Page last updated: 2024-10-17

lactic acid and Cachexia

lactic acid has been researched along with Cachexia in 19 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.

Research Excerpts

ExcerptRelevanceReference
"In this study, we investigated the effect of capsaicin treatment on tumor growth and the metabolic indicators of cachexia in Walker 256 tumor-bearing rats."7.91Nutrition and Cancercapsaicin Treatment Reduces Tumor Growth, Tumor Cell Proliferation Ex Vivo and Partially Reverses Cancer Cachexia in Walker 256 Tumor-Bearing Rats. ( Claudio Fernandes, L; Messias-Reason, IJ; Naliwaiko, K; Ricardo de Brito Bello, S; Rossetti, FX; Vicentini, MS, 2019)
"In this study, we investigated the effect of capsaicin treatment on tumor growth and the metabolic indicators of cachexia in Walker 256 tumor-bearing rats."3.91Nutrition and Cancercapsaicin Treatment Reduces Tumor Growth, Tumor Cell Proliferation Ex Vivo and Partially Reverses Cancer Cachexia in Walker 256 Tumor-Bearing Rats. ( Claudio Fernandes, L; Messias-Reason, IJ; Naliwaiko, K; Ricardo de Brito Bello, S; Rossetti, FX; Vicentini, MS, 2019)
" After 12 days of treatment, the tumor growth, some parameters of cachexia/anorexia, the blood levels of triacylglycerol, glucose, lactate and urea, the peripheral response to insulin and the hepatic glycolysis and gluconeogenesis were investigated."3.79Effect of infliximab on metabolic disorders induced by Walker-256 tumor in rats. ( Bazotte, RB; Borba-Murad, GR; da Rocha, AF; de Morais, H; de Souza, CO; de Souza, HM; Miksza, DR, 2013)
"We investigated the effect of chronic supplementation with shark liver oil (SLO), an antitumor supplement source of n-3 fatty acids and 1-O-alkylglycerols, alone and combined with coconut fat (CF), a source of saturated fatty acids, on Walker 256 tumor growth and cachexia."3.77Chronic supplementation with shark liver oil for reducing tumor growth and cachexia in walker 256 tumor-bearing rats. ( de Brito Belo, SR; de Brito, GA; Fernandes, LC; Franzói, AM; Iagher, F; Muehlmann, LA; Muritiba, AL; Naliwaiko, K; Steffani, JA; Yamazaki, RK, 2011)
" At 14 days after tumor implantation, rats not supplemented displayed cancer cachexia characterized by loss of body weight, hypoglycemia, hyperlacticidemia, hypertriglyceridemia, decreased food intake and depletion of glycogen stores in the liver and skeletal muscles."3.74Effect of fish oil supplementation for 2 generations on changes in macrophage function induced by Walker 256 cancer cachexia in rats. ( Aikawa, J; Bonatto, SJ; Curi, R; Fernandes, LC; Folador, A; Hirabara, SM; Yamazaki, RK, 2007)
"MCT4 and Cav-1 are also breast cancer prognostic biomarkers."2.50Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function. ( Lisanti, MP; Martinez-Outschoorn, U; Sotgia, F, 2014)
"Cardiac cachexia was provoked in male rats by the ligation of the left coronary artery."1.40Mitochondrial protein synthesis is increased in oxidative skeletal muscles of rats with cardiac cachexia. ( Azarnoush, K; Boirie, Y; Cano, N; Chanséaume, S; Giraudet, C; Guillet, C; Lusson, JR; Patrac, V; Thibault, R; Walrand, S, 2014)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's2 (10.53)18.2507
2000's7 (36.84)29.6817
2010's7 (36.84)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Barayan, D1
Abdullahi, A1
Knuth, CM1
Khalaf, F1
Rehou, S1
Screaton, RA1
Jeschke, MG1
Ricardo de Brito Bello, S1
Naliwaiko, K2
Vicentini, MS1
Rossetti, FX1
Claudio Fernandes, L1
Messias-Reason, IJ1
Szabó, T1
Postrach, E1
Mähler, A1
Kung, T1
Turhan, G1
von Haehling, S1
Anker, SD1
Boschmann, M1
Doehner, W1
Miksza, DR1
de Souza, CO1
de Morais, H1
da Rocha, AF1
Borba-Murad, GR2
Bazotte, RB2
de Souza, HM2
Thibault, R1
Chanséaume, S1
Azarnoush, K1
Guillet, C1
Giraudet, C1
Patrac, V1
Lusson, JR1
Cano, N1
Boirie, Y1
Walrand, S1
Martinez-Outschoorn, U1
Sotgia, F1
Lisanti, MP1
Iagher, F1
de Brito Belo, SR1
Franzói, AM1
de Brito, GA1
Yamazaki, RK3
Muritiba, AL1
Muehlmann, LA1
Steffani, JA1
Fernandes, LC3
Cassolla, P1
Moreira, CC1
Liboni, TF1
Zaia, CT1
Meijsing, B1
Carbó, N2
López-Soriano, FJ2
Argilés, JM2
Togni, V1
Ota, CC1
Folador, A2
Júnior, OT1
Aikawa, J2
Freitas, FA1
Longo, R1
Martins, EF1
Calder, PC1
Curi, R2
Bongaerts, GP1
van Halteren, HK1
Verhagen, CA1
Wagener, DJ1
Hirabara, SM1
Bonatto, SJ1
de Sá-Nakanishi, AB1
Bracht, F1
Yamamoto, NS1
Padilha, F1
Kelmer-Bracht, AM1
Bracht, A1
Conlon, KC1
Bading, JR1
McDermott, EW1
Corbally, MT1
Tolvo, AJ1
Brennan, MF1
Eliaz, R1
Wallach, D1
Kost, J1
Ogilvie, GK1
Fettman, MJ1
Mallinckrodt, CH1
Walton, JA1
Hansen, RA1
Davenport, DJ1
Gross, KL1
Richardson, KL1
Rogers, Q1
Hand, MS1
Busquets, S1
Alvarez, B1
van Royen, M1
Inculet, RI1
Peacock, JL1
Gorschboth, CM1
Norton, JA1
Tisdale, MJ1
Brennan, RA1

