Page last updated: 2024-10-17

lactic acid and Brain Disorders

lactic acid has been researched along with Brain Disorders in 89 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" In the investigation it was found: lactic acidosis; stroke like episodes and calcification in the basal ganglia on computerized axial tomography; ragged red fibers on muscle biopsy and decreased of cytochrome C oxidase in the muscle tissue."7.67[MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case]. ( Abdalla, H; Lohr, A; Werneck, LC, 1987)
"Pyruvate dehydrogenase complex (PDHC) activity was measured in cultured fibroblasts from 12 patients with Friedreich's ataxia (FA), and in 1 patient with lactic acidosis and ataxia."7.66Pyruvate-dehydrogenase complex in ataxic patients: enzyme deficiency in ataxic encephalopathy plus lactic acidosis and normal activity in Friedreich ataxia. ( Bottacchi, E; Cardace, G; Di Donato, S; Giovanardi-Rossi, P; Moschen, G; Uziel, G, 1982)
"However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated."5.317-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001)
"Increasing evidence from pathological and biochemical investigations suggests that mitochondrial metabolic impairment and oxidative stress play a crucial role in the pathogenesis of mitochondrial diseases, such as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, and various neurodegenerative disorders."5.12Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders. ( Ikawa, M; Okazawa, H; Yoneda, M, 2021)
" He was found to have high anion gap metabolic acidosis with significantly elevated lactate along with an elevated osmolal gap and calcium oxalate crystals in his urine."3.85Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning? ( Abu Sitta, E; Gaddam, M; Kanzy, A; Velagapudi, RK, 2017)
"D-lactic acidosis has been reported in patients after a variety of gastrointestinal surgeries, particularly jejunoileal bypass."3.77An extreme and life-threatening case of recurrent D-lactate encephalopathy. ( Htyte, N; Jones, J; Meisels, I; Sandhu, G; White, L, 2011)
"This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE)."3.71Determination of lactic acid level in systemic liquids in children with progressive encephalopathies. ( Bielińska-Bujniewicz, E; Emich-Widera, E; Marszał, E; Pietruszewski, J; Wojaczyńska-Stanek, K, 2002)
" All high-grade gliomas (n = 37) showed high choline and low or absent N-acetyl-L-aspartate and creatine along with lipid and/or lactate, whereas low-grade gliomas (n = 23) were characterized by low N-acetyl-aspartate and creatine and high choline and presence of only lactate."3.69Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995)
"The effects of hyperammonemia on brain function have been studied in three different experimental models in the rat: acute liver ischemia, urease-treated animals and methionine sulfoximine-treated animals."3.68Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation. ( Bosman, DK; Bovée, WM; Chamuleau, RA; De Graaf, AA; Deutz, NE; Jörning, GG; Maas, MA; Van Eijk, HM; vd Hulst, RW, 1990)
" Patients with mitochondrial encephalopathy with lactic acidosis and stroke-like episodes demonstrated only minor changes in redox state and in the behavior of the mitochondrial respiratory chain."3.68The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia. ( Capaldi, R; Chow, W; Glerum, DM; Lightowlers, R; Petrova-Benedict, R; Robinson, BH, 1990)
" We suggest that activated leukocytes consume CSF glucose and produce lactic acid and secrete protons, which causes the CSF and interstitial acidosis."3.67Brain acidosis in experimental pneumococcal meningitis. ( Andersen, NE; Gyring, J; Hansen, AJ; Laursen, H; Siesjö, BK, 1989)
" In the investigation it was found: lactic acidosis; stroke like episodes and calcification in the basal ganglia on computerized axial tomography; ragged red fibers on muscle biopsy and decreased of cytochrome C oxidase in the muscle tissue."3.67[MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case]. ( Abdalla, H; Lohr, A; Werneck, LC, 1987)
