Page last updated: 2024-10-17

lactic acid and Cardiac Output, Low

lactic acid has been researched along with Cardiac Output, Low in 28 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.

Research Excerpts

ExcerptRelevanceReference
"Ranolazine was previously shown to stimulate cardiac glucose oxidation."5.29Effects of ranolazine on the exercise capacity of rats with chronic heart failure induced by myocardial infarction. ( Aaker, A; Hirai, T; McCormack, JG; Musch, TI, 1996)
"We describe a patient with carnitine-acylcarnitine translocase deficiency (MIM 212138), who presented with neonatal generalized seizures, heart failure, and coma."3.70Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle. ( Dorland, L; Duran, M; IJlst, L; Muntau, AC; Roscher, AA; Röschinger, W; Wanders, RJ, 2000)
"One patient in group T developed low cardiac output syndrome 48 hours after the operation and died after 1 month."2.71Markers of myocardial ischemia in the evaluation of the effect of left anterior descending coronary artery lesion and collateral circulation on myocardial injury in 1-vessel off-pump coronary bypass surgery. ( Alp, M; Güzelmeriç, F; Kayalar, N; Kirali, K; Mansuroğlu, D; Yakut, C, 2003)
"Low cardiac output syndrome is common after paediatric cardiac surgery."1.38Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery. ( de Jonge, E; Hazekamp, MG; Hogenbirk, K; Roest, AA; van Brempt, R; Verweij, EJ, 2012)
"Levosimendan produced an increase in cΔHbD (p < 0."1.37Acute effects of levosimendan on cerebral and systemic perfusion and oxygenation in newborns: an observational study. ( Bravo, MC; Bravo, Mdel C; Cabañas, F; López, P; Pellicer, A; Pérez-Fernández, E; Pérez-Rodríguez, J; Quero, J, 2011)
"Levosimendan is a calcium-sensitizing agent with effective inotropic properties."1.35First experiences with intraoperative Levosimendan in pediatric cardiac surgery. ( Boethig, D; Goerler, H; Huber, D; Osthaus, WA; Sasse, M; Sümpelmann, R; Winterhalter, M, 2009)
"Free carnitine levels were progressively decreased at 3 w (74% of control values) and at 6 w (57% of control values)."1.29Cardiac energy metabolism at several stages of adriamycin-induced heart failure in rats. ( Ishii, Y; Kawasaki, N; Lee, JD; Shimizu, H; Ueda, T, 1996)
"Ranolazine was previously shown to stimulate cardiac glucose oxidation."1.29Effects of ranolazine on the exercise capacity of rats with chronic heart failure induced by myocardial infarction. ( Aaker, A; Hirai, T; McCormack, JG; Musch, TI, 1996)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's10 (35.71)18.2507
2000's11 (39.29)29.6817
2010's5 (17.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Aslan, N1
Yıldızdaş, D1
Göçen, U1
Erdem, S1
Demir, F1
Yontem, A1
Horoz, ÖÖ1
Sertdemir, Y1
Park, SJ2
Kim, SP1
Kim, JB2
Jung, SH2
Choo, SJ2
Chung, CH2
Lee, JW2
Osthaus, WA1
Boethig, D1
Winterhalter, M1
Huber, D1
Goerler, H1
Sasse, M1
Sümpelmann, R1
Bravo, MC1
Bravo, Mdel C1
López, P1
Cabañas, F1
Pérez-Rodríguez, J1
Pérez-Fernández, E1
Quero, J1
Pellicer, A1
Onorati, F1
Santini, F1
Amoncelli, E1
Campanella, F1
