Page last updated: 2024-10-18

lactic acid and Bacterial Meningitides

lactic acid has been researched along with Bacterial Meningitides in 61 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"In patients with acute bacterial meningitis, we found variable levels of CBF and cerebrovascular CO(2) reactivity, a low a-v DO(2), low cerebral metabolic rates of oxygen and glucose, and a cerebral lactate efflux."2.70Cerebral blood flow, oxidative metabolism and cerebrovascular carbon dioxide reactivity in patients with acute bacterial meningitis. ( Holm, S; Knudsen, GM; Larsen, FS; Møller, K; Skinhøj, P; Sperling, BK; Strauss, GI; Thomsen, G, 2002)
"Bacterial meningitis is not rare in post-neurosurgical patients."2.53The diagnostic value of cerebrospinal fluid lactate for post-neurosurgical bacterial meningitis: a meta-analysis. ( Ji, N; Kang, P; Xiao, X; Zhang, L; Zhang, Y, 2016)
"Bacterial meningitis and tubercular meningitis are still neurological emergencies characterized by severe mortality and morbidity."2.48[Revival of old diagnostic markers in the cerebrospinal fluid for the detection of infectious meningitis]. ( Sakushima, K; Sasaki, H; Yabe, I, 2012)
"Making a differential diagnosis between bacterial meningitis and aseptic meningitis is a critical clinical problem."2.46Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systemic review and meta-analysis. ( Diep, DT; Hirayama, K; Huy, NT; Kikuchi, M; Thao, NT; Zamora, J, 2010)
"Group 2 included 20 patients with viral meningitis."1.91Cerebrospinal Fluid Lactate as a Differential Biomarker for Bacterial and Viral Meningitis. ( Arafa, ZAA; ElMasry, SA; Fahim, NA; Gabr, MS; Kamel, EM, 2023)
"Bacterial meningitis is a serious complication after neurosurgery and has a high mortality rate."1.91The value of elevated cerebrospinal fluid lactate concentrations in post-neurosurgical bacterial meningitis. ( Kong, Y; Peng, Y; Wang, Q; Wang, Y; Yang, Y, 2023)
"Scrub typhus is one of the most common causes of meningo-encephalitis in endemic areas of the Indian subcontinent."1.62Is cerebrospinal fluid lactate useful in differentiating scrub typhus meningitis from aseptic, bacterial and tuberculous meningitis? ( Abhilash, KPP; Arora, S; Gunasekharan, K; Hazra, D; Mitra, S; Yesudass, P, 2021)
"CSF glucose was significantly lower in bacterial meningitis cases (P<0."1.51Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis. ( Domingues, RB; Fernandes, GBP; Leite, FBVM; Senne, C, 2019)
"Aseptic meningitis is the most common form of meningitis with an annual incidence of 7."1.46Aseptic and Bacterial Meningitis: Evaluation, Treatment, and Prevention. ( Boyle, SD; Mount, HR, 2017)
"Differentiating bacterial meningitis from viral meningitis is a diagnostic challenge."1.43Cerebrospinal fluid lactate: measurement of an adult reference interval. ( Allgar, V; Holbrook, IB; Slack, SD; Turley, P, 2016)
"Patients suffering from acute bacterial meningitis (ABM) with a decreased level of consciousness have been shown to have an improved clinical outcome if treated with an intracranial pressure (ICP) guided therapy."1.43Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study. ( Bartek, J; Bellander, BM; Ghatan, PH; Glimaker, M; Thelin, EP, 2016)
"According to previous studies, cerebral ischemia was defined as lactate/pyruvate (LP) ratio > 30 with intracerebral pyruvate level < 70 µmol L(-1)."1.42Bedside evaluation of cerebral energy metabolism in severe community-acquired bacterial meningitis. ( Andersen, ÅB; Jacobsen, A; Larsen, L; Nielsen, TH; Nordström, CH; Poulsen, FR; Schalén, W; Schulz, M, 2015)
"CSF LA in the groups with viral meningitis was not different compared to groups with non-infectious CNS diseases and chronic meningitis."1.35Quantitation of cerebrospinal fluid lactic acid in infectious and non-infectious neurological diseases. ( Berto, DB; Buczenko, GM; de Almeida, SM; de Goes Fontes, K; Faria, FL; Nogueira, MB; Raboni, SM; Vidal, LR, 2009)
"Among 53 bacterial meningitis patients, Neisseria meningitides were isolated in 29 (54."1.35CSF lactate level: a useful diagnostic tool to differentiate acute bacterial and viral meningitis. ( Abdou, AS; Abro, AH; Doleh, WF; Saleh, AA; Ustadi, AM; Younis, NJ, 2009)
"In search for a supplementary marker of bacterial meningitis in cases where conventional bacteriology, cytology and chemistry are insufficiently contributive to diagnosis, we assessed the value of cerebrospinal fluid lactate levels in children with bacterial meningitis."1.30[Assay of lactic acid in the cerebrospinal fluid for the diagnosis of bacterial meningitis. Strategies for the choice of discriminatory threshold]. ( Bosson, JL; François, P; Kayemba Kay'S, S; Lafond, JL; Pavese, P, 1997)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (16.39)18.2507
2000's12 (19.67)29.6817
2010's31 (50.82)24.3611
2020's8 (13.11)2.80

