Page last updated: 2024-10-17

lactic acid and Autoimmune Diabetes

lactic acid has been researched along with Autoimmune Diabetes in 130 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"The objective was to assess glucose, lactate, glycerol, and pyruvate concentrations in the interstitial fluid of the adipose tissue as well as the glucose relative recovery coefficient in reference to capillary blood (RC) during the first two days of the standard treatment of diabetic ketoacidosis (DKA) in patients with type 1 and type 2 diabetes."7.79Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2013)
"A 53-year-old man with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) underwent a gastrectomy."7.74Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy. ( Fujita, Y; Katsuya, H; Sasano, H; Sasano, N; So, M; Sobue, K, 2007)
"The objective was to assess glucose, lactate, glycerol, and pyruvate concentrations in the interstitial fluid of the adipose tissue as well as the glucose relative recovery coefficient in reference to capillary blood (RC) during the first two days of the standard treatment of diabetic ketoacidosis (DKA) in patients with type 1 and type 2 diabetes."3.79Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2013)
"Maternally inherited diabetes and deafness (MIDD) and myoencephalopathy, lactic acidosis, stroke-like episodes (MELAS) syndromes are characterized by the same A3243G mutation of mitochondrial DNA (mtDNA)."3.75Brain anomalies in maternally inherited diabetes and deafness syndrome. ( Cozzone, PJ; Felician, O; Fromont, I; Lebail, B; Lefur, Y; Mancini, J; Nicoli, F; Paquis-Flucklinger, V; Valéro, R; Vialettes, B, 2009)
"A 53-year-old man with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) underwent a gastrectomy."3.74Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy. ( Fujita, Y; Katsuya, H; Sasano, H; Sasano, N; So, M; Sobue, K, 2007)
" IDDM children exhibited pronounced lactic acidosis under stress (pH: group 2, 7."3.69Sympathetic-adrenergic activity and acid-base regulation under acute physical stress in type I (insulin-dependent) diabetic children. ( Körner, A; Madácsy, L; Miltényi, M; Nagy, I; Szabó, A; Szücs, L; Tulassay, T; Yasar, SA, 1994)
"Measurements were made of lactate, pyruvate and 2,3-diphosphoglycerate in 69 children admitted to the hospital in a state of diabetic ketoacidosis of different intensity."3.68[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus]. ( Baturin, AA; Marchenko, LF; Terent'eva, EA, 1991)
"Adults with type 1 diabetes established on insulin pumps undertook HIIE and MIE stages in random order during automated insulin delivery via a closed-loop system (Medtronic)."2.84Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study. ( Gerche, A; Grosman, B; Horsburgh, JC; Jayawardene, DC; Jenkins, AJ; Kurtz, N; MacIsaac, RJ; McAuley, SA; O'Neal, DN; Roberts, TJ; Roy, A; Ward, GM, 2017)
"IHE in individuals with type 1 diabetes without insulin adaptation reduced exogenous glucose requirements compared with CONT."2.82Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study. ( Bally, L; Boesch, C; Buehler, T; Ciller, C; Dokumaci, AS; Feller, K; Loher, H; Paganini, D; Pasi, N; Rosset, R; Speck, C; Stettler, C; Tappy, L; Wilhelm, M; Zueger, T, 2016)
"Nine individuals with type 1 diabetes were tested on two separate occasions, during which either a 30-min MOD or IHE protocol was performed under conditions of a euglycemic clamp in combination with the infusion of [6,6-(2)H]glucose."2.73Effect of intermittent high-intensity compared with continuous moderate exercise on glucose production and utilization in individuals with type 1 diabetes. ( Fournier, PA; Guelfi, KJ; Jones, TW; Ratnam, N; Smythe, GA, 2007)
"Eighteen patients with type 1 diabetes mellitus (mean age 36."2.73Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study. ( Bock, G; Bodenlenz, M; Fürst-Recktenwald, S; Horvath, K; Magnes, C; Pieber, TR; Plank, J; Regittnig, W; Sinner, F; Theobald, K; Wutte, A, 2008)
"Glycerol concentration was 267 +/- 41 micromol/L and 133 +/- 40 micromol/L in PF and venous blood, respectively (P = 0."2.73Microdialysis technique as a monitoring system for acute complications of diabetes. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2008)
"In the study, seven male subjects with type 1 diabetes injected their normal insulin dose and ate their usual breakfast."2.72The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes. ( Bussau, VA; Ferreira, LD; Fournier, PA; Jones, TW, 2006)
"Seven healthy individuals with type 1 diabetes were tested on two separate occasions, during which either a 30-min MOD or IHE protocol was performed."2.71The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes. ( Fournier, PA; Guelfi, KJ; Jones, TW, 2005)
"Nine people with type 1 diabetes and normal awareness of hypoglycemia underwent two hyperinsulinemic euglycemic-hypoglycemic (3."1.72Effect of lactate administration on cerebral blood flow during hypoglycemia in people with type 1 diabetes. ( de Galan, BE; Grandjean, J; Heerschap, A; Tack, CJ; van Asten, JJA; van der Graaf, M; van Meijel, LA; Wiegers, EC, 2022)
"Exercise is part of type 1 diabetes (T1D) management due to its cardiovascular and metabolic benefits."1.72Trends of glucose, lactate and ketones during anaerobic and aerobic exercise in subjects with type 1 diabetes: The ACTION-1 study. ( Braspenning, R; De Block, C; De Ridder, F; De Winter, B; Delbeke, D; Ledeganck, KJ; Pieralice, S; Pozzilli, P; Renard, E; Vissers, D, 2022)
"Treatment with metformin improved these parameters."1.62Metformin mitigates impaired testicular lactate transport/utilisation and improves sexual behaviour in streptozotocin-induced diabetic rats. ( Abu Bakar, AB; Ahmad, A; Mohamed, M; Nna, VU, 2021)
"Sixteen children and adolescents with type 1 diabetes (T1D) had blood samples obtained, 6-12 hours into treatment, at three weeks and three months post start of treatment."1.56Soluble Receptor for Glycation End-products Concentration Increases Following the Treatment of Severe Diabetic Ketoacidosis ( Artlett, CM; Blum, J; Hoffman, WH; Ikeda, T; Ishikawa, T; Tani, N, 2020)
"In total, 189 children with type 1 diabetes from 11 diabetes care centers, in Poland, participated in a football tournament in 3 age categories: 7-9 (21."1.51Assessment of Safety and Glycemic Control During Football Tournament in Children and Adolescents With Type 1 Diabetes-Results of GoalDiab Study. ( Adamska, A; Araszkiewicz, A; Biegański, G; Domaszewska, K; Gawrecki, A; Jarosz-Chobot, P; Klupa, T; Konarski, J; Michalak, A; Naskręt, D; Skowrońska, B; Szadkowska, A; Szypowska, A; Zozulińska-Ziółkiewicz, D, 2019)
"People with type 1 diabetes typically experience a decrease in blood glucose levels, particularly during low- and moderate-intensity exercises."1.46Atypical blood glucose response to continuous and interval exercise in a person with type 1 diabetes: a case report. ( Bracken, RM; Eckstein, ML; Groeschl, W; Hofmann, P; Koehler, G; Moser, O; Mueller, A; Pieber, TR; Tschakert, G, 2017)
"Islet transplantation is a promising treatment for human type 1 diabetes mellitus."1.39PLG scaffold delivered antigen-specific regulatory T cells induce systemic tolerance in autoimmune diabetes. ( Goodman, A; Gower, RM; Graham, JG; Houlihan, J; Luo, X; Pothoven, K; Shea, LD; Wang, S; Zhang, X, 2013)
"Thus, adolescents with type 1 diabetes can participate in physical activity on the same terms as healthy peers."1.38Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls. ( Adolfsson, P; Albertsson-Wikland, K; Lindblad, B; Nilsson, S, 2012)
"Six individuals with Type 1 diabetes and 10 matched controls participated in the expedition."1.32Metabolic and cardiovascular parameters in type 1 diabetes at extreme altitude. ( Avogaro, A; Biasin, R; Casara, D; Merlo, L; Noventa, D; Pavan, P; Ponchia, A; Sarto, P, 2004)
"Eight male adolescents with IDDM and eight healthy controls of similar age, weight, and VO2peak cycled for 60 min at 60%VO2peak on two occasions spaced 1-4 wk apart."1.31Perceived exertion with glucose ingestion in adolescent males with IDDM. ( Bar-Or, O; Gerstein, HC; Heigenhauser, GJ; Riddell, MC, 2000)
"We conclude that DAN, long IDDM duration per se, and antecedent recent hypoglycemia contribute to different extents to impaired adrenaline responses and hypoglycemia unawareness."1.30Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation. ( Bolli, GB; Bottini, P; Brunetti, P; Ciofetta, M; Del Sindaco, P; Di Vincenzo, A; Fanelli, C; Lalli, C; Lepore, M; Pampanelli, S; Porcellati, F, 1997)
" This was associated with a 3 fold increase in insulin concentrations, even in the presence of adrenaline at a dosage which inhibits glucose-induced insulin release."1.30Glucose-lowering effect of BTS 67 582. ( Bailey, CJ; Page, T, 1997)
"Fatigue was assessed every 10 min using the Borg scale for rating of perceived exertion."1.30Well-being, cerebral function, and physical fatigue after nocturnal hypoglycemia in IDDM. ( King, P; Kong, MF; Macdonald, IA; Parkin, H; Tattersall, RB, 1998)
"From 1981 to 1994, 112 IDDM patients were on IT."1.29Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia. ( Annibale, B; Bartocci, L; Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lalli, C; Lepore, M; Modarelli, F; Pampanelli, S; Rambotti, AM; Sindaco, PD, 1996)
"Biguanides were found to be conducive to normalization of thrombelastogram values, not elevating the blood serum content of lactic acid even after exercise test."1.28[Effect of biguanides on the indicators of thrombelastography and the level of lactic acid in diabetes mellitus]. ( Babenko, AIu; Blagosklonnaia, IaV; Krasil'nikova, EI; Zaĭed, N, 1990)
"Another six IDDM patients and six normal subjects were given saline, lactic acid, and saline infusions at the same rates of infusion after an overnight fast during euglycemic insulin-glucose clamp."1.27Metabolic control of kidney hemodynamics in normal and insulin-dependent diabetic subjects. Effects of acetoacetic, lactic, and acetic acids. ( Avogaro, A; Doria, A; Duner, E; Fioretto, P; Iori, E; Merkel, C; Nosadini, R; Trevisan, R; Valerio, A; Velussi, M, 1987)
"The patients with IDDM exhibited threefold greater increments in plasma glucose, largely the result of greater increments in glucose production."1.27Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine ( Berk, MA; Clutter, WE; Cryer, PE; Gingerich, RP; Parvin, CA; Shah, SD; Skor, D, 1985)

