lactic acid has been researched along with Blood Poisoning in 606 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study assessed the ability of mid-regional proadrenomedullin (MR-proADM) in comparison to conventional biomarkers (procalcitonin (PCT), lactate, C-reactive protein) and clinical scores to identify disease severity in patients with sepsis." | 9.27 | The use of mid-regional proadrenomedullin to identify disease severity and treatment response to sepsis - a secondary analysis of a large randomised controlled trial. ( Bloos, F; Briegel, J; Brunkhorst, FM; Elke, G; Jaschinski, U; Kluge, S; Loeffler, M; Meybohm, P; Moerer, O; Nierhaus, A; Reinhart, K; Weyland, A; Wilson, DC, 2018) |
| " However, no study has yet discovered which factor is most important for mortality in severe sepsis patients with lactic acidosis." | 9.20 | Lactate Clearance and Vasopressor Seem to Be Predictors for Mortality in Severe Sepsis Patients with Lactic Acidosis Supplementing Sodium Bicarbonate: A Retrospective Analysis. ( An, WS; Jeong, HJ; Kim, EB; Kim, SE; Lee, SM; Son, YK, 2015) |
| "Levosimendan and dobutamine are extensively used to treat sepsis-associated cardiovascular failure in ICU." | 9.12 | Levosimendan versus dobutamine for sepsis-induced cardiac dysfunction: a systematic review and meta-analysis. ( Chen, J; Chen, WT; Lei, YY; Lin, XF; Liu, DH; Liu, YY; Ning, YL; Xian, SX; Yang, ZQ, 2021) |
| " With serum lactate values > 10 mmol/l 80 % of the patients die in intensive care, and if the severe lactic acidosis persists for 48 hours, all patients die." | 8.98 | [Lactic acidosis - update 2018]. ( de Heer, G; Fuhrmann, V; Jarczak, D; Kluge, S; Nierhaus, A, 2018) |
| "In our data, preadmission metformin use is associated with a significantly larger decrease in lactate after admission with sepsis or septic shock and with reduced mortality in septic shock." | 8.31 | New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study. ( De Decker, K; De Neve, N; Tackaert, T; Van Moorter, N; Van Vlem, B, 2023) |
| "To explore the predictive value of serum sodium variability within 72 hours, lactic acid (Lac), sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation II (APACHE II) in predicting the 28-day prognosis of sepsis patients." | 8.31 | [Prognostic value of serum sodium variability within 72 hours and lactic acid combined with severity score in patients with sepsis]. ( Chi, H; Hu, D; Li, Q; Lian, Z; Wang, H; Zhang, C; Zhang, S, 2023) |
| "Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate the effect of papaverine on RAGE associated NF-κB pathway by determining the level of soluble RAGE (sRAGE) and HMGB1, and to support this hypothesis by evaluating inflammatory biochemical, oxidative stress markers, Hounsfield unit (HU) value in computed tomography (CT), and histo-pathological results." | 8.31 | Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology. ( Elgörmüş, ÇS; Erbaş, O; Gür, SG; Özkul, B; Sever, İH; Yiğittürk, G, 2023) |
| "In order to investigate the expression levels of procalcitonin (PCT), B-type brain natriuretic peptide (BNP), and lactic acid (Lac) in serum of patients with sepsis, a retrospective analysis is conducted." | 8.12 | Early Diagnosis and Prediction of Death Risk in Patients with Sepsis by Combined Detection of Serum PCT, BNP, Lactic Acid, and Apache II Score. ( Chen, X; Huang, H; Liu, C; Luo, L; Song, Y; Suo, S, 2022) |
| "This study investigated the prognostic value of the albumin-to-fibrinogen ratio (AFR) in patients with sepsis as a consequence of infection at various sites." | 8.12 | Prognostic Value of Albumin-to-Fibrinogen Ratio for 28-Day Mortality among Patients with Sepsis from Various Infection Sites. ( Chang, B; Li, S; Shen, Y; Wang, N, 2022) |
| "In order to explore the effective markers of presepsis in the prediction of clinical disease and disease severity, the predictive effect of lactic acid (Lac) combined with cardiac troponin T (cTnT) and 5-hydroxytryptophan (5-HT) on the severity of sepsis in intensive care unit (ICU) patients and its correlation with prognosis is investigated." | 8.12 | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis. ( Jiang, M; Wang, X; Wu, W; Zhao, C, 2022) |
| "To investigate the association of inhaled albuterol with lactate clearance in patients with sepsis." | 8.02 | Inhaled Albuterol Use and Impaired Lactate Clearance in Patients With Sepsis: A Retrospective Cohort Study. ( Kuno, T; Maeda, T; Paralkar, J; Patrawalla, P, 2021) |
| "To investigate the assessment values of procalcitonin (PCT), lactic acid (LAC), sequential organ failure assessment (SOFA) score and acute physiology and chronic health evaluation II (APACHE II) score in patients with sepsis." | 7.91 | [Assessment values of procalcitonin, lactic acid, and disease severity scores in patients with sepsis]. ( Guo, S; Liu, W; Wang, H; Wang, J; Zhang, D, 2019) |
| "To investigate the changes and clinical significances of intestinal fatty acid binding protein (I-FABP) and D-lactic acid levels in early intestinal injury of patients with sepsis and septic shock." | 7.91 | [Clinical significance on serum intestinal fatty acid binding protein and D-lactic acid levels in early intestinal injury of patients with sepsis]. ( Liu, D; Wang, Y; Yan, J; Yang, X; Zhang, X, 2019) |
| "Lactic acidosis in the emergency department and other hospital settings is typically due to tissue hypoxia with sepsis being the most common cause." | 7.88 | Lactic Acidosis in a Critically Ill Patient: Not Always Sepsis. ( Leger, KJ; Schuh, AM; Summers, C; Uspal, NG, 2018) |
| "We aimed to evaluate the impact of metformin use on lactate kinetics in patients with severe sepsis and septic shock." | 7.85 | Impact of Metformin Use on Lactate Kinetics in Patients with Severe Sepsis and Septic Shock. ( Carriere, KC; Cha, WC; Hwang, SY; Jeon, K; Jo, IJ; Lee, TR; Park, J; Shin, TG; Sim, MS; Suh, GY; Yeon, S; Yoon, H, 2017) |
| "To investigate the value of blood lactic acid (BLA) in evaluating disease severity and prognosis in children with sepsis." | 7.83 | [Value of blood lactic acid in evaluating disease severity and prognosis in children with sepsis]. ( Liu, PP; Lu, XL; Qiu, J; Yan, HP; Zhu, YM; Zuo, C, 2016) |
| "Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered." | 7.83 | Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study. ( Chan, KS; Tseng, KL; Weng, SF; Yang, CC, 2016) |
| "This study aims to assess the risk of morbidity associated with maternal lactic acid concentration in women with possible sepsis in pregnancy." | 7.81 | Lactic acid measurement to identify risk of morbidity from sepsis in pregnancy. ( Albright, CM; Ali, TN; Anderson, BL; Lopes, V; Rouse, DJ, 2015) |
| "005) after controlling for serum lactic acid levels and Sepsis-related Organ Failure Assessment score." | 7.81 | Association between serum substance P levels and mortality in patients with severe sepsis. ( Almeida, T; Díaz, C; Ferreres, J; Hernández, M; Jiménez, A; Labarta, L; Lorente, L; Martín, MM; Solé-Violán, J, 2015) |
| " Here we investigate whether exogenous carbon monoxide can protect cardiac function and improve survival against sepsis by interfering with mitochondrial energetic metabolism." | 7.80 | A novel role of exogenous carbon monoxide on protecting cardiac function and improving survival against sepsis via mitochondrial energetic metabolism pathway. ( Cao, J; Liu, D; Qin, W; Qiu, X; Sun, B; Wang, X, 2014) |
| "To explore the effect of ethyl pyruvate (EP) and alkaline phosphatase (ALP) on injuries of sepsis and the mechanism involved." | 7.75 | [Effects of ethyl pyruvate on injuries of sepsis in mice]. ( Deng, ZH; Lin, J; Ti, DD; Wang, LH; Xue, H; Yan, GT, 2009) |
| "To compare the prognostic abilities of lactic acidosis and hyperlactatemia and determine the influence of metabolic acidosis when attempting to predict the outcome of septic patients using serum lactate levels." | 7.74 | Lactic acidosis not hyperlactatemia as a predictor of in hospital mortality in septic emergency patients. ( Baek, KJ; Choi, SH; Hong, YS; Kim, JY; Lee, SW; Moon, SW; Park, DW; Park, JS, 2008) |
| "To determine whether the combined administration of adrenomedullin and adrenomedullin binding protein-1 (AM/AMBP-1) has any modulatory effects on the cardiovascular response during the progression of sepsis." | 7.71 | Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1. ( Chaudry, IH; Wang, P; Yang, S; Zhou, M, 2002) |
| "Our recent study indicates that administration of adrenomedullin (AM) in combination with AM-binding protein-1 (AMBP-1) before sepsis (i." | 7.71 | Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin-binding protein-1 in sepsis: down-regulation of proinflammatory cytokines. ( Fowler, DE; Wang, P; Yang, S; Zhou, M, 2002) |
| "This study has been performed to characterize the relationship between changes in plasma taurine (TAU) and hemodynamic patterns in sepsis." | 7.70 | Taurine and pulmonary hemodynamics in sepsis. ( Boldrini, G; Castagneto, M; Chiarla, C; Giovannini, I; Siegel, JH, 2000) |
| "The influence of pentoxifylline (PTX) on mortality and some important mediators was studied in a model of cecal perforation with fulminant intra-abdominal sepsis in rats." | 7.69 | Pentoxifylline improves survival and reduces tumor necrosis factor, interleukin-6, and endothelin-1 in fulminant intra-abdominal sepsis in rats. ( Ekstrøm, P; Giercksky, KE; Lundblad, R, 1995) |
| "Sepsis is a common complication of severe pediatric pneumonia, characterized by difficulty in treatment, a high treatment cost, high morbidity and mortality, and poor prognosis." | 5.91 | Clinical Significance of Procalcitonin, Lactic Acid, and Endotoxin Testing for Children With Severe Pneumonia and Sepsis. ( Lu, Y; Song, L, 2023) |
| "Treatment with remifentanil reduced the expression of lactic acid, pyruvate, and epinephrine in the heart and kidney tissues and attenuated the expression of PDK4 messenger RNA and PDK4 protein in the myocardial tissue." | 5.72 | Remifentanil reduces multiple organ and energy metabolism disturbances in a rat sepsis model. ( Chen, X; Liao, XY; Lin, JD; Wu, Y; Wu, ZZ; Yang, MX; Zhang, BL, 2022) |
| "Sepsis was induced by cecal ligation and puncture and gluconeogenesis was assessed in liver perfusion." | 5.62 | Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis. ( Bertolini, GL; Biazi, GR; de Souza Galia, WB; de Souza, HM; Frasson-Uemura, IG; Miksza, DR; Zaia, CTBV; Zaia, DAM, 2021) |
| "Thiamine is an essential co-factor for aerobic metabolism." | 5.56 | Thiamine status and lactate concentration in sepsis: A prospective observational study. ( Annane, D; Bounab, R; Chevret, S; Heming, N; Meng, P; Salah, A; Sivanandamoorthy, S, 2020) |
| "Sepsis is a complex disorder with very high morbidity and mortality; it can occur when an immune disorder triggers an invasion of pathogens in the host." | 5.56 | Inflammation-targeting polymeric nanoparticles deliver sparfloxacin and tacrolimus for combating acute lung sepsis. ( Ding, Y; Fan, B; Mao, Z; Wang, W; Wang, Y; Wu, J; Yang, Y, 2020) |
| "In cases of Polytrauma induced sepsis or septic shock, the level started to increase within first 72 hours after traumatic injury, pick concentration was achieved within first 25 days high from the beginning and dynamically increases within first 25 days, the tendency of gradual decrease was seen after 30 days." | 5.48 | THE ROLE OF PROCALCITONIN AND BLOOD LACTIC ACID VALUES IN PROGNOSIS OF SEPSIS AND SEPTIC SHOCK IN POLYTRAUMA PATIENTS. ( Kanashvili, B; Ratiani, L; Saganelidze, K, 2018) |
| "Sepsis is a serious complication for patients with obstructive jaundice." | 5.36 | Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats. ( Wang, P; Wu, R; Yang, J; Zhou, M, 2010) |
| "This study assessed the ability of mid-regional proadrenomedullin (MR-proADM) in comparison to conventional biomarkers (procalcitonin (PCT), lactate, C-reactive protein) and clinical scores to identify disease severity in patients with sepsis." | 5.27 | The use of mid-regional proadrenomedullin to identify disease severity and treatment response to sepsis - a secondary analysis of a large randomised controlled trial. ( Bloos, F; Briegel, J; Brunkhorst, FM; Elke, G; Jaschinski, U; Kluge, S; Loeffler, M; Meybohm, P; Moerer, O; Nierhaus, A; Reinhart, K; Weyland, A; Wilson, DC, 2018) |
| "Sepsis was induced in chronically catheterized conscious rats by multiple injections of live Escherichia coli via a subcutaneous catheter." | 5.27 | Inhibition of eicosanoid production by BW755C does not attenuate sepsis-induced alterations in glucose kinetics. ( Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ, 1987) |
| " However, no study has yet discovered which factor is most important for mortality in severe sepsis patients with lactic acidosis." | 5.20 | Lactate Clearance and Vasopressor Seem to Be Predictors for Mortality in Severe Sepsis Patients with Lactic Acidosis Supplementing Sodium Bicarbonate: A Retrospective Analysis. ( An, WS; Jeong, HJ; Kim, EB; Kim, SE; Lee, SM; Son, YK, 2015) |
| "The use of heparin at the earlier period of sepsis can inhibit the lowering of PLT and increase of D-dimer and lactic acid significantly, prevent microvascular thrombosis, improve the tissue perfusion, and decrease active bleeding." | 5.13 | [The study of the mechanism of the effect of heparin on tissue perfusion of sepsis patients]. ( Chen, J; Chen, MY; Guan, XD; Huang, SW; Kou, QY; Li, LF; Liu, ZM; Ouyang, B; Wu, JF; Yang, CH, 2008) |
| "Levosimendan and dobutamine are extensively used to treat sepsis-associated cardiovascular failure in ICU." | 5.12 | Levosimendan versus dobutamine for sepsis-induced cardiac dysfunction: a systematic review and meta-analysis. ( Chen, J; Chen, WT; Lei, YY; Lin, XF; Liu, DH; Liu, YY; Ning, YL; Xian, SX; Yang, ZQ, 2021) |
| " With serum lactate values > 10 mmol/l 80 % of the patients die in intensive care, and if the severe lactic acidosis persists for 48 hours, all patients die." | 4.98 | [Lactic acidosis - update 2018]. ( de Heer, G; Fuhrmann, V; Jarczak, D; Kluge, S; Nierhaus, A, 2018) |
| " Sustained lactic acidosis, or changes in lactate in response to inotropic support, are useful predictors of mortality in severe sepsis and trauma, and superior to hemodynamic markers such as DO2 and VO2." | 4.80 | Lactate in sepsis and trauma--hindrance or help? ( Sladen, RN, 1999) |
| "In our data, preadmission metformin use is associated with a significantly larger decrease in lactate after admission with sepsis or septic shock and with reduced mortality in septic shock." | 4.31 | New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study. ( De Decker, K; De Neve, N; Tackaert, T; Van Moorter, N; Van Vlem, B, 2023) |
| "To explore the predictive value of serum sodium variability within 72 hours, lactic acid (Lac), sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation II (APACHE II) in predicting the 28-day prognosis of sepsis patients." | 4.31 | [Prognostic value of serum sodium variability within 72 hours and lactic acid combined with severity score in patients with sepsis]. ( Chi, H; Hu, D; Li, Q; Lian, Z; Wang, H; Zhang, C; Zhang, S, 2023) |
| "Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate the effect of papaverine on RAGE associated NF-κB pathway by determining the level of soluble RAGE (sRAGE) and HMGB1, and to support this hypothesis by evaluating inflammatory biochemical, oxidative stress markers, Hounsfield unit (HU) value in computed tomography (CT), and histo-pathological results." | 4.31 | Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology. ( Elgörmüş, ÇS; Erbaş, O; Gür, SG; Özkul, B; Sever, İH; Yiğittürk, G, 2023) |
| "05) between two groups, which included birth weight (BW), weight on admission, gestational age, age on admission, mode of delivery, septic shock, heart failure, respiratory failure, pulmonary hypertension, hypothermia, serum lactic acid, and aspartate aminotransferase (AST)." | 4.31 | Risk factors for death caused by early onset sepsis in neonates: a retrospective cohort study. ( Chen, F; Chen, X; He, H; Hu, Y; Wei, H, 2023) |
| "In order to investigate the expression levels of procalcitonin (PCT), B-type brain natriuretic peptide (BNP), and lactic acid (Lac) in serum of patients with sepsis, a retrospective analysis is conducted." | 4.12 | Early Diagnosis and Prediction of Death Risk in Patients with Sepsis by Combined Detection of Serum PCT, BNP, Lactic Acid, and Apache II Score. ( Chen, X; Huang, H; Liu, C; Luo, L; Song, Y; Suo, S, 2022) |
| "This study investigated the prognostic value of the albumin-to-fibrinogen ratio (AFR) in patients with sepsis as a consequence of infection at various sites." | 4.12 | Prognostic Value of Albumin-to-Fibrinogen Ratio for 28-Day Mortality among Patients with Sepsis from Various Infection Sites. ( Chang, B; Li, S; Shen, Y; Wang, N, 2022) |
| "In order to explore the effective markers of presepsis in the prediction of clinical disease and disease severity, the predictive effect of lactic acid (Lac) combined with cardiac troponin T (cTnT) and 5-hydroxytryptophan (5-HT) on the severity of sepsis in intensive care unit (ICU) patients and its correlation with prognosis is investigated." | 4.12 | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis. ( Jiang, M; Wang, X; Wu, W; Zhao, C, 2022) |
| "The authors design an animal model of neonatal sepsis to analyze the treatment of neonatal septic shock with Methylene Blue (MB) in a swine model." | 4.12 | Methylene Blue to Neonatal Septic Shock treatment in neonate pigs ( Albuquerque, AAS; de Castro, RSAP; Evora, PRB; Ferreira, CHF; Gonçalves-Ferri, WA; Oharomari, LK; Silva Lessa, DF, 2022) |
| "Our data indicate that CRP, ESR, lactic acid, and procalcitonin elevations were all specific, but not sensitive, in identifying children in the ED with SIRS who go on to develop severe sepsis." | 4.02 | Utility of specific laboratory biomarkers to predict severe sepsis in pediatric patients with SIRS. ( Baker, A; Byler, S; Eisenberg, MA; Freiman, E; Herigon, JC, 2021) |
| "To investigate the association of inhaled albuterol with lactate clearance in patients with sepsis." | 4.02 | Inhaled Albuterol Use and Impaired Lactate Clearance in Patients With Sepsis: A Retrospective Cohort Study. ( Kuno, T; Maeda, T; Paralkar, J; Patrawalla, P, 2021) |
| "We evaluated the ability of four biomarkers (C-Reactive protein (CRP), lactate, mid-regional proadrenomedullin (MR-proADM) and procalcitonin (PCT)) to detect each kind of organ failure considered in the SOFA in 213 patients with infection, sepsis or septic shock, by using multivariate regression analysis and calculation of the area under the receiver operating curve (AUROC)." | 3.96 | MR- proADM to detect specific types of organ failure in infection. ( Aldecoa, C; Almansa, R; Andaluz-Ojeda, D; Andrés, C; Bermejo-Martin, JF; Calvo, D; Cicuendez, R; Esteban-Velasco, MC; Martín, S; Martin-Fernandez, M; Muñoz-Bellvís, L; Nogales, L; Ríos-Llorente, A; Sanchez-Barrado, E; Vaquero-Roncero, LM, 2020) |
| "To investigate the assessment values of procalcitonin (PCT), lactic acid (LAC), sequential organ failure assessment (SOFA) score and acute physiology and chronic health evaluation II (APACHE II) score in patients with sepsis." | 3.91 | [Assessment values of procalcitonin, lactic acid, and disease severity scores in patients with sepsis]. ( Guo, S; Liu, W; Wang, H; Wang, J; Zhang, D, 2019) |
| "Amino acid derangements are common in severe falciparum malaria and have been associated with endothelial dysfunction (L-arginine), metabolic acidosis (alanine and lactate), and disease severity (phenylalanine and tryptophan metabolites)." | 3.91 | Amino acid derangements in adults with severe falciparum malaria. ( Apinan, S; Barua, A; Day, NPJ; Dondorp, AM; Dutta, AK; Ghose, A; Hossain, A; Kingston, HW; Leopold, SJ; Paul, S; Plewes, KA; Sattar, A; Tarning, J; White, NJ; Winterberg, M, 2019) |
| "To investigate the changes and clinical significances of intestinal fatty acid binding protein (I-FABP) and D-lactic acid levels in early intestinal injury of patients with sepsis and septic shock." | 3.91 | [Clinical significance on serum intestinal fatty acid binding protein and D-lactic acid levels in early intestinal injury of patients with sepsis]. ( Liu, D; Wang, Y; Yan, J; Yang, X; Zhang, X, 2019) |
| " The aim of this study was to investigate the prediction efficiency of lymphopenia and other clinical markers, such as white blood cell (WBC), neutrophil count (N#), procalcitonin (PCT), and arterial lactic acid (Lac) in the diagnosis and prognosis assessment for adult patients with nonviral infection-related sepsis." | 3.91 | Nonviral infection-related lymphocytopenia for the prediction of adult sepsis and its persistence indicates a higher mortality. ( Chen, M; Du, H; He, F; Jiang, J; Li, X; Niu, B; Ren, G; Su, Y; Zhang, J, 2019) |
| "Lactic acidosis in the emergency department and other hospital settings is typically due to tissue hypoxia with sepsis being the most common cause." | 3.88 | Lactic Acidosis in a Critically Ill Patient: Not Always Sepsis. ( Leger, KJ; Schuh, AM; Summers, C; Uspal, NG, 2018) |
| "We aimed to evaluate the impact of metformin use on lactate kinetics in patients with severe sepsis and septic shock." | 3.85 | Impact of Metformin Use on Lactate Kinetics in Patients with Severe Sepsis and Septic Shock. ( Carriere, KC; Cha, WC; Hwang, SY; Jeon, K; Jo, IJ; Lee, TR; Park, J; Shin, TG; Sim, MS; Suh, GY; Yeon, S; Yoon, H, 2017) |
| "To investigate the value of blood lactic acid (BLA) in evaluating disease severity and prognosis in children with sepsis." | 3.83 | [Value of blood lactic acid in evaluating disease severity and prognosis in children with sepsis]. ( Liu, PP; Lu, XL; Qiu, J; Yan, HP; Zhu, YM; Zuo, C, 2016) |
| "Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered." | 3.83 | Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study. ( Chan, KS; Tseng, KL; Weng, SF; Yang, CC, 2016) |
| "This study aims to assess the risk of morbidity associated with maternal lactic acid concentration in women with possible sepsis in pregnancy." | 3.81 | Lactic acid measurement to identify risk of morbidity from sepsis in pregnancy. ( Albright, CM; Ali, TN; Anderson, BL; Lopes, V; Rouse, DJ, 2015) |
| " Serum levels of melatonin were measured at moment of severe sepsis diagnosis." | 3.81 | Serum melatonin levels are associated with mortality in severe septic patients. ( Abreu-González, P; Borreguero-León, JM; de la Cruz, T; Díaz, C; Ferreres, J; Jiménez, A; Labarta, L; Lorente, L; Martín, MM; Solé-Violán, J, 2015) |
| "005) after controlling for serum lactic acid levels and Sepsis-related Organ Failure Assessment score." | 3.81 | Association between serum substance P levels and mortality in patients with severe sepsis. ( Almeida, T; Díaz, C; Ferreres, J; Hernández, M; Jiménez, A; Labarta, L; Lorente, L; Martín, MM; Solé-Violán, J, 2015) |
| " Here we investigate whether exogenous carbon monoxide can protect cardiac function and improve survival against sepsis by interfering with mitochondrial energetic metabolism." | 3.80 | A novel role of exogenous carbon monoxide on protecting cardiac function and improving survival against sepsis via mitochondrial energetic metabolism pathway. ( Cao, J; Liu, D; Qin, W; Qiu, X; Sun, B; Wang, X, 2014) |
| " DIC patients showed higher Sequential Organ Failure Assessment (SOFA) scores, the prevalence of multiple organ dysfunction syndrome (MODS) and more increased soluble fibrin and lactate levels." | 3.79 | The dynamics of angiogenic factors and their soluble receptors in relation to organ dysfunction in disseminated intravascular coagulation associated with sepsis. ( Gando, S; Jesmin, S; Sultana, SS; Wada, T; Zaedi, S, 2013) |
| " As melatonin is an antioxidant with the potential to scavenge radicals in mitochondria, we therefore employed a sepsis model, that is, cecal ligation and double puncture (CLP) in rats, to study the melatonin effects on: (i), myocardial mitochondrial function; (ii), heart systolic function; and (iii), prognosis of septic rats." | 3.79 | Melatonin improved rat cardiac mitochondria and survival rate in septic heart injury. ( Chai, W; Chen, X; Liu, D; Long, Y; Rui, X; Wang, H; Wang, X; Yang, Q; Zhang, H; Zhang, Q; Zhou, X, 2013) |
| "To evaluate the effect of early application of high-volume hemofiltration treatment (HVHF) on the levels of lactic acid, pro-inflammatory cytokines and C-reactive protein (CRP) in plasma, as well as APACHE II score in patients suffering from severe sepsis." | 3.76 | [Early high-volume hemofiltration treatment in severe sepsis]. ( Cheng, BL; Jin, Y; Lou, TZ; Qiu, ZL; Xu, JL; Zhang, N, 2010) |
| "To explore the effect of ethyl pyruvate (EP) and alkaline phosphatase (ALP) on injuries of sepsis and the mechanism involved." | 3.75 | [Effects of ethyl pyruvate on injuries of sepsis in mice]. ( Deng, ZH; Lin, J; Ti, DD; Wang, LH; Xue, H; Yan, GT, 2009) |
| "To compare the prognostic abilities of lactic acidosis and hyperlactatemia and determine the influence of metabolic acidosis when attempting to predict the outcome of septic patients using serum lactate levels." | 3.74 | Lactic acidosis not hyperlactatemia as a predictor of in hospital mortality in septic emergency patients. ( Baek, KJ; Choi, SH; Hong, YS; Kim, JY; Lee, SW; Moon, SW; Park, DW; Park, JS, 2008) |
| "Lactic acidosis and increased production of CO(2) are common in septic shock." | 3.72 | Increased tissue oxygen extraction and acidosis with progressive severity of sepsis. ( Chinkes, DL; Gore, DC; Hart, DW, 2003) |
| " aeruginosa, hepatic oxygen delivery and consumption increased with early sepsis whereas there were no alterations in the concentrations of adenine nucleotides or NAD(+)/NADH within liver." | 3.72 | Sepsis-induced failure of hepatic energy metabolism. ( Asimakis, GK; Chinkes, DL; Gore, DC; Hart, DW; Rinehart, AJ, 2003) |
| "Our data demonstrated that measures adopted in the second period for patients with delayed fluid resuscitation, including early excision, early rapid adequate resuscitation, early enteral feeding, increased immunity function, early applying antibactials, xenotransfusion of ultraviolet-irradiated blood, application of recombinant human-growth factor (rh-GH), epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), are beneficial to the prevention and treatment of sepsis in severely burned patients with delayed fluid resuscitation." | 3.72 | [An early comprehensive prevention and treatment of sepsis in severely burned patients with delayed fluid resuscitation]. ( Liu, M; Liu, SK; Wu, ZH; Xia, ZF; Zhan, XH, 2004) |
| "To determine whether the combined administration of adrenomedullin and adrenomedullin binding protein-1 (AM/AMBP-1) has any modulatory effects on the cardiovascular response during the progression of sepsis." | 3.71 | Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1. ( Chaudry, IH; Wang, P; Yang, S; Zhou, M, 2002) |
| "Our recent study indicates that administration of adrenomedullin (AM) in combination with AM-binding protein-1 (AMBP-1) before sepsis (i." | 3.71 | Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin-binding protein-1 in sepsis: down-regulation of proinflammatory cytokines. ( Fowler, DE; Wang, P; Yang, S; Zhou, M, 2002) |
| "Bacterial sepsis is frequently accompanied by increased blood concentration of lactic acid, which traditionally is attributed to poor tissue perfusion, hypoxia and anaerobic glycolysis." | 3.71 | Role of skeletal muscle Na+-K+ ATPase activity in increased lactate production in sub-acute sepsis. ( Fischer, JE; Friend, LA; James, JH; King, JK; McCarter, FD; Nierman, SR; Wang, L, 2002) |
| "This study has been performed to characterize the relationship between changes in plasma taurine (TAU) and hemodynamic patterns in sepsis." | 3.70 | Taurine and pulmonary hemodynamics in sepsis. ( Boldrini, G; Castagneto, M; Chiarla, C; Giovannini, I; Siegel, JH, 2000) |
| "The influence of pentoxifylline (PTX) on mortality and some important mediators was studied in a model of cecal perforation with fulminant intra-abdominal sepsis in rats." | 3.69 | Pentoxifylline improves survival and reduces tumor necrosis factor, interleukin-6, and endothelin-1 in fulminant intra-abdominal sepsis in rats. ( Ekstrøm, P; Giercksky, KE; Lundblad, R, 1995) |
| "Sepsis was induced by fecal peritonitis." | 3.30 | Neutralization of extracellular histones by sodium-Β-O-methyl cellobioside sulfate in septic shock. ( Annoni, F; Creteur, J; Dewachter, L; Eycken, MV; Favory, R; Garcia, B; Herpain, A; Khaldi, A; Li, N; Manicone, F; Moiroux-Sahraoui, A; Moreau, A; Remmelink, M; Shi, L; Su, F; Taccone, FS; Vincent, JL; Wang, Y, 2023) |