"Pyruvate dehydrogenase complex (PDHC) activity was measured in cultured fibroblasts from 12 patients with Friedreich's ataxia (FA), and in 1 patient with lactic acidosis and ataxia."3.66Pyruvate-dehydrogenase complex in ataxic patients: enzyme deficiency in ataxic encephalopathy plus lactic acidosis and normal activity in Friedreich ataxia. ( Bottacchi, E; Cardace, G; Di Donato, S; Giovanardi-Rossi, P; Moschen, G; Uziel, G, 1982)
"Moderate to severe neonatal encephalopathy in asphyxiated term infants is associated with a high risk of cerebral palsy (especially quadriplegic or dyskinetic type) and/or cognitive disorders."2.44[Definition of intrapartum asphyxia and effects on outcome]. ( Zupan Simunek, V, 2008)
"The hallmark of pediatric cerebral malaria (CM) is sequestration of parasitized red blood cells in the cerebral microvasculature."1.481.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria. ( Birbeck, GL; Glover, SJ; Haacke, EM; Hammond, CA; Kampondeni, SD; Lishimpi, K; Milner, DA; Mwenechanya, M; Potchen, MJ; Seydel, KB; Sinyangwe, SS; Taylor, TE; Utriainen, D; Zeli, E, 2018)
"On neurologic examination, he had ideomotor apraxia and incomplete Gerstmann syndrome that was characterized by acalculia, agraphia, and finger agnosia."1.38[A 68 year-old man presenting ideomotor apraxia and incomplete Gerstmann syndrome with multiple cystic lesions in the left hemisphere]. ( Kuroiwa, Y; Miyaji, Y; Miyasaki, H; Ning, Z; Suzuki, Y; Watanabe, D, 2012)
"Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a recently described disorder with autosomal recessive mode of inheritance."1.35Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings. ( Baskan, O; Gunal, DI; Isak, B; Koseoglu, M; Ozsahin, S; Scheper, GC; Uluc, K; van der Knaap, MS; Yildirim, KA, 2008)
"Heatstroke is characterized by hyperthermia, vasoplegic shock, and cerebral ischemia and hypoxia."1.33Resuscitation from experimental heatstroke by hyperbaric oxygen therapy. ( Gao, CJ; Li, WX; Lin, MT; Niu, KC; Tsai, HM, 2005)
"PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy."1.33Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006)
"The lack of cobalamin caused a severe encephalopathy in the infant, whose brain displayed a striking loss of volume and a delay of myelination."1.32Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion. ( Horstmann, M; Kohlschütter, A; Lukacs, Z; Neumaier-Probst, E; Steinfeld, R; Ullrich, K, 2003)
"Two adolescent females presented with encephalopathy and raised venous lactate."1.32Hashimoto's encephalopathy: an unusual cause of seizures in the intensive care unit. ( Janes, SE; Santosh, B; Thomas, D; Vyas, H, 2004)
"During hypoxemia, both the pretreatment with endotoxin and nicotine induced higher levels of extracellular lactate and peak lactate/pyruvate ratio compared with controls (54."1.31Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia. ( Amerio, G; Frøen, JF; Saugstad, OD; Stray-Pedersen, B, 2002)
"Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells."1.31Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000)
"However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated."1.317-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001)
"Three epidermoid cysts showed only lactate signal."1.30In vivo single-voxel proton MR spectroscopy in intracranial cystic masses. ( Chang, KH; Han, MC; Han, MH; Jung, HW; Kim, HD; Kim, SH; Seong, SO; Song, IC, 1998)
"D-Lactate-associated encephalopathy is a rare clinical syndrome characterized by dizziness, ataxia, confusion, headaches, memory loss, lethargy, and aggressiveness which may progress to frank but reversible coma."1.28D-lactate-associated encephalopathy after massive small-bowel resection. ( Carr, WC; Harig, JM; Kraft, SC; Scully, TB, 1989)
"However, distinction between untreated pyogenic meningitis and virus meningitis is rarely problematic in clinical practice, so routine use of the test as an emergency procedure offers no extra advantage."1.27How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis? ( Dunbar, EM; Hooper, J; Mandal, BK; Parker, L, 1983)
"The symptoms of D-lactate encephalopathy are quite sensitive, but not necessarily specific for this disorder."1.27D-lactate encephalopathy. ( Eckfeldt, JH; Ludvigsen, CW; Pierpont, GL; Thurn, JR, 1985)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199018 (20.22)18.7374
1990's17 (19.10)18.2507
2000's31 (34.83)29.6817
2010's16 (17.98)24.3611
2020's7 (7.87)2.80