Research

Studies (130)

TimeframeStudies, this research(%)All Research%
pre-199028 (21.54)18.7374
1990's24 (18.46)18.2507
2000's29 (22.31)29.6817
2010's37 (28.46)24.3611
2020's12 (9.23)2.80

Authors

AuthorsStudies
Flotyńska, J1
Gawrecki, A2
Araszkiewicz, A2
Parchimowicz, M1
Michalski, M1
Różańska, O1
Stopczyńska-Szymecka, M1
Kamiński, M1
Cieluch, A1
Biegański, G2
Michalak, A2
Domaszewska, K2
Zozulińska-Ziółkiewicz, D2
van Meijel, LA1
van Asten, JJA1
Grandjean, J1
Heerschap, A2
Tack, CJ4
van der Graaf, M3
Wiegers, EC3
de Galan, BE4
De Ridder, F1
Ledeganck, KJ1
De Winter, B1
Braspenning, R1
Delbeke, D1
Renard, E1
Pozzilli, P2
Pieralice, S1
Vissers, D1
De Block, C1
Chehayeb, RJ1
Ilagan-Ying, YC1
Sankey, C1
Young, GM1
Jacobs, PG1
Tyler, NS1
Nguyen, TP1
Castle, JR1
Wilson, LM1
Branigan, D1
Gabo, V1
Guillot, FH1
Riddell, MC2
El Youssef, J1
Hoffman, WH1
Ishikawa, T1
Blum, J1
Tani, N1
Ikeda, T1
Artlett, CM1
Morrow, B1
Malkoc, A1
Gong, T1
Probst, D1
Lin, C1
Sen, A1
La Belle, JT1
Jenei, K1
Szatmári, I1
Szabó, E1
Mariam, A1
Luczay, A1
Zsidegh, P1
Tóth-Heyn, P1
Prudhomme, T1
Kervella, D1
Ogbemudia, AE1
Gauttier, V1
Renaudin, K1
Mesnard, B1
Minault, D1
Hervouet, J1
Le Bas-Bernardet, S1
Cantarovich, D1
Karam, G1
Blancho, G1
Branchereau, J1
McCarthy, O1
Pitt, J1
Wellman, B1
Eckstein, ML2
Moser, O4
Bain, SC2
Bracken, RM3
Matejko, B1
Tota, Ł1
Mrozińska, S1
Morawska, M1
Pałka, T1
Kieć-Wilk, B1
Klupa, T2
Malecki, MT1
Huang, YN1
Chiang, SL1
Lin, YJ1
Liu, SC1
Li, YH1
Liao, YC1
Lee, MR1
Su, PH1
Tsai, FJ1
Hung, HC1
Wang, CH1
Rooijackers, HM3
Thijssen, DH1
Kessels, RPC1
Jayawardene, DC1
McAuley, SA1
Horsburgh, JC1
Gerche, A1
Jenkins, AJ1
Ward, GM1
MacIsaac, RJ1
Roberts, TJ1
Grosman, B1
Kurtz, N1
Roy, A1
O'Neal, DN1
Tschakert, G3
Mueller, A3
Groeschl, W3
Pieber, TR4
Koehler, G3
Hofmann, P3
Thondawada, M1
Wadhwani, AD1
S Palanisamy, D1
Rathore, HS1
Gupta, RC1
Chintamaneni, PK1
Samanta, MK1
Dubala, A1
Varma, S1
Krishnamurthy, PT1
Gowthamarajan, K1
Obach, M1
Hosseini-Tabatabaei, A1
Montane, J1
Wind, K1
Soukhatcheva, G1
Dai, D1
Priatel, JJ1
Orban, PC1
Verchere, CB1
Szadkowska, A1
Konarski, J1
Skowrońska, B1
Adamska, A1
Naskręt, D1
Jarosz-Chobot, P1
Szypowska, A1
Márquez, A1
Aymerich, J1
Dei, M1
Rodríguez-Rodríguez, R1
Vázquez-Carrera, M1
Pizarro-Delgado, J1
Giménez-Gómez, P1
Merlos, Á1
Terés, L1
Serra-Graells, F1
Jiménez-Jorquera, C1
Domínguez, C1
Muñoz-Berbel, X1
Nna, VU1
Abu Bakar, AB1
Ahmad, A1
Mohamed, M1
Regan, JA1
Golubski, B1
Gilbert, EB1
Sullivan, B1
McCall, SJ1
Sata, SS1
Graham, JG1
Zhang, X1
Goodman, A1
Pothoven, K1
Houlihan, J1
Wang, S1
Gower, RM1
Luo, X1
Shea, LD1
De Feyter, HM1
Mason, GF1
Shulman, GI2
Rothman, DL1
Petersen, KF1
Prasad, S1
Xu, D1
Miller, SD1
Henderson, GC1
Ang, M1
Meyer, C1
Brendel, MD1
Bretzel, RG1
Linn, T1
Ciechanowska, A2
Ladyzynski, P2
Wojcicki, JM2
Sabalinska, S2
Krzymien, J2
Pulawska, E2
Karnafel, W2
Foltynski, P2
Kawiak, J2
Campbell, MD1
West, DJ1
Kingsley, MI1
Foley, P1
Kilduff, L1
Turner, D1
Gray, B1
Stephens, JW1
Patterson, E1
Marques, TM1
O'Sullivan, O1
Fitzgerald, P1
Fitzgerald, GF1
Cotter, PD1
Dinan, TG1
Cryan, JF1
Stanton, C1
Ross, RP1
Lewis, JS2
Dolgova, NV1
Zhang, Y1
Xia, CQ1
Wasserfall, CH2
Atkinson, MA2
Clare-Salzler, MJ1
Keselowsky, BG2
Yoon, YM1
Carstens, MR1
Campbell-Thompson, M1
Obermayer-Pietsch, B1
Bally, L1
Zueger, T1
Buehler, T1
Dokumaci, AS1
Speck, C1
Pasi, N1
Ciller, C1
Paganini, D1
Feller, K1
Loher, H1
Rosset, R1
Wilhelm, M1
Tappy, L1
Boesch, C1
Stettler, C1
Shetty, VB1
Fournier, PA5
Davey, RJ1
Retterath, AJ1
Paramalingam, N1
Roby, HC1
Cooper, MN1
Davis, EA1
Jones, TW5
Winnick, JJ1
Kraft, G1
Gregory, JM1
Edgerton, DS1
Williams, P1
Hajizadeh, IA1
Kamal, MZ1
Smith, M1
Farmer, B1
Scott, M1
Neal, D1
Donahue, EP1
Allen, E1
Cherrington, AD1
de Oliveira, LR1
Martins, C1
Fidalgo, TK1
Freitas-Fernandes, LB1
de Oliveira Torres, R1
Soares, AL1
Almeida, FC1
Valente, AP1
de Souza, IP1
Wang, Y1
Deng, GG1
Davies, KP1
Comar, JF1
de Oliveira, DS1
Bracht, L1
Kemmelmeier, FS1
Peralta, RM1
Bracht, A1
Mader, JK1
Messerschmidt, J1
Ratter, JM1
Hijmans, AG1
Netea, MG1
Stienstra, R1
Verbeke, CS1
Gordo, S1
Schubert, DA1
Lewin, SA1
Desai, RM1
Dobbins, J1
Wucherpfennig, KW1
Mooney, DJ1
Madea, B1
Fromont, I1
Nicoli, F1
Valéro, R1
Felician, O1
Lebail, B1
Lefur, Y1
Mancini, J1
Paquis-Flucklinger, V1
Cozzone, PJ1
Vialettes, B1
Barba, I1
Garcia-Ramírez, M1
Hernández, C1
Alonso, MA1
Masmiquel, L1
García-Dorado, D1
Simó, R1
Petriczko, E1
Horodnicka-Jozwa, A1
Grabowska-Wnuk, W1
Sienko, M1
Syrenicz, A1
Walczak, M1
Maran, A2
