lactic acid has been researched along with Central Hypothyroidism in 15 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| " The aim of this study was to investigate the effects of hypothyroidism on leucine, mannose, glucose and lactate metabolism in rat cerebellar slices." | 7.79 | Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices. ( da Silveira, CK; de Assis, AM; Farina, M; Longoni, A; Müller, AP; Perry, ML; Souza, DO, 2013) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| " The aim of this study was to investigate the effects of hypothyroidism on leucine, mannose, glucose and lactate metabolism in rat cerebellar slices." | 3.79 | Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices. ( da Silveira, CK; de Assis, AM; Farina, M; Longoni, A; Müller, AP; Perry, ML; Souza, DO, 2013) |
| "Further, neonatal hypothyroidism affected germ cell proliferation with decreased expression of proliferating cell nuclear antigen (PCNA) and Cx43." | 1.46 | Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43. ( Sarkar, D; Singh, SK, 2017) |
| "Treatment with triiodothyronine for 5 or 10 days decreased the sensitivity of glycogen synthesis but increased the sensitivity of lactate formation to insulin." | 1.30 | The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats. ( Bevan, S; Challiss, RA; Dimitriadis, G; Krause, U; Leighton, B; Newsholme, EA; Parry-Billings, M; Piva, T; Tegos, K; Wegener, G, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hiraki, N | 1 |
| Tanaka, TD | 1 |
| Yoshimura, M | 1 |
| Goonoo, MS | 1 |
| Morris, R | 1 |
| Raithatha, A | 1 |
| Creagh, F | 1 |
| Sarkar, D | 1 |
| Singh, SK | 1 |
| Müller, AP | 1 |
| Longoni, A | 1 |
| Farina, M | 1 |
| da Silveira, CK | 1 |
| Souza, DO | 1 |
| Perry, ML | 1 |
| de Assis, AM | 1 |
| Lankhaar, JA | 1 |
| de Vries, WR | 1 |
| Jansen, JA | 1 |
| Zelissen, PM | 1 |
| Backx, FJ | 1 |
| Eynan, M | 1 |
| Knubuvetz, T | 1 |
| Meiri, U | 1 |
| Navon, G | 1 |
| Gerstenblith, G | 1 |
| Bromberg, Z | 1 |
| Hasin, Y | 1 |
| Horowitz, M | 1 |
| Caraccio, N | 1 |
| Natali, A | 1 |
| Sironi, A | 1 |
| Baldi, S | 1 |
| Frascerra, S | 1 |
| Dardano, A | 1 |
| Monzani, F | 1 |
| Ferrannini, E | 1 |
| Storm, H | 1 |
| Van Hardeveld, C | 1 |
| Kassenaar, AA | 1 |
| Almeida, A | 1 |
| González-Buitrago, JM | 1 |
| Bolaños, JP | 1 |
| Medina, JM | 1 |
| Dimitriadis, G | 1 |
| Parry-Billings, M | 1 |
| Bevan, S | 1 |
| Leighton, B | 1 |
| Krause, U | 1 |
| Piva, T | 1 |
| Tegos, K | 1 |
| Challiss, RA | 1 |
| Wegener, G | 1 |
| Newsholme, EA | 1 |
| Kneer, N | 1 |
| Lardy, H | 1 |
| Müller, MJ | 1 |
| Seitz, HJ | 1 |
| Dudley, GA | 1 |
| Tullson, PC | 1 |
| Terjung, RL | 1 |
| Everts, ME | 1 |
| Clausen, T | 1 |
| Heimberg, M | 1 |
| Olubadewo, JO | 1 |
| Wilcox, HG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Central Hypothyroidism
| Article | Year |
|---|---|
Impact of overt and subclinical hypothyroidism on exercise tolerance: a systematic review.
Topics: Blood Flow Velocity; Blood Pressure; Echocardiography; Electrocardiography; Exercise Tolerance; Hear | 2014 |
Plasma lipoproteins and regulation of hepatic metabolism of fatty acids in altered thyroid states.
Topics: Alanine; Animals; Apolipoproteins; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids; Fatty Acids, Non | 1985 |
1 trial available for lactic acid and Central Hypothyroidism
| Article | Year |
|---|---|
Muscle metabolism and exercise tolerance in subclinical hypothyroidism: a controlled trial of levothyroxine.
Topics: Adult; Double-Blind Method; Exercise; Fatty Acids, Nonesterified; Female; Follow-Up Studies; Hormone | 2005 |
12 other studies available for lactic acid and Central Hypothyroidism
| Article | Year |
|---|---|
A Man With Left Ventricular Hypertrophy.
Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc | 2022 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43.
Topics: Age Factors; Animals; Animals, Newborn; Antioxidants; Apoptosis; Cell Proliferation; Connexin 43; Di | 2017 |
Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices.
Topics: Animals; Carbon Dioxide; Cerebellum; Disease Models, Animal; Female; Glucose; Hypothyroidism; Lactat | 2013 |
Heat acclimation-induced elevated glycogen, glycolysis, and low thyroxine improve heart ischemic tolerance.
Topics: Acclimatization; Animals; Carbon Isotopes; Glucose; Glycogen; Glycolysis; Hot Temperature; Hypothyro | 2002 |
The influence of hypothyroidism on the adrenergic stimulation of glycogenolysis in perfused rat liver.
Topics: Animals; Calcium; Glucose-6-Phosphate; Glucosephosphates; Hypothyroidism; Lactates; Lactic Acid; Liv | 1984 |
Fuel utilization by early newborn brain is preserved under congenital hypothyroidism in the rat.
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Antithyroid Agents; Brain; Congenital Hypothyroidi | 1996 |
The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats.
Topics: Animals; Biological Transport, Active; Cortisone; Dinoprostone; Drug Interactions; Glucose; Glycogen | 1997 |
Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cyclic AMP; Dehydroepiandrosterone; Glucagon; Gluconeogenesis | 2000 |
Interrelation between thyroid state and the effect of glucagon on gluconeogenesis in perfused rat livers.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Aminoisobutyric Acids; An | 1987 |
Influence of mitochondrial content on the sensitivity of respiratory control.
Topics: Adenylate Kinase; AMP Deaminase; Animals; Creatine Kinase; Glycolysis; Hypothyroidism; Lactates; Lac | 1987 |
Effects of thyroid hormones on calcium contents and 45Ca exchange in rat skeletal muscle.
Topics: Animals; Calcium; Calcium Radioisotopes; Dantrolene; Female; Gallopamil; Hyperthyroidism; Hypothyroi | 1986 |