Page last updated: 2024-10-17

lactic acid and Carcinoma

lactic acid has been researched along with Carcinoma in 45 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to investigate the potential cardioprotective and anti-cancer effects of carvedilol (CAR) either free or as loaded nano-formulated with or without doxorubicin (DOX) in solid Ehrlich carcinoma (SEC)-bearing mice."8.31Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice. ( Abdin, AA; El Maghraby, GM; El Saadany, AA; Hedya, SE; Zidan, A, 2023)
"HIF-1α is highly expressed in the esophageal carcinoma cell lines tested, and with decreasing levels of oxygen, the expression of HIF-1α and the associated glycolytic enzymes and the extracellular lactic acid concentration were enhanced in the esophageal carcinoma cell lines Eca109 and TE13."7.83Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. ( Feng, YD; Hao, B; He, GJ; Tang, NN; Zeng, L; Zhang, WF; Zhou, HY; Zhu, H, 2016)
"The transferring modified lipid coated PLGA nanoparticles, as a targetable vector, were developed for the targeting delivery of anticancer drugs with paclitaxel (PTX) as a model drug to the ovarian carcinoma, which combines the advantages and avoids disadvantages of polymeric nanoparticles and liposomes in drug delivery."7.80A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles. ( Chen, XG; He, YX; Li, R; Wang, XY; Yang, WY; Yang, X; Zhang, Q, 2014)
"In this study we characterized (3)H-2-deoxy-d-glucose ((3)H -DG) uptake by the estrogen receptor (ER)-positive MCF7 and the ER-negative MDA-MB-231 human breast cancer cell lines and investigated the effect of quercetin (QUE) and epigallocatechin gallate (EGCG) upon (3)H-DG uptake, glucose metabolism and cell viability and proliferation."7.79Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism. ( Araújo, I; Correia-Branco, A; Costa, T; Faria, A; Keating, E; Martel, F; Moreira, L, 2013)
"A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors."5.37Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011)
"The aim of this study was to investigate the potential cardioprotective and anti-cancer effects of carvedilol (CAR) either free or as loaded nano-formulated with or without doxorubicin (DOX) in solid Ehrlich carcinoma (SEC)-bearing mice."4.31Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice. ( Abdin, AA; El Maghraby, GM; El Saadany, AA; Hedya, SE; Zidan, A, 2023)
" Subsequently, we examined the effects of CYC1 on proliferation, glycolysis and chemosensitivity to paclitaxel, which is one of the most common chemotherapeutic agents in breast cancer, in ER-positive breast carcinoma cells (MCF7 and T47D)."3.91Cytochrome c1 as a favorable prognostic marker in estrogen receptor-positive breast carcinoma. ( Hara, M; Ishida, T; Miki, Y; Sasano, H; Sato, A; Suzuki, T; Takagi, K; Yoshimura, A, 2019)
"HIF-1α is highly expressed in the esophageal carcinoma cell lines tested, and with decreasing levels of oxygen, the expression of HIF-1α and the associated glycolytic enzymes and the extracellular lactic acid concentration were enhanced in the esophageal carcinoma cell lines Eca109 and TE13."3.83Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. ( Feng, YD; Hao, B; He, GJ; Tang, NN; Zeng, L; Zhang, WF; Zhou, HY; Zhu, H, 2016)
"The transferring modified lipid coated PLGA nanoparticles, as a targetable vector, were developed for the targeting delivery of anticancer drugs with paclitaxel (PTX) as a model drug to the ovarian carcinoma, which combines the advantages and avoids disadvantages of polymeric nanoparticles and liposomes in drug delivery."3.80A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles. ( Chen, XG; He, YX; Li, R; Wang, XY; Yang, WY; Yang, X; Zhang, Q, 2014)
