lactic acid has been researched along with Brain Diseases in 89 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the investigation it was found: lactic acidosis; stroke like episodes and calcification in the basal ganglia on computerized axial tomography; ragged red fibers on muscle biopsy and decreased of cytochrome C oxidase in the muscle tissue." | 7.67 | [MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case]. ( Abdalla, H; Lohr, A; Werneck, LC, 1987) |
| "Pyruvate dehydrogenase complex (PDHC) activity was measured in cultured fibroblasts from 12 patients with Friedreich's ataxia (FA), and in 1 patient with lactic acidosis and ataxia." | 7.66 | Pyruvate-dehydrogenase complex in ataxic patients: enzyme deficiency in ataxic encephalopathy plus lactic acidosis and normal activity in Friedreich ataxia. ( Bottacchi, E; Cardace, G; Di Donato, S; Giovanardi-Rossi, P; Moschen, G; Uziel, G, 1982) |
| "However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated." | 5.31 | 7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001) |
| "Increasing evidence from pathological and biochemical investigations suggests that mitochondrial metabolic impairment and oxidative stress play a crucial role in the pathogenesis of mitochondrial diseases, such as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, and various neurodegenerative disorders." | 5.12 | Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders. ( Ikawa, M; Okazawa, H; Yoneda, M, 2021) |
| " He was found to have high anion gap metabolic acidosis with significantly elevated lactate along with an elevated osmolal gap and calcium oxalate crystals in his urine." | 3.85 | Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning? ( Abu Sitta, E; Gaddam, M; Kanzy, A; Velagapudi, RK, 2017) |
| "D-lactic acidosis has been reported in patients after a variety of gastrointestinal surgeries, particularly jejunoileal bypass." | 3.77 | An extreme and life-threatening case of recurrent D-lactate encephalopathy. ( Htyte, N; Jones, J; Meisels, I; Sandhu, G; White, L, 2011) |
| "This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE)." | 3.71 | Determination of lactic acid level in systemic liquids in children with progressive encephalopathies. ( Bielińska-Bujniewicz, E; Emich-Widera, E; Marszał, E; Pietruszewski, J; Wojaczyńska-Stanek, K, 2002) |
| " All high-grade gliomas (n = 37) showed high choline and low or absent N-acetyl-L-aspartate and creatine along with lipid and/or lactate, whereas low-grade gliomas (n = 23) were characterized by low N-acetyl-aspartate and creatine and high choline and presence of only lactate." | 3.69 | Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995) |
| "The effects of hyperammonemia on brain function have been studied in three different experimental models in the rat: acute liver ischemia, urease-treated animals and methionine sulfoximine-treated animals." | 3.68 | Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation. ( Bosman, DK; Bovée, WM; Chamuleau, RA; De Graaf, AA; Deutz, NE; Jörning, GG; Maas, MA; Van Eijk, HM; vd Hulst, RW, 1990) |
| " Patients with mitochondrial encephalopathy with lactic acidosis and stroke-like episodes demonstrated only minor changes in redox state and in the behavior of the mitochondrial respiratory chain." | 3.68 | The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia. ( Capaldi, R; Chow, W; Glerum, DM; Lightowlers, R; Petrova-Benedict, R; Robinson, BH, 1990) |
| " We suggest that activated leukocytes consume CSF glucose and produce lactic acid and secrete protons, which causes the CSF and interstitial acidosis." | 3.67 | Brain acidosis in experimental pneumococcal meningitis. ( Andersen, NE; Gyring, J; Hansen, AJ; Laursen, H; Siesjö, BK, 1989) |
| " In the investigation it was found: lactic acidosis; stroke like episodes and calcification in the basal ganglia on computerized axial tomography; ragged red fibers on muscle biopsy and decreased of cytochrome C oxidase in the muscle tissue." | 3.67 | [MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case]. ( Abdalla, H; Lohr, A; Werneck, LC, 1987) |