Pavan, P2
Bonsembiante, B1
Brugin, E1
Ermolao, A1
Avogaro, A5
Zaccaria, M1
Evangeliou, A1
Gourgiotis, D1
Karagianni, C1
Markouri, M1
Anogianaki, N1
Mamoulakis, D1
Maropoulos, G1
Tsakalidis, C1
Frentzayias, A1
Nicolaidou, P1
Wetter, J1
Gohlke, BC1
Woelfle, JF1
Han, Y1
Zeng, Q1
E, L1
Wang, D1
He, H1
Liu, H1
Adolfsson, P1
Nilsson, S1
Albertsson-Wikland, K1
Lindblad, B1
Galassetti, P2
Tate, D2
Neill, RA2
Morrey, S1
Davis, SN2
Jacob, RJ1
Fan, X1
Evans, ML1
Dziura, J1
Sherwin, RS3
Enoksson, S1
Caprio, SK1
Rife, F2
Tamborlane, WV2
Linke, A1
Zhao, G1
Recchia, FA1
Williams, J1
Xu, X1
Hintze, TH1
Sarto, P1
Merlo, L1
Casara, D1
Ponchia, A1
Biasin, R1
Noventa, D1
Unal, M1
Unal, DO1
Salman, F1
Baltaci, AK1
Mogulkoc, R1
Guelfi, KJ3
Sailaja Devi, MM1
Das, UN2
Richardson, A1
Leu, SY1
Suresh, Y1
Kawashima, Y1
Herrero, P1
Peterson, LR1
McGill, JB1
Matthew, S1
Lesniak, D1
Dence, C1
Gropler, RJ1
Bussau, VA1
Ferreira, LD1
Sasano, N1
Fujita, Y1
So, M1
Sobue, K1
Sasano, H1
Katsuya, H1
Ratnam, N1
Smythe, GA1
Horvath, K1
Bock, G1
Regittnig, W1
Bodenlenz, M1
Wutte, A1
Plank, J1
Magnes, C1
Sinner, F1
Fürst-Recktenwald, S1
Theobald, K1
Mäkinen, VP1
Soininen, P1
Forsblom, C1
Parkkonen, M1
Ingman, P1
Kaski, K1
Groop, PH1
Ala-Korpela, M1
Lager, I1
Ostman, J1
Husband, DJ1
Marshall, SM1
Walford, S2
Hanning, I2
Wright, PD1
Alberti, KG5
Capaldo, B1
Home, PD2
Massi-Benedetti, M1
Worth, R1
Cook, DB1
Heaton, A1
Gooch, BR1
Abumrad, NN1
Robinson, RP1
Crofford, OB1
Albanese, B1
Manescalchi, PG1
Pasquini, G1
Morini, R1
Marsilii, A1
Saratti, A1
Botta, RM1
Sinagra, D1
Migliore, MG1
Verga, S1
Dagogo-Jack, S1
Rattarasarn, C1
Cryer, PE2
Yasar, SA1
Tulassay, T1
Madácsy, L1
Körner, A1
Szücs, L1
Nagy, I1
Szabó, A1
Miltényi, M1
McLellan, AC2
Thornalley, PJ2
Benn, J1
Sonksen, PH2
Gnudi, L1
Valerio, A2
Miola, M1
Opportuno, A1
Tiengo, A2
Bier, DM1
Ramires, PR1
Forjaz, CL1
Silva, ME1
Diament, J1
Nicolau, W1
Liberman, B1
Negrão, CE1
Pampanelli, S2
Fanelli, C2
Lalli, C2
Ciofetta, M2
Sindaco, PD1
Lepore, M2
Modarelli, F1
Rambotti, AM1
Epifano, L1
Di Vincenzo, A2
Bartocci, L1
Annibale, B1
Brunetti, P2
Bolli, GB2
Colburn, WA1
Gottlieb, AB1
Koda, J1
Kolterman, OG1
Ahlborg, G1
Lundberg, JM1
Del Sindaco, P1
Porcellati, F1
Bottini, P1
Page, T1
Bailey, CJ1
Bowen, J1
Richards, T1
Maravilla, K1
King, P2
Kong, MF2
Parkin, H2
MacDonald, IA2
Barber, C1
Tattersall, RB2
Sigal, RJ1
Fisher, SJ2
Halter, JB1
Vranic, M2
Marliss, EB1
Papas, KK1
Long, RC1
Sambanis, A1
Constantinidis, I1
McGowan, PE1
Lawrie, WC1
Reglinski, J1
Spickett, CM1
Wilson, R1
Walker, JJ1
Wisdom, S1
Maclean, MA1
Bar-Or, O1
Gerstein, HC1
Heigenhauser, GJ1
Shi, ZQ1
Lickley, HL1
Efendic, S1
Giacca, A1
Multari, G1
Werner, B1
Cervoni, M1
Lubrano, R1
Costantino, F1
Demiraj, V1
Terekhina, NA1
Nenasheva, OIu1
Akimov, PA1
Kalhan, SC1
Parimi, P1
Van Beek, R1
Gilfillan, C1
Saker, F1
Gruca, L1
Sauer, PJ1
Russell, RR1
Chyun, D1
Song, S1
Lee, FA1
Pfeifer, MA1
Wackers, FJ1
Young, LH1
Zuppi, C1
Messana, I1
Tapanainen, P1
Knip, M1
Vincenzoni, F1
Giardina, B1
Nuutinen, M1
Bischof, MG1
Bernroider, E1
Ludwig, C1
Kurzemann, S1
Kletter, K1
Waldhäusl, W1
Roden, M1
Adrogué, HJ1
Phillips, SA1
Marchenko, LF1
Baturin, AA1
Terent'eva, EA1
Miceli, MV1
Newsome, DA1
Rönnemaa, T1
Marniemi, J1
Leino, A1
Karanko, H1
Puukka, P1
Koivisto, VA1
Hale, PJ2
Nattrass, M4
Blagosklonnaia, IaV1
Krasil'nikova, EI1
Zaĭed, N1
Babenko, AIu1
Møller, N1
Jørgensen, JO1
Møller, J1
Bak, JF1
Pørksen, N1
Schmitz, O2
Akanji, AO1
Humphreys, S1
Thursfield, V1
Hockaday, TD1
Benn, JJ1
Bozzard, SJ1
Kelley, D1
Mitrakou, A1
Aoki, T1
Sorensen, J1
Gerich, J1
Hübinger, A1
Ridderskamp, I1
Lehmann, E1
Gries, FA1
Björkman, O1
Gunnarsson, R1
Hagström, E1
Felig, P1
Wahren, J1
Benzer, W1
Mähr, G1
Jensen, T1
Richter, EA1
Feldt-Rasmussen, B1
Kelbaek, H1
Deckert, T1
Rontoyannis, GP1
Ruddy, TD1
Shumak, SL1
Liu, PP1
Barnie, A1
Seawright, SJ1
McLaughlin, PR1
Zinman, B1
Delamater, AM1
Bubb, J1
Kurtz, SM1
Kuntze, J1
Smith, JA1
White, NH1
Santiago, JV1
Vaughan, NJ1
Rao, RH1
Kurtz, AB1
Buckell, HM1
Spathis, GS1
Pedersen, O1
Hjøllund, E1
Beck-Nielsen, H1
Richelsen, B1
Sørensen, NS1
Black, E1
Trevisan, R2
Nosadini, R2
Lippe, G1
Duner, E2
Fioretto, P2
Deana, R1
Tessari, P1
Velussi, M2
Hocking, MD2
Crase, J1
Rayner, PH2
Goicolea, I1
Rueda, M1
Hernández, I1
Quiroga, A1
Vázquez, JA1
Hermansen, K1
Møller, A1
Christensen, CK1
Christiansen, JS1
Orskov, H1
Mogensen, CE1
Iori, E1
Doria, A1
Merkel, C1
Berk, MA1
Clutter, WE1
Skor, D1
Shah, SD1
Gingerich, RP1
Parvin, CA1
Jimenez, JT1
Gräfenstein, K1
Duchna, W1

