lactic acid has been researched along with Carcinoma in 45 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate the potential cardioprotective and anti-cancer effects of carvedilol (CAR) either free or as loaded nano-formulated with or without doxorubicin (DOX) in solid Ehrlich carcinoma (SEC)-bearing mice." | 8.31 | Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice. ( Abdin, AA; El Maghraby, GM; El Saadany, AA; Hedya, SE; Zidan, A, 2023) |
| "HIF-1α is highly expressed in the esophageal carcinoma cell lines tested, and with decreasing levels of oxygen, the expression of HIF-1α and the associated glycolytic enzymes and the extracellular lactic acid concentration were enhanced in the esophageal carcinoma cell lines Eca109 and TE13." | 7.83 | Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. ( Feng, YD; Hao, B; He, GJ; Tang, NN; Zeng, L; Zhang, WF; Zhou, HY; Zhu, H, 2016) |
| "The transferring modified lipid coated PLGA nanoparticles, as a targetable vector, were developed for the targeting delivery of anticancer drugs with paclitaxel (PTX) as a model drug to the ovarian carcinoma, which combines the advantages and avoids disadvantages of polymeric nanoparticles and liposomes in drug delivery." | 7.80 | A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles. ( Chen, XG; He, YX; Li, R; Wang, XY; Yang, WY; Yang, X; Zhang, Q, 2014) |
| "In this study we characterized (3)H-2-deoxy-d-glucose ((3)H -DG) uptake by the estrogen receptor (ER)-positive MCF7 and the ER-negative MDA-MB-231 human breast cancer cell lines and investigated the effect of quercetin (QUE) and epigallocatechin gallate (EGCG) upon (3)H-DG uptake, glucose metabolism and cell viability and proliferation." | 7.79 | Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism. ( Araújo, I; Correia-Branco, A; Costa, T; Faria, A; Keating, E; Martel, F; Moreira, L, 2013) |
| "A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors." | 5.37 | Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011) |
| "The aim of this study was to investigate the potential cardioprotective and anti-cancer effects of carvedilol (CAR) either free or as loaded nano-formulated with or without doxorubicin (DOX) in solid Ehrlich carcinoma (SEC)-bearing mice." | 4.31 | Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice. ( Abdin, AA; El Maghraby, GM; El Saadany, AA; Hedya, SE; Zidan, A, 2023) |
| " Subsequently, we examined the effects of CYC1 on proliferation, glycolysis and chemosensitivity to paclitaxel, which is one of the most common chemotherapeutic agents in breast cancer, in ER-positive breast carcinoma cells (MCF7 and T47D)." | 3.91 | Cytochrome c1 as a favorable prognostic marker in estrogen receptor-positive breast carcinoma. ( Hara, M; Ishida, T; Miki, Y; Sasano, H; Sato, A; Suzuki, T; Takagi, K; Yoshimura, A, 2019) |
| "HIF-1α is highly expressed in the esophageal carcinoma cell lines tested, and with decreasing levels of oxygen, the expression of HIF-1α and the associated glycolytic enzymes and the extracellular lactic acid concentration were enhanced in the esophageal carcinoma cell lines Eca109 and TE13." | 3.83 | Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. ( Feng, YD; Hao, B; He, GJ; Tang, NN; Zeng, L; Zhang, WF; Zhou, HY; Zhu, H, 2016) |