| "Eligible septic shock patients who consented to participation in the study were randomly assigned to receive early lactate-guided treatment or regular treatment as controls." | 3.11 | Early Lactate-Guided Resuscitation of Elderly Septic Patients. ( Chen, H; Tong, F; Wang, X; Wang, Y; Xu, J, 2022) |
| "Fifty-eight patients with severe sepsis were randomly assigned to receive either magnesium (n = 30) or placebo (n = 28)." | 2.94 | Effect of magnesium supplementation on lactate clearance in critically ill patients with severe sepsis: a randomized clinical trial. ( Abdollahi, A; Khalili, H; Mohammadi, M; Noormandi, A, 2020) |
| "Early detection of sepsis is challenging to achieve with current diagnostic methods, leading to expenditures of $27 billion annually in the United States with significant associated mortality." | 2.82 | Recent Advances in Bedside Device-Based Early Detection of Sepsis. ( C Sheridan, D; D Somogyi, R, 2022) |
| "Septic shock is characterized by hypotension requiring vasopressors after adequate fluid resuscitation with elevated lactate." | 2.82 | Sepsis Management for the Nephrologist. ( Dellinger, RP; Patel, S; Puri, N, 2022) |
| "Adult patients with severe sepsis and systolic blood pressure less than 90 mm Hg despite intravascular volume expansion and/or serum lactate greater than or equal to 4." | 2.79 | Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis*. ( Anderson, K; Chansky, ME; Dellinger, RP; Dezfulian, C; Durflinger, P; Glaspey, LJ; Hollenberg, SM; Parrillo, JE; Roberts, BW; Trzeciak, S, 2014) |
| "Goal-directed resuscitation for severe sepsis and septic shock has been reported to reduce mortality when applied in the emergency department." | 2.75 | Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. ( Arnold, RC; Claremont, HA; Jones, AE; Kline, JA; Shapiro, NI; Trzeciak, S, 2010) |
| " A volume therapy with exclusively crystalloids or colloids with the chosen colloid hyperoncotic, hyperchloremic HES solution (10% hydroxyethyl starch: 10% Hemohes) or the crystalloid solution with high lactate content (Sterofundin) is neither acceptable nor practicable, even if only due to exceeding the maximum dosage as recommended by the manufacturer." | 2.73 | [The design of the VISEP trial. Critical appraisal]. ( Boldt, J; Engelmann, L; Mertzlufft, F; Sirtl, C; Stuttmann, R; Zander, R, 2007) |
| "Sepsis is a common disease process encountered by physicians." | 2.72 | Macrocirculatory and Microcirculatory Endpoints in Sepsis Resuscitation. ( Gray, S; Hendin, A; Hickey, M; Mok, G; Reardon, P; Yadav, K, 2021) |
| "In patients with severe sepsis or septic shock, 250 ml HS transiently (<120 min) increases CI and PCWP and induces an increase in sodium and chloride concentrations." | 2.71 | [Short term effects of hypertonic saline during severe sepsis and septic shock]. ( de La Coussaye, JE; Eledjam, JJ; Jaber, S; Lefrant, JY; Louart, G; Mahamat, A; Muller, L; Ripart, J, 2004) |
| "A convenience cohort of patients with severe sepsis or septic shock." | 2.71 | Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. ( Jacobsen, G; Knoblich, BP; Muzzin, A; Nguyen, HB; Ressler, JA; Rivers, EP; Tomlanovich, MC, 2004) |
| "Sepsis was identified as Gram-positive in 49 patients, Gram-negative in 40, mixed in 37, and unknown in 26." | 2.69 | Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis. ( Bakker, J; Curtis, L; Spapen, H; Vincent, JL; Webster, NR, 2000) |
| "Sepsis is the most common critical illness in the clinic, with a high incidence and mortality." | 2.61 | Qinwen Baidu decoction for sepsis: A protocol for a systematic review and meta-analysis. ( Cai, H; Cao, Q; Chen, D; Huang, H; Huang, Y; Li, S; Peng, X; Wang, P; Zhong, J, 2019) |
| "Sepsis is characterised by organ dysfunction resulting from infection, with no reliable single objective test and current diagnosis based on clinical features and results of investigations." | 2.58 | Review article: Sepsis in the emergency department - Part 2: Investigations and monitoring. ( Bellomo, R; de Groot, B; Finfer, S; Fraser, JF; Iredell, J; Keijzers, G; Macdonald, SP; Shetty, A; Tang, B; Thompson, K; Williams, JM, 2018) |
| "The new definitions of sepsis and septic shock reflect the inadequate sensitivity, specify, and lack of prognostication of systemic inflammatory response syndrome criteria." | 2.55 | Sepsis and Septic Shock Strategies. ( Armstrong, BA; Betzold, RD; May, AK, 2017) |
| "Accordingly, sepsis is now defined as a life-threatening organ dysfunction due to a falsely regulated response of the body to an infection." | 2.55 | [Updated definition of sepsis : Implications for diagnostics and therapy principles]. ( Schlegel, N, 2017) |
| "Sepsis is newly defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection." | 2.53 | Sepsis: Updated definitions and optimized management. ( Panknin, HT; Schröder, S; Trautmann, M, 2016) |
| "The current practice in treatment of severe sepsis and septic shock is to ensure adequate oxygenation and perfusion in patients, along with prompt administration of antibiotics, within 6 hours from diagnosis, which is considered the "golden hour" for the patients." | 2.53 | The role of central venous oxygen saturation, blood lactate, and central venous-to-arterial carbon dioxide partial pressure difference as a goal and prognosis of sepsis treatment. ( Chattipakorn, N; Chentanakij, B; Sruamsiri, K; Wittayachamnankul, B, 2016) |
| "When sepsis is accompanied by conditions in which systemic oxygen delivery does not meet tissue oxygen demands, tissue hypoperfusion begins." | 2.52 | Oxygen extraction and perfusion markers in severe sepsis and septic shock: diagnostic, therapeutic and outcome implications. ( Disselkamp, M; Gill, J; Jaehne, AK; Rivers, EP; Yataco, AC, 2015) |
| "Sepsis is a global health problem." | 2.49 | [Initial resuscitation bundle and monitoring tissue perfusion in severe sepsis]. ( Hernández P, G; Romero P, C, 2013) |
| "MEDS' prognostic accuracy in severe sepsis is inferior to undifferentiated systemic inflammatory response syndrome (SIRS) patients." | 2.45 | Risk stratification of the potentially septic patient in the emergency department: the Mortality in the Emergency Department Sepsis (MEDS) score. ( Carpenter, CR; Keim, SM; Nguyen, HB; Upadhye, S, 2009) |
| "Sepsis affects the cardiovascular system through multiple mechanisms, and often these derangements result in tissue hypoperfusion." | 2.45 | Sepsis-induced tissue hypoperfusion. ( Jones, AE; Puskarich, MA, 2009) |
| "Patients with sepsis-induced multiple organ failure often experience muscle fatigue in both locomotive and respiratory muscles." | 2.44 | Mitochondrial function in sepsis: respiratory versus leg muscle. ( Fredriksson, K; Rooyackers, O, 2007) |
| "Sepsis and multiple organ failure are characterized by an excessive release of inflammatory mediators and a marked stimulation of stress hormones." | 2.44 | Substrate utilization in sepsis and multiple organ failure. ( Chioléro, R; Tappy, L, 2007) |
| "The recognition of severe sepsis should be accompanied without delay by very well defined therapeutic measures." | 2.43 | The role of bundles in sepsis care. ( Hurtado, FJ; Nin, N, 2006) |
| "A common feature of acute liver failure and sepsis is a hypermetabolic state with enhanced glycolysis and production of lactate and pyruvate." | 2.42 | Splanchnic metabolism in acute liver failure and sepsis. ( Clemmesen, O; Larsen, FS; Ott, P, 2004) |
| "This is also true for patients in septic shock after plasma volume expansion." | 2.39 | [Is infection and septic shock caused by a global oxygen deficiency? An overview in 2 parts. 1: Infection and correlation between DO2 and VO2]. ( Ensinger, H; Georgieff, M, 1996) |
| "Sepsis is frequently characterized by a number of metabolic abnormalities: increased plasma lactate concentration, metabolic acidosis, increased glycolysis, and an abnormal "delivery-dependent" oxygen consumption." | 2.38 | Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis. ( Hotchkiss, RS; Karl, IE, 1992) |
| "Its presence in patients with adult respiratory distress syndrome and/or sepsis has been associated with particularly high mortality rates that may be the result of tissue hypoxia that causes multiple organ failure." | 2.38 | Experimental models of pathologic oxygen supply dependency. ( Cain, SM; Curtis, SE, 1991) |
| "Patients with sepsis or septic shock according to Sepsis-3 Consensus criteria." | 1.91 | Association between septic patient mortality and blood survivin concentrations. ( Ferrer-Moure, C; González-Rivero, AF; Jiménez, A; Lorente, L; Martín, MM; Ortiz-López, R; Pérez-Cejas, A, 2023) |
| "Sepsis is a global medical issue owing to its unacceptably high mortality rate." | 1.91 | 28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study. ( Chen, H; Chen, W; Chen, Y; Xie, Y; Zhuang, D; Zou, S, 2023) |
| "Patients with severe sepsis had significantly elevated levels of HBP compared with sepsis (median 170." | 1.91 | Heparin-binding protein as a biomarker of severe sepsis in the pediatric intensive care unit: A multicenter, prospective study. ( Chen, D; Dai, S; Gao, F; Gao, L; Huang, C; Lin, J; Liu, J; Liu, P; Long, G; Lou, J; Ma, L; Mo, L; Qu, W; Shang, S; Wong, C; Wu, H; Xu, J; Yan, G; Zhou, Z; Zou, Y, 2023) |
| "Sepsis is a critical illness often encountered in the intensive care unit." | 1.91 | Baseline red blood cell distribution width and perforin, dynamic levels of interleukin 6 and lactate are predictors of mortality in patients with sepsis. ( Li, X; Sun, Y; Wang, M; Xue, L; Yan, W; Yin, Z; Zhou, Q, 2023) |
| "Acute respiratory failure is a type of sepsis complicated by severe organ failure." | 1.91 | Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study. ( He, Q; Luo, M, 2023) |
| "Sepsis is a dreaded complication in patients with postcardiotomy cardiogenic shock, especially ECMO-associated sepsis." | 1.91 | ( Abdullatif, MT; Aboughanima, MA; Albabtain, MA; AlBarak, MM; Arafat, AA; Azar, B; Belghith, M; Elshoura, YA; Gross, I; Hashavya, S; Ohana Sarna Cahan, L; Osman, AA; Reif, S; Tantway, TM, 2023) |
| "Sepsis is a potentially life-threatening systemic dysregulatory response to infection, and septic shock occurs when sepsis leads to systemic vasodilation and subsequent tissue hypoperfusion." | 1.91 | How Would You Resuscitate This Patient With Septic Shock? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center. ( Bell, TD; Berg, K; Kanjee, Z; Reynolds, EE, 2023) |
| "Sepsis is a common complication of severe pediatric pneumonia, characterized by difficulty in treatment, a high treatment cost, high morbidity and mortality, and poor prognosis." | 1.91 | Clinical Significance of Procalcitonin, Lactic Acid, and Endotoxin Testing for Children With Severe Pneumonia and Sepsis. ( Lu, Y; Song, L, 2023) |
| "In 2015, the Severe Sepsis and Early Septic Shock Management Bundle (SEP-1) tied hospital reimbursement to performance on a series of time sensitive indicators, including ordering blood cultures on patients with severe sepsis or septic shock." | 1.91 | Overcultured? Blood cultures on discharged ED patients were ordered more frequently after the SEP-1 bundle initiation. ( Lamonge, R; Rech, MA; Semenchuck, N; Sterk, E; Wassermann, T, 2023) |
| "The incidence of acute respiratory distress syndrome (ARDS), cTn I and brain natriuretic peptic in the improved group were significantly lower than those in the control group." | 1.91 | Practice and effect evaluation of early restrictive fluid resuscitation strategy in the nursing care of patients with sepsis in the emergency department: a retrospective cohort study. ( Dai, X; Hu, X; Wang, P; Zhang, J, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection." | 1.91 | Mean Serum Lactate Levels in Patients with Sepsis Presenting to the Department of Emergency Medicine of a Tertiary Care Center: A Descriptive Cross-sectional Study. ( Adhikari, N; Chapagain, N; Ghimire, U; Pandey, S; Pradhan, B; Pradhan, S, 2023) |
| "The general condition of patients with malignancy who have referred to the emergency department should be evaluated and it should be shown that they are not in any oncological emergency." | 1.91 | Prognostic Importance of Lactate and Blood Gas Parameters in Predicting Mortality in Patients with Critical Malignancies. ( Ak, E; Avci, A; Can, D; Erdur, A; Gurkan, TT; Guven, R, 2023) |
| "Sepsis is one of the most challenging health conditions worldwide, with relatively high incidence and mortality rates." | 1.91 | Frequent temporal patterns of physiological and biological biomarkers and their evolution in sepsis. ( Capan, M; Jazayeri, A; Yang, CC, 2023) |
| "Clinical sepsis was found to be associated with a lactate value above 2 mMol/L at postnatal 6th-hour venous blood gas (p = 0." | 1.91 | Evaluating of neonatal early onset sepsis through lactate and base excess monitoring. ( Gonen, I; Kaya, N; Perk, Y; Uygur, A; Vural, M; Yilmaz, A, 2023) |
| "Eighty-seven newborns diagnosed with neonatal sepsis at a neonatal intensive care unit between January 2010 and July 2021 were included in the study." | 1.91 | Can lactate be valuable in early diagnosis and prognosis of neonatal sepsis? ( Açıkalın, AA; Ergül, E; Gündoğan, E; Güven, D; Kislal, FM; Polat, CC; Sarıcı, D, 2023) |
| "Urosepsis is a disease with high mortality, and early diagnosis and treatment are important." | 1.91 | An analysis of lactate/albumin, procalcitonin/albumin, and blood urea nitrogen/albumin ratios as a predictor of mortality in uroseptic patients. ( Aslan, S; Bayrakçı, S; Şahin, A, 2023) |
| "Adult septic shock patients visiting the ED with 28-day survival after admission were included." | 1.72 | Prognostic factors for late death in septic shock survivors: a multi-center, prospective, registry-based observational study. ( Choi, SH; Chung, SP; Jo, YH; Kim, SM; Kim, WY; Lim, TH; Park, YS; Ryoo, SM; Shin, TG; Suh, GJ, 2022) |
| "The NLRP3 levels in the septic shock group was significantly higher (431." | 1.72 | Serum NLRP3: A biomarker for identifying high-risk septic patients. ( Huang, W; Liu, D; Wang, X; Xie, F; Zhang, H, 2022) |
| "Sepsis is a common cause of emergency department (ED) presentation and hospital admission, accounting for a disproportionate number of deaths each year relative to its incidence." | 1.72 | Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool. ( Caldwell, JR; Dahn, C; Jamin, C; Mandola, S; Tang, N; Warstadt, NM, 2022) |
| "Sepsis is a life-threating organ dysfunction caused by a dysregulated host response to infection." | 1.72 | A 2-year retrospective analysis of the prognostic value of MqSOFA compared to lactate, NEWS and qSOFA in patients with sepsis. ( Alfano, F; Caio, G; Catanese, EM; Contini, C; De Giorgi, A; De Giorgio, R; Gambuti, E; Guarino, M; Perna, B; Strada, A; Volpato, S, 2022) |
| "Sepsis is a host response with life-threatening organ dysfunction caused by an infection." | 1.72 | Risk stratification and prognostic value of serum neutrophil gelatinase-associated lipocalin (sNGAL) in sepsis patients. ( Fan, J; He, ZM; Sun, Y; Wu, Y; Yu, C; Zhang, W; Zhou, Y, 2022) |
| "Sepsis has high incidence and fatality rates in intensive care units, often leading to renal failure." | 1.72 | The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk factor of 28-day mortality in intensive care units. ( Han, D; Lyu, J; Wang, Z; Xu, F; Zhang, L, 2022) |
| "Validation of the host-mRNA infection severity classifier IMX-SEV-2." | 1.72 | Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department. ( Bauer, W; Bergström, WH; Buturovic, L; Diehl-Wiesenecker, E; Galtung, N; Kappert, K; Lehmann, D; Liesenfeld, O; Luethy, R; Markmann, N; Mayhew, M; Somasundaram, R; Sweeney, TE; Tauber, R; Wacker, J, 2022) |
| "Treatment with remifentanil reduced the expression of lactic acid, pyruvate, and epinephrine in the heart and kidney tissues and attenuated the expression of PDK4 messenger RNA and PDK4 protein in the myocardial tissue." | 1.72 | Remifentanil reduces multiple organ and energy metabolism disturbances in a rat sepsis model. ( Chen, X; Liao, XY; Lin, JD; Wu, Y; Wu, ZZ; Yang, MX; Zhang, BL, 2022) |
| "True bacteremia was detected in 899 (20." | 1.72 | Ability of lactate, procalcitonin, and criteria defining sepsis to predict 30-day mortality, bacteremia, and microbiologically confirmed infection in patients with infection suspicion treated in emergency departments. ( Beneyto Martín, P; Candel González, FJ; García-Lamberechts, EJ; González Del Castillo, J; Huarte Sanz, I; Julián-Jiménez, A; Navarro Bustos, C; Rubio-Díaz, R, 2022) |
| "Lactic acid and ATP were also tested." | 1.72 | WIN55212-2 alleviates acute lung injury by inhibiting macrophage glycolysis through the miR-29b-3p/FOXO3/PFKFB3 axis. ( Guo, H; He, Q; Yin, J; Zou, B, 2022) |
| "Severe hyperlactatemia was associated with death in the ICU (p < 0." | 1.72 | Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors. ( Claus, S; Fichtner-Feigl, S; Kousoulas, L; Lederer, AK; Runkel, M; Spiegelberg, J; Utzolino, S, 2022) |
| "Sepsis is a heterogeneous syndrome that results in life-threatening organ dysfunction." | 1.72 | Septic Shock: Phenotypes and Outcomes. ( Boucekine, M; Cereuil, A; Culver, A; Lefebvre, L; Leone, M; Papazian, L; Ronflé, R, 2022) |
| "Seventy-five patients with septic shock hospitalized in the emergency intensive care unit (EICU) of Hebei General Hospital from March 2020 to September 2021 were included, and the patients' baseline characteristics and laboratory findings were collected." | 1.72 | The value of NSE to predict ICU mortality in patients with septic shock: A prospective observational study. ( Cao, SM; Han, H; Li, JG; Li, LL; Lv, J; Xu, X; Zhang, LR; Zhang, LT, 2022) |
| "Lactic acid was injected i." | 1.72 | LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS. ( Fan, M; Gill, PS; Ha, T; Li, C; Tu, F; Wang, X; Williams, DL; Xu, J; Yang, K; Zhang, X, 2022) |
| "Sepsis and septic shock represent a significant worldwide mortality burden." | 1.72 | Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study. ( Cave, G; Chalmers, D; Greenberg, M; O'Beirn, S; Schneider, L, 2022) |
| "Sepsis is a leading cause of morbidity and mortality in hospitalized patients." | 1.72 | Machine learning models to predict in-hospital mortality in septic patients with diabetes. ( Dai, Z; Huang, D; Lei, J; Li, N; Liu, H; Qi, J; Sun, C; Zhou, K, 2022) |
| "Sepsis is a life-threatening condition and remains a major cause of mortality." | 1.72 | Clinical usefulness of biomarkers for diagnosis and prediction of prognosis in sepsis and septic shock. ( Jang, HJ; Jang, JH; Jo, KM; Kim, SH; Lee, HK; Lee, JH; No, TH; Park, JH, 2022) |
| "Sepsis was diagnosed according to Sepsis-3." | 1.62 | Changes in carbon dioxide production and oxygen uptake evaluated using indirect calorimetry in mechanically ventilated patients with sepsis. ( Asada, T; Doi, K; Hayase, N; Hirayama, I; Hiruma, T; Yamamoto, M, 2021) |
| "Septic shock was present at admission in 56." | 1.62 | Lactate Measurements and Their Association With Mortality in Pediatric Severe Sepsis in India: Evidence That 6-Hour Level Performs Best. ( Alam, A; Gupta, S, 2021) |
| "Sepsis is a common and lethal medical problem." | 1.62 | Clinical validation demonstrates concordance of qSOFA and POC lactate Bayesian model: Results from the ACDC Phase-2 program. ( Báez, AA; Cochón, L; Libell, N; López, O; Martínez, MDP; Nicolás, JM, 2021) |
| "We enrolled 66 patients with sepsis or septic shock and compared 14 blood-based biomarkers in the first 24 h after ICU admission." | 1.62 | Mortality prediction using a novel combination of biomarkers in the first day of sepsis in intensive care units. ( Bai, C; Chen, W; Deng, D; Li, B; Liu, J; Shan, A; Shi, F; Wang, J; Xie, M; Yao, C; Zhang, Y, 2021) |
| "Respiratory failure was the most frequently observed complication (106 [67." | 1.62 | Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak. ( Wang, Z, 2021) |
| "Sepsis is a life-threatening condition, and serum lactate levels have been used to predict patient prognosis." | 1.62 | The timing of last hemodialysis influences the prognostic value of serum lactate levels in predicting mortality of end-stage renal disease patients with sepsis in the emergency department. ( Chen, FC; Cheng, CY; Cheng, HH; Chu, CC; Su, CM; Te Kung, C, 2021) |
| "Sepsis was induced by cecal ligation and puncture and gluconeogenesis was assessed in liver perfusion." | 1.62 | Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis. ( Bertolini, GL; Biazi, GR; de Souza Galia, WB; de Souza, HM; Frasson-Uemura, IG; Miksza, DR; Zaia, CTBV; Zaia, DAM, 2021) |
| "Sepsis is a potentially lethal syndrome resulting from a maladaptive response to infection." | 1.62 | Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis. ( Carmeliet, P; De Bosscher, K; Dewaele, S; Dewerchin, M; Dewyse, L; Eggermont, M; Libert, C; Moita, LF; Nuyttens, L; Paakinaho, V; Palvimo, JJ; Sponholz, C; Timmermans, S; Van de Voorde, J; van Grunsven, LA; Van Looveren, K; Van Wyngene, L; Vancraeynest, L; Vanderhaeghen, T; Vandewalle, J; Velho, TR; Wallaeys, C; Weis, S, 2021) |
| "Thiamine is an essential co-factor for aerobic metabolism." | 1.56 | Thiamine status and lactate concentration in sepsis: A prospective observational study. ( Annane, D; Bounab, R; Chevret, S; Heming, N; Meng, P; Salah, A; Sivanandamoorthy, S, 2020) |
| "Sepsis is a complex disorder with very high morbidity and mortality; it can occur when an immune disorder triggers an invasion of pathogens in the host." | 1.56 | Inflammation-targeting polymeric nanoparticles deliver sparfloxacin and tacrolimus for combating acute lung sepsis. ( Ding, Y; Fan, B; Mao, Z; Wang, W; Wang, Y; Wu, J; Yang, Y, 2020) |
| "The new septic shock definition may be useful for identifying high-risk patients requiring intensive care." | 1.56 | A mortality analysis of septic shock, vasoplegic shock and cryptic shock classified by the third international consensus definitions (Sepsis-3). ( Jung, SK; Kang, HD; Kim, WY; Kim, YJ; Lee, YJ; Oh, SH; Sohn, CH; Yang, WS, 2020) |
| "Sepsis is a life-threatening disease in the intensive care unit (ICU)." | 1.56 | STAPLAg: a convenient early warning score for use in infected patients in the intensive care unit. ( Deng, Y; Gao, Y; Huang, Y; Lv, D; Xu, X; Zhang, K; Zhu, C, 2020) |
| "Sepsis is a significant public health crisis in the United States, contributing to 50% of inpatient hospital deaths." | 1.56 | Utilization of a multidisciplinary emergency department sepsis huddle to reduce time to antibiotics and improve SEP-1 compliance. ( Aaronson, EL; Benzer, TI; Black, L; Filbin, MR; Hayes, BD; Hibbert, KA; Kraus, C; Raja, AS; Sonis, JD; Temin, E; Vareschi, M; White, BA; Wilcox, SR, 2020) |
| "Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation." | 1.56 | Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis. ( Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG, 2020) |
| " Lactate dosage was performed at ED-HDU admission (T0), after 2 h (T2), 6 h (T6) and 24 h (T24); lactate clearance was calculated at T2 and T6 [T2: ((LAC T0-LAC T2/LAC T0)*100)]; T6: [(LAC T0-LAC T6/LAC T0)*100]." | 1.51 | Prognostic value of serial lactate levels in septic patients with and without shock. ( Caldi, F; Donnini, C; Giacomelli, I; Innocenti, F; Meo, F; Pini, R; Ralli, ML; Tassinari, I; Tozzi, C; Zanobetti, M, 2019) |
| " The secondary outcomes include the tumor necrosis factor α (TNF-α) counts, interleukin 6 (IL-6) counts, interleukin 10 (IL-10) counts, procalcitonin (PCT), lactic acid, the level of T cell subsets (CD3+, CD4+, CD8+, CD4+/CD8+), monocytes of human leukocyte antigen DR (HLA-DR), C-reactive protein (CRP), the numeration of leukocyte, intra-abdominal pressure, and adverse events or reactions." | 1.51 | Efficacy and safety of acupuncture as a complementary therapy for sepsis: A protocol of systematic review and meta-analysis. ( Tan, Q; Wang, J; Wang, L; Xian, J; Yu, H; Zhang, C; Zhang, X; Zhu, Y, 2019) |
| "The RR of hospital mortality of septic shock was 10." | 1.51 | Application of the new Sepsis-3 definition in a cohort of patients with severe sepsis and septic shock admitted to Intensive Care Unit from the Emergency Department. ( García-Gigorro, R; Molina-Collado, Z; Montejo González, JC; Sáez-de la Fuente, I; Sanchez-Izquierdo, JÁ, 2019) |
| "Maternal sepsis is a significant cause of maternal morbidity and mortality and is a preventable cause of maternal death." | 1.51 | SMFM Consult Series #47: Sepsis during pregnancy and the puerperium. ( Louis, JM; Pacheco, LD; Plante, LA, 2019) |
| "Sepsis is one of the leading causes of death globally, with significant associated costs." | 1.51 | Does Gender Matter in Septic Patient Outcomes? ( Bush, R; Connelly, CD; Ecoff, L; Failla, KR; Macauley, K, 2019) |
| "Sepsis is a common critical condition caused by the body's overwhelming response to certain infective agents." | 1.51 | Prognostic accuracy of the serum lactate level, the SOFA score and the qSOFA score for mortality among adults with Sepsis. ( Gou, S; Li, Y; Liu, Z; Meng, Z; Wu, H; Wu, S; Zhao, J, 2019) |
| "Sepsis is a systemic inflammatory response syndrome resulting from infection." | 1.51 | MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway. ( Bai, YP; Li, J; Li, TM; Liu, L; Liu, XR; Tang, N; Wang, XB, 2019) |
| "Background Sepsis is the overwhelming host response to infection leading to shock and multiple organ dysfunction." | 1.51 | Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice. ( Bauer, M; Bonios, MJ; de Lucia, C; Drosatos, K; Hoffman, M; Koch, WJ; Kyriazis, ID; Lucchese, AM; Piedepalumbo, M; Schulze, PC, 2019) |
| "The incidence of nonocclusive mesenteric ischemia was particularly high." | 1.51 | Prognostic factors of acute mesenteric ischemia in ICU patients. ( Caluwaerts, M; Castanares-Zapatero, D; Hantson, P; Laterre, PF, 2019) |
| "Sepsis has a well-studied inflammatory phase, with a less-understood secondary immunosuppressive phase." | 1.51 | Lactic Acid Inhibits Lipopolysaccharide-Induced Mast Cell Function by Limiting Glycolysis and ATP Availability. ( Abdul Qayum, A; Abebayehu, D; Barnstein, BO; Caslin, HL; Chalfant, CE; Haque, TT; Hoeferlin, LA; Paez, PA; Pondicherry, N; Ryan, JJ; Taruselli, MT, 2019) |
| "Clear definitions for septic shock assist clinicians regarding recognition, treatment and standardized reporting of characteristics and outcome of this entity." | 1.48 | The influence of a change in septic shock definitions on intensive care epidemiology and outcome: comparison of sepsis-2 and sepsis-3 definitions. ( Driessen, RGH; Mol, MF; Schnabel, RM; van de Poll, MCG; van Mook, WNKA, 2018) |
| "Sepsis is a potentially fatal condition with high treatment costs, and is especially common among the elderly population." | 1.48 | Effect of platelet-lymphocyte ratio and lactate levels obtained on mortality with sepsis and septic shock. ( Biyikli, E; Kavalci, C; Kayipmaz, AE, 2018) |
| "From 5,072 patients with severe sepsis or septic shock, 1,412 (27." | 1.48 | Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock. ( Delaney, CW; Hoff, A; Kumar, V; Pruinelli, L; Simon, G; Steinbach, M; Westra, BL; Yadav, P, 2018) |
| "Our primary outcome was critical illness, defined as one or more of the composite outcomes of death, vasopressor use or intensive care unit (ICU) admission within 72 hours of presentation." | 1.48 | Comparison of qSOFA with current emergency department tools for screening of patients with sepsis for critical illness. ( Baumann, BM; Darger, B; Fernandez, D; Greenwood, JC; Jung, SY; Kilgannon, JH; Nuckton, TJ; Rodriguez, RM; Shofer, FS; Speich, KG; Troeger, D; Valencia, J, 2018) |
| "Systemic inflammatory response syndrome was also recorded." | 1.48 | Predictive Validity of Sepsis-3 Definitions and Sepsis Outcomes in Critically Ill Patients: A Cohort Study in 49 ICUs in Argentina. ( Díaz, A; Dubin, A; Estenssoro, E; Kanoore Edul, VS; Klein, F; Lattanzio, B; Loudet, CI; Osatnik, J; Pálizas, F; Piezny, D; Pozo, MO; Ríos, FG; Rubatto Birri, PN; Santamaría, A; Tuhay, G; Vázquez, DN; Zakalik, G, 2018) |
| "In cases of Polytrauma induced sepsis or septic shock, the level started to increase within first 72 hours after traumatic injury, pick concentration was achieved within first 25 days high from the beginning and dynamically increases within first 25 days, the tendency of gradual decrease was seen after 30 days." | 1.48 | THE ROLE OF PROCALCITONIN AND BLOOD LACTIC ACID VALUES IN PROGNOSIS OF SEPSIS AND SEPTIC SHOCK IN POLYTRAUMA PATIENTS. ( Kanashvili, B; Ratiani, L; Saganelidze, K, 2018) |
