optimization of surface engineered PLGA nanoparticles for naso-brain delivery of ropinirole hydrochloride: in-vitro-ex-vivo studies. ( Patil, GB; Surana, SJ, 2013) |
| "In multiple sclerosis, myelopathy, stroke, epilepsy and viral meningitis glutamate, hypoxanthine, xanthine, and uric acid are increased 2-3-fold compared to controls." | 1.30 | Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. ( Kempski, OS; Lowitzsch, K; Stover, JF, 1997) |
| "Lactic acid concentration has been determined in the cerebrospinal fluid (CSF) of 715 patients suffering from various neurological diseases." | 1.27 | [Importance of cerebrospinal fluid lactate determination in neurological diseases]. ( Busse, O; Hornig, CR; Kaps, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Fitz, FR | 1 |
| Reese, M | 1 |
| Patil, GB | 1 |
| Surana, SJ | 1 |
| Kelbich, P | 1 |
| Hejčl, A | 1 |
| Krulichová, IS | 1 |
| Procházka, J | 1 |
| Hanuljaková, E | 1 |
| Peruthová, J | 1 |
| Koudelková, M | 1 |
| Sameš, M | 1 |
| Krejsek, J | 1 |
| Tahara, K | 1 |
| Miyazaki, Y | 1 |
| Kawashima, Y | 1 |
| Kreuter, J | 1 |
| Yamamoto, H | 1 |
| Yamada, K | 1 |
| Toribe, Y | 1 |
| Yanagihara, K | 1 |
| Mano, T | 1 |
| Akagi, M | 1 |
| Suzuki, Y | 1 |
| Lejon, V | 1 |
| Reiber, H | 1 |
| Legros, D | 1 |
| Djé, N | 1 |
| Magnus, E | 1 |
| Wouters, I | 1 |
| Sindic, CJ | 1 |
| Büscher, P | 1 |
| Gujar, SK | 1 |
| Maheshwari, S | 1 |
| Björkman-Burtscher, I | 1 |
| Sundgren, PC | 1 |
| Fukunaga, FH | 1 |
| Tsuchiyama, A | 1 |
| Oyanagi, K | 1 |
| Sogawa, H | 1 |
| Nakao, T | 1 |
| Ogawa, K | 1 |
| Fujita, S | 1 |
| Hornig, CR | 1 |
| Busse, O | 1 |
| Kaps, M | 1 |
| Leu, HS | 1 |
| Huang, CH | 1 |
| Cheng, DL | 1 |
| Hiraoka, A | 1 |
| Miura, I | 1 |
| Hattori, M | 1 |
| Tominaga, I | 1 |
| Kushida, K | 1 |
| Maeda, M | 1 |
| Stover, JF | 1 |
| Lowitzsch, K | 1 |
| Kempski, OS | 1 |
| Cao, X | 1 |
| Schoichet, MS | 1 |
| Godey, F | 1 |
| Bouasria, A | 1 |
| Ropert, M | 1 |
| Diakite, M | 1 |
| Le Treut, A | 1 |
| Balençon, M | 1 |
| Vanuxem, P | 1 |
| Vanuxem, D | 1 |
| Raharison, L | 1 |
| Aubert, M | 1 |
| Pouliquen, G | 1 |
| Deslangles, O | 1 |
| Agapejev, S | 1 |
| Vassilieff, I | 1 |
| Curi, PR | 1 |
| Krendel, DA | 1 |
| Pilch, JF | 1 |
| Stahl, RL | 1 |
| Stöffler, A | 1 |
| Baas, H | 1 |
| Fischer, PA | 1 |
| Hopkins, LC | 1 |
| Rosing, HS | 1 |
| Petty, RK | 1 |
| Harding, AE | 1 |
| Morgan-Hughes, JA | 1 |
3 reviews available for lactic acid and Central Nervous System Diseases
| Article | Year |
|---|---|
Magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Central Nervous System Diseases; Choline; Creatine; Humans; Lactic Acid; Magne | 2005 |
Cerebrospinal fluid--a re-examination.
Topics: Adult; Antigens, Bacterial; Central Nervous System Diseases; Cerebrospinal Fluid; Cerebrospinal Flui | 1984 |
Myoclonus and mitochondrial myopathy.