| "The transferring modified lipid coated PLGA nanoparticles, as a targetable vector, were developed for the targeting delivery of anticancer drugs with paclitaxel (PTX) as a model drug to the ovarian carcinoma, which combines the advantages and avoids disadvantages of polymeric nanoparticles and liposomes in drug delivery." | 3.80 | A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles. ( Chen, XG; He, YX; Li, R; Wang, XY; Yang, WY; Yang, X; Zhang, Q, 2014) |
| "In this study we characterized (3)H-2-deoxy-d-glucose ((3)H -DG) uptake by the estrogen receptor (ER)-positive MCF7 and the ER-negative MDA-MB-231 human breast cancer cell lines and investigated the effect of quercetin (QUE) and epigallocatechin gallate (EGCG) upon (3)H-DG uptake, glucose metabolism and cell viability and proliferation." | 3.79 | Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism. ( Araújo, I; Correia-Branco, A; Costa, T; Faria, A; Keating, E; Martel, F; Moreira, L, 2013) |
| "The aim of this work was to prepare paclitaxel-loaded PLGA nanoparticles and determine cytotoxicity of released paclitaxel for two hypoxic human tumor cell lines: breast carcinoma (MCF-7) and carcinoma cervicis (HeLa)." | 3.75 | Cytotoxicity of paclitaxel incorporated in PLGA nanoparticles on hypoxic human tumor cells. ( Bai, L; Dou, K; Guo, G; Jin, C; Song, W; Wu, H, 2009) |
| "MCT4 and Cav-1 are also breast cancer prognostic biomarkers." | 2.50 | Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function. ( Lisanti, MP; Martinez-Outschoorn, U; Sotgia, F, 2014) |
| "TIGAR downregulation in breast carcinoma cells reduces tumor growth." | 1.91 | TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer. ( Bartrons, R; Birbe, RC; Caro, J; Domingo-Vidal, M; Győrffy, B; Ko, YH; Lin, Z; Martinez-Outschoorn, U; Philp, NJ; Roche, ME; Tuluc, M; Whitaker-Menezes, D, 2023) |
| "IP glycerol was only moderately indicative for ischemia after 91-120 minutes with 0,791 ROC AUCs (threshold 122 μmol/l)." | 1.39 | Validation of intraluminal and intraperitoneal microdialysis in ischemic small intestine. ( Minkkinen, M; Nordback, I; Perner, A; Pynnönen, L; Räty, S; Sand, J; Tenhunen, J, 2013) |
| "We have shown earlier that breast cancer cells secrete higher levels of interleukin-6 (IL-6) under hypoxia, leading to the recruitment of hMSCs towards hypoxic tumor cells." | 1.38 | Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. ( Ackerstaff, E; Banerjee, D; Glod, JW; Koutcher, JA; Patel, BB; Rattigan, YI; Sukenick, G, 2012) |
| "A high lactate content in malignant head and neck cancer (Head and neck squamous cell carcinomas, HNSCC) is associated with a higher risk of metastatic spread and lower overall patient survival." | 1.37 | Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue. ( Kunkel, M; Mueller-Klieser, W; Reichert, TE; Wagner, W; Walenta, S; Ziebart, T, 2011) |
| "A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors." | 1.37 | Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011) |
| " Sustained release nanoparticles (NP) offer increased resistance to nuclease degradation, increased amounts of AS uptake, and the possibility of control in dosing and sustained duration of AS administration." | 1.36 | Biodistribution of antisense nanoparticles in mammary carcinoma rat model. ( Adwan, H; Berger, MR; Elazar, V; Golomb, G; Lifshitz-Shovali, R; Rohekar, K; Zepp, M, 2010) |
