Page last updated: 2024-10-17

lactic acid and Autoimmune Disease

lactic acid has been researched along with Autoimmune Disease in 11 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"We measured concentrations of kynurenine (Kyn) and tryptophan (Trp) in 221 cerebrospinal fluid samples from patients with bacterial and viral (due to herpes simplex, varicella zoster, and enteroviruses) meningitis/encephalitis, neuroborreliosis, autoimmune neuroinflammation (due to anti-N-methyl-D-aspartate receptor [NMDA] encephalitis and multiple sclerosis), and noninflamed controls (ie, individuals with Bell palsy, normal pressure hydrocephalus, or Tourette syndrome)."7.91Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections. ( Kaever, V; Kuhn, M; Müller-Vahl, K; Novoselova, N; Pessler, F; Seegers, L; Skripuletz, T; Stangel, M; Sühs, KW; Trebst, C, 2019)
"The therapeutic effects of betamethasone phosphate (BP) encapsulated in biocompatible and biodegradable blended nanoparticles of poly(lactic acid) (PLA) homopolymers and PEG-block-PLA copolymers (stealth nanosteroids) were examined in an experimental autoimmune uveoretinitis (EAU) model in Lewis rats."7.77Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis. ( Akiyama, G; Higaki, M; Ishihara, T; Sakai, T; Tsuneoka, H, 2011)
" In this study, we evaluated the effects of intravenously administered poly(lactic acid) nanoparticles encapsulating betamethasone phosphate (BP-PLA NPs) on experimental autoimmune uveoretinitis (EAU) in Lewis rats."7.73Treatment of experimental autoimmune uveoretinitis with poly(lactic acid) nanoparticles encapsulating betamethasone phosphate. ( Higaki, M; Ishihara, T; Kitahara, K; Kohno, H; Matsushima, M; Mizushima, Y; Saito, S; Sakai, T, 2006)
"We measured concentrations of kynurenine (Kyn) and tryptophan (Trp) in 221 cerebrospinal fluid samples from patients with bacterial and viral (due to herpes simplex, varicella zoster, and enteroviruses) meningitis/encephalitis, neuroborreliosis, autoimmune neuroinflammation (due to anti-N-methyl-D-aspartate receptor [NMDA] encephalitis and multiple sclerosis), and noninflamed controls (ie, individuals with Bell palsy, normal pressure hydrocephalus, or Tourette syndrome)."3.91Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections. ( Kaever, V; Kuhn, M; Müller-Vahl, K; Novoselova, N; Pessler, F; Seegers, L; Skripuletz, T; Stangel, M; Sühs, KW; Trebst, C, 2019)
"The therapeutic effects of betamethasone phosphate (BP) encapsulated in biocompatible and biodegradable blended nanoparticles of poly(lactic acid) (PLA) homopolymers and PEG-block-PLA copolymers (stealth nanosteroids) were examined in an experimental autoimmune uveoretinitis (EAU) model in Lewis rats."3.77Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis. ( Akiyama, G; Higaki, M; Ishihara, T; Sakai, T; Tsuneoka, H, 2011)
" In this study, we evaluated the effects of intravenously administered poly(lactic acid) nanoparticles encapsulating betamethasone phosphate (BP-PLA NPs) on experimental autoimmune uveoretinitis (EAU) in Lewis rats."3.73Treatment of experimental autoimmune uveoretinitis with poly(lactic acid) nanoparticles encapsulating betamethasone phosphate. ( Higaki, M; Ishihara, T; Kitahara, K; Kohno, H; Matsushima, M; Mizushima, Y; Saito, S; Sakai, T, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Sanmarco, LM1
Rone, JM1
Polonio, CM1
Fernandez Lahore, G1
Giovannoni, F1
Ferrara, K1
Gutierrez-Vazquez, C1
Li, N1
Sokolovska, A1
Plasencia, A1
Faust Akl, C1
Nanda, P1
Heck, ES1
Li, Z1
Lee, HG1
Chao, CC1
Rejano-Gordillo, CM1
Fonseca-Castro, PH1
Illouz, T1
Linnerbauer, M1
Kenison, JE1
Barilla, RM1
Farrenkopf, D1
Stevens, NA1
Piester, G1
Chung, EN1
Dailey, L1
Kuchroo, VK1
Hava, D1
Wheeler, MA1
Clish, C1
Nowarski, R1
Balsa, E1
Lora, JM1
Quintana, FJ1
Marin, E1
Bouchet-Delbos, L1
Renoult, O1
Louvet, C1
Nerriere-Daguin, V1
Managh, AJ1
Even, A1
Giraud, M1
Vu Manh, TP1
Aguesse, A1
Bériou, G1
Chiffoleau, E1
Alliot-Licht, B1
Prieur, X1
Croyal, M1
Hutchinson, JA1
Obermajer, N1
Geissler, EK1
Vanhove, B1
Blancho, G1
Dalod, M1
Josien, R1
Pecqueur, C1
Cuturi, MC1
Moreau, A1
Christofi, M1
Le Sommer, S1
Mölzer, C1
Klaska, IP1
Kuffova, L1
Forrester, JV1
Sühs, KW1
Novoselova, N1
Kuhn, M1
Seegers, L1
Kaever, V1
Müller-Vahl, K1
Trebst, C1
Skripuletz, T1
Stangel, M1
Pessler, F1
Yang, Z1
Matteson, EL1
Goronzy, JJ1
Weyand, CM1
Cano-Garrido, O1
Seras-Franzoso, J1
Garcia-Fruitós, E1
Pucino, V1
Bombardieri, M1
Pitzalis, C1
Mauro, C1
Basarkar, A1
Singh, J1
Sakai, T2
Ishihara, T2
Higaki, M2
Akiyama, G1
Tsuneoka, H1
Kohno, H1
Saito, S1
Matsushima, M1
Mizushima, Y1
Kitahara, K1
Korn, T1
Rao, M1
Magnus, T1