| "Pyruvate dehydrogenase complex (PDHC) activity was measured in cultured fibroblasts from 12 patients with Friedreich's ataxia (FA), and in 1 patient with lactic acidosis and ataxia." | 3.66 | Pyruvate-dehydrogenase complex in ataxic patients: enzyme deficiency in ataxic encephalopathy plus lactic acidosis and normal activity in Friedreich ataxia. ( Bottacchi, E; Cardace, G; Di Donato, S; Giovanardi-Rossi, P; Moschen, G; Uziel, G, 1982) |
| "Moderate to severe neonatal encephalopathy in asphyxiated term infants is associated with a high risk of cerebral palsy (especially quadriplegic or dyskinetic type) and/or cognitive disorders." | 2.44 | [Definition of intrapartum asphyxia and effects on outcome]. ( Zupan Simunek, V, 2008) |
| "The hallmark of pediatric cerebral malaria (CM) is sequestration of parasitized red blood cells in the cerebral microvasculature." | 1.48 | 1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria. ( Birbeck, GL; Glover, SJ; Haacke, EM; Hammond, CA; Kampondeni, SD; Lishimpi, K; Milner, DA; Mwenechanya, M; Potchen, MJ; Seydel, KB; Sinyangwe, SS; Taylor, TE; Utriainen, D; Zeli, E, 2018) |
| "On neurologic examination, he had ideomotor apraxia and incomplete Gerstmann syndrome that was characterized by acalculia, agraphia, and finger agnosia." | 1.38 | [A 68 year-old man presenting ideomotor apraxia and incomplete Gerstmann syndrome with multiple cystic lesions in the left hemisphere]. ( Kuroiwa, Y; Miyaji, Y; Miyasaki, H; Ning, Z; Suzuki, Y; Watanabe, D, 2012) |
| "Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a recently described disorder with autosomal recessive mode of inheritance." | 1.35 | Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings. ( Baskan, O; Gunal, DI; Isak, B; Koseoglu, M; Ozsahin, S; Scheper, GC; Uluc, K; van der Knaap, MS; Yildirim, KA, 2008) |
| "Heatstroke is characterized by hyperthermia, vasoplegic shock, and cerebral ischemia and hypoxia." | 1.33 | Resuscitation from experimental heatstroke by hyperbaric oxygen therapy. ( Gao, CJ; Li, WX; Lin, MT; Niu, KC; Tsai, HM, 2005) |
| "PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy." | 1.33 | Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006) |
| "The lack of cobalamin caused a severe encephalopathy in the infant, whose brain displayed a striking loss of volume and a delay of myelination." | 1.32 | Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion. ( Horstmann, M; Kohlschütter, A; Lukacs, Z; Neumaier-Probst, E; Steinfeld, R; Ullrich, K, 2003) |
| "Two adolescent females presented with encephalopathy and raised venous lactate." | 1.32 | Hashimoto's encephalopathy: an unusual cause of seizures in the intensive care unit. ( Janes, SE; Santosh, B; Thomas, D; Vyas, H, 2004) |
| "During hypoxemia, both the pretreatment with endotoxin and nicotine induced higher levels of extracellular lactate and peak lactate/pyruvate ratio compared with controls (54." | 1.31 | Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia. ( Amerio, G; Frøen, JF; Saugstad, OD; Stray-Pedersen, B, 2002) |
| "Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells." | 1.31 | Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000) |
| "However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated." | 1.31 | 7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001) |
| "Three epidermoid cysts showed only lactate signal." | 1.30 | In vivo single-voxel proton MR spectroscopy in intracranial cystic masses. ( Chang, KH; Han, MC; Han, MH; Jung, HW; Kim, HD; Kim, SH; Seong, SO; Song, IC, 1998) |
| "D-Lactate-associated encephalopathy is a rare clinical syndrome characterized by dizziness, ataxia, confusion, headaches, memory loss, lethargy, and aggressiveness which may progress to frank but reversible coma." | 1.28 | D-lactate-associated encephalopathy after massive small-bowel resection. ( Carr, WC; Harig, JM; Kraft, SC; Scully, TB, 1989) |