Topics: Adolescent; Brain Diseases, Metabolic; Central Nervous System Diseases; Electroencephalography; Epil | 1986 |
1 trial available for lactic acid and Central Nervous System Diseases
| Article | Year |
|---|---|
Maximal exercise and muscle energy metabolism after recovery from exercise hyperthermia syndrome.
Topics: Adult; Blood Pressure; Body Temperature; Central Nervous System Diseases; Convalescence; Creatine Ki | 2001 |
17 other studies available for lactic acid and Central Nervous System Diseases
| Article | Year |
|---|---|
Association between cerebrospinal fluid lactate concentration and central nervous system disease in dogs.
Topics: Animals; Central Nervous System Diseases; Dog Diseases; Dogs; Lactic Acid | 2020 |
Fabrication and statistical optimization of surface engineered PLGA nanoparticles for naso-brain delivery of ropinirole hydrochloride: in-vitro-ex-vivo studies.
Topics: Animals; Brain; Calorimetry, Differential Scanning; Central Nervous System Diseases; Dopamine Agonis | 2013 |
Coefficient of energy balance, a new parameter for basic investigation of the cerebrospinal fluid.
Topics: Adenosine Triphosphate; Central Nervous System Diseases; Cerebrospinal Fluid; Energy Metabolism; Glu | 2014 |
Brain targeting with surface-modified poly(D,L-lactic-co-glycolic acid) nanoparticles delivered via carotid artery administration.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Carotid Arteries; Central Nervous System Disea | 2011 |
Diagnostic accuracy of blood and CSF lactate in identifying children with mitochondrial diseases affecting the central nervous system.
Topics: Adolescent; Area Under Curve; Central Nervous System Diseases; Child; Child, Preschool; Female; Huma | 2012 |
Intrathecal immune response pattern for improved diagnosis of central nervous system involvement in trypanosomiasis.
Topics: Adult; Animals; Antibodies, Protozoan; Blood-Brain Barrier; Central Nervous System Diseases; Cerebro | 2003 |
Normal activities of hepatic pyruvate dehydrogenase and pyruvate carboxylase in Leigh's syndrome.
Topics: Brain; Brain Stem; Central Nervous System Diseases; Encephalomalacia; Humans; Infant; Intellectual D | 1983 |
[Importance of cerebrospinal fluid lactate determination in neurological diseases].
Topics: Central Nervous System Diseases; Cerebrovascular Disorders; Diagnosis, Differential; Encephalitis; E | 1983 |
[The diagnostic value of cerebrospinal fluid lactic acid level in central nervous system infection (author's transl)].
Topics: Adolescent; Adult; Aged; Central Nervous System Diseases; Diagnosis, Differential; Evaluation Studie | 1981 |
Proton magnetic resonance spectroscopy of cerebrospinal fluid as an aid in neurological diagnosis.
Topics: Adult; Aged; Central Nervous System Diseases; Cerebral Infarction; Cerebrospinal Fluid; Female; Gluc | 1994 |
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pr | 1997 |
Delivering neuroactive molecules from biodegradable microspheres for application in central nervous system disorders.
Topics: Animals; Biodegradation, Environmental; Cell Differentiation; Central Nervous System Diseases; Drug | 1999 |
Don't forget to test for D-lactic acid in short bowel syndrome.
Topics: Acidosis, Lactic; Central Nervous System Diseases; Child, Preschool; Female; Humans; Lactic Acid; Sh | 2000 |
Alcohol levels in cerebrospinal fluid and blood samples from patients under pathological conditions.
Topics: Adolescent; Adult; Aged; Blood Glucose; Blood-Brain Barrier; Central Nervous System Diseases; Child; | 1992 |
Central hyperventilation in primary CNS lymphoma: evidence implicating CSF lactic acid.
Topics: Central Nervous System Diseases; Female; Humans; Hyperventilation; Lactates; Lactic Acid; Lymphoma; | 1991 |
[Polymorphonuclear leukocyte elastase in the cerebrospinal fluid in the diagnosis of acute inflammatory central nervous system diseases].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Central Nervous System Diseases; C | 1989 |
The clinical features of mitochondrial myopathy.
Topics: Adolescent; Adult; Aged; Central Nervous System Diseases; Creatine Kinase; Eye Diseases; Female; Hum | 1986 |