Authors

AuthorsStudies
Arafa, ZAA1
Gabr, MS1
Kamel, EM1
ElMasry, SA1
Fahim, NA1
Wang, Q2
Wang, Y3
Yang, Y2
Kong, Y1
Peng, Y1
de Almeida, SM5
Nogueira, MB4
Nogueira, K4
Furlan, SMP1
Cretella, AMM1
Lapinski, B1
Cogo, LL1
Vidal, LRR1
Barros, NC1
Petterle, R1
Baheerathan, A1
Pitceathly, RD1
Curtis, C1
Davies, NW1
Barros, N1
Fernandes Dos Santos, A1
Custodio, G1
Petterle, RR1
Arora, S1
Abhilash, KPP1
Mitra, S1
Hazra, D1
Gunasekharan, K1
Yesudass, P1
Zhang, Y3
Xiao, X2
Zhang, J1
Gao, Z2
Ji, N2
Zhang, L3
Hill, E1
Bleck, TP1
Singh, K1
Ouyang, B2
Busl, KM1
Lefrere, B1
Plantamura, J1
Renard, C1
Ceppa, F1
Delacour, H1
Wang, L1
Li, J1
Shi, L1
Yao, M1
Guan, X1
Sanaei Dashti, A1
Alizadeh, S1
Karimi, A1
Khalifeh, M1
Shoja, SA1
Mount, HR1
Boyle, SD1
Buch, K1
Bodilsen, J1
Knudsen, A1
Larsen, L3
Helweg-Larsen, J1
Storgaard, M1
Brandt, C1
Wiese, L1
Østergaard, C1
Nielsen, H1
Lebech, AM1
Munk, M1
Poulsen, FR2
Nordström, CH2
Nielsen, TH2
Maillet, M1
De Broucker, T1
Mailles, A1
Bouzat, P1
Stahl, JP1
Zhang, G2
Yang, C1
Kang, X2
Wan, H1
Liu, Y1
Kurtaran, B1
Kuscu, F1
Ulu, A1
Inal, AS1
Komur, S1
Kibar, F1
Cetinalp, NE1
Ozsoy, KM1
Arslan, YK1
Yilmaz, DM1
Aksu, H1
Tasova, Y1
Domingues, RB1
Fernandes, GBP1
Leite, FBVM1
Senne, C1
Kul, G1
Sencan, I1
Kul, H1
Korkmaz, N1
Altunay, E1
Maskin, LP1
Capparelli, F1
Mora, A1
Hlavnicka, A1
Orellana, N1
Díaz, MF1
Wainsztein, N1
Del Castillo, M1
Schulz, M1
Jacobsen, A1
Andersen, ÅB1
Schalén, W1
Li, Y1
Ma, R1
Du, Y1
Li, F1
Fang, F1
Lv, H1
Slack, SD1
Turley, P1
Allgar, V1
Holbrook, IB1
Giulieri, S1
Chapuis-Taillard, C1
Jaton, K1
Cometta, A1
Chuard, C1
Hugli, O1
Du Pasquier, R1
Bille, J1
Meylan, P1
Manuel, O1
Marchetti, O1
Bartek, J1
Thelin, EP1
Ghatan, PH1
Glimaker, M1
Bellander, BM1
Kang, P1
Faria, FL1
de Goes Fontes, K1
Buczenko, GM1
Berto, DB1
Raboni, SM1
Vidal, LR1
Sakushima, K3
Niino, M1
Akimoto-Tsuji, S1
Yabe, I2
Sasaki, H3
Abro, AH1