| "in patients with sepsis and septic shock, achievement of lactate clearance and ScvO2 targets associates with similar early mortality risk compared to achievement of lactate clearance target only." | 1.48 | Comparison of Survival Prediction with Single versus Combination Use of Microcirculation End Point Resuscitation in Sepsis and Septic Shock. ( Sinto, R; Suwarto, S; Widodo, D, 2018) |
| "Sepsis is a common condition in the emergency department (ED)." | 1.48 | Lactate - Arterial and Venous Agreement in Sepsis: a prospective observational study. ( Datta, D; Graham, C; Grahamslaw, J; Gray, AJ; Walker, CA, 2018) |
| "Prognostication in sepsis is limited by disease heterogeneity, and measures to risk-stratify patients in the proximal phases of care lack simplicity and accuracy." | 1.48 | Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department. ( Aydin, A; Dziura, JD; Reynolds, J; Swenson, KE; Wira, CR, 2018) |
| "no sepsis), and prediction of severe sepsis or septic shock (vs." | 1.46 | Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients. ( Baumann, NA; Block, DR; Bryant, SC; Clements, CM; Karon, BS; Tolan, NV; Wockenfus, AM, 2017) |
| "Patients with severe sepsis who experience rapid, early deterioration and death are of particular concern." | 1.46 | Clinical predictors of early death from sepsis. ( Bowman, J; Guirgis, FW; Javed, A; Jones, AE; Puskarich, MA; Robinson, T; Sterling, SA, 2017) |
| "The ability of MOx to detect even mild septic shock has meaningful implications for emergency care, where decisions about triage and therapy must be made quickly and accurately." | 1.46 | Muscle oxygenation as an indicator of shock severity in patients with suspected severe sepsis or septic shock. ( Arakaki, LSL; Asplund, KM; Bulger, EM; Carlbom, DJ; Ciesielski, WA; Fisk, DM; Schenkman, KA; Shaver, JM; Sheehan, KL, 2017) |
| "Sepsis is a major public health problem as well as one of the leading causes of preventable death in children because of failure to recognise the early signs and symptoms and to resuscitate rapidly." | 1.46 | Importance of measuring lactate levels in children with sepsis. ( Anil, N, 2017) |
| "We performed a post hoc analysis of 513 septic shock patients with admission blood lactate measurements in the prospective, observational, multicenter FINNAKI study." | 1.46 | Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the FINNAKI Study. ( Jakob, SM; Karlsson, S; Perner, A; Pettilä, V; Poukkanen, M; Takala, J; Varis, E; Wilkman, E, 2017) |
| "Sensitivity and specificity are different between these parameters." | 1.46 | Absolute lactate value vs relative reduction as a predictor of mortality in severe sepsis and septic shock. ( Andersen, LW; Cocchi, MN; Donnino, MW; Lokhandwala, S; Nair, S; Patel, P, 2017) |
| "Fatal ketoacidosis due to diabetes mellitus, alcoholism, and starvation may produce characteristic basal vacuolization of renal tubular epithelial cells (RTEC)." | 1.46 | Septic Ketoacidosis-A Potentially Lethal Entity with Renal Tubular Epithelial Vacuolization. ( Byard, RW; Zhou, C, 2017) |
| "In children treated for sepsis in the emergency department, lactate levels greater than 36 mg/dL were associated with mortality but had a low sensitivity." | 1.46 | Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children. ( Bajaj, L; Brou, L; Deakyne, SJ; Fairclough, DL; Kempe, A; Scott, HF, 2017) |
| "Hyperlactatemia was associated with death in the ICU [odds ratio 1." | 1.43 | Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients. ( Fuhrmann, V; Haas, SA; Kluge, S; Lange, T; Metschke, M; Petzoldt, M; Saugel, B, 2016) |
| "We enrolled 411 adult patients with severe sepsis and lactate ≥4." | 1.43 | Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department. ( Agarwal, A; Drumheller, BC; Gaieski, DF; Goyal, M; Mikkelsen, ME; Sante, SC; Weber, AL, 2016) |
| "We enrolled adult patients in septic shock and with an elevated lactate (>3 mmol/L)." | 1.43 | Cytochrome C in Patients with Septic Shock. ( Andersen, LW; Balkema, JL; Berg, KM; Chase, M; Cocchi, MN; Donnino, MW; Gazmuri, RJ; Holmberg, MJ; Liu, X; Montissol, S; Sulmonte, C, 2016) |
| "Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in clinical criteria for sepsis." | 1.43 | Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). ( Angus, DC; Brunkhorst, FM; Deutschman, CS; Escobar, GJ; Iwashyna, TJ; Kahn, JM; Liu, VX; Rea, TD; Rubenfeld, G; Scherag, A; Seymour, CW; Shankar-Hari, M; Singer, M, 2016) |
| "The acute phase of sepsis is characterized by a strong inflammatory reaction." | 1.43 | Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. ( Arts, RJ; Bonten, MJ; Cheng, SC; Cremer, OL; Giamarellos-Bourboulis, EJ; Gresnigt, MS; Joosten, LA; Kox, M; Lachmandas, E; Leentjens, J; Manjeri, GR; Netea, MG; Pickkers, P; Schultz, MJ; Scicluna, BP; van de Veerdonk, FL; van der Meer, AJ; van der Poll, T; Wagenaars, JA; Willems, PH, 2016) |
| "During resuscitation in severe sepsis and septic shock, several goals are set." | 1.43 | The association between lactate, mean arterial pressure, central venous oxygen saturation and peripheral temperature and mortality in severe sepsis: a retrospective cohort analysis. ( Bosman, RJ; Houwink, AP; Rijkenberg, S; van der Voort, PH, 2016) |
| "To investigate the prognostic significance of venous-to-arterial carbon dioxide difference to arteriovenous oxygen content difference ratio (Pv-aCO2/Ca-vO2 ratio) combined with lactate in patients with septic shock during the early phases of resuscitation." | 1.43 | [Venous-to-arterial carbon dioxide difference to arteriovenous oxygen content difference ratio combined with lactate to predict prognosis of patients with septic shock]. ( Dai, HW; Gong, SJ; Li, L; Song, J; Wang, MJ; Xu, QH; Yan, J; Yu, YH; Zhou, JD, 2016) |
| "Endothelial damage developing in severe sepsis or septic shock results in multiorgan dysfunction." | 1.42 | Clinical significance of circulating endothelial cells in patients with severe sepsis or septic shock. ( Hong, SB; Huh, JW; Koh, Y; Lim, CM; Moon, JY; Yoo, JW, 2015) |
| "A total of 50 patients with sepsis, severe sepsis or septic shock were included." | 1.42 | Prospective evaluation of regional oxygen saturation to estimate central venous saturation in sepsis. ( Hecker, A; Koch, C; Lichtenstern, C; Monz, T; Röhrig, R; Schneck, E; Uhle, F; Weigand, MA, 2015) |
| "A total of 80 cases of severe sepsis patients with MODS treated at our center from 2011 January to 2013 October were selected and assigned to receive CHVHF (n = 42) and continuous volume hemofiltration (CVHF, n = 38)." | 1.42 | [Efficacies of continuous high volume hemofiltration in severe sepsis patients with multiple organ dysfunction syndrome]. ( Cai, H; Du, C; Shao, S; Yan, Q, 2015) |
| "To discuss the risk factors of acute respiratory distress syndrome (ARDS) in patients with sepsis in emergency department." | 1.42 | [Analysis of the risk factors of acute respiratory distress syndrome of Berlin new definition in patients with sepsis in emergency department]. ( Liu, Z; Qiao, L, 2015) |
| "Patients with severe sepsis/septic shock who were screened or contacted by a medical emergency team between January 2012 and August 2012 were enrolled at a university-affiliated hospital with ~2,700 beds, including 28 medical ICU beds." | 1.42 | A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock. ( Choi, SH; Hong, SB; Huh, JW; Jung, YK; Kang, BJ; Koh, Y; Lee, JR; Lim, CM; Park, TS; Son, JS; Yoo, JW, 2015) |
| "For other groups, severe sepsis was induced by CLP." | 1.42 | Shenfu injection alleviates intestine epithelial damage in septic rats. ( Chen, Z; Huang, L; Jiang, R; Lei, S; Wang, L; Wu, Y; Xia, G; Xing, X; Zhi, Y; Zhu, M, 2015) |
| "Sepsis is a lethal and complex clinical syndrome caused by infection or suspected infection." | 1.42 | The Cold-Inducible RNA-Binding Protein (CIRP) Level in Peripheral Blood Predicts Sepsis Outcome. ( Dong, H; Huang, J; Li, J; Lv, J; Zhong, Y; Zhou, Y, 2015) |
| "Patients with severe sepsis and septic shock are at high risk for development of pulmonary complications, including acute respiratory distress syndrome (ARDS)." | 1.42 | Sepsis-associated pulmonary complications in emergency department patients monitored with serial lactate: An observational cohort study. ( Dettmer, MR; Fuller, BM; Mohr, NM, 2015) |
| "Two hundred sixty patients with severe sepsis or septic shock were included." | 1.42 | Long-Term β-Blocker Therapy Decreases Blood Lactate Concentration in Severely Septic Patients. ( Contenti, J; Corraze, H; Lemoël, F; Levraut, J; Occelli, C, 2015) |
| "Different animal models of experimental lung injury have been used to investigate mechanisms of lung injury." | 1.42 | Time- and dose-dependent severity of lung injury in a rat model of sepsis. ( Azamfirei, L; Cioc, AD; Copotoiu, SM; Cotoi, OS; Fodor, P; Fodor, RŞ; Georgescu, AM; Grigorescu, BL, 2015) |
| "In patients with severe SIRS and severe sepsis, simultaneously measured ScvO(2) and lactate levels showed no correlation, and normalization of lactate levels within 48 h was a predictive factor for survival." | 1.40 | Prognostic value of central venous oxygen saturation and blood lactate levels measured simultaneously in the same patients with severe systemic inflammatory response syndrome and severe sepsis. ( Han, SK; Kim, YW; Lee, CH; Lee, J; Lee, SM; Park, JH; Park, YS; Yim, JJ; Yoo, CG, 2014) |
| "665 adult patients with severe sepsis admitted from May 2011 to December 2012 in ED were found to be eligible for the study." | 1.40 | [The value of combination of the mortality in emergency department sepsis score and blood lactate level in the risk stratification of severe sepsis in the emergency department]. ( Tan, D; Xia, Z; Zheng, A; Zhou, C, 2014) |
| "Sepsis was defined as suspected infection plus two or more systemic inflammatory response syndrome (SIRS) criteria; those with hypotension were excluded." | 1.40 | The microcirculation is preserved in emergency department low-acuity sepsis patients without hypotension. ( Barche, A; Bracey, A; Chang, Y; Filbin, MR; Hou, PC; Kao, E; Massey, M; Shapiro, NI; Skibsted, S, 2014) |
| "sixty patients with diabetic ketoacidosis were enrolled in the study; in which 24 (40%) patients were died within 5 days after admission." | 1.40 | Predictors of five days mortality in diabetic ketoacidosis patients: a prospective cohort study. ( Pohan, HT; Sutrisna, B; Suwarto, S; Waspadji, S, 2014) |
| "Severe sepsis and septic shock are associated with high mortality." | 1.40 | Therapeutic goal achievements during severe sepsis and septic shock resuscitation and their association with patients' outcomes. ( Permpikul, C; Sringam, P; Tongyoo, S, 2014) |
| ""Cryptic shock" was defined as severe sepsis with a lactate level of 4 mmol/L or greater and normotension, "COS" was defined as initial CS that progressed to septic shock within 72 h, and "OS" was defined as septic shock on ED arrival." | 1.40 | Association between hemodynamic presentation and outcome in sepsis patients. ( Cha, WC; Hwang, SY; Jeon, K; Jeong, YK; Jo, IJ; Lee, TR; Shin, TG; Sim, MS; Song, KJ; Suh, GY, 2014) |
| "Neutropenia is a common chemotherapy-derived complication in cancer patients, in whom the prevalence of sepsis ranges from 12." | 1.40 | [Serum lactate as a biomarker of severe sepsis in children with cancer, neutropenia and fever]. ( Huelgas-Plaza, AC; Miranda-Novales, MG; Pacheco-Rosas, DO, 2014) |
| "Eighty-seven consecutive patients with severe sepsis, including 35 with MV, were evaluated." | 1.40 | Serum adhesion molecules as outcome predictors in adult severe sepsis patients requiring mechanical ventilation in the emergency department. ( Chang, HW; Chang, WN; Chang, YT; Cheng, BC; Cheng, HH; Chiang, YF; Hsiao, SY; Huang, CC; Kung, CT; Lin, WC; Lu, CH; Su, CM; Su, YJ; Tsai, NW; Tsai, TC; Wang, HC, 2014) |
| "Early recognition and treatment of sepsis improves outcomes." | 1.40 | ED bedside point-of-care lactate in patients with suspected sepsis is associated with reduced time to iv fluids and mortality. ( LeBlanc, D; Singer, AJ; Taylor, M; Thode, HC; Williams, J, 2014) |
| "The objective was to determine the diagnostic characteristics of a clinical screening tool in combination with measuring early bedside point-of-care (POC) lactate levels in emergency department (ED) patients with suspected sepsis." | 1.40 | Diagnostic characteristics of a clinical screening tool in combination with measuring bedside lactate level in emergency department patients with suspected sepsis. ( Domingo, A; Ghazipura, S; Khorasonchi, A; Shapiro, NI; Singer, AJ; Taylor, M; Thode, HC, 2014) |
| "Sepsis is a serious worldwide health care condition that is associated with high mortality rates, despite improvements in the ability to manage infection." | 1.39 | Implications of the new international sepsis guidelines for nursing care. ( Aitken, L; Kleinpell, R; Schorr, CA, 2013) |
| "To study the prognostic value of arterial lactate combined with base excess (BE) in sepsis patients." | 1.39 | [Prognostic value of arterial lactate content combined with base excess in patients with sepsis: a retrospective study]. ( Cui, YL; Diao, MY; Lin, ZF; Wang, T, 2013) |
| "Acute respiratory distress syndrome was defined using the Berlin definition." | 1.39 | The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. ( Bellamy, SL; Christie, JD; Fuchs, BD; Gaieski, DF; Goyal, M; Lyon, S; Meyer, NJ; Mikkelsen, ME; Miltiades, AN; Shah, CV, 2013) |
| "Patients with severe sepsis without shock or tissue hypoperfusion face substantial mortality; however, treatment guidelines are lacking." | 1.39 | Fluid volume, lactate values, and mortality in sepsis patients with intermediate lactate values. ( Escobar, GJ; Liu, V; Morehouse, JW; Soule, J; Whippy, A, 2013) |
| "We identified 423 patients with severe sepsis and electronically recorded continuous hemodynamic data in the prospective observational FINNAKI study." | 1.39 | Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study. ( Hautamäki, R; Hovilehto, S; Inkinen, O; Karlsson, S; Kaukonen, KM; Korhonen, AM; Kuitunen, A; Laru-Sompa, R; Pettilä, V; Poukkanen, M; Uusaro, A; Vaara, ST; Wilkman, E, 2013) |
| "Severe sepsis is a condition with a high mortality rate, and the majority of patients are first seen by Emergency Medical Services (EMS) personnel." | 1.39 | Early detection and treatment of patients with severe sepsis by prehospital personnel. ( Clouatre, AE; Guerra, WF; Mayfield, TR; Meyers, MS; Riccio, JC, 2013) |
| "Patients with severe sepsis and with high serum lactate levels (≥ 4 mmol/L) constitute a potential risk group that may benefit from more aggressive treatment." | 1.38 | Serum lactate is a useful predictor of death in severe sepsis in patients with pemphigus vulgaris. ( Montes de Oca-Sánchez, G; Ponce-Olivera, RM; Tirado-Sánchez, A; Vázquez-González, D, 2012) |
| "Patients with septic shock state prior to initial presentation has a lower 30 day survival compared to any other septic conditions." | 1.38 | The use of laboratory and physiological parameters in predicting mortality in sepsis induced hypotension and septic shock patients attending the emergency department. ( Azlan, K; Hisamuddin, NA, 2012) |
| "Despite treatment, this syndrome complicated the interpretation of blood glucose readings as a measure of islet graft function and resulted in death or the need for euthanasia in all seven animals." | 1.38 | A syndrome of severe hypoglycemia and acidosis in young immunosuppressed diabetic monkeys and pigs-association with sepsis. ( Bottino, R; Cooper, DK; Dons, EM; Echeverri, GJ; Rigatti, LH; van der Windt, DJ; Wagner, R; Wijkstrom, M; Zhou, H, 2012) |
| "Sepsis was induced by intravenous administration of E." | 1.37 | A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis. ( Ferko, A; Havel, E; Hyspler, R; Koci, J; Lochman, P; Oberreiter, M; Ticha, A; Valis, M, 2011) |
| "Sepsis is a serious complication for patients with obstructive jaundice." | 1.36 | Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats. ( Wang, P; Wu, R; Yang, J; Zhou, M, 2010) |
| "Early recognition and treatment in severe sepsis improve outcomes." | 1.36 | Out-of-hospital characteristics and care of patients with severe sepsis: a cohort study. ( Band, RA; Cooke, CR; Gaieski, DF; Goss, CH; Hylton, J; Mikkelsen, ME; Rea, TD; Seymour, CW, 2010) |
| "Forty-four patients with severe sepsis were enrolled." | 1.36 | Skin collagen synthesis is depressed in patients with severe sepsis. ( Ala-Kokko, T; Gäddnäs, FP; Koivukangas, V; Koskela, M; Laurila, J; Oikarinen, A; Risteli, J; Saarnio, J, 2010) |
| "During septic shock, muscle produces lactate and pyruvate by way of an exaggerated Na(+), K(+)-ATPase-stimulated aerobic glycolysis associated with epinephrine stimulation." | 1.36 | Increased muscle-to-serum lactate gradient predicts progression towards septic shock in septic patients. ( Gerard, A; Gibot, S; Levy, B; Perez, P, 2010) |
| "A total of 1757 consecutive trauma patients with an Injury Severity Score (ISS) > 16 admitted over a 10-year period were retrospectively analyzed over a 21-day period." | 1.35 | Early serum procalcitonin, interleukin-6, and 24-hour lactate clearance: useful indicators of septic infections in severely traumatized patients. ( Billeter, A; Keel, M; Mica, L; Seifert, B; Stocker, R; Turina, M, 2009) |
| "This group of patients is those with severe sepsis and septic shock and they could also benefit greatly from timely prehospital care." | 1.35 | Sepsis: a need for prehospital intervention? ( Daniels, R; Nutbeam, T; Robson, W, 2009) |
| "During septic shock, muscle produces lactate by way of an exaggerated NaK-adenosine triphosphatase (ATPase)-stimulated aerobic glycolysis associated with epinephrine stimulation possibly through beta2 adrenoreceptor involvement." | 1.35 | Increased aerobic glycolysis through beta2 stimulation is a common mechanism involved in lactate formation during shock states. ( Desebbe, O; Gibot, S; Levy, B; Montemont, C, 2008) |
| "We enrolled 10 patients with severe sepsis and 9 healthy age-matched volunteers." | 1.34 | Dynamic near-infrared spectroscopy measurements in patients with severe sepsis. ( Beilman, GJ; Mulier, KE; Myers, DE; Skarda, DE; Taylor, JH, 2007) |
| "Sepsis is a major clinical challenge that is associated with encephalopathy and multi-organ dysfunction." | 1.34 | Caecal ligation and puncture in the rat mimics the pathophysiological changes in human sepsis and causes multi-organ dysfunction. ( Andrews, PL; Brooks, HF; Davies, DC; Moss, RF; Osabutey, CK, 2007) |
| "Seven patients with severe sepsis or septic shock, seven patients with cardiogenic shock, and seven healthy volunteers." | 1.33 | Lactate and glucose metabolism in severe sepsis and cardiogenic shock. ( Berger, MM; Bollmann, M; Cayeux, MC; Chioléro, RL; Martinez, A; Revelly, JP; Tappy, L, 2005) |
| "Infection and sepsis have a close relationship with bacterial translocation." | 1.33 | [Clinical study on bacterial translocation in severe multiple trauma patients]. ( Deng, Q; Li, JY; Li, ZL; Lin, HY; Lu, LR; Lü, Y; Qiao, Z, 2006) |
| "In our study, the mortality of severe sepsis and septic shock patients was 38%." | 1.33 | Evolutive standard base excess and serum lactate level in severe sepsis and septic shock patients resuscitated with early goal-directed therapy: still outcome markers? ( Azevedo, LC; da Cruz Neto, LM; Maciel, AT; Noritomi, DT; Park, M; Pizzo, VR, 2006) |
| "Critically ill patients treated for multiple organ failure often develop muscle dysfunction." | 1.33 | Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure. ( Fredriksson, K; Hammarqvist, F; Hultenby, K; Ljungqvist, O; Rooyackers, O; Strigård, K; Wernerman, J, 2006) |
| "Nine patients with septic shock and abdominal focus of infection, 7 with severe sepsis and pulmonary focus and 8 healthy subjects." | 1.33 | Increased colorectal permeability in patients with severe sepsis and septic shock. ( Espersen, K; Jørgensen, VL; Nielsen, SL; Perner, A, 2006) |
| "In patients with severe sepsis and septic shock, luminal concentrations of L- and D-lactate in the rectum were related to severity of disease and outcome." | 1.33 | Luminal concentrations of L- and D-lactate in the rectum may relate to severity of disease and outcome in septic patients. ( Jørgensen, VL; Perner, A; Reiter, N, 2006) |
| "Recent findings in human septic shock suggest that glucocorticosteroids can limit and even reverse hemodynamic disturbances and dependence on catecholamines." | 1.32 | Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock. ( Bollaert, PE; Levy, B; Longrois, D; Mallié, JP; Mansart, A; Seguin, C, 2003) |
| "Fifty-six patients with severe sepsis and blood lactate concentration <3 mmol/L." | 1.32 | Low exogenous lactate clearance as an early predictor of mortality in normolactatemic critically ill septic patients. ( Ciebiera, JP; Grimaud, D; Ichai, C; Levraut, J; Perus, O; Petit, I, 2003) |
| "Twenty-one patients had severe sepsis or septic shock." | 1.32 | Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients. ( Bankov, A; Marik, PE, 2003) |
| "The mechanism of gut injury in endotoxic shock seems unrelated to hypoxia and release of nitric oxide." | 1.32 | Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia. ( De Backer, D; Dimopoulos, G; Lobo, SM; Nagy, N; Preiser, JC; Sun, Q; Terzi, RG; Tu, Z; Vercruy, V; Vincent, JL; Vray, B, 2003) |
| "D-xylose content was increased at I/R1 and I/RL groups (both P<0." | 1.32 | [Change in intestinal function in sepsis in rat]. ( Hu, S; Jiang, XG; Jin, H; Li, JY; Lu, Y; Sheng, ZY; Sun, D, 2004) |
| "Sepsis was induced in 15 pigs by intraperitoneal instillation of a suspension of cecal content (1 g/kg animal body weight) and a toxinogenic Escherichia coli solution (2 x 10(11) colony-forming units)." | 1.31 | Early immunoneutralization of calcitonin precursors attenuates the adverse physiologic response to sepsis in pigs. ( Becker, KL; Martinez, JM; Müller, B; Nylén, ES; Snider, RH; Vath, SD; Wagner, KE; White, JC, 2002) |
| "We induced hemorrhagic shock by removing a sufficient quantity of blood to maintain a mean arterial pressure of 50 mm Hg or less for 120 min." | 1.31 | The effects of interleukin-10 in hemorrhagic shock. ( Cook, JW; Hinds, M; Karakozis, S; Kim, D; Kirkpatrick, JR; Provido, H, 2000) |
| "The incidence of disseminated intravascular coagulation (DIC) was significantly higher in the nonsurvivors than in the survivors." | 1.31 | Serial measurement of arterial lactate concentrations as a prognostic indicator in relation to the incidence of disseminated intravascular coagulation in patients with systemic inflammatory response syndrome. ( Gando, S; Kemmotsu, O; Kobayashi, S; Morimoto, Y; Nanzaki, S, 2001) |
| "The purpose of this study was to determine the physiologic variables that predict major adverse events in children in the intensive care unit after cardiac operations." | 1.30 | Early markers of major adverse events in children after cardiac operations. ( Butt, W; Duke, T; Karl, TR; South, M, 1997) |
| " coli dosage (1 x 10(10) E." | 1.30 | Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis. ( Burchardi, H; Goldmann, K; Götze, O; Höpken, U; Mathes, C; Mohr, M; Oppermann, M; Siever, S, 1998) |
| "Urea production was increased by alanine to a greater extent in the septic group compared to sham." | 1.29 | Hormone effects on hepatic substrate preference in sepsis. ( Clemens, MG; Paidas, CN, 1994) |
| " An attempt to analyze the ED50 of the three dose-response curves was inconclusive." | 1.28 | Hepatic insulin resistance during canine sepsis. ( Law, WR; McLane, MP; Raymond, RM; Tomasik, TW, 1991) |
| " In septic rats, the dose-response curve for the insulin-induced increment in glucose utilization was shifted downward and to the right." | 1.28 | In vivo insulin resistance during nonlethal hypermetabolic sepsis. ( Dobrescu, C; Lang, CH, 1989) |
| "Sepsis was induced in chronically catheterized conscious rats by multiple injections of live Escherichia coli via a subcutaneous catheter." | 1.27 | Inhibition of eicosanoid production by BW755C does not attenuate sepsis-induced alterations in glucose kinetics. ( Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ, 1987) |
| "Treatment with indomethacin prevented the 1-2 degrees C increase in body temperature observed in septic animals." | 1.27 | Fever is not responsible for the elevated glucose kinetics in sepsis. ( Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ, 1987) |
| "Many patients with adult respiratory distress syndrome exhibit supply dependence of VO2 even at high levels of QO2, which suggests that a peripheral O2 extraction defect may be present." | 1.27 | Pathological supply dependence of O2 uptake during bacteremia in dogs. ( Beyer, C; Nelson, DP; Samsel, RW; Schumacker, PT; Wood, LD, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (2.48) | 18.7374 |
| 1990's | 41 (6.77) | 18.2507 |
| 2000's | 79 (13.04) | 29.6817 |
| 2010's | 269 (44.39) | 24.3611 |
| 2020's | 202 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Arina, P | 1 |
| Moro, V | 1 |
| Baso, B | 1 |
| Baxter-Derrington, C | 1 |
| Singer, M | 2 |
| Weinberger, J | 1 |
| Klompas, M | 5 |
| Rhee, C | 3 |
| Kim, SM | 1 |
| Ryoo, SM | 3 |
| Shin, TG | 8 |
| Park, YS | 2 |
| Jo, YH | 3 |
| Lim, TH | 3 |
| Chung, SP | 3 |
| Choi, SH | 5 |
| Suh, GJ | 3 |
| Kim, WY | 5 |
| Evans, L | 2 |
| Rhodes, A | 3 |
| Alhazzani, W | 3 |
| Antonelli, M | 3 |
| Coopersmith, CM | 3 |
| French, C | 2 |
| Machado, FR | 3 |
| Mcintyre, L | 2 |
| Ostermann, M | 2 |
| Prescott, HC | 2 |
| Schorr, C | 4 |
| Simpson, S | 2 |
| Wiersinga, WJ | 1 |
| Alshamsi, F | 2 |
| Angus, DC | 4 |
| Arabi, Y | 2 |
| Azevedo, L | 2 |
| Beale, R | 2 |
| Beilman, G | 2 |
| Belley-Cote, E | 2 |
| Burry, L | 2 |
| Cecconi, M | 2 |
| Centofanti, J | 2 |
| Coz Yataco, A | 1 |
| De Waele, J | 2 |
| Dellinger, RP | 6 |
| Doi, K | 4 |
| Du, B | 2 |
| Estenssoro, E | 4 |
| Ferrer, R | 2 |
| Gomersall, C | 2 |
| Hodgson, C | 2 |
| Hylander Møller, M | 1 |
| Iwashyna, T | 2 |
| Jacob, S | 2 |
| Kleinpell, R | 3 |
| Koh, Y | 4 |
| Kumar, A | 4 |
| Kwizera, A | 2 |
| Lobo, S | 2 |
| Masur, H | 2 |
| McGloughlin, S | 3 |
| Mehta, S | 2 |
| Mehta, Y | 2 |
| Mer, M | 2 |
| Nunnally, M | 2 |
| Oczkowski, S | 2 |
| Osborn, T | 2 |
| Papathanassoglou, E | 2 |
| Perner, A | 5 |
| Puskarich, M | 2 |
| Roberts, J | 2 |
| Schweickert, W | 2 |
| Seckel, M | 2 |
| Sevransky, J | 2 |
| Sprung, CL | 3 |
| Welte, T | 2 |
| Zimmerman, J | 2 |
| Levy, M | 3 |
| Sauer, CM | 1 |
| Gómez, J | 1 |
| Botella, MR | 1 |
| Ziehr, DR | 1 |
| Oldham, WM | 1 |
| Gavidia, G | 1 |
| Rodríguez, A | 2 |
| Elbers, P | 1 |
| Girbes, A | 1 |
| Bodi, M | 1 |
| Celi, LA | 1 |
| Huang, W | 3 |
| Wang, X | 20 |
| Xie, F | 2 |
| Zhang, H | 9 |
| Liu, D | 10 |
| Joost Wiersinga, W | 1 |
| Yataco, AC | 2 |
| Møller, MH | 2 |
| Liu, DH | 1 |
| Ning, YL | 1 |
| Lei, YY | 1 |
| Chen, J | 3 |
| Liu, YY | 1 |
| Lin, XF | 1 |
| Yang, ZQ | 1 |
| Xian, SX | 1 |
| Chen, WT | 1 |
| Hao, X | 1 |
| Guo, D | 1 |
| Yuan, X | 2 |
| Xu, B | 1 |
| Jeon, SY | 1 |
| Ryu, S | 1 |
| Oh, SK | 1 |
| Park, JS | 2 |
| You, YH | 1 |
| Jeong, WJ | 1 |
| Cho, YC | 1 |
| Ahn, HJ | 1 |
| Kang, CS | 1 |
| Sugimoto, M | 1 |
| Takayama, W | 1 |
| Murata, K | 1 |
| Otomo, Y | 1 |
| Sheng, Y | 1 |
| Zheng, WL | 1 |
| Shi, QF | 1 |
| Zhang, BY | 1 |
| Yang, GY | 1 |
| Hirayama, I | 1 |
| Asada, T | 2 |
| Yamamoto, M | 1 |
| Hayase, N | 2 |
| Hiruma, T | 1 |
| Byler, S | 1 |
| Baker, A | 1 |
| Freiman, E | 1 |
| Herigon, JC | 1 |
| Eisenberg, MA | 1 |
| Baishya, N | 2 |
| Mamouei, M | 2 |
| Budidha, K | 2 |
| Qassem, M | 2 |
| Vadgama, P | 2 |
| Kyriacou, PA | 2 |
| Yu, T | 1 |
| Wang, R | 4 |
| Kadri, SS | 1 |
| Fram, D | 1 |
| Chen, HC | 1 |
| D Somogyi, R | 1 |
| C Sheridan, D | 1 |
| Warstadt, NM | 1 |
| Caldwell, JR | 1 |
| Tang, N | 2 |
| Mandola, S | 1 |
| Jamin, C | 1 |
| Dahn, C | 1 |
| He, W | 2 |
| Zhang, W | 4 |
| An, Y | 1 |
| Huang, L | 2 |
| Luo, H | 1 |
| Sun, JK | 2 |
| Zhang, Q | 3 |
| Shen, X | 2 |
| Zhou, J | 1 |
| Zhou, SM | 1 |
| Mu, XW | 2 |
| Powell, ES | 1 |
| Bond, WF | 1 |
| Barker, LT | 1 |
| Cooley, K | 1 |
| Lee, J | 3 |
| Vincent, AL | 1 |
| Vozenilek, JA | 1 |
| Erdoğan, M | 2 |
| Findikli, HA | 2 |
| Guarino, M | 1 |
| Perna, B | 1 |
| De Giorgi, A | 1 |
| Gambuti, E | 1 |
| Alfano, F | 1 |
| Catanese, EM | 1 |
| Volpato, S | 1 |
| Strada, A | 1 |
| Caio, G | 1 |
| Contini, C | 1 |
| De Giorgio, R | 1 |
| Wu, Y | 4 |
| Yu, C | 1 |
| Zhou, Y | 4 |
| He, ZM | 1 |
| Fan, J | 1 |
