lactic acid has been researched along with Cells, Neoplasm Circulating in 8 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, many metastases display different metabolic traits compared with the tumours from which they originate, enabling survival and growth in the new environment." | 2.72 | The metabolism of cancer cells during metastasis. ( Bergers, G; Fendt, SM, 2021) |
| "Osteosarcoma is the most common primary malignant bone tumor in adolescents and children and prone to develop lung metastasis." | 1.91 | Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis. ( Gao, Y; Liu, Y; Sheng, G; Wu, H; Yang, Y, 2023) |
| "Lung cancer is the major cause of cancer related lethality worldwide, and metastasis to distant organs is the pivotal cause of death for the vast majority of lung cancer patients." | 1.42 | Active targeting docetaxel-PLA nanoparticles eradicate circulating lung cancer stem-like cells and inhibit liver metastasis. ( Hou, C; Jiang, Y; Liu, Y; Sun, B; Yang, N; Zhang, H; Zheng, J; Zuo, P, 2015) |
| "Based on the metabolic features of cancer cells, live CTCs can be quantified indirectly through their lactic acid production." | 1.42 | Development of a microfluidic-based optical sensing device for label-free detection of circulating tumor cells (CTCs) through their lactic acid metabolism. ( Chiu, TK; Hsiao, HB; Hsieh, CH; Lei, KF; Wang, HM; Wu, MH, 2015) |
| "The detection of a small number of circulating tumor cells (CTCs) is important, especially in the early stages of cancer." | 1.38 | Nanotextured substrates with immobilized aptamers for cancer cell isolation and cytology. ( Allen, PB; Bachoo, R; Ellington, AD; Iqbal, SM; Kim, YT; Li, N; Mahmood, MA; Wan, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, G | 1 |
| Gao, Y | 1 |
| Wu, H | 1 |
| Liu, Y | 2 |
| Yang, Y | 1 |
| Bergers, G | 1 |
| Fendt, SM | 1 |
| Jiang, W | 1 |
| Wang, H | 1 |
| Cui, Y | 1 |
| Lei, Y | 1 |
| Wang, Y | 1 |
| Xu, D | 1 |
| Jiang, N | 1 |
| Chen, Y | 1 |
| Sun, Y | 1 |
| Zhang, Y | 1 |
| Cao, J | 1 |
| Ke, Z | 1 |
| Hou, S | 2 |
| Zhao, L | 2 |
| Shen, Q | 2 |
| Yu, J | 2 |
| Ng, C | 1 |
| Kong, X | 1 |
| Wu, D | 2 |
| Song, M | 2 |
| Shi, X | 1 |
| Xu, X | 2 |
| OuYang, WH | 2 |
| He, R | 1 |
| Zhao, XZ | 1 |
| Lee, T | 2 |
| Brunicardi, FC | 1 |
| Garcia, MA | 2 |
| Ribas, A | 1 |
| Lo, RS | 1 |
| Tseng, HR | 2 |
| Lu, YT | 1 |
| Li, F | 1 |
| Wu, K | 1 |
| Luo, Z | 1 |
| Fang, X | 1 |
| Shao, C | 1 |
| Chung, LW | 1 |
| Rettig, M | 1 |
| Posadas, EM | 1 |
| Yang, N | 1 |
| Jiang, Y | 1 |
| Zhang, H | 1 |
| Sun, B | 1 |
| Hou, C | 1 |
| Zheng, J | 1 |
| Zuo, P | 1 |
| Chiu, TK | 1 |
| Lei, KF | 1 |
| Hsieh, CH | 1 |
| Hsiao, HB | 1 |
| Wang, HM | 1 |
| Wu, MH | 1 |
| Wan, Y | 1 |
| Mahmood, MA | 1 |
| Li, N | 1 |
| Allen, PB | 1 |
| Kim, YT | 1 |
| Bachoo, R | 1 |
| Ellington, AD | 1 |
| Iqbal, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Safety and Efficacy of Esperanza Extract (Petiveria Alliacea) in Patients With Metastatic Gastrointestinal Tumors and Acute Leukemia[NCT05587088] | Phase 1/Phase 2 | 82 participants (Anticipated) | Interventional | 2022-12-15 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Cells, Neoplasm Circulating
| Article | Year |
|---|---|
The metabolism of cancer cells during metastasis.
Topics: Acetates; Adenosine Triphosphate; Animals; Cell Plasticity; Fatty Acids; Glutamine; Humans; Lactic A | 2021 |
7 other studies available for lactic acid and Cells, Neoplasm Circulating
| Article | Year |
|---|---|
Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis.
Topics: Bone Neoplasms; Glucose; Humans; Lactic Acid; Monocarboxylic Acid Transporters; Neoplastic Cells, Ci | 2023 |
Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Count; C | 2018 |
Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells.
Topics: Cell Line, Tumor; Cell Separation; Erythrocytes; Humans; Lactic Acid; Melanoma; Microfluidic Analyti | 2013 |
High-purity prostate circulating tumor cell isolation by a polymer nanofiber-embedded microchip for whole exome sequencing.
Topics: Cell Line, Tumor; Cell Separation; Exome; Genomics; Humans; Lactic Acid; Male; Microchip Analytical | 2013 |
Active targeting docetaxel-PLA nanoparticles eradicate circulating lung cancer stem-like cells and inhibit liver metastasis.
Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Docetaxe | 2015 |
Development of a microfluidic-based optical sensing device for label-free detection of circulating tumor cells (CTCs) through their lactic acid metabolism.
Topics: Biosensing Techniques; Cell Line, Tumor; Cell Separation; Cell Survival; Humans; Lactic Acid; Leukoc | 2015 |
Nanotextured substrates with immobilized aptamers for cancer cell isolation and cytology.
Topics: Aptamers, Nucleotide; Brain Neoplasms; Cell Separation; Cells, Cultured; Cytodiagnosis; Cytological | 2012 |