lactic acid has been researched along with Carbohydrate Metabolism, Inborn Error in 9 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five patients became seizure-free with the onset of ketosis, and anticonvulsants were discontinued." | 1.42 | The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome. ( Bayram, AK; Çağlayan, AO; Canpolat, M; Gumus, H; Kardas, F; Kendirci, M; Kumandas, S; Per, H, 2015) |
| "9 mmol/l, respectively, developed in three patients with hyperosmolar syndromes (two hypernatremic, 417 and 415 mosmol/kg H2O; one hyperglycemic 437 mosmol/kg H2O) during rehydration treatment with 5% fructose in water (fructose dosage 0." | 1.27 | Fructose-induced hyperlactemia in hyperosmolar syndromes. ( Druml, W; Kleinberger, G; Laggner, A; Lenz, K; Schneeweiss, B, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gumus, H | 1 |
| Bayram, AK | 1 |
| Kardas, F | 1 |
| Canpolat, M | 1 |
| Çağlayan, AO | 1 |
| Kumandas, S | 1 |
| Kendirci, M | 1 |
| Per, H | 1 |
| van Baalen, A | 1 |
| Stephani, U | 1 |
| Rohr, A | 1 |
| ISRAELS, S | 1 |
| HAWORTH, JC | 1 |
| GOURLEY, B | 1 |
| FORD, JD | 1 |
| Overweg-Plandsoen, WC | 1 |
| Groener, JE | 1 |
| Wang, D | 2 |
| Onkenhout, W | 1 |
| Brouwer, OF | 1 |
| Bakker, HD | 1 |
| De Vivo, DC | 2 |
| Pascual, JM | 1 |
| Yang, H | 1 |
| Engelstad, K | 1 |
| Jhung, S | 1 |
| Sun, RP | 1 |
| Gudmand-Høyer, E | 1 |
| Krasilnikoff, PA | 1 |
| Skovbjerg, H | 1 |
| Merezhinskaya, N | 1 |
| Fishbein, WN | 1 |
| Davis, JI | 1 |
| Foellmer, JW | 1 |
| Lemonnier, F | 1 |
| Delhotal-Landes, B | 1 |
| Couturier, M | 1 |
| Decimo, D | 1 |
| Odiévre, M | 1 |
| Gautier, M | 1 |
| Lemonnier, A | 1 |
| Druml, W | 1 |
| Kleinberger, G | 1 |
| Lenz, K | 1 |
| Laggner, A | 1 |
| Schneeweiss, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Post Study Continuation of C7 for G1D[NCT02018302] | 0 participants | Expanded Access | No longer available | ||||
| Treatment Development of Triheptanoin for Glucose Transporter Type I Deficiency[NCT02021526] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2015-12-31 | Withdrawn (stopped due to NIH funding resulted in new clinical trial) | ||
| The Glucose Transporter Type I Deficiency (G1D) Registry[NCT02013583] | 750 participants (Anticipated) | Observational [Patient Registry] | 2013-12-31 | Recruiting | |||
| Clinical Trial of Citric Acid Cycle Stimulation in Energy-deficiency States: Treatment Development for Glucose Transporter Type I Deficiency Syndrome (G1D) (NMTUT 2010B)[NCT02018315] | Phase 1 | 14 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Magnetic Resonance Imaging (MRI) used to calculate brain metabolic rate. Brain metabolic rate compared before oil ingestion (Baseline), 90 minutes after oil ingestion, and after 3 months of daily oil ingestion in each participant. Triheptanoin metabolism may lead to increased oxygen consumption only while the brain undergoes a reduction of ictogenesis. We hypothesize that when ictogenesis is abolished by triheptanoin or absent at baseline, triheptanoin exerts little or no effect on CMR02. (NCT02018315)
Timeframe: 3 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Experimental: Triheptanoin | 5 |
Visual analysis of EEG recording to determine the fraction of spike-range within the area of recording. (NCT02018315)
Timeframe: 1 day
| Intervention | Participants (Count of Participants) |
|---|---|
| Experimental: Triheptanoin | 13 |
1 review available for lactic acid and Carbohydrate Metabolism, Inborn Error
| Article | Year |
|---|---|
Sucrose-isomaltose malabsorption.
Topics: Animals; Barium; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Disaccharidases; Disaccharide | 1984 |
2 trials available for lactic acid and Carbohydrate Metabolism, Inborn Error
| Article | Year |
|---|---|
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects.
Topics: 3-O-Methylglucose; Adolescent; Blood Glucose; Brain; Carbohydrate Metabolism, Inborn Errors; Child; | 2005 |
Mutations in MCT1 cDNA in patients with symptomatic deficiency in lactate transport.
Topics: Adult; Arm; Biological Transport, Active; Carbohydrate Metabolism, Inborn Errors; Carrier Proteins; | 2000 |
6 other studies available for lactic acid and Carbohydrate Metabolism, Inborn Error
| Article | Year |
|---|---|
The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome.
Topics: Adolescent; Biomarkers; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Child, Prescho | 2015 |
Increased brain lactate during stroke-like episode in a patient with congenital disorder of glycosylation type Ia.
Topics: Acidosis, Lactic; Aspartic Acid; Brain; Carbohydrate Metabolism, Inborn Errors; Child; Female; Fever | 2009 |
CHRONIC ACIDOSIS DUE TO AN ERROR IN LACTATE AND PYRUVATE METABOLISM. REPORT OF TWO CASES.
Topics: Acetoacetates; Acidosis; Blood; Blood Gas Analysis; Carbohydrate Metabolism; Carbohydrate Metabolism | 1964 |
GLUT-1 deficiency without epilepsy--an exceptional case.
Topics: Ataxia; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; DNA; DNA Mutational Analysis; | 2003 |
Comparative use of glucose and fructose in cultured fibroblasts from patients with hereditary fructose intolerance.
Topics: Carbohydrate Metabolism, Inborn Errors; Cells, Cultured; Child; Child, Preschool; Female; Fibroblast | 1987 |
Fructose-induced hyperlactemia in hyperosmolar syndromes.
Topics: Acidosis; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetic Coma; Electrolytes; Female | 1986 |