| "However, distinction between untreated pyogenic meningitis and virus meningitis is rarely problematic in clinical practice, so routine use of the test as an emergency procedure offers no extra advantage." | 1.27 | How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis? ( Dunbar, EM; Hooper, J; Mandal, BK; Parker, L, 1983) |
| "The symptoms of D-lactate encephalopathy are quite sensitive, but not necessarily specific for this disorder." | 1.27 | D-lactate encephalopathy. ( Eckfeldt, JH; Ludvigsen, CW; Pierpont, GL; Thurn, JR, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (20.22) | 18.7374 |
| 1990's | 17 (19.10) | 18.2507 |
| 2000's | 31 (34.83) | 29.6817 |
| 2010's | 16 (17.98) | 24.3611 |
| 2020's | 7 (7.87) | 2.80 |
| Authors | Studies |
|---|---|
| Nguyen, YTK | 1 |
| Ha, HTT | 1 |
| Nguyen, TH | 1 |
| Nguyen, LN | 1 |
| Kato, Y | 1 |
| Yokokura, M | 1 |
| Iwabuchi, T | 1 |
| Murayama, C | 1 |
| Harada, T | 1 |
| Goto, T | 1 |
| Tamayama, T | 1 |
| Kameno, Y | 1 |
| Wakuda, T | 1 |
| Kuwabara, H | 1 |
| Benner, S | 1 |
| Senju, A | 1 |
| Tsukada, H | 1 |
| Nishizawa, S | 1 |
| Ouchi, Y | 1 |
| Yamasue, H | 1 |
| Li, R | 1 |
| Yang, Y | 1 |
| Wang, H | 1 |
| Zhang, T | 1 |
| Duan, F | 1 |
| Wu, K | 1 |
| Yang, S | 1 |
| Xu, K | 1 |
| Jiang, X | 1 |
| Sun, X | 1 |
| Baheerathan, A | 1 |
| Pitceathly, RD | 1 |
| Curtis, C | 1 |
| Davies, NW | 1 |
| Ikawa, M | 1 |
| Okazawa, H | 1 |
| Yoneda, M | 1 |
| Liu, YJ | 2 |
| Liu, H | 1 |
| Wang, SB | 1 |
| Xiao, QM | 2 |
| Sun, AH | 1 |
| Li, YQ | 2 |
| Wang, WZ | 2 |
| Shibasaki, J | 1 |
| Niwa, T | 1 |
| Piedvache, A | 1 |
| Tomiyasu, M | 1 |
| Morisaki, N | 1 |
| Fujii, Y | 1 |
| Toyoshima, K | 1 |
| Aida, N | 1 |
| Gaddam, M | 1 |
| Velagapudi, RK | 1 |
| Abu Sitta, E | 1 |
| Kanzy, A | 1 |
| Potchen, MJ | 1 |
| Kampondeni, SD | 1 |
| Seydel, KB | 1 |
| Haacke, EM | 1 |
| Sinyangwe, SS | 1 |
| Mwenechanya, M | 1 |
| Glover, SJ | 1 |
| Milner, DA | 1 |
| Zeli, E | 1 |
| Hammond, CA | 1 |
| Utriainen, D | 1 |
| Lishimpi, K | 1 |
| Taylor, TE | 1 |
| Birbeck, GL | 1 |
| Short, JH | 1 |
| Sen, A | 1 |
| Soares, AA | 1 |
| de Oliveira, AL | 1 |
| Sá-Nakanishi, AB | 1 |
| Comar, JF | 1 |
| Rampazzo, AP | 1 |
| Vicentini, FA | 1 |
| Natali, MR | 1 |
| Gomes da Costa, SM | 1 |
| Bracht, A | 1 |
| Peralta, RM | 1 |
| Ma, GY | 1 |
| Zhao, LJ | 1 |
| Li, J | 1 |
| Wang, P | 1 |
| Caines, D | 1 |
| Sinclair, M | 1 |
| Wood, D | 1 |
| Valverde, A | 1 |
| Dyson, D | 1 |
| Gaitero, L | 1 |
| Nykamp, S | 1 |
| Xin, L | 1 |
| Lanz, B | 1 |
| Lei, H | 1 |
| Gruetter, R | 1 |
| Amaral, AU | 1 |
| Cecatto, C | 1 |
| Seminotti, B | 1 |
| Ribeiro, CA | 1 |
| Lagranha, VL | 1 |
| Pereira, CC | 1 |
| de Oliveira, FH | 1 |
| de Souza, DG | 1 |
| Goodman, S | 1 |
| Woontner, M | 1 |
| Wajner, M | 1 |
| Karkovska, M | 1 |
| Smutok, O | 1 |
| Gonchar, M | 1 |
| Uluc, K | 1 |
| Baskan, O | 1 |
| Yildirim, KA | 1 |
| Ozsahin, S | 1 |
| Koseoglu, M | 1 |
| Isak, B | 1 |
| Scheper, GC | 1 |
| Gunal, DI | 1 |
| van der Knaap, MS | 3 |
| Marcoux, J | 1 |
| McArthur, DA | 1 |
| Miller, C | 1 |
| Glenn, TC | 1 |
| Villablanca, P | 1 |
| Martin, NA | 1 |
| Hovda, DA | 1 |
| Alger, JR | 2 |
| Vespa, PM | 1 |
| Nagel, A | 1 |
| Graetz, D | 1 |
| Schink, T | 1 |
| Frieler, K | 1 |
| Sakowitz, O | 1 |
| Vajkoczy, P | 1 |
| Sarrafzadeh, A | 1 |
| Noda, K | 1 |
| Tanikawa, R | 1 |
| Sugimura, T | 1 |
| Kawasaki, K | 1 |
| Kimura, T | 1 |
| Izumi, N | 1 |
| Hashimoto, M | 1 |
| Lin, YW | 1 |
| Yu, CY | 1 |
| Girard, N | 1 |
| Htyte, N | 1 |
| White, L | 1 |
| Sandhu, G | 1 |
| Jones, J | 1 |
| Meisels, I | 1 |
| Joardar, S | 1 |
| Das, S | 1 |
| Chatterjee, R | 1 |
| Guha, G | 1 |
| Hasmi, MA | 1 |
| Takata, K | 1 |
| Kinoshita, M | 1 |
| Okuno, T | 1 |
| Moriya, M | 1 |
| Kohda, T | 1 |
| Honorat, JA | 1 |
| Sugimoto, T | 1 |
| Kumanogoh, A | 1 |
| Kayama, H | 1 |