Reviews

1 review available for lactic acid and Cachexia

ArticleYear
Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
    Seminars in oncology, 2014, Volume: 41, Issue:2

    Topics: Animals; Autophagy; Breast Neoplasms; Cachexia; Carcinoma; Caveolin 1; Cell Line, Tumor; Cell Transf

2014

Trials

1 trial available for lactic acid and Cachexia

ArticleYear
Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized placebo-controlled study.
    Cancer, 2000, Apr-15, Volume: 88, Issue:8

    Topics: Animals; Antineoplastic Agents; Arginine; Cachexia; Diet; Dietary Supplements; Disease Models, Anima

2000

Other Studies

17 other studies available for lactic acid and Cachexia

ArticleYear
Lactate shuttling drives the browning of white adipose tissue after burn.
    American journal of physiology. Endocrinology and metabolism, 2023, 09-01, Volume: 325, Issue:3

    Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Biological Transport; Burns; Cachexia; Humans

2023
Nutrition and Cancercapsaicin Treatment Reduces Tumor Growth, Tumor Cell Proliferation Ex Vivo and Partially Reverses Cancer Cachexia in Walker 256 Tumor-Bearing Rats.
    Nutrition and cancer, 2019, Volume: 71, Issue:1

    Topics: Animals; Cachexia; Capsaicin; Carcinoma 256, Walker; Cell Proliferation; Lactic Acid; Male; Rats; Ra

2019
Increased catabolic activity in adipose tissue of patients with chronic heart failure.
    European journal of heart failure, 2013, Volume: 15, Issue:10

    Topics: Adipose Tissue; Adult; Aged; Atrial Natriuretic Factor; Blood Glucose; Cachexia; Case-Control Studie

