lactic acid has been researched along with Cardiac Remodeling, Ventricular in 18 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Left ventricular remodeling was ameliorated 28 days after IR, but the treatment did not affect inflammatory monocyte recruitment to the IR heart." | 1.43 | Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening. ( Egashira, K; Funamoto, D; Ikeda, G; Ishikita, A; Matoba, T; Nagaoka, K; Nakano, K; Nakano, Y; Sunagawa, K, 2016) |
| "Cardiac functional deterioration in dilated cardiomyopathy (DCM) is known to be reversed by intramyocardial up-regulation of multiple cardioprotective factors, whereas a prostacyclin analog, ONO1301, has been shown to paracrinally activate interstitial cells to release a variety of protective factors." | 1.39 | A slow-releasing form of prostacyclin agonist (ONO1301SR) enhances endogenous secretion of multiple cardiotherapeutic cytokines and improves cardiac function in a rapid-pacing-induced model of canine heart failure. ( Daimon, T; Fukushima, S; Kawaguchi, N; Matsuura, N; Miyagawa, S; Nakatani, S; Okita, Y; Saito, A; Sakai, Y; Sawa, Y; Shiozaki, M; Shirasaka, T, 2013) |
| "and results Left ventricular hypertrophy was induced surgically in Sprague-Dawley rats by inter-renal aortic constriction." | 1.35 | Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy. ( Akki, A; Seymour, AM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Schnelle, M | 1 |
| Chong, M | 1 |
| Zoccarato, A | 1 |
| Elkenani, M | 1 |
| Sawyer, GJ | 1 |
| Hasenfuss, G | 1 |
| Ludwig, C | 1 |
| Shah, AM | 1 |
| Jamaiyar, A | 1 |
| Wan, W | 1 |
| Ohanyan, V | 1 |
| Enrick, M | 1 |
| Janota, D | 1 |
| Cumpston, D | 1 |
| Song, H | 1 |
| Stevanov, K | 1 |
| Kolz, CL | 1 |
| Hakobyan, T | 1 |
| Dong, F | 1 |
| Newby, BZ | 1 |
| Chilian, WM | 1 |
| Yin, L | 1 |
| Zhao, Q | 1 |
| Sun, Q | 1 |
| Zhou, L | 1 |
| Liu, K | 1 |
| Jiao, K | 1 |
| Xu, J | 1 |
| Xu, X | 1 |
| Si, L | 1 |
| Xue, L | 1 |
| Zhang, S | 1 |
| Qin, J | 1 |
| Wu, Y | 1 |
| Shao, Y | 1 |
| Chen, Y | 1 |
| Wang, X | 1 |
| Cosmo, S | 1 |
| Francisco, JC | 1 |
| Cunha, RC | 1 |
| Macedo, RM | 1 |
| Faria-Neto, JR | 1 |
| Simeoni, R | 1 |
| Carvalho, KA | 1 |
| Olandoski, M | 1 |
| Miyague, NI | 1 |
| Amaral, VF | 1 |
| Guarita-Souza, LC | 1 |
| Shirasaka, T | 1 |
| Miyagawa, S | 1 |
| Fukushima, S | 1 |
| Saito, A | 1 |
| Shiozaki, M | 1 |
| Kawaguchi, N | 1 |
| Matsuura, N | 1 |
| Nakatani, S | 1 |
| Sakai, Y | 1 |
| Daimon, T | 1 |
| Okita, Y | 1 |
| Sawa, Y | 1 |
| Lu, ZX | 1 |
| Mao, LL | 1 |
| Lian, F | 1 |
| He, J | 1 |
| Zhang, WT | 1 |
| Dai, CY | 1 |
| Xue, S | 1 |
| Lu, WG | 1 |
| Zhu, HS | 1 |
| Savi, M | 1 |
| Bocchi, L | 1 |
| Fiumana, E | 1 |
| Karam, JP | 1 |
| Frati, C | 1 |
| Bonafé, F | 1 |
| Cavalli, S | 1 |
| Morselli, PG | 1 |
| Guarnieri, C | 1 |
| Caldarera, CM | 1 |
| Muscari, C | 1 |
| Montero-Menei, CN | 1 |
| Stilli, D | 1 |
| Quaini, F | 1 |
| Musso, E | 1 |
| Lee, YS | 1 |
| Joo, WS | 1 |
| Kim, HS | 1 |
| Kim, SW | 1 |
| Ikeda, G | 1 |
| Matoba, T | 2 |
| Nakano, Y | 1 |
| Nagaoka, K | 1 |
| Ishikita, A | 1 |
| Nakano, K | 2 |
| Funamoto, D | 1 |
| Sunagawa, K | 1 |
| Egashira, K | 2 |
| Ichimura, K | 1 |
| Tokutome, M | 1 |
| Honda, K | 1 |
| Koga, J | 1 |
| Akki, A | 1 |
| Seymour, AM | 2 |
| Alves, MG | 1 |
| Oliveira, PF | 1 |
| Martins, FO | 1 |
| Oliveira, PJ | 1 |
| Carvalho, RA | 1 |
| Mendes, OC | 1 |
| Sugizaki, MM | 1 |
| Campos, DS | 1 |
| Damatto, RL | 1 |
| Leopoldo, AS | 1 |
| Lima-Leopoldo, AP | 1 |
| Baldissera, V | 1 |
| Padovani, CR | 1 |
| Okoshi, K | 1 |
| Cicogna, AC | 1 |
| Sample, J | 1 |
| Cleland, JG | 1 |
| Verzola, RM | 1 |
| Mesquita, RA | 1 |
| Peviani, S | 1 |
| Ramos, OH | 1 |
| Moriscot, AS | 1 |
| Perez, SE | 1 |
| Selistre-de-Araújo, HS | 1 |
| Ingwall, JS | 1 |
| Neglia, D | 1 |
| De Caterina, A | 1 |
| Marraccini, P | 1 |
| Natali, A | 1 |
| Ciardetti, M | 1 |
| Vecoli, C | 1 |
| Gastaldelli, A | 1 |
| Ciociaro, D | 1 |
| Pellegrini, P | 1 |
| Testa, R | 1 |
| Menichetti, L | 1 |
| L'Abbate, A | 1 |
| Stanley, WC | 1 |
| Recchia, FA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Abnormal Glucose Tolerance is Associated With a Reduced Myocardial Metabolic Flexibility in Patients With Dilated Cardiomyopathy[NCT02440217] | 15 participants (Anticipated) | Observational | 2015-05-31 | Enrolling by invitation | |||
| Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy[NCT04222101] | 9 participants (Actual) | Interventional | 2019-10-07 | Terminated (stopped due to COVID-19 pandemic) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
18 other studies available for lactic acid and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
In vivo [U-
Topics: Animals; Blood Glucose; Carbon Isotopes; Citric Acid Cycle; Disease Models, Animal; Energy Metabolis | 2020 |
Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Coculture Techniq | 2017 |
Complex Regulation of Mitochondrial Function During Cardiac Development.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Enlargement; Cell Proliferation; Electron Transport Chain | 2019 |
Intracellular lactate signaling cascade in atrial remodeling of mitral valvular patients with atrial fibrillation.
Topics: Adult; Analysis of Variance; Apoptosis; Atrial Fibrillation; Case-Control Studies; Caspases; Female; | 2013 |
Effect of exercise associated with stem cell transplantation on ventricular function in rats after acute myocardial infarction.
Topics: Analysis of Variance; Animals; Bone Marrow Transplantation; Collagen; Disease Models, Animal; Lactic | 2012 |
A slow-releasing form of prostacyclin agonist (ONO1301SR) enhances endogenous secretion of multiple cardiotherapeutic cytokines and improves cardiac function in a rapid-pacing-induced model of canine heart failure.
Topics: Animals; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Cardiovascula | 2013 |
Cardioprotective activity of placental growth factor in a rat model of acute myocardial infarction: nanoparticle-based delivery versus direct myocardial injection.
Topics: Animals; Cardiotonic Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, | 2014 |
Enhanced engraftment and repairing ability of human adipose-derived stem cells, conveyed by pharmacologically active microcarriers continuously releasing HGF and IGF-1, in healing myocardial infarction in rats.
Topics: Adipose Tissue; Animals; Arrhythmias, Cardiac; Biomimetic Materials; Disease Models, Animal; Drug Ca | 2015 |
Human Mesenchymal Stem Cell Delivery System Modulates Ischemic Cardiac Remodeling With an Increase of Coronary Artery Blood Flow.
Topics: Animals; Cell Differentiation; Coronary Circulation; Humans; Imines; Lactic Acid; Male; Mesenchymal | 2016 |
Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening.
Topics: Animals; bcl-2-Associated X Protein; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Cytochromes | 2016 |
A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model.
Topics: Anesthesia; Animals; Blood Pressure; Cardiotonic Agents; Cell Death; Cells, Cultured; Consciousness; | 2016 |
Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy.
Topics: Acyl-CoA Dehydrogenase; Animals; CD36 Antigens; Diabetes Mellitus, Type 2; Dietary Fats; Disease Mod | 2009 |
Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution.
Topics: Alanine; Animals; Buffers; Cardioplegic Solutions; Cold Ischemia; Disaccharides; Electrolytes; Energ | 2012 |
Exercise tolerance in rats with aortic stenosis and ventricular diastolic and/or systolic dysfunction.
Topics: Animals; Aortic Valve Stenosis; Diastole; Echocardiography; Exercise Tolerance; Lactic Acid; Male; P | 2013 |
Metabolic remodeling in the aging heart.
Topics: Aging; Animals; Citrate (si)-Synthase; Fatty Acids; Glucose; Heart; In Vitro Techniques; L-Lactate D | 2006 |
Early remodeling of rat cardiac muscle induced by swimming training.
Topics: Animals; Blotting, Western; Body Weight; Gene Expression Regulation; Lactic Acid; Male; Matrix Metal | 2006 |
On substrate selection for ATP synthesis in the failing human myocardium.
Topics: Adenosine Triphosphate; Animals; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Coronary Circu | 2007 |
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy.
Topics: Aged; Carbon Isotopes; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; | 2007 |
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy.
Topics: Aged; Carbon Isotopes; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; | 2007 |
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy.
Topics: Aged; Carbon Isotopes; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; | 2007 |
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy.
Topics: Aged; Carbon Isotopes; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; | 2007 |