lactic acid has been researched along with Bone Cancer in 28 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of lactic acid (LA) on the progression of bone metastasis from colorectal cancer (CRC) and its regulatory effects on primary CD115 (+) osteoclast (OC) precursors." | 8.02 | Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer. ( Gong, ZC; Kang, X; Liu, D; Liu, XL; Qian, J; Sheng, J; Wang, LT; Wang, W; Wu, HH; Wu, J; Xu, W; Ye, LJ; Zhang, YN; Zhao, J; Zheng, W, 2021) |
| "This bone targeted cabazitaxel nanocarrier system showed significant reduction in tumor burden, while at the same time maintaining bone structure integrity and reducing pain in the mouse tumor limb." | 7.85 | Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain. ( Gdowski, AS; Ranjan, A; Sarker, MR; Vishwanatha, JK, 2017) |
| " Present study examines the antitumor potential of paclitaxel (PTX) and etoposide (ETP)-loaded PLGA nanoparticles for the treatment of osteosarcoma." | 7.81 | Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma. ( Wang, B; Xu, M; Xu, SF; Yu, XC, 2015) |
| "In this study, ifosfamide-loaded poly (lactic-co-glycolic acid) (PLGA)-dextran polymeric nanoparticles (PD/IFS) was developed and studied its anticancer efficacy against multiple osteosarcoma cancer cells." | 7.81 | Ifosfamide-loaded poly (lactic-co-glycolic acid) PLGA-dextran polymeric nanoparticles to improve the antitumor efficacy in Osteosarcoma. ( Chen, B; Lin, XJ; Wang, LF; Yang, JZ; Zhang, YJ, 2015) |
| "In order to prepare a biomimetic nano-carrier which has inflammatory chemotaxis, homologous targeting and reduce immune clearance, for targeted chemotherapy of osteosarcoma, we fabricated the paclitaxel-loaded poly(lactic-co-glycolic) acid (PLGA) nanoparticles coated with 143B-RAW hybrid membrane (PTX-PLGA@[143B-RAW] NPs) and evaluate its anti-cancer efficacy in vitro and vivo." | 4.12 | Hybrid Cell Membrane-Functionalized Biomimetic Nanoparticles for Targeted Therapy of Osteosarcoma. ( Cai, JX; Li, YJ; Liu, JH; Qiu, XH; Wu, JY; Xiang, DX; Xu, P; Xu, WJ, 2022) |
| "To investigate the effect of lactic acid (LA) on the progression of bone metastasis from colorectal cancer (CRC) and its regulatory effects on primary CD115 (+) osteoclast (OC) precursors." | 4.02 | Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer. ( Gong, ZC; Kang, X; Liu, D; Liu, XL; Qian, J; Sheng, J; Wang, LT; Wang, W; Wu, HH; Wu, J; Xu, W; Ye, LJ; Zhang, YN; Zhao, J; Zheng, W, 2021) |
| "This bone targeted cabazitaxel nanocarrier system showed significant reduction in tumor burden, while at the same time maintaining bone structure integrity and reducing pain in the mouse tumor limb." | 3.85 | Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain. ( Gdowski, AS; Ranjan, A; Sarker, MR; Vishwanatha, JK, 2017) |
| " Present study examines the antitumor potential of paclitaxel (PTX) and etoposide (ETP)-loaded PLGA nanoparticles for the treatment of osteosarcoma." | 3.81 | Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma. ( Wang, B; Xu, M; Xu, SF; Yu, XC, 2015) |
| "In this study, ifosfamide-loaded poly (lactic-co-glycolic acid) (PLGA)-dextran polymeric nanoparticles (PD/IFS) was developed and studied its anticancer efficacy against multiple osteosarcoma cancer cells." | 3.81 | Ifosfamide-loaded poly (lactic-co-glycolic acid) PLGA-dextran polymeric nanoparticles to improve the antitumor efficacy in Osteosarcoma. ( Chen, B; Lin, XJ; Wang, LF; Yang, JZ; Zhang, YJ, 2015) |
| "Osteosarcoma is the most common primary malignant bone tumor in adolescents and children and prone to develop lung metastasis." | 1.91 | Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis. ( Gao, Y; Liu, Y; Sheng, G; Wu, H; Yang, Y, 2023) |
| "To provide novel strategies for future treatment of osteosarcoma, the properties of the scaffold, including its in vitro extended-release properties, the inhibition effects of ADM-PLGA-NHAC on the osteosarcoma MG63 cells, and its bone repair capacity, were investigated in vivo and in vitro." | 1.43 | Porous nano-hydroxyapatite/collagen scaffold containing drug-loaded ADM-PLGA microspheres for bone cancer treatment. ( Cai, BT; Cao, YL; Rong, ZJ; Wu, GF; Yang, LJ; Zhang, ZJ; Zhu, LX, 2016) |
| " Sustained release nanoparticles (NP) offer increased resistance to nuclease degradation, increased amounts of AS uptake, and the possibility of control in dosing and sustained duration of AS administration." | 1.36 | Biodistribution of antisense nanoparticles in mammary carcinoma rat model. ( Adwan, H; Berger, MR; Elazar, V; Golomb, G; Lifshitz-Shovali, R; Rohekar, K; Zepp, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 18 (64.29) | 24.3611 |
| 2020's | 8 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, JX | 1 |
| Liu, JH | 1 |
| Wu, JY | 1 |
| Li, YJ | 1 |
| Qiu, XH | 1 |
| Xu, WJ | 1 |
| Xu, P | 1 |
| Xiang, DX | 1 |
| Sheng, G | 1 |
| Gao, Y | 1 |
| Wu, H | 1 |
| Liu, Y | 2 |
| Yang, Y | 1 |
| Dakpé, S | 1 |
| Colin, E | 1 |
| Bettoni, J | 1 |
| Davrou, J | 1 |
| Diouf, M | 1 |
| Devauchelle, B | 1 |
| Testelin, S | 1 |
| Avnet, S | 2 |
| Lemma, S | 1 |
| Errani, C | 1 |
| Falzetti, L | 1 |
| Panza, E | 1 |
| Columbaro, M | 1 |
| Nanni, C | 1 |
| Baldini, N | 2 |
| Wan, J | 1 |
| Long, F | 1 |
| Tian, J | 1 |
| Zhang, C | 1 |
| Qian, J | 1 |
| Gong, ZC | 1 |
| Zhang, YN | 1 |
| Wu, HH | 1 |
| Zhao, J | 1 |
| Wang, LT | 1 |
| Ye, LJ | 1 |
| Liu, D | 1 |
| Wang, W | 1 |
| Kang, X | 1 |
| Sheng, J | 1 |
| Xu, W | 1 |
| Liu, XL | 1 |
| Wu, J | 2 |
| Zheng, W | 1 |
| Tan, W | 1 |
| Gao, C | 1 |
| Feng, P | 1 |
| Liu, Q | 1 |
| Liu, C | 1 |
| Wang, Z | 1 |
| Deng, Y | 1 |
| Shuai, C | 1 |
| Yu, B | 1 |
| Zhang, F | 1 |
| Liu, L | 1 |
| Liang, Y | 1 |
| Tang, X | 1 |
| Peng, Y | 1 |
| Cai, F | 1 |
| Zeng, D | 1 |
| Yuan, X | 1 |
| Li, J | 1 |
| Guo, Y | 1 |
| Lv, B | 1 |
| Wang, M | 1 |
| Liao, Q | 1 |
| Lv, XB | 1 |
| Gdowski, AS | 1 |
| Ranjan, A | 1 |
| Sarker, MR | 1 |
| Vishwanatha, JK | 2 |
| Patricio, BF | 1 |
| Albernaz, Mde S | 1 |
| Sarcinelli, MA | 1 |
| de Carvalho, SM | 1 |
| Santos-Oliveira, R | 1 |
| Weissmüller, G | 1 |
| Swami, A | 1 |
| Reagan, MR | 1 |
| Basto, P | 1 |
| Mishima, Y | 1 |
| Kamaly, N | 1 |
| Glavey, S | 1 |
| Zhang, S | 1 |
| Moschetta, M | 1 |
| Seevaratnam, D | 1 |
| Zhang, Y | 1 |
| Liu, J | 1 |
| Memarzadeh, M | 1 |
| Manier, S | 1 |
| Shi, J | 1 |
| Bertrand, N | 1 |
| Lu, ZN | 1 |
| Nagano, K | 1 |
| Baron, R | 1 |
| Sacco, A | 1 |
| Roccaro, AM | 1 |
| Farokhzad, OC | 1 |
| Ghobrial, IM | 1 |
| Yogev, O | 1 |
| Lagos, D | 1 |
| Enver, T | 1 |
| Boshoff, C | 1 |
| Yoneda, T | 1 |
| Hiasa, M | 1 |
| Nagata, Y | 1 |
| Okui, T | 1 |
| White, F | 1 |
| Wang, B | 1 |
| Yu, XC | 1 |
| Xu, SF | 1 |
| Xu, M | 1 |
| Stolzoff, M | 1 |
| Webster, TJ | 1 |
| Chen, B | 1 |
| Yang, JZ | 1 |
| Wang, LF | 1 |
| Zhang, YJ | 1 |
| Lin, XJ | 1 |
| Altındal, DÇ | 1 |
| Gümüşderelioğlu, M | 1 |
| Liu, P | 1 |
| Sun, L | 1 |
| Zhou, DS | 1 |
| Zhang, P | 1 |
| Wang, YH | 1 |
| Li, D | 1 |
| Li, QH | 1 |
| Feng, RJ | 1 |
| Rong, ZJ | 1 |
| Yang, LJ | 1 |
| Cai, BT | 1 |
| Zhu, LX | 1 |
| Cao, YL | 1 |
| Wu, GF | 1 |
| Zhang, ZJ | 1 |
| Jiang, L | 2 |
| Xiong, C | 1 |
| Su, S | 1 |
| Ray, S | 1 |
| Saha, S | 1 |
| Sa, B | 1 |
| Chakraborty, J | 1 |
| Elazar, V | 2 |
| Adwan, H | 2 |
| Bäuerle, T | 1 |
| Rohekar, K | 2 |
| Golomb, G | 2 |
| Berger, MR | 2 |
| Zepp, M | 1 |
| Lifshitz-Shovali, R | 1 |
| Kai, H | 1 |
| Wang, X | 2 |
| Madhukar, KS | 1 |
| Qin, L | 1 |
| Yan, Y | 1 |
| Zhang, R | 1 |
| Cenni, E | 1 |
| Granchi, D | 1 |
| Fotia, C | 1 |
| Salerno, M | 1 |
| Micieli, D | 1 |
| Sarpietro, MG | 1 |
| Pignatello, R | 1 |
| Castelli, F | 1 |
| Ramanlal Chaudhari, K | 1 |
| Kumar, A | 1 |
| Megraj Khandelwal, VK | 1 |
| Ukawala, M | 1 |
| Manjappa, AS | 1 |
| Mishra, AK | 1 |
| Monkkonen, J | 1 |
| Ramachandra Murthy, RS | 1 |
| Thamake, SI | 1 |
| Raut, SL | 1 |
| Gryczynski, Z | 1 |
| Ranjan, AP | 1 |
| Hillmann, A | 1 |
| Weist, R | 1 |
| Fromme, A | 1 |
| Völker, K | 1 |
| Rosenbaum, D | 1 |
1 review available for lactic acid and Bone Cancer
| Article | Year |
|---|---|
Contribution of acidic extracellular microenvironment of cancer-colonized bone to bone pain.
Topics: Acid Sensing Ion Channels; Analgesics; Bone and Bones; Bone Neoplasms; Bone Resorption; Gene Express | 2015 |
27 other studies available for lactic acid and Bone Cancer
| Article | Year |
|---|---|
Hybrid Cell Membrane-Functionalized Biomimetic Nanoparticles for Targeted Therapy of Osteosarcoma.
Topics: Animals; Biomimetics; Bone Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Carriers; Humans; Lactic | 2022 |
Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis.
Topics: Bone Neoplasms; Glucose; Humans; Lactic Acid; Monocarboxylic Acid Transporters; Neoplastic Cells, Ci | 2023 |
Intraosseous microdialysis for bone free flap monitoring in head and neck reconstructive surgery: A prospective pilot study.
Topics: Adolescent; Adult; Aged; Bone Neoplasms; Facial Bones; Female; Fibula; Free Tissue Flaps; Glucose; H | 2020 |
Benign albeit glycolytic: MCT4 expression and lactate release in giant cell tumour of bone.
Topics: Bone Neoplasms; Giant Cell Tumor of Bone; Glycolysis; Humans; Lactic Acid; Membrane Transport Protei | 2020 |
circPVT1 promotes osteosarcoma glycolysis and metastasis by sponging miR-423-5p to activate Wnt5a/Ror2 signaling.
Topics: 3' Untranslated Regions; A549 Cells; Animals; Bone Neoplasms; Cell Movement; Cell Proliferation; Glu | 2021 |
Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer.
Topics: Animals; Bone Neoplasms; Cadherins; CD4-Positive T-Lymphocytes; Cell Adhesion; Cell Differentiation; | 2021 |
Dual-functional scaffolds of poly(L-lactic acid)/nanohydroxyapatite encapsulated with metformin: Simultaneous enhancement of bone repair and bone tumor inhibition.