| "Colon carcinoma is one of the common malignant tumors and has high morbidity and mortality in the world." | 1.36 | The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma. ( Cui, FY; Li, SZ; Li, ZY; Mao, YQ; Mu, B; Song, XR; Wei, YQ; Yang, L, 2010) |
| "The glucose uptake rate of human mammary carcinomas transplanted into nude rats is comparable to values obtained in isotransplanted rodent tumors." | 1.27 | Glucose, lactate, and ketone body utilization by human mammary carcinomas in vivo. ( Baessler, KH; Davel, S; Kallinowskil, F; Vaupell, P; Wagner, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.33) | 18.7374 |
| 1990's | 1 (2.22) | 18.2507 |
| 2000's | 3 (6.67) | 29.6817 |
| 2010's | 32 (71.11) | 24.3611 |
| 2020's | 3 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zidan, A | 1 |
| El Saadany, AA | 1 |
| El Maghraby, GM | 1 |
| Abdin, AA | 1 |
| Hedya, SE | 1 |
| Roche, ME | 1 |
| Ko, YH | 1 |
| Domingo-Vidal, M | 1 |
| Lin, Z | 1 |
| Whitaker-Menezes, D | 1 |
| Birbe, RC | 1 |
| Tuluc, M | 1 |
| Győrffy, B | 1 |
| Caro, J | 1 |
| Philp, NJ | 1 |
| Bartrons, R | 1 |
| Martinez-Outschoorn, U | 2 |
| Chang, M | 1 |
| Ellmaker, K | 1 |
| Esposito, A | 1 |
| Lauricella, A | 1 |
| Pa, S | 1 |
| Roberts, M | 1 |
| Kurt, RA | 1 |
| Su, Y | 1 |
| Yu, QH | 1 |
| Wang, XY | 2 |
| Yu, LP | 1 |
| Wang, ZF | 1 |
| Cao, YC | 1 |
| Li, JD | 1 |
| Zhu, JM | 1 |
| Quan, XL | 1 |
| Han, SC | 1 |
| Fan, XJ | 1 |
| Li, HM | 1 |
| Liang, SS | 1 |
| Chen, X | 1 |
| Wang, RY | 1 |
| Ji, XN | 1 |
| Sato, A | 1 |
| Takagi, K | 1 |
| Miki, Y | 1 |
| Yoshimura, A | 1 |
| Hara, M | 1 |
| Ishida, T | 1 |
| Sasano, H | 1 |
| Suzuki, T | 1 |
| Moreira, L | 1 |
| Araújo, I | 1 |
| Costa, T | 1 |
| Correia-Branco, A | 1 |
| Faria, A | 1 |
| Martel, F | 1 |
| Keating, E | 1 |
| Gottfried, E | 1 |
| Lang, SA | 1 |
| Renner, K | 1 |
| Bosserhoff, A | 1 |
| Gronwald, W | 1 |
| Rehli, M | 1 |
| Einhell, S | 1 |
| Gedig, I | 1 |
| Singer, K | 1 |
| Seilbeck, A | 1 |
| Mackensen, A | 1 |
| Grauer, O | 1 |
| Hau, P | 1 |
| Dettmer, K | 1 |
| Andreesen, R | 1 |
| Oefner, PJ | 1 |
| Kreutz, M | 1 |
| Li, X | 1 |
| Lu, W | 1 |
| Hu, Y | 1 |
| Wen, S | 1 |
| Qian, C | 1 |
| Wu, W | 1 |
| Huang, P | 1 |
| Pynnönen, L | 1 |
| Minkkinen, M | 1 |
| Perner, A | 1 |
| Räty, S | 1 |
| Nordback, I | 1 |
| Sand, J | 1 |
| Tenhunen, J | 1 |
| Li, R | 1 |
| Zhang, Q | 2 |
| Chen, XG | 1 |
| He, YX | 1 |
| Yang, WY | 1 |
| Yang, X | 1 |
| Xiao, L | 1 |
| Hu, ZY | 1 |
| Dong, X | 1 |
| Tan, Z | 1 |
| Li, W | 1 |
| Tang, M | 1 |
| Chen, L | 1 |
| Yang, L | 2 |
| Tao, Y | 1 |
| Jiang, Y | 1 |
| Li, J | 1 |
| Yi, B | 1 |
| Li, B | 1 |
| Fan, S | 1 |
| You, S | 1 |
| Deng, X | 1 |
| Hu, F | 2 |
| Feng, L | 2 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Sun, LQ | 1 |
| Cao, Y | 1 |
| Sotgia, F | 1 |
| Lisanti, MP | 1 |
| Punfa, W | 1 |
| Suzuki, S | 1 |
| Pitchakarn, P | 1 |
| Yodkeeree, S | 1 |
| Naiki, T | 1 |
| Takahashi, S | 1 |
| Limtrakul, P | 1 |
| Demmel, F | 1 |
| Brischwein, M | 1 |
| Wolf, P | 1 |
| Huber, F | 1 |
| Pfister, C | 1 |
| Wolf, B | 1 |
| Giannoni, E | 1 |
| Taddei, ML | 1 |
| Morandi, A | 1 |
| Comito, G | 1 |
| Calvani, M | 1 |
| Bianchini, F | 1 |
| Richichi, B | 1 |
| Raugei, G | 1 |
| Wong, N | 1 |
| Tang, D | 1 |
| Chiarugi, P | 1 |
| Bol, GM | 1 |