"In this study we characterized (3)H-2-deoxy-d-glucose ((3)H -DG) uptake by the estrogen receptor (ER)-positive MCF7 and the ER-negative MDA-MB-231 human breast cancer cell lines and investigated the effect of quercetin (QUE) and epigallocatechin gallate (EGCG) upon (3)H-DG uptake, glucose metabolism and cell viability and proliferation."3.79Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism. ( Araújo, I; Correia-Branco, A; Costa, T; Faria, A; Keating, E; Martel, F; Moreira, L, 2013)
"The aim of this work was to prepare paclitaxel-loaded PLGA nanoparticles and determine cytotoxicity of released paclitaxel for two hypoxic human tumor cell lines: breast carcinoma (MCF-7) and carcinoma cervicis (HeLa)."3.75Cytotoxicity of paclitaxel incorporated in PLGA nanoparticles on hypoxic human tumor cells. ( Bai, L; Dou, K; Guo, G; Jin, C; Song, W; Wu, H, 2009)
"MCT4 and Cav-1 are also breast cancer prognostic biomarkers."2.50Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function. ( Lisanti, MP; Martinez-Outschoorn, U; Sotgia, F, 2014)
"TIGAR downregulation in breast carcinoma cells reduces tumor growth."1.91TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer. ( Bartrons, R; Birbe, RC; Caro, J; Domingo-Vidal, M; Győrffy, B; Ko, YH; Lin, Z; Martinez-Outschoorn, U; Philp, NJ; Roche, ME; Tuluc, M; Whitaker-Menezes, D, 2023)
"IP glycerol was only moderately indicative for ischemia after 91-120 minutes with 0,791 ROC AUCs (threshold 122 μmol/l)."1.39Validation of intraluminal and intraperitoneal microdialysis in ischemic small intestine. ( Minkkinen, M; Nordback, I; Perner, A; Pynnönen, L; Räty, S; Sand, J; Tenhunen, J, 2013)
"We have shown earlier that breast cancer cells secrete higher levels of interleukin-6 (IL-6) under hypoxia, leading to the recruitment of hMSCs towards hypoxic tumor cells."1.38Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. ( Ackerstaff, E; Banerjee, D; Glod, JW; Koutcher, JA; Patel, BB; Rattigan, YI; Sukenick, G, 2012)
"A high lactate content in malignant head and neck cancer (Head and neck squamous cell carcinomas, HNSCC) is associated with a higher risk of metastatic spread and lower overall patient survival."1.37Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue. ( Kunkel, M; Mueller-Klieser, W; Reichert, TE; Wagner, W; Walenta, S; Ziebart, T, 2011)
"A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors."1.37Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011)
" Sustained release nanoparticles (NP) offer increased resistance to nuclease degradation, increased amounts of AS uptake, and the possibility of control in dosing and sustained duration of AS administration."1.36Biodistribution of antisense nanoparticles in mammary carcinoma rat model. ( Adwan, H; Berger, MR; Elazar, V; Golomb, G; Lifshitz-Shovali, R; Rohekar, K; Zepp, M, 2010)
"Colon carcinoma is one of the common malignant tumors and has high morbidity and mortality in the world."1.36The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma. ( Cui, FY; Li, SZ; Li, ZY; Mao, YQ; Mu, B; Song, XR; Wei, YQ; Yang, L, 2010)
"The glucose uptake rate of human mammary carcinomas transplanted into nude rats is comparable to values obtained in isotransplanted rodent tumors."1.27Glucose, lactate, and ketone body utilization by human mammary carcinomas in vivo. ( Baessler, KH; Davel, S; Kallinowskil, F; Vaupell, P; Wagner, K, 1985)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19906 (13.33)18.7374
