Page last updated: 2024-10-17

lactic acid and Cardiomegaly

lactic acid has been researched along with Cardiomegaly in 42 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Pimobendan has gained enormous importance in the treatment of mitral valve disease in dogs."6.90Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly. ( Bach, JP; Iwanuk, N; Nolte, I; Pilgram, A; Raue, J; Rohn, K; Rumstedt, K; Sehn, M; Wall, L, 2019)
"Pimobendan has gained enormous importance in the treatment of mitral valve disease in dogs."2.90Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly. ( Bach, JP; Iwanuk, N; Nolte, I; Pilgram, A; Raue, J; Rohn, K; Rumstedt, K; Sehn, M; Wall, L, 2019)
"As evidence on the predominant type of cardiac hypertrophy due to endurance running training is inconsistent, the aim of this study was to investigate the effect of increased training volume on echocardiographic variables of distance runners."2.72Concentric myocardial hypertrophy after one year of increased training volume in experienced distance runners. ( Raugaliene, R; Stasiulis, A; Venckunas, T, 2006)
"Mice were subjected to cardiac hypertrophy secondary to pressure-overload as a result of an abdominal aortic constriction (AAC)."1.39Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy. ( Jaswal, JS; Lopaschuk, GD; Sankaralingam, S; Ussher, JR; Wagg, C; Zaugg, M; Zhang, L, 2013)
"Exercise-induced cardiac hypertrophy has been recently identified to be regulated in a sex-specific manner."1.37Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability. ( Benz, V; Böhm, C; Dragun, D; Foryst-Ludwig, A; Gürgen, D; Kintscher, U; Kreissl, MC; Mai, K; Regitz-Zagrosek, V; Schubert, C; Sprang, C; Spranger, J; Stawowy, P; Thalke, B; Unger, T, 2011)
"Heart hypertrophy is a common finding of acromegaly, a syndrome due to GH excess."1.34Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH. ( Bartalena, L; Bogazzi, F; D'Alessio, A; Fanelli, G; Gasperi, M; Manariti, A; Martino, E; Raggi, F; Russo, D; Ultimieri, F; Viacava, P, 2007)
"Hypertension-induced pathological cardiac hypertrophy (hypertensive heart) and exercise training-induced physiological cardiac hypertrophy (athletic heart) have differences in cardiac properties."1.32Cardiac hypertrophy by hypertension and exercise training exhibits different gene expression of enzymes in energy metabolism. ( Fujii, N; Iemitsu, M; Kakinuma, Y; Maeda, S; Matsuda, M; Miyauchi, T; Miyazaki, H; Sakai, S; Yamaguchi, I, 2003)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19909 (21.43)18.7374
1990's15 (35.71)18.2507
2000's11 (26.19)29.6817
2010's5 (11.90)24.3611
2020's2 (4.76)2.80