Abdou, AS1
Ustadi, AM1
Saleh, AA1
Younis, NJ1
Doleh, WF1
Tang, YJ1
Zhou, FW1
Luo, ZQ1
Li, XZ1
Yan, HM1
Wang, MJ1
Huang, FR1
Yue, SJ1
Huy, NT1
Thao, NT1
Diep, DT1
Kikuchi, M1
Zamora, J1
Hirayama, K1
Prasad, K1
Sahu, JK1
Hayashino, Y1
Kawaguchi, T1
Jackson, JL1
Fukuhara, S1
Viallon, A1
Desseigne, N1
Marjollet, O1
Birynczyk, A1
Belin, M1
Guyomarch, S1
Borg, J1
Pozetto, B1
Bertrand, JC1
Zeni, F1
Blocher, J1
Eckert, I1
Elster, J1
Wiefek, J1
Eiffert, H2
Schmidt, H1
Zhang, H2
Wang, X1
Wu, J1
Grille, P1
Torres, J1
Porcires, F1
Bagnulo, H1
Chen, Z1
Zeng, A1
Chen, L1
Wu, R1
Chen, B1
Chen, M1
Bo, J1
Peng, Q1
Lu, J1
Meng, QH1
Majwala, A1
Burke, R1
Patterson, W1
Pinkerton, R1
Muzoora, C1
Wilson, LA1
Moore, CC1
Spitzer, C1
Foltys, H1
Lemmen, SW1
Block, F1
Cunha, BA1
Ramautar, R1
Somsen, GW1
de Jong, GJ1
Beloborodov, VB1
Ashwal, S1
Perkin, RM1
Thompson, JR1
Schneider, S1
Tomasi, LG1
Hiraoka, A2
Akai, J1
Tominaga, I2
Hattori, M2
Arato, T1
Miura, I1
Kushida, K1
Maeda, M1
Täuber, MG1
Sande, E1
Fournier, MA1
Tureen, JH1
Sande, MA1
Mirdha, BR1
Murugesan, K1
Bhujwala, RA1
Gupta, U1
Martynov, VA1
Roslyĭ, IM1
Kolobaeva, OV1
Pavese, P1
François, P1
Lafond, JL1
Kayemba Kay'S, S1
Bosson, JL1
Park, WS4
Chang, YS4
Lee, M3
Ko, SY1
Kang, MJ1
Han, JM1
Johnson, JR1
Wellmer, A1
Prange, J1
Gerber, J1
Zysk, G1
Lange, P1
Michel, U1
Nau, R1
Møller, K1
Strauss, GI1
Thomsen, G1
Larsen, FS1
Holm, S1
Sperling, BK1
Skinhøj, P1
Knudsen, GM1
Bryan, JP1
Scheld, WM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779]12 participants (Actual)Observational2017-08-28Completed
Early Diagnosis and Treatment Monitoring of Native and Device-associated Meningitis Using D-lactate, a Pathogen-specific Diagnostic Biomarker in Cerebrospinal Fluid[NCT05146570]842 participants (Anticipated)Interventional2021-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for lactic acid and Bacterial Meningitides

