lactic acid has been researched along with Bacteremia in 34 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, interleukin-6, procalcitonin, D-dimer, and lactic acid were found to be the most influential biomarkers with the potential to predict bacteremia." | 4.02 | Four Biomarkers-Based Artificial Neural Network Model for Accurate Early Prediction of Bacteremia with Low-level Procalcitonin. ( Chen, H; Huang, J; Qiu, J; Su, M, 2021) |
| " aeruginosa, hepatic oxygen delivery and consumption increased with early sepsis whereas there were no alterations in the concentrations of adenine nucleotides or NAD(+)/NADH within liver." | 3.72 | Sepsis-induced failure of hepatic energy metabolism. ( Asimakis, GK; Chinkes, DL; Gore, DC; Hart, DW; Rinehart, AJ, 2003) |
| "True bacteremia was detected in 899 (20." | 1.72 | Ability of lactate, procalcitonin, and criteria defining sepsis to predict 30-day mortality, bacteremia, and microbiologically confirmed infection in patients with infection suspicion treated in emergency departments. ( Beneyto Martín, P; Candel González, FJ; García-Lamberechts, EJ; González Del Castillo, J; Huarte Sanz, I; Julián-Jiménez, A; Navarro Bustos, C; Rubio-Díaz, R, 2022) |
| "Endpoints were bacteremia, septic shock, and in-hospital mortality, related to the same ED visit." | 1.62 | Lack of admission biomarkers' clinical utility in outcomes prediction in patients suspected with infection in the emergency department. ( De Ruffi, S; Gennai, S; Giordano Orsini, G; Gornet, M; Kanagaratnam, L; Leroux, P; Losset, X; Ramont, L, 2021) |
| "Subgroup analysis with septic shock, bacteraemia and high-grade infection did not affect mortality rates." | 1.56 | Timing of antibiotics in septic patients: a prospective cohort study. ( Choi, HK; Choi, WS; Jeon, JH; Moon, S; Park, DW; Seok, H; Song, J, 2020) |
| "Patients with a final diagnosis of septic shock requiring vasopressors were divided, based on initial lactate, to nonlactate expressors (0-2." | 1.38 | Prevalence and characteristics of nonlactate and lactate expressors in septic shock. ( Cocchi, MN; Donnino, MW; Dugas, AF; Gautam, S; Mackenhauer, J; Salciccioli, JD, 2012) |
| "Patients with severe sepsis and with high serum lactate levels (≥ 4 mmol/L) constitute a potential risk group that may benefit from more aggressive treatment." | 1.38 | Serum lactate is a useful predictor of death in severe sepsis in patients with pemphigus vulgaris. ( Montes de Oca-Sánchez, G; Ponce-Olivera, RM; Tirado-Sánchez, A; Vázquez-González, D, 2012) |
| "Neutropenia is a major risk factor for developing a serious infection." | 1.34 | Predictive factors of septic shock and mortality in neutropenic patients. ( Balkis, M; Hela, BA; Karima, K; Lamia, A; Mohamed, Z; Raihane, B; Ramzi, J; Yosr, B; Zaher, B, 2007) |
| "Lactic acidosis is an important complication of septic shock." | 1.31 | Blood pH level modulates organ metabolism of lactate in septic shock in dogs. ( Bautista, E; Bose, D; Chrusch, C; Duke, K; Jacobs, HK; Light, RB; Mink, SN, 2002) |
| " coli dosage (1 x 10(10) E." | 1.30 | Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis. ( Burchardi, H; Goldmann, K; Götze, O; Höpken, U; Mathes, C; Mohr, M; Oppermann, M; Siever, S, 1998) |
