lactic acid has been researched along with Brain Vascular Disorders in 33 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of a unique combination of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like syndrome (MELAS) with acanthocytosis is reported." | 7.67 | Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes with acanthocytosis: a clinicopathological study of a unique case. ( Kazui, H; Mukoyama, M; Nonaka, I; Satoyoshi, E; Sunohara, N; Yoshida, M, 1986) |
| " In the investigation it was found: lactic acidosis; stroke like episodes and calcification in the basal ganglia on computerized axial tomography; ragged red fibers on muscle biopsy and decreased of cytochrome C oxidase in the muscle tissue." | 7.67 | [MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case]. ( Abdalla, H; Lohr, A; Werneck, LC, 1987) |
| "In contrast, all vehicle-treated heatstroke animals had lower levels of MAP, cerebral perfusion pressure, cerebral blood flow, and brain partial pressure of oxygen." | 5.35 | L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke. ( Chen, YC; Huang, CI; Lee, CH; Lin, MT; Liu, YC; Wang, LM; Yen, DH, 2008) |
| "This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE)." | 3.71 | Determination of lactic acid level in systemic liquids in children with progressive encephalopathies. ( Bielińska-Bujniewicz, E; Emich-Widera, E; Marszał, E; Pietruszewski, J; Wojaczyńska-Stanek, K, 2002) |
| "To our knowledge, this is the first study to assess the response to treatment of a MELAS strokelike episode and the first to show an increase in the lactate-creatine ratio in a brain region that was associated with a clinical abnormality, even though it appeared normal on magnetic resonance imaging." | 3.70 | Magnetic resonance spectroscopy: use in monitoring MELAS treatment. ( Kaplan, GP; Kingsley, PB; Lustbader, D; O'Shea, M; Pavlakis, SG; Stacpoole, PW, 1998) |
| "A case of a unique combination of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like syndrome (MELAS) with acanthocytosis is reported." | 3.67 | Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes with acanthocytosis: a clinicopathological study of a unique case. ( Kazui, H; Mukoyama, M; Nonaka, I; Satoyoshi, E; Sunohara, N; Yoshida, M, 1986) |
| " In the investigation it was found: lactic acidosis; stroke like episodes and calcification in the basal ganglia on computerized axial tomography; ragged red fibers on muscle biopsy and decreased of cytochrome C oxidase in the muscle tissue." | 3.67 | [MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case]. ( Abdalla, H; Lohr, A; Werneck, LC, 1987) |
| "Preoperative MRI examinations showed periventricular leukomalacia (PVL) in 4 patients (16%) and infarct in 2 subjects (8%)." | 2.70 | An MRI study of neurological injury before and after congenital heart surgery. ( Chiavacci, RM; Clancy, RR; Galli, KK; Gaynor, JW; Kurth, CD; Mahle, WT; Montenegro, LM; Nicolson, SC; Spray, TL; Tavani, F; Wernovsky, G; Zimmerman, RA, 2002) |
| "OBJECTIVE Delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH) is one of the major contributors to poor outcome." | 1.48 | Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage. ( Enblad, P; Engquist, H; Hillered, L; Howells, T; Johnson, U; Lewén, A; Nilsson, P; Ronne-Engström, E; Rostami, E, 2018) |
| "In this study, we used a global cerebral ischemia induced by four-vessel occlusion as an established animal model for ischemic stroke to investigate metabolic changes after 24 h reperfusion, when transitions occur due to the onset of delayed neuronal death." | 1.48 | NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia. ( Baranovicova, E; Cierny, D; Grendar, M; Kalenska, D; Lehotsky, J; Tomascova, A, 2018) |