| Takeda, K | 1 |
| Sakoda, S | 1 |
| Nakatsuji, Y | 1 |
| Danhier, F | 1 |
| Ansorena, E | 1 |
| Silva, JM | 1 |
| Coco, R | 1 |
| Le Breton, A | 1 |
| Préat, V | 1 |
| Miyaji, Y | 1 |
| Miyasaki, H | 1 |
| Ning, Z | 1 |
| Watanabe, D | 1 |
| Suzuki, Y | 1 |
| Kuroiwa, Y | 1 |
| Terek, D | 1 |
| Koroglu, O | 1 |
| Yalaz, M | 1 |
| Gokben, S | 1 |
| Calli, C | 1 |
| Coker, M | 1 |
| Kultursay, N | 1 |
| Arefyeva, IA | 1 |
| Semenova, JB | 1 |
| Zubairaev, MS | 1 |
| Kondrasheva, EA | 1 |
| Moshkin, AV | 1 |
| Frøen, JF | 1 |
| Amerio, G | 1 |
| Stray-Pedersen, B | 1 |
| Saugstad, OD | 1 |
| van der Voorn, P | 1 |
| Barkhof, F | 1 |
| Van Coster, R | 1 |
| Krägeloh-Mann, I | 1 |
| Feigenbaum, A | 1 |
| Blaser, S | 1 |
| Vles, JS | 1 |
| Rieckmann, P | 1 |
| Pouwels, PJ | 1 |
| Baik, HM | 1 |
| Choe, BY | 1 |
| Son, BC | 1 |
| Kim, MC | 1 |
| Kim, EN | 1 |
| Lee, HK | 1 |
| Suh, TS | 1 |
| ALTSCHULE, MD | 2 |
| HENNEMAN, DH | 1 |
| HOLLIDAY, P | 1 |
| GONCZ, RM | 1 |
| HEYCK, H | 1 |
| PERRIN, GM | 1 |
| HOLLIDAY, PD | 1 |
| KUBO, T | 1 |
| Horstmann, M | 1 |
| Neumaier-Probst, E | 1 |
| Lukacs, Z | 1 |
| Steinfeld, R | 1 |
| Ullrich, K | 1 |
| Kohlschütter, A | 1 |
| Nagae-Poetscher, LM | 1 |
| Bibat, G | 1 |
| Philippart, M | 2 |
| Rosemberg, S | 1 |
| Fatemi, A | 1 |
| Lacerda, MT | 1 |
| Costa, MO | 1 |
| Kok, F | 1 |
| Costa Leite, C | 1 |
| Horská, A | 1 |
| Barker, PB | 1 |
| Naidu, S | 1 |
| Grünewald, S | 1 |
| Champion, MP | 1 |
| Leonard, JV | 1 |
| Schaper, J | 1 |
| Morris, AA | 1 |
| Janes, SE | 1 |
| Santosh, B | 1 |
| Thomas, D | 1 |
| Vyas, H | 1 |
| Tsai, HM | 1 |
| Gao, CJ | 1 |
| Li, WX | 1 |
| Lin, MT | 1 |
| Niu, KC | 1 |
| van Hulst, RA | 1 |
| Drenthen, J | 1 |
| Haitsma, JJ | 1 |
| Lameris, TW | 1 |
| Visser, GH | 1 |
| Klein, J | 1 |
| Lachmann, B | 1 |
| Roerick, O | 1 |
| Seitz, T | 1 |
| Mauser-Weber, P | 1 |
| Palmaers, T | 1 |
| Weyand, M | 1 |
| Cesnjevar, R | 1 |
| Lange, T | 1 |
| Dydak, U | 1 |
| Roberts, TP | 1 |
| Rowley, HA | 1 |
| Bjeljac, M | 1 |
| Boesiger, P | 1 |
| Petzold, GC | 1 |
| Bohner, G | 1 |
| Klingebiel, R | 1 |
| Amberger, N | 1 |
| Zschenderlein, R | 1 |
| Huisman, TA | 1 |
| Klein, A | 1 |
| Werner, B | 1 |
| Straube, T | 1 |
| Boltshauser, E | 1 |
| Di Costanzo, A | 1 |
| Trojsi, F | 1 |
| Tosetti, M | 1 |
| Schirmer, T | 2 |
| Lechner, SM | 1 |
| Popolizio, T | 1 |
| Scarabino, T | 1 |
| Labauge, P | 1 |
| Roullet, E | 1 |
| Boespflug-Tanguy, O | 1 |
| Nicoli, F | 1 |
| Le Fur, Y | 1 |
| Cozzone, PJ | 1 |
| Ducreux, D | 1 |
| Rodriguez, D | 1 |
| Basheer, SN | 1 |
| Waters, PJ | 1 |
| Lam, CW | 1 |
| Acquaviva-Bourdain, C | 1 |
| Hendson, G | 1 |
| Poskitt, K | 1 |
| Hukin, J | 1 |
| Zupan Simunek, V | 1 |
| White, NJ | 1 |
| Warrell, DA | 1 |
| Chanthavanich, P | 1 |
| Looareesuwan, S | 1 |
| Warrell, MJ | 1 |
| Krishna, S | 1 |
| Williamson, DH | 1 |
| Turner, RC | 1 |
| Uziel, G | 1 |
| Bottacchi, E | 1 |
| Moschen, G | 1 |
| Giovanardi-Rossi, P | 1 |
| Cardace, G | 1 |
| Di Donato, S | 1 |
| Mandal, BK | 1 |
| Dunbar, EM | 1 |
| Hooper, J | 1 |
| Parker, L | 1 |
| Hansen, TL | 1 |
| Christensen, E | 1 |
| Brandt, NJ | 1 |
| Poptani, H | 1 |
| Gupta, RK | 1 |
| Roy, R | 1 |
| Pandey, R | 1 |
| Jain, VK | 1 |
| Chhabra, DK | 1 |
| Dotti, MT | 1 |
| Manneschi, L | 1 |
| Federico, A | 1 |
| Tedeschi, G | 1 |
| Schiffmann, R | 1 |
| Barton, NW | 1 |
| Shih, HH | 1 |
| Gospe, SM | 1 |
| Brady, RO | 1 |
| Di Chiro, G | 1 |
| Siciliano, G | 1 |
| Rossi, B | 1 |
| Martini, A | 1 |
| Angelini, C | 1 |
| Martinuzzi, A | 1 |
| Lodi, R | 1 |
| Zaniol, P | 1 |
| Barbiroli, B | 1 |
| Muratorio, A | 1 |
| Romero, IA | 1 |
| Lister, T | 1 |
| Richards, HK | 1 |
| Seville, MP | 1 |
| Wylie, SP | 1 |
| Ray, DE | 1 |
| Maran, A | 1 |
| Cranston, I | 1 |
| Lomas, J | 1 |
| Macdonald, I | 1 |
| Amiel, SA | 1 |
| Erecińska, M | 1 |
| Nelson, D | 1 |
| Hiraoka, A | 1 |
| Akai, J | 1 |
| Tominaga, I | 1 |
| Hattori, M | 1 |
| Sasaki, H | 1 |