| Sun, Y | 2 |
| Wang, Z | 6 |
| Zhang, L | 4 |
| Xu, F | 1 |
| Han, D | 1 |
| Lyu, J | 1 |
| Yoon, SH | 1 |
| Choi, B | 1 |
| Eun, S | 1 |
| Bae, GE | 1 |
| Koo, CM | 1 |
| Kim, MK | 1 |
| Matoori, S | 1 |
| Mooney, DJ | 1 |
| Lorente, L | 12 |
| Martín, MM | 12 |
| Ortiz-López, R | 5 |
| Pérez-Cejas, A | 7 |
| Ferrer-Moure, C | 2 |
| González, O | 1 |
| Jiménez, A | 12 |
| González-Rivero, AF | 7 |
| Chen, H | 7 |
| Gong, SR | 1 |
| Yu, RG | 1 |
| Simsek, C | 1 |
| Karatas, M | 1 |
| Tatar, E | 1 |
| Yildirim, AM | 1 |
| Tasli Alkan, F | 1 |
| Uslu, A | 1 |
| Julienne, J | 1 |
| Douillet, D | 1 |
| Mozziconacci, MS | 1 |
| Callahan, JC | 1 |
| Gómez-Bernal, F | 3 |
| González-Mesa, A | 2 |
| Daga, MK | 1 |
| Rohatgi, I | 1 |
| Mishra, R | 1 |
| Kumar, N | 1 |
| Mawari, G | 1 |
| Mishra, TK | 1 |
| Singh, S | 2 |
| Shukla, J | 1 |
| Maiwall, R | 1 |
| Pasupuleti, SSR | 1 |
| Hidam, AK | 1 |
| Tevethia, H | 1 |
| Kumar, G | 1 |
| Sahney, A | 1 |
| Mitra, LG | 1 |
| Sarin, SK | 1 |
| Galtung, N | 1 |
| Diehl-Wiesenecker, E | 1 |
| Lehmann, D | 1 |
| Markmann, N | 1 |
| Bergström, WH | 1 |
| Wacker, J | 1 |
| Liesenfeld, O | 2 |
| Mayhew, M | 1 |
| Buturovic, L | 1 |
| Luethy, R | 1 |
| Sweeney, TE | 2 |
| Tauber, R | 1 |
| Kappert, K | 1 |
| Somasundaram, R | 1 |
| Bauer, W | 1 |
| Patel, S | 1 |
| Puri, N | 1 |
| Kiatamornrak, P | 1 |
| Boobphahom, S | 1 |
| Lertussavavivat, T | 1 |
| Rattanawaleedirojn, P | 1 |
| Chailapakul, O | 1 |
| Rodthongkum, N | 1 |
| Srisawat, N | 1 |
| Yang, MX | 1 |
| Wu, ZZ | 1 |
| Liao, XY | 1 |
| Zhang, BL | 1 |
| Chen, X | 4 |
| Lin, JD | 1 |
| Cuenca, JA | 1 |
| Manjappachar, NK | 1 |
| Ramírez, CM | 1 |
| Hernandez, M | 2 |
| Martin, P | 1 |
| Gutierrez, C | 1 |
| Rathi, N | 1 |
| Price, KJ | 1 |
| Nates, JL | 1 |
| Gosselin, M | 1 |
| Mabire, C | 1 |
| Pasquier, M | 1 |
| Carron, PN | 1 |
| Hugli, O | 1 |
| Ageron, FX | 1 |
| Dami, F | 1 |
| Liu, J | 6 |
| Zhou, G | 2 |
| Chen, R | 1 |
| Tong, Z | 2 |
| Rubio-Díaz, R | 2 |
| Julián-Jiménez, A | 2 |
| González Del Castillo, J | 2 |
| García-Lamberechts, EJ | 2 |
| Huarte Sanz, I | 2 |
| Navarro Bustos, C | 2 |
| Candel González, FJ | 1 |
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| Yin, J | 1 |
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| Hwang, SY | 6 |
| Shin, J | 3 |
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| Gao, D | 1 |
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| Wang, Q | 1 |
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| Kostaki, A | 1 |
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| Uhle, F | 2 |
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| Sangari, A | 1 |
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| Conway, JAS | 1 |
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| Wu, W | 2 |
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| De Santos Castro, PÁ | 1 |
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| Wu, C | 2 |
| Ouyang, L | 1 |
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| Zhong, D | 1 |
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| Li, J | 11 |
| Fan, M | 4 |
| Yang, K | 3 |
| Zhang, X | 5 |
| Xu, J | 9 |
| Tu, F | 5 |
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| Gill, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center, Randomized, Controlled, Pivotal Study to Assess the Safety and Efficacy of a Selective Cytopheretic Device in Patients With Acute Kidney Injury Requiring Continuous Kidney Replacement Therapy[NCT05758077] | 200 participants (Anticipated) | Interventional | 2023-04-17 | Recruiting | |||
| Impact of Thiamine Supplementation on Mortality in Septic Shock. A Controlled Before-and-after Study.[NCT05840718] | 80 participants (Anticipated) | Observational | 2023-09-30 | Not yet recruiting | |||
| Risk Factors for Multidrug Resistant Bacteria at ICU Admission[NCT05983861] | 400 participants (Anticipated) | Observational | 2023-09-01 | Not yet recruiting | |||
| Incidence of Hypotension in the Weaning From Vasopressor Drugs[NCT05506319] | 78 participants (Anticipated) | Interventional | 2022-04-04 | Recruiting | |||
| Assessing Baseline Cortisol Levels in Patients Admitted With Septic Shock in Intensive Care Unit; A Single Centre Real World Study.[NCT05741762] | 50 participants (Anticipated) | Observational | 2023-01-31 | Recruiting | |||
| Comparison of Colloid (20% Albumin) Versus Crystalloid (Plasmalyte) for Fluid Resuscitation in Cirrhotics With Sepsis Induced Hypotension.[NCT02721238] | 100 participants (Actual) | Interventional | 2016-12-01 | Completed | |||
| Sepsis Prognosis and Diagnosis in the Emergency Department Using a Host Response Classifier (SPEED) UK - a Multi-Centre Observational Study[NCT05639504] | 0 participants (Actual) | Observational | 2022-12-31 | Withdrawn (stopped due to Study never started, change in company focus on US) | |||
| Pneumonia Direct Pilot[NCT06181669] | 250 participants (Anticipated) | Observational | 2024-01-31 | Not yet recruiting | |||
| Septic Shock Management Guided by Ultrasound: A Randomized Control Trial (SEPTICUS Trial)[NCT04728529] | 340 participants (Anticipated) | Interventional | 2021-09-02 | Recruiting | |||
| Randomized Controlled Trial of Dopamine, Adrenaline, and Blood Transfusion for Treatment of Fluid Refractory Shock in Children With Severe Acute Malnutrition or Severe Underweight and Cholera or Other Dehydrating Diarrheas[NCT04750070] | Phase 3 | 135 participants (Anticipated) | Interventional | 2021-08-17 | Recruiting | ||
| Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis (REVAMP-Sepsis)[NCT05975671] | 52,500 participants (Anticipated) | Interventional | 2023-08-21 | Recruiting | |||
| Physiological Effects of Lactate in Individuals With Chronic Heart Failure[NCT06121323] | 12 participants (Anticipated) | Interventional | 2023-11-22 | Not yet recruiting | |||
| Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance[NCT03249597] | 956 participants (Actual) | Observational | 2017-04-03 | Completed | |||
| Are the Changes in Immature Granulocyte Count and Percentage Significant in the Decision to Continue Medical Treatment of Uncomplicated Acute Appendicitis Cases[NCT04462588] | 64 participants (Actual) | Observational [Patient Registry] | 2019-06-01 | Completed | |||
| Resuscitation Failure, Protein Carbonyl and Receptor Interacting Protein Kinase 3 as Mortality Predictor in Septic Patient[NCT04169412] | 72 participants (Actual) | Observational [Patient Registry] | 2019-02-22 | Completed | |||
| Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965] | 350 participants (Anticipated) | Observational | 2018-08-15 | Active, not recruiting | |||
| Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients: Pathophysiological Determinants, and Relation to Changes in Systemic, Regional and Microcirculatory Blood Flow[NCT04693923] | 42 participants (Anticipated) | Interventional | 2021-02-01 | Not yet recruiting | |||
| Venoarterial PCO2 Difference /Arteriovenous O2 Content Difference Ratio as Goal of Early Severe Sepsis and Septic Shock Therapy[NCT01877798] | 300 participants (Anticipated) | Interventional | 2013-06-30 | Not yet recruiting | |||
| The Thiamine Administration After Cardiac Surgery Trial[NCT04641104] | Phase 4 | 200 participants (Actual) | Interventional | 2020-11-20 | Completed | ||
| Early Recognition and Dynamic Risk Warning System of Multiple Organ Dysfunction Syndrome Caused by Sepsis[NCT04904289] | 60,000 participants (Anticipated) | Observational | 2022-04-21 | Recruiting | |||
| The Early Predictive Roles of NLR and NE% in In-hospital Mortality of Septic Patients: a Single-center 13-year Retrospective Study[NCT05636202] | 606 participants (Actual) | Observational | 2022-12-01 | Completed | |||
| Oxygen for Category II Intrauterine Fetal Resuscitation: A Randomized, Noninferiority Trial[NCT02741284] | 114 participants (Actual) | Interventional | 2016-06-30 | Completed | |||
| Develop, Implement and Assess Effectiveness of Early Warning Score (EWS) for Moneragala District General Hospital[NCT02523456] | 18,000 participants (Actual) | Interventional | 2015-05-01 | Completed | |||
| Randomized Double-blind Placebo-controlled Trial of Inhaled Nitric Oxide for the Treatment of Microcirculatory Dysfunction and Organ Failure in Sepsis[NCT00608322] | Phase 3 | 49 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| Early Goal Directed Therapy Using a Physiological Holistic View. A Multicenter Study in Latin America: The ANDROMEDA-SHOCK Study[NCT03078712] | 424 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Lactate and Sepsis : What Dosage Use as Triage Tool in Emergency Department for Patients With Suspected Infection.[NCT01964690] | 103 participants (Actual) | Observational | 2013-12-31 | Completed | |||
| Medical Education for Sepsis Source Control and Antibiotics[NCT01187134] | 4,138 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| Role of Lactate Level in Prediction of Patients'Acute Gastrointestinal Bleeding Admissions to Intensive Care Unit, Interventions and Short Term Outcomes[NCT04104425] | 300 participants (Actual) | Observational | 2020-01-15 | Completed | |||
| Can Venous Lactate Predict the Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients Without Hemodynamic Shock in Emergency Department?[NCT01947127] | 458 participants (Actual) | Observational [Patient Registry] | 2013-03-31 | Completed | |||
| Hemodynamic Resuscitation and Monitoring in Early Sepsis[NCT04143035] | 500 participants (Anticipated) | Observational | 2019-10-22 | Active, not recruiting | |||
| Comment Diminuer Les hémocultures Inutiles : Construction et Validation d'un Score prédictif de positivité Des hémocultures en réanimation.[NCT05686577] | 2,400 participants (Anticipated) | Observational | 2022-11-22 | Recruiting | |||
| Early Efferon LPS Hemoperfusion Through Hypercrosslinked Styrene-divinylbenzene Copolymer With Immobilized LPS-selective Ligand for Treatment of Patients With Septic Shock[NCT04884854] | 9 participants (Actual) | Observational | 2019-09-13 | Completed | |||
| The Correlation of Regional Cerebral Oxygen Saturation(rScO2) Variation in Passive Leg Raising (PLR) With Neurological Outcomes of Sepsis and Septic Shock Patients[NCT03523169] | 120 participants (Actual) | Observational [Patient Registry] | 2016-12-31 | Completed | |||
| Evaluation of the PliNOSa® Test as an Aid in the Risk Assessment for the Onset of Sepsis[NCT01371929] | 166 participants (Actual) | Observational | 2013-02-04 | Terminated (stopped due to NIH funding ended prior to full enrollment in the clinical study) | |||
| Impact of Intraoperative Goal-directed Blood Pressure Management and Dexmedetomidine on Outcomes of High-risk Patients After Major Abdominal Surgeries: a 2×2 Factorial Randomized Controlled Trial[NCT03933306] | Phase 4 | 496 participants (Actual) | Interventional | 2019-05-20 | Active, not recruiting | ||
| La Sepsi Nel Paziente Anziano: Studio Prospettico Sui Pazienti Ricoverati in Ambiente Internistico.[NCT04945889] | 580 participants (Actual) | Observational | 2019-04-01 | Completed | |||
| DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study)[NCT04624945] | 150 participants (Anticipated) | Observational | 2020-11-25 | Recruiting | |||
| To Compare the Effectiveness of Various Methods of Estimating Volume Resuscitation in Patients With Cirrhosis With Sepsis Induced Hypotension[NCT05059795] | 75 participants (Anticipated) | Observational | 2020-02-01 | Recruiting | |||
| Targeted Tissue Perfusion Versus Macrocirculatory-guided Standard Care in Patients With Septic Shock [TARTARE-2S]- A Multicentre Randomized Controlled Trial[NCT02579525] | 200 participants (Actual) | Interventional | 2016-05-31 | Completed | |||
| An Observational Cohort Study to Validate SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism[NCT05568927] | 150 participants (Anticipated) | Observational | 2022-11-01 | Enrolling by invitation | |||
| [NCT02566460] | 360 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| Determination of Ka of Isolated Plasma and Whole Blood of Critically Ill Patients With Sepsis, Non-septic Patients and Healthy Volunteers: an International, In-vitro Acid-base Study.[NCT03966664] | 90 participants (Anticipated) | Observational | 2019-06-03 | Recruiting | |||
| Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)[NCT02742974] | 196 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
| Contribution of Pre-hospital Blood Lactate Level for Pre-hospital Orientation of Septic Shock[NCT03831685] | 1,000 participants (Anticipated) | Observational | 2018-03-01 | Recruiting | |||
| Lactate Assessment in the Treatment of Early Sepsis: The LactATES Trial[NCT00372502] | 300 participants (Actual) | Interventional | 2007-01-31 | Completed | |||
| Clinical Study of Central Venous-to-Arterial Carbon Dioxide Difference(Pcv-aCO2) in the Evaluation of Fluid Therapy for Postoperative Patients With Abdominal Cancer[NCT02977429] | 150 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)[NCT01128413] | 22 participants (Actual) | Interventional | 2010-07-31 | Terminated (stopped due to lack of resources) | |||
| Assessing Targeted Fluid Resuscitation Strategies Among Patients With Severe Sepsis and Septic Shock[NCT03137446] | 113 participants (Actual) | Interventional | 2017-04-20 | Completed | |||
| Lactate Clearance and Mortality in Patients With Severe Sepsis and Septic Shock: Comparison by Hepatic Dysfunction[NCT01709565] | 245 participants (Anticipated) | Observational | 2012-07-31 | Recruiting | |||
| Heparin Binding Protein (HBP) in Sepsis for the Prediction of Disease Progression[NCT02533011] | 1,055 participants (Actual) | Observational | 2015-07-31 | Completed | |||
| Physician Administered Antibiotics in a Prehospital Mobile Emergency Care Unit[NCT03919851] | 117 participants (Actual) | Observational | 2018-10-31 | Completed | |||
| Evaluation of Hepatic Mitochondrial Function in Sepsis[NCT00889083] | 0 participants (Actual) | Observational | 2009-04-30 | Withdrawn (stopped due to no patients to include) | |||
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| The Prognostic Value of Simultaneous Assessment of Microcirculation Alteration With Sublingual Microcirculation and Near-infrared Spectroscopy on the Acute Respiratory Distress Syndrome of Various Phenotypes[NCT05180409] | 60 participants (Anticipated) | Observational | 2020-12-01 | Recruiting | |||
| Near-infrared Spectroscopic Measurement of Tissue Oxygen Saturation and the Vascular Occlusion Test in Complex Regional Pain Syndrome[NCT01586377] | 20 participants (Actual) | Observational | 2011-08-31 | Completed | |||
| Personalised Medicine With IgGAM Compared With Standard of Care for Treatment of Peritonitis After Infectious Source Control (the PEPPER Trial): a Randomised, Controlled Trial[NCT03334006] | Phase 2 | 200 participants (Anticipated) | Interventional | 2017-11-20 | Suspended (stopped due to Due to safety-relevant aspects with regard to internal processes of the sponsor) | ||
| The Effect of Pre- and Postoperative Supplemental Enteral Nutrition in High-Risk Patients Undergoing Elective Cardiac Surgery. A Prospective Double Blind Study.[NCT00247793] | 0 participants | Interventional | 1996-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Determined by umbilical artery cord gas collected at time of delivery and only in patients with paired (umbilical artery and umbilical vein) cord gases. (NCT02741284)
Timeframe: At delivery
| Intervention | mmol/L (Mean) |
|---|---|
| Room Air | 3.5 |
| Oxygen | 3.4 |
Number of patients with resolution of recurrent variable or recurrent late decelerations within 60 minutes of randomization (NCT02741284)
Timeframe: 60 minutes after randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| No Oxygen | 49 |
| Oxygen | 43 |
As determined by cord gas collection at time of delivery (NCT02741284)
Timeframe: At time of delivery
| Intervention | meq/L (Mean) |
|---|---|
| Room Air | -3.6 |
| Oxygen | -3.6 |
Partial pressure of carbon dioxide as collected on cord gases at time of delivery (NCT02741284)
Timeframe: At time of delivery
| Intervention | mmHg (Mean) |
|---|---|
| Room Air | 55.9 |
| Oxygen | 57.4 |
Determined by umbilical artery cord gas collected at time of delivery and only in patients with paired (umbilical artery and umbilical vein) cord gases. (NCT02741284)
Timeframe: At time of delivery
| Intervention | pH units (Mean) |
|---|---|
| Room Air | 7.26 |
| Oxygen | 7.25 |
Partial pressure of oxygen as collected on cord gases at time of delivery (NCT02741284)
Timeframe: Time of delivery
| Intervention | mm Hg (Mean) |
|---|---|
| Room Air | 19.7 |
| Oxygen | 24.4 |
Delivery via Cesarean section, operative vaginal delivery (forceps or vacuum), or spontaneous vaginal delivery (NCT02741284)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Cesarean delivery | Cesarean delivery for non reassuring fetal status | Operative vaginal delivery | Spontaenous vaginal delivery | |
| Oxygen | 6 | 2 | 1 | 41 |
| Room Air | 2 | 0 | 6 | 43 |
The MFI is a continuous scale from 0-3, with 3.0 being better outcome and 0.0 being worse outcome. (NCT00608322)
Timeframe: 0-2 hours of study drug administration
| Intervention | units on a scale (Median) |
|---|---|
| Inhaled Nitric Oxide | -0.06 |
| Sham (Comparator) | -0.03 |
Electronic database retrieval of in- and outpatient clinical records together with telephone follow-ups to the patients or their contact personnel are employed to every case in the next 30 days after the day of presentation to the emergency department to identify the deceased cases. All-cause mortality rates of each cohort will be compared by the survival analysis. (NCT01947127)
Timeframe: 30 days after the day of presentation to the emergency department
| Intervention | participants (Number) |
|---|---|
| High Lactate | 18 |
| Low Lactate | 13 |
Numbers of days spent in the hospital since the emergency department arrival to hospital discharge (NCT01947127)
Timeframe: Patients will be followed for the duration of hospital stay, an expected average of 7 days
| Intervention | Days (Median) |
|---|---|
| High Lactate | 6 |
| Low Lactate | 3 |
Proportion of the patients in each cohort who require vasopressor/mechanical ventilator to maintain their vital signs in the next 72 hours after venous lactate measurement. (NCT01947127)
Timeframe: 72 hours after venous lactate measurement
| Intervention | participants (Number) |
|---|---|
| High Lactate | 53 |
| Low Lactate | 21 |
The median lactate clearance from time zero to within 6 hours of the ED stay. (NCT01128413)
Timeframe: The median lactate clearance within 6 hours of the ED stay.
| Intervention | percent lactate clearance (Median) |
|---|---|
| Fluid Optimization (FO) | 54 |
| Routine Care (RC) | 56 |
61 reviews available for lactic acid and Blood Poisoning
| Article | Year |
|---|---|
What Is the Utility of Measuring Lactate Levels in Patients with Sepsis and Septic Shock?
Topics: Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis; Shock, Septic | 2021 |
Levosimendan versus dobutamine for sepsis-induced cardiac dysfunction: a systematic review and meta-analysis.
Topics: Disease-Free Survival; Dobutamine; Heart Diseases; Lactic Acid; Sepsis; Simendan; Stroke Volume; Sur | 2021 |
Recent Advances in Bedside Device-Based Early Detection of Sepsis.
Topics: Biomarkers; Emergency Service, Hospital; Humans; Lactic Acid; Sepsis; Systemic Inflammatory Response | 2022 |
Using the lactate-to-albumin ratio to predict mortality in patients with sepsis or septic shock: a systematic review and meta-analysis.
Topics: Albumins; Humans; Lactic Acid; ROC Curve; Sepsis; Shock, Septic | 2022 |
Sepsis Management for the Nephrologist.
Topics: Fluid Therapy; Humans; Lactic Acid; Nephrologists; Sepsis; Shock, Septic; Vasoconstrictor Agents | 2022 |
The evolving value of older biomarkers in the clinical diagnosis of pediatric sepsis.
Topics: Adult; Biomarkers; C-Reactive Protein; Child; Humans; Lactic Acid; Procalcitonin; Reproducibility of | 2023 |
Predictors of survival for pediatric extracorporeal cardiopulmonary resuscitation: A systematic review and meta-analysis.
Topics: Cardiopulmonary Resuscitation; Child; Creatinine; Humans; Lactic Acid; Nervous System Diseases; Oxyg | 2022 |
Does lactate enhance the prognostic accuracy of the quick Sequential Organ Failure Assessment for adult patients with sepsis? A systematic review.
Topics: Adult; Hospital Mortality; Humans; Lactic Acid; Organ Dysfunction Scores; Prognosis; Prospective Stu | 2022 |
Impact of supplemental thiamin on lactate levels in adults with septic shock.
Topics: Ascorbic Acid; Humans; Hydrocortisone; Lactic Acid; Observational Studies as Topic; Retrospective St | 2023 |
Sepsis triggers and tools to support early identification in healthcare settings: An integrative review.
Topics: Adult; Child; Delivery of Health Care; Emergency Service, Hospital; Hospital Mortality; Humans; Infa | 2023 |
Potential biomarker for diagnosis and therapy of sepsis: Lactylation.
Topics: Biomarkers; Epigenesis, Genetic; Humans; Lactic Acid; Sepsis | 2023 |
Demystifying Lactate in the Emergency Department.
Topics: Acidosis, Lactic; Emergency Service, Hospital; Humans; Hyperlactatemia; Lactic Acid; Prognosis; Seps | 2020 |
The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU.
Topics: Anaerobiosis; Blood Glucose; Critical Care; Cytosol; Endurance Training; Fatty Acids; Glycolysis; Hu | 2020 |
[Lactate in emergency medicine].
Topics: Emergency Medicine; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Shock | 2020 |
Macrocirculatory and Microcirculatory Endpoints in Sepsis Resuscitation.
Topics: Hemodynamics; Humans; Lactic Acid; Microcirculation; Resuscitation; Sepsis; Shock, Septic | 2021 |
Blood lactate levels in sepsis: in 8 questions.
Topics: Critical Illness; Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis | 2021 |
The role of lactate in sepsis and COVID-19: Perspective from contracting skeletal muscle metabolism.
Topics: Adrenergic Agents; COVID-19; Humans; Hypoxia; Lactate Dehydrogenases; Lactic Acid; Muscle, Skeletal; | 2022 |
Predicting mortality in adult patients with sepsis in the emergency department by using combinations of biomarkers and clinical scoring systems: a systematic review.
Topics: Adult; Biomarkers; Emergency Service, Hospital; Hospital Mortality; Humans; Interleukin-6; Lactic Ac | 2021 |
Big Tests in Little People.
Topics: Asthma; Biomarkers; Child; Fibrin Fibrinogen Degradation Products; Heart Diseases; Humans; Infection | 2021 |
Lactate and Immunosuppression in Sepsis.
Topics: Animals; Glycolysis; Humans; Immunity, Innate; Immunosuppression Therapy; Lactic Acid; Sepsis | 2018 |
Sepsis and Septic Shock Strategies.
Topics: Anti-Bacterial Agents; Arterial Pressure; Cardiomyopathies; Central Venous Pressure; Critical Care; | 2017 |
Point-of-care lactate testing for sepsis at presentation to health care: a systematic review of patient outcomes.
Topics: Anti-Bacterial Agents; Biomarkers; Emergency Service, Hospital; Humans; Lactic Acid; Patient Outcome | 2017 |
Review article: Sepsis in the emergency department - Part 2: Investigations and monitoring.
Topics: Adrenomedullin; Anti-Bacterial Agents; Bacterial Infections; Biomarkers; C-Reactive Protein; Calcito | 2018 |
Sepsis: Updated definitions and optimized management.
Topics: Anti-Bacterial Agents; Diagnosis, Differential; Early Diagnosis; Early Medical Intervention; Humans; | 2016 |
[Lactic acidosis - update 2018].
Topics: Acidosis, Lactic; Critical Care; Humans; Lactic Acid; Liver Diseases; Metabolic Clearance Rate; Prog | 2018 |
Agreement between arterial and peripheral venous lactate levels in the ED: A systematic review.
Topics: Arteries; Emergency Service, Hospital; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Veins | 2019 |
Relative efficacy and safety of early lactate clearance-guided therapy resuscitation in patients with sepsis: A meta-analysis.
Topics: Biomarkers; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Length of Stay; Organ Dys | 2019 |
Qinwen Baidu decoction for sepsis: A protocol for a systematic review and meta-analysis.
Topics: APACHE; Arterial Pressure; C-Reactive Protein; Drugs, Chinese Herbal; Humans; Intensive Care Units; | 2019 |
Sepsis: evolving concepts and challenges.
Topics: Humans; Lactic Acid; Medical Illustration; Organ Dysfunction Scores; Sepsis | 2019 |
Beyond Mean Arterial Pressure and Lactate: Perfusion End Points for Managing the Shocked Patient.
Topics: Acute Kidney Injury; Arterial Pressure; Biomarkers; Blood Circulation; Carbon Dioxide; Cardiac Outpu | 2019 |
[Initial resuscitation bundle and monitoring tissue perfusion in severe sepsis].
Topics: Anti-Bacterial Agents; Chile; Humans; Hypotension; Intensive Care Units; Lactic Acid; Regional Blood | 2013 |
Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio.
Topics: Adult; Aged; Female; Humans; Interleukin-10; International Normalized Ratio; Lactic Acid; Logistic M | 2014 |
The role of immune and metabolic biomarkers for improved management of sepsis patients.
Topics: Adrenomedullin; Algorithms; Animals; Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; Early | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Fluid Therapy; Humans; Lactic Acid; Randomized Controlled Trials as Topic; Sepsis | 2015 |
Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Fluid Therapy; Humans; Lactic Acid; Randomized Controlled Trials as Topic; Sepsis | 2015 |
Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Fluid Therapy; Humans; Lactic Acid; Randomized Controlled Trials as Topic; Sepsis | 2015 |
Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Fluid Therapy; Humans; Lactic Acid; Randomized Controlled Trials as Topic; Sepsis | 2015 |
Oxygen extraction and perfusion markers in severe sepsis and septic shock: diagnostic, therapeutic and outcome implications.
Topics: Biomarkers; Blood Gas Analysis; Critical Care; Humans; Lactic Acid; Oxygen; Oxygen Consumption; Perf | 2015 |
The value of blood lactate kinetics in critically ill patients: a systematic review.
Topics: Critical Illness; Humans; Intensive Care Units; Lactic Acid; Sepsis | 2016 |
Evolution of Sepsis Management: From Early Goal-Directed Therapy to Personalized Care.
Topics: Anti-Bacterial Agents; Fluid Therapy; Goals; Humans; Lactic Acid; Precision Medicine; Resuscitation; | 2016 |
The role of central venous oxygen saturation, blood lactate, and central venous-to-arterial carbon dioxide partial pressure difference as a goal and prognosis of sepsis treatment.
Topics: Carbon Dioxide; Humans; Lactic Acid; Oxygen; Partial Pressure; Patient Care Planning; Prognosis; Pro | 2016 |
[Updated definition of sepsis : Implications for diagnostics and therapy principles].
Topics: Diagnosis, Differential; Fluid Therapy; Guideline Adherence; Humans; Hypotension; Lactic Acid; Sepsi | 2017 |
The new sepsis definition: limitations and contribution to research and diagnosis of sepsis.
Topics: Consensus Development Conferences as Topic; Humans; Lactic Acid; Organ Dysfunction Scores; Sepsis; S | 2017 |
Management of sepsis: early resuscitation.
Topics: Calcitonin; Critical Care; Hemodynamics; Humans; Lactic Acid; Multiple Organ Failure; Natriuretic Pe | 2008 |
Management of sepsis in the ICU.
Topics: Adrenal Cortex Hormones; Anti-Infective Agents; Critical Care; Humans; Hyperglycemia; Hypoglycemic A | 2009 |
Risk stratification of the potentially septic patient in the emergency department: the Mortality in the Emergency Department Sepsis (MEDS) score.
Topics: Aged; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Emergency Service, Hospital; | 2009 |
Blood lactate monitoring in critically ill patients: a systematic health technology assessment.
Topics: Acidosis, Lactic; Algorithms; Critical Care; Decision Support Techniques; Humans; Lactic Acid; Monit | 2009 |
Sepsis-induced tissue hypoperfusion.
Topics: Hemodynamics; Humans; Lactic Acid; Microcirculation; Oxygen; Resuscitation; Sepsis; Shock, Septic; S | 2009 |
[Volume replacement in intensive care medicine].
Topics: Blood Pressure; Blood Volume; Cardiomyopathy, Dilated; Cholecystectomy; Colloids; Critical Care; Goa | 2011 |
Early interventions in severe sepsis and septic shock: a review of the evidence one decade later.
Topics: Algorithms; Early Medical Intervention; Humans; Lactic Acid; Resuscitation; Sepsis; Shock, Septic; T | 2012 |
Organisation and planning of anaesthesia for emergency surgery.
Topics: Anesthesia; Case Management; Death; Emergency Medical Services; General Surgery; Humans; Lactic Acid | 2013 |
Bench-to-bedside review: lactate and the lung.