Authors

AuthorsStudies
Jian, L1
Gao, X1
Wang, C1
Sun, X1
Xu, Y1
Han, R1
Wang, Y1
Xu, S1
Ding, L1
Zhou, J1
Gu, Y1
Zhao, Y1
Yang, Y1
Yuan, Y1
Ye, J1
Zhang, L2
Iwanuk, N1
Wall, L1
Nolte, I1
Raue, J1
Rumstedt, K1
Pilgram, A1
Sehn, M1
Rohn, K1
Bach, JP1
Cluntun, AA1
Badolia, R1
Lettlova, S1
Parnell, KM1
Shankar, TS1
Diakos, NA1
Olson, KA1
Taleb, I1
Tatum, SM1
Berg, JA1
Cunningham, CN1
Van Ry, T1
Bott, AJ1
Krokidi, AT1
Fogarty, S1
Skedros, S1
Swiatek, WI1
Yu, X1
Luo, B1
Merx, S1
Navankasattusas, S1
Cox, JE1
Ducker, GS1
Holland, WL1
McKellar, SH1
Rutter, J1
Drakos, SG1
Jaswal, JS1
Ussher, JR1
Sankaralingam, S1
Wagg, C1
Zaugg, M1
Lopaschuk, GD3
Avad, AS1
Lutsenko, RV1
Malyk, SV1
Foryst-Ludwig, A1
Kreissl, MC1
Sprang, C1
Thalke, B1
Böhm, C1
Benz, V1
Gürgen, D1
Dragun, D1
Schubert, C1
Mai, K1
Stawowy, P1
Spranger, J1
Regitz-Zagrosek, V1
Unger, T1
Kintscher, U1
Prada, CE1
Al Jasmi, F1
Kirk, EP1
Hopp, M1
Jones, O1
Leslie, ND1
Burrow, TA1
Iemitsu, M1
Miyauchi, T1
Maeda, S1
Sakai, S1
Fujii, N1
Miyazaki, H1
Kakinuma, Y1
Matsuda, M1
Yamaguchi, I1
King, N2
Lin, H2
McGivan, JD2
Suleiman, MS2
Godfried, MH1
Boer, K1
Beuger, S1
Scherpbier, HJ1
Kuijpers, TW1
Saeedi, R1
Grist, M1
Wambolt, RB1
Bescond-Jacquet, A1
Lucien, A1
Allard, MF4
Venckunas, T1
Stasiulis, A1
Raugaliene, R1
Bogazzi, F1
Raggi, F1
Ultimieri, F1
Russo, D1
Manariti, A1
D'Alessio, A1
Viacava, P1
Fanelli, G1
Gasperi, M1
Bartalena, L1
Martino, E1
Itoh, K1
Minakawa, M1
Ono, Y1
Tsushima, T1
Fukui, K1
Fukuda, I1
Sugden, PH1
Smith, DM1
Salerno, TA1
Chiong, MA1
Bache, RJ1
Arentzen, CE1
Simon, AB1
Vrobel, TR1
McAinsh, AM1
Turner, MA1
O'Hare, D1
Nithythyananthan, R1
Johnston, DG1
O'Gorman, DJ1
Sheridan, DJ1
Takeuchi, K1
Buenaventura, P1
Cao-Danh, H1
Glynn, P1
Simplaceanu, E1
McGowan, FX1
del Nido, PJ2
Golden, AL1
Bright, JM1
Pohost, GM1
Pike, MM1
Mäntymaa, P1
Arokoski, J1
Pörsti, I1
Perhonen, M1
Arvola, P1
Helminen, HJ1
Takala, TE2
Leppäluoto, J2
Ruskoaho, H2
Schönekess, BO2
Henning, SL1
English, DR1
Mochizuki, T1
Eberli, FR1
Ngoy, S1
Apstein, CS3
Lorell, BH2
Rubio-Gozalbo, ME1
Smeitink, JA1
Ruitenbeek, W1
Ter Laak, H1
Mullaart, RA1
Schuelke, M1
Mariman, EC1
Sengers, RC1
Gabreëls, FJ1
Binas, B1
Danneberg, H1
McWhir, J1
Mullins, L1
Clark, AJ1
Rupert, BE1
Segar, JL1
Schutte, BC1
Scholz, TD1
Giordano, G1
Corradi, D1
D'Adda, T1
Melissari, M1
Devi, SA1
Jolitha, AB1
Prathima, S1
Goodman, JM1
McLaughlin, PR1
Plyley, MJ1
Holloway, RM1
Fell, D1
Logan, AG1
Liu, PP1
Munfakh, NA1
Steinberg, JB1
Titus, JS1
Denenberg, AG1
O'Keefe, DD1
Daggett, WM1
Geffin, GA1
Tanaka, H1
Obata, H1
Haneda, T1
Cunningham, MJ1
Weinberg, EO2
Vogel, WM1
Gaasch, WH1
Zile, MR1
Hoshino, PK1
Rhodes, DR1
Anderson, PG1
Thomas, GD1
Bishop, SP1
Digerness, SB1
Scheld, HH1
Görlach, G1
Mulch, J1
Podzuweit, T1
Höge, R1
Hehrlein, FW1
Schaper, W1
Kinnunen, P1
Taskinen, T1
Vuolteenaho, O1
Ji, LL1
Stratman, FW1
Lardy, HA1
Whitmer, JT1
Benson, LN1
Mickle, DA1
Kielmanowicz, S1
Coles, JG1
Wilson, GJ1
Hickson, RC1
Foster, C1
Pollock, ML1
Galassi, TM1
Rich, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Nebivolol on Microvascular Perfusion in the Skeletal Muscles During Exercise in Hypertensive Patients[NCT01501929]Phase 432 participants (Actual)Interventional2010-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Endothelial Cell Protein Expression p47phox From Endothelial Cell Collection