| Khan, R | 1 |
| Heerma van Voss, MR | 1 |
| Tantravedi, S | 1 |
| Korz, D | 1 |
| Kato, Y | 1 |
| Raman, V | 1 |
| Sandulache, VC | 2 |
| Chen, Y | 1 |
| Skinner, HD | 1 |
| Lu, T | 1 |
| Court, LE | 1 |
| Myers, JN | 2 |
| Meyn, RE | 1 |
| Fuller, CD | 1 |
| Bankson, JA | 1 |
| Lai, SY | 1 |
| Pow, EH | 1 |
| Chen, Z | 1 |
| Kwong, DL | 1 |
| Lam, OL | 1 |
| Zeng, L | 1 |
| Zhou, HY | 1 |
| Tang, NN | 1 |
| Zhang, WF | 1 |
| He, GJ | 1 |
| Hao, B | 1 |
| Feng, YD | 1 |
| Zhu, H | 1 |
| Liang, G | 1 |
| Zhu, Y | 1 |
| Jing, A | 1 |
| Wang, J | 1 |
| Feng, W | 1 |
| Xiao, Z | 1 |
| Chen, B | 1 |
| Dai, Z | 1 |
| Shestov, AA | 1 |
| Lai, L | 1 |
| Locasale, JW | 1 |
| Gao, J | 1 |
| Li, L | 1 |
| Chen, HB | 1 |
| Li, XQ | 1 |
| Yan, XZ | 1 |
| Jin, C | 1 |
| Bai, L | 1 |
| Wu, H | 1 |
| Song, W | 1 |
| Guo, G | 1 |
| Dou, K | 1 |
| Bertuzzi, A | 1 |
| Fasano, A | 1 |
| Gandolfi, A | 1 |
| Sinisgalli, C | 1 |
| Sabel, MS | 1 |
| Su, G | 1 |
| Griffith, KA | 1 |
| Chang, AE | 1 |
| Grotius, J | 1 |
| Dittfeld, C | 1 |
| Huether, M | 1 |
| Mueller-Klieser, W | 2 |
| Baumann, M | 1 |
| Kunz-Schughart, LA | 1 |
| Robinson, R | 1 |
| Bertram, JP | 1 |
| Reiter, JL | 1 |
| Lavik, EB | 1 |
| Ziebart, T | 1 |
| Walenta, S | 1 |
| Kunkel, M | 1 |
| Reichert, TE | 1 |
| Wagner, W | 1 |
| Elazar, V | 1 |
| Adwan, H | 1 |
| Rohekar, K | 1 |
| Zepp, M | 1 |
| Lifshitz-Shovali, R | 1 |
| Berger, MR | 1 |
| Golomb, G | 1 |
| Cui, FY | 1 |
| Song, XR | 1 |
| Li, ZY | 1 |
| Li, SZ | 1 |
| Mu, B | 1 |
| Mao, YQ | 1 |
| Wei, YQ | 1 |
| De Bari, L | 1 |
| Chieppa, G | 1 |
| Marra, E | 1 |
| Passarella, S | 1 |
| Hanlon, DJ | 1 |
| Aldo, PB | 1 |
| Devine, L | 1 |
| Alvero, AB | 1 |
| Engberg, AK | 1 |
| Edelson, R | 1 |
| Mor, G | 1 |
| Ow, TJ | 1 |
| Pickering, CR | 1 |
| Frederick, MJ | 1 |
| Zhou, G | 1 |
| Fokt, I | 1 |
| Davis-Malesevich, M | 1 |
| Priebe, W | 1 |
| Jeong, YI | 1 |
| Kim, DH | 1 |
| Chung, CW | 1 |
| Yoo, JJ | 1 |
| Choi, KH | 1 |
| Kim, CH | 1 |
| Ha, SH | 1 |
| Kang, DH | 1 |
| Hansen, RA | 1 |
| Anderson, C | 1 |
| Fettman, MJ | 1 |
| Larue, SM | 1 |
| Davenport, DJ | 1 |
| Gross, KL | 1 |
| Richardson, KL | 1 |
| Ogilvie, GK | 1 |
| Rattigan, YI | 1 |
| Patel, BB | 1 |
| Ackerstaff, E | 1 |
| Sukenick, G | 1 |
| Koutcher, JA | 1 |
| Glod, JW | 1 |
| Banerjee, D | 1 |
| Terakawa, M | 1 |
| Tsunoi, Y | 1 |
| Mitsuhashi, T | 1 |
| WILSON, HT | 1 |
| LAZARONI, JA | 1 |
| MAIER, EC | 1 |
| BUBANI, V | 1 |
| CHEN, FW | 1 |
| Armstrong, CP | 1 |
| Dent, DM | 1 |
| Berman, P | 1 |
| Aitken, RJ | 1 |
| Rijksen, G | 1 |
| Oskam, R | 1 |
| Molthoff, CF | 1 |
| Lee On, SJ | 1 |
| Streefkerk, M | 1 |
| Staal, GE | 1 |
| Yanai, S | 1 |
| Okada, H | 1 |
| Saito, K | 1 |
| Kuge, Y | 1 |
| Misaki, M | 1 |
| Ogawa, Y | 1 |
| Toguchi, H | 1 |
| Kallinowskil, F | 1 |
| Davel, S | 1 |
| Vaupell, P | 1 |
| Baessler, KH | 1 |
| Wagner, K | 1 |
1 review available for lactic acid and Carcinoma
| Article | Year |
|---|---|
Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
Topics: Animals; Autophagy; Breast Neoplasms; Cachexia; Carcinoma; Caveolin 1; Cell Line, Tumor; Cell Transf | 2014 |
1 trial available for lactic acid and Carcinoma
| Article | Year |
|---|---|
Menhaden oil administration to dogs treated with radiation for nasal tumors demonstrates lower levels of tissue eicosanoids.