| "Lethal peritonitis was induced by making a 4 mm caecal perforation." | 1.29 | Endothelin concentrations in experimental sepsis: profiles of big endothelin and endothelin 1-21 in lethal peritonitis in rats. ( Giercksky, KE; Lundblad, R, 1995) |
| "Inflammation was induced by the placement of a catheter in the carotid artery." | 1.29 | Potentiation of decreased pyruvate dehydrogenase activity by inflammatory stimuli in sepsis. ( Martin, LF; Vary, TC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (32.35) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 9 (26.47) | 24.3611 |
| 2020's | 8 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Rubio-Díaz, R | 1 |
| Julián-Jiménez, A | 1 |
| González Del Castillo, J | 1 |
| García-Lamberechts, EJ | 1 |
| Huarte Sanz, I | 1 |
| Navarro Bustos, C | 1 |
| Candel González, FJ | 1 |
| Beneyto Martín, P | 1 |
| De Santos Castro, PÁ | 1 |
| Alonso Avilés, R | 1 |
| Yurttutan Uyar, N | 1 |
| Sayar, AK | 1 |
| Kocagöz, AS | 1 |
| Serdar, MA | 1 |
| Zengin, R | 1 |
| Sarıkaya, ZT | 1 |
| Kilercik, M | 1 |
| Balcı, V | 1 |
| Serteser, M | 1 |
| Contenti, J | 1 |
| Occelli, C | 1 |
| Lemoel, F | 1 |
| Ferrari, P | 1 |
| Levraut, J | 1 |
| Seok, H | 1 |
| Song, J | 1 |
| Jeon, JH | 1 |
| Choi, HK | 1 |
| Choi, WS | 1 |
| Moon, S | 1 |
| Park, DW | 1 |
| Varela-Patiño, M | 1 |
| Lopez-Izquierdo, R | 1 |
| Velayos-Garcia, P | 1 |
| Alvarez-Manzanares, J | 1 |
| Ramos-Sanchez, C | 1 |
| Carbajosa-Rodriguez, V | 1 |
| Martin-Rodriguez, F | 1 |
| Eiros, JM | 1 |
| Parente, CS | 1 |
| Sandland-Taylor, LE | 1 |
| Akhtar, W | 1 |
| Gornet, M | 1 |
| Leroux, P | 1 |
| Ramont, L | 1 |
| De Ruffi, S | 1 |
| Giordano Orsini, G | 1 |
| Losset, X | 1 |
| Kanagaratnam, L | 1 |
| Gennai, S | 1 |
| Su, M | 1 |
| Chen, H | 1 |
| Qiu, J | 1 |
| Huang, J | 1 |
| Ljungström, L | 1 |
| Pernestig, AK | 1 |
| Jacobsson, G | 1 |
| Andersson, R | 1 |
| Usener, B | 1 |
| Tilevik, D | 1 |
| Mustafić, S | 1 |
| Brkić, S | 1 |
| Prnjavorac, B | 1 |
| Sinanović, A | 1 |
| Porobić Jahić, H | 1 |
| Salkić, S | 1 |
| Gaspar, P | 1 |
| Al-Bayati, FA | 1 |
| Andrew, PW | 1 |
| Neves, AR | 1 |
| Yesilkaya, H | 1 |
| Musikatavorn, K | 1 |
| Thepnimitra, S | 1 |
| Komindr, A | 1 |
| Puttaphaisan, P | 1 |
| Rojanasarntikul, D | 1 |
| Burrell, AR | 1 |
| McLaws, ML | 1 |
| Fullick, M | 1 |
| Sullivan, RB | 1 |
| Sindhusake, D | 1 |
| Arora, R | 1 |
| Campbell, JP | 1 |
| Simon, G | 1 |
| Sahni, N | 1 |
| Dugas, AF | 1 |
| Mackenhauer, J | 1 |
| Salciccioli, JD | 1 |
| Cocchi, MN | 1 |
| Gautam, S | 1 |
| Donnino, MW | 1 |
| Tirado-Sánchez, A | 1 |
| Vázquez-González, D | 1 |
| Ponce-Olivera, RM | 1 |
| Montes de Oca-Sánchez, G | 1 |
| Chrusch, C | 1 |
| Bautista, E | 1 |
| Jacobs, HK | 1 |
| Light, RB | 1 |
| Bose, D | 1 |
| Duke, K | 1 |
| Mink, SN | 1 |
| Hart, DW | 1 |
| Gore, DC | 1 |
| Rinehart, AJ | 1 |
| Asimakis, GK | 1 |
| Chinkes, DL | 1 |
| Tsunooka, N | 1 |
| Maeyama, K | 1 |
| Hamada, Y | 1 |
| Imagawa, H | 1 |
| Takano, S | 1 |
| Watanabe, Y | 1 |
| Kawachi, K | 1 |
| Ramzi, J | 1 |
| Mohamed, Z | 1 |
| Yosr, B | 1 |
| Karima, K | 1 |
| Raihane, B | 1 |
| Lamia, A | 1 |
| Hela, BA | 1 |
| Zaher, B | 1 |
| Balkis, M | 1 |
| Ribes, S | 1 |
| Taberner, F | 1 |
| Cabellos, C | 1 |
| Tubau, F | 1 |
| Ardanuy, C | 1 |
| Gerber, J | 1 |
| Liñares, J | 1 |
| Nau, R | 1 |