Authors

AuthorsStudies
Nguyen, YTK1
Ha, HTT1
Nguyen, TH1
Nguyen, LN1
Kato, Y1
Yokokura, M1
Iwabuchi, T1
Murayama, C1
Harada, T1
Goto, T1
Tamayama, T1
Kameno, Y1
Wakuda, T1
Kuwabara, H1
Benner, S1
Senju, A1
Tsukada, H1
Nishizawa, S1
Ouchi, Y1
Yamasue, H1
Li, R1
Yang, Y1
Wang, H1
Zhang, T1
Duan, F1
Wu, K1
Yang, S1
Xu, K1
Jiang, X1
Sun, X1
Baheerathan, A1
Pitceathly, RD1
Curtis, C1
Davies, NW1
Ikawa, M1
Okazawa, H1
Yoneda, M1
Liu, YJ2
Liu, H1
Wang, SB1
Xiao, QM2
Sun, AH1
Li, YQ2
Wang, WZ2
Shibasaki, J1
Niwa, T1
Piedvache, A1
Tomiyasu, M1
Morisaki, N1
Fujii, Y1
Toyoshima, K1
Aida, N1
Gaddam, M1
Velagapudi, RK1
Abu Sitta, E1
Kanzy, A1
Potchen, MJ1
Kampondeni, SD1
Seydel, KB1
Haacke, EM1
Sinyangwe, SS1
Mwenechanya, M1
Glover, SJ1
Milner, DA1
Zeli, E1
Hammond, CA1
Utriainen, D1
Lishimpi, K1
Taylor, TE1
Birbeck, GL1
Short, JH1
Sen, A1
Soares, AA1
de Oliveira, AL1
Sá-Nakanishi, AB1
Comar, JF1
Rampazzo, AP1
Vicentini, FA1
Natali, MR1
Gomes da Costa, SM1
Bracht, A1
Peralta, RM1
Ma, GY1
Zhao, LJ1
Li, J1
Wang, P1
Caines, D1
Sinclair, M1
Wood, D1
Valverde, A1
Dyson, D1
Gaitero, L1
Nykamp, S1
Xin, L1
Lanz, B1
Lei, H1
Gruetter, R1
Amaral, AU1
Cecatto, C1
Seminotti, B1
Ribeiro, CA1
Lagranha, VL1
Pereira, CC1
de Oliveira, FH1
de Souza, DG1
Goodman, S1
Woontner, M1
Wajner, M1
Karkovska, M1
Smutok, O1
Gonchar, M1
Uluc, K1
Baskan, O1
Yildirim, KA1
Ozsahin, S1
Koseoglu, M1
Isak, B1
Scheper, GC1
Gunal, DI1
van der Knaap, MS3
Marcoux, J1
McArthur, DA1
Miller, C1
Glenn, TC1
Villablanca, P1
Martin, NA1
Hovda, DA1
Alger, JR2
Vespa, PM1
Nagel, A1
Graetz, D1
Schink, T1
Frieler, K1
Sakowitz, O1
Vajkoczy, P1
Sarrafzadeh, A1
Noda, K1
Tanikawa, R1
Sugimura, T1
Kawasaki, K1
Kimura, T1
Izumi, N1
Hashimoto, M1
Lin, YW1
Yu, CY1
Girard, N1
Htyte, N1
White, L1
Sandhu, G1
Jones, J1
Meisels, I1
Joardar, S1
Das, S1
Chatterjee, R1
Guha, G1
Hasmi, MA1
Takata, K1
Kinoshita, M1
Okuno, T1
Moriya, M1
Kohda, T1
Honorat, JA1
Sugimoto, T1
Kumanogoh, A1
Kayama, H1
Takeda, K1
Sakoda, S1
Nakatsuji, Y1
Danhier, F1
Ansorena, E1
Silva, JM1
Coco, R1
Le Breton, A1
Préat, V1
Miyaji, Y1
Miyasaki, H1
Ning, Z1
Watanabe, D1
Suzuki, Y1
Kuroiwa, Y1
Terek, D1
Koroglu, O1
Yalaz, M1
Gokben, S1
Calli, C1
Coker, M1
Kultursay, N1
Arefyeva, IA1
Semenova, JB1
Zubairaev, MS1
Kondrasheva, EA1
Moshkin, AV1
Frøen, JF1
Amerio, G1
Stray-Pedersen, B1
Saugstad, OD1
van der Voorn, P1
Barkhof, F1
Van Coster, R1
Krägeloh-Mann, I1
Feigenbaum, A1
Blaser, S1
Vles, JS1
Rieckmann, P1
Pouwels, PJ1
Baik, HM1
Choe, BY1
Son, BC1
Kim, MC1
Kim, EN1
Lee, HK1
Suh, TS1
ALTSCHULE, MD2
HENNEMAN, DH1
HOLLIDAY, P1
GONCZ, RM1
HEYCK, H1
PERRIN, GM1
HOLLIDAY, PD1
KUBO, T1
Horstmann, M1
Neumaier-Probst, E1
Lukacs, Z1
Steinfeld, R1
Ullrich, K1
Kohlschütter, A1
Nagae-Poetscher, LM1
Bibat, G1
Philippart, M2
Rosemberg, S1
Fatemi, A1
Lacerda, MT1
Costa, MO1
Kok, F1
Costa Leite, C1
Horská, A1
Barker, PB1
Naidu, S1
Grünewald, S1
Champion, MP1
Leonard, JV1
Schaper, J1
Morris, AA1
Janes, SE1
Santosh, B1
Thomas, D1
Vyas, H1
Tsai, HM1
Gao, CJ1
Li, WX1
Lin, MT1
Niu, KC1
van Hulst, RA1
Drenthen, J1
Haitsma, JJ1
Lameris, TW1
Visser, GH1
Klein, J1
Lachmann, B1
Roerick, O1
Seitz, T1
Mauser-Weber, P1
Palmaers, T1