| "In contrast, all vehicle-treated heatstroke animals had lower levels of MAP, cerebral perfusion pressure, cerebral blood flow, and brain partial pressure of oxygen." | 1.35 | L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke. ( Chen, YC; Huang, CI; Lee, CH; Lin, MT; Liu, YC; Wang, LM; Yen, DH, 2008) |
| "In multiple sclerosis, myelopathy, stroke, epilepsy and viral meningitis glutamate, hypoxanthine, xanthine, and uric acid are increased 2-3-fold compared to controls." | 1.30 | Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. ( Kempski, OS; Lowitzsch, K; Stover, JF, 1997) |
| "Lactic acid concentration has been determined in the cerebrospinal fluid (CSF) of 715 patients suffering from various neurological diseases." | 1.27 | [Importance of cerebrospinal fluid lactate determination in neurological diseases]. ( Busse, O; Hornig, CR; Kaps, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (36.36) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 5 (15.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rostami, E | 1 |
| Engquist, H | 1 |
| Howells, T | 1 |
| Johnson, U | 1 |
| Ronne-Engström, E | 1 |
| Nilsson, P | 1 |
| Hillered, L | 1 |
| Lewén, A | 1 |
| Enblad, P | 1 |
| Baranovicova, E | 1 |
| Grendar, M | 1 |
| Kalenska, D | 1 |
| Tomascova, A | 1 |
| Cierny, D | 1 |
| Lehotsky, J | 1 |
| Lim, CC | 1 |
| Gan, R | 1 |
| Chan, CL | 1 |
| Tan, AW | 1 |
| Khoo, JJ | 1 |
| Chia, SY | 1 |
| Kao, SL | 1 |
| Abisheganaden, J | 1 |
| Sitoh, YY | 1 |
| Ozatik, MA | 1 |
| Kocabeyoglu, S | 1 |
| Küçüker, SA | 1 |
| Saritas, A | 1 |
| Altintas, G | 1 |
| Kervan, U | 1 |
| Yavas, S | 1 |
| Paç, M | 1 |
| Bockeria, LA | 1 |
| Malashenkov, AI | 1 |
| Rychin, SV | 1 |
| Walther, T | 1 |
| Dhein, S | 1 |
| Ullmann, C | 1 |
| Schneider, K | 1 |
| Bilz, T | 1 |
| Rastan, A | 1 |
| Garbade, J | 1 |
| Falk, V | 1 |
| Emrich, FC | 1 |
| Muth, P | 1 |
| Mohr, FW | 1 |
| Kostelka, M | 1 |
| Mahle, WT | 1 |
| Tavani, F | 1 |
| Zimmerman, RA | 1 |
| Nicolson, SC | 1 |
| Galli, KK | 1 |
| Gaynor, JW | 1 |
| Clancy, RR | 1 |
| Montenegro, LM | 1 |
| Spray, TL | 1 |
| Chiavacci, RM | 1 |
| Wernovsky, G | 1 |
| Kurth, CD | 1 |
| Chen, YC | 1 |
| Liu, YC | 1 |
| Yen, DH | 1 |
| Wang, LM | 1 |
| Huang, CI | 1 |
| Lee, CH | 1 |
| Lin, MT | 1 |
| Siesjö, BK | 1 |
| Gelmers, HJ | 1 |
| Ishchenko, MM | 1 |
| Dorogiĭ, AN | 1 |
| Shkrobot, SI | 1 |
| Hornig, CR | 1 |
| Busse, O | 1 |
| Kaps, M | 1 |
| Mathews, VP | 1 |
| Barker, PB | 1 |
| Blackband, SJ | 1 |
| Chatham, JC | 1 |
| Bryan, RN | 1 |
| Blamire, AM | 1 |
| Graham, GD | 2 |
| Rothman, DL | 2 |
| Prichard, JW | 2 |
| Hetherington, HP | 1 |
| Pan, JW | 1 |
| Mason, GF | 1 |
| Ponder, SL | 1 |
| Twieg, DB | 1 |
| Deutsch, G | 1 |
| Mountz, J | 1 |
| Pohost, GM | 1 |
| Lockette, W | 1 |
| Kirkland, K | 1 |
| Farrow, S | 1 |
| Sperl, W | 1 |
| Felber, S | 1 |
| Skladal, D | 1 |
| Wermuth, B | 1 |
| Stover, JF | 1 |
| Lowitzsch, K | 1 |
| Kempski, OS | 1 |
| Pavlakis, SG | 1 |
| Kingsley, PB | 1 |
| Kaplan, GP | 1 |
| Stacpoole, PW | 1 |
| O'Shea, M | 1 |
| Lustbader, D | 1 |
| Wild, JM | 1 |
| Marshall, I | 1 |
| Kmiecik, JA | 1 |
| Gregory, CD | 1 |
| Liang, ZP | 1 |
| Lauterbur, PC | 1 |
| Dawson, MJ | 1 |
| Marszał, E | 1 |
| Wojaczyńska-Stanek, K | 1 |
| Pietruszewski, J | 1 |
| Emich-Widera, E | 1 |
| Bielińska-Bujniewicz, E | 1 |
| Howseman, AM | 1 |
| Petroff, OA | 1 |
| Lantos, G | 1 |
| Fayad, PB | 1 |
| Brass, LM | 1 |
| Shulman, GI | 1 |
| Shulman, RG | 1 |
| Gabrielian, ES | 1 |
| Akopov, SE | 1 |
| Grigorian, MR | 1 |
| Tumasian, KS | 1 |