ArticleYear
CSF lactate.
    Practical neurology, 2020, Volume: 20, Issue:4

    Topics: Adult; Biomarkers; Brain Diseases; Central Nervous System Infections; Enterovirus; Female; Humans; L

2020
The diagnostic value of cerebrospinal fluid lactate for post-neurosurgical bacterial meningitis: a meta-analysis.
    BMC infectious diseases, 2016, 09-13, Volume: 16

    Topics: Biomarkers; Databases, Factual; Humans; Lactic Acid; Meningitis, Bacterial; Neurosurgical Procedures

2016
Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systemic review and meta-analysis.
    Critical care (London, England), 2010, Volume: 14, Issue:6

    Topics: Animals; Biomarkers; Diagnosis, Differential; Humans; Lactic Acid; Meningitis, Aseptic; Meningitis,

2010
Diagnostic accuracy of cerebrospinal fluid lactate for differentiating bacterial meningitis from aseptic meningitis: a meta-analysis.
    The Journal of infection, 2011, Volume: 62, Issue:4

    Topics: Diagnosis, Differential; Humans; Lactic Acid; Meningitis, Aseptic; Meningitis, Bacterial; Predictive

2011
[Revival of old diagnostic markers in the cerebrospinal fluid for the detection of infectious meningitis].
    Rinsho shinkeigaku = Clinical neurology, 2012, Volume: 52, Issue:1

    Topics: Adenosine Deaminase; Biomarkers; Humans; Lactic Acid; Meningitis, Bacterial; Practice Guidelines as

2012
[Bacterial meningitis as a complication of Fusobacterium necroforum infection in adults].
    Der Nervenarzt, 2003, Volume: 74, Issue:12

    Topics: Adult; Anti-Bacterial Agents; Blood Glucose; Cerebrospinal Fluid Proteins; Diagnosis, Differential;

2003
[Up-to-date antibacterial therapy of purulent meningitis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2006, Volume: 51, Issue:8

    Topics: Anti-Bacterial Agents; C-Reactive Protein; Calcitonin; Diagnosis, Differential; Drugs, Generic; Huma

2006
Bacterial meningitis in children: current concepts of neurologic management.
    Current problems in pediatrics, 1994, Volume: 24, Issue:8

    Topics: Adolescent; Adrenal Cortex Hormones; Algorithms; Animals; Anti-Infective Agents; Brain Edema; Cerebr

1994

Trials

1 trial available for lactic acid and Bacterial Meningitides

ArticleYear
Cerebral blood flow, oxidative metabolism and cerebrovascular carbon dioxide reactivity in patients with acute bacterial meningitis.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Blood Glucose; Brain Chemistry; Carbon Dioxide; Cerebrov

2002

Other Studies

52 other studies available for lactic acid and Bacterial Meningitides

ArticleYear
Cerebrospinal Fluid Lactate as a Differential Biomarker for Bacterial and Viral Meningitis.
    The Egyptian journal of immunology, 2023, Volume: 30, Issue:3

    Topics: Biomarkers; Diagnosis, Differential; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Viral;

2023
The value of elevated cerebrospinal fluid lactate concentrations in post-neurosurgical bacterial meningitis.
    BMC neurology, 2023, Oct-20, Volume: 23, Issue:1

    Topics: Humans; Lactic Acid; Meningitis, Bacterial; Neurosurgical Procedures; Postoperative Complications; P

2023
Cerebrospinal fluid lactate levels according to the site of puncture.
    Clinical chemistry and laboratory medicine, 2020, 01-28, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Central Nervous System Viral Diseases; Child; Electrochemical Techniq

2020
Comparison of Cerebrospinal Fluid Biomarkers for Differential Diagnosis of Acute Bacterial and Viral Meningitis with Atypical Cerebrospinal Fluid Characteristics.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2020, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Biomarkers; Blood Glucose; Child; Diagnosis, Differential; Female; Glucose; Human

2020
Comparison of cerebrospinal fluid lactate with physical, cytological, and other biochemical characteristics as prognostic factors in acute bacterial meningitis.
    Arquivos de neuro-psiquiatria, 2019, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Biomarkers; Child; Child, Preschool; Glucose; Gram-Negative Bacteria; Gram-Positi

2019
Clinical performance of amperometry compared with enzymatic ultra violet method for lactate quantification in cerebrospinal fluid.
    Diagnosis (Berlin, Germany), 2021, 11-25, Volume: 8, Issue:4

    Topics: Biomarkers; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Viral; Retrospective Studies

2021
Is cerebrospinal fluid lactate useful in differentiating scrub typhus meningitis from aseptic, bacterial and tuberculous meningitis?
    Tropical doctor, 2021, Volume: 51, Issue:1

    Topics: Adult; Cross-Sectional Studies; Diagnosis, Differential; Female; Humans; Lactic Acid; Male; Meningit

2021
Diagnostic accuracy of routine blood examinations and CSF lactate level for post-neurosurgical bacterial meningitis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 59

    Topics: Adolescent; Adult; Area Under Curve; Biomarkers; Databases, Factual; Female; Humans; Lactic Acid; Ma

2017
CSF lactate alone is not a reliable indicator of bacterial ventriculitis in patients with ventriculostomies.
    Clinical neurology and neurosurgery, 2017, Volume: 157

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cerebral Ventriculitis; Child; Child, Presch