Endothelial cell (EC) was collected after a 20-guage angiocatheter was inserted into the contralateral forearm vein under sterile conditions. Three J-shaped vascular guidewires (St. Jude, St. Paul, MN) were advanced sequentially into the vein up to 10 cm. Endothelial cells were collected by gentle abrasion and placed into a dissociation buffer (0.5% bovine serum albumin, 2mM EDTA, and 100 ug/ml heparin in PBS). Endothelial cells were recovered from the tips of guide wires by repeated washing into collection tubes and subsequent centrifugation. EC were incubated with monoclonal antibodies against the polyclonal antibodies against NADPH oxidase p47 subunit. The intensity of staining was measured using fluorescence microscopy. (NCT01501929)
Timeframe: 12 weeks

InterventionRatio human to HUVEC p47Phox expression (Mean)
Metoprolol0.47
Nebivolol0.44

Microvascular Blood Flow

Microvascular perfusion of skeletal muscle were measured during handgrip at 20 cycle per minute after 12 weeks of metoprolol, and after 12 weeks of nebivolol (NCT01501929)
Timeframe: 12 weeks

Interventionvideo intensity units/ second (Median)
Metoprolol43.938
Nebivolol74.584

Trials

3 trials available for lactic acid and Cardiomegaly

ArticleYear
Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly.
    PloS one, 2019, Volume: 14, Issue:10

    Topics: Animals; Cardiomegaly; Dog Diseases; Dogs; Echocardiography; Exercise Test; Female; Heart Murmurs; H

2019
[FACTORIAL ANALYSIS IN PROGNOSTICATION OF INFECTIOUS COMPLICATIONS AFTER SIMULTANT OPERATIVE INTERVENTIONS FOR BILIARY CALCULOUS DISEASE].
    Klinichna khirurhiia, 2016, Issue:3

    Topics: Aged; Algorithms; Bacterial Infections; Blood Glucose; Cardiomegaly; Cholecystectomy, Laparoscopic;

2016
Concentric myocardial hypertrophy after one year of increased training volume in experienced distance runners.
    British journal of sports medicine, 2006, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Cardiomegaly; Exercise Test; Humans; Hypertrophy, Left Ventricular; Lactic Acid;

2006

Other Studies

39 other studies available for lactic acid and Cardiomegaly

ArticleYear
Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice.
    Biology direct, 2023, 09-04, Volume: 18, Issue:1

    Topics: Animals; Cardiomegaly; Fatty Acids; Glucose; Insulin Resistance; Lactic Acid; Leptin; Mice; Perilipi

2023
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
    Cell metabolism, 2021, 03-02, Volume: 33, Issue:3

    Topics: Animals; Anion Transport Proteins; Cardiomegaly; Heart Failure; Heart-Assist Devices; Humans; Lactic

2021
Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy.
    Circulation. Heart failure, 2013, Sep-01, Volume: 6, Issue:5

    Topics: Adenosine Triphosphate; Animals; Aorta, Abdominal; Arterial Pressure; Blood Glucose; Cardiomegaly; D

2013
Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:1

    Topics: Adipose Tissue; Animals; Blotting, Western; Calorimetry; Cardiomegaly; Echocardiography; Energy Meta

2011
Cardiac disease in methylmalonic acidemia.
    The Journal of pediatrics, 2011, Volume: 159, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Aortic Valve Stenosis; Cardiomegaly; Cardiomyopathy, Dilated;

2011
Cardiac hypertrophy by hypertension and exercise training exhibits different gene expression of enzymes in energy metabolism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:10

    Topics: Animals; Cardiomegaly; Carnitine O-Palmitoyltransferase; CD36 Antigens; Coenzyme A Ligases; Fatty Ac

2003
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting,

2004
A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother.
    European journal of pediatrics, 2005, Volume: 164, Issue:3