Topics: Bone Neoplasms; Durapatite; Humans; Lactic Acid; Metformin; Osteogenesis; Polyesters; Tissue Enginee | 2021 |
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Computational Biology; Database | 2021 |
Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain.
Topics: Animals; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Dip | 2017 |
Development of novel nanoparticle for bone cancer.
Topics: Animals; Bone Neoplasms; Injections; Lactic Acid; Nanoparticles; Organophosphorus Compounds; Polyest | 2014 |
Engineered nanomedicine for myeloma and bone microenvironment targeting.
Topics: Alendronate; Animals; Antineoplastic Agents; Bone Neoplasms; Boronic Acids; Bortezomib; Cell Line, T | 2014 |
Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells.
Topics: Aerobiosis; Blotting, Western; Bone Neoplasms; Cell Proliferation; Endothelial Cells; Endothelium, V | 2014 |
Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tu | 2015 |
Reducing bone cancer cell functions using selenium nanocomposites.
Topics: Bone Neoplasms; Cell Line, Tumor; Coated Materials, Biocompatible; Humans; Lactic Acid; Nanocomposit | 2016 |
Ifosfamide-loaded poly (lactic-co-glycolic acid) PLGA-dextran polymeric nanoparticles to improve the antitumor efficacy in Osteosarcoma.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Bone Neoplasms; Caspase 3; Cell Line, Tumor; | 2015 |
Melatonin releasing PLGA micro/nanoparticles and their effect on osteosarcoma cells.
Topics: Bone Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Humans; Lactic Acid; Melatonin; Nanop | 2016 |
Development of Alendronate-conjugated Poly (lactic-co-glycolic acid)-Dextran Nanoparticles for Active Targeting of Cisplatin in Osteosarcoma.
Topics: Alendronate; Animals; Bone Neoplasms; Cell Line, Tumor; Cisplatin; Dextrans; Drug Carriers; Humans; | 2015 |
Porous nano-hydroxyapatite/collagen scaffold containing drug-loaded ADM-PLGA microspheres for bone cancer treatment.
Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Collagen; Doxorubicin; Durap | 2016 |
Improving the degradation behavior and in vitro biological property of nano-hydroxyapatite surface- grafted with the assist of citric acid.
Topics: Biocompatible Materials; Bone Neoplasms; Cell Adhesion; Cell Proliferation; Citric Acid; Durapatite; | 2016 |
In vivo pharmacological evaluation and efficacy study of methotrexate-encapsulated polymer-coated layered double hydroxide nanoparticles for possible application in the treatment of osteosarcoma.
Topics: Aluminum; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Female; Humans | 2017 |
Sustained delivery and efficacy of polymeric nanoparticles containing osteopontin and bone sialoprotein antisenses in rats with breast cancer bone metastasis.
Topics: Animals; Bone Neoplasms; Breast Neoplasms; Drug Delivery Systems; Female; Humans; Integrin-Binding S | 2010 |
Biodistribution of antisense nanoparticles in mammary carcinoma rat model.
Topics: Animals; Antineoplastic Agents; Antisense Elements (Genetics); Bone Neoplasms; Carcinoma; Cell Line, | 2010 |
Fabrication of a two-level tumor bone repair biomaterial based on a rapid prototyping technique.
Topics: Absorption; Bone Neoplasms; Bone Substitutes; Calcium Phosphates; Chitosan; Computer-Aided Design; G | 2009 |
The effect of poly(d,l-lactide-co-glycolide)-alendronate conjugate nanoparticles on human osteoclast precursors.
Topics: Actins; Alendronate; Apoptosis; Bone Density Conservation Agents; Bone Neoplasms; Cells, Cultured; C | 2012 |
Bone metastasis targeting: a novel approach to reach bone using Zoledronate anchored PLGA nanoparticle as carrier system loaded with Docetaxel.
Topics: Animals; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Cell Line; Cell Li | 2012 |
Alendronate coated poly-lactic-co-glycolic acid (PLGA) nanoparticles for active targeting of metastatic breast cancer.
Topics: Alendronate; Animals; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Boronic Acids; Bortezom | 2012 |
Sports activities and endurance capacity of bone tumor patients after rotationplasty.
Topics: Adolescent; Adult; Bone Neoplasms; Case-Control Studies; Child; Cross-Sectional Studies; Exercise Te | 2007 |