Topics: Glucose; Humans; Lactic Acid; Lung; Respiratory Distress Syndrome; Sepsis | 2002 |
[Bacterial meningitis as a complication of Fusobacterium necroforum infection in adults].
Topics: Adult; Anti-Bacterial Agents; Blood Glucose; Cerebrospinal Fluid Proteins; Diagnosis, Differential; | 2003 |
Splanchnic metabolism in acute liver failure and sepsis.
Topics: Humans; Ketone Bodies; Lactic Acid; Liver Failure, Acute; Oxygen Consumption; Sepsis; Splanchnic Cir | 2004 |
The role of bundles in sepsis care.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Blood Glucose; Clinical Protocols; Critical Care; Dose | 2006 |
Mitochondrial function in sepsis: respiratory versus leg muscle.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Humans; Lactic Acid; Leg; Locomotion; Mitochondr | 2007 |
Substrate utilization in sepsis and multiple organ failure.
Topics: Critical Illness; Energy Metabolism; Fatty Acids, Omega-3; Fish Oils; Humans; Inflammation Mediators | 2007 |
[Is infection and septic shock caused by a global oxygen deficiency? An overview in 2 parts. 1: Infection and correlation between DO2 and VO2].
Topics: Acid-Base Equilibrium; Cardiac Output; Humans; Hypoxia; Lactates; Lactic Acid; Oxygen; Oxygen Consum | 1996 |
Interpretation of lactate levels in critical illness.
Topics: Critical Illness; Humans; Lactic Acid; Prognosis; Pyruvate Dehydrogenase Complex; Sepsis | 1998 |
Lactate in sepsis and trauma--hindrance or help?
Topics: Acidosis, Lactic; Biomarkers; Humans; Lactic Acid; Sepsis; Wounds and Injuries | 1999 |
Dysoxia and lactate.
Topics: Acidosis, Lactic; Adult; Cell Hypoxia; Child; Critical Illness; Forecasting; Humans; Lactic Acid; Ox | 1999 |
Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis.
Topics: Acidosis, Lactic; Animals; Blood Gas Analysis; Cell Hypoxia; Energy Metabolism; Fluorine Radioisotop | 1992 |
Experimental models of pathologic oxygen supply dependency.
Topics: Animals; Endotoxins; Humans; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Respiratory Distress | 1991 |
23 trials available for lactic acid and Blood Poisoning
| Article | Year |
|---|---|
A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial].
Topics: Albumins; Critical Illness; Electrolytes; Fluid Therapy; Humans; Hypotension, Controlled; Lactic Aci | 2022 |
Neutralization of extracellular histones by sodium-Β-O-methyl cellobioside sulfate in septic shock.
Topics: Animals; Female; Hemodynamics; Histones; Interleukin-6; Lactic Acid; Norepinephrine; Sepsis; Sheep; | 2023 |
Effect of magnesium supplementation on lactate clearance in critically ill patients with severe sepsis: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Critical Illness; Female; Humans; Intensive Care Units; Lactic A | 2020 |
Early Lactate-Guided Resuscitation of Elderly Septic Patients.
Topics: Aged; Fluid Therapy; Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis; Shock, Septic | 2022 |
The use of mid-regional proadrenomedullin to identify disease severity and treatment response to sepsis - a secondary analysis of a large randomised controlled trial.
Topics: Adrenomedullin; Aged; Aged, 80 and over; APACHE; Biomarkers; C-Reactive Protein; Calcitonin; Female; | 2018 |
P(v-a)CO2/C(a-v)O2-directed resuscitation does not improve prognosis compared with SvO2 in severe sepsis and septic shock: A prospective multicenter randomized controlled clinical study.
Topics: Arterial Pressure; Blood Gas Analysis; Carbon Dioxide; China; Female; Humans; Lactic Acid; Male; Mid | 2018 |
Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis*.
Topics: Academic Medical Centers; Administration, Inhalation; Adult; Aged; Double-Blind Method; Female; Hosp | 2014 |
Effectiveness of arterial, venous, and capillary blood lactate as a sepsis triage tool in ED patients.
Topics: Aged; Arteries; Blood Specimen Collection; Capillaries; Emergency Service, Hospital; Female; Humans; | 2015 |
Lactate Clearance and Vasopressor Seem to Be Predictors for Mortality in Severe Sepsis Patients with Lactic Acidosis Supplementing Sodium Bicarbonate: A Retrospective Analysis.
Topics: Acidosis, Lactic; Aged; C-Reactive Protein; Female; Hospital Mortality; Humans; Lactic Acid; Male; M | 2015 |
Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Patients with Sepsis.
Topics: Adult; Aged; Cardiac Output; Emergency Service, Hospital; Female; Fluid Therapy; Humans; Lactic Acid | 2016 |
Use of stepwise lactate kinetics-oriented hemodynamic therapy could improve the clinical outcomes of patients with sepsis-associated hyperlactatemia.
Topics: Adult; Aged; Chi-Square Distribution; China; Female; Guidelines as Topic; Heart Rate; Hemodynamics; | 2017 |
[The study of the mechanism of the effect of heparin on tissue perfusion of sepsis patients].
Topics: Adolescent; Adult; Aged; Anticoagulants; Female; Fibrin Fibrinogen Degradation Products; Heparin; Hu | 2008 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
Topics: Adult; Aged; Cardiotonic Agents; Central Venous Pressure; Dobutamine; Erythrocyte Transfusion; Femal | 2010 |
[Short term effects of hypertonic saline during severe sepsis and septic shock].
Topics: Adult; Aged; Aged, 80 and over; Blood Proteins; Catheterization, Swan-Ganz; Critical Care; Female; H | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Topics: Biomarkers; Cohort Studies; Emergency Medical Services; Female; Hospital Mortality; Humans; Lactic A | 2004 |
[Effects of raw rhubarb on plasma D-lactate and procalcitonin expressions in patients with sepsis].
Topics: Aged; Calcitonin; Calcitonin Gene-Related Peptide; Drugs, Chinese Herbal; Female; Humans; Lactic Aci | 2006 |
[The design of the VISEP trial. Critical appraisal].
Topics: Acute Kidney Injury; Blood Glucose; Colloids; Critical Care; Crystalloid Solutions; Endpoint Determi | 2007 |
Point-of-care lactate testing predicts mortality of severe sepsis in a predominantly HIV type 1-infected patient population in Uganda.
Topics: Adult; Female; HIV Infections; HIV-1; Humans; Lactic Acid; Male; Point-of-Care Systems; Predictive V | 2008 |
Prognostic value of the dobutamine test in patients with sepsis syndrome and normal lactate values: a prospective, multicenter study.
Topics: Adult; Aged; Critical Illness; Dobutamine; Female; Hemodynamics; Humans; Infusions, Intravenous; Lac | 1993 |
Effects of blood transfusion on oxygen transport variables in severe sepsis.
Topics: Blood Gas Analysis; Blood Transfusion; Combined Modality Therapy; Dobutamine; Hematocrit; Hemodynami | 1993 |
Gastric intramucosal pH and blood lactate in severe sepsis.
Topics: Adult; Aged; Biomarkers; Gastric Acidity Determination; Gastric Mucosa; Humans; Hydrogen-Ion Concent | 1997 |
Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Cytokines; Double-Blind Method; Europe; Female; Hemodynamics | 2000 |
Enteral feeding in sepsis: a prospective, randomized, double-blind trial.
Topics: Adolescent; Adult; Aged; Amino Acids, Branched-Chain; Clinical Trials as Topic; Double-Blind Method; | 1985 |
522 other studies available for lactic acid and Blood Poisoning
| Article | Year |
|---|---|
Sepsis in severe COVID-19 is rarely septic shock: a retrospective single-centre cohort study.
Topics: Aged; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Critical Care; Female; Humans; Lactic Acid; | 2021 |
Prognostic factors for late death in septic shock survivors: a multi-center, prospective, registry-based observational study.
Topics: Adult; Humans; Lactic Acid; Prognosis; Prospective Studies; Registries; Sepsis; Shock, Septic; Survi | 2022 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Blood Glucose; Cardiotonic Agents; Critical Ca | 2021 |
Understanding critically ill sepsis patients with normal serum lactate levels: results from U.S. and European ICU cohorts.
Topics: Aged; Critical Illness; Europe; Female; Hospital Mortality; Humans; Hyperlactatemia; Intensive Care | 2021 |
Serum NLRP3: A biomarker for identifying high-risk septic patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Inflammasomes; Lactic Acid; Male; Middle | 2022 |
Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.
Topics: Anti-Infective Agents; Arterial Pressure; Biomarkers; Critical Care; Diagnosis, Differential; Drug A | 2021 |
The predictive value of cystatin C combined with lactic acid and uric acid in the occurrence of acute kidney injury in sepsis.
Topics: Acute Kidney Injury; Biomarkers; Creatinine; Cystatin C; Humans; Lactic Acid; Predictive Value of Te | 2022 |
Lactate dehydrogenase to albumin ratio as a prognostic factor for patients with severe infection requiring intensive care.
Topics: Aged; Aged, 80 and over; Albumins; APACHE; Blood Urea Nitrogen; C-Reactive Protein; Communicable Dis | 2021 |
The impact of lactate clearance on outcomes according to infection sites in patients with sepsis: a retrospective observational study.
Topics: Aged; Aged, 80 and over; Biomarkers; Critical Care; Emergency Service, Hospital; Female; Hospital Mo | 2021 |
Clinical characteristics and prognosis in patients with urosepsis from intensive care unit in Shanghai, China: a retrospective bi-centre study.
Topics: Age Distribution; Aged; China; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; | 2021 |
Changes in carbon dioxide production and oxygen uptake evaluated using indirect calorimetry in mechanically ventilated patients with sepsis.
Topics: Adult; Calorimetry, Indirect; Carbon Dioxide; Humans; Intensive Care Units; Lactic Acid; Oxygen; Oxy | 2021 |
Utility of specific laboratory biomarkers to predict severe sepsis in pediatric patients with SIRS.
Topics: Adolescent; Area Under Curve; Biomarkers; Blood Sedimentation; C-Reactive Protein; Child; Child, Pre | 2021 |
In-vivo quantification of lactate using Near Infrared reflectance spectroscopy.
Topics: Humans; Lactic Acid; Sepsis; Spectroscopy, Near-Infrared | 2021 |
Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biomarkers; Centers for Medicare | 2021 |
Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool.
Topics: Adult; Anti-Bacterial Agents; Electronic Health Records; Emergency Service, Hospital; Guideline Adhe | 2022 |
Impact of Pulmonary Arterial Hypertension on Systemic Inflammation, Cardiac Injury and Hemodynamics in Sepsis: A Retrospective Study From MIMIC-III.
Topics: C-Reactive Protein; Heart Injuries; Hemodynamics; Humans; Lactic Acid; Pulmonary Arterial Hypertensi | 2022 |
Integrin αEβ7 is involved in the intestinal barrier injury of sepsis.
Topics: Animals; Cadherins; Humans; Integrins; Interleukin-9; Intestinal Diseases; Lactic Acid; Rats; Sepsis | 2022 |
In Situ Simulation for Adoption of New Technology to Improve Sepsis Care in Rural Emergency Departments.
Topics: Emergency Service, Hospital; Guideline Adherence; Hospital Mortality; Humans; Lactic Acid; Sepsis; S | 2022 |
Prognostic value of the lactate/albumin ratio for predicting mortality in patients with pneumosepsis in intensive care units.
Topics: Adult; Critical Illness; Female; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Orga | 2022 |
A 2-year retrospective analysis of the prognostic value of MqSOFA compared to lactate, NEWS and qSOFA in patients with sepsis.
Topics: Emergency Service, Hospital; Hospital Mortality; Humans; Lactic Acid; Organ Dysfunction Scores; Prog | 2022 |
Risk stratification and prognostic value of serum neutrophil gelatinase-associated lipocalin (sNGAL) in sepsis patients.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Lipocalin-2; | 2022 |
The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk factor of 28-day mortality in intensive care units.
Topics: Acute Kidney Injury; Continuous Renal Replacement Therapy; Female; Humans; Intensive Care Units; Lac | 2022 |
Development of a liposomal near-infrared fluorescence lactate assay for human blood.
Topics: Animals; Cattle; Fluorescence; Humans; Kinetics; Lactic Acid; Liposomes; Sepsis | 2022 |
Blood Bcl-2 levels to predict the mortality of septic patients.
Topics: Humans; Lactic Acid; Prognosis; Sepsis; Tumor Necrosis Factor-alpha | 2022 |
Increased normalized lactate load is associated with higher mortality in both sepsis and non-sepsis patients: an analysis of the MIMIC-IV database.
Topics: Humans; Intensive Care Units; Lactic Acid; Prognosis; Retrospective Studies; ROC Curve; Sepsis | 2022 |
Kidney Transplantation From Infected Donors With Particular Emphasis on Multidrug-Resistant Organisms: A Single-Center Cohort Study.
Topics: Cohort Studies; Drug Resistance, Multiple, Bacterial; Humans; Kidney Transplantation; Lactic Acid; R | 2022 |
Prognostic accuracy of using lactate in addition to the quick Sequential Organ Failure Assessment score and the National Early Warning Score for emergency department patients with suspected infection.
Topics: Adult; Early Warning Score; Emergency Service, Hospital; Hospital Mortality; Humans; Lactic Acid; Or | 2023 |
High mortality rate of septic patients with high blood granzyme B concentrations.
Topics: Granzymes; Humans; Intensive Care Units; Lactic Acid; Prognosis; Prospective Studies; Sepsis; Shock, | 2022 |
Lactate enhanced-quick Sequential Organ Failure Assessment 2 (LqSOFA2): A new score for bedside prognostication of patients with sepsis.
Topics: Humans; Intensive Care Units; Lactic Acid; Organ Dysfunction Scores; Prognosis; Prospective Studies; | 2021 |
Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department.
Topics: Biomarkers; Emergency Service, Hospital; Hospital Mortality; Humans; Infections; Lactic Acid; Multip | 2022 |
A portable blood lactate sensor with a non-immobilized enzyme for early sepsis diagnosis.
Topics: Biosensing Techniques; Electrochemical Techniques; Electrodes; Humans; Lactic Acid; Sepsis | 2022 |
Remifentanil reduces multiple organ and energy metabolism disturbances in a rat sepsis model.
Topics: Animals; Energy Metabolism; Epinephrine; Interleukin-6; Lactic Acid; Lipopolysaccharides; Male; Pyru | 2022 |
Outcomes and Predictors of 28-Day Mortality in Patients With Solid Tumors and Septic Shock Defined by Third International Consensus Definitions for Sepsis and Septic Shock Criteria.
Topics: Adult; Consensus; Female; Humans; Intensive Care Units; Lactic Acid; Male; Middle Aged; Neoplasms; P | 2022 |
Prevalence and clinical significance of point of care elevated lactate at emergency admission in older patients: a prospective study.
Topics: Aged; Emergency Service, Hospital; Hospital Mortality; Humans; Lactic Acid; Point-of-Care Systems; P | 2022 |
Mitochondrial Sirt3 serves as a biomarker for sepsis diagnosis and mortality prediction.
Topics: Biomarkers; Humans; Intensive Care Units; Lactic Acid; Prognosis; Retrospective Studies; ROC Curve; | 2022 |
Ability of lactate, procalcitonin, and criteria defining sepsis to predict 30-day mortality, bacteremia, and microbiologically confirmed infection in patients with infection suspicion treated in emergency departments.
Topics: Adolescent; Area Under Curve; Bacteremia; Emergency Service, Hospital; Female; Humans; Lactic Acid; | 2022 |
WIN55212-2 alleviates acute lung injury by inhibiting macrophage glycolysis through the miR-29b-3p/FOXO3/PFKFB3 axis.
Topics: Acute Lung Injury; Animals; Benzoxazines; Glycolysis; Lactic Acid; Lipopolysaccharides; Macrophages; | 2022 |
Association between blood caspase-9 concentrations and septic patient prognosis.
Topics: Caspase 9; Humans; Intensive Care Units; Lactic Acid; Prognosis; Prospective Studies; Retrospective | 2023 |
The Diagnostic Value of Mitochondrial Mass of Peripheral T Lymphocytes in Early Sepsis.
Topics: Biomarkers; Humans; Lactic Acid; Lymphocytes; Mitochondria; Procalcitonin; Prognosis; Retrospective | 2022 |
Early Diagnosis and Prediction of Death Risk in Patients with Sepsis by Combined Detection of Serum PCT, BNP, Lactic Acid, and Apache II Score.
Topics: Early Diagnosis; Humans; Lactic Acid; Natriuretic Peptide, Brain; Procalcitonin; Prognosis; Retrospe | 2022 |
Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors.
Topics: Humans; Hyperlactatemia; Lactic Acid; Prognosis; Retrospective Studies; Sepsis; Shock, Hemorrhagic | 2022 |
A combined qSOFA-lactate model for sepsis-related mortality prediction: a small step towards an elusive answer?
Topics: Hospital Mortality; Humans; Lactic Acid; Organ Dysfunction Scores; Retrospective Studies; Sepsis | 2022 |
Enhanced bedside mortality prediction combining point-of-care lactate and the quick Sequential Organ Failure Assessment (qSOFA) score in patients hospitalised with suspected infection in southeast Asia: a cohort study.
Topics: Adult; Cohort Studies; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Organ Dysfunct | 2022 |
Modified cardiovascular SOFA score in sepsis: development and internal and external validation.
Topics: Humans; Lactic Acid; Organ Dysfunction Scores; Prognosis; Retrospective Studies; ROC Curve; Sepsis; | 2022 |
Prognostic Value of Albumin-to-Fibrinogen Ratio for 28-Day Mortality among Patients with Sepsis from Various Infection Sites.
Topics: Albumins; Communicable Diseases; Fibrinogen; Humans; Lactic Acid; Prognosis; Retrospective Studies; | 2022 |
Septic Shock: Phenotypes and Outcomes.
Topics: Carbon Dioxide; Humans; Intensive Care Units; Lactic Acid; Norepinephrine; Phenotype; Prognosis; Ret | 2022 |
Risk factors for the prognosis of patients with sepsis in intensive care units.
Topics: Case-Control Studies; Humans; Intensive Care Units; Lactic Acid; Prognosis; Retrospective Studies; R | 2022 |
Risk stratification of patients with acute respiratory distress syndrome complicated with sepsis using lactate trajectories.
Topics: APACHE; Humans; Lactic Acid; Respiratory Distress Syndrome; Risk Assessment; Sepsis | 2022 |
A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS.
Topics: Adult; Emergency Service, Hospital; Hospital Mortality; Humans; Infections; Intensive Care Units; La | 2022 |
Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis.
Topics: 5-Hydroxytryptophan; Humans; Intensive Care Units; Lactic Acid; Prognosis; ROC Curve; Sepsis; Seroto | 2022 |
On the ability of lactate, procalcitonin, and criteria defining sepsis to predict 30-day mortality, bacteremia, and microbiologically confirmed infection in patients with suspected infection treated in emergency departments.
Topics: Bacteremia; Emergency Service, Hospital; Humans; Lactic Acid; Procalcitonin; Sepsis | 2022 |
The value of NSE to predict ICU mortality in patients with septic shock: A prospective observational study.
Topics: Bilirubin; Humans; Intensive Care Units; Interleukin-6; Lactic Acid; Phosphopyruvate Hydratase; Prog | 2022 |
Application of oXiris-continuous hemofiltration adsorption in patients with sepsis and septic shock: A single-centre experience in China.
Topics: Adsorption; Biomarkers; China; Hemofiltration; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Re | 2022 |
LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS.
Topics: Animals; Cadherins; Capillary Permeability; Claudin-5; Endothelial Cells; Heat-Shock Proteins; HSP70 | 2022 |
Association between septic patient mortality and blood survivin concentrations.
Topics: Anti-Infective Agents; Humans; Lactic Acid; Prognosis; Prospective Studies; Sepsis; Shock, Septic | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study.
Topics: Biomarkers; Humans; Interleukin-6; Lactic Acid; Procalcitonin; Prognosis; Retrospective Studies; ROC | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
Methylene Blue to Neonatal Septic Shock treatment in neonate pigs
Topics: Animals; Disease Models, Animal; Lactic Acid; Male; Methylene Blue; Neonatal Sepsis; Sepsis; Shock, | 2022 |
Methylene Blue to Neonatal Septic Shock treatment in neonate pigs
Topics: Animals; Disease Models, Animal; Lactic Acid; Male; Methylene Blue; Neonatal Sepsis; Sepsis; Shock, | 2022 |
Methylene Blue to Neonatal Septic Shock treatment in neonate pigs
Topics: Animals; Disease Models, Animal; Lactic Acid; Male; Methylene Blue; Neonatal Sepsis; Sepsis; Shock, | 2022 |
Methylene Blue to Neonatal Septic Shock treatment in neonate pigs
Topics: Animals; Disease Models, Animal; Lactic Acid; Male; Methylene Blue; Neonatal Sepsis; Sepsis; Shock, | 2022 |
Heparin-binding protein as a biomarker of severe sepsis in the pediatric intensive care unit: A multicenter, prospective study.
Topics: Biomarkers; C-Reactive Protein; Child; Humans; Intensive Care Units, Pediatric; Lactic Acid; Procalc | 2023 |
Heparin-binding protein as a biomarker of severe sepsis in the pediatric intensive care unit: A multicenter, prospective study.
Topics: Biomarkers; C-Reactive Protein; Child; Humans; Intensive Care Units, Pediatric; Lactic Acid; Procalc | 2023 |
Heparin-binding protein as a biomarker of severe sepsis in the pediatric intensive care unit: A multicenter, prospective study.
Topics: Biomarkers; C-Reactive Protein; Child; Humans; Intensive Care Units, Pediatric; Lactic Acid; Procalc | 2023 |
Heparin-binding protein as a biomarker of severe sepsis in the pediatric intensive care unit: A multicenter, prospective study.
Topics: Biomarkers; C-Reactive Protein; Child; Humans; Intensive Care Units, Pediatric; Lactic Acid; Procalc | 2023 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Machine learning models to predict in-hospital mortality in septic patients with diabetes.
Topics: Bayes Theorem; Diabetes Mellitus; Hospital Mortality; Humans; Lactic Acid; Machine Learning; Sepsis | 2022 |
Machine learning models to predict in-hospital mortality in septic patients with diabetes.
Topics: Bayes Theorem; Diabetes Mellitus; Hospital Mortality; Humans; Lactic Acid; Machine Learning; Sepsis | 2022 |
Machine learning models to predict in-hospital mortality in septic patients with diabetes.
Topics: Bayes Theorem; Diabetes Mellitus; Hospital Mortality; Humans; Lactic Acid; Machine Learning; Sepsis | 2022 |
Machine learning models to predict in-hospital mortality in septic patients with diabetes.
Topics: Bayes Theorem; Diabetes Mellitus; Hospital Mortality; Humans; Lactic Acid; Machine Learning; Sepsis | 2022 |
Clinical usefulness of biomarkers for diagnosis and prediction of prognosis in sepsis and septic shock.
Topics: Aged; Biomarkers; Female; Humans; Lactic Acid; Lipopolysaccharide Receptors; Lung Diseases; Male; Pe | 2022 |
Clinical usefulness of biomarkers for diagnosis and prediction of prognosis in sepsis and septic shock.
Topics: Aged; Biomarkers; Female; Humans; Lactic Acid; Lipopolysaccharide Receptors; Lung Diseases; Male; Pe | 2022 |
Clinical usefulness of biomarkers for diagnosis and prediction of prognosis in sepsis and septic shock.
Topics: Aged; Biomarkers; Female; Humans; Lactic Acid; Lipopolysaccharide Receptors; Lung Diseases; Male; Pe | 2022 |
Clinical usefulness of biomarkers for diagnosis and prediction of prognosis in sepsis and septic shock.
Topics: Aged; Biomarkers; Female; Humans; Lactic Acid; Lipopolysaccharide Receptors; Lung Diseases; Male; Pe | 2022 |
PLK1 protects intestinal barrier function in sepsis: A translational research.
Topics: Animals; Endotoxins; Interleukin-6; Intestinal Mucosa; Lactic Acid; Mice; Polo-Like Kinase 1; Sepsis | 2023 |
Hyperlactatemia and altered lactate kinetics are associated with excess mortality in sepsis : A multicenter retrospective observational study.
Topics: Humans; Hyperlactatemia; Kinetics; Lactic Acid; Retrospective Studies; Sepsis | 2023 |
[Therapy of sepsis].
Topics: Fluid Therapy; Humans; Hydrocortisone; Lactic Acid; Resuscitation; Sepsis; Shock, Septic; Vasoconstr | 2023 |
Baseline red blood cell distribution width and perforin, dynamic levels of interleukin 6 and lactate are predictors of mortality in patients with sepsis.
Topics: Erythrocytes; Humans; Intensive Care Units; Interleukin-6; Lactic Acid; Perforin; Prognosis; Retrosp | 2023 |
Introduction of an emergency medicine pharmacist-led sepsis alert response system in the emergency department: A cohort study.
Topics: Australia; Cohort Studies; Emergency Service, Hospital; Hospital Mortality; Humans; Lactic Acid; Pha | 2023 |
Can lactate levels and lactate kinetics predict mortality in patients with COVID-19 with using qCSI scoring system?
Topics: COVID-19; Humans; Kinetics; Lactic Acid; Prognosis; Retrospective Studies; ROC Curve; Sepsis | 2023 |
Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study.
Topics: Humans; Intensive Care Units; Lactic Acid; Nomograms; Prognosis; Respiratory Distress Syndrome; Resp | 2023 |
Topics: Bronchiolitis; Cardiac Surgical Procedures; Disease Progression; Extracorporeal Membrane Oxygenation | 2023 |
How Would You Resuscitate This Patient With Septic Shock? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Topics: Critical Care; Humans; Lactic Acid; Sepsis; Shock, Septic; Teaching Rounds | 2023 |
Clinical Significance of Procalcitonin, Lactic Acid, and Endotoxin Testing for Children With Severe Pneumonia and Sepsis.
Topics: Child; Clinical Relevance; Endotoxins; Humans; Lactic Acid; Pneumonia; Procalcitonin; Retrospective | 2023 |
Analysis of the Effect of a New Type of Nano-drug Carrier Preparation on the Pathological Changes in Lung and Inducible Nitric-Oxide Synthase Expression in Severe Sepsis.
Topics: Animals; Lactic Acid; Lung; Nanoparticles; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; RNA, M | 2022 |
Overcultured? Blood cultures on discharged ED patients were ordered more frequently after the SEP-1 bundle initiation.
Topics: Adult; Blood Culture; Emergency Service, Hospital; Humans; Lactic Acid; Patient Discharge; Retrospec | 2023 |
[Predictive value of early lactate/albumin ratio in the prognosis of sepsis].
Topics: Adult; Albumins; Humans; Interleukin-6; Lactic Acid; Prognosis; Retrospective Studies; Sepsis | 2023 |
Practice and effect evaluation of early restrictive fluid resuscitation strategy in the nursing care of patients with sepsis in the emergency department: a retrospective cohort study.
Topics: Emergency Service, Hospital; Humans; Lactic Acid; Nursing Care; Respiratory Distress Syndrome; Retro | 2023 |
End-to-End Sepsis Solution Incorporating Expert Telemedicine Consultation.
Topics: Adult; Aged; Aged, 80 and over; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Midd | 2023 |
Serial evaluation of the serum lactate level with the SOFA score to predict mortality in patients with sepsis.
Topics: Humans; Intensive Care Units; Lactic Acid; Organ Dysfunction Scores; Prognosis; Prospective Studies; | 2023 |
In Patients With Sepsis, Initial Lactate Clearance Is Confounded Highly by Comorbidities and Poorly Predicts Subsequent Lactate Trajectory.
Topics: Humans; Lactic Acid; Sepsis | 2023 |
[Ability of qSOFA1-lactate to predict 30-day mortality in patients seen for infection in the Emergency Department].
Topics: Emergency Service, Hospital; Female; Hospital Mortality; Humans; Lactic Acid; Male; Organ Dysfunctio | 2023 |
Mean Serum Lactate Levels in Patients with Sepsis Presenting to the Department of Emergency Medicine of a Tertiary Care Center: A Descriptive Cross-sectional Study.
Topics: Cross-Sectional Studies; Emergency Medicine; Female; Humans; Lactic Acid; Male; Sepsis; Tertiary Car | 2023 |
[Protective Effect of Mesenchymal Stem Cell Transplantation on Intestinal Injury in Septic Mice and Its Mechanism].
Topics: Animals; Interleukin-10; Interleukin-6; Lactic Acid; Mesenchymal Stem Cell Transplantation; Mice; Oc | 2023 |
Unmeasured Organic Anions as Predictors of Clinical Outcomes in Lactic Acidosis due to Sepsis.
Topics: Acidosis, Lactic; Adult; Albumins; Anions; Humans; Lactic Acid; Retrospective Studies; ROC Curve; Se | 2023 |
CLINICAL CHARACTERISTICS AND PREDICTORS OF MORTALITY DIFFER BETWEEN PULMONARY AND ABDOMINAL SEPSIS.
Topics: Acute Kidney Injury; Adult; Humans; Intraabdominal Infections; Lactic Acid; Lipopolysaccharide Recep | 2023 |
Parthanatos type programmed cell death and septic patient mortality.
Topics: Apoptosis; Humans; Lactic Acid; Parthanatos; Prognosis; Prospective Studies; Sepsis | 2023 |
The Effect of Fluid Resuscitation Timing in Early Sepsis Resuscitation.
Topics: Adult; Fluid Therapy; Humans; Hypotension; Lactic Acid; Resuscitation; Retrospective Studies; Sepsis | 2023 |
[Prognostic value of serum sodium variability within 72 hours and lactic acid combined with severity score in patients with sepsis].
Topics: Humans; Lactic Acid; Prognosis; Retrospective Studies; Sepsis; Sodium | 2023 |
Do prehospital sepsis alerts decrease time to complete CMS sepsis measures?
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Centers for Medicare and Medicaid Services, U.S.; Em | 2023 |
Sepsis biomarkers for early diagnosis of bacteremia in emergency department.
Topics: Adult; Bacteremia; Biomarkers; C-Reactive Protein; Calcitonin; Early Diagnosis; Emergency Service, H | 2023 |
Effect of Norepinephrine on Peripheral Perfusion Index and Its Association With the Prognosis of Patients With Sepsis.
Topics: Humans; Intensive Care Units; Lactic Acid; Norepinephrine; Perfusion Index; Prognosis; Retrospective | 2024 |
PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation.
Topics: Acute Kidney Injury; Apoptosis; Humans; Lactic Acid; Mitochondrial Proteins; Sepsis; Sirtuin 3 | 2023 |
ATF4 knockdown in macrophage impairs glycolysis and mediates immune tolerance by targeting HK2 and HIF-1α ubiquitination in sepsis.
