lactic acid has been researched along with Autosomal Dominant Myotubular Myopathy in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "X-linked myotubular myopathy is a congenital myopathy due to mutation in the MTM1 gene, encoding myotubularin." | 1.34 | Diagnosis of myotubular myopathy in the oldest known manifesting female carrier: a clinical and genetic study. ( Biancalana, V; Cossée, M; Dubas, F; Pénisson-Besnier, I; Reynier, P, 2007) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, CB | 1 |
| Dolezal, BA | 1 |
| Riley, M | 1 |
| Verity, MA | 1 |
| Shieh, PB | 1 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Vissing, J | 1 |
| Pénisson-Besnier, I | 1 |
| Biancalana, V | 1 |
| Reynier, P | 1 |
| Cossée, M | 1 |
| Dubas, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| Prospective Study of Adverse Event Rates in Males With X-Linked Myotubular Myopathy[NCT01840657] | 33 participants (Actual) | Observational | 2013-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for lactic acid and Autosomal Dominant Myotubular Myopathy
| Article | Year |
|---|---|
Reverse fiber type disproportion: A distinct metabolic myopathy.
Topics: Adolescent; Adult; Ammonia; Biopsy; Creatine Kinase; Exercise; Female; Heart Rate; Humans; Lactic Ac | 2016 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
Diagnosis of myotubular myopathy in the oldest known manifesting female carrier: a clinical and genetic study.
Topics: Aged, 80 and over; Blepharoptosis; Blotting, Southern; Chromosomes, Human, X; Creatine Kinase; DNA; | 2007 |