Topics: Animals; Carcinoma; Dietary Fats; Dogs; Double-Blind Method; Eicosanoids; Energy Metabolism; Fish Oi | 2011 |
43 other studies available for lactic acid and Carcinoma
| Article | Year |
|---|---|
Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice.
Topics: Animals; Carcinoma; Carvedilol; Doxorubicin; Female; Lactic Acid; Liposomes; Mice; Nanoparticles; Va | 2023 |
TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Female; Gly | 2023 |
The Impact of Tumor-Associated Macrophages Found at Mammary Carcinoma Sites is Dependent Upon the Tumor Type.
Topics: AMP-Activated Protein Kinases; Carcinoma; Glucose Transporter Type 1; Humans; Lactic Acid; Tumor-Ass | 2023 |
JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression.
Topics: Adenosine Triphosphate; Adult; Aged; Biomarkers; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Pr | 2017 |
Establishment of a Model of Microencapsulated SGC7901 Human Gastric Carcinoma Cells Cocultured with Tumor-Associated Macrophages.
Topics: Carcinoma; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Glucose; Humans; Lactic Acid; | 2018 |
Cytochrome c1 as a favorable prognostic marker in estrogen receptor-positive breast carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast; Breast Neoplasms; Carcinoma; Cell Line, T | 2019 |
Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Catechin; Cell Death; Cell Proliferation; Female | 2013 |
New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carcinoma; Cell Line, Tumor; | 2013 |
Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Carcinoma; Cell Cycle; Cell Prolifera | 2013 |
Validation of intraluminal and intraperitoneal microdialysis in ischemic small intestine.
Topics: Aged; Carcinoma; Female; Glucose; Glycerol; Humans; Intestine, Small; Ischemia; Lactic Acid; Male; M | 2013 |
A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Chemistry, Pharmaceutical; | 2014 |
Targeting Epstein-Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy.
Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulatio | 2014 |
Curcumin-loaded PLGA nanoparticles conjugated with anti- P-glycoprotein antibody to overcome multidrug resistance.
Topics: Animals; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette | 2014 |
Nutrient depletion and metabolic profiles in breast carcinoma cell lines measured with a label-free platform.
Topics: Actins; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Cytocha | 2015 |
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.
Topics: Active Transport, Cell Nucleus; Animals; Binding Sites; Carcinoma; Carrier Proteins; Cell Line, Tumo | 2015 |
PLGA nanoparticle formulation of RK-33: an RNA helicase inhibitor against DDX3.
Topics: Animals; Antineoplastic Agents; Azepines; Breast Neoplasms; Carcinoma; Cell Survival; Delayed-Action | 2015 |
Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model.
Topics: Animals; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Line, Tu | 2015 |
Salivary Anionic Changes after Radiotherapy for Nasopharyngeal Carcinoma: A 1-Year Prospective Study.
Topics: Acetates; Adult; Aged; Anions; Carcinoma; Chlorides; Female; Formates; Humans; Hydrogen-Ion Concentr | 2016 |
Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
Topics: Androstadienes; Carcinoma; Cell Line, Tumor; Esophageal Neoplasms; Gene Expression Regulation, Neopl | 2016 |
Cationic microRNA-delivering nanocarriers for efficient treatment of colon carcinoma in xenograft model.