| Gudiol, F | 1 |
| Störmer, M | 1 |
| Kleesiek, K | 1 |
| Dreier, J | 1 |
| Lundblad, R | 1 |
| Giercksky, KE | 1 |
| Rosenberg, RB | 1 |
| Broner, CW | 1 |
| O'Dorisio, MS | 1 |
| Stewart, KD | 1 |
| Brackett, DJ | 1 |
| Lerner, MR | 1 |
| Archer, LT | 1 |
| Wilson, MF | 1 |
| Vary, TC | 2 |
| Martin, LF | 1 |
| Dardevet, D | 1 |
| Obled, C | 1 |
| Pouyet, C | 1 |
| Breuille, D | 1 |
| Grizard, J | 1 |
| Heemskerk, AE | 1 |
| Huisman, E | 1 |
| van Lambalgen, AA | 1 |
| van den Bos, GC | 1 |
| Hennekes, M | 1 |
| Thijs, LG | 2 |
| Tangelder, GJ | 1 |
| Balteskard, L | 1 |
| Unneberg, K | 1 |
| Mjaaland, M | 1 |
| Sager, G | 1 |
| Jenssen, TG | 1 |
| Revhaug, A | 1 |
| Mohr, M | 1 |
| Höpken, U | 1 |
| Oppermann, M | 1 |
| Mathes, C | 1 |
| Goldmann, K | 1 |
| Siever, S | 1 |
| Götze, O | 1 |
| Burchardi, H | 1 |
| Neal, TJ | 1 |
| Corkill, JE | 1 |
| Bennett, KJ | 1 |
| Yoxall, CW | 1 |
| Lorente, JA | 1 |
| Delgado, MA | 1 |
| Tejedor, C | 1 |
| Mon, E | 1 |
| Hervás, M | 1 |
| Pascual, T | 1 |
| Fernández-Segoviano, P | 1 |
| Rieppi, G | 1 |
| Soler, A | 1 |
| Ayuso, D | 1 |
| Esteban, A | 1 |
| Hack, CE | 1 |
| Hart, M | 1 |
| van Schijndel, RJ | 1 |
| Eerenberg, AJ | 1 |
| Nuijens, JH | 1 |
| Aarden, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Lactate Level in Prediction of Patients'Acute Gastrointestinal Bleeding Admissions to Intensive Care Unit, Interventions and Short Term Outcomes[NCT04104425] | 300 participants (Actual) | Observational | 2020-01-15 | Completed | |||
| Can Venous Lactate Predict the Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients Without Hemodynamic Shock in Emergency Department?[NCT01947127] | 458 participants (Actual) | Observational [Patient Registry] | 2013-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Electronic database retrieval of in- and outpatient clinical records together with telephone follow-ups to the patients or their contact personnel are employed to every case in the next 30 days after the day of presentation to the emergency department to identify the deceased cases. All-cause mortality rates of each cohort will be compared by the survival analysis. (NCT01947127)
Timeframe: 30 days after the day of presentation to the emergency department
| Intervention | participants (Number) |
|---|---|
| High Lactate | 18 |
| Low Lactate | 13 |
Numbers of days spent in the hospital since the emergency department arrival to hospital discharge (NCT01947127)
Timeframe: Patients will be followed for the duration of hospital stay, an expected average of 7 days
| Intervention | Days (Median) |
|---|---|
| High Lactate | 6 |
| Low Lactate | 3 |
Proportion of the patients in each cohort who require vasopressor/mechanical ventilator to maintain their vital signs in the next 72 hours after venous lactate measurement. (NCT01947127)
Timeframe: 72 hours after venous lactate measurement
| Intervention | participants (Number) |
|---|---|
| High Lactate | 53 |
| Low Lactate | 21 |
34 other studies available for lactic acid and Bacteremia
| Article | Year |
|---|---|
Ability of lactate, procalcitonin, and criteria defining sepsis to predict 30-day mortality, bacteremia, and microbiologically confirmed infection in patients with infection suspicion treated in emergency departments.
Topics: Adolescent; Area Under Curve; Bacteremia; Emergency Service, Hospital; Female; Humans; Lactic Acid; | 2022 |
On the ability of lactate, procalcitonin, and criteria defining sepsis to predict 30-day mortality, bacteremia, and microbiologically confirmed infection in patients with suspected infection treated in emergency departments.
Topics: Bacteremia; Emergency Service, Hospital; Humans; Lactic Acid; Procalcitonin; Sepsis | 2022 |
Sepsis biomarkers for early diagnosis of bacteremia in emergency department.
Topics: Adult; Bacteremia; Biomarkers; C-Reactive Protein; Calcitonin; Early Diagnosis; Emergency Service, H | 2023 |
Presepsin versus other biomarkers to predict sepsis and septic shock in patients with infection defined by Sepsis-3 criteria: the PREDI study of diagnostic accuracy.
Topics: Aged; Area Under Curve; Bacteremia; Biomarkers; C-Reactive Protein; Emergency Service, Hospital; Fem | 2019 |
Timing of antibiotics in septic patients: a prospective cohort study.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Female; Humans; Lactic Acid; Male; Middle Aged; Mortality; | 2020 |
Usefulness of infection biomarkers for diagnosing bacteremia in patients with a sepsis code in the emergency department.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Area Under Curve; Bacteremia; Biomarkers; C-Reactive Protei | 2020 |
Diagnostic challenge: an atypical presentation of infective endocarditis.
Topics: Bacteremia; Blood Culture; C-Reactive Protein; Diagnosis, Differential; Diarrhea; Dysentery; Early W | 2021 |
Lack of admission biomarkers' clinical utility in outcomes prediction in patients suspected with infection in the emergency department.
Topics: Adult; Aged; Aged, 80 and over; Bacteremia; Biomarkers; C-Reactive Protein; Emergency Service, Hospi | 2021 |
Four Biomarkers-Based Artificial Neural Network Model for Accurate Early Prediction of Bacteremia with Low-level Procalcitonin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Bacteria; Biomarkers; C-Reactive Protein; Ca | 2021 |
Diagnostic accuracy of procalcitonin, neutrophil-lymphocyte count ratio, C-reactive protein, and lactate in patients with suspected bacterial sepsis.
Topics: Aged; Aged, 80 and over; Area Under Curve; Bacteremia; Biomarkers; C-Reactive Protein; Calcitonin; D | 2017 |
Diagnostic and prognostic value of procalcitonin in patients with sepsis.
Topics: Area Under Curve; Bacteremia; Bacteria; Biomarkers; Blood Culture; C-Reactive Protein; Calcitonin; H | 2018 |
Lactate dehydrogenase is the key enzyme for pneumococcal pyruvate metabolism and pneumococcal survival in blood.
Topics: Animals; Bacteremia; Blood; Disease Models, Animal; Female; Fermentation; Gene Deletion; L-Lactate D | 2014 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
Venous lactate in predicting the need for intensive care unit and mortality among nonelderly sepsis patients with stable hemodynamic.
Topics: Adult; Bacteremia; Female; Humans; Immunosuppressive Agents; Intensive Care Units; Lactic Acid; Male | 2015 |
SEPSIS KILLS: early intervention saves lives.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Biomarkers; Blood; Early Diagnosis; Emergency Service, Hosp | 2016 |
Does serum procalcitonin aid in the diagnosis of bloodstream infection regardless of whether patients exhibit the systemic inflammatory response syndrome?
Topics: Aged; Aged, 80 and over; Area Under Curve; Bacteremia; Calcitonin; Female; Humans; Lactic Acid; Male | 2017 |
Prevalence and characteristics of nonlactate and lactate expressors in septic shock.