2017
Biochemical analysis of cerebrospinal fluid in the laboratories of deployed medical treatment facilities: are Multistix 10 SG strip and iSTAT useful?
    Journal of the Royal Army Medical Corps, 2017, Volume: 163, Issue:6

    Topics: Biomarkers; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Glucose; Humans; Lactic Acid; Meningi

2017
[Predictive value of cerebrospinal fluid lactate for the diagnosis of bacterial meningitis in patients post-neurosurgical operation with blood-contaminated cerebrospinal fluid].
    Zhonghua wei zhong bing ji jiu yi xue, 2017, Volume: 29, Issue:5

    Topics: Humans; Lactic Acid; Meningitis, Bacterial; Postoperative Period; Prospective Studies; ROC Curve

2017
Diagnostic value of lactate, procalcitonin, ferritin, serum-C-reactive protein, and other biomarkers in bacterial and viral meningitis: A cross-sectional study.
    Medicine, 2017, Volume: 96, Issue:35

    Topics: Adolescent; Biomarkers; C-Reactive Protein; Calcitonin; Child; Child Health Services; Child, Prescho

2017
Aseptic and Bacterial Meningitis: Evaluation, Treatment, and Prevention.
    American family physician, 2017, Sep-01, Volume: 96, Issue:5

    Topics: Algorithms; Anti-Infective Agents; Bacterial Vaccines; C-Reactive Protein; Calcitonin; Cerebrospinal

2017
Cerebrospinal fluid lactate as a marker to differentiate between community-acquired acute bacterial meningitis and aseptic meningitis/encephalitis in adults: a Danish prospective observational cohort study.
    Infectious diseases (London, England), 2018, Volume: 50, Issue:7

    Topics: Acute Disease; Adult; Aged; Area Under Curve; Biomarkers; Cohort Studies; Community-Acquired Infecti

2018
Cerebral Metabolic Changes Related to Oxidative Metabolism in a Model of Bacterial Meningitis Induced by Lipopolysaccharide.
    Neurocritical care, 2018, Volume: 29, Issue:3

    Topics: Animals; Cerebrum; Disease Models, Animal; Female; Lactic Acid; Lipopolysaccharides; Meningitis, Bac

2018
Cerebrospinal fluid lactate concentration and bacterial encephalitis diagnosis.
    Medecine et maladies infectieuses, 2018, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cerebrospinal Fluid; Child; Child, Preschool; Female; Hu

2018
The combination of cerebrospinal fluid procalcitonin, lactate, interleukin-8 and interleukin-10 concentrations for the diagnosis of postneurosurgical bacterial meningitis: A prospective study.
    Annals of clinical biochemistry, 2019, Volume: 56, Issue:1

    Topics: Adult; Biomarkers; China; Cohort Studies; Diagnosis, Differential; Female; Humans; Interleukin-10; I

2019
The Causes of Postoperative Meningitis: The Comparison of Gram-Negative and Gram-Positive Pathogens.
    Turkish neurosurgery, 2018, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cerebrospinal Fluid Proteins; Cro

2018
Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis.
    Revista do Instituto de Medicina Tropical de Sao Paulo, 2019, Apr-18, Volume: 61

    Topics: Biomarkers; Community-Acquired Infections; Enterovirus Infections; Humans; Lactic Acid; Meningitis,

2019
The Role of Cerebrospinal Fluid Biomarkers in the Diagnosis of Post-Neurosurgical Meningitis.
    Turkish neurosurgery, 2020, Volume: 30, Issue:4

    Topics: Adult; Biomarkers; Cytokines; Female; Humans; Lactic Acid; Male; Meningitis, Bacterial; Middle Aged;

2020
Cerebrospinal fluid lactate in post-neurosurgical bacterial meningitis diagnosis.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9

    Topics: Adult; Aged; Antibiotic Prophylaxis; Data Interpretation, Statistical; Diagnosis, Differential; Fema

2013
Bedside evaluation of cerebral energy metabolism in severe community-acquired bacterial meningitis.
    Neurocritical care, 2015, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Brain Ischemia; Child; Child, Preschool; Disease Transmission, Infectious;

2015
The diagnostic value of cerebrospinal fluids procalcitonin and lactate for the differential diagnosis of post-neurosurgical bacterial meningitis and aseptic meningitis.
    Clinical biochemistry, 2015, Volume: 48, Issue:1-2

