lactic acid has been researched along with Bacterial Eye Infections in 4 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Poor ocular bioavailability of drugs (<1%) from conventional eye drops (ie, solution, suspension, and ointments) is mainly due to the physiologic barriers of the eye." | 1.36 | Sparfloxacin-loaded PLGA nanoparticles for sustained ocular drug delivery. ( Ali, A; Aqil, M; Bhatnagar, A; Gupta, H; Khar, RK; Mittal, G, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paganelli, F | 2 |
| Cardillo, JA | 2 |
| Melo, LA | 2 |
| Lucena, DR | 1 |
| Silva, AA | 2 |
| Oliveira, AG | 2 |
| Höfling-Lima, AL | 1 |
| Nguyen, QD | 1 |
| Kuppermann, BD | 1 |
| Belfort, R | 1 |
| Gupta, H | 1 |
| Aqil, M | 1 |
| Khar, RK | 1 |
| Ali, A | 1 |
| Bhatnagar, A | 1 |
| Mittal, G | 1 |
| Pizzolitto, AC | 1 |
| Dillen, K | 1 |
| Vandervoort, J | 1 |
| Ludwig, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Comparative Study of a Single Intraoperative Sub-Tenon's Capsule Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System Versus 1% Prednisolone and 0.3% Ciprofloxacin Eyedrops for Cataract Surgery[NCT00431028] | Phase 1/Phase 2 | 140 participants (Actual) | Interventional | 2005-09-30 | Terminated (stopped due to Terminated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lactic acid and Bacterial Eye Infections
| Article | Year |
|---|---|
A single intraoperative sub-tenon's capsule injection of triamcinolone and ciprofloxacin in a controlled-release system for cataract surgery.
Topics: Aged; Anterior Chamber; Anti-Infective Agents; Anti-Inflammatory Agents; Ciprofloxacin; Connective T | 2009 |
3 other studies available for lactic acid and Bacterial Eye Infections
| Article | Year |
|---|---|
Sparfloxacin-loaded PLGA nanoparticles for sustained ocular drug delivery.
Topics: Animals; Delayed-Action Preparations; Eye Infections, Bacterial; Fluoroquinolones; Lactic Acid; Nano | 2010 |
Subconjunctival delivery of antibiotics in a controlled-release system: a novel anti-infective prophylaxis approach for cataract surgery.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotic Prophylaxis; Aqueous Humor; Bio | 2010 |
Factorial design, physicochemical characterisation and activity of ciprofloxacin-loaded PLGA nanoparticles for ocular use.
Topics: Ciprofloxacin; Eye Infections, Bacterial; Lactic Acid; Nanostructures; Polyglycolic Acid; Polylactic | 2005 |