Clinical Trials (17)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Lactate Administration on Cerebral Blood Flow During Hypoglycemia; Are the Suppressive Effects of Lactate on Counterregulatory Responses to Hypoglycemia Reflected in an Altered CBF Response?[NCT03730909]10 participants (Anticipated)Interventional2018-06-11Recruiting
cArdiopulmonary exerCise Test Assessing Multiple bIOmarkers iN Type 1 Diabetes[NCT05097339]21 participants (Actual)Observational [Patient Registry]2019-05-10Completed
Exercise and Blood Glucose Levels in Patients With Type I Diabetes - a Pilot Study[NCT02075567]7 participants (Actual)Interventional2014-01-31Completed
A Trial Comparing the Effect of Exercise on Blood Glucose Between Insulin Degludec and Insulin Glargine in Subjects With Type 1 Diabetes[NCT01704417]Phase 140 participants (Actual)Interventional2012-10-31Completed
The Effect of Exercise-induced Hyperlacticacidemia on Counterregulatory Responses, Symptoms, Cognitive Function and Brain Lactate Accumulation During Hypoglycemia in (Hypoglycemic Unaware)Type I Diabetes Patients and Normal Controls[NCT02308293]30 participants (Actual)Interventional2015-01-31Completed
The Effect of Intravenous Lactate Administration on Brain Lactate Concentrations and pH During Euglycemia and Hypoglycemia in Patients With Type 1 Diabetes With and Without Impaired Awareness of Hypoglycemia[NCT03286816]19 participants (Actual)Interventional2016-11-30Completed
The Effect of Insulin-induced Hypoglycemia on Brain Lactate Accumulation and Regional Cerebral Blood Flow in Patients With Type 1 Diabetes Mellitus With and Without Hypoglycemia Unawareness and Non-diabetic Controls[NCT02146404]21 participants (Actual)Interventional2014-08-31Completed
Metabolic Studies in Type 1 Diabetic Patients After Allogenic Intraportal Islet Transplantation.[NCT01668485]Phase 436 participants (Actual)Interventional2001-11-30Completed
Comparison of CGM in Randomised Study of Real-time and Intermittently-scanned Systems in T1D With Normal Awareness of Hypoglycemia (CORRIDA)[NCT04358263]60 participants (Actual)Interventional2018-09-01Active, not recruiting
Exercise-related Fuel Metabolism and Glucose Stability in Individuals With Type 1 Diabetes Mellitus[NCT02068638]27 participants (Actual)Interventional2014-02-28Completed
Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes[NCT05478707]Phase 264 participants (Anticipated)Interventional2023-10-05Recruiting
Prevention of Hypoglycemia After Exercise Using DreaMed Substance Administration Device in Children and Adolescents With Type 1 Diabetes (The PHYSI-DREAM Study)[NCT02657083]20 participants (Actual)Interventional2016-01-31Completed
Day and Night Closed-Loop Glycemic Control With Faster-Acting Insulin Aspart in Young Adults With Type 1 Diabetes Using DreaMed Glucositter - The Fast PHYSI-DREAM Study[NCT03212950]20 participants (Actual)Interventional2017-07-10Completed
Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation? The TERRIFIC Study[NCT02897739]77 participants (Actual)Observational [Patient Registry]2015-08-31Completed
Lipid Biomarkers for Diabetic Heart Disease[NCT01752842]70 participants (Actual)Interventional2013-03-31Completed
The Effects of Basal Insulin Suspension at the Start of Exercise on Blood Glucose Levels During Continuous vs. Circuit-based Exercise in Individuals With Type 1 Diabetes on CSII[NCT03034798]12 participants (Actual)Observational2015-01-14Completed
Propranolol as a Treatment for Impaired Awareness of Hypoglycemia in Type 1 Diabetes[NCT03161964]Phase 22 participants (Actual)Interventional2017-10-19Terminated (stopped due to Statistical power could not be achieved due to low enrollment.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in C24:0/C16:0 Ceramide Ratio

Mass spectrometry-based quantification of the ratio of C24:0 ceramide to C16:0 ceramide in plasma. (NCT01752842)
Timeframe: Baseline and 12 weeks

Interventionratio (Mean)
Fenofibrate-1.6
Placebo for Fenofibrate-0.03

Change in Cardiac Diastolic Function as Measured by E' (cm/s)

Change was measured by echocardiography and was calculated as the value at 12 weeks minus the value at baseline. (NCT01752842)
Timeframe: Baseline and 12 weeks

Interventioncm/s (Mean)
Fenofibrate-0.02
Placebo for Fenofibrate0.55

Change in Cardiac Systolic Function as Measured by Fractional Shortening Percent

Change was measured by echocardiography and was calculated as the value at 12 weeks minus the value at baseline. (NCT01752842)
Timeframe: Baseline and 12 weeks