    Topics: Adolescent; Adult; Calcitonin; Calcitonin Gene-Related Peptide; Diagnosis, Differential; Female; Hum

2015
Cerebrospinal fluid lactate: measurement of an adult reference interval.
    Annals of clinical biochemistry, 2016, Volume: 53, Issue:Pt 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Chemistry Tests; Diagnosis, Differential; Femal

2016
CSF lactate for accurate diagnosis of community-acquired bacterial meningitis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2015, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Cross Infection; Female; Humans; Lactic

2015
Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Biomarkers; Brain; Cohort Studies; Female; Glucose; Humans;

2016
Quantitation of cerebrospinal fluid lactic acid in infectious and non-infectious neurological diseases.
    Clinical chemistry and laboratory medicine, 2009, Volume: 47, Issue:6

    Topics: Adult; Biomarkers; Cerebrospinal Fluid; Diagnosis, Differential; Female; Humans; Lactic Acid; Leukoc

2009
[Reliability of blood gas analyzers for measuring lactate levels in cerebrospinal fluid].
    Rinsho shinkeigaku = Clinical neurology, 2009, Volume: 49, Issue:5

    Topics: Adult; Biomarkers; Blood Gas Analysis; Diagnosis, Differential; Female; Glucose; Humans; Lactic Acid

2009
CSF lactate level: a useful diagnostic tool to differentiate acute bacterial and viral meningitis.
    JPMA. The Journal of the Pakistan Medical Association, 2009, Volume: 59, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Analysis of Variance; Cerebrospinal Fluid; Diagnosis, Differ

2009
Multiple therapeutic effects of adjunctive baicalin therapy in experimental bacterial meningitis.
    Inflammation, 2010, Volume: 33, Issue:3

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Blood Pressure; Brain Edema; Cere

2010
Cerebrospinal fluid lactate: is it a reliable and valid marker to distinguish between acute bacterial meningitis and aseptic meningitis?
    Critical care (London, England), 2011, Volume: 15, Issue:1

    Topics: Animals; Humans; Lactic Acid; Meningitis, Aseptic; Meningitis, Bacterial

2011
Meningitis in adult patients with a negative direct cerebrospinal fluid examination: value of cytochemical markers for differential diagnosis.
    Critical care (London, England), 2011, Volume: 15, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Area Under Curve; Biomarkers; C-Reactive Protein; Calcitonin

2011
Aquaporins AQP1 and AQP4 in the cerebrospinal fluid of bacterial meningitis patients.
    Neuroscience letters, 2011, Oct-17, Volume: 504, Issue:1

    Topics: Albumins; Aquaporin 1; Aquaporin 4; Case-Control Studies; Cerebrospinal Fluid Proteins; Female; Glas

2011
Meningitis in patients with a Gram-negative direct cerebrospinal fluid examination: the value of cytochemical markers for the differential diagnosis.
    Critical care (London, England), 2011, Volume: 15, Issue:5

    Topics: Calcitonin; Female; Humans; Lactic Acid; Male; Meningitis, Bacterial; Meningitis, Viral; Protein Pre

2011
Value of cerebrospinal fluid lactate for the diagnosis of bacterial meningitis in postoperative neurosurgical patients.
    Neurocirugia (Asturias, Spain), 2012, Volume: 23, Issue:4

    Topics: Cerebrospinal Fluid; Humans; Lactic Acid; Meningitis, Bacterial; Prospective Studies; Sensitivity an

2012
The clinical diagnostic significance of cerebrospinal fluid D-lactate for bacterial meningitis.
    Clinica chimica acta; international journal of clinical chemistry, 2012, Oct-09, Volume: 413, Issue:19-20

    Topics: Adolescent; Adult; Aged; Area Under Curve; Biomarkers; Child; Child, Preschool; Diagnosis, Different

2012
Handheld point-of-care cerebrospinal fluid lactate testing predicts bacterial meningitis in Uganda.
    The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:1

    Topics: Humans; Lactic Acid; Meningitis, Bacterial; Point-of-Care Systems; Uganda

2013
Distinguishing bacterial from viral meningitis: the critical importance of the CSF lactic acid levels.
    Intensive care medicine, 2006, Volume: 32, Issue:8

    Topics: Diagnosis, Differential; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Viral