Chiominto, B1
Faggian, G1
Mazzucco, A1
Verweij, EJ1
Hogenbirk, K1
Roest, AA1
van Brempt, R1
Hazekamp, MG1
de Jonge, E1
Myers, J1
Wagner, D1
Schertler, T1
Beer, M1
Luchinger, R1
Klein, M1
Rickli, H1
Muller, P1
Mayer, K1
Schwitter, J1
Dubach, P1
Hoffman, TM1
Wernovsky, G1
Atz, AM1
Kulik, TJ1
Nelson, DP1
Chang, AC1
Bailey, JM1
Akbary, A1
Kocsis, JF1
Kaczmarek, R1
Spray, TL1
Wessel, DL1
Kirali, K1
Mansuroğlu, D1
Kayalar, N1
Güzelmeriç, F1
Alp, M1
Yakut, C1
Middlekauff, HR1
Chiu, J1
Hamilton, MA1
Fonarow, GC1
Maclellan, WR1
Hage, A1
Moriguchi, J1
Patel, J1
Zakynthinos, S1
Routsi, C1
Vassilakopoulos, T1
Kaltsas, P1
Zakynthinos, E1
Kazi, D1
Roussos, C1
Richard, C1
Teboul, JL1
Doutreleau, S1
Mettauer, B1
Piquard, F1
Schaefer, A1
Lonsdorfer, E1
Richard, R1
Geny, B1
Ruokonen, E1
Takala, J1
Kari, A1
Wilson, JR1
Mancini, DM1
Dunkman, WB1
Reading, JL1
Goodman, JM1
Plyley, MJ1
Floras, JS1
Liu, PP1
McLaughlin, PR1
Shephard, RJ1
Kawasaki, N1
Lee, JD1
Shimizu, H1
Ishii, Y1
Ueda, T1
Aaker, A1
McCormack, JG1
Hirai, T1
Musch, TI1
Wasserman, K2
Röschinger, W1
Muntau, AC1
Duran, M1
Dorland, L1
IJlst, L1
Wanders, RJ1
Roscher, AA1
Rao, V1
Ivanov, J1
Weisel, RD1
Cohen, G1
Borger, MA1
Mickle, DA1
Rackow, EC1
O'Neil, P1
Astiz, ME1
Carpati, CM1
Pawelczyk, JA1
Hanel, B1
Pawelczyk, RA1
Warberg, J1
Secher, NH1
Cilley, RE1
Scharenberg, AM1
Bongiorno, PF1
Guire, KE1
Bartlett, RH1
Cohen-Solal, A1
Benessiano, J1
Himbert, D1
Paillole, C1
Gourgon, R1
Cryer, HG1
Mavroudis, C1
Yu, J1
Roberts, AM1
Cué, JI1
Richardson, JD1
Polk, HC1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Perioperative Levosimendan Administration in Neonates With Transposition of the Great Arteries: Randomized Controlled Trial[NCT01120106]Phase 263 participants (Actual)Interventional2009-01-31Completed
Phase I Study of Two Inodilators in Neonates Undergoing Cardiovascular Surgery[NCT01576094]Phase 1/Phase 220 participants (Actual)Interventional2009-11-30Completed
STeroids to REduce Systemic Inflammation After Infant Heart Surgery (STRESS)[NCT03229538]Phase 31,263 participants (Actual)Interventional2017-10-18Completed
Phase 2 Prospective, Randomized, Double-Blind Pilot Study on Cardiac Output Following Corrective Open Heart Surgery in Children Less Than One Year: Use of Levosimendan Versus Milrinone.[NCT00549107]Phase 240 participants (Anticipated)Interventional2007-09-30Recruiting
Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass[NCT00934843]77 participants (Actual)Interventional2007-03-31Completed
Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation[NCT02519335]Phase 112 participants (Actual)Interventional2014-09-30Terminated (stopped due to PI no longer at this facility)
2- Inhaled Milrinone Prevents the Increase in Pulmonary Artery Pressure After CPB[NCT00819377]Phase 2124 participants (Anticipated)Interventional2009-02-28Completed
Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery[NCT04997291]Phase 112 participants (Anticipated)Interventional2021-04-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With a Post-operative Length of Stay Greater Than 90 Days

