lactic acid has been researched along with Cardiotoxicity in 5 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When compared to cocaine exposure alone, CE exposure in ED patients with acute drug overdose was significantly associated with higher occurrence of cardiac arrest, higher mean lactate concentrations, and lower occurrence of myocardial injury." | 8.31 | Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose. ( Manini, AF; Manoochehri, O; Richardson, LD; Shastry, S, 2023) |
| "When compared to cocaine exposure alone, CE exposure in ED patients with acute drug overdose was significantly associated with higher occurrence of cardiac arrest, higher mean lactate concentrations, and lower occurrence of myocardial injury." | 4.31 | Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose. ( Manini, AF; Manoochehri, O; Richardson, LD; Shastry, S, 2023) |
| "Mitoxantrone (MTX) is an antineoplastic agent used to treat several types of cancers and on multiple sclerosis, which shows a high incidence of cardiotoxicity." | 3.85 | Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy. ( Bastos, ML; Carvalho, F; Carvalho, RA; Costa, VM; Gomes, AS; Pinto, M; Reis-Mendes, A; Remião, F; Sousa, E, 2017) |
| "Pre-treatment with the extracts and metformin elicited a cardioprotective effect, as indicated by the prevention of doxorubicin-induced cardiac oxidative stress and prevention of adverse alterations in plasma cardiac markers, cardiac lipids and electrolyte profiles, as well as improvement of the activities of cardiac ATPases, creatine kinase and lactate dehydrogenase." | 1.62 | Attenuation of doxorubicin-induced cardiotoxicity in Wistar rats by aqueous leaf-extracts of Chromolaena odorata and Tridax procumbens. ( Adeku, KA; Ifeanacho, MO; Ikewuchi, CC; Ikewuchi, JC; Jaja, VS; Jamabo, CN; Okezue, EC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shastry, S | 1 |
| Manoochehri, O | 1 |
| Richardson, LD | 1 |
| Manini, AF | 1 |
| Park, JM | 1 |
| Reed, GD | 1 |
| Liticker, J | 1 |
| Putnam, WC | 1 |
| Chandra, A | 1 |
| Yaros, K | 1 |
| Afzal, A | 1 |
| MacNamara, J | 1 |
| Raza, J | 1 |
| Hall, RG | 1 |
| Baxter, J | 1 |
| Derner, K | 1 |
| Pena, S | 1 |
| Kallem, RR | 1 |
| Subramaniyan, I | 1 |
| Edpuganti, V | 1 |
| Harrison, CE | 1 |
| Muthukumar, A | 1 |
| Lewis, C | 1 |
| Reddy, S | 1 |
| Unni, N | 1 |
| Klemow, D | 1 |
| Syed, S | 1 |
| Li, H | 1 |
| Cole, S | 1 |
| Froehlich, T | 1 |
| Ayers, C | 1 |
| de Lemos, J | 1 |
| Malloy, CR | 1 |
| Haley, B | 1 |
| Zaha, VG | 1 |
| Ikewuchi, JC | 1 |
| Ikewuchi, CC | 1 |
| Ifeanacho, MO | 1 |
| Jaja, VS | 1 |
| Okezue, EC | 1 |
| Jamabo, CN | 1 |
| Adeku, KA | 1 |
| Nasr, M | 1 |
| Nafee, N | 1 |
| Saad, H | 1 |
| Kazem, A | 1 |
| Reis-Mendes, A | 1 |
| Gomes, AS | 1 |
| Carvalho, RA | 1 |
| Carvalho, F | 1 |
| Remião, F | 1 |
| Pinto, M | 1 |
| Bastos, ML | 1 |
| Sousa, E | 1 |
| Costa, VM | 1 |
5 other studies available for lactic acid and Cardiotoxicity
| Article | Year |
|---|---|
Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose.
Topics: Adult; Cardiotoxicity; Cocaine; Drug Overdose; Emergency Service, Hospital; Ethanol; Heart Arrest; H | 2023 |
Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.
Topics: Adult; Antibiotics, Antineoplastic; Bicarbonates; Breast Neoplasms; Carbon-13 Magnetic Resonance Spe | 2020 |
Attenuation of doxorubicin-induced cardiotoxicity in Wistar rats by aqueous leaf-extracts of Chromolaena odorata and Tridax procumbens.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Cholesterol; C | 2021 |
Improved antitumor activity and reduced cardiotoxicity of epirubicin using hepatocyte-targeted nanoparticles combined with tocotrienols against hepatocellular carcinoma in mice.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; C | 2014 |
Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy.
Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Autophagy; Cardiotoxicity; Cell Lin | 2017 |