Interventionpercent (Mean)
Fenofibrate0.025
Placebo for Fenofibrate0.030

Reviews

5 reviews available for lactic acid and Autoimmune Diabetes

ArticleYear
Tolerance strategies employing antigen-coupled apoptotic cells and carboxylated PLG nanoparticles for the treatment of type 1 diabetes.
    The review of diabetic studies : RDS, 2012,Winter, Volume: 9, Issue:4

    Topics: Animals; Apoptosis; Autoantigens; Diabetes Mellitus, Type 1; Disease Models, Animal; Humans; Immune

2012
Sudden death, especially in infancy--improvement of diagnoses by biochemistry, immunohistochemistry and molecular pathology.
    Legal medicine (Tokyo, Japan), 2009, Volume: 11 Suppl 1

    Topics: Adult; Blood Chemical Analysis; Child; Death, Sudden; Diabetes Mellitus, Type 1; DNA, Viral; Forensi

2009
[Insulin delivery by using PLGA nanoparticulate system].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 1; Drug Carriers; Insulin; Lactic Acid; Nanostructures; Polyglycoli

2006
beta-adrenergic blockade and diabetes mellitus. A review.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D

1983
Glucose homeostasis and the kidney.
    Kidney international, 1992, Volume: 42, Issue:5

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucose; Glycogen;

1992

Trials

21 trials available for lactic acid and Autoimmune Diabetes

ArticleYear
A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients With Type 1 Diabetes.
    Diabetes, 2017, Volume: 66, Issue:7

    Topics: Adult; Awareness; Case-Control Studies; Catecholamines; Cognitive Dysfunction; Cross-Over Studies; D

2017
Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study.
    Diabetes technology & therapeutics, 2017, Volume: 19, Issue:6

    Topics: Adult; Biomarkers; Blood Glucose; Combined Modality Therapy; Cross-Over Studies; Diabetes Mellitus,

2017
Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes.
    Diabetologia, 2014, Volume: 57, Issue:3

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Gluconeogenesis; Glucose; Glucose Clamp Tec

2014
Simulated games activity vs continuous running exercise: a novel comparison of the glycemic and metabolic responses in T1DM patients.
    Scandinavian journal of medicine & science in sports, 2015, Volume: 25, Issue:2

    Topics: Adult; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Therapy; Female; Games, Recrea

2015
Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Homeostasis; Hormones; Humans; Insulin, L

2015
Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Homeostasis; Hormones; Humans; Insulin, L

2015
Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Homeostasis; Hormones; Humans; Insulin, L

2015
Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Homeostasis; Hormones; Humans; Insulin, L

2015
Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.
    Diabetologia, 2016, Volume: 59, Issue:4

    Topics: Adult; Blood Glucose; Catecholamines; Cross-Over Studies; Diabetes Mellitus, Type 1; Energy Metaboli

2016
Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.
    Diabetologia, 2016, Volume: 59, Issue:4

    Topics: Adult; Blood Glucose; Catecholamines; Cross-Over Studies; Diabetes Mellitus, Type 1; Energy Metaboli

2016
Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.
    Diabetologia, 2016, Volume: 59, Issue:4

    Topics: Adult; Blood Glucose; Catecholamines; Cross-Over Studies; Diabetes Mellitus, Type 1; Energy Metaboli

2016
Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.
    Diabetologia, 2016, Volume: 59, Issue:4

    Topics: Adult; Blood Glucose; Catecholamines; Cross-Over Studies; Diabetes Mellitus, Type 1; Energy Metaboli

2016
Accuracy of Continuous Glucose Monitoring (CGM) during Continuous and High-Intensity Interval Exercise in Patients with Type 1 Diabetes Mellitus.
    Nutrients, 2016, Aug-10, Volume: 8, Issue:8

    Topics: Adult; Bicycling; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 1; Diet, Diabeti

2016
Continuous glucose monitoring reveals delayed nocturnal hypoglycemia after intermittent high-intensity exercise in nontrained patients with type 1 diabetes.
    Diabetes technology & therapeutics, 2010, Volume: 12, Issue:10

    Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; He

2010
The relation between serum leptin levels and max VO2 in male patients with type I diabetes and healthy sedentary males.
    Endocrine research, 2004, Volume: 30, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Humans; Lactic Acid; Leptin; Male; Ox

2004
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Fatty Acids, Nonesteri

2005
Effect of differing antecedent hypoglycemia on counterregulatory responses to exercise in type 1 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty Acids, Nonesterified;

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F

2006
Effect of intermittent high-intensity compared with continuous moderate exercise on glucose production and utilization in individuals with type 1 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Female; Glucose; Glucose Clam

2007
Effect of intermittent high-intensity compared with continuous moderate exercise on glucose production and utilization in individuals with type 1 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Female; Glucose; Glucose Clam

2007
Effect of intermittent high-intensity compared with continuous moderate exercise on glucose production and utilization in individuals with type 1 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Female; Glucose; Glucose Clam

2007
Effect of intermittent high-intensity compared with continuous moderate exercise on glucose production and utilization in individuals with type 1 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Female; Glucose; Glucose Clam

2007
Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study.
    Diabetes, obesity & metabolism, 2008, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind

2008
Microdialysis technique as a monitoring system for acute complications of diabetes.
    Artificial organs, 2008, Volume: 32, Issue:1

    Topics: Abdominal Fat; Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2;

2008
Continuous intraperitoneal insulin infusion in the management of severely brittle diabetes--a metabolic and clinical comparison with intravenous infusion.
    Diabetic medicine : a journal of the British Diabetic Association, 1984, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Female; Human

1984
Pharmacokinetics and pharmacodynamics of AC137 (25,28,29 tripro-amylin, human) after intravenous bolus and infusion doses in patients with insulin-dependent diabetes.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:1

    Topics: Adult; Amyloid; Blood Glucose; Calcium; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug;

1996
Exercise-induced changes in neuropeptide Y, noradrenaline and endothelin-1 levels in young people with type I diabetes.
    Clinical physiology (Oxford, England), 1996, Volume: 16, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Endothelin-1; Energy Metabolism; Exercise; Exercise

1996
Intravenous lactate prevents cerebral dysfunction during hypoglycaemia in insulin-dependent diabetes mellitus.
    Clinical science (London, England : 1979), 1998, Volume: 94, Issue:2

    Topics: Adult; Analysis of Variance; Brain; Diabetes Mellitus, Type 1; Epinephrine; Evoked Potentials, Audit

1998
Metabolic response to different forms of physical exercise in type I diabetics and the duration of the glucose lowering effect.
    European journal of clinical investigation, 1985, Volume: 15, Issue:4

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Hormones; Humans; Lactates; Lactic Acid; Ma

1985
Diurnal plasma profiles of metabolite and hormone concentration in insulin-dependent diabetic patients during conventional insulin treatment and continuous subcutaneous insulin infusion. A controlled study.
    Acta endocrinologica, 1987, Volume: 114, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Gl

1987

Other Studies

104 other studies available for lactic acid and Autoimmune Diabetes

ArticleYear
Assessment of changes in blood lactate levels in children and adolescents with type 1 diabetes during a football tournament (GoalDiab Study).
    Pediatric endocrinology, diabetes, and metabolism, 2021, Volume: 27, Issue:4

    Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Exercise; Football; Humans; Insulin Infusion Systems;

2021
Effect of lactate administration on cerebral blood flow during hypoglycemia in people with type 1 diabetes.
    BMJ open diabetes research & care, 2022, Volume: 10, Issue:2

    Topics: Cerebrovascular Circulation; Diabetes Mellitus, Type 1; Glucose Clamp Technique; Humans; Hypoglycemi

2022
Trends of glucose, lactate and ketones during anaerobic and aerobic exercise in subjects with type 1 diabetes: The ACTION-1 study.
    Diabetes/metabolism research and reviews, 2022, Volume: 38, Issue:6

    Topics: Adult; Anaerobiosis; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Exerci

2022
Addressing Cognitive Biases in Interpreting an Elevated Lactate in a Patient with Type 1 Diabetes and Thiamine Deficiency.
    Journal of general internal medicine, 2023, Volume: 38, Issue:6