1990's1 (2.22)18.2507
2000's3 (6.67)29.6817
2010's32 (71.11)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Zidan, A1
El Saadany, AA1
El Maghraby, GM1
Abdin, AA1
Hedya, SE1
Roche, ME1
Ko, YH1
Domingo-Vidal, M1
Lin, Z1
Whitaker-Menezes, D1
Birbe, RC1
Tuluc, M1
Győrffy, B1
Caro, J1
Philp, NJ1
Bartrons, R1
Martinez-Outschoorn, U2
Chang, M1
Ellmaker, K1
Esposito, A1
Lauricella, A1
Pa, S1
Roberts, M1
Kurt, RA1
Su, Y1
Yu, QH1
Wang, XY2
Yu, LP1
Wang, ZF1
Cao, YC1
Li, JD1
Zhu, JM1
Quan, XL1
Han, SC1
Fan, XJ1
Li, HM1
Liang, SS1
Chen, X1
Wang, RY1
Ji, XN1
Sato, A1
Takagi, K1
Miki, Y1
Yoshimura, A1
Hara, M1
Ishida, T1
Sasano, H1
Suzuki, T1
Moreira, L1
Araújo, I1
Costa, T1
Correia-Branco, A1
Faria, A1
Martel, F1
Keating, E1
Gottfried, E1
Lang, SA1
Renner, K1
Bosserhoff, A1
Gronwald, W1
Rehli, M1
Einhell, S1
Gedig, I1
Singer, K1
Seilbeck, A1
Mackensen, A1
Grauer, O1
Hau, P1
Dettmer, K1
Andreesen, R1
Oefner, PJ1
Kreutz, M1
Li, X1
Lu, W1
Hu, Y1
Wen, S1
Qian, C1
Wu, W1
Huang, P1
Pynnönen, L1
Minkkinen, M1
Perner, A1
Räty, S1
Nordback, I1
Sand, J1
Tenhunen, J1
Li, R1
Zhang, Q2
Chen, XG1
He, YX1
Yang, WY1
Yang, X1
Xiao, L1
Hu, ZY1
Dong, X1
Tan, Z1
Li, W1
Tang, M1
Chen, L1
Yang, L2
Tao, Y1
Jiang, Y1
Li, J1
Yi, B1
Li, B1
Fan, S1
You, S1
Deng, X1
Hu, F2
Feng, L2
Bode, AM1
Dong, Z1
Sun, LQ1
Cao, Y1
Sotgia, F1
Lisanti, MP1
Punfa, W1
Suzuki, S1
Pitchakarn, P1
Yodkeeree, S1
Naiki, T1
Takahashi, S1
Limtrakul, P1
Demmel, F1
Brischwein, M1
Wolf, P1
Huber, F1
Pfister, C1
Wolf, B1
Giannoni, E1
Taddei, ML1
Morandi, A1
Comito, G1
Calvani, M1
Bianchini, F1
Richichi, B1
Raugei, G1
Wong, N1
Tang, D1
Chiarugi, P1
Bol, GM1
Khan, R1
Heerma van Voss, MR1
Tantravedi, S1
Korz, D1
Kato, Y1
Raman, V1
Sandulache, VC2
Chen, Y1
Skinner, HD1
Lu, T1
Court, LE1
Myers, JN2
Meyn, RE1
Fuller, CD1
Bankson, JA1
Lai, SY1
Pow, EH1
Chen, Z1
Kwong, DL1
Lam, OL1
Zeng, L1
Zhou, HY1
Tang, NN1
Zhang, WF1
He, GJ1
Hao, B1
Feng, YD1
Zhu, H1
Liang, G1
Zhu, Y1
Jing, A1
Wang, J1
Feng, W1
Xiao, Z1
Chen, B1
Dai, Z1
Shestov, AA1
Lai, L1
Locasale, JW1
Gao, J1
Li, L1
Chen, HB1
Li, XQ1
Yan, XZ1
Jin, C1
Bai, L1
Wu, H1
Song, W1
Guo, G1
Dou, K1
Bertuzzi, A1
Fasano, A1
Gandolfi, A1
Sinisgalli, C1
Sabel, MS1
Su, G1
Griffith, KA1
Chang, AE1
Grotius, J1
Dittfeld, C1
Huether, M1
Mueller-Klieser, W2
Baumann, M1
Kunz-Schughart, LA1
Robinson, R1
Bertram, JP1
Reiter, JL1
Lavik, EB1
Ziebart, T1
Walenta, S1
Kunkel, M1
Reichert, TE1
Wagner, W1
Elazar, V1
Adwan, H1
Rohekar, K1
Zepp, M1
Lifshitz-Shovali, R1
Berger, MR1
Golomb, G1
Cui, FY1
Song, XR1
Li, ZY1
Li, SZ1
Mu, B1
Mao, YQ1
Wei, YQ1
De Bari, L1
Chieppa, G1
Marra, E1
Passarella, S1
Hanlon, DJ1
Aldo, PB1
Devine, L1
Alvero, AB1
Engberg, AK1
Edelson, R1
Mor, G1
Ow, TJ1
Pickering, CR1
Frederick, MJ1
Zhou, G1
Fokt, I1
Davis-Malesevich, M1
Priebe, W1
Jeong, YI1
Kim, DH1
Chung, CW1
Yoo, JJ1
Choi, KH1
Kim, CH1
Ha, SH1
Kang, DH1
Hansen, RA1
Anderson, C1
Fettman, MJ1
Larue, SM1
Davenport, DJ1
Gross, KL1
Richardson, KL1
Ogilvie, GK1
Rattigan, YI1
Patel, BB1
Ackerstaff, E1
Sukenick, G1
Koutcher, JA1
Glod, JW1
Banerjee, D1
Terakawa, M1
Tsunoi, Y1
Mitsuhashi, T1
WILSON, HT1
LAZARONI, JA1
MAIER, EC1
BUBANI, V1
CHEN, FW1
Armstrong, CP1
Dent, DM1
Berman, P1
Aitken, RJ1
Rijksen, G1
Oskam, R1
Molthoff, CF1
Lee On, SJ1
Streefkerk, M1
Staal, GE1
Yanai, S1
Okada, H1
Saito, K1
Kuge, Y1
Misaki, M1
Ogawa, Y1
Toguchi, H1
Kallinowskil, F1
Davel, S1
Vaupell, P1
Baessler, KH1
Wagner, K1

Reviews

1 review available for lactic acid and Carcinoma

ArticleYear
Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
    Seminars in oncology, 2014, Volume: 41, Issue:2

    Topics: Animals; Autophagy; Breast Neoplasms; Cachexia; Carcinoma; Caveolin 1; Cell Line, Tumor; Cell Transf

2014

Trials

1 trial available for lactic acid and Carcinoma

ArticleYear
Menhaden oil administration to dogs treated with radiation for nasal tumors demonstrates lower levels of tissue eicosanoids.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:12

    Topics: Animals; Carcinoma; Dietary Fats; Dogs; Double-Blind Method; Eicosanoids; Energy Metabolism; Fish Oi

2011

Other Studies

43 other studies available for lactic acid and Carcinoma

ArticleYear
Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice.
    Toxicology and applied pharmacology, 2023, 04-15, Volume: 465

    Topics: Animals; Carcinoma; Carvedilol; Doxorubicin; Female; Lactic Acid; Liposomes; Mice; Nanoparticles; Va

2023
TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer.
    International journal of cancer, 2023, 11-01, Volume: 153, Issue:9

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Female; Gly

2023
The Impact of Tumor-Associated Macrophages Found at Mammary Carcinoma Sites is Dependent Upon the Tumor Type.
    Immunological investigations, 2023, Volume: 52, Issue:7

    Topics: AMP-Activated Protein Kinases; Carcinoma; Glucose Transporter Type 1; Humans; Lactic Acid; Tumor-Ass

2023
JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression.
    BMC cancer, 2017, Jul-11, Volume: 17, Issue:1

    Topics: Adenosine Triphosphate; Adult; Aged; Biomarkers; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Pr

2017
Establishment of a Model of Microencapsulated SGC7901 Human Gastric Carcinoma Cells Cocultured with Tumor-Associated Macrophages.
    Canadian journal of gastroenterology & hepatology, 2018, Volume: 2018

    Topics: Carcinoma; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Glucose; Humans; Lactic Acid;

2018
Cytochrome c1 as a favorable prognostic marker in estrogen receptor-positive breast carcinoma.
    Histology and histopathology, 2019, Volume: 34, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast; Breast Neoplasms; Carcinoma; Cell Line, T

2019
Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism.
    Experimental cell research, 2013, Jul-15, Volume: 319, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Catechin; Cell Death; Cell Proliferation; Female

2013
New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carcinoma; Cell Line, Tumor;

2013
Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate.
    International journal of oncology, 2013, Volume: 43, Issue:5

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Carcinoma; Cell Cycle; Cell Prolifera

2013
Validation of intraluminal and intraperitoneal microdialysis in ischemic small intestine.
    BMC gastroenterology, 2013, Dec-10, Volume: 13

    Topics: Aged; Carcinoma; Female; Glucose; Glycerol; Humans; Intestine, Small; Ischemia; Lactic Acid; Male; M

2013
A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles.
    Drug research, 2014, Volume: 64, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Chemistry, Pharmaceutical;

2014
Targeting Epstein-Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy.
    Oncogene, 2014, Sep-11, Volume: 33, Issue:37

    Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulatio

2014
Curcumin-loaded PLGA nanoparticles conjugated with anti- P-glycoprotein antibody to overcome multidrug resistance.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:21

    Topics: Animals; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette

2014
Nutrient depletion and metabolic profiles in breast carcinoma cell lines measured with a label-free platform.
    Physiological measurement, 2015, Volume: 36, Issue:7

    Topics: Actins; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Cytocha

2015
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.
    Oncotarget, 2015, Sep-15, Volume: 6, Issue:27

    Topics: Active Transport, Cell Nucleus; Animals; Binding Sites; Carcinoma; Carrier Proteins; Cell Line, Tumo

2015
PLGA nanoparticle formulation of RK-33: an RNA helicase inhibitor against DDX3.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:4

    Topics: Animals; Antineoplastic Agents; Azepines; Breast Neoplasms; Carcinoma; Cell Survival; Delayed-Action

2015
Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:12

    Topics: Animals; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Line, Tu

2015
Salivary Anionic Changes after Radiotherapy for Nasopharyngeal Carcinoma: A 1-Year Prospective Study.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Acetates; Adult; Aged; Anions; Carcinoma; Chlorides; Female; Formates; Humans; Hydrogen-Ion Concentr

2016
Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    World journal of gastroenterology, 2016, May-28, Volume: 22, Issue:20

    Topics: Androstadienes; Carcinoma; Cell Line, Tumor; Esophageal Neoplasms; Gene Expression Regulation, Neopl

2016
Cationic microRNA-delivering nanocarriers for efficient treatment of colon carcinoma in xenograft model.
    Gene therapy, 2016, Volume: 23, Issue:12

    Topics: Animals; Apoptosis; Carcinoma; Colonic Neoplasms; G1 Phase Cell Cycle Checkpoints; Genetic Vectors;

2016
A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.
    Biophysical journal, 2016, Sep-06, Volume: 111, Issue:5

    Topics: Adenosine Triphosphate; Algorithms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferatio

2016
[Metabonomic study of blood plasma in the assessment of liver graft function].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2007, Volume: 29, Issue:6

    Topics: Acetone; Alanine; Biomarkers; Blood Glucose; Carcinoma; Choline; Glutamine; Humans; Lactic Acid; Liv

2007
Cytotoxicity of paclitaxel incorporated in PLGA nanoparticles on hypoxic human tumor cells.
    Pharmaceutical research, 2009, Volume: 26, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma; Cell Hypoxia; Cell Survival

2009
Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?
    Journal of theoretical biology, 2010, Jan-07, Volume: 262, Issue:1

    Topics: Adenosine Triphosphate; Animals; Carcinoma; Dose-Response Relationship, Drug; Energy Metabolism; Fem

2010
Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-alpha in a model of metastatic breast cancer.
    Breast cancer research and treatment, 2010, Volume: 122, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; CD4-Positive T-Lymphocytes; CD8-

2010
Impact of exogenous lactate on survival and radioresponse of carcinoma cells in vitro.
    International journal of radiation biology, 2009, Volume: 85, Issue:11