Weyand, M1
Cesnjevar, R1
Lange, T1
Dydak, U1
Roberts, TP1
Rowley, HA1
Bjeljac, M1
Boesiger, P1
Petzold, GC1
Bohner, G1
Klingebiel, R1
Amberger, N1
Zschenderlein, R1
Huisman, TA1
Klein, A1
Werner, B1
Straube, T1
Boltshauser, E1
Di Costanzo, A1
Trojsi, F1
Tosetti, M1
Schirmer, T2
Lechner, SM1
Popolizio, T1
Scarabino, T1
Labauge, P1
Roullet, E1
Boespflug-Tanguy, O1
Nicoli, F1
Le Fur, Y1
Cozzone, PJ1
Ducreux, D1
Rodriguez, D1
Basheer, SN1
Waters, PJ1
Lam, CW1
Acquaviva-Bourdain, C1
Hendson, G1
Poskitt, K1
Hukin, J1
Zupan Simunek, V1
White, NJ1
Warrell, DA1
Chanthavanich, P1
Looareesuwan, S1
Warrell, MJ1
Krishna, S1
Williamson, DH1
Turner, RC1
Uziel, G1
Bottacchi, E1
Moschen, G1
Giovanardi-Rossi, P1
Cardace, G1
Di Donato, S1
Mandal, BK1
Dunbar, EM1
Hooper, J1
Parker, L1
Hansen, TL1
Christensen, E1
Brandt, NJ1
Poptani, H1
Gupta, RK1
Roy, R1
Pandey, R1
Jain, VK1
Chhabra, DK1
Dotti, MT1
Manneschi, L1
Federico, A1
Tedeschi, G1
Schiffmann, R1
Barton, NW1
Shih, HH1
Gospe, SM1
Brady, RO1
Di Chiro, G1
Siciliano, G1
Rossi, B1
Martini, A1
Angelini, C1
Martinuzzi, A1
Lodi, R1
Zaniol, P1
Barbiroli, B1
Muratorio, A1
Romero, IA1
Lister, T1
Richards, HK1
Seville, MP1
Wylie, SP1
Ray, DE1
Maran, A1
Cranston, I1
Lomas, J1
Macdonald, I1
Amiel, SA1
Erecińska, M1
Nelson, D1
Hiraoka, A1
Akai, J1
Tominaga, I1
Hattori, M1
Sasaki, H1
Arato, T1
Hingorani, AD1
Macdougall, IC1
Browne, M1
Walker, RW1
Tomson, CR1
Holshouser, BA1
Ashwal, S1
Luh, GY1
Shu, S1
Kahlon, S1
Auld, KL1
Tomasi, LG1
Perkin, RM1
Hinshaw, DB1
Wakulicz-Deja, A1
Paszek, P1
Chang, KH1
Song, IC1
Kim, SH1
Han, MH1
Kim, HD1
Seong, SO1
Jung, HW1
Han, MC1
Ohki, S1
Togari, H1
Sobajima, H1
Fujimoto, S1
Kobayashi, M1
Hyodo, J1
Robertson, NJ1
Cox, IJ1
Cowan, FM1
Counsell, SJ1
Azzopardi, D1
Edwards, AD1
Kriegstein, AR1
Shungu, DC1
Millar, WS1
Armitage, BA1
Brust, JC1
Chillrud, S1
Goldman, J1
Lynch, T1
Harada, M1
Hisaoka, S1
Mori, K1
Yoneda, K1
Noda, S1
Nishitani, H1
Wilken, B1
Dechent, P1
Herms, J1
Maxton, C1
Markakis, E1
Hanefeld, F1
Frahm, J2
Spencer, JA1
Paterson-Brown, S1
Brocklehurst, P1
Blüml, S1
Moreno, A1
Hwang, JH1
Ross, BD1
Burtscher, IM1
Holtås, S1
Park, WS1
Chang, YS1
Lee, M1
Auer, DP1
Gössl, C1
Czisch, M1
Marszał, E1
Wojaczyńska-Stanek, K1
Pietruszewski, J1
Emich-Widera, E1
Bielińska-Bujniewicz, E1
Bosman, DK1
Deutz, NE1
De Graaf, AA1
vd Hulst, RW1
Van Eijk, HM1
Bovée, WM1
Maas, MA1
Jörning, GG1
Chamuleau, RA1
Robinson, BH1
Glerum, DM1
Chow, W1
Petrova-Benedict, R1
Lightowlers, R1
Capaldi, R1
Andersen, NE1
Gyring, J1
Hansen, AJ1
Laursen, H1
Siesjö, BK1
Mizuno, Y1
Ishiguro, K1
Okamoto, K1
Morimatsu, M1
Hirai, S1
Bruhn, H1
Gyngell, ML1
Merboldt, KD1
Hänicke, W1
Sauter, R1
Hamburger, C1
Scully, TB1
Kraft, SC1
Carr, WC1
Harig, JM1
Khan, NA1
Guevara, P1
Sotelo, J1
Werneck, LC1
Abdalla, H1
Lohr, A1
Yokochi, K1
Tatsumi, C1
Takahashi, M1
Yorifuji, S1
Nishikawa, Y1
Kitaguchi, M1
Hashimoto, S1
Tarui, S1
Al-Mateen, M1
Shields, WD1
Thurn, JR1
Pierpont, GL1
Ludvigsen, CW1
Eckfeldt, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819]256 participants (Anticipated)Observational2021-01-02Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for lactic acid and Brain Disorders