2013
Effect of infliximab on metabolic disorders induced by Walker-256 tumor in rats.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Blood Glucose; Cachexia; C

2013
Mitochondrial protein synthesis is increased in oxidative skeletal muscles of rats with cardiac cachexia.
    Nutrition research (New York, N.Y.), 2014, Volume: 34, Issue:3

    Topics: Amino Acids; Animals; Blood Glucose; Body Weight; Cachexia; Citrate (si)-Synthase; Echocardiography;

2014
Chronic supplementation with shark liver oil for reducing tumor growth and cachexia in walker 256 tumor-bearing rats.
    Nutrition and cancer, 2011, Volume: 63, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Bod

2011
Changes in blood metabolic parameters during the development of Walker-256 tumour-induced cachexia in rats are not caused by decreased food intake.
    Cell biochemistry and function, 2012, Volume: 30, Issue:4

    Topics: Animals; Anorexia; Cachexia; Carcinoma 256, Walker; Cholesterol; Fatty Acids, Nonesterified; Glycero

2012
Effects of the phosphodiesterase-IV inhibitor EMD 95832/3 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma.
    Cancer letters, 2002, Dec-15, Volume: 188, Issue:1-2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Alanine; Animals; Blood Glucose; Cachexia; Cell

2002
Cancer cachexia and tumor growth reduction in Walker 256 tumor-bearing rats supplemented with N-3 polyunsaturated fatty acids for one generation.
    Nutrition and cancer, 2003, Volume: 46, Issue:1

    Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cachexia; Carcinoma 256, Walker; Dietary

2003
Cancer cachexia demonstrates the energetic impact of gluconeogenesis in human metabolism.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Adenosine Triphosphate; Cachexia; Energy Metabolism; Gluconeogenesis; Humans; Hydrogen-Ion Concentra

2006
Effect of fish oil supplementation for 2 generations on changes in macrophage function induced by Walker 256 cancer cachexia in rats.
    International journal of cancer, 2007, Jan-15, Volume: 120, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Cachexia; Carcinoma 256, Walker; Coconut Oil; Eating; Fatty Aci

2007
The action of extracellular NAD+ in the liver of healthy and tumor-bearing rats: model analysis of the tumor-induced modified response.
    Experimental and molecular pathology, 2008, Volume: 84, Issue:3

    Topics: Animals; Cachexia; Carcinoma 256, Walker; Eicosanoids; Extracellular Fluid; Glucose; Hemodynamics; I

2008
Extremity metabolism in the cachectic, VX-2 carcinoma-bearing rabbit.
    The Journal of surgical research, 1993, Volume: 55, Issue:3

    Topics: Amino Acids; Animals; Blood Glucose; Cachexia; Calcium; Eating; Extremities; Glucagon; Hematopoiesis

1993
Long-term protection against the effects of tumour necrosis factor by controlled delivery of the soluble p55 TNF receptor.
    Cytokine, 1996, Volume: 8, Issue:6

    Topics: Animals; Antigens, CD; Arthritis; Biocompatible Materials; Cachexia; Delayed-Action Preparations; Hu

1996
Lack of effect of the cytokine suppressive agent FR167653 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma.
    Cancer letters, 2000, Aug-31, Volume: 157, Issue:1

    Topics: Adipose Tissue; Alanine; Animals; Anorexia; Blood Glucose; Cachexia; Cell Division; Female; Interleu

2000
Gluconeogenesis in the tumor-influenced rat hepatocyte: importance of tumor burden, lactate, insulin, and glucagon.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:5

    Topics: Amino Acids; Animals; Blood Glucose; Cachexia; Eating; Glucagon; Gluconeogenesis; Insulin; Lactates;

1987
Metabolic substrate utilization by a tumour cell line which induces cachexia in vivo.
    British journal of cancer, 1986, Volume: 54, Issue:4

    Topics: Adenocarcinoma; Animals; Cachexia; Cell Line; Colonic Neoplasms; Glucose; Ketone Bodies; Lactates; L

1986