| Abe, K | 1 |
| Fujimura, H | 1 |
| Nishikawa, Y | 1 |
| Yorifuji, S | 1 |
| Mezaki, T | 1 |
| Hirono, N | 1 |
| Nishitani, N | 1 |
| Kameyama, M | 1 |
| Mukoyama, M | 1 |
| Kazui, H | 1 |
| Sunohara, N | 1 |
| Yoshida, M | 1 |
| Nonaka, I | 2 |
| Satoyoshi, E | 1 |
| Mizuno, Y | 1 |
| Ishiguro, K | 1 |
| Okamoto, K | 1 |
| Morimatsu, M | 1 |
| Hirai, S | 1 |
| Werneck, LC | 1 |
| Abdalla, H | 1 |
| Lohr, A | 1 |
| Palmer, GC | 1 |
| Kobayashi, M | 1 |
| Morishita, H | 1 |
| Sugiyama, N | 1 |
| Yokochi, K | 1 |
| Nakano, M | 1 |
| Wada, Y | 1 |
| Hotta, Y | 1 |
| Terauchi, A | 1 |
| Mechír, E | 1 |
| Mechírová, E | 1 |
| Barsan, WG | 1 |
| Hedges, JR | 1 |
| Syverud, SA | 1 |
| Dronen, SC | 1 |
| Dimlich, RV | 1 |
| Dzudza, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779] | 12 participants (Actual) | Observational | 2017-08-28 | Completed | |||
| Cerebral Anatomy, Hemodynamics and Metabolism In Single Ventricles: Relationship to Neurodevelopment[NCT02919956] | 119 participants (Actual) | Observational | 2016-04-30 | Active, not recruiting | |||
| International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery[NCT05673499] | 900 participants (Anticipated) | Observational | 2022-08-12 | Recruiting | |||
| Autologous Cord Blood Cells for Patients With HLHS: Phase I Study of Feasibility and Safety[NCT01445041] | Phase 1 | 7 participants (Actual) | Interventional | 2011-09-01 | Terminated (stopped due to Funding Period Ended) | ||
| Phase 3 Trial of Coenzyme Q10 in Mitochondrial Disease[NCT00432744] | Phase 3 | 24 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The McMaster Gross Motor Function is a validated scale ranging from 0 to 100 (the higher the better). Since there was the possibility of a subject becoming totally disabled our FDA peer reviewed design called for its use as follows: If the subject completed both periods, the score was calculated as the difference in scores between the end of Period 2 (at 12 months) minus that at the end of Period 1 (6 months). If a subject became totally disabled, this difference was considered as plus infinity if it occurred in period 1 (Penalizes period 1), and minus infinity if it occurred in Period 2 (Penalizes period 2). The two treatments were compared via the Wilcoxon test, and the effect size was estimated using Kendall's Tau-B. This is interpreted in a similar manner to correlation with positive values favoring COQenzyme10 and negative values favoring placebo. One of the links in this report is to the the GMFM scale and how it is scored. A link to the instrument is included. (NCT00432744)
Timeframe: Taken at 6 and 12 Months
| Intervention | units on a scale (Median) |
|---|---|
| Placebo First | -0.002 |
| CoenzymeQ10 Frist | -0.12 |
This is a multivariate analysis of the first two outcomes: Period 2 minus Period 1 GMFM88 and Peds Quality of Life, analyzed as follows: First, to be in the analysis, subjects must contribute at least one of these endpoints. Second, if the subject became totally disabled during period 1, the difference was defined as + infinity, (highest possible evidence favoring period 2), and if the subject became totally disabled in period 2, the subject was scored as - infinity (highest possible evidence favoring period 1). Period 2 minus period 1 differences were ranked form low to high with missing values scores at the mid-rank. The Hotelling T-square was computed on these ranks and the P-value was obtained from 100,000 rerandomizations as the fraction of rerandomizations with T-sq at least as large as that observed. (NCT00432744)
Timeframe: end of 12 month minus end of 6 month difference.