ArticleYear
The role of SLC transporters for brain health and disease.
    Cellular and molecular life sciences : CMLS, 2021, Dec-31, Volume: 79, Issue:1

    Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain; Brain Diseases; Humans; Lactic Acid; Membrane Trans

2021
Lactate and Lactylation in the Brain: Current Progress and Perspectives.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:6

    Topics: Brain; Brain Diseases; Energy Metabolism; Glycolysis; Humans; Lactic Acid

2023
CSF lactate.
    Practical neurology, 2020, Volume: 20, Issue:4

    Topics: Adult; Biomarkers; Brain Diseases; Central Nervous System Infections; Enterovirus; Female; Humans; L

2020
Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders.
    Biochimica et biophysica acta. General subjects, 2021, Volume: 1865, Issue:3

    Topics: Acidosis, Lactic; Brain Diseases; Electron Transport; Fatty Acids; Glucose; Humans; Lactic Acid; Mag

2021
[Magnetic resonance spectroscopy for cerebral imaging].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:6

    Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea

2010
PLGA-based nanoparticles: an overview of biomedical applications.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Jul-20, Volume: 161, Issue:2

    Topics: Animals; Bacterial Infections; Brain Diseases; Cardiovascular Diseases; Drug Delivery Systems; Human

2012
Proton MR spectroscopy of the brain at 3 T: an update.
    European radiology, 2007, Volume: 17, Issue:7

    Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Cortex; Choline; Creatine

2007
[Definition of intrapartum asphyxia and effects on outcome].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2008, Volume: 37 Suppl 1

    Topics: Acidosis; Apgar Score; Biomarkers; Brain Diseases; Cerebral Palsy; Female; Fetal Blood; Fetal Hypoxi

2008
Proton MR spectroscopy in clinical routine.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 13, Issue:4

    Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Humans; Lactic Acid; Magnetic Resonance Spectrosco

2001

Trials

2 trials available for lactic acid and Brain Disorders

ArticleYear
Protection by lactate of cerebral function during hypoglycaemia.
    Lancet (London, England), 1994, Jan-01, Volume: 343, Issue:8888

    Topics: Adult; Blood Chemical Analysis; Brain; Brain Diseases; Cognition; Hormones; Humans; Hypoglycemia; La

1994
Diagnose progressive encephalopathy applying the rough set theory.
    International journal of medical informatics, 1997, Volume: 46, Issue:2

    Topics: Adolescent; Biopsy; Brain Diseases; Child; Child, Preschool; Decision Support Techniques; Diagnosis,

1997

Other Studies

78 other studies available for lactic acid and Brain Disorders

ArticleYear
Lower Availability of Mitochondrial Complex I in Anterior Cingulate Cortex in Autism: A Positron Emission Tomography Study.
    The American journal of psychiatry, 2023, 04-01, Volume: 180, Issue:4

    Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Brain; Brain Diseases; Case-Control Studies; Ele

2023
[Correlation between early eeg dual-frequency index monitoring combined with lactic acid clearance rate and delayed encephalopathy with acute severe carbon monoxide poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2021, Apr-20, Volume: 39, Issue:4

    Topics: Brain Diseases; Carbon Monoxide Poisoning; Humans; Lactic Acid; Prognosis; Retrospective Studies

2021
Comparison of Predictive Values of Magnetic Resonance Biomarkers Based on Scan Timing in Neonatal Encephalopathy Following Therapeutic Hypothermia.
    The Journal of pediatrics, 2021, Volume: 239

    Topics: Aspartic Acid; Biomarkers; Brain Diseases; Dipeptides; Gray Matter; Humans; Hypothermia, Induced; In

2021
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning?
    BMJ case reports, 2017, Oct-15, Volume: 2017

    Topics: Acid-Base Equilibrium; Acidosis; Anticonvulsants; Brain Diseases; Calcium Oxalate; Cognitive Dysfunc

2017
1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:2

    Topics: Adolescent; Blood Glucose; Brain Diseases; Child; Child, Preschool; Female; Gadolinium; Humans; Infa

2018
62-Year-Old Man With Encephalopathy and Fatigue After Allogeneic Bone Marrow Transplant.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Bone Marrow Transplantation; Brain Diseases; Consciousness Disorders; Cytomegalovirus Infections; Ep

2018
Effects of an Agaricus blazei aqueous extract pretreatment on paracetamol-induced brain and liver injury in rats.
    BioMed research international, 2013, Volume: 2013

    Topics: Acetaminophen; Administration, Oral; Agaricus; Alanine; Animals; Antioxidants; Biomarkers; Brain; Br

2013
[The relationship between lactate clearance rate and delayed encephalopathy after acute carbon monoxide poisoning].
    Zhonghua wei zhong bing ji jiu yi xue, 2013, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Diseases; Carbon Monoxide Poisoning; Child; Female

2013
Evaluation of cerebrospinal fluid lactate and plasma lactate concentrations in anesthetized dogs with and without intracranial disease.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2013, Volume: 77, Issue:4

    Topics: Animals; Brain Diseases; Case-Control Studies; Dog Diseases; Dogs; Female; Lactic Acid; Male; Prospe

2013
Assessment of metabolic fluxes in the mouse brain in vivo using 1H-[13C] NMR spectroscopy at 14.1 Tesla.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:5

    Topics: Amino Acids; Animals; Brain; Brain Chemistry; Brain Diseases; Carbon Isotopes; Glucose; Humans; Lact

2015
Experimental evidence that bioenergetics disruption is not mainly involved in the brain injury of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.
    Brain research, 2015, Sep-16, Volume: 1620

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases; Brain Diseases, Metabolic; Cerebral C

2015
Laboratory Prototype of Bioreactor for Oxidation of Toxic D-Lactate Using Yeast Cells Overproducing D-Lactate Cytochrome c Oxidoreductase.
    BioMed research international, 2016, Volume: 2016

    Topics: Bioreactors; Brain Diseases; Fermentation; Foodborne Diseases; Glucose; Lactate Dehydrogenases; Lact

2016
Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings.
    Journal of the neurological sciences, 2008, Oct-15, Volume: 273, Issue:1-2

    Topics: Adult; Aspartate-tRNA Ligase; Aspartic Acid; Brain Diseases; Brain Stem; Creatine; Humans; Lactic Ac

2008
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
    Critical care medicine, 2008, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Stud

2008
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
    Journal of neurosurgery, 2009, Volume: 111, Issue:1

    Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutam

2009
Use of bioabsorbable plates for cranial fixation.
    Neurologia medico-chirurgica, 2009, Volume: 49, Issue:11

    Topics: Absorbable Implants; Biocompatible Materials; Bone Plates; Bone Screws; Brain Diseases; Craniotomy;

2009
Reversible focal splenium lesion--MRS study of a different etiology.
    Acta neurologica Taiwanica, 2009, Volume: 18, Issue:3

    Topics: Adult; Aspartic Acid; Brain Diseases; Brain Mapping; Corpus Callosum; Diffusion Magnetic Resonance I

2009
An extreme and life-threatening case of recurrent D-lactate encephalopathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:4

    Topics: Acidosis, Lactic; Brain Diseases; Humans; Kidney Failure, Chronic; Lactic Acid; Male; Middle Aged; R

2011
Unilateral basal-ganglia involvement likely due to valproate-induced hyperammonemic encephalopathy.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:4

    Topics: Anticonvulsants; Basal Ganglia; Brain Diseases; Child, Preschool; Diffusion Magnetic Resonance Imagi

2012
The lactic acid bacterium Pediococcus acidilactici suppresses autoimmune encephalomyelitis by inducing IL-10-producing regulatory T cells.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Administration, Oral; Animals; Brain Diseases; Encephalitis; Female; Hashimoto Disease; Interleukin-

2011
[A 68 year-old man presenting ideomotor apraxia and incomplete Gerstmann syndrome with multiple cystic lesions in the left hemisphere].
    Rinsho shinkeigaku = Clinical neurology, 2012, Volume: 52, Issue:9

    Topics: Aged; Apraxia, Ideomotor; Brain Diseases; Cerebrovascular Circulation; Cysts; Electroencephalography

2012
Diagnostic tools of early brain disturbances in an asymptomatic neonate with maple syrup urine disease.
    Neuropediatrics, 2013, Volume: 44, Issue:4

    Topics: Aspartic Acid; Brain Diseases; Brain Waves; Consanguinity; Developmental Disabilities; Diet; Diet, C

2013
Analysis of fluid in craniopharyngioma-related cysts in children: proteins, lactate and pH.
    Acta neurochirurgica, 2002, Volume: 144, Issue:6

    Topics: Adolescent; Albumins; Blood-Brain Barrier; Brain Diseases; Brain Neoplasms; Child; Child, Preschool;

2002
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia.
    Biology of the neonate, 2002, Volume: 82, Issue:3

    Topics: Animals; Animals, Newborn; Blood Pressure; Brain Diseases; Corpus Striatum; Endotoxins; Escherichia

2002
A new leukoencephalopathy with brainstem and spinal cord involvement and high lactate.
    Annals of neurology, 2003, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Brain Diseases; Brain Stem; Child; Female; Humans; Lactic Acid; Magnetic Resonanc

2003
Feasibility of proton chemical shift imaging with a stereotactic headframe.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:1

    Topics: Adult; Biopsy, Needle; Brain; Brain Diseases; Choline; Creatine; Feasibility Studies; Female; Humans

2003
Carbohydrate metabolism in brain disease. VI. Lactate metabolism after infusion of sodium d-lactate in manic-depressive and schizophrenic psychoses.
    A.M.A. archives of internal medicine, 1956, Volume: 98, Issue:1

    Topics: Bipolar Disorder; Brain Diseases; Carbohydrate Metabolism; Humans; Lactic Acid; Mental Disorders; Ps

1956
[On the problem of cryptogenetic processes of brain atrophy: quantitative measurements of cerebral circulation and cerebral glucose, lactic acid and pyruvic acid metabolism].
    Psychiatria et neurologia, 1961, Volume: 142

    Topics: Atrophy; Brain; Brain Diseases; Cerebrovascular Circulation; Glucose; Humans; Lactates; Lactic Acid;

1961
Carbohydrate metabolism in brain disease. XIII. Effect of lactate infusion on blood keto-acid concentrations in schizophremic and manic-depressive psychoses.
    Archives of internal medicine, 1960, Volume: 105

    Topics: Bipolar Disorder; Brain Diseases; Carbohydrate Metabolism; Humans; Keto Acids; Lactates; Lactic Acid

1960
[Experimental and clinical studies of the carbohydrate metabolism in injured brain with special reference to the glycogen and lactate contents].
    [Fukushima igaku zasshi] Fukushima medical journal, 1961, Volume: 11

    Topics: Brain; Brain Diseases; Carbohydrate Metabolism; Glycogen; Humans; Lactates; Lactic Acid

1961
Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion.
    Neuropediatrics, 2003, Volume: 34, Issue:5

    Topics: Brain Diseases; Choline Deficiency; Humans; Infant; Lactic Acid; Magnetic Resonance Spectroscopy; Ma

2003
Leukoencephalopathy, cerebral calcifications, and cysts: new observations.
    Neurology, 2004, Apr-13, Volume: 62, Issue:7

    Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Calcinosis; Central Nervous System Cysts; Child; C

2004
Biotinidase deficiency: a treatable leukoencephalopathy.
    Neuropediatrics, 2004, Volume: 35, Issue:4

    Topics: Biotinidase Deficiency; Brain; Brain Diseases; Follow-Up Studies; Humans; Infant; Lactic Acid; Male;

2004
Hashimoto's encephalopathy: an unusual cause of seizures in the intensive care unit.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2004, Volume: 5, Issue:6

    Topics: Adolescent; Autoantibodies; Brain Diseases; Cognition Disorders; Female; Glucocorticoids; Humans; In

2004
Resuscitation from experimental heatstroke by hyperbaric oxygen therapy.
    Critical care medicine, 2005, Volume: 33, Issue:4

    Topics: Animals; Biomarkers; Brain Diseases; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; H

2005
Effects of hyperbaric treatment in cerebral air embolism on intracranial pressure, brain oxygenation, and brain glucose metabolism in the pig.
    Critical care medicine, 2005, Volume: 33, Issue:4

    Topics: Animals; Brain; Brain Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Electroenc

2005
Low-flow perfusion via the innominate artery during aortic arch operations provides only limited somatic circulatory support.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 29, Issue:4

    Topics: Acid-Base Imbalance; Animals; Animals, Newborn; Aorta, Thoracic; Body Temperature; Brachiocephalic T

2006
Pitfalls in lactate measurements at 3T.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:4

    Topics: Brain Diseases; False Negative Reactions; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Phan

2006
Adult onset leucoencephalopathy with brain stem and spinal cord involvement and normal lactate.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:7

    Topics: Adult; Age of Onset; Brain Chemistry; Brain Diseases; Brain Stem; Female; Gait Ataxia; Humans; Lacti

2006
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion

2006
Familial, adult onset form of leukoencephalopathy with brain stem and spinal cord involvement: inconstant high brain lactate and very slow disease progression.
    European neurology, 2007, Volume: 58, Issue:1

    Topics: Adult; Brain Chemistry; Brain Diseases; Brain Stem; Disease Progression; Family Health; Female; Huma

2007
Isolated sulfite oxidase deficiency in the newborn: lactic acidaemia and leukoencephalopathy.
    Neuropediatrics, 2007, Volume: 38, Issue:1

    Topics: Acidosis, Lactic; Brain Diseases; Homocysteine; Humans; Infant, Newborn; Lactic Acid; Male; Sulfite

2007
Severe hypoglycemia and hyperinsulinemia in falciparum malaria.
    The New England journal of medicine, 1983, Jul-14, Volume: 309, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Brain Diseases; C-Peptide; Child;

1983
Pyruvate-dehydrogenase complex in ataxic patients: enzyme deficiency in ataxic encephalopathy plus lactic acidosis and normal activity in Friedreich ataxia.
    Italian journal of neurological sciences, 1982, Volume: 3, Issue:4

    Topics: Acidosis; Adolescent; Ataxia; Brain Diseases; Fibroblasts; Friedreich Ataxia; Humans; Lactates; Lact

1982
How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis?
    The Journal of infection, 1983, Volume: 6, Issue:3

    Topics: Brain Diseases; Diagnosis, Differential; Humans; Lactates; Lactic Acid; Meningitis; Meningitis, Vira

1983
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
    Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:2

    Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fi

1982
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea

1995
Mitochondrial enzyme deficiency in cerebrotendinous xanthomatosis.
    Journal of the neurological sciences, 1995, Volume: 129, Issue:2

    Topics: Adult; Biopsy; Brain Diseases; Electron Transport; Female; Humans; Lactates; Lactic Acid; Mitochondr

1995
Proton magnetic resonance spectroscopic imaging in childhood ataxia with diffuse central nervous system hypomyelination.
    Neurology, 1995, Volume: 45, Issue:8

    Topics: Aspartic Acid; Ataxia; Brain; Brain Diseases; Child, Preschool; Choline; Creatine; Female; Gaucher D

1995
Myophosphorylase deficiency affects muscle mitochondrial respiration as shown by 31P-MR spectroscopy in a case with associated multifocal encephalopathy.
    Journal of the neurological sciences, 1995, Volume: 128, Issue:1

    Topics: Adult; Aerobiosis; Brain Diseases; DNA; Electrocardiography; Energy Metabolism; Exercise; Glycogen;

1995
Early metabolic changes during m-Dinitrobenzene neurotoxicity and the possible role of oxidative stress.
    Free radical biology & medicine, 1995, Volume: 18, Issue:2

    Topics: Animals; Animals, Newborn; Astrocytes; Blood-Brain Barrier; Brain; Brain Diseases; Cell Death; Cells

1995
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
    Journal of neurochemistry, 1994, Volume: 63, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Amin

1994
Capillary zone electrophoretic determination of organic acids in cerebrospinal fluid from patients with central nervous system diseases.
    Journal of chromatography. A, 1994, Sep-30, Volume: 680, Issue:1

    Topics: Brain Diseases; Cerebral Infarction; Electrophoresis; Humans; Lactates; Lactic Acid; Meningitis, Bac

1994
Successful treatment of acute D-lactate encephalopathy by haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:11

    Topics: Acute Disease; Adult; Brain Diseases; Female; Humans; Intestine, Small; Lactates; Lactic Acid; Posto

1993
Proton MR spectroscopy after acute central nervous system injury: outcome prediction in neonates, infants, and children.
    Radiology, 1997, Volume: 202, Issue:2

    Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Brain Injuries; Child; Choline; Discriminant Analy