Topics: Activating Transcription Factor 4; Animals; Cytokines; Glycolysis; Hexokinase; Hypoxia-Inducible Fac | 2023 |
Prognostic Importance of Lactate and Blood Gas Parameters in Predicting Mortality in Patients with Critical Malignancies.
Topics: Emergency Service, Hospital; Humans; Lactic Acid; Neoplasms; Prognosis; Prospective Studies; Retrosp | 2023 |
Dynamic changes in lactate levels within the first 24 hours in septic patients as a prognostic indicator: A retrospective cohort study utilizing latent class growth analysis.
Topics: Critical Care; Humans; Lactic Acid; Prognosis; Retrospective Studies; Sepsis | 2023 |
Early Lactate/Albumin and Procalcitonin/Albumin Ratios as Predictors of 28-Day Mortality in ICU-Admitted Sepsis Patients: A Retrospective Cohort Study.
Topics: Adult; Albumins; Humans; Intensive Care Units; Lactic Acid; Organ Dysfunction Scores; Procalcitonin; | 2023 |
[Analysis of clinical characteristics and risk factors of early heat stroke-related acute liver injury].
Topics: Alanine Transaminase; Creatine Kinase; Creatine Kinase, MB Form; Heat Stroke; Humans; Interleukin-6; | 2023 |
EARLY DECREASED RESPIRATORY CHAIN CAPACITY IN RESUSCITATED EXPERIMENTAL SEPSIS IS A MAJOR CONTRIBUTOR TO LACTATE PRODUCTION.
Topics: Animals; Cyanides; Electron Transport; Lactic Acid; Oxygen; Sepsis; Swine | 2023 |
Frequent temporal patterns of physiological and biological biomarkers and their evolution in sepsis.
Topics: Biomarkers; Humans; Lactic Acid; Sepsis | 2023 |
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology.
Topics: Acute Lung Injury; Animals; C-Reactive Protein; HMGB1 Protein; Lactic Acid; Papaverine; Radiology; R | 2023 |
Evaluating of neonatal early onset sepsis through lactate and base excess monitoring.
Topics: Blood Gas Analysis; Case-Control Studies; Cone-Rod Dystrophies; Humans; Infant, Newborn; Lactic Acid | 2023 |
A nomogram for predicting sepsis-associated delirium: a retrospective study in MIMIC III.
Topics: Humans; Lactic Acid; Nomograms; Retrospective Studies; Sepsis; Sepsis-Associated Encephalopathy | 2023 |
The value of right ventricular ultrasound assessment and cardiac biomarkers in the prognosis of sepsis.
Topics: Biomarkers; Humans; Lactic Acid; Natriuretic Peptide, Brain; Peptide Hormones; Procalcitonin; Progno | 2023 |
Hypoxia-inducible factor-1α is a biomarker for predicting patients with sepsis.
Topics: Biomarkers; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intensive Care Units; Lactic Acid; Pr | 2023 |
Diagnosis of septic shock by serum measurement of human neutrophil lipocalin by a rapid homogeneous assay.
Topics: Biomarkers; C-Reactive Protein; Humans; Lactic Acid; Lipocalins; Neutrophils; Procalcitonin; Prognos | 2023 |
Can lactate be valuable in early diagnosis and prognosis of neonatal sepsis?
Topics: C-Reactive Protein; Early Diagnosis; Humans; Infant, Newborn; Lactic Acid; Neonatal Sepsis; Prognosi | 2023 |
[Prognostic value of hemoglobin-to-red cell distribution width ratio in patients with cardiopulmonary resuscitation after out-of-hospital cardiac arrest].
Topics: Cardiopulmonary Resuscitation; Erythrocyte Indices; Hemoglobins; Humans; Intensive Care Units; Lacti | 2023 |
An analysis of lactate/albumin, procalcitonin/albumin, and blood urea nitrogen/albumin ratios as a predictor of mortality in uroseptic patients.
Topics: Aged; Blood Urea Nitrogen; Female; Humans; Lactic Acid; Male; Procalcitonin; Prognosis; Retrospectiv | 2023 |
Risk factors for death caused by early onset sepsis in neonates: a retrospective cohort study.
Topics: Birth Weight; Heart Failure; Humans; Infant; Infant, Newborn; Lactic Acid; Prognosis; Retrospective | 2023 |
Venous blood lactate concentrations in patients with shock: Interesting but not really helpful.
Topics: Humans; Lactic Acid; Resuscitation; Sepsis; Shock; Veins | 2020 |
Persistently elevated early warning scores and lactate identifies patients at high risk of mortality in suspected sepsis.
Topics: Adult; Aged; Critical Care; Critical Illness; Early Warning Score; Female; Hospital Mortality; Human | 2020 |
[Assessment values of procalcitonin, lactic acid, and disease severity scores in patients with sepsis].
Topics: APACHE; Humans; Lactic Acid; Organ Dysfunction Scores; Procalcitonin; Prognosis; ROC Curve; Sepsis | 2019 |
Prognostic value of serial lactate levels in septic patients with and without shock.
Topics: Aged; Aged, 80 and over; Female; Hospitalization; Humans; Lactic Acid; Male; Middle Aged; Organ Dysf | 2019 |
Prognostic performance of pancreatic stone protein in critically ill patients with sepsis.
Topics: Aged; Biomarkers; Critical Illness; Female; Humans; Lactic Acid; Lithostathine; Male; Middle Aged; O | 2019 |
Presepsin versus other biomarkers to predict sepsis and septic shock in patients with infection defined by Sepsis-3 criteria: the PREDI study of diagnostic accuracy.
Topics: Aged; Area Under Curve; Bacteremia; Biomarkers; C-Reactive Protein; Emergency Service, Hospital; Fem | 2019 |
The Use of Procalcitonin as a Sepsis Marker in a Community Hospital.
Topics: Aged; Anti-Bacterial Agents; Biomarkers; Blood Culture; Case-Control Studies; Costs and Cost Analysi | 2019 |
The Combined SIRS + qSOFA (qSIRS) Score is More Accurate Than qSOFA Alone in Predicting Mortality in Patients with Surgical Sepsis in an LMIC Emergency Department.
Topics: Adult; Area Under Curve; Developing Countries; Emergency Service, Hospital; Female; Hospital Mortali | 2020 |
Early lactate measurement is associated with better outcomes in septic patients with an elevated serum lactate level.
Topics: Aged; Female; Humans; Intensive Care Units; Lactic Acid; Logistic Models; Male; Middle Aged; Odds Ra | 2019 |
Lactate up-regulates the expression of PD-L1 in kidney and causes immunosuppression in septic Acute Renal Injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; B7-H1 Antigen; Disease Models, Animal; Epithelial Cells; Im | 2021 |
Efficacy and safety of acupuncture as a complementary therapy for sepsis: A protocol of systematic review and meta-analysis.
Topics: Acupuncture Therapy; APACHE; C-Reactive Protein; HLA-DR Antigens; Humans; Interleukin-10; Interleuki | 2019 |
Beta-blockers' effect on Levels of Lactate in patients with suspected sepsis - The BeLLa study.
Topics: Adrenergic beta-Antagonists; Aged; Case-Control Studies; Emergency Service, Hospital; Female; Humans | 2020 |
Determination of physiological lactate and pH by Raman spectroscopy.
Topics: Humans; Hydrogen-Ion Concentration; Lactic Acid; Reproducibility of Results; Sepsis; Spectrum Analys | 2019 |
Inhaled Albuterol Use and Impaired Lactate Clearance in Patients With Sepsis: A Retrospective Cohort Study.
Topics: Administration, Inhalation; Adult; Albuterol; Hospital Mortality; Humans; Lactic Acid; Retrospective | 2021 |
Evaluation of 2 Rat Models for Sepsis Developed by Improved Cecal Ligation/Puncture or Feces Intraperitoneal-Injection.
Topics: Animals; Cecum; Disease Models, Animal; Feces; Injections, Intraperitoneal; Interleukin-6; Intestine | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Evidence-Based Medicine; Fluid Therapy; | 2020 |
Lactate Measurements and Their Association With Mortality in Pediatric Severe Sepsis in India: Evidence That 6-Hour Level Performs Best.
Topics: Child; Emergency Service, Hospital; Hospitals, Teaching; Humans; India; Lactic Acid; Prognosis; Pros | 2021 |
Thiamine status and lactate concentration in sepsis: A prospective observational study.
Topics: Adult; Aged; Female; Humans; Intensive Care Units; Lactic Acid; Male; Middle Aged; Prospective Studi | 2020 |
Usefulness of presepsin as diagnostic and prognostic marker of sepsis in daily clinical practice.
Topics: APACHE; Area Under Curve; Biomarkers; Case-Control Studies; Female; Humans; Lactic Acid; Lipopolysac | 2019 |
Inflammation-targeting polymeric nanoparticles deliver sparfloxacin and tacrolimus for combating acute lung sepsis.
Topics: Animals; Anti-Bacterial Agents; Drug Carriers; Endothelial Cells; Fluoroquinolones; Gram-Negative Ba | 2020 |
Added value of serial bio-adrenomedullin measurement in addition to lactate for the prognosis of septic patients admitted to ICU.
Topics: Adrenomedullin; Humans; Intensive Care Units; Lactic Acid; Prognosis; Prospective Studies; Sepsis; S | 2020 |
Lactate indices as predictors of in-hospital mortality or 90-day survival after admission to an intensive care unit in unselected critically ill patients.
Topics: Aged; APACHE; Biomarkers; Cohort Studies; Comorbidity; Critical Illness; Female; Hospital Mortality; | 2020 |
Usefulness of infection biomarkers for diagnosing bacteremia in patients with a sepsis code in the emergency department.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Area Under Curve; Bacteremia; Biomarkers; C-Reactive Protei | 2020 |
MR- proADM to detect specific types of organ failure in infection.
Topics: Adrenomedullin; Aged; Aged, 80 and over; Area Under Curve; Blood Coagulation Disorders; C-Reactive P | 2020 |
Sepsis Mandates Help Clinicians and Patients.
Topics: Anti-Bacterial Agents; Centers for Medicare and Medicaid Services, U.S.; Fluid Therapy; Humans; Lact | 2020 |
A mortality analysis of septic shock, vasoplegic shock and cryptic shock classified by the third international consensus definitions (Sepsis-3).
Topics: Consensus; Humans; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2020 |
STAPLAg: a convenient early warning score for use in infected patients in the intensive care unit.
Topics: Age Factors; Aged; Early Warning Score; Female; Humans; Intensive Care Units; Lactic Acid; Lymphocyt | 2020 |
NEWS and qSIRS superior to qSOFA in the prediction of 30-day mortality in emergency department patients in Hong Kong.
Topics: Aged; Aged, 80 and over; Area Under Curve; Consensus; Early Warning Score; Emergency Service, Hospit | 2020 |
Circular RNA circ_0001105 protects the intestinal barrier of septic rats by inhibiting inflammation and oxidative damage and YAP1 expression.
Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis Regulatory Proteins; Down-Regulation; Inflamma | 2020 |
Liver cirrhosis affects serum lactate level measurement while assessing disease severity in patients with sepsis.
Topics: Humans; Lactic Acid; Liver Cirrhosis; Prognosis; Retrospective Studies; ROC Curve; Sepsis; Severity | 2021 |
The predictive value of variables measurable in the ambulance and the development of the Predict Sepsis screening tools: a prospective cohort study.
Topics: Aged; Aged, 80 and over; Ambulances; Blood Pressure; Body Temperature; Cohort Studies; Consciousness | 2020 |
Optimized sensitive and inexpensive method to measure D-lactate as a surrogate marker of methylglyoxal fluxes in metabolically relevant contexts.
Topics: Biomarkers; Colorimetry; Humans; Lactic Acid; Pyruvaldehyde; Sepsis | 2022 |
Sepsis and the Obesity Paradox: Size Matters in More Than One Way.
Topics: Age Factors; Aged; Aged, 80 and over; APACHE; Arterial Pressure; Body Mass Index; Body Weight; Comor | 2020 |
Heparin-binding protein as a biomarker of gastrointestinal dysfunction in critically ill patients: a retrospective cross-sectional study in China.
Topics: Aged; Antimicrobial Cationic Peptides; APACHE; Biomarkers; Blood Proteins; Critical Illness; Cross-S | 2020 |
Impact of Sepsis Mandates on Sepsis Care: Unintended Consequences.
Topics: Anti-Bacterial Agents; Fluid Therapy; Humans; Lactic Acid; Patient Care Bundles; Practice Guidelines | 2020 |
The ability of Procalcitonin, lactate, white blood cell count and neutrophil-lymphocyte count ratio to predict blood stream infection. Analysis of a large database.
Topics: Aged; Biomarkers; C-Reactive Protein; Early Diagnosis; Electronic Health Records; Female; Humans; La | 2020 |
Is lactate lower in septic patients who are prescribed beta blockers? Retrospective cohort study of an intensive care population.
Topics: Cohort Studies; Critical Care; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Male; | 2021 |
Early lactate measurements for predicting in-hospital mortality in paediatric sepsis.
Topics: C-Reactive Protein; Child; Diagnostic Tests, Routine; Hospital Mortality; Humans; Lactic Acid; Progn | 2020 |
Association Between the Oxygen Consumption: Lactate Ratio and Survival in Critically Ill Patients With Sepsis.
Topics: Aged; Critical Illness; Female; Hospital Mortality; Humans; Lactic Acid; Male; Middle Aged; Oxygen C | 2021 |
How to interpret lactate.
Topics: Diagnostic Tests, Routine; Humans; Lactic Acid; Sepsis | 2021 |
Peritonitis-associated hyperlactatemia for evaluating mortality in secondary peritonitis.
Topics: Humans; Hyperlactatemia; Lactic Acid; Peritonitis; Prognosis; Sepsis | 2020 |
Development, Validation, and Clinical Utility Assessment of a Prognostic Score for 1-Year Unplanned Rehospitalization or Death of Adult Sepsis Survivors.
Topics: Adult; Causality; Critical Care; England; Female; Hemoglobins; Hospital Mortality; Hospitalization; | 2020 |
Identification and Quantitative Determination of Lactate Using Optical Spectroscopy-Towards a Noninvasive Tool for Early Recognition of Sepsis.
Topics: Humans; Lactic Acid; Least-Squares Analysis; Multivariate Analysis; Sepsis; Spectroscopy, Near-Infra | 2020 |
Accuracy of a Modified qSOFA Score for Predicting Critical Care Admission in Febrile Children.
Topics: Adolescent; C-Reactive Protein; Child; Confidence Intervals; Critical Care; Female; Fever; Humans; L | 2020 |
Evaluating the implementation and outcomes of a sepsis pathway in the emergency department.
Topics: Anti-Bacterial Agents; Emergency Service, Hospital; Humans; Intensive Care Units; Lactic Acid; Lengt | 2020 |
Analysis of the clinical characteristics of 77 COVID-19 deaths.
Topics: Age Factors; Aged; Aged, 80 and over; C-Reactive Protein; Cause of Death; China; Comorbidity; Corona | 2020 |
Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.
Topics: Acute Kidney Injury; Aged; Alanine Transaminase; Bilirubin; Blood Urea Nitrogen; Comorbidity; Creati | 2020 |
Utilization of a multidisciplinary emergency department sepsis huddle to reduce time to antibiotics and improve SEP-1 compliance.
Topics: Aged; Anti-Bacterial Agents; Blood Culture; Centers for Medicare and Medicaid Services, U.S.; Checkl | 2020 |
Clinical validation demonstrates concordance of qSOFA and POC lactate Bayesian model: Results from the ACDC Phase-2 program.
Topics: Bayes Theorem; Clinical Decision Rules; Female; Humans; Intensive Care Units; Lactic Acid; Male; Org | 2021 |
Can capillary lactate improve early warning scores in emergency department? An observational, prospective, multicentre study.
Topics: Early Warning Score; Emergency Service, Hospital; Hospital Mortality; Humans; Lactic Acid; Organ Dys | 2021 |
Lactate Suppresses Macrophage Pro-Inflammatory Response to LPS Stimulation by Inhibition of YAP and NF-κB Activation
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Inflammatory Agents; Cells, Cultured; Inflammati | 2020 |
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
Topics: Acetyl Coenzyme A; Animals; Citric Acid Cycle; Dichloroacetic Acid; Drosophila melanogaster; Glycoly | 2020 |
The sensitivity of qSOFA calculated at triage and during emergency department treatment to rapidly identify sepsis patients.
Topics: Adult; Aged; Biomarkers; Databases, Factual; Emergency Service, Hospital; Female; Hospital Mortality | 2020 |
Mortality prediction using a novel combination of biomarkers in the first day of sepsis in intensive care units.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Humans; Intensive Care Units; Interleukin-6; Internatio | 2021 |
Inhibition of aerobic glycolysis alleviates sepsis‑induced acute kidney injury by promoting lactate/Sirtuin 3/AMPK‑regulated autophagy.
Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Autophagy; Deoxyglucose; Glycolysis; La | 2021 |
[Clinical study of D-lactate and intestinal fatty acid binding protein in evaluating disease severity and prognosis of ICU patients: secondary analysis of a prospective, multicenter clinical study].
Topics: China; Fatty Acid-Binding Proteins; Humans; Intensive Care Units; Lactic Acid; Prognosis; Prospectiv | 2020 |
Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antivira | 2021 |
Early hemodynamic assessment using NICOM in patients at risk of developing Sepsis immediately after emergency department triage.
Topics: Adult; Aged; Cardiac Output; Emergency Service, Hospital; Female; Heart Rate; Humans; Lactic Acid; M | 2021 |
The Levels of Lactate, Troponin, and N-Terminal Pro-B-Type Natriuretic Peptide Are Predictors of Mortality in Patients with Sepsis and Septic Shock: A Retrospective Cohort Study.
Topics: Biomarkers; Humans; Lactic Acid; Natriuretic Peptide, Brain; Peptide Fragments; Retrospective Studie | 2021 |
Prognostic Accuracy of VqSOFA for Predicting 28-day Mortality in Patients with Suspected Sepsis in the Emergency Department.
Topics: Aged; Cohort Studies; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Lactic Acid; | 2021 |
A novel biomarker for predicting sepsis mortality: SCUBE-1.
Topics: Aged; Aged, 80 and over; APACHE; Biomarkers; C-Reactive Protein; Calcium-Binding Proteins; Case-Cont | 2021 |
Evaluation of the association between extravascular lung water and prognosis of sepsis: A protocol of systematic review.
Topics: APACHE; Blood Gas Analysis; Blood Pressure; Capillary Permeability; Cardiac Output; Case-Control Stu | 2021 |
Impact of left ventricular function on tissue perfusion and renal outcomes in patients with sepsis.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Female; Glomerular Filtration Rate; Humans; Lactic Aci | 2021 |
The timing of last hemodialysis influences the prognostic value of serum lactate levels in predicting mortality of end-stage renal disease patients with sepsis in the emergency department.
Topics: Aged; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Kidney Failure, Chronic; Lact | 2021 |
Prognostic value of lactate levels and lactate clearance in sepsis and septic shock with initial hyperlactatemia: A retrospective cohort study according to the Sepsis-3 definitions.
Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Emergency Service, Hospital; Female; Huma | 2021 |
Serum Lactate Testing to Predict Mortality in Patients with Sepsis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cause of Death; Diagnostic Techniques and Procedures; Fe | 2021 |
Combining Blood-Based Biomarkers to Predict Mortality of Sepsis at Arrival at the Emergency Department.
Topics: Adult; Aged; Area Under Curve; Biomarkers; China; Emergency Service, Hospital; Female; Humans; Inter | 2021 |
Lactate/albumin ratio is more effective than lactate or albumin alone in predicting clinical outcomes in intensive care patients with sepsis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Critical Illness; Female; Humans; Intensive Care Units; | 2021 |
Initial lactate levels versus lactate clearance for predicting mortality in sepsis: A prospective observational analytical study.
Topics: Adolescent; Humans; Lactic Acid; Prognosis; Prospective Studies; Resuscitation; Retrospective Studie | 2021 |
Clinical evaluation of a novel subcutaneous lactate monitor.
Topics: Critical Care; Female; Humans; Lactic Acid; Male; Monitoring, Physiologic; Sepsis; Shock | 2022 |
Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis.
Topics: Alanine; Animals; Gluconeogenesis; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats | 2021 |
The agreement between arterial and venous lactate in patients with sepsis.
Topics: Humans; Intensive Care Units; Lactic Acid; Oximetry; Sepsis; Shock, Septic | 2021 |
Evaluation of the quick sequential organ failure assessment score plus lactate in critically ill dogs.
Topics: Animals; Critical Illness; Dog Diseases; Dogs; Hospital Mortality; Intensive Care Units; Lactic Acid | 2021 |
Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis.
Topics: Animals; Glucocorticoids; Hyperlactatemia; Lactic Acid; Mice; Receptors, Glucocorticoid; Sepsis; Vas | 2021 |
Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis.
Topics: Acetylation; HMGB1 Protein; Humans; Lactic Acid; Macrophages; Sepsis | 2022 |
Evolving cutoff values of "hyperlactatemia" and the role of infection.
Topics: Acidosis, Lactic; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Shock, Septic | 2017 |
Authors respond to Both qSOFA score and bedside plasma lactate are the predictors of mortality for patients with infections in ED.
Topics: Humans; Lactic Acid; Organ Dysfunction Scores; Sepsis | 2017 |
Association Between Hospital Case Volume of Sepsis, Adherence to Evidence-Based Processes of Care and Patient Outcomes.
Topics: Aged; Aged, 80 and over; Clinical Protocols; Evidence-Based Practice; Female; Guideline Adherence; H | 2017 |
Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis.
Topics: Animals; Cardiomyopathies; Cytokines; Deoxyglucose; Disease Models, Animal; Glycolysis; Heart; Hexok | 2017 |
Procalcitonin for the early diagnosis of sepsis in burn patients: A retrospective study.
Topics: Adult; Aged; Body Temperature; Burns; C-Reactive Protein; Calcitonin; Case-Control Studies; Early Di | 2017 |
Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis.
Topics: Animals; Blood Gas Analysis; C-Reactive Protein; Cohort Studies; Disease Models, Animal; Hemodynamic | 2017 |
Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients.
Topics: Biomarkers; Calcitonin; Emergency Service, Hospital; Humans; Lactic Acid; Leukocyte Count; Odds Rati | 2017 |
Blockage of glycolysis by targeting PFKFB3 alleviates sepsis-related acute lung injury via suppressing inflammation and apoptosis of alveolar epithelial cells.
Topics: A549 Cells; Acute Lung Injury; Alveolar Epithelial Cells; Animals; Anti-Inflammatory Agents, Non-Ste | 2017 |
Arterial versus venous lactate: a measure of sepsis in children.
Topics: Adolescent; Arteries; Biomarkers; Child; Child, Preschool; Female; Humans; Hydrogen-Ion Concentratio | 2017 |
Biochemical-immunological hybrid biosensor based on two-dimensional chromatography for on-site sepsis diagnosis.
Topics: Biosensing Techniques; C-Reactive Protein; Calcitonin; Chromatography; Humans; Immunoassay; Lactic A | 2017 |
Venous vs Arterial Lactate and 30-Day Mortality in Pediatric Sepsis.
Topics: Arteries; Child; Humans; Lactic Acid; Sepsis; Veins | 2017 |
Venous vs Arterial Lactate and 30-Day Mortality in Pediatric Sepsis-Reply.
Topics: Arteries; Child; Humans; Lactic Acid; Sepsis; Veins | 2017 |
Clinical predictors of early death from sepsis.
Topics: Adult; Aged; Disease Progression; Emergency Service, Hospital; Female; Hospitalization; Humans; Lact | 2017 |
Muscle oxygenation as an indicator of shock severity in patients with suspected severe sepsis or septic shock.
Topics: Adult; Aged; Blood Pressure; Case-Control Studies; Female; Hand; Heart Rate; Humans; Intensive Care | 2017 |
[Before-after study of the effect of implementing a sepsis code for emergency departments in the community of Aragon].
Topics: Anti-Bacterial Agents; Blood Culture; Controlled Before-After Studies; Disease Management; Emergency | 2017 |
The influence of a change in septic shock definitions on intensive care epidemiology and outcome: comparison of sepsis-2 and sepsis-3 definitions.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Critical Care; Female; Guidelines as Topic; Hospital | 2018 |
Blood pressure variability as an indicator of sepsis severity in adult emergency department patients.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Determination; Emergency Service, Hospital; Female; Flui | 2018 |
Impact of an emergency department electronic sepsis surveillance system on patient mortality and length of stay.
Topics: Adult; Aged; Alert Fatigue, Health Personnel; Emergency Service, Hospital; Female; Hospital Mortalit | 2018 |
Which one is a better predictor of ICU mortality in septic patients? Comparison between serial serum lactate concentrations and its removal rate.
Topics: Adult; Aged; Aged, 80 and over; Blood Gas Analysis; Female; Humans; Intensive Care Units; Lactic Aci | 2018 |
Change in Lactate Levels After Hemodialysis in Patients With End-Stage Renal Disease.
Topics: Biomarkers; Emergency Service, Hospital; False Negative Reactions; False Positive Reactions; Female; | 2018 |
Importance of measuring lactate levels in children with sepsis.
Topics: Acidosis; Adolescent; Biomarkers; Child; Child, Preschool; Female; Humans; Lactic Acid; Male; Resusc | 2017 |
Sustained high serum caspase-3 concentrations and mortality in septic patients.
Topics: Aged; Apoptosis; Caspase 3; Female; Humans; Intensive Care Units; Kaplan-Meier Estimate; Keratin-18; | 2018 |
Lactate improves SAPS 3 prognostication.
Topics: Adult; Aged; Critical Care; Female; Heart Arrest; Hospital Mortality; Humans; Lactic Acid; Male; Mid | 2018 |
Serum anion gap predicts lactate poorly, but may be used to identify sepsis patients at risk for death: A cohort study.
Topics: Acid-Base Equilibrium; Adult; Aged; Biomarkers; Cohort Studies; Emergency Service, Hospital; Female; | 2018 |
Lactate ≥2 mmol/L plus qSOFA improves utility over qSOFA alone in emergency department patients presenting with suspected sepsis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Australia; Cohort Studies; Emergency Service, Hospital; | 2017 |
Choice of resuscitative fluids and mortality in emergency department patients with sepsis.
Topics: Aged; Aged, 80 and over; Comorbidity; Emergency Service, Hospital; Female; Fluid Therapy; Hospital M | 2018 |
Effect of platelet-lymphocyte ratio and lactate levels obtained on mortality with sepsis and septic shock.
Topics: Blood Pressure; Blood Urea Nitrogen; Emergency Service, Hospital; Glasgow Coma Scale; Hospital Morta | 2018 |
Another failure in predicting sepsis outcomes in the emergency department.
Topics: Biomarkers; Emergency Service, Hospital; Humans; Lactic Acid; Lymphocyte Count; Platelet Count; Prog | 2018 |
The utility of presepsin in diagnosis and risk stratification for the emergency patients with sepsis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Biomarkers; Case-Control Studies; Emergency Serv | 2018 |
Determination of plasma lactate in the emergency department for the early detection of tissue hypoperfusion in septic patients.
Topics: Adult; Aged; Biomarkers; Early Diagnosis; Emergency Medical Services; Female; Humans; Lactic Acid; L | 2018 |
Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock.
Topics: Aged; Anti-Bacterial Agents; Blood Culture; Crystalloid Solutions; Female; Hospital Mortality; Human | 2018 |
Serum lactate cut-offs as
Topics: Aged; Aged, 80 and over; Algorithms; Anti-Bacterial Agents; Biomarkers; Clinical Protocols; Decision | 2018 |
Management and outcomes of patients presenting with sepsis and septic shock to the emergency department during nursing handover: a retrospective cohort study.
Topics: Anti-Bacterial Agents; Blood Culture; Emergency Service, Hospital; Hospital Mortality; Humans; Lacti | 2018 |
Prognostic Value of The Lactate/Albumin Ratio for Predicting 28-Day Mortality in Critically ILL Sepsis Patients.
Topics: Aged; Albumins; Critical Illness; Female; Humans; Lactic Acid; Male; Middle Aged; Prognosis; Retrosp | 2018 |
Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa.
Topics: Africa, Eastern; Child; Child, Preschool; Critical Illness; Female; Fever; Humans; Infant; Lactic Ac | 2018 |
Lactate POCT in mobile intensive care units for septic patients? A comparison of capillary blood method versus venous blood and plasma-based reference methods.
Topics: Blood Chemical Analysis; Female; Humans; Intensive Care Units; Lactic Acid; Male; Point-of-Care Syst | 2018 |
Helpful Only When Elevated: Initial Serum Lactate in Stable Emergency Department Patients with Sepsis Is Specific, but Not Sensitive for Future Deterioration.
Topics: Adult; Aged; Biomarkers; Cohort Studies; Emergency Service, Hospital; Female; Humans; Lactic Acid; M | 2018 |
Relocation of blood gas laboratory to the emergency department helps decrease lactic acid values.
Topics: Biomarkers; Blood Gas Analysis; Creatinine; Emergency Service, Hospital; Female; Hospital Design and | 2018 |
Difference between elderly and non-elderly patients in using serum lactate level to predict mortality caused by sepsis in the emergency department.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biomarkers; Blood Culture; Comor | 2018 |
Risk factors and outcomes of sepsis-induced myocardial dysfunction and stress-induced cardiomyopathy in sepsis or septic shock: A comparative retrospective study.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Cytokines; Diabetes Mellitus; Echocar | 2018 |
Serum lactate predicts resource utilization, but not surgical need, in the emergency department.
Topics: Abdominal Pain; Adult; Aged; Biomarkers; Emergency Medical Services; Emergency Service, Hospital; Eq | 2018 |
Activation of a code sepsis in the emergency department is associated with a decrease in mortality.
Topics: Aged; Analysis of Variance; Anti-Bacterial Agents; Biomarkers; Clinical Protocols; Cohort Studies; C | 2019 |
Application of the new Sepsis-3 definition in a cohort of patients with severe sepsis and septic shock admitted to Intensive Care Unit from the Emergency Department.
Topics: Adult; Aged; Cohort Studies; Female; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; | 2019 |
Comparison of qSOFA with current emergency department tools for screening of patients with sepsis for critical illness.
Topics: Adult; Aged; Area Under Curve; Biomarkers; Cohort Studies; Communicable Diseases; Critical Illness; | 2018 |
Predictive Validity of Sepsis-3 Definitions and Sepsis Outcomes in Critically Ill Patients: A Cohort Study in 49 ICUs in Argentina.
Topics: Adult; Aged; Argentina; Cohort Studies; Comorbidity; Critical Illness; Drug Resistance, Microbial; F | 2018 |
The ten pitfalls of lactate clearance in sepsis.
Topics: Humans; Lactic Acid; Liver Diseases; Metabolic Clearance Rate; Sepsis | 2019 |
The Surviving Sepsis Campaign Bundle: 2018 Update.