    Topics: Acidosis; Basigin; Carcinoma; Cell Line, Tumor; Cell Survival; Glucose; HCT116 Cells; HT29 Cells; Hu

2009
New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres.
    Journal of microencapsulation, 2010, Volume: 27, Issue:3

    Topics: Animals; Carcinoma; Cell Line; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Humans; Lactic A

2010
Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:2

    Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Blotting, Western; Carcin

2011
Biodistribution of antisense nanoparticles in mammary carcinoma rat model.
    Drug delivery, 2010, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents; Antisense Elements (Genetics); Bone Neoplasms; Carcinoma; Cell Line,

2010
The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma.
    Oncology reports, 2010, Volume: 24, Issue:3

    Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dependovirus

2010
L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.
    International journal of oncology, 2010, Volume: 37, Issue:6

    Topics: Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; L-Lactate Dehydrogena

2010
Enhanced stimulation of anti-ovarian cancer CD8(+) T cells by dendritic cells loaded with nanoparticle encapsulated tumor antigen.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2011, Volume: 65, Issue:6

    Topics: Antigen Presentation; Antigens, Differentiation; Antigens, Neoplasm; Carcinoma; CD8-Positive T-Lymph

2011
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
    Cancer, 2011, Jul-01, Volume: 117, Issue:13

    Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Prol

2011
Self-assembled nanoparticles of hyaluronic acid/poly(DL-lactide-co-glycolide) block copolymer.
    Colloids and surfaces. B, Biointerfaces, 2012, Feb-01, Volume: 90

    Topics: Antineoplastic Agents; Binding, Competitive; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Delayed

2012
Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment.
    Experimental cell research, 2012, Feb-15, Volume: 318, Issue:4

    Topics: Breast Neoplasms; Carcinoma; Cell Communication; Cell Line, Tumor; Female; Fibroblasts; Glycolysis;

2012
In vitro perforation of human epithelial carcinoma cell with antibody-conjugated biodegradable microspheres illuminated by a single 80 femtosecond near-infrared laser pulse.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Antibodies; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Membrane; Drug Delivery Systems

2012
A test for myocardial infarction; the present status of the use of serum lactic acid dehydrogenase.
    California medicine, 1958, Volume: 88, Issue:5

    Topics: Carcinoma; Clinical Enzyme Tests; Humans; L-Lactate Dehydrogenase; Lactic Acid; Law Enforcement; Myo

1958
[Study of the blood levels of lactic acid in patients with genital carcinoma treated with cobalt 60 teletherapy].
    Annali di ostetricia e ginecologia, 1959, Volume: 81

    Topics: Carcinoma; Cobalt; Cobalt Radioisotopes; Genitalia; Genitalia, Female; Humans; Lactates; Lactic Acid

1959
[Experimental study on the diagnosis of primary carcinoma of the liver. (Ratio of liver homogenate lactic acid dehydrogenase to catalase)].
    [Fukushima igaku zasshi] Fukushima medical journal, 1961, Volume: 11

    Topics: Carcinoma; Catalase; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Liver; Oxidoreduc

1961
The relationship between gastric carcinoma and gastric juice lactate (L + D) and lactate dehydrogenase.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:9

    Topics: Adult; Aged; Carcinoma; Diagnostic Errors; Female; Gastric Acidity Determination; Gastric Juice; Hum

1984
Hexokinase isoenzymes from anaplastic and differentiated medullary thyroid carcinoma in the rat.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:7

    Topics: Adenosine Triphosphate; Animals; Carcinoma; Cell Compartmentation; Glucose; Glucose-6-Phosphate; Glu

1984
Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma.
    Pharmaceutical research, 1995, Volume: 12, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Caprylates; Ca

1995
Glucose, lactate, and ketone body utilization by human mammary carcinomas in vivo.
    Advances in experimental medicine and biology, 1985, Volume: 191

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Breast Neoplasms; Carcinoma; Female; Glucose; Humans;

1985