Calculated as discharge date minus surgery date. (NCT03229538)
Timeframe: Until hospital discharge, up to 4 months

InterventionParticipants (Count of Participants)
Methylprednisolone Arm18
Placebo Arm29

Number of Participants With Any Other Post-operative Complications From the Start of Study Drug Administration Until Hospital Discharge.

(NCT03229538)
Timeframe: Until hospital discharge, up to 4 months

InterventionParticipants (Count of Participants)
Methylprednisolone Arm237
Placebo Arm264

Number of Participants With Death or Major Complication as Defined by an Outcome in One of the 7 Highest Global Ranking Categories

The 7 highest global ranking categories range from 91 (postoperative length of hospital stay > 90 days) to 97 (operative mortality). (NCT03229538)
Timeframe: Until hospital discharge, up to 4 months

InterventionParticipants (Count of Participants)
Methylprednisolone Arm103
Placebo Arm122

Number of Participants With Mortality, Including In-hospital Mortality or Mortality After Hospital Discharge But Within 30 Days of the Last Dose of Study Drug

(NCT03229538)
Timeframe: up to 30 days

InterventionParticipants (Count of Participants)
Methylprednisolone Arm12
Placebo Arm17

Number of Participants With Occurrence of Any One or More of the Following STS-CHSD-defined Major Post-operative Infectious Complications: Postprocedural Infective Endocarditis, Pneumonia, Sepsis, Deep Wound Infection, Mediastinitis.

(NCT03229538)
Timeframe: Until hospital discharge, up to 4 months

InterventionParticipants (Count of Participants)
Methylprednisolone Arm31
Placebo Arm24

Number of Participants With Post-operative Low Cardiac Output Syndrome

"Based upon the STS-CHSD registry defined cardiac dysfunction resulting in low cardiac output complication variable." (NCT03229538)
Timeframe: Until hospital discharge, up to 4 months

InterventionParticipants (Count of Participants)
Methylprednisolone Arm31
Placebo Arm37

Number of Participants With Prolonged Mechanical Ventilation (Greater Than 7 Days)

(NCT03229538)
Timeframe: Until hospital discharge, up to 4 months

InterventionParticipants (Count of Participants)
Methylprednisolone Arm41
Placebo Arm51

Inotropic Score

The inotropic score was calculated by the equation using drug dosages in micrograms/kg/min, (dopamine+dobutamine) + (milrinonex10) + (epinephrinex100) and recorded hourly upon arrival to the ICUthrough 36 hours postoperatively. The highest score during this timeframe was recorded. This score converts dosages of commonly used inotropic medications into a score. The higher the score the more inotropic medications required. The minimum score would be zero indicating no inotropic medications were used. There is no maximum score. (NCT00934843)
Timeframe: over the first 36 hours after surgery

InterventionScores on a scale (Mean)
MP Single Dose14.4
MP Two Dose15.0

Number of Participants Who Died Between 36 Hours and 30 Days Following Cardiac Surgery

Number of participants who died of any cause between 36 hours and 30 days following cardiac surgery (NCT00934843)
Timeframe: at 36 hours and 30 days

Interventionparticipants (Number)
MP Single Dose1
MP Two Dose0

Primary Endpoint: Number of Participants With Low Cardiac Output Syndrome (LCOS) or Death at 36 Hours From Admission to the Intensive Care Unit (ICU) After Surgery.

The presence of low cardiac output syndrome (LCOS) was defined by the same definition used in the PRIMACORP study (Hoffman TM.et.al. Circulation 2003 107:996-1002). Specifically, if there were clinical signs and symptoms of low cardiac output (e.g., tachycardia, oliguria, cold extremities, cardiac arrest, etc.) which required one or more of the following interventions: mechanical circulatory support, the escalation of existing pharmacological circulatory support to >100% over baseline, or the initiation of new pharmacological circulatory support. (NCT00934843)
Timeframe: 36 hours

Interventionparticipants (Number)
MP Single Dose17
MP Two Dose15

Urine Output

Total urine output in mL over the first 36 hours after cardiac surgery (NCT00934843)
Timeframe: over 36 hours

InterventionmL (Mean)
MP Single Dose498
MP Two Dose453

Total Intake/Output of Fluid

Total amount of all fluids in and out during the first 36 hours postoperatively in mL. (NCT00934843)
Timeframe: over 36 hours