| Arato, T | 1 |
| Hingorani, AD | 1 |
| Macdougall, IC | 1 |
| Browne, M | 1 |
| Walker, RW | 1 |
| Tomson, CR | 1 |
| Holshouser, BA | 1 |
| Ashwal, S | 1 |
| Luh, GY | 1 |
| Shu, S | 1 |
| Kahlon, S | 1 |
| Auld, KL | 1 |
| Tomasi, LG | 1 |
| Perkin, RM | 1 |
| Hinshaw, DB | 1 |
| Wakulicz-Deja, A | 1 |
| Paszek, P | 1 |
| Chang, KH | 1 |
| Song, IC | 1 |
| Kim, SH | 1 |
| Han, MH | 1 |
| Kim, HD | 1 |
| Seong, SO | 1 |
| Jung, HW | 1 |
| Han, MC | 1 |
| Ohki, S | 1 |
| Togari, H | 1 |
| Sobajima, H | 1 |
| Fujimoto, S | 1 |
| Kobayashi, M | 1 |
| Hyodo, J | 1 |
| Robertson, NJ | 1 |
| Cox, IJ | 1 |
| Cowan, FM | 1 |
| Counsell, SJ | 1 |
| Azzopardi, D | 1 |
| Edwards, AD | 1 |
| Kriegstein, AR | 1 |
| Shungu, DC | 1 |
| Millar, WS | 1 |
| Armitage, BA | 1 |
| Brust, JC | 1 |
| Chillrud, S | 1 |
| Goldman, J | 1 |
| Lynch, T | 1 |
| Harada, M | 1 |
| Hisaoka, S | 1 |
| Mori, K | 1 |
| Yoneda, K | 1 |
| Noda, S | 1 |
| Nishitani, H | 1 |
| Wilken, B | 1 |
| Dechent, P | 1 |
| Herms, J | 1 |
| Maxton, C | 1 |
| Markakis, E | 1 |
| Hanefeld, F | 1 |
| Frahm, J | 2 |
| Spencer, JA | 1 |
| Paterson-Brown, S | 1 |
| Brocklehurst, P | 1 |
| Blüml, S | 1 |
| Moreno, A | 1 |
| Hwang, JH | 1 |
| Ross, BD | 1 |
| Burtscher, IM | 1 |
| Holtås, S | 1 |
| Park, WS | 1 |
| Chang, YS | 1 |
| Lee, M | 1 |
| Auer, DP | 1 |
| Gössl, C | 1 |
| Czisch, M | 1 |
| Marszał, E | 1 |
| Wojaczyńska-Stanek, K | 1 |
| Pietruszewski, J | 1 |
| Emich-Widera, E | 1 |
| Bielińska-Bujniewicz, E | 1 |
| Bosman, DK | 1 |
| Deutz, NE | 1 |
| De Graaf, AA | 1 |
| vd Hulst, RW | 1 |
| Van Eijk, HM | 1 |
| Bovée, WM | 1 |
| Maas, MA | 1 |
| Jörning, GG | 1 |
| Chamuleau, RA | 1 |
| Robinson, BH | 1 |
| Glerum, DM | 1 |
| Chow, W | 1 |
| Petrova-Benedict, R | 1 |
| Lightowlers, R | 1 |
| Capaldi, R | 1 |
| Andersen, NE | 1 |
| Gyring, J | 1 |
| Hansen, AJ | 1 |
| Laursen, H | 1 |
| Siesjö, BK | 1 |
| Mizuno, Y | 1 |
| Ishiguro, K | 1 |
| Okamoto, K | 1 |
| Morimatsu, M | 1 |
| Hirai, S | 1 |
| Bruhn, H | 1 |
| Gyngell, ML | 1 |
| Merboldt, KD | 1 |
| Hänicke, W | 1 |
| Sauter, R | 1 |
| Hamburger, C | 1 |
| Scully, TB | 1 |
| Kraft, SC | 1 |
| Carr, WC | 1 |
| Harig, JM | 1 |
| Khan, NA | 1 |
| Guevara, P | 1 |
| Sotelo, J | 1 |
| Werneck, LC | 1 |
| Abdalla, H | 1 |
| Lohr, A | 1 |
| Yokochi, K | 1 |
| Tatsumi, C | 1 |
| Takahashi, M | 1 |
| Yorifuji, S | 1 |
| Nishikawa, Y | 1 |
| Kitaguchi, M | 1 |
| Hashimoto, S | 1 |
| Tarui, S | 1 |
| Al-Mateen, M | 1 |
| Shields, WD | 1 |
| Thurn, JR | 1 |
| Pierpont, GL | 1 |
| Ludvigsen, CW | 1 |
| Eckfeldt, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819] | 256 participants (Anticipated) | Observational | 2021-01-02 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for lactic acid and Brain Diseases
| Article | Year |
|---|---|
The role of SLC transporters for brain health and disease.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain; Brain Diseases; Humans; Lactic Acid; Membrane Trans | 2021 |
Lactate and Lactylation in the Brain: Current Progress and Perspectives.
Topics: Brain; Brain Diseases; Energy Metabolism; Glycolysis; Humans; Lactic Acid | 2023 |
CSF lactate.
Topics: Adult; Biomarkers; Brain Diseases; Central Nervous System Infections; Enterovirus; Female; Humans; L | 2020 |
Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders.
Topics: Acidosis, Lactic; Brain Diseases; Electron Transport; Fatty Acids; Glucose; Humans; Lactic Acid; Mag | 2021 |
[Magnetic resonance spectroscopy for cerebral imaging].
Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea | 2010 |
PLGA-based nanoparticles: an overview of biomedical applications.
Topics: Animals; Bacterial Infections; Brain Diseases; Cardiovascular Diseases; Drug Delivery Systems; Human | 2012 |
Proton MR spectroscopy of the brain at 3 T: an update.
Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Cortex; Choline; Creatine | 2007 |
[Definition of intrapartum asphyxia and effects on outcome].