Topics: Anti-Bacterial Agents; Fluid Therapy; Health Promotion; Humans; Lactic Acid; Microbial Sensitivity T | 2018 |
Septic acute kidney injury patients in emergency department: The risk factors and its correlation to serum lactate.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Emergency Service, Hospital; | 2019 |
The Preseptic Period and Inflammatory Markers in the Prediction of the Course of Sepsis.
Topics: Bacteria; Biomarkers; Bronchoalveolar Lavage Fluid; Calcitonin; Case-Control Studies; Demography; Di | 2018 |
Early increases in serum FGF21 levels predict mortality of septic patients.
Topics: Aged; Biomarkers; C-Reactive Protein; Female; Fibroblast Growth Factors; Humans; Intensive Care Unit | 2018 |
The 11th pitfall: thiamine deficiency.
Topics: Humans; Lactic Acid; Sepsis; Thiamine Deficiency | 2018 |
Predictive value of serum albumin levels on noradrenaline and fluid requirements in the first 24 h after admission to the Intensive Care Unit - A prospective observational study.
Topics: Aged; Aged, 80 and over; Arterial Pressure; C-Reactive Protein; Critical Care; Electronic Health Rec | 2018 |
Effect of electroacupuncture at ST36 on the intestinal mucosal mechanical barrier and expression of occludin in a rat model of sepsis.
Topics: Acupuncture Points; Animals; Disease Models, Animal; Electroacupuncture; Humans; Intestinal Mucosa; | 2018 |
Effect of Thiamine Administration on Lactate Clearance and Mortality in Patients With Septic Shock.
Topics: Adult; Aged; Cohort Studies; Critical Illness; Female; Follow-Up Studies; Humans; Intensive Care Uni | 2018 |
THE ROLE OF PROCALCITONIN AND BLOOD LACTIC ACID VALUES IN PROGNOSIS OF SEPSIS AND SEPTIC SHOCK IN POLYTRAUMA PATIENTS.
Topics: Biomarkers; C-Reactive Protein; Humans; Lactic Acid; Multiple Trauma; Procalcitonin; Prognosis; Seps | 2018 |
Diagnostic and prognostic value of procalcitonin in patients with sepsis.
Topics: Area Under Curve; Bacteremia; Bacteria; Biomarkers; Blood Culture; C-Reactive Protein; Calcitonin; H | 2018 |
Lactic Acidosis in a Critically Ill Patient: Not Always Sepsis.
Topics: Acidosis, Lactic; Antineoplastic Agents; Child; Critical Illness; Diagnosis, Differential; Fatal Out | 2018 |
SEP-1: The Lactate Myth and Other Fairytales.
Topics: Humans; Lactic Acid; Retrospective Studies; Sepsis | 2018 |
Does Timing Matter? Using Lactate to Predict Outcomes in Sepsis.
Topics: Emergency Service, Hospital; Humans; Lactic Acid; Sepsis; Shock, Septic | 2018 |
Resuscitation of Septic Patients with Target-and-endpoint Protocol: A Retrospective Study from a Chinese Tertiary Hospital ICU.
Topics: APACHE; Arterial Pressure; Central Venous Pressure; Endpoint Determination; Female; Hemodynamics; Hu | 2018 |
Prehospital sepsis alert notification decreases time to initiation of CMS sepsis core measures.
Topics: Aged; Anti-Bacterial Agents; Blood Culture; Centers for Medicare and Medicaid Services, U.S.; Emerge | 2019 |
Early recognition of sepsis through emergency medical services pre-hospital screening.
Topics: Aged; Anti-Bacterial Agents; Blood Culture; Emergency Medical Services; Emergency Service, Hospital; | 2019 |
Sepsis alerts in EMS and the results of pre-hospital ETCO2.
Topics: Adult; Aged; Biomarkers; Carbon Dioxide; Emergency Medical Services; Female; Hospitals, Urban; Human | 2019 |
Prognostic Value of Tissue Oxygen Monitoring and Regional Cerebral Oxygen Saturation Monitoring and Their Correlation in Neurological Patients with Sepsis: A Preliminary, Prospective, Observational Study.
Topics: Adult; Aged; APACHE; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Hospital Mortality; Humans; | 2020 |
Lactate Measurements: A Guide to Therapy or to Quality?
Topics: Aged; Humans; Lactic Acid; Medicaid; Medicare; Sepsis; Shock, Septic; United States | 2018 |
Comparison of Survival Prediction with Single versus Combination Use of Microcirculation End Point Resuscitation in Sepsis and Septic Shock.
Topics: Adult; Aged; Central Venous Pressure; Female; Fluid Therapy; Humans; Indonesia; Intensive Care Units | 2018 |
Development and Evaluation of a Machine Learning Model for the Early Identification of Patients at Risk for Sepsis.
Topics: Aged; Early Diagnosis; Female; Hospitals, Urban; Humans; Lactic Acid; Machine Learning; Male; Middle | 2019 |
SMFM Consult Series #47: Sepsis during pregnancy and the puerperium.
Topics: Anti-Bacterial Agents; Crystalloid Solutions; Culture Techniques; Delivery, Obstetric; Female; Fluid | 2019 |
Does Gender Matter in Septic Patient Outcomes?
Topics: Adult; Aged; Aged, 80 and over; California; Cohort Studies; Comorbidity; Cross-Sectional Studies; Em | 2019 |
Initial clinical outcomes and prognostic variables in the implementation of a Code Sepsis in a high complexity University Hospital.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; APACHE; Biomarkers; Clinical Protocols; Creatinine; Fem | 2019 |
Amino acid derangements in adults with severe falciparum malaria.
Topics: Acidosis; Adult; Amino Acids; Arginine; Bangladesh; Female; Humans; Lactic Acid; Malaria, Falciparum | 2019 |
Prognostic accuracy of the serum lactate level, the SOFA score and the qSOFA score for mortality among adults with Sepsis.
Topics: Aged; Aged, 80 and over; Biomarkers; Critical Care; Databases, Factual; Female; Hospital Mortality; | 2019 |
MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Cells, Cultured; Cytokines; Disease | 2019 |
Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice.
Topics: Animals; Biomarkers; Cardiac Output; Cardiomyopathies; Cytokines; Disease Models, Animal; Disease Pr | 2019 |
Prognostic factors of acute mesenteric ischemia in ICU patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Anticoagulants; Comorbidity; Female; Hospital Mortality; Hum | 2019 |
Lactic Acid Inhibits Lipopolysaccharide-Induced Mast Cell Function by Limiting Glycolysis and ATP Availability.
Topics: Adenosine Triphosphate; Animals; Cytokines; Endotoxemia; Glycolysis; Inflammation; Lactic Acid; Lipo | 2019 |
Arterial vs venous lactate: Correlation and predictive value of mortality of patients with sepsis during early resuscitation phase.
Topics: Arteries; Biomarkers; Female; Hospital Mortality; Humans; Iran; Lactic Acid; Middle Aged; Predictive | 2020 |
Lactate, bicarbonate and anion gap for evaluation of patients presenting with sepsis to the emergency department: A prospective cohort study.
Topics: Acid-Base Equilibrium; Bicarbonates; Biomarkers; Emergency Service, Hospital; Female; Hospital Morta | 2020 |
[Clinical significance on serum intestinal fatty acid binding protein and D-lactic acid levels in early intestinal injury of patients with sepsis].
Topics: Adult; APACHE; Fatty Acid-Binding Proteins; Humans; Intestinal Mucosa; Intestines; Lactic Acid; Prog | 2019 |
Understanding Hyperlactatemia in Human Sepsis: Are We Making Progress?
Topics: Humans; Hyperlactatemia; Lactic Acid; Sepsis | 2019 |
Understanding Hyperlactatemia in Sepsis: Are We There Yet?
Topics: Humans; Hyperlactatemia; Lactic Acid; Sepsis | 2019 |
Predictive value of C-reactive protein and NT-pro-BNP levels in sepsis patients older than 75 years: a prospective, observational study.
Topics: Aged; APACHE; Biomarkers; C-Reactive Protein; Female; Humans; Intensive Care Units; Lactic Acid; Mal | 2020 |
The use of APACHE II, SOFA, SAPS 3, C-reactive protein/albumin ratio, and lactate to predict mortality of surgical critically ill patients: A retrospective cohort study.
Topics: Aged; APACHE; Biomarkers; C-Reactive Protein; Critical Care; Critical Illness; Female; Hospital Mort | 2019 |
Neutrophil-lymphocyte ratio and plasma lactate predict 28-day mortality in patients with sepsis.
Topics: Aged; Biomarkers; C-Reactive Protein; Calcitonin; Female; Humans; Inflammation; Lactic Acid; Lymphoc | 2019 |
Predicting Outcomes in Sepsis.
Topics: Aconitate Hydratase; Goals; Humans; Lactic Acid; Resuscitation; Sepsis; Shock, Septic | 2019 |
Combining qSOFA criteria with initial lactate levels: Improved screening of septic patients for critical illness.
Topics: Aged; Cohort Studies; Critical Illness; Female; Humans; Lactic Acid; Male; Mass Screening; Middle Ag | 2020 |
Nonviral infection-related lymphocytopenia for the prediction of adult sepsis and its persistence indicates a higher mortality.
Topics: Adult; Aged; Area Under Curve; Biomarkers; Early Diagnosis; Humans; Lactic Acid; Leukocyte Count; Ly | 2019 |
Guideline promotes early, aggressive sepsis treatment to boost survival.
Topics: Anti-Bacterial Agents; Critical Care; Emergency Medical Services; Guideline Adherence; Humans; Lacti | 2013 |
Peripheral venous and arterial lactate agreement in septic patients in the emergency department: a pilot study.
Topics: Arteries; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Middle Aged; Pilot Project | 2014 |
Early lactate clearance in septic patients with elevated lactate levels admitted from the emergency department to intensive care: time to aim higher?
Topics: Adult; Aged; Aged, 80 and over; APACHE; Emergency Service, Hospital; Female; Hospital Mortality; Hum | 2013 |
Implications of the new international sepsis guidelines for nursing care.
Topics: Adult; Anti-Bacterial Agents; Blood; Central Venous Pressure; Evidence-Based Nursing; Fluid Therapy; | 2013 |
[Prognostic value of arterial lactate content combined with base excess in patients with sepsis: a retrospective study].
Topics: Adult; Aged; Area Under Curve; Female; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Middle | 2013 |
Lactate clearance for assessing response to resuscitation in severe sepsis.
Topics: Hospital Mortality; Humans; Lactic Acid; Resuscitation; Sepsis; Survival Rate; Treatment Outcome | 2013 |
The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis.
Topics: Aged; APACHE; Biomarkers; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Incidence | 2013 |
Capillary lactic acid validation in an ED.
Topics: Adult; Aged; Arteries; Biomarkers; Blood Specimen Collection; Capillaries; Emergency Service, Hospit | 2013 |
Fluid volume, lactate values, and mortality in sepsis patients with intermediate lactate values.
Topics: Aged; Aged, 80 and over; Cohort Studies; Female; Fluid Therapy; Hospital Mortality; Humans; Lactic A | 2013 |
Timing and appropriateness of initial antibiotic therapy in newly presenting septic patients.
Topics: Anti-Bacterial Agents; Case-Control Studies; Female; Humans; Intensive Care Units; Lactic Acid; Male | 2014 |
Sequential L-lactate concentration in hospitalised equine neonates: A prospective multicentre study.
Topics: Animals; Animals, Newborn; Critical Illness; Horse Diseases; Horses; Humans; Lactic Acid; Prospectiv | 2013 |
Sustained high serum malondialdehyde levels are associated with severity and mortality in septic patients.
Topics: Aged; APACHE; Female; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Male; Malondial | 2013 |
Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study.
Topics: Acute Kidney Injury; Blood Pressure; Disease Progression; Dobutamine; Furosemide; Hemodynamics; Huma | 2013 |
Atorvastatin prevents sepsis-induced downregulation of myocardial β1-adrenoceptors and decreased cAMP response in mice.
Topics: Animals; Atorvastatin; Blotting, Western; Catecholamines; Cyclic AMP; Heptanoic Acids; Lactic Acid; | 2014 |
Prognostic value of central venous oxygen saturation and blood lactate levels measured simultaneously in the same patients with severe systemic inflammatory response syndrome and severe sepsis.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Predict | 2014 |
[The value of combination of the mortality in emergency department sepsis score and blood lactate level in the risk stratification of severe sepsis in the emergency department].
Topics: Aged; Aged, 80 and over; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Middle Aged | 2014 |
The microcirculation is preserved in emergency department low-acuity sepsis patients without hypotension.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Flow Velocity; Case-Control Studies; Emergency Service, H | 2014 |
Infection inspection: screening & managing sepsis in the prehospital setting, part 2 of 2.
Topics: Blood Gas Analysis; Capnography; Carbon Dioxide; Central Venous Pressure; Dopamine Agents; Emergency | 2014 |
Predictors of five days mortality in diabetic ketoacidosis patients: a prospective cohort study.
Topics: Acid-Base Equilibrium; Adult; Aged; Bicarbonates; Blood Glucose; Coma; Diabetic Ketoacidosis; Female | 2014 |
Therapeutic goal achievements during severe sepsis and septic shock resuscitation and their association with patients' outcomes.
Topics: Aged; Female; Humans; Lactic Acid; Male; Middle Aged; Prospective Studies; Resuscitation; Sepsis; Sh | 2014 |
[Validation of a modified early warning score to predict ICU transfer for patients with severe sepsis or septic shock on general wards].
Topics: Aged; APACHE; Blood Pressure; Female; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; | 2014 |
Elevated serum vascular cell adhesion molecule-1 is associated with septic encephalopathy in adult community-onset severe sepsis patients.
Topics: Aged; Female; Hospital Mortality; Humans; Intercellular Adhesion Molecule-1; Lactic Acid; Male; Midd | 2014 |
Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure.
Topics: Animals; Arterial Pressure; Biomarkers; Blood Gas Analysis; Blood Glucose; Bradycardia; Circadian Rh | 2014 |
Association between hemodynamic presentation and outcome in sepsis patients.
Topics: Aged; Biomarkers; Blood Pressure; Chi-Square Distribution; Disease Progression; Emergency Service, H | 2014 |
[Serum lactate as a biomarker of severe sepsis in children with cancer, neutropenia and fever].
Topics: Biomarkers; Child; Female; Fever; Humans; Lactic Acid; Male; Neoplasms; Neutropenia; Sepsis | 2014 |
Serum adhesion molecules as outcome predictors in adult severe sepsis patients requiring mechanical ventilation in the emergency department.
Topics: Adult; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Lactic Acid; Logistic Models | 2014 |
Arterial lactate improves the prognostic performance of severity score systems in septic patients in the ED.
Topics: Aged; Aged, 80 and over; APACHE; Emergency Service, Hospital; Female; Humans; Lactic Acid; Middle Ag | 2014 |
A novel role of exogenous carbon monoxide on protecting cardiac function and improving survival against sepsis via mitochondrial energetic metabolism pathway.
Topics: Adenosine Triphosphate; Animals; Carbon Monoxide; DNA-Binding Proteins; Energy Metabolism; Gene Expr | 2014 |
ED bedside point-of-care lactate in patients with suspected sepsis is associated with reduced time to iv fluids and mortality.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Emergency Service, Hospital; Female; Fluid Therapy; H | 2014 |
Patient factors associated with identification of sepsis in the ED.
Topics: Adult; Aged; Arterial Pressure; Body Temperature; Cohort Studies; Emergency Service, Hospital; Femal | 2014 |
Diagnostic characteristics of a clinical screening tool in combination with measuring bedside lactate level in emergency department patients with suspected sepsis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Decision Support Techniques; Emergency Service, Hospital | 2014 |
Effect of rhubarb pre-treatment on intestinal microcirculation in septic rats.
Topics: Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dobutamine; Endothelial Cells; | 2014 |
Clinical predictors of adverse outcome in severe sepsis patients with lactate 2-4 mM admitted to the hospital.
Topics: Adult; Aged; Biomarkers; Comorbidity; Female; Hospitalization; Humans; Lactic Acid; Male; Middle Age | 2015 |
The prognostic value of leukocyte apoptosis in patients with severe sepsis at the emergency department.
Topics: Aged; Aged, 80 and over; Annexin A5; Apoptosis; Apoptosis Regulatory Proteins; Bacterial Infections; | 2015 |
Serum levels of caspase-cleaved cytokeratin-18 and mortality are associated in severe septic patients: pilot study.
Topics: Adult; Aged; APACHE; Biomarkers; Caspases; Female; Humans; Intensive Care Units; Interleukin-10; Int | 2014 |
Hyperlactatemia is an independent predictor of mortality and denotes distinct subtypes of severe sepsis and septic shock.
Topics: Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Hyperlactatemia; Lactic Acid; Logistic Mode | 2015 |
Lactic acid measurement to identify risk of morbidity from sepsis in pregnancy.
Topics: Adult; Female; Humans; Intensive Care Units; Lactic Acid; Length of Stay; Linear Models; Morbidity; | 2015 |
Correlation of lactate/albumin ratio level to organ failure and mortality in severe sepsis and septic shock.
Topics: Adult; Aged; APACHE; Female; Humans; Intensive Care Units; Lactic Acid; Logistic Models; Male; Middl | 2015 |
Lactate in sepsis.
Topics: Aged; Fluid Therapy; Humans; Hyperlactatemia; Lactic Acid; Male; Sepsis; Water-Electrolyte Balance | 2015 |
Disease heterogeneity and risk stratification in sepsis-related occult hypoperfusion: A retrospective cohort study.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Emergency Service, Hospital; Female; Fluid Therapy; | 2015 |
Clinical significance of circulating endothelial cells in patients with severe sepsis or septic shock.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cell Count; Endothelial Cells; Female; Flow Cytometry; H | 2015 |
Prospective evaluation of regional oxygen saturation to estimate central venous saturation in sepsis.
Topics: Aged; Area Under Curve; Blood Gas Analysis; Critical Care; Female; Hemodynamics; Humans; Intensive C | 2015 |
Serum melatonin levels are associated with mortality in severe septic patients.
Topics: Aged; Biomarkers; Female; Humans; Intensive Care Units; Interleukin-6; Lactic Acid; Logistic Models; | 2015 |
[Efficacies of continuous high volume hemofiltration in severe sepsis patients with multiple organ dysfunction syndrome].
Topics: Heart Rate; Hemodynamics; Hemofiltration; Humans; Lactic Acid; Multiple Organ Failure; Renal Dialysi | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Lactate Testing in Suspected Sepsis: Trends and Predictors of Failure to Measure Levels.
Topics: Aged; Anti-Bacterial Agents; Female; Hospital Mortality; Humans; Lactic Acid; Male; Middle Aged; Mul | 2015 |
Association between serum substance P levels and mortality in patients with severe sepsis.
Topics: Aged; Biomarkers; Critical Care; Female; Humans; Intensive Care Units; Kaplan-Meier Estimate; Lactic | 2015 |
[Analysis of the risk factors of acute respiratory distress syndrome of Berlin new definition in patients with sepsis in emergency department].
Topics: Berlin; Emergency Service, Hospital; Humans; Incidence; Lactic Acid; Lung Injury; Prognosis; Respira | 2015 |
A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock.
Topics: Adult; Aged; Biomarkers; Decision Support Techniques; Female; Health Status; Health Status Indicator | 2015 |
A Survey of the First-Hour Basic Care Tasks of Severe Sepsis and Septic Shock in Pediatric Patients and an Evaluation of Medical Simulation on Improving the Compliance of the Tasks.
Topics: Child; Child, Preschool; Emergency Medicine; Emergency Service, Hospital; Female; Fluid Therapy; Gui | 2016 |
Does every emergency department patient need a blood lactate?
Topics: Emergency Service, Hospital; Humans; Lactic Acid; Predictive Value of Tests; Prognosis; Sepsis | 2015 |
Association of left ventricular longitudinal strain with central venous oxygen saturation and serum lactate in patients with early severe sepsis and septic shock.
Topics: Adult; Aged; Blood Pressure; Echocardiography; Female; Humans; Lactic Acid; Male; Middle Aged; Oxyge | 2015 |
Shenfu injection alleviates intestine epithelial damage in septic rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Disease Models, Animal; Dose-Response Relationship, Drug | 2015 |
The Cold-Inducible RNA-Binding Protein (CIRP) Level in Peripheral Blood Predicts Sepsis Outcome.
Topics: Adult; Aged; Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; Creatinine; Female; Humans; La | 2015 |
Sepsis-associated pulmonary complications in emergency department patients monitored with serial lactate: An observational cohort study.
Topics: Adult; Aged; Cohort Studies; Emergency Medicine; Emergency Service, Hospital; Female; Humans; Incide | 2015 |
The accuracy and timeliness of a Point Of Care lactate measurement in patients with Sepsis.
Topics: Biomarkers; Blood Gas Analysis; Humans; Lactic Acid; Point-of-Care Systems; Prospective Studies; Sco | 2015 |
Long-Term β-Blocker Therapy Decreases Blood Lactate Concentration in Severely Septic Patients.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Biomarkers; Emergency Service, Hospital; Femal | 2015 |
Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients.
Topics: Aged; Cohort Studies; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Hyperlact | 2016 |
β-Blockers and Lactate in Sepsis: Same Canary But Different Mine.
Topics: Adrenergic beta-Antagonists; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Sepsis | 2015 |
"Lactate Shift," Rather Than "Lactate Clearance," for Serial Blood Lactate Monitoring?
Topics: Critical Illness; Female; Humans; Lactic Acid; Male; Sepsis; Shock, Septic | 2015 |
The author replies.
Topics: Critical Illness; Female; Humans; Lactic Acid; Male; Sepsis; Shock, Septic | 2015 |
Acute Care Diagnostics Collaboration: Assessment of a Bayesian clinical decision model integrating the Prehospital Sepsis Score and point-of-care lactate.
Topics: Bayes Theorem; Decision Support Techniques; Emergency Medical Services; Female; Hospital Mortality; | 2016 |
Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department.
Topics: Academic Medical Centers; Adult; Age Factors; Aged; Aged, 80 and over; Blood Coagulation Disorders; | 2016 |
Activation of α2 adrenoceptor attenuates lipopolysaccharide-induced hepatic injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Alanine Transaminase; | 2015 |
Comprehensive Interpretation of Central Venous Oxygen Saturation and Blood Lactate Levels During Resuscitation of Patients With Severe Sepsis and Septic Shock in the Emergency Department.
Topics: Aged; Biomarkers; Comorbidity; Emergency Service, Hospital; Female; Humans; Kaplan-Meier Estimate; L | 2016 |
Multicenter Implementation of a Treatment Bundle for Patients with Sepsis and Intermediate Lactate Values.
Topics: Aged; Anti-Bacterial Agents; Drug Administration Schedule; Emergency Medical Services; Emergency Ser | 2016 |
Lactate Clearance and Normalization and Prolonged Organ Dysfunction in Pediatric Sepsis.
Topics: Biomarkers; Child; Cohort Studies; Emergency Service, Hospital; Humans; Hypotension; Lactic Acid; Mu | 2016 |
Cytochrome C in Patients with Septic Shock.
Topics: Aged; Aged, 80 and over; Cytochromes c; Cytokines; Female; Humans; Interleukin-2; Lactic Acid; Male; | 2016 |
Time- and dose-dependent severity of lung injury in a rat model of sepsis.
Topics: Alanine Transaminase; Animals; Arteries; Aspartate Aminotransferases; Blood Gas Analysis; Blood Urea | 2015 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Lactate and combined parameters for triaging sepsis patients into intensive care facilities.
Topics: Aged; Biomarkers; Cohort Studies; Critical Care; Decision Support Techniques; Female; Humans; Intens | 2016 |
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.
Topics: Adenosine Triphosphate; Adult; Animals; Antifungal Agents; Aspergillosis; Candidiasis, Invasive; Cyt | 2016 |
The association between lactate, mean arterial pressure, central venous oxygen saturation and peripheral temperature and mortality in severe sepsis: a retrospective cohort analysis.
Topics: Aged; Arterial Pressure; Body Temperature; Central Venous Catheters; Cohort Studies; Female; Humans; | 2016 |
An acid-base disorders analysis with the use of the Stewart approach in patients with sepsis treated in an intensive care unit.
Topics: Acid-Base Imbalance; Acidosis; Adult; Aged; Algorithms; Alkalosis; Blood Gas Analysis; Critical Care | 2016 |
Prognostic Value of Lactate and Central Venous Oxygen Saturation after Early Resuscitation in Sepsis Patients.
Topics: Aged; Female; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Prognosis; Pulmonary Gas Exchange; Res | 2016 |
β-Blockade and Septic Shock Phenotype.
Topics: Adrenergic beta-Antagonists; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Sepsis | 2016 |
The authors reply.
Topics: Adrenergic beta-Antagonists; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Sepsis | 2016 |
[Value of blood lactic acid in evaluating disease severity and prognosis in children with sepsis].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Lactic Acid; Male; Prognosis; Sepsis; S | 2016 |
Blood Lactate Levels Cutoff and Mortality Prediction in Sepsis-Time for a Reappraisal? a Retrospective Cohort Study.
Topics: Aged; Aged, 80 and over; Critical Illness; Humans; Intensive Care Units; Lactic Acid; Middle Aged; P | 2016 |
A Rare Case of Caffeine Storm due to Excessive Coca-Cola Consumption.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Diabetic Ketoacidosis; Diagnosis, Differential; | 2016 |
The Correlation Between Arterial Lactate and Venous Lactate in Patients With Sepsis and Septic Shock.
Topics: Aged; Aged, 80 and over; Arteries; Blood Specimen Collection; Cross-Sectional Studies; Female; Hospi | 2018 |
Cost-effectiveness analysis of early point-of-care lactate testing in the emergency department.
Topics: Adult; Aged; Aged, 80 and over; Cost-Benefit Analysis; Costs and Cost Analysis; Emergency Service, H | 2016 |
[Venous-to-arterial carbon dioxide difference to arteriovenous oxygen content difference ratio combined with lactate to predict prognosis of patients with septic shock].
Topics: Carbon Dioxide; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Oxygen Consump | 2016 |
Prognostic value of neglected biomarker in sepsis patients with the old and new criteria: predictive role of lactate dehydrogenase.
Topics: Aged; Aged, 80 and over; Biomarkers; Clinical Enzyme Tests; Female; Heart Rate; Hospitalization; Hum | 2016 |
Impact of clinical context on acute kidney injury biomarker performances: differences between neutrophil gelatinase-associated lipocalin and L-type fatty acid-binding protein.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Biomarkers; C-Reactive Protein; Critical Illness; Fatty | 2016 |
Prognostic value of the reactive oxygen species in severe sepsis and septic shock patients: a pilot study.
Topics: Aged; Aged, 80 and over; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; Male; | 2016 |
Early Recognition and Treatment of Sepsis After the Addition of Lactate to the Laboratory's Critical Result Call List.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; APACHE; Cohort Studies; Early Diagnosis; Early Medic | 2018 |
Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study.
Topics: Acidosis, Lactic; Adult; Aged; Alcoholism; Critical Care; Critical Illness; Female; Hospital Mortali | 2016 |
Lactate clearance is associated with mortality in septic patients with acute kidney injury requiring continuous renal replacement therapy: A cohort study.
Topics: Acute Kidney Injury; Aged; Biomarkers; Brazil; Critical Illness; Female; Follow-Up Studies; Humans; | 2016 |
Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the FINNAKI Study.
Topics: Aged; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Prospective Studies; Sepsis; Sho | 2017 |
Absolute lactate value vs relative reduction as a predictor of mortality in severe sepsis and septic shock.
Topics: Aged; Aged, 80 and over; Biomarkers; Critical Care; Female; Hospital Mortality; Humans; Lactic Acid; | 2017 |
The plasma levels of CST and BCKDK in patients with sepsis.
Topics: Adult; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Neuropeptides; Protein Kinases; S | 2016 |
Impact of Metformin Use on Lactate Kinetics in Patients with Severe Sepsis and Septic Shock.
Topics: Aged; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Lactic Acid; Male; Metformin; | 2017 |
Combining quick Sequential Organ Failure Assessment with plasma lactate concentration is comparable to standard Sequential Organ Failure Assessment score in predicting mortality of patients with and without suspected infection.
Topics: Adult; APACHE; Area Under Curve; Biomarkers; Critical Care; Critical Illness; Female; Hospital Morta | 2017 |
Development and validation of a parsimonious and pragmatic CHARM score to predict mortality in patients with suspected sepsis.
Topics: Aged; Aged, 80 and over; Anemia; Biomarkers; C-Reactive Protein; Calcitonin; Chills; Cohort Studies; | 2017 |
Analytical performance of three whole blood point-of-care lactate devices compared to plasma lactate comparison methods and a flow-injection mass spectrometry method.
Topics: Blood Chemical Analysis; Humans; Lactic Acid; Point-of-Care Systems; Reference Standards; Sepsis | 2017 |
Agreement between arterial and venous lactate in emergency department patients: a prospective study of 157 consecutive patients.
Topics: Arteries; Biomarkers; Emergency Service, Hospital; Female; Humans; Hydrogen-Ion Concentration; Lacti | 2018 |
Lactate - Arterial and Venous Agreement in Sepsis: a prospective observational study.
Topics: Arteries; Biomarkers; Emergency Service, Hospital; Female; Humans; Lactic Acid; Male; Middle Aged; P | 2018 |
Improving multidisciplinary severe sepsis management using the Sepsis Six .
Topics: Disease Management; England; Humans; Lactic Acid; Length of Stay; Medical Audit; National Health Pro | 2016 |
Septic Ketoacidosis-A Potentially Lethal Entity with Renal Tubular Epithelial Vacuolization.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Epithelial Cells; Fatal Outcome; Female; Humans; Ketones; Ketosi | 2017 |
Reasons for death in patients with sepsis and septic shock.
Topics: Aged; Aged, 80 and over; Cause of Death; Cohort Studies; Consensus; Death, Sudden, Cardiac; Female; | 2017 |
Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children.
Topics: Child; Cohort Studies; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Lactic Acid; | 2017 |
Evaluation of the Association of Early Elevated Lactate With Outcomes in Children With Severe Sepsis or Septic Shock.
Topics: Biomarkers; Child, Preschool; Female; Hospital Mortality; Hospitals, Pediatric; Humans; Infant; Inte | 2019 |
Early sepsis bundle compliance for non-hypotensive patients with intermediate versus severe hyperlactemia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Databases, Factual; Female; Hospital Mortality; Huma | 2017 |
Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department.
Topics: Adult; Aged; Aged, 80 and over; Classification; Connecticut; Cross-Sectional Studies; Emergency Serv | 2018 |
Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department.
Topics: Aged; Aged, 80 and over; Comorbidity; Diabetes Mellitus; Emergency Service, Hospital; Female; Hospit | 2017 |
Cell Free DNA and Procalcitonin as Early Markers of Complications in ICU Patients with Multiple Trauma and Major Surgery.
Topics: Adult; Area Under Curve; Biomarkers; C-Reactive Protein; Calcitonin; Cell-Free Nucleic Acids; DNA; E | 2016 |
Presentation, management, and outcomes of sepsis in adults and children admitted to a rural Ugandan hospital: A prospective observational cohort study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Blood Glucose; Child; Child, Preschool; Cohort Studies; Fe | 2017 |
Serum Lactate Predicts Adverse Outcomes in Emergency Department Patients With and Without Infection.
Topics: Aged; Biomarkers; Critical Illness; Decision Support Techniques; Emergency Service, Hospital; Female | 2017 |
Is lactate clearance a good mortality predictor in sepsis?
Topics: Humans; Lactic Acid; Sepsis | 2017 |
Higher serum caspase-cleaved cytokeratin-18 levels during the first week of sepsis diagnosis in non-survivor patients.
Topics: Adult; Aged; Area Under Curve; Caspases; Female; Humans; Interleukin-10; Kaplan-Meier Estimate; Kera | 2017 |
Point-of-care testing at triage decreases time to lactate level in septic patients.
Topics: Adult; Aged; Clinical Chemistry Tests; Emergency Service, Hospital; Female; Humans; Lactic Acid; Mal | 2010 |
Anion gap as a screening tool for elevated lactate in patients with an increased risk of developing sepsis in the Emergency Department.
Topics: Acid-Base Equilibrium; Diagnosis, Differential; Emergency Medical Services; Humans; Lactic Acid; Mas | 2009 |
Lactic acidosis not hyperlactatemia as a predictor of in hospital mortality in septic emergency patients.
Topics: Acidosis, Lactic; Emergency Service, Hospital; Epidemiologic Methods; Female; Hospital Mortality; Hu | 2008 |
Early serum procalcitonin, interleukin-6, and 24-hour lactate clearance: useful indicators of septic infections in severely traumatized patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin G | 2009 |
Prognostic value of blood lactate levels: does the clinical diagnosis at admission matter?
Topics: Aged; APACHE; Critical Illness; Female; Hemodynamics; Hospital Mortality; Humans; Intensive Care Uni | 2009 |
Prediction of mortality in adult emergency department patients with sepsis.
Topics: Aged; Biomarkers; Emergency Service, Hospital; England; Epidemiologic Methods; Female; Humans; Lacti | 2009 |
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.
Topics: Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Multicenter S | 2009 |
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.
Topics: Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Multicenter S | 2009 |
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.
Topics: Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Multicenter S | 2009 |
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.
Topics: Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Multicenter S | 2009 |
Sepsis: a need for prehospital intervention?
Topics: Anti-Bacterial Agents; Communication; Critical Illness; Emergency Medical Services; Emergency Treatm | 2009 |
[Effects of ethyl pyruvate on injuries of sepsis in mice].
Topics: Alkaline Phosphatase; Animals; Disease Models, Animal; Intestines; Lactic Acid; Lung; Male; Mice; Py | 2009 |
The feasibility and accuracy of point-of-care lactate measurement in emergency department patients with suspected infection.
Topics: Adult; Aged; Area Under Curve; Emergency Service, Hospital; Feasibility Studies; Female; Humans; Lac | 2010 |
Hydroxyethyl starch 130/0.4 inhibits production of plasma proinflammatory cytokines and attenuates nuclear factor-kappaB activation and Toll-like receptors expression in monocytes during sepsis.
Topics: Animals; Cecum; Cytokines; Hemodynamics; Hydroxyethyl Starch Derivatives; Interleukin-6; Lactic Acid | 2010 |
Effect of beta blockers on sepsis outcome.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; APACHE; Female; Humans; Lactic Acid; Ma | 2009 |
Lactate: finally ready for prime time?
Topics: Acidosis, Lactic; Critical Care; Decision Support Techniques; Humans; Lactic Acid; Monitoring, Physi | 2009 |
Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats.
Topics: Adrenomedullin; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cecum; Complement Factor | 2010 |
Out-of-hospital characteristics and care of patients with severe sepsis: a cohort study.
Topics: Academic Medical Centers; Aged; Emergency Medical Services; Female; Humans; Lactic Acid; Male; Middl | 2010 |
[Therapy concepts for septic diseases].
Topics: Central Venous Pressure; Combined Modality Therapy; Critical Care; Diagnosis, Differential; Humans; | 2010 |
Skin collagen synthesis is depressed in patients with severe sepsis.
Topics: Aged; Collagen; Collagen Type I; Collagen Type III; Critical Care; Female; Humans; Lactic Acid; Male | 2010 |
Lactate clearance and central venous oxygen saturation in early sepsis.
Topics: Cardiotonic Agents; Dobutamine; Humans; Lactic Acid; Monitoring, Physiologic; Oxygen; Reproducibilit | 2010 |
Increased muscle-to-serum lactate gradient predicts progression towards septic shock in septic patients.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Disease Progres | 2010 |
[Early high-volume hemofiltration treatment in severe sepsis].
Topics: Adult; APACHE; C-Reactive Protein; Female; Hemofiltration; Humans; Interleukin-10; Interleukin-6; La | 2010 |
Detecting and treating sepsis in the emergency department.
Topics: Anti-Bacterial Agents; Disease Progression; Early Diagnosis; Emergency Nursing; Emergency Service, H | 2011 |
Comparison of lactate values obtained from different sites and their clinical significance in patients with severe sepsis.
Topics: Adult; Aged; Arteries; Case-Control Studies; Cross-Sectional Studies; Female; Humans; Lactic Acid; M | 2011 |
The value of the Mortality in Emergency Department Sepsis (MEDS) score, C reactive protein and lactate in predicting 28-day mortality of sepsis in a Dutch emergency department.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Biomarkers; C-Reactive Protein; Cohort Studies; Fe | 2012 |
A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis.
Topics: Animals; Blood Glucose; Crystalloid Solutions; Escherichia coli Infections; Fluid Therapy; Glycerol; | 2011 |
Correlation of interleukin-6, serum lactate, and C-reactive protein to inflammation, complication, and outcome during the surgical course of patients with acute abdomen.
Topics: Abdomen, Acute; Adolescent; Adult; Aged; Aged, 80 and over; C-Reactive Protein; Case-Control Studies | 2011 |
Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item: a multi-national evaluation.
Topics: Aged; Asia; Female; Guideline Adherence; Humans; Lactic Acid; Male; Metabolic Clearance Rate; Middle | 2011 |
The role of lactate clearance in the resuscitation bundle.
Topics: Female; Guideline Adherence; Humans; Lactic Acid; Male; Resuscitation; Sepsis | 2011 |
Point: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? Yes.
Topics: Central Venous Pressure; Critical Illness; Emergency Service, Hospital; Female; Humans; Lactic Acid; | 2011 |
Counterpoint: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? No.
Topics: Female; Humans; Lactic Acid; Male; Oxygen; Resuscitation; Sepsis | 2011 |
Implementing Surviving Sepsis guidelines in a district general hospital.
Topics: Anti-Bacterial Agents; Guideline Adherence; Hematologic Tests; Hospital Mortality; Hospitals, Distri | 2011 |
Determination of lactate value.
Topics: Female; Humans; Lactic Acid; Male; Sepsis | 2012 |
Sepsis, lactate, and oxygen supply dependence.
Topics: Female; Humans; Lactic Acid; Male; Oxygen; Resuscitation; Sepsis | 2012 |
Serum lactate is a useful predictor of death in severe sepsis in patients with pemphigus vulgaris.
Topics: Adult; Bacteremia; Comorbidity; Female; Humans; Lactic Acid; Logistic Models; Male; Pemphigus; Progn | 2012 |
Predicting factors associated with clinical deterioration of sepsis patients with intermediate levels of serum lactate.
Topics: Aged; Disease Progression; Female; Humans; Kaplan-Meier Estimate; Lactic Acid; Male; Middle Aged; Re | 2012 |
Red blood cell transfusion affects microdialysis-assessed interstitial lactate/pyruvate ratio in critically ill patients with late sepsis.
Topics: Adipose Tissue; Aged; Blood Specimen Collection; Erythrocyte Transfusion; Extracellular Fluid; Femal | 2012 |
Glutamine treatment decreases plasma and lymph cytotoxicity during sepsis in rats.
Topics: Animals; Blood; Blotting, Western; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; Enzyme- | 2012 |
Identification of a lactate-quinone oxidoreductase in Staphylococcus aureus that is essential for virulence.
Topics: Animals; Bacterial Proteins; Disease Models, Animal; Genes, Bacterial; Host-Pathogen Interactions; H | 2011 |
The dynamics of angiogenic factors and their soluble receptors in relation to organ dysfunction in disseminated intravascular coagulation associated with sepsis.
Topics: Angiogenesis Inducing Agents; Angiopoietin-1; Angiopoietin-2; Blood Platelets; Cell Hypoxia; Dissemi | 2013 |
Expression of interleukin-1β, interleukin-8, and interferon-γ in blood samples obtained from healthy and sick neonatal foals.
Topics: Animals; Animals, Newborn; Asphyxia; Fibrinogen; Horse Diseases; Horses; Interferon-gamma; Interleuk | 2012 |
The use of laboratory and physiological parameters in predicting mortality in sepsis induced hypotension and septic shock patients attending the emergency department.
Topics: Adolescent; Adult; Biomarkers; Emergency Service, Hospital; Humans; Hypotension; Kaplan-Meier Estima | 2012 |
Interrelationship between blood and tissue lactate in a general intensive care unit: a subcutaneous adipose tissue microdialysis study on 162 critically ill patients.
Topics: Adipose Tissue; Aged; Extracellular Fluid; Female; Health Status Indicators; Humans; Intensive Care | 2012 |
A syndrome of severe hypoglycemia and acidosis in young immunosuppressed diabetic monkeys and pigs-association with sepsis.
Topics: Acidosis; Animals; Bacteria; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; | 2012 |
Early detection and treatment of patients with severe sepsis by prehospital personnel.
Topics: Blood Pressure; Case-Control Studies; Clinical Protocols; Crystalloid Solutions; Early Diagnosis; Em | 2013 |
Melatonin improved rat cardiac mitochondria and survival rate in septic heart injury.
Topics: Animals; Electron Transport Complex IV; Heart; Kaplan-Meier Estimate; Lactic Acid; Male; Melatonin; | 2013 |
Early immunoneutralization of calcitonin precursors attenuates the adverse physiologic response to sepsis in pigs.
Topics: Animals; Antibodies; Calcitonin; Calcitonin Gene-Related Peptide; Cardiac Output; Escherichia coli I | 2002 |
Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1.
Topics: Adrenomedullin; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiac Output; Carrier | 2002 |
Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin-binding protein-1 in sepsis: down-regulation of proinflammatory cytokines.
Topics: Adrenomedullin; Analysis of Variance; Animals; Cardiac Output; Complement Factor H; Cytokines; Down- | 2002 |
Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock.
Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cyclic AMP; Dexamethasone; Dose-Response Relatio | 2003 |
Low exogenous lactate clearance as an early predictor of mortality in normolactatemic critically ill septic patients.
Topics: Age Distribution; Age Factors; Aged; Blood Gas Analysis; Comorbidity; Critical Illness; Female; Hosp | 2003 |
Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients.
Topics: Aged; APACHE; Biomarkers; Blood Gas Analysis; Capnography; Carbon Dioxide; Catheterization, Swan-Gan | 2003 |
The hepatosplanchnic area is not a common source of lactate production.
Topics: Acidosis, Lactic; Acute Disease; Humans; Lactic Acid; Liver; Mesentery; Sepsis; Time Factors | 2003 |
Proinflammatory cytokines increase the rate of glycolysis and adenosine-5'-triphosphate turnover in cultured rat enterocytes.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Cytokines; Enterocytes; Glucose; Glycol | 2003 |
Increased tissue oxygen extraction and acidosis with progressive severity of sepsis.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood Pressure; Carbon Dioxide; Disease Progression; Heart | 2003 |
Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia.
Topics: Animals; Blood Pressure; Carbon Dioxide; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Lipopolysa | 2003 |
Sepsis-induced failure of hepatic energy metabolism.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bacteremia; Blood F | 2003 |
[An early comprehensive prevention and treatment of sepsis in severely burned patients with delayed fluid resuscitation].
Topics: Adult; Anti-Bacterial Agents; Burns; Epidermal Growth Factor; Female; Fibroblast Growth Factor 2; Fi | 2004 |
[Change in intestinal function in sepsis in rat].
Topics: Amine Oxidase (Copper-Containing); Animals; Disease Models, Animal; Intestines; Ischemia; Lactic Aci | 2004 |
Effects of dichloroacetate and ubiquinone infusions on glycolysis activity and thermal sensitivity during sepsis.
Topics: Animals; Body Temperature Regulation; Coenzymes; Dichloroacetic Acid; Electron Transport Complex III | 2004 |
Lac-time?
Topics: Biomarkers; Emergency Medical Services; Humans; Lactic Acid; Outcome and Process Assessment, Health | 2004 |
Arterial lactate concentration, hospital survival, sepsis and SIRS in critically ill neonatal foals.
Topics: Acid-Base Equilibrium; Animals; Animals, Newborn; Blood Gas Analysis; Critical Illness; Horse Diseas | 2005 |
Insulin prevents liver damage and preserves liver function in lipopolysaccharide-induced endotoxemic rats.
Topics: Acute-Phase Proteins; Adenosine Triphosphate; Animals; Apoptosis; Blood Glucose; Caspase 3; Caspase | 2005 |
Lactate concentration gradient from right atrium to pulmonary artery: a commentary.
Topics: Biomarkers; Coronary Circulation; Heart Atria; Humans; Lactic Acid; Myocardial Ischemia; Oxygen; Pul | 2005 |
Lactate and glucose metabolism in severe sepsis and cardiogenic shock.
Topics: Adult; Case-Control Studies; Glucose; Humans; Lactic Acid; Oxidation-Reduction; Prospective Studies; | 2005 |
Lactic acidosis in sepsis: another commentary.
Topics: Acidosis, Lactic; Glucose; Humans; Lactic Acid; Pyruvic Acid; Sepsis | 2005 |
Early veno-venous haemodiafiltration for sepsis-related multiple organ failure.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Electrolytes; Female; Hemofiltration; Humans; Lactic Acid; | 2005 |
[Clinical study on bacterial translocation in severe multiple trauma patients].
Topics: Adolescent; Adult; Bacterial Translocation; DNA, Bacterial; Female; Humans; Intestines; Lactic Acid; | 2006 |
Evolutive standard base excess and serum lactate level in severe sepsis and septic shock patients resuscitated with early goal-directed therapy: still outcome markers?
Topics: Acid-Base Equilibrium; Adult; Aged; APACHE; Biomarkers; Clinical Protocols; Female; Humans; Lactic A | 2006 |
Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Biopsy; Citrate (si)-Synthase; Critical Illn | 2006 |
Failure to implement evidence-based clinical guidelines for sepsis at the ED.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; APACHE; Clinical Protocols; Critical Care; Dr | 2006 |
Increased colorectal permeability in patients with severe sepsis and septic shock.
Topics: Adult; Aged; Analysis of Variance; Case-Control Studies; Female; Humans; Intestinal Mucosa; Intestin | 2006 |
Downregulation of hepatic cytochrome P-450 isoforms and PPAR-gamma: their role in hepatic injury and proinflammatory responses in a double-hit model of hemorrhage and sepsis.
Topics: Alanine Transaminase; Animals; Aryl Hydrocarbon Hydroxylases; Aspartate Aminotransferases; Cytochrom | 2007 |
Luminal concentrations of L- and D-lactate in the rectum may relate to severity of disease and outcome in septic patients.
Topics: Adult; Aged; Case-Control Studies; Female; Humans; Lactic Acid; Male; Middle Aged; Prognosis; Prospe | 2006 |
Comparison of three different methods of evaluation of metabolic acid-base disorders.
Topics: Acid-Base Imbalance; Aged; Albumins; Anions; Area Under Curve; Bicarbonates; Female; Humans; Hydroge | 2007 |
Dynamic near-infrared spectroscopy measurements in patients with severe sepsis.
Topics: Aged; Blood Pressure; Female; Hemoglobins; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Sepsis; S | 2007 |
Dynamic near-infrared spectroscopy measurements in patients with severe sepsis.
Topics: Aged; Blood Pressure; Female; Hemoglobins; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Sepsis; S | 2007 |
Dynamic near-infrared spectroscopy measurements in patients with severe sepsis.
Topics: Aged; Blood Pressure; Female; Hemoglobins; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Sepsis; S | 2007 |
Dynamic near-infrared spectroscopy measurements in patients with severe sepsis.
Topics: Aged; Blood Pressure; Female; Hemoglobins; Humans; Lactic Acid; Male; Middle Aged; Oxygen; Sepsis; S | 2007 |
Serum lactate as a predictor of mortality in patients with infection.
Topics: Academic Medical Centers; Adult; Aged; Bayes Theorem; Female; Humans; Lactic Acid; Male; Middle Aged | 2007 |
Effects of granulocyte-colony stimulating factor on the polymorphonuclear leukocyte activity and the course of sepsis in rats with experimental peritonitis.
Topics: Animals; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Lactic Acid; Male; Neutrophils; Peri | 2007 |
Management of severe sepsis and septic shock in the emergency department: a survey of current practice in emergency departments in England.
Topics: Anti-Bacterial Agents; Clinical Protocols; Emergency Medicine; Emergency Service, Hospital; England; | 2007 |
Caecal ligation and puncture in the rat mimics the pathophysiological changes in human sepsis and causes multi-organ dysfunction.
Topics: Animals; Blood Glucose; Body Temperature; Body Weight; Cecum; Disease Models, Animal; Eating; Humans | 2007 |
The control of hepatic glycogen metabolism in an in vitro model of sepsis.
Topics: Adenylate Kinase; Animals; Cytokines; Disease Models, Animal; Glucose; Glucose-6-Phosphate; Glycogen | 2008 |
Na+-dependent neutral amino acid transporter ASCT2 is downregulated in seriously traumatized human intestinal epithelial cells.
Topics: Alanine; Amino Acid Transport System ASC; Amino Acids; Blotting, Western; Caco-2 Cells; Cell Hypoxia | 2008 |
Temporal changes in the involvement of pyruvate dehydrogenase complex in muscle lactate accumulation during lipopolysaccharide infusion in rats.
Topics: Animals; Infusions, Parenteral; Interleukin-6; Lactic Acid; Lipopolysaccharides; Male; Muscle, Skele | 2008 |
Increased aerobic glycolysis through beta2 stimulation is a common mechanism involved in lactate formation during shock states.
Topics: Animals; Epinephrine; Glycolysis; Hypoxia; Lactic Acid; Male; Oxygen; Rats; Rats, Wistar; Receptors, | 2008 |
Protective effects and role of endotoxin in experimental septicemia.
Topics: Animals; Bacteriological Techniques; Blood Glucose; Cecum; Disease Models, Animal; Endotoxins; Esche | 1984 |
Regulation of glucose production from lactate in experimental sepsis.
Topics: Adenosine Triphosphate; Animals; Gluconeogenesis; Glucose; In Vitro Techniques; Lactates; Lactic Aci | 1983 |
Experimental pneumococcal meningitis: role of leukocytes in pathogenesis.
Topics: Animals; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Glucose; Kinetics; Lactates; Lactic Acid | 1983 |
Combined measurements of blood lactate concentrations and gastric intramucosal pH in patients with severe sepsis.
Topics: Acute Disease; Analysis of Variance; APACHE; Critical Care; Gastric Acidity Determination; Gastric M | 1995 |
Effects of sepsis on recovery of the heart from 50 min ischemia.
Topics: Adenosine Triphosphate; Alcoholism; Animals; Catalase; Escherichia coli; Lactates; Lactic Acid; Male | 1994 |
Changes in regulators of circulation in patients undergoing continuous pump-driven veno-venous hemofiltration.
Topics: Acute Kidney Injury; Atrial Natriuretic Factor; Blood Circulation; Blood Pressure; Creatinine; Dopam | 1994 |
Glucose, lactate, insulin, and somatostatin responses to endotoxin in developing rats.
Topics: Age Factors; Animals; Bacterial Toxins; Blood Glucose; Disease Models, Animal; Endotoxins; Female; H | 1994 |
Hormone effects on hepatic substrate preference in sepsis.
Topics: Alanine; Animals; Energy Metabolism; Gluconeogenesis; Hormones; Lactates; Lactic Acid; Liver; Male; | 1994 |
Pentoxifylline improves survival and reduces tumor necrosis factor, interleukin-6, and endothelin-1 in fulminant intra-abdominal sepsis in rats.
Topics: Abdomen; Animals; Cecal Diseases; Disease Models, Animal; Endothelins; Endotoxins; Interleukin-6; In | 1995 |
Oxygen transport-dependent splanchnic metabolism in the sepsis syndrome.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Output; Humans; Lactates; Lactic Acid; Male; Middle Aged; Ox | 1994 |
Effect of sepsis on brain energy metabolism in normoxic and hypoxic rats.
Topics: Animals; Brain; Energy Metabolism; Female; Hypoxia; Lactates; Lactic Acid; Magnetic Resonance Spectr | 1993 |
Transvisceral lactate fluxes during early endotoxemia.
Topics: Animals; Blood Flow Velocity; Cardiac Output; Dogs; Endotoxins; Escherichia coli; Hindlimb; Intestin | 1996 |
Amrinone prevents the inhibition of muscle pyruvate dehydrogenase complex activity during sepsis.
Topics: Amrinone; Animals; Enzyme Inhibitors; Lactates; Lactic Acid; Least-Squares Analysis; Linear Models; | 1996 |
Comparison of gastric intramucosal pH measurements with oxygen supply, oxygen consumption and arterial lactate in patients with severe sepsis.
Topics: Adolescent; Adult; Aged; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Hypoxia; Lactic Acid; M | 1996 |
Pulmonary lactate release in patients with sepsis and the adult respiratory distress syndrome.
Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Output; Female; Gastric Mucosa | 1996 |
The regional production of cytokines and lactate in sepsis-related multiple organ failure.
Topics: Aged; Craniocerebral Trauma; Cytokines; Female; Humans; Interleukin-1; Interleukin-6; Lactic Acid; L | 1997 |
Small intestinal mucosal pH and lactate production during experimental ischemia-reperfusion and fecal peritonitis in pigs.
Topics: Animals; Blood Pressure; Cardiac Output; Feces; Female; Hemoglobins; Hydrogen-Ion Concentration; Int | 1997 |
Diaspirin crosslinked hemoglobin improves systemic oxygen uptake in oxygen supply-dependent septic rats.
Topics: Animals; Aspirin; Blood Gas Analysis; Blood Substitutes; Erythrocyte Transfusion; Erythrocytes; Hemo | 1997 |
Early markers of major adverse events in children after cardiac operations.
Topics: Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cohort Studies; Heart Arrest; H | 1997 |
Mild hyperlactatemia in stable septic patients is due to impaired lactate clearance rather than overproduction.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Lactic Acid; Male; Metabolic Clearance Rate; Middle | 1998 |
Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients?
Topics: Arteries; Critical Illness; Dobutamine; Dose-Response Relationship, Drug; Female; Hepatic Veins; Hum | 1998 |
Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis.
Topics: Animals; Antibodies, Monoclonal; Bacteremia; Blood Pressure; Complement C5a; Disease Models, Animal; | 1998 |
Interpretation of blood lactate concentrations in patients with sepsis.
Topics: Biomarkers; Humans; Lactic Acid; Sepsis | 1998 |
Carnitine deprivation adversely affects cardiovascular response to bacterial endotoxin (LPS) in the anesthetized neonatal pig.
Topics: Anesthesia; Animals; Animals, Newborn; Blood Glucose; Blood Pressure; Cardiac Output; Cardiovascular | 1998 |
Selective in vivo inhibition of inducible nitric oxide synthase in a rat model of sepsis.
Topics: Animals; Aorta, Thoracic; Blood Gas Analysis; Blood Pressure; Blood Vessels; Cecum; Enzyme Inhibitor | 1999 |
Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood.
Topics: Animals; Biomarkers; Blood Platelets; Critical Illness; Erythrocytes; Female; Glycolysis; Humans; Hy | 1999 |
Does blood lactate measurement have a role in the management of the critically ill patient?
Topics: Critical Illness; Humans; Lactic Acid; Patient Care Planning; Reference Values; Regional Blood Flow; | 1999 |
Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis.
Topics: Animals; Cardiac Output; Cecum; Cell Hypoxia; Disease Models, Animal; Intestine, Small; Kidney; Lact | 1999 |
Mitochondrial redox state in the critically ill.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Biomarkers; Critical Illness; Humans; Ketone Bodi | 1999 |
Plasma alpha-glutathione S-transferase: a sensitive indicator of hepatocellular damage during polymicrobial sepsis.
Topics: Animals; Biomarkers; Clinical Enzyme Tests; Glutathione Transferase; Lactic Acid; Liver; Liver Funct | 2000 |
Nitric oxide produced via neuronal NOS may impair vasodilatation in septic rat skeletal muscle.
Topics: Acetylcholine; Animals; Arterioles; Enzyme Inhibitors; Lactic Acid; Male; Muscle, Skeletal; Necrosis | 2000 |
The effects of interleukin-10 in hemorrhagic shock.
Topics: Animals; Interleukin-1; Interleukin-10; Interleukin-6; Lactic Acid; Male; Rats; Rats, Sprague-Dawley | 2000 |
Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Calcitonin; Critical Care; Critical | 2000 |
Intramucosal pH and pCO(2) do not strictly correlate with intestinal energy metabolism in experimental peritonitis.
Topics: Adenosine Triphosphate; Anaerobiosis; Animals; Carbon Dioxide; Energy Metabolism; Female; Hematocrit | 2000 |
Taurine and pulmonary hemodynamics in sepsis.
Topics: Adolescent; Adult; Amino Acids; Atrial Function, Right; Blood Pressure; Female; Hemodynamics; Humans | 2000 |
The hepatosplanchnic area is not a common source of lactate in patients with severe sepsis.
Topics: Acidosis, Lactic; Aged; APACHE; Blood Flow Velocity; Blood Gas Analysis; Carbon Dioxide; Catecholami | 2001 |
Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients.
Topics: Algorithms; Blood Gas Analysis; Blood Pressure; Cardiac Output; Critical Care; Decision Trees; Diast | 2001 |
Carboxyhemoglobin and lactate levels do not correlate in critically ill patients.
Topics: Animals; Biomarkers; Blood Gas Analysis; Carboxyhemoglobin; Critical Illness; Disease Models, Animal | 1999 |
Sublingual capnometry and indexes of tissue perfusion in patients with circulatory failure.
Topics: APACHE; Blood Circulation; Capnography; Carbon Dioxide; Cardiac Output, Low; Gastric Mucosa; Hemodyn | 2001 |
[Impact of intracellular Na+ concentration alteration on intracellular aerobic glycolysis in skeletal muscles in sepsis].
Topics: Animals; Glycolysis; Lactic Acid; Male; Monensin; Muscle, Skeletal; Rats; Rats, Wistar; Sepsis; Sodi | 1999 |
Serial measurement of arterial lactate concentrations as a prognostic indicator in relation to the incidence of disseminated intravascular coagulation in patients with systemic inflammatory response syndrome.
Topics: Analysis of Variance; Area Under Curve; Biomarkers; Cohort Studies; Critical Illness; Disseminated I | 2001 |
Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis.
Topics: Alpha-Globulins; Analysis of Variance; Animals; Cardiac Output; Hemodynamics; Humans; Lactic Acid; M | 2002 |
Understanding sepsis: promise, caution, and accolades to a mentor's mentor.
Topics: Alpha-Globulins; Animals; Hemodynamics; Lactic Acid; Rats; Sepsis; Serine Proteinase Inhibitors; Tra | 2002 |
Role of skeletal muscle Na+-K+ ATPase activity in increased lactate production in sub-acute sepsis.
Topics: Adenosine Triphosphate; Animals; Epinephrine; Lactic Acid; Male; Muscle, Skeletal; Phosphocreatine; | 2002 |
Sepsis in the young rat: maternal milk protects during cecal ligation and puncture sepsis but not during endotoxemia.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Cecum; Diet; Endotoxins; Lactates; Lactic Acid; Lig | 1991 |
Hepatic insulin resistance during canine sepsis.
Topics: Animals; Dogs; Female; Glucose; Glucose Clamp Technique; Homeostasis; Insulin; Insulin Resistance; L | 1991 |
Maximal activity of phosphate-dependent glutaminase and glutamine metabolism in septic rats.
Topics: Alanine; Animals; Arteries; Glutaminase; Glutamine; Intestinal Mucosa; Kidney; Lactates; Lactic Acid | 1991 |
Glucoregulatory, hormonal, and metabolic responses to endotoxicosis or cecal ligation and puncture sepsis in the rat: a direct comparison.
Topics: Animals; Blood Glucose; Cecum; Disease Models, Animal; Glucagon; Insulin; Kinetics; Lactates; Lactic | 1990 |
Pharmacologic modulation of increased release of gluconeogenic precursors from extra-splanchnic organs in sepsis.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Cycloserine; Dichloroacetic Acid; Gluconeogenes | 1989 |
In vivo insulin resistance during nonlethal hypermetabolic sepsis.
Topics: Animals; Blood Glucose; Escherichia coli Infections; Fasting; Glucagon; Glucose; Insulin; Insulin Re | 1989 |
Role of extra-splanchnic organs in the metabolic response to sepsis: effect of insulin.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Glutamine; Hepatectomy; I | 1989 |
Selective removal of endotoxin from the blood by extracorporeal hemoperfusion with polymyxin B immobilized fiber.
Topics: Animals; Blood Glucose; Dogs; Endotoxins; Escherichia coli; Escherichia coli Infections; Hemoperfusi | 1988 |
Impairments in vasopressin-stimulated inositol lipid metabolism in hepatocytes of septic rats.
Topics: Animals; Blood Glucose; Kinetics; Lactates; Lactic Acid; Liver; Male; Phosphatidic Acids; Phosphatid | 1988 |
The effects of chronic bacteremia on the metabolic response to exercise in the conscious rat.
Topics: Acid-Base Equilibrium; Animals; Bacteroides fragilis; Bacteroides Infections; Blood Gas Analysis; Bl | 1988 |
Inhibition of eicosanoid production by BW755C does not attenuate sepsis-induced alterations in glucose kinetics.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Blood Glucose; Eicosanoic Aci | 1987 |
Fever is not responsible for the elevated glucose kinetics in sepsis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibito | 1987 |
Plasma catecholamines during E. coli bacteremia in conscious rats.
Topics: Animals; Blood Glucose; Blood Pressure; Consciousness; Drug Tolerance; Endotoxins; Epinephrine; Esch | 1988 |
3-O-methylglucose transport in soleus muscle of bacteremic rats.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Blood Glucose; Escherichia coli Infections; Lactat | 1987 |
Pathological supply dependence of O2 uptake during bacteremia in dogs.
Topics: Animals; Blood Pressure; Dogs; Hemodynamics; Lactates; Lactic Acid; Oxygen Consumption; Pseudomonas | 1987 |