,
InterventionmL (Mean)
Total Fluid in at 36 hrTotal Fluid out at 36 hr
MP Single Dose575600
MP Two Dose586558

Trials

6 trials available for lactic acid and Cardiac Output, Low

ArticleYear
How should I wean my next intra-aortic balloon pump? Differences between progressive volume weaning and rate weaning.
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 145, Issue:5

    Topics: Aged; Arterial Pressure; Biomarkers; Cardiac Output; Cardiac Output, Low; Central Venous Pressure; F

2013
Effects of exercise training on left ventricular volumes and function in patients with nonischemic cardiomyopathy: application of magnetic resonance myocardial tagging.
    American heart journal, 2002, Volume: 144, Issue:4

    Topics: Cardiac Output, Low; Exercise Therapy; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Male

2002
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Blood Pressure; Cardiac Output, Low; Child; Child, Preschool; Double-Blind Method; Endpoint Determin

2003
Markers of myocardial ischemia in the evaluation of the effect of left anterior descending coronary artery lesion and collateral circulation on myocardial injury in 1-vessel off-pump coronary bypass surgery.
    The heart surgery forum, 2003, Volume: 6, Issue:3

    Topics: Adult; Aged; Biomarkers; Cardiac Output, Low; Collateral Circulation; Coronary Artery Bypass; Corona

2003
Muscle mechanoreceptor sensitivity in heart failure.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:5

    Topics: Arm; Cardiac Output, Low; Constriction; Dichloroacetic Acid; Double-Blind Method; Exercise; Female;

2004
Regional blood flow and oxygen transport in patients with the low cardiac output syndrome after cardiac surgery.
    Critical care medicine, 1993, Volume: 21, Issue:9

    Topics: Body Temperature; Calorimetry, Indirect; Cardiac Output, Low; Coronary Artery Bypass; Dobutamine; Dr

1993

Other Studies

22 other studies available for lactic acid and Cardiac Output, Low

ArticleYear
[Low cardiac output syndrome score to evaluate postoperative cardiac surgery patients in a pediatric intensive care unit].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2020, Volume: 48, Issue:5

    Topics: Aorta; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child, Preschool; C

2020
Blood lactate level during extracorporeal life support as a surrogate marker for survival.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 148, Issue:2

    Topics: Adult; Aged; Area Under Curve; Biomarkers; Cardiac Output, Low; Cardiac Surgical Procedures; Chi-Squ

2014
First experiences with intraoperative Levosimendan in pediatric cardiac surgery.
    European journal of pediatrics, 2009, Volume: 168, Issue:6

    Topics: Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Heart; Heart D

2009
Acute effects of levosimendan on cerebral and systemic perfusion and oxygenation in newborns: an observational study.
    Neonatology, 2011, Volume: 99, Issue:3

    Topics: Blood Pressure; Cardiac Output, Low; Cardiotonic Agents; Cerebrovascular Circulation; Heart Defects,

2011
Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery.
    Interactive cardiovascular and thoracic surgery, 2012, Volume: 15, Issue:4

    Topics: Adrenal Insufficiency; Age Factors; Biomarkers; Blood Pressure; Cardiac Output, Low; Cardiac Surgica

2012
Outcomes of extracorporeal life support for low cardiac output syndrome after major cardiac surgery.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 147, Issue:1

    Topics: Adult; Aged; Anticoagulants; Area Under Curve; Benzamidines; Biomarkers; Cardiac Output, Low; Cardia

2014
Differential cardiovascular responses during weaning failure: effects on tissue oxygenation and lactate.
    Intensive care medicine, 2005, Volume: 31, Issue:12

    Topics: Aged; Aged, 80 and over; Cardiac Output; Cardiac Output, Low; Case-Control Studies; Female; Heart Fa

2005
Weaning failure from cardiovascular origin.
    Intensive care medicine, 2005, Volume: 31, Issue:12

    Topics: Cardiac Output, Low; Heart Failure; Humans; Lactic Acid; Oxygen; Pulmonary Disease, Chronic Obstruct