Topics: Animals; Apoptosis; Carcinoma; Colonic Neoplasms; G1 Phase Cell Cycle Checkpoints; Genetic Vectors; | 2016 |
A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.
Topics: Adenosine Triphosphate; Algorithms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferatio | 2016 |
[Metabonomic study of blood plasma in the assessment of liver graft function].
Topics: Acetone; Alanine; Biomarkers; Blood Glucose; Carcinoma; Choline; Glutamine; Humans; Lactic Acid; Liv | 2007 |
Cytotoxicity of paclitaxel incorporated in PLGA nanoparticles on hypoxic human tumor cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma; Cell Hypoxia; Cell Survival | 2009 |
Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?
Topics: Adenosine Triphosphate; Animals; Carcinoma; Dose-Response Relationship, Drug; Energy Metabolism; Fem | 2010 |
Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-alpha in a model of metastatic breast cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; CD4-Positive T-Lymphocytes; CD8- | 2010 |
Impact of exogenous lactate on survival and radioresponse of carcinoma cells in vitro.
Topics: Acidosis; Basigin; Carcinoma; Cell Line, Tumor; Cell Survival; Glucose; HCT116 Cells; HT29 Cells; Hu | 2009 |
New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres.
Topics: Animals; Carcinoma; Cell Line; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Humans; Lactic A | 2010 |
Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Blotting, Western; Carcin | 2011 |
Biodistribution of antisense nanoparticles in mammary carcinoma rat model.
Topics: Animals; Antineoplastic Agents; Antisense Elements (Genetics); Bone Neoplasms; Carcinoma; Cell Line, | 2010 |
The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma.
Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dependovirus | 2010 |
L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.
Topics: Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; L-Lactate Dehydrogena | 2010 |
Enhanced stimulation of anti-ovarian cancer CD8(+) T cells by dendritic cells loaded with nanoparticle encapsulated tumor antigen.
Topics: Antigen Presentation; Antigens, Differentiation; Antigens, Neoplasm; Carcinoma; CD8-Positive T-Lymph | 2011 |
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Prol | 2011 |
Self-assembled nanoparticles of hyaluronic acid/poly(DL-lactide-co-glycolide) block copolymer.
Topics: Antineoplastic Agents; Binding, Competitive; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Delayed | 2012 |
Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment.
Topics: Breast Neoplasms; Carcinoma; Cell Communication; Cell Line, Tumor; Female; Fibroblasts; Glycolysis; | 2012 |
In vitro perforation of human epithelial carcinoma cell with antibody-conjugated biodegradable microspheres illuminated by a single 80 femtosecond near-infrared laser pulse.
Topics: Antibodies; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Membrane; Drug Delivery Systems | 2012 |
A test for myocardial infarction; the present status of the use of serum lactic acid dehydrogenase.
Topics: Carcinoma; Clinical Enzyme Tests; Humans; L-Lactate Dehydrogenase; Lactic Acid; Law Enforcement; Myo | 1958 |
[Study of the blood levels of lactic acid in patients with genital carcinoma treated with cobalt 60 teletherapy].
Topics: Carcinoma; Cobalt; Cobalt Radioisotopes; Genitalia; Genitalia, Female; Humans; Lactates; Lactic Acid | 1959 |
[Experimental study on the diagnosis of primary carcinoma of the liver. (Ratio of liver homogenate lactic acid dehydrogenase to catalase)].
Topics: Carcinoma; Catalase; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Liver; Oxidoreduc | 1961 |
The relationship between gastric carcinoma and gastric juice lactate (L + D) and lactate dehydrogenase.
Topics: Adult; Aged; Carcinoma; Diagnostic Errors; Female; Gastric Acidity Determination; Gastric Juice; Hum | 1984 |
Hexokinase isoenzymes from anaplastic and differentiated medullary thyroid carcinoma in the rat.
Topics: Adenosine Triphosphate; Animals; Carcinoma; Cell Compartmentation; Glucose; Glucose-6-Phosphate; Glu | 1984 |
Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Caprylates; Ca | 1995 |
Glucose, lactate, and ketone body utilization by human mammary carcinomas in vivo.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Breast Neoplasms; Carcinoma; Female; Glucose; Humans; | 1985 |