Topics: Aged; Aged, 80 and over; Bacteremia; Comorbidity; Emergency Service, Hospital; Female; Hospitals, Un | 2012 |
Serum lactate is a useful predictor of death in severe sepsis in patients with pemphigus vulgaris.
Topics: Adult; Bacteremia; Comorbidity; Female; Humans; Lactic Acid; Logistic Models; Male; Pemphigus; Progn | 2012 |
Blood pH level modulates organ metabolism of lactate in septic shock in dogs.
Topics: Animals; Bacteremia; Blood Gas Analysis; Disease Models, Animal; Dogs; Escherichia coli Infections; | 2002 |
Sepsis-induced failure of hepatic energy metabolism.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bacteremia; Blood F | 2003 |
Bacterial translocation secondary to small intestinal mucosal ischemia during cardiopulmonary bypass. Measurement by diamine oxidase and peptidoglycan.
Topics: Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Bacteremia; Bacterial Translocation; Bio | 2004 |
Predictive factors of septic shock and mortality in neutropenic patients.
Topics: Adult; Bacteremia; Bacteria; Bicarbonates; Female; Fever; Humans; Lactic Acid; Leukemia, Myeloid, Ac | 2007 |
Contribution of capsular and clonal types and beta-lactam resistance to the severity of experimental pneumococcal meningitis.
Topics: Adult; Animals; Bacteremia; Bacterial Capsules; beta-Lactam Resistance; Blood; Cerebrospinal Fluid; | 2008 |
pH value promotes growth of Staphylococcus epidermidis in platelet concentrates.
Topics: Bacteremia; Blood Donors; Blood Platelets; Blood Preservation; Citrates; Cryopreservation; Humans; H | 2008 |
Endothelin concentrations in experimental sepsis: profiles of big endothelin and endothelin 1-21 in lethal peritonitis in rats.
Topics: Animals; Bacteremia; Endothelin-1; Endothelins; Gram-Negative Bacterial Infections; Interleukin-6; L | 1995 |
Modulation of cyclic guanosine monophosphate production during Escherichia coli septic shock.
Topics: Animals; Arginine; Bacteremia; Carbon Dioxide; Cyclic GMP; Escherichia coli Infections; Lactates; La | 1994 |
Comparison of Staphylococcus aureus and Escherichia coli infusion in conscious rats.
Topics: Animals; Bacteremia; Blood Glucose; Carbon Dioxide; Cardiac Output; Escherichia coli; Escherichia co | 1994 |
Potentiation of decreased pyruvate dehydrogenase activity by inflammatory stimuli in sepsis.
Topics: Animals; Bacteremia; Bacterial Infections; Catheters, Indwelling; Disease Models, Animal; Inflammati | 1993 |
Modulation of skeletal muscle lactate metabolism following bacteremia by insulin or insulin-like growth factor-I: effects of pentoxifylline.
Topics: Animals; Bacteremia; Escherichia coli; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Mus | 1997 |
Renal function and oxygen consumption during bacteraemia and endotoxaemia in rats.
Topics: Animals; Bacteremia; Endotoxins; Escherichia coli; Kidney; Lactic Acid; Male; Natriuresis; Oxygen Co | 1997 |
Treatment with growth hormone and insulin-like growth factor-1 in septicemia: effects on carbohydrate metabolism.
Topics: Alanine; Animals; Bacteremia; Blood Glucose; Calorimetry, Indirect; Carbohydrate Metabolism; Disease | 1998 |
Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis.
Topics: Animals; Antibodies, Monoclonal; Bacteremia; Blood Pressure; Complement C5a; Disease Models, Animal; | 1998 |
Serratia marcescens pseudobacteraemia in neonates associated with a contaminated blood glucose/lactate analyzer confirmed by molecular typing.
Topics: Bacteremia; Blood Glucose; Cross Infection; Diagnostic Errors; Electrophoresis, Gel, Pulsed-Field; E | 1999 |
Modulation of systemic hemodynamics by exogenous L-arginine in normal and bacteremic sheep.
Topics: Acidosis; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; | 1999 |
Interleukin-8 in sepsis: relation to shock and inflammatory mediators.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin; Bacteremia; Blood Pressure; Complem | 1992 |