lactic acid has been researched along with Basal Ganglia Diseases in 6 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both patients had PDH deficiency caused by a new mutation (G585C) in the PDHA1 gene, which is predicted to replace a highly conserved glycine at codon 195 by alanine." | 1.35 | Pyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia. ( Debray, FG; Gagne, R; Laframboise, R; Lambert, M; MacKay, N; Maranda, B; Mitchell, GA; Robinson, BH, 2008) |
| "We report a new case of MERRF (myoclonus epilepsy with ragged red fibers) syndrome with basal nuclei calcification on the brain CT scan, without hormonal abnormalities, with high CSF protein and hyperlactacidemia, juvenile onset and death at 18 years." | 1.27 | Mitochondrial encephalo-neuro-myopathy with myoclonus epilepsy, basal nuclei calcification and hyperlactacidemia. ( Cornelio, F; Di Donato, S; Ederli, E; Fabrizi, GM; Federico, A; Guazzi, GC; Manneschi, L, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lagrue, E | 1 |
| Abert, B | 1 |
| Nadal, L | 1 |
| Tabone, L | 1 |
| Bodard, S | 1 |
| Medja, F | 1 |
| Lombes, A | 1 |
| Chalon, S | 1 |
| Castelnau, P | 1 |
| Vokaer, M | 1 |
| Bier, JC | 1 |
| David, P | 1 |
| Grand, S | 1 |
| Supiot, F | 1 |
| Ventura, M | 1 |
| Bartholomé, EJ | 1 |
| Morava, E | 1 |
| Rodenburg, RJ | 1 |
| Hol, F | 1 |
| de Vries, M | 1 |
| Janssen, A | 1 |
| van den Heuvel, L | 1 |
| Nijtmans, L | 1 |
| Smeitink, J | 1 |
| Debray, FG | 1 |
| Lambert, M | 1 |
| Gagne, R | 1 |
| Maranda, B | 1 |
| Laframboise, R | 1 |
| MacKay, N | 1 |
| Robinson, BH | 1 |
| Mitchell, GA | 1 |
| Federico, A | 1 |
| Cornelio, F | 1 |
| Di Donato, S | 1 |
| Ederli, E | 1 |
| Fabrizi, GM | 1 |
| Manneschi, L | 1 |
| Guazzi, GC | 1 |
| Al-Mateen, M | 1 |
| Philippart, M | 1 |
| Shields, WD | 1 |
6 other studies available for lactic acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Basal Ganglia Diseases; Diseas | 2009 |
Striatal lesions: an underestimated complication of cerebral malaria?
Topics: Adult; Animals; Basal Ganglia Diseases; Corpus Striatum; Humans; Lactic Acid; Magnetic Resonance Ima | 2004 |
Clinical and biochemical characteristics in patients with a high mutant load of the mitochondrial T8993G/C mutations.
Topics: Adenosine Triphosphate; Alanine; Basal Ganglia Diseases; Child; Child, Preschool; DNA, Mitochondrial | 2006 |
Pyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia.
Topics: Ataxia; Basal Ganglia Diseases; Binding Sites; Brain Diseases, Metabolic; Child; Child, Preschool; D | 2008 |
Mitochondrial encephalo-neuro-myopathy with myoclonus epilepsy, basal nuclei calcification and hyperlactacidemia.
Topics: Adolescent; Basal Ganglia Diseases; Calcinosis; Epilepsy; Humans; Lactates; Lactic Acid; Male; Mitoc | 1988 |
Rett syndrome. A commonly overlooked progressive encephalopathy in girls.
Topics: Adolescent; Adult; Ataxia; Basal Ganglia Diseases; Brain Diseases; Child; Child, Preschool; Dementia | 1986 |