Topics: Acidosis; Apgar Score; Biomarkers; Brain Diseases; Cerebral Palsy; Female; Fetal Blood; Fetal Hypoxi | 2008 |
Proton MR spectroscopy in clinical routine.
Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Humans; Lactic Acid; Magnetic Resonance Spectrosco | 2001 |
2 trials available for lactic acid and Brain Diseases
| Article | Year |
|---|---|
Protection by lactate of cerebral function during hypoglycaemia.
Topics: Adult; Blood Chemical Analysis; Brain; Brain Diseases; Cognition; Hormones; Humans; Hypoglycemia; La | 1994 |
Diagnose progressive encephalopathy applying the rough set theory.
Topics: Adolescent; Biopsy; Brain Diseases; Child; Child, Preschool; Decision Support Techniques; Diagnosis, | 1997 |
78 other studies available for lactic acid and Brain Diseases
| Article | Year |
|---|---|
Lower Availability of Mitochondrial Complex I in Anterior Cingulate Cortex in Autism: A Positron Emission Tomography Study.
Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Brain; Brain Diseases; Case-Control Studies; Ele | 2023 |
[Correlation between early eeg dual-frequency index monitoring combined with lactic acid clearance rate and delayed encephalopathy with acute severe carbon monoxide poisoning].
Topics: Brain Diseases; Carbon Monoxide Poisoning; Humans; Lactic Acid; Prognosis; Retrospective Studies | 2021 |
Comparison of Predictive Values of Magnetic Resonance Biomarkers Based on Scan Timing in Neonatal Encephalopathy Following Therapeutic Hypothermia.
Topics: Aspartic Acid; Biomarkers; Brain Diseases; Dipeptides; Gray Matter; Humans; Hypothermia, Induced; In | 2021 |
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning?
Topics: Acid-Base Equilibrium; Acidosis; Anticonvulsants; Brain Diseases; Calcium Oxalate; Cognitive Dysfunc | 2017 |
1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria.
Topics: Adolescent; Blood Glucose; Brain Diseases; Child; Child, Preschool; Female; Gadolinium; Humans; Infa | 2018 |
62-Year-Old Man With Encephalopathy and Fatigue After Allogeneic Bone Marrow Transplant.
Topics: Bone Marrow Transplantation; Brain Diseases; Consciousness Disorders; Cytomegalovirus Infections; Ep | 2018 |
Effects of an Agaricus blazei aqueous extract pretreatment on paracetamol-induced brain and liver injury in rats.
Topics: Acetaminophen; Administration, Oral; Agaricus; Alanine; Animals; Antioxidants; Biomarkers; Brain; Br | 2013 |
[The relationship between lactate clearance rate and delayed encephalopathy after acute carbon monoxide poisoning].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Diseases; Carbon Monoxide Poisoning; Child; Female | 2013 |
Evaluation of cerebrospinal fluid lactate and plasma lactate concentrations in anesthetized dogs with and without intracranial disease.
Topics: Animals; Brain Diseases; Case-Control Studies; Dog Diseases; Dogs; Female; Lactic Acid; Male; Prospe | 2013 |
Assessment of metabolic fluxes in the mouse brain in vivo using 1H-[13C] NMR spectroscopy at 14.1 Tesla.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Brain Diseases; Carbon Isotopes; Glucose; Humans; Lact | 2015 |
Experimental evidence that bioenergetics disruption is not mainly involved in the brain injury of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases; Brain Diseases, Metabolic; Cerebral C | 2015 |
Laboratory Prototype of Bioreactor for Oxidation of Toxic D-Lactate Using Yeast Cells Overproducing D-Lactate Cytochrome c Oxidoreductase.
Topics: Bioreactors; Brain Diseases; Fermentation; Foodborne Diseases; Glucose; Lactate Dehydrogenases; Lact | 2016 |
Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings.
Topics: Adult; Aspartate-tRNA Ligase; Aspartic Acid; Brain Diseases; Brain Stem; Creatine; Humans; Lactic Ac | 2008 |
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Stud | 2008 |
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutam | 2009 |
Use of bioabsorbable plates for cranial fixation.
Topics: Absorbable Implants; Biocompatible Materials; Bone Plates; Bone Screws; Brain Diseases; Craniotomy; | 2009 |
Reversible focal splenium lesion--MRS study of a different etiology.
Topics: Adult; Aspartic Acid; Brain Diseases; Brain Mapping; Corpus Callosum; Diffusion Magnetic Resonance I | 2009 |
An extreme and life-threatening case of recurrent D-lactate encephalopathy.
Topics: Acidosis, Lactic; Brain Diseases; Humans; Kidney Failure, Chronic; Lactic Acid; Male; Middle Aged; R | 2011 |
Unilateral basal-ganglia involvement likely due to valproate-induced hyperammonemic encephalopathy.
Topics: Anticonvulsants; Basal Ganglia; Brain Diseases; Child, Preschool; Diffusion Magnetic Resonance Imagi | 2012 |
The lactic acid bacterium Pediococcus acidilactici suppresses autoimmune encephalomyelitis by inducing IL-10-producing regulatory T cells.
Topics: Administration, Oral; Animals; Brain Diseases; Encephalitis; Female; Hashimoto Disease; Interleukin- | 2011 |
[A 68 year-old man presenting ideomotor apraxia and incomplete Gerstmann syndrome with multiple cystic lesions in the left hemisphere].
Topics: Aged; Apraxia, Ideomotor; Brain Diseases; Cerebrovascular Circulation; Cysts; Electroencephalography | 2012 |
Diagnostic tools of early brain disturbances in an asymptomatic neonate with maple syrup urine disease.