    Topics: Adipose Tissue; Antiretroviral Therapy, Highly Active; Arginine; Asphyxia; Brain; Cardiomegaly; Card

2005
Trimetazidine normalizes postischemic function of hypertrophied rat hearts.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Glucose; Glycolysis; Kinetics;

2005
Expression and activity of the glutamate transporter EAAT2 in cardiac hypertrophy: implications for ischaemia reperfusion injury.
    Pflugers Archiv : European journal of physiology, 2006, Volume: 452, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cardiac Output; Cardiomegaly; Cardiotonic Agents; Excitatory Amino

2006
Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.
    The Journal of endocrinology, 2007, Volume: 194, Issue:3

    Topics: Acromegaly; Adenine Nucleotide Translocator 1; Adenosine Triphosphate; Animals; Blotting, Western; C

2007
Role of oxidative stress in hypertrophied myoblasts stimulated by isoproterenol.
    General thoracic and cardiovascular surgery, 2008, Volume: 56, Issue:4

    Topics: Animals; Apoptosis; Cardiomegaly; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Gluco

2008
Protein turnover in the in vitro perfused working rat heart.
    European heart journal, 1984, Volume: 5 Suppl F

    Topics: Animals; Aorta; Atrial Function; Blood Pressure; Cardiac Output; Cardiomegaly; Coronary Circulation;

1984
Ventricular fibrillation induced prior to cardioplegic arrest in hypertrophied pig hearts.
    The Annals of thoracic surgery, 1983, Volume: 36, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cardiomegaly; Creatine Kinase; Glycogen; Heart

1983
Abnormalities in myocardial perfusion during tachycardia in dogs with left ventricular hypertrophy: metabolic evidence for myocardial ischemia.
    Circulation, 1984, Volume: 69, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Cardiac Pacing, Artificial; Cardiomegaly; Coronary Circulation;

1984
Cardiac hypertrophy impairs recovery from ischaemia because there is a reduced reactive hyperaemic response.
    Cardiovascular research, 1995, Volume: 30, Issue:1

    Topics: Animals; Cardiomegaly; Coronary Circulation; Guinea Pigs; Hyperemia; Lactates; Lactic Acid; Male; My

1995
Improved protection of the hypertrophied left ventricle by histidine-containing cardioplegia.
    Circulation, 1995, Nov-01, Volume: 92, Issue:9 Suppl

    Topics: Animals; Cardiomegaly; Energy Metabolism; Heart; Heart Arrest, Induced; Histidine; Hydrogen-Ion Conc

1995
Ischemic dysfunction and impaired recovery in hypertensive hypertrophied hearts is associated with exaggerated intracellular sodium accumulation.
    American journal of hypertension, 1994, Volume: 7, Issue:8

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Hydrogen-Ion Concentration; Hypertension; Lactates; L

1994
Effect of endurance training on atrial natriuretic peptide gene expression in normal and hypertrophied hearts.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Blotting, Northern; Body Weight; Cardiomegaly; Dogs; Eating; Fem

1994
Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts.
    The American journal of physiology, 1994, Volume: 267, Issue:2 Pt 2

    Topics: Adenosine Triphosphate; Animals; Body Weight; Cardiomegaly; Energy Metabolism; Glucose; Glycolysis;

1994
Effects of brief repetitive ischemia on contractility, relaxation, and coronary flow. Exaggerated postischemic diastolic dysfunction in pressure-overload hypertrophy.
    Circulation research, 1993, Volume: 73, Issue:3

    Topics: Animals; Cardiomegaly; Coronary Circulation; Diastole; Glycolysis; Lactates; Lactic Acid; Male; Myoc

1993
Recovery of glycolysis and oxidative metabolism during postischemic reperfusion of hypertrophied rat hearts.
    The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 2

    Topics: Adenosine Triphosphate; Animals; Aorta; Cardiomegaly; Constriction; Glucose; Glycolysis; Heart; Home

1996
Spinal muscular atrophy-like picture, cardiomyopathy, and cytochrome c oxidase deficiency.
    Neurology, 1999, Jan-15, Volume: 52, Issue:2

    Topics: Blotting, Western; Cardiomegaly; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Fibroblasts; Huma