2006
Direct sample injection for capillary electrophoretic determination of organic acids in cerebrospinal fluid.
    Analytical and bioanalytical chemistry, 2007, Volume: 387, Issue:1

    Topics: 3-Hydroxybutyric Acid; Buffers; Calibration; Carboxylic Acids; Citric Acid; Electroosmosis; Electrop

2007
Capillary zone electrophoretic determination of organic acids in cerebrospinal fluid from patients with central nervous system diseases.
    Journal of chromatography. A, 1994, Sep-30, Volume: 680, Issue:1

    Topics: Brain Diseases; Cerebral Infarction; Electrophoresis; Humans; Lactates; Lactic Acid; Meningitis, Bac

1994
Proton magnetic resonance spectroscopy of cerebrospinal fluid as an aid in neurological diagnosis.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1

    Topics: Adult; Aged; Central Nervous System Diseases; Cerebral Infarction; Cerebrospinal Fluid; Female; Gluc

1994
Fluid administration, brain edema, and cerebrospinal fluid lactate and glucose concentrations in experimental Escherichia coli meningitis.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:2

    Topics: Animals; Brain Edema; Escherichia coli Infections; Fluid Therapy; Glucose; Lactates; Lactic Acid; Me

1993
Evaluation of direct gas-liquid chromatography of CSF in rapid diagnosis of acute bacterial meningitis.
    The Indian journal of medical research, 1993, Volume: 97

    Topics: Acute Disease; Chromatography, Gas; Evaluation Studies as Topic; Humans; Lactates; Lactic Acid; Meni

1993
[The enzyme activity and pyruvate, lactate and 2,3-DPG levels in the erythrocytes of patients with severe forms of meningococcal infection and suppurative meningitis].
    Terapevticheskii arkhiv, 1996, Volume: 68, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Diphosphoglyceric Acids; Erythrocytes; Female; Huma

1996
[Assay of lactic acid in the cerebrospinal fluid for the diagnosis of bacterial meningitis. Strategies for the choice of discriminatory threshold].
    Presse medicale (Paris, France : 1983), 1997, Apr-12, Volume: 26, Issue:12

    Topics: Adolescent; Biomarkers; Child; Child, Preschool; Diagnosis, Differential; Discriminant Analysis; Hum

1997
Effect of induced hyperglycemia on brain cell membrane function and energy metabolism during the early phase of experimental meningitis in newborn piglets.
    Brain research, 1998, Jul-06, Volume: 798, Issue:1-2

    Topics: Animals; Animals, Newborn; Blood Glucose; Brain; Cell Membrane; Colony Count, Microbial; Energy Meta

1998
Efficacy of anti-tumor necrosis factor-alpha antibody as an adjunctive therapy in experimental Escherichia coli meningitis in the newborn piglet.
    Biology of the neonate, 1999, Volume: 75, Issue:6

    Topics: Animals; Animals, Newborn; Antibodies; Brain; Enzyme-Linked Immunosorbent Assay; Escherichia coli In

1999
Effects of decreased cerebral perfusion pressure on cerebral hemodynamics, brain cell membrane function and energy metabolism during the early phase of experimental Escherichia coli meningitis in the newborn piglet.
    Journal of Korean medical science, 2000, Volume: 15, Issue:2

    Topics: Animals; Animals, Newborn; Blood Glucose; Cell Membrane; Cerebral Cortex; Cerebrovascular Circulatio

2000
Diagnosing postneurosurgical meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:5

    Topics: Anti-Bacterial Agents; Cerebrospinal Fluid; Glucose; Humans; Lactic Acid; Leukocyte Count; Meningiti

2000
The efficacy of pentoxifylline as an anti-inflammatory agent in experimental Escherichia coli meningitis in the newborn piglet.
    Biology of the neonate, 2000, Volume: 77, Issue:4

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Brain; Cerebral Cortex; Cerebrospinal Fluid; Co

2000
D- and L-lactate in rabbit and human bacterial meningitis.
    Scandinavian journal of infectious diseases, 2001, Volume: 33, Issue:12

    Topics: Animals; Bacteria; Ceftriaxone; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Pneumococcal

2001
Therapy of experimental meningitis due to Salmonella enteritidis.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Cerebrospinal Fluid Proteins; Glucose; Humans; Lactates; Lactic Acid

1992