Topics: Aspartic Acid; Brain Diseases; Brain Waves; Consanguinity; Developmental Disabilities; Diet; Diet, C | 2013 |
Analysis of fluid in craniopharyngioma-related cysts in children: proteins, lactate and pH.
Topics: Adolescent; Albumins; Blood-Brain Barrier; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; | 2002 |
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain Diseases; Corpus Striatum; Endotoxins; Escherichia | 2002 |
A new leukoencephalopathy with brainstem and spinal cord involvement and high lactate.
Topics: Adolescent; Adult; Brain Diseases; Brain Stem; Child; Female; Humans; Lactic Acid; Magnetic Resonanc | 2003 |
Feasibility of proton chemical shift imaging with a stereotactic headframe.
Topics: Adult; Biopsy, Needle; Brain; Brain Diseases; Choline; Creatine; Feasibility Studies; Female; Humans | 2003 |
Carbohydrate metabolism in brain disease. VI. Lactate metabolism after infusion of sodium d-lactate in manic-depressive and schizophrenic psychoses.
Topics: Bipolar Disorder; Brain Diseases; Carbohydrate Metabolism; Humans; Lactic Acid; Mental Disorders; Ps | 1956 |
[On the problem of cryptogenetic processes of brain atrophy: quantitative measurements of cerebral circulation and cerebral glucose, lactic acid and pyruvic acid metabolism].
Topics: Atrophy; Brain; Brain Diseases; Cerebrovascular Circulation; Glucose; Humans; Lactates; Lactic Acid; | 1961 |
Carbohydrate metabolism in brain disease. XIII. Effect of lactate infusion on blood keto-acid concentrations in schizophremic and manic-depressive psychoses.
Topics: Bipolar Disorder; Brain Diseases; Carbohydrate Metabolism; Humans; Keto Acids; Lactates; Lactic Acid | 1960 |
[Experimental and clinical studies of the carbohydrate metabolism in injured brain with special reference to the glycogen and lactate contents].
Topics: Brain; Brain Diseases; Carbohydrate Metabolism; Glycogen; Humans; Lactates; Lactic Acid | 1961 |
Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion.
Topics: Brain Diseases; Choline Deficiency; Humans; Infant; Lactic Acid; Magnetic Resonance Spectroscopy; Ma | 2003 |
Leukoencephalopathy, cerebral calcifications, and cysts: new observations.
Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Calcinosis; Central Nervous System Cysts; Child; C | 2004 |
Biotinidase deficiency: a treatable leukoencephalopathy.
Topics: Biotinidase Deficiency; Brain; Brain Diseases; Follow-Up Studies; Humans; Infant; Lactic Acid; Male; | 2004 |
Hashimoto's encephalopathy: an unusual cause of seizures in the intensive care unit.
Topics: Adolescent; Autoantibodies; Brain Diseases; Cognition Disorders; Female; Glucocorticoids; Humans; In | 2004 |
Resuscitation from experimental heatstroke by hyperbaric oxygen therapy.
Topics: Animals; Biomarkers; Brain Diseases; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; H | 2005 |
Effects of hyperbaric treatment in cerebral air embolism on intracranial pressure, brain oxygenation, and brain glucose metabolism in the pig.
Topics: Animals; Brain; Brain Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Electroenc | 2005 |
Low-flow perfusion via the innominate artery during aortic arch operations provides only limited somatic circulatory support.
Topics: Acid-Base Imbalance; Animals; Animals, Newborn; Aorta, Thoracic; Body Temperature; Brachiocephalic T | 2006 |
Pitfalls in lactate measurements at 3T.
Topics: Brain Diseases; False Negative Reactions; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Phan | 2006 |
Adult onset leucoencephalopathy with brain stem and spinal cord involvement and normal lactate.
Topics: Adult; Age of Onset; Brain Chemistry; Brain Diseases; Brain Stem; Female; Gait Ataxia; Humans; Lacti | 2006 |
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion | 2006 |
Familial, adult onset form of leukoencephalopathy with brain stem and spinal cord involvement: inconstant high brain lactate and very slow disease progression.
Topics: Adult; Brain Chemistry; Brain Diseases; Brain Stem; Disease Progression; Family Health; Female; Huma | 2007 |
Isolated sulfite oxidase deficiency in the newborn: lactic acidaemia and leukoencephalopathy.
Topics: Acidosis, Lactic; Brain Diseases; Homocysteine; Humans; Infant, Newborn; Lactic Acid; Male; Sulfite | 2007 |
Severe hypoglycemia and hyperinsulinemia in falciparum malaria.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Brain Diseases; C-Peptide; Child; | 1983 |
Pyruvate-dehydrogenase complex in ataxic patients: enzyme deficiency in ataxic encephalopathy plus lactic acidosis and normal activity in Friedreich ataxia.
Topics: Acidosis; Adolescent; Ataxia; Brain Diseases; Fibroblasts; Friedreich Ataxia; Humans; Lactates; Lact | 1982 |
How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis?
Topics: Brain Diseases; Diagnosis, Differential; Humans; Lactates; Lactic Acid; Meningitis; Meningitis, Vira | 1983 |
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fi | 1982 |
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea | 1995 |
Mitochondrial enzyme deficiency in cerebrotendinous xanthomatosis.
Topics: Adult; Biopsy; Brain Diseases; Electron Transport; Female; Humans; Lactates; Lactic Acid; Mitochondr | 1995 |
Proton magnetic resonance spectroscopic imaging in childhood ataxia with diffuse central nervous system hypomyelination.