1999
Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cardiomegaly; Carrier Proteins; Disease Models, Anima

1999
Metabolic adaptation of the hypertrophied heart: role of the malate/aspartate and alpha-glycerophosphate shuttles.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12

    Topics: Adenosine Triphosphate; Animals; Aorta; Aspartic Acid; Atrial Natriuretic Factor; Blotting, Northern

2000
[An autopsy case of neonatal lactic acidosis].
    Pathologica, 2001, Volume: 93, Issue:1

    Topics: Acidosis, Lactic; Atrophy; Autopsy; Body Fluids; Brain; Cardiomegaly; Epilepsy, Generalized; Fatal O

2001
Temperature-induced changes in anaerobic capacity of interventricular septum in trained young and middle-aged rats.
    Biogerontology, 2002, Volume: 3, Issue:3

    Topics: Aging; Anaerobiosis; Animals; Cardiomegaly; Heart; Heart Septum; Heart Ventricles; Isoenzymes; L-Lac

2002
Impaired cardiopulmonary response to exercise in moderate hypertension.
    The Canadian journal of cardiology, 1992, Volume: 8, Issue:4

    Topics: Adult; Cardiomegaly; Exercise; Exercise Test; Female; Hemodynamics; Humans; Hypertension; Lactates;

1992
Protection of the hypertrophied myocardium by crystalloid cardioplegia.
    The Journal of surgical research, 1991, Volume: 51, Issue:6

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Creatine Kinase; Crystalloid Solutions; Heart Ar

1991
Effects of regression of left ventricular hypertrophy following atenolol or bunazosin therapy on ischemic cardiac function and myocardial metabolism in spontaneously hypertensive rats.
    Japanese circulation journal, 1991, Volume: 55, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atenolol; Blood Pre

1991
Influence of glucose and insulin on the exaggerated diastolic and systolic dysfunction of hypertrophied rat hearts during hypoxia.
    Circulation research, 1990, Volume: 66, Issue:2

    Topics: Animals; Cardiomegaly; Diastole; Glucose; Heart; Hypoxia; Insulin; Lactates; Lactic Acid; Male; Osmo

1990
Tolerance of the hypertrophic heart to ischemia. Studies in compensated and failing dog hearts with pressure overload hypertrophy.
    Circulation, 1990, Volume: 81, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Dogs; Heart Arrest, Induced; He

1990
Increased ischemic injury but decreased hypoxic injury in hypertrophied rat hearts.
    Circulation research, 1990, Volume: 67, Issue:4

    Topics: Adenosine Triphosphate; Animals; Aorta; Cardiomegaly; Constriction; Coronary Disease; Glycogen; Hear

1990
Protection of the hypertrophied human heart by adjusting regional myocardial temperature to a safe level.
    The Thoracic and cardiovascular surgeon, 1985, Volume: 33, Issue:4

    Topics: Adenosine Triphosphate; Aortic Valve; Bicarbonates; Calcium Chloride; Cardiomegaly; Female; Glucose;

1985
Regulation of ventricular atrial natriuretic peptide release in hypertrophied rat myocardium. Effects of exercise.
    Circulation, 1989, Volume: 80, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Cardiomegaly; Catecholamines; Heart Ventricles; Hypertension; La

1989
Effects of beta 1- and beta 1 + beta 2-antagonists on training-induced myocardial hypertrophy and enzyme adaptation.
    Biochemical pharmacology, 1987, Oct-15, Volume: 36, Issue:20

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; B

1987
Energy metabolism and mechanical function in perfused hearts of Syrian hamsters with dilated or hypertrophic cardiomyopathy.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:3

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Carnitine; Coenzyme A; Coronary Circu

1986
Impaired left ventricular postischemic function and metabolism in chronic right ventricular hypertrophy.
    Circulation, 1987, Volume: 76, Issue:5 Pt 2

    Topics: Adenosine Triphosphate; Animals; Cardiac Volume; Cardiomegaly; Chronic Disease; Coronary Circulation

1987
Reduced training intensities and loss of aerobic power, endurance, and cardiac growth.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:2

    Topics: Adaptation, Physiological; Adult; Body Weight; Cardiomegaly; Echocardiography; Female; Heart; Heart

1985