2005
Chronic but not acute oral L-arginine supplementation delays the ventilatory threshold during exercise in heart failure patients.
    Canadian journal of applied physiology = Revue canadienne de physiologie appliquee, 2005, Volume: 30, Issue:4

    Topics: Anaerobic Threshold; Arginine; Carbon Dioxide; Cardiac Output, Low; Drug Administration Schedule; Ex

2005
Exertional fatigue due to skeletal muscle dysfunction in patients with heart failure.
    Circulation, 1993, Volume: 87, Issue:2

    Topics: Adult; Arteries; Cardiac Output, Low; Fatigue; Femoral Vein; Humans; Lactates; Lactic Acid; Leg; Mal

1993
Vascular conductance and aerobic power in sedentary and active subjects and heart failure patients.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:2

    Topics: Adult; Aerobiosis; Blood Pressure; Cardiac Output; Cardiac Output, Low; Exercise Test; Fatigue; Fema

1993
Cardiac energy metabolism at several stages of adriamycin-induced heart failure in rats.
    International journal of cardiology, 1996, Volume: 55, Issue:3

    Topics: Adenosine Triphosphate; Alanine; Animals; Cardiac Output, Low; Carnitine; Chromatography, High Press

1996
Effects of ranolazine on the exercise capacity of rats with chronic heart failure induced by myocardial infarction.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:3

    Topics: Acetanilides; Animals; Blood Glucose; Cardiac Output, Low; Enzyme Inhibitors; Female; Glycogen; Lact

1996
Critical capillary PO2 and the role of lactate production in oxyhemoglobin dissociation during exercise.
    Advances in experimental medicine and biology, 1999, Volume: 471

    Topics: Acidosis, Lactic; Adult; Blood Gas Analysis; Buffers; Capillaries; Cardiac Output, Low; Exercise; Fe

1999
Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle.
    Clinica chimica acta; international journal of clinical chemistry, 2000, Volume: 298, Issue:1-2

    Topics: Ammonia; Cardiac Output, Low; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Coma; Consangu

2000
Lactate release during reperfusion predicts low cardiac output syndrome after coronary bypass surgery.
    The Annals of thoracic surgery, 2001, Volume: 71, Issue:6

    Topics: Aged; Cardiac Output, Low; Coronary Artery Bypass; Creatine Kinase; Creatine Kinase, MB Form; Female

2001
Sublingual capnometry and indexes of tissue perfusion in patients with circulatory failure.
    Chest, 2001, Volume: 120, Issue:5

    Topics: APACHE; Blood Circulation; Capnography; Carbon Dioxide; Cardiac Output, Low; Gastric Mucosa; Hemodyn

2001
Leg vasoconstriction during dynamic exercise with reduced cardiac output.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:5

    Topics: Adult; Blood Gas Analysis; Cardiac Output, Low; Catecholamines; Exercise; Female; Heart Rate; Humans

1992
Low oxygen delivery produced by anemia, hypoxia, and low cardiac output.
    The Journal of surgical research, 1991, Volume: 51, Issue:5

    Topics: Anemia; Animals; Cardiac Output, Low; Dogs; Hypoxia; Lactates; Lactic Acid; Oxygen Consumption; Ther

1991
Ventilatory threshold during exercise in patients with mild to moderate chronic heart failure: determination, relation with lactate threshold and reproducibility.
    International journal of cardiology, 1991, Volume: 30, Issue:3

    Topics: Adult; Aged; Breath Tests; Carbon Dioxide; Cardiac Output, Low; Exercise Test; Humans; Lactates; Lac

1991
Shock, transfusion, and pneumonectomy. Death is due to right heart failure and increased pulmonary vascular resistance.
    Annals of surgery, 1990, Volume: 212, Issue:2

    Topics: Animals; Blood Pressure; Blood Transfusion; Cardiac Output; Cardiac Output, Low; Heart; Lactates; La

1990
The peripheral circulation and lactic acid metabolism in heart, or cardiovascular, failure.
    Circulation, 1989, Volume: 80, Issue:4

    Topics: Blood Circulation; Blood Vessels; Cardiac Output; Cardiac Output, Low; Cardiovascular System; Glycog

1989