Reviews

4 reviews available for lactic acid and Autoimmune Disease

ArticleYear
T-cell metabolism in autoimmune disease.
    Arthritis research & therapy, 2015, Feb-11, Volume: 17

    Topics: Adenosine Triphosphate; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Lactic Acid; Lupus Eryth

2015
Lactic acid bacteria: reviewing the potential of a promising delivery live vector for biomedical purposes.
    Microbial cell factories, 2015, Sep-16, Volume: 14

    Topics: Autoimmune Diseases; Drug Delivery Systems; Gastrointestinal Tract; Genetic Vectors; Gram-Positive B

2015
Lactate at the crossroads of metabolism, inflammation, and autoimmunity.
    European journal of immunology, 2017, Volume: 47, Issue:1

    Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Autoimmunity; Energy Metabolism; Humans; Immune

2017
Autoimmune modulation of astrocyte-mediated homeostasis.
    Neuromolecular medicine, 2007, Volume: 9, Issue:1

    Topics: Animals; Antigen Presentation; Astrocytes; Autoimmune Diseases; Autoimmunity; Biological Transport,

2007

Other Studies

7 other studies available for lactic acid and Autoimmune Disease

ArticleYear
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
    Nature, 2023, Volume: 620, Issue:7975

    Topics: Autoimmune Diseases; Autoimmunity; Central Nervous System; Dendritic Cells; Feedback, Physiological;

2023
Human Tolerogenic Dendritic Cells Regulate Immune Responses through Lactate Synthesis.
    Cell metabolism, 2019, 12-03, Volume: 30, Issue:6

    Topics: Animals; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Cells, Cultured; Dendritic Cells; Female;

2019
Low-dose 2-deoxy glucose stabilises tolerogenic dendritic cells and generates potent in vivo immunosuppressive effects.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:6

    Topics: Animals; Antigens, Bacterial; Autoimmune Diseases; B7-2 Antigen; Bone Marrow Cells; CD4-Positive T-L

2021
Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections.
    The Journal of infectious diseases, 2019, 06-05, Volume: 220, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Biomarkers; Central Nervous System

2019
Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice.
    Pharmaceutical research, 2009, Volume: 26, Issue:1

    Topics: Animals; Autoimmune Diseases; Blood Glucose; Buffers; Diabetes Mellitus; Drug Delivery Systems; Exci

2009
Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis.
    Investigative ophthalmology & visual science, 2011, Mar-18, Volume: 52, Issue:3

    Topics: Animals; Autoimmune Diseases; Betamethasone; Biocompatible Materials; Biological Availability; Delay

2011
Treatment of experimental autoimmune uveoretinitis with poly(lactic acid) nanoparticles encapsulating betamethasone phosphate.
    Experimental eye research, 2006, Volume: 82, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Betamethasone; Choroid; Delayed-Action Prepa

2006