| Intervention | participants (Number) |
|---|---|
| Placebo First | 7 |
| CoenzymeQ10 Frist | 8 |
"The Pediatric Quality of Life Scale is a validated scale ranging from 0 to 100 (the higher the better). Since there was the possibility of a subject becoming totally disabled our FDA peer reviewed design called for its use as follows: If the subject completed both periods, the score was calculated as the difference in scores between the end of Period 2 (at 12 months) minus that at the end of Period 1 (6 months). If a subject became totally disabled, this difference was considered as plus infinity if it occurred in period 1 (Penalizes period 1), and minus infinity if it occurred in Period 2 (Penalizes period 2). The two treatments were compared via the Wilcoxon test, and the effect size was estimated using Kendall's Tau-B. This is interpreted in a similar manner to correlation with positive values favoring COQenzyme10 and negative values favoring placebo. Goggle pedsQL and Mapi to browse the copyrighted manual. A link to the instrument is included." (NCT00432744)
Timeframe: At 6 and 12 Months
| Intervention | units on a scale (Median) |
|---|---|
| Placebo First | -1.1 |
| CoenzymeQ10 Frist | -11.9 |
3 reviews available for lactic acid and Brain Vascular Disorders
| Article | Year |
|---|---|
Cell damage in the brain: a speculative synthesis.
Topics: Acidosis; Animals; Biological Transport, Active; Brain Ischemia; Calcium; Cell Membrane; Cerebrovasc | 1981 |
The neurology of hypertension, a neurologist view.
Topics: Adult; Blood-Brain Barrier; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; | 1982 |
Cyclic nucleotides in stroke and related cerebrovascular disorders.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adenylyl Cyclas | 1985 |
1 trial available for lactic acid and Brain Vascular Disorders
| Article | Year |
|---|---|
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
29 other studies available for lactic acid and Brain Vascular Disorders
| Article | Year |
|---|---|
Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Cerebr | 2018 |
NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia.
Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine | 2018 |
Severe hypoglycemia associated with an illegal sexual enhancement product adulterated with glibenclamide: MR imaging findings.
Topics: Adult; Aged; Blood Volume; Brain; Cerebrovascular Disorders; Coma; Consciousness Disorders; Diffusio | 2009 |
Neurochemical markers during selective cerebral perfusion via the right brachial artery.
Topics: Adult; Aged; Aorta, Thoracic; Aortic Diseases; Biomarkers; Blood Glucose; Brachial Artery; Cardiopul | 2010 |
eComment: Re: Neurochemical markers during selective cerebral perfusion via the right brachial artery.
Topics: Aorta, Thoracic; Aortic Diseases; Biomarkers; Blood Glucose; Brachial Artery; Cardiopulmonary Bypass | 2010 |
Cerebral protection during controlled hypoperfusion in a piglet model: comparison of moderate (25°C) versus deep (18°C) hypothermia at various flow rates using intraoperative measurements and ex vivo investigation.
Topics: Animals; Animals, Newborn; Biomarkers; Cardiopulmonary Bypass; Cerebrovascular Circulation; Cerebrov | 2013 |
L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke.
Topics: Animals; Arginine; Cerebrovascular Circulation; Cerebrovascular Disorders; Cytokines; Encephalitis; | 2008 |
[Lactic and pyruvic acid levels and lactate dehydrogenase activity in the blood in stroke].
Topics: Adult; Aged; Cerebrovascular Disorders; Female; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Ac | 1984 |
[Importance of cerebrospinal fluid lactate determination in neurological diseases].
Topics: Central Nervous System Diseases; Cerebrovascular Disorders; Diagnosis, Differential; Encephalitis; E | 1983 |
Cerebral metabolites in patients with acute and subacute strokes: concentrations determined by quantitative proton MR spectroscopy.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebrovascular Dis | 1995 |
Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cerebrovascular Disorders; Choline; Creatin | 1994 |
2D 1H spectroscopic imaging of the human brain at 4.1 T.
Topics: Brain; Cerebrovascular Disorders; Humans; Image Processing, Computer-Assisted; Lactates; Lactic Acid | 1994 |
Alpha 2-adrenergic agonists increase cellular lactate efflux.
Topics: Adrenergic alpha-Agonists; Animals; Body Temperature Regulation; Cells, Cultured; Cerebrovascular Di | 1996 |
Metabolic stroke in carbamyl phosphate synthetase deficiency.
Topics: Ammonia; Brain Damage, Chronic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cerebrovascula | 1997 |
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pr | 1997 |
Magnetic resonance spectroscopy: use in monitoring MELAS treatment.
Topics: Adult; Brain; Cerebrovascular Disorders; Creatine; Dichloroacetic Acid; Female; Humans; Lactic Acid; | 1998 |
In vivo lactate editing in single voxel proton spectroscopy and proton spectroscopic imaging by homonuclear polarisation transfer.
Topics: Brain; Cerebrovascular Disorders; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Phantoms, Im | 1999 |
Lactate quantitation in a gerbil brain stroke model by GSLIM of multiple-quantum-filtered signals. Generalized spectral localization by imaging.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Disorders; Disease Models, Animal; Filtration; Gerbi | 1999 |
Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.
Topics: Adolescent; Brain Diseases; Case-Control Studies; Cerebrovascular Disorders; Child; Child, Preschool | 2002 |
Localized proton NMR observation of [3-13C]lactate in stroke after [1-13C]glucose infusion.
Topics: Blood Glucose; Carbon Isotopes; Cerebrovascular Disorders; Feasibility Studies; Glucose; Humans; Inf | 1991 |
[Cerebrovascular damage caused by platelet and leukocyte activation and treatment with neurotroponin].
Topics: Animals; Brain; Cats; Cell Aggregation; Cerebrovascular Disorders; Lactates; Lactic Acid; Leukocytes | 1991 |
Marked reduction in CSF lactate and pyruvate levels after CoQ therapy in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS).
Topics: Acidosis, Lactic; Adult; Agnosia; Cerebrovascular Disorders; Delirium; Dose-Response Relationship, D | 1991 |
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes with acanthocytosis: a clinicopathological study of a unique case.
Topics: Acanthocytes; Acidosis; Adult; Aphasia; Atrophy; Biopsy; Cerebellum; Cerebral Cortex; Cerebral Ventr | 1986 |
[A case of mitochondrial encephalomyopathy characterized by repeated stroke-like episodes].
Topics: Adult; Brain Diseases; Cerebrovascular Disorders; Electroencephalography; Epilepsies, Myoclonic; Hum | 1989 |
[MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case].
Topics: Acidosis, Lactic; Brain Diseases; Cerebrovascular Disorders; Child; Electron Transport Complex IV; H | 1987 |
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome and NADH-CoQ reductase deficiency.
Topics: Acidosis; Adolescent; Cerebrovascular Disorders; Child, Preschool; Humans; Intellectual Disability; | 1986 |
[Changes in lactate, pyruvate and the lactate/pyruvate quotient in cerebrospinal fluid in ischemic cerebrovascular accidents].
Topics: Adult; Aged; Cerebrovascular Disorders; Humans; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruv | 1988 |
Effects of dichloroacetate in spinal stroke in the rabbit.
Topics: Acetates; Animals; Blood Glucose; Cerebrovascular Disorders; Dichloroacetic Acid; Lactates; Lactic A | 1987 |
The biochemical complex of ischemic damage to the central nervous system.
Topics: Bicarbonates; Carbon Dioxide; Catecholamines; Cerebrovascular Disorders; Humans; Hydrogen-Ion Concen | 1985 |