1997
In vivo single-voxel proton MR spectroscopy in intracranial cystic masses.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:3

    Topics: Adult; Amino Acids; Brain Abscess; Brain Diseases; Brain Neoplasms; Cysticercosis; Cysts; Female; Ga

1998
Lactate attenuates neuron specific enolase elevation in newborn rats.
    Pediatric neurology, 1999, Volume: 21, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biomarkers; Brain; Brain Diseases; Hypoxia; Lactic Acid; Phosphopyr

1999
Cerebral intracellular lactic alkalosis persisting months after neonatal encephalopathy measured by magnetic resonance spectroscopy.
    Pediatric research, 1999, Volume: 46, Issue:3

    Topics: Brain; Brain Diseases; Cytoplasm; Fetal Hypoxia; Humans; Infant; Infant, Newborn; Lactic Acid; Magne

1999
Leukoencephalopathy and raised brain lactate from heroin vapor inhalation ("chasing the dragon")
    Neurology, 1999, Nov-10, Volume: 53, Issue:8

    Topics: Administration, Inhalation; Adult; Antioxidants; Biopsy; Brain; Brain Diseases; Female; Heroin; Huma

1999
Differences in water diffusion and lactate production in two different types of postinfectious encephalopathy.
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 11, Issue:5

    Topics: Body Water; Brain Chemistry; Brain Diseases; Child; Echo-Planar Imaging; Encephalomyelitis, Acute Di

2000
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
    Pediatric neurology, 2000, Volume: 23, Issue:1

    Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms;

2000
Fetal blood lactate concentration.
    American journal of obstetrics and gynecology, 2000, Volume: 183, Issue:5

    Topics: Brain Diseases; Fetal Blood; Humans; Lactic Acid; Osmolar Concentration

2000
1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders.
    NMR in biomedicine, 2001, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Canavan Disease; Carbon Isotopes; Chi

2001
7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet.
    Biology of the neonate, 2001, Volume: 80, Issue:1

    Topics: Animals; Animals, Newborn; Blood Glucose; Brain Diseases; Cerebral Cortex; Cerebrospinal Fluid; Dise

2001
Improved analysis of 1H-MR spectra in the presence of mobile lipids.
    Magnetic resonance in medicine, 2001, Volume: 46, Issue:3

    Topics: Alanine; Artifacts; Brain; Brain Diseases; Brain Neoplasms; Glioblastoma; Glioma; Humans; Image Enha

2001
Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.
    Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:3

    Topics: Adolescent; Brain Diseases; Case-Control Studies; Cerebrovascular Disorders; Child; Child, Preschool

2002
Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:2

    Topics: Acute Disease; Ammonia; Animals; Brain; Brain Diseases; Electroencephalography; Glutamates; Glutamic

1990
The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia.
    Pediatric research, 1990, Volume: 28, Issue:5

    Topics: Acidosis, Lactic; Brain Diseases; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Fibroblasts; Hum

1990
Brain acidosis in experimental pneumococcal meningitis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:3

    Topics: Acidosis; Animals; Blood Glucose; Brain Diseases; Carbon Dioxide; Glucose; Humans; Hydrogen-Ion Conc

1989
[A case of mitochondrial encephalomyopathy characterized by repeated stroke-like episodes].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:3

    Topics: Adult; Brain Diseases; Cerebrovascular Disorders; Electroencephalography; Epilepsies, Myoclonic; Hum

1989
Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.
    Radiology, 1989, Volume: 172, Issue:2

    Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Cysts;

1989
D-lactate-associated encephalopathy after massive small-bowel resection.
    Journal of clinical gastroenterology, 1989, Volume: 11, Issue:4

    Topics: Acidosis, Lactic; Adolescent; Brain Diseases; Humans; Ileum; Intestinal Absorption; Isomerism; Jejun

1989
Influence of in vitro lactic acidosis on central nervous system neurons.
    Pathologie-biologie, 1989, Volume: 37, Issue:6

    Topics: Acidosis, Lactic; Brain Diseases; Cells, Cultured; Central Nervous System; Chromatin; Citrates; Citr

1989
[MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case].
    Arquivos de neuro-psiquiatria, 1987, Volume: 45, Issue:3

    Topics: Acidosis, Lactic; Brain Diseases; Cerebrovascular Disorders; Child; Electron Transport Complex IV; H

1987
[Neurological approach to mitochondrial abnormalities].
    No to hattatsu = Brain and development, 1987, Volume: 19, Issue:2

    Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Cytochrome-c Oxidase Deficiency; Female; Humans

1987
Mitochondrial encephalomyopathy with sleep apnea.
    European neurology, 1988, Volume: 28, Issue:2

    Topics: Brain Diseases; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria; Muscles; Muscular Di

1988
Rett syndrome. A commonly overlooked progressive encephalopathy in girls.
    American journal of diseases of children (1960), 1986, Volume: 140, Issue:8

    Topics: Adolescent; Adult; Ataxia; Basal Ganglia Diseases; Brain Diseases; Child; Child, Preschool; Dementia

1986
D-lactate encephalopathy.
    The American journal of medicine, 1985, Volume: 79, Issue:6

    Topics: Acidosis; Adult; Brain Diseases; Female; Humans; Jejunoileal Bypass; Lactates; Lactic Acid; Male; Mi

1985