Topics: Aspartic Acid; Ataxia; Brain; Brain Diseases; Child, Preschool; Choline; Creatine; Female; Gaucher D | 1995 |
Myophosphorylase deficiency affects muscle mitochondrial respiration as shown by 31P-MR spectroscopy in a case with associated multifocal encephalopathy.
Topics: Adult; Aerobiosis; Brain Diseases; DNA; Electrocardiography; Energy Metabolism; Exercise; Glycogen; | 1995 |
Early metabolic changes during m-Dinitrobenzene neurotoxicity and the possible role of oxidative stress.
Topics: Animals; Animals, Newborn; Astrocytes; Blood-Brain Barrier; Brain; Brain Diseases; Cell Death; Cells | 1995 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Amin | 1994 |
Capillary zone electrophoretic determination of organic acids in cerebrospinal fluid from patients with central nervous system diseases.
Topics: Brain Diseases; Cerebral Infarction; Electrophoresis; Humans; Lactates; Lactic Acid; Meningitis, Bac | 1994 |
Successful treatment of acute D-lactate encephalopathy by haemodialysis.
Topics: Acute Disease; Adult; Brain Diseases; Female; Humans; Intestine, Small; Lactates; Lactic Acid; Posto | 1993 |
Proton MR spectroscopy after acute central nervous system injury: outcome prediction in neonates, infants, and children.
Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Brain Injuries; Child; Choline; Discriminant Analy | 1997 |
In vivo single-voxel proton MR spectroscopy in intracranial cystic masses.
Topics: Adult; Amino Acids; Brain Abscess; Brain Diseases; Brain Neoplasms; Cysticercosis; Cysts; Female; Ga | 1998 |
Lactate attenuates neuron specific enolase elevation in newborn rats.
Topics: Adenosine Triphosphate; Animals; Biomarkers; Brain; Brain Diseases; Hypoxia; Lactic Acid; Phosphopyr | 1999 |
Cerebral intracellular lactic alkalosis persisting months after neonatal encephalopathy measured by magnetic resonance spectroscopy.
Topics: Brain; Brain Diseases; Cytoplasm; Fetal Hypoxia; Humans; Infant; Infant, Newborn; Lactic Acid; Magne | 1999 |
Leukoencephalopathy and raised brain lactate from heroin vapor inhalation ("chasing the dragon")
Topics: Administration, Inhalation; Adult; Antioxidants; Biopsy; Brain; Brain Diseases; Female; Heroin; Huma | 1999 |
Differences in water diffusion and lactate production in two different types of postinfectious encephalopathy.
Topics: Body Water; Brain Chemistry; Brain Diseases; Child; Echo-Planar Imaging; Encephalomyelitis, Acute Di | 2000 |
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; | 2000 |
Fetal blood lactate concentration.
Topics: Brain Diseases; Fetal Blood; Humans; Lactic Acid; Osmolar Concentration | 2000 |
1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Canavan Disease; Carbon Isotopes; Chi | 2001 |
7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain Diseases; Cerebral Cortex; Cerebrospinal Fluid; Dise | 2001 |
Improved analysis of 1H-MR spectra in the presence of mobile lipids.
Topics: Alanine; Artifacts; Brain; Brain Diseases; Brain Neoplasms; Glioblastoma; Glioma; Humans; Image Enha | 2001 |
Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.
Topics: Adolescent; Brain Diseases; Case-Control Studies; Cerebrovascular Disorders; Child; Child, Preschool | 2002 |
Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation.
Topics: Acute Disease; Ammonia; Animals; Brain; Brain Diseases; Electroencephalography; Glutamates; Glutamic | 1990 |
The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia.
Topics: Acidosis, Lactic; Brain Diseases; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Fibroblasts; Hum | 1990 |
Brain acidosis in experimental pneumococcal meningitis.
Topics: Acidosis; Animals; Blood Glucose; Brain Diseases; Carbon Dioxide; Glucose; Humans; Hydrogen-Ion Conc | 1989 |
[A case of mitochondrial encephalomyopathy characterized by repeated stroke-like episodes].
Topics: Adult; Brain Diseases; Cerebrovascular Disorders; Electroencephalography; Epilepsies, Myoclonic; Hum | 1989 |
Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.
Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Cysts; | 1989 |
D-lactate-associated encephalopathy after massive small-bowel resection.
Topics: Acidosis, Lactic; Adolescent; Brain Diseases; Humans; Ileum; Intestinal Absorption; Isomerism; Jejun | 1989 |
Influence of in vitro lactic acidosis on central nervous system neurons.
Topics: Acidosis, Lactic; Brain Diseases; Cells, Cultured; Central Nervous System; Chromatin; Citrates; Citr | 1989 |
[MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes): report of a case].
Topics: Acidosis, Lactic; Brain Diseases; Cerebrovascular Disorders; Child; Electron Transport Complex IV; H | 1987 |
[Neurological approach to mitochondrial abnormalities].
Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Cytochrome-c Oxidase Deficiency; Female; Humans | 1987 |
Mitochondrial encephalomyopathy with sleep apnea.
Topics: Brain Diseases; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria; Muscles; Muscular Di | 1988 |
Rett syndrome. A commonly overlooked progressive encephalopathy in girls.
Topics: Adolescent; Adult; Ataxia; Basal Ganglia Diseases; Brain Diseases; Child; Child, Preschool; Dementia | 1986 |
D-lactate encephalopathy.
Topics: Acidosis; Adult; Brain Diseases; Female; Humans; Jejunoileal Bypass; Lactates; Lactic Acid; Male; Mi | 1985 |