    Topics: Beriberi; Bias; Cognition; COVID-19; Diabetes Mellitus, Type 1; Female; Humans; Lactic Acid; Pandemi

2023
Quantifying insulin-mediated and noninsulin-mediated changes in glucose dynamics during resistance exercise in type 1 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2023, 09-01, Volume: 325, Issue:3

    Topics: Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Glucose; Humans; Hypoglycemia; Insulin; Lactic A

2023
Soluble Receptor for Glycation End-products Concentration Increases Following the Treatment of Severe Diabetic Ketoacidosis
    Journal of clinical research in pediatric endocrinology, 2020, 06-03, Volume: 12, Issue:2

    Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glycation End Products,

2020
Development of Electrochemical Methods to Enzymatically Detect Lactate and Glucose Using Imaginary Impedance for Enhanced Management of Glycemic Compromised Patients.
    Critical reviews in biomedical engineering, 2019, Volume: 47, Issue:3

    Topics: Algorithms; Biomarkers; Biosensing Techniques; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2;

2019
[Changes of lactate levels in diabetic ketoacidosis and in newly diagnosed type 1 diabetes mellitus].
    Orvosi hetilap, 2019, Volume: 160, Issue:45

    Topics: Blood Gas Analysis; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Femal

2019
Total Pancreatectomy and Pancreatic Allotransplant in a Porcine Experimental Model.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2020, Volume: 18, Issue:3

    Topics: Animals; Biomarkers; Blood Glucose; Blood Platelets; C-Peptide; Diabetes Mellitus, Type 1; Disease M

2020
Blood Glucose Responses during Cardiopulmonary Incremental Exercise Testing in Type 1 Diabetes: A Pooled Analysis.
    Medicine and science in sports and exercise, 2021, 06-01, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Anaerobic Threshold; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Tes

2021
Blood Glucose Responses during Cardiopulmonary Incremental Exercise Testing in Type 1 Diabetes: A Pooled Analysis.
    Medicine and science in sports and exercise, 2021, 06-01, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Anaerobic Threshold; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Tes

2021
Blood Glucose Responses during Cardiopulmonary Incremental Exercise Testing in Type 1 Diabetes: A Pooled Analysis.
    Medicine and science in sports and exercise, 2021, 06-01, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Anaerobic Threshold; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Tes

2021
Blood Glucose Responses during Cardiopulmonary Incremental Exercise Testing in Type 1 Diabetes: A Pooled Analysis.
    Medicine and science in sports and exercise, 2021, 06-01, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Anaerobic Threshold; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Tes

2021
Predictors of the maximal oxygen consumption in adult patients with type 1 diabetes treated with personal insulin pumps.
    Journal of diabetes investigation, 2021, Volume: 12, Issue:8

    Topics: Adiposity; Adult; Anaerobic Threshold; Blood Glucose; Blood Glucose Self-Monitoring; Cohort Studies;

2021
Long, Noncoding RNA SRA Induces Apoptosis of β-Cells by Promoting the IRAK1/LDHA/Lactate Pathway.
    International journal of molecular sciences, 2021, Feb-09, Volume: 22, Issue:4

    Topics: Adolescent; Antagomirs; Apoptosis; Carrier Proteins; Cell Line; Diabetes Mellitus, Type 1; Feedback,

2021
Atypical blood glucose response to continuous and interval exercise in a person with type 1 diabetes: a case report.
    Journal of medical case reports, 2017, Jun-30, Volume: 11, Issue:1

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Exercise Test; Gl

2017
An effective treatment approach of DPP-IV inhibitor encapsulated polymeric nanoparticles conjugated with anti-CD-4 mAb for type 1 diabetes.
    Drug development and industrial pharmacy, 2018, Volume: 44, Issue:7

    Topics: Animals; Antibodies; CD4 Antigens; Cell Line, Tumor; Delayed-Action Preparations; Diabetes Mellitus,

2018
Prevention of autoimmune diabetes and islet allograft rejection by beta cell expression of XIAP: Insight into possible mechanisms of local immunomodulation.
    Molecular and cellular endocrinology, 2018, 12-05, Volume: 477

    Topics: Allografts; Animals; Diabetes Mellitus, Type 1; Glucose; Graft Rejection; Humans; Immune Tolerance;

2018
Assessment of Safety and Glycemic Control During Football Tournament in Children and Adolescents With Type 1 Diabetes-Results of GoalDiab Study.
    Pediatric exercise science, 2019, 11-01, Volume: 31, Issue:4

    Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Humans; Hypoglycemia; Hypoglyce

2019
Reconfigurable multiplexed point of Care System for monitoring type 1 diabetes patients.
    Biosensors & bioelectronics, 2019, Jul-01, Volume: 136

    Topics: Alginates; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Humans; Hydrogel, Polyethylene Glycol

2019
Metformin mitigates impaired testicular lactate transport/utilisation and improves sexual behaviour in streptozotocin-induced diabetic rats.
    Archives of physiology and biochemistry, 2021, Volume: 127, Issue:1

    Topics: Animals; Biological Transport; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose T

2021
Glycogenic Hepatopathy Causing Elevated Lactic Acid and Liver Enzymes.
    The American journal of medicine, 2020, Volume: 133, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Glucose; Diabetes Mel

2020
PLG scaffold delivered antigen-specific regulatory T cells induce systemic tolerance in autoimmune diabetes.
    Tissue engineering. Part A, 2013, Volume: 19, Issue:11-12

    Topics: Adoptive Transfer; Animals; Antigens; Dendritic Cells; Diabetes Mellitus, Type 1; Female; Graft Surv

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction

2013
The diabetic brain during hypoglycemia: in the midst of plenty of lactate.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid

2013
Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis.
    The International journal of artificial organs, 2013, Volume: 36, Issue:12

    Topics: Adipose Tissue; Adult; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus

2013
Streptozotocin-induced type-1-diabetes disease onset in Sprague-Dawley rats is associated with an altered intestinal microbiota composition and decreased diversity.
    Microbiology (Reading, England), 2015, Volume: 161, Issue:Pt 1

    Topics: Animals; Antibiotics, Antineoplastic; Biodiversity; Diabetes Mellitus, Experimental; Diabetes Mellit

2015
A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice.
    Clinical immunology (Orlando, Fla.), 2015, Volume: 160, Issue:1

    Topics: Animals; CD4-Positive T-Lymphocytes; Cells, Cultured; Cholecalciferol; Dendritic Cells; Diabetes Mel

2015
A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice.
    Scientific reports, 2015, Aug-17, Volume: 5

    Topics: Adjuvants, Immunologic; Animals; Blood Glucose; Bone Marrow Cells; Cell Movement; Cells, Cultured; D

2015
Effect of Exercise Intensity on Glucose Requirements to Maintain Euglycemia During Exercise in Type 1 Diabetes.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diet; Exercise; Female; Glucose; Glucos

2016
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
    Diabetes, 2016, Volume: 65, Issue:6

    Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech

2016
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
    Diabetes, 2016, Volume: 65, Issue:6

    Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech

2016
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
    Diabetes, 2016, Volume: 65, Issue:6

    Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech

2016
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
    Diabetes, 2016, Volume: 65, Issue:6

    Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech

2016
Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.
    The Journal of clinical investigation, 2016, 06-01, Volume: 126, Issue:6

    Topics: Animals; Blood Glucose; Brain; Diabetes Mellitus, Type 1; Disease Models, Animal; Dogs; Female; Fruc

2016
Salivary Metabolite Fingerprint of Type 1 Diabetes in Young Children.
    Journal of proteome research, 2016, 08-05, Volume: 15, Issue:8

    Topics: Acetates; Case-Control Studies; Child, Preschool; Diabetes Mellitus, Type 1; Discriminant Analysis;

2016
Novel insights into development of diabetic bladder disorder provided by metabolomic analysis of the rat nondiabetic and diabetic detrusor and urothelial layer.
    American journal of physiology. Endocrinology and metabolism, 2016, 08-01, Volume: 311, Issue:2

    Topics: Amino Acids, Branched-Chain; Animals; Bile Acids and Salts; Case-Control Studies; Citric Acid Cycle;

2016
The Metabolic Responses to L-Glutamine of Livers from Rats with Diabetes Types 1 and 2.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Alanine; Ammonia; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gluconeogenesis; Gl

2016
Proinflammatory Effects of Hypoglycemia in Humans With or Without Diabetes.
    Diabetes, 2017, Volume: 66, Issue:4

    Topics: Adult; Awareness; Case-Control Studies; Chemokine CCL2; Cytokines; Diabetes Mellitus, Type 1; Epinep

2017
Multicomponent Injectable Hydrogels for Antigen-Specific Tolerogenic Immune Modulation.
    Advanced healthcare materials, 2017, Volume: 6, Issue:6

    Topics: Animals; Antigens; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hydrogels; Immune Tol

2017
Brain anomalies in maternally inherited diabetes and deafness syndrome.
    Journal of neurology, 2009, Volume: 256, Issue:10

    Topics: Adult; Aged; Brain; Cerebellar Ataxia; Cognition Disorders; Deafness; Diabetes Mellitus; Diabetes Me

2009
Metabolic fingerprints of proliferative diabetic retinopathy: an 1H-NMR-based metabonomic approach using vitreous humor.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:9

    Topics: Adult; Ascorbic Acid; Carbon Isotopes; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Gala

2010
Interstitial measurements of glucose, glycerol and lactate in adolescents with decompensated type 1 diabetes.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:4

    Topics: Adipose Tissue; Adolescent; Diabetes Mellitus, Type 1; Female; Glucose; Glycerol; Humans; Lactic Aci

2010
Carnitine status and lactate increase in patients with type I juvenile diabetes.
    Minerva pediatrica, 2010, Volume: 62, Issue:6

    Topics: Adolescent; Carnitine; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Humans; Lactic Ac

2010
Hyperglycemic hyperosmolar state as initial manifestation of pediatric insulin-dependent diabetes.
    Klinische Padiatrie, 2012, Volume: 224, Issue:1

    Topics: Autoantibodies; Blood Glucose; Child, Preschool; Combined Modality Therapy; Creatine; Diabetes Melli

2012
Sustained topical delivery of insulin from fibrin gel loaded with poly(lactic-co-glycolic Acid) microspheres improves the biomechanical retention of titanium implants in type 1 diabetic rats.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2012, Volume: 70, Issue:10

    Topics: Administration, Topical; Animals; Biomechanical Phenomena; Delayed-Action Preparations; Dental Impla

2012
Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls.
    Pediatric diabetes, 2012, Volume: 13, Issue:8

    Topics: Adolescent; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exerci

2012
Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls.
    Pediatric diabetes, 2012, Volume: 13, Issue:8

    Topics: Adolescent; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exerci

2012
Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls.
    Pediatric diabetes, 2012, Volume: 13, Issue:8

    Topics: Adolescent; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exerci

2012
Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls.
    Pediatric diabetes, 2012, Volume: 13, Issue:8

    Topics: Adolescent; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exerci

2012
Effect of gender on counterregulatory responses to euglycemic exercise in type 1 diabetes.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11

    Topics: Adult; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty

2002
Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:12

    Topics: 3-Hydroxybutyric Acid; Acute Disease; Adaptation, Physiological; Animals; Blood-Brain Barrier; Brain

2002
Defective activation of skeletal muscle and adipose tissue lipolysis in type 1 diabetes mellitus during hypoglycemia.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:4

    Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephri

2003
Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:3

    Topics: 3-Hydroxybutyric Acid; Alloxan; Animals; Blood Glucose; Blood Pressure; Body Weight; Carbon Dioxide;

2003
Metabolic and cardiovascular parameters in type 1 diabetes at extreme altitude.
    Medicine and science in sports and exercise, 2004, Volume: 36, Issue:8

    Topics: Adult; Altitude; Blood Cell Count; Blood Gas Analysis; Blood Glucose; Cardiovascular System; Case-Co

2004
Intermittent high-intensity exercise does not increase the risk of early postexercise hypoglycemia in individuals with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Humans; Hypoglycemia; Insulin

2005
Effect of prostaglandins against alloxan-induced diabetes mellitus.
    Prostaglandins, leukotrienes, and essential fatty acids, 2006, Volume: 74, Issue:1

    Topics: Alloxan; Alprostadil; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Ceruloplasmin; Di

2006
Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus.
    Prostaglandins, leukotrienes, and essential fatty acids, 2006, Volume: 74, Issue:3

    Topics: Alloxan; Animals; Arachidonic Acid; Blood Glucose; Body Weight; Catalase; Ceruloplasmin; Diabetes Me

2006
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus.
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Adult; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 1; Fatty Acids; Female; Glucose;

2006
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus.
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Adult; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 1; Fatty Acids; Female; Glucose;

2006
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus.
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Adult; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 1; Fatty Acids; Female; Glucose;

2006
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus.
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Adult; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 1; Fatty Acids; Female; Glucose;

2006
Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Amides; Anesthesia; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Blood Gas An

2007
1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death.
    Molecular systems biology, 2008, Volume: 4

    Topics: Acetates; Adult; Albuminuria; Antihypertensive Agents; Apolipoproteins B; Biomarkers; Cholesterol; C

2008
Adrenergic blockade and hypoglycaemia.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucag

1983
The response of blood intermediary metabolite levels to 24 hours treatment with a blood glucose-controlled insulin infusion system in type 1 diabetes.
    Diabetes research (Edinburgh, Scotland), 1984, Volume: 1, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glycerol; H

1984
Near normalization of metabolism of IDDM: comparison of continuous subcutaneous (CSII) versus intraperitoneal (CIPII) insulin delivery.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16 Suppl 1

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Humans; Injecti

1984
[Hemorrheological changes induced by submaximal exertion in subjects with insulin-dependent diabetes mellitus].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Adolescent; Adult; Blood; Blood Gas Analysis; Blood Glucose; Blood Viscosity; Diabetes Mellitus, Typ

1983
[Effects of acute ingestion of ethanol on several metabolic parameters (blood sugar, triglycerides, non-esterified fatty acids, lactic acid and uric acid) in subjects with type I diabetes mellitus].
    Bollettino della Societa italiana di biologia sperimentale, 1982, Aug-15, Volume: 58, Issue:15

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Ethanol; Fatty Acids, Nonesterified; Fe

1982
Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM.
    Diabetes, 1994, Volume: 43, Issue:12

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Awareness; Blood Glucose; Diabetes Mellitus, Type 1; Epine

1994
Sympathetic-adrenergic activity and acid-base regulation under acute physical stress in type I (insulin-dependent) diabetic children.
    Hormone research, 1994, Volume: 42, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Bicarbonates; Blood Glucose; Child; Diabetes Mellitus,

1994
Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications.
    Clinical science (London, England : 1979), 1994, Volume: 87, Issue:1

    Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathi

1994
Effects of different plasma glucose concentrations on lipolytic and ketogenic responsiveness to epinephrine in type I (insulin-dependent) diabetic subjects.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:4

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified;

1993
Exercise tolerance is lower in type I diabetics compared with normal young men.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:2

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Exercise Tolerance; Fatty Acids, Noneste

1993
Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia.
    Diabetologia, 1996, Volume: 39, Issue:6

    Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty

1996
Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation.
    Diabetes, 1997, Volume: 46, Issue:7

    Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1;

1997
Glucose-lowering effect of BTS 67 582.
    British journal of pharmacology, 1997, Volume: 122, Issue:7

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Guanidines; Hyperglycemia

1997
MR imaging and proton MR spectroscopy in A-to-G substitution at nucleotide position 3243 of leucine transfer RNA.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Adult; Amino Acid Substitution; Aspartic Acid; Basal Ganglia; Base Sequence; Brain; Cerebral Cortex;

1998
Well-being, cerebral function, and physical fatigue after nocturnal hypoglycemia in IDDM.
    Diabetes care, 1998, Volume: 21, Issue:3

    Topics: Activities of Daily Living; Adult; Affect; Blood Glucose; Brain; Catecholamines; Circadian Rhythm; D

1998
Glucoregulation during and after intense exercise: effects of beta-adrenergic blockade in subjects with type 1 diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:11

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrin

1999
Development of a bioartificial pancreas: II. Effects of oxygen on long-term entrapped betaTC3 cell cultures.
    Biotechnology and bioengineering, 1999, Volume: 66, Issue:4

    Topics: Animals; Biotechnology; Cell Line; Diabetes Mellitus, Type 1; Energy Metabolism; Glucose; Glycolysis

1999
1H NMR as a non-invasive probe of amniotic fluid in insulin dependent diabetes mellitus.
    Journal of perinatal medicine, 1999, Volume: 27, Issue:5

    Topics: Acetates; Alanine; Amniotic Fluid; Citric Acid; Diabetes Mellitus, Type 1; Female; Glucose; Humans;

1999
Perceived exertion with glucose ingestion in adolescent males with IDDM.
    Medicine and science in sports and exercise, 2000, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Blood Glucose; Body Weight; Case-Control Studies; Diabetes

2000
Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.
    The Journal of endocrinology, 2001, Volume: 168, Issue:1

    Topics: 3-Hydroxybutyric Acid; Alanine; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Typ

2001
Peritoneal dialysis in an infant with type 1 diabetes and hyperosmolar coma.
    Journal of endocrinological investigation, 2001, Volume: 24, Issue:2

    Topics: Acidosis, Lactic; Dehydration; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Humans; Hypergl

2001
[Novel methods in diabetes mellitus diagnosis].
    Klinicheskaia laboratornaia diagnostika, 2001, Issue:8

    Topics: Cadaver; Coma; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucose; Humans; Hyperglycemia;

2001
Estimation of gluconeogenesis in newborn infants.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:5

    Topics: Amino Acids; Blood Glucose; Body Water; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Femal

2001
Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:5

    Topics: Adult; Cardiac Output; Catecholamines; Chemical Precipitation; Diabetes Mellitus, Type 1; Diastole;

2001
Proton nuclear magnetic resonance spectral profiles of urine from children and adolescents with type 1 diabetes.
    Clinical chemistry, 2002, Volume: 48, Issue:4

    Topics: Adolescent; Alanine; Child; Citric Acid; Diabetes Mellitus, Type 1; Female; Glycated Hemoglobin; Hip

2002
Effect of near physiologic insulin therapy on hypoglycemia counterregulation in type-1 diabetes.
    Hormone research, 2001, Volume: 56, Issue:5-6

    Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, None

2001
Fluorimetric assay of D-lactate.
    Analytical biochemistry, 1992, Volume: 206, Issue:1

    Topics: Calibration; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme Stability; Fluorometry; Hu

1992
[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
    Pediatriia, 1991, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Com

1991
Cultured retinal pigment epithelium cells from donors with type I diabetes show an altered insulin response.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:11

    Topics: Cell Division; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Endocytosis; Glucos

1991
Hormone response of diabetic patients to exercise at cool and warm temperatures.
    European journal of applied physiology and occupational physiology, 1991, Volume: 62, Issue:2

    Topics: Adult; Blood Glucose; Blood Pressure; Body Temperature; Cold Temperature; Diabetes Mellitus, Type 1;

1991
The short-term effect of nicotinic acid on intermediary metabolism in insulin-dependent diabetes mellitus.
    Annals of clinical biochemistry, 1991, Volume: 28 ( Pt 1)

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Humans; Insul

1991
[Effect of biguanides on the indicators of thrombelastography and the level of lactic acid in diabetes mellitus].
    Sovetskaia meditsina, 1990, Issue:12

    Topics: Adolescent; Adult; Aged; Biguanides; Blood Coagulation; Diabetes Mellitus, Type 1; Diabetes Mellitus

1990
Substrate metabolism during modest hyperinsulinemia in response to isolated hyperketonemia in insulin-dependent diabetic subjects.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:12

    Topics: 3-Hydroxybutyric Acid; Adult; Diabetes Mellitus, Type 1; Gluconeogenesis; Glucose; Glycerol; Hormone

1990
The relationship of plasma acetate with glucose and other blood intermediary metabolites in non-diabetic and diabetic subjects.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Oct-31, Volume: 185, Issue:1

    Topics: Acetates; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Fatty

1989
Persistent abnormalities of the metabolism of an oral glucose load in insulin-treated type I diabetics.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:11

    Topics: Administration, Oral; Alanine; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Fore

1989
Splanchnic and renal exchange of infused fructose in insulin-deficient type 1 diabetic patients and healthy controls.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:1

    Topics: Adult; Amino Acids; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Fructose; Gluconeogenesis

1989
[Characteristics of insulin and glucose regulation in short-term physical exertion and recovery in type I diabetic patients].
    Wiener medizinische Wochenschrift (1946), 1988, Jul-31, Volume: 138, Issue:14

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Humans; Insulin; Lactates; La

1988
Impaired aerobic work capacity in insulin dependent diabetics with increased urinary albumin excretion.
    British medical journal (Clinical research ed.), 1988, May-14, Volume: 296, Issue:6633

    Topics: Adolescent; Adult; Albuminuria; Diabetes Mellitus, Type 1; Female; Heart; Heart Rate; Humans; Lactat

1988
Lactate elimination from the blood during active recovery.
    The Journal of sports medicine and physical fitness, 1988, Volume: 28, Issue:2

    Topics: Adult; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; Female; Gluconeogenesis; Humans; Lact

1988
The relationship of cardiac diastolic dysfunction to concurrent hormonal and metabolic status in type I diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:1

    Topics: Adult; Blood Glucose; Cardiomyopathies; Diabetes Mellitus, Type 1; Diastole; Epinephrine; Female; Gl

1988
Physiologic responses to acute psychological stress in adolescents with type 1 diabetes mellitus.
    Journal of pediatric psychology, 1988, Volume: 13, Issue:1

    Topics: Adolescent; Blood Glucose; Cardiovascular System; Diabetes Mellitus, Type 1; Female; Glycated Hemogl

1988
Strict nocturnal diabetic control diminishes subsequent glycemic escape during acute insulin withdrawal.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Fatty Acids, Nonester

1986
Continuous subcutaneous insulin infusion fails to correct impaired basal glucose metabolism and impaired insulin sensitivity of adipocytes from patients with type 1 (insulin-dependent) diabetes.
    Diabetes research (Edinburgh, Scotland), 1986, Volume: 3, Issue:1

    Topics: Adipose Tissue; Adult; Biological Transport; Blood Glucose; Diabetes Mellitus, Type 1; Erythrocytes;

1986
Metabolic effects of low-dose incremental insulin infusion in diabetic man.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:2

    Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Huma

1986
Type I diabetes is characterized by insulin resistance not only with regard to glucose, but also to lipid and amino acid metabolism.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:6

    Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; C-Peptide; Diabetes Mellitus, Type 1; Female; Gluco

1986
Metabolic rhythms in adolescents with diabetes during treatment with porcine or human insulin.
    Archives of disease in childhood, 1986, Volume: 61, Issue:4

    Topics: Adolescent; Animals; Blood Glucose; Child; Diabetes Mellitus, Type 1; Drug Administration Schedule;

1986
[Effect of postprandial exercise in type I diabetes: comparison between the continuous-infusion insulin pump and intensified conventional therapy].
    Revista clinica espanola, 1986, Volume: 179, Issue:7

    Topics: Adult; Albuminuria; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Exercise Test; Fatty Acids; Fe

1986
Metabolic control of kidney hemodynamics in normal and insulin-dependent diabetic subjects. Effects of acetoacetic, lactic, and acetic acids.
    Diabetes, 1987, Volume: 36, Issue:9

    Topics: Acetates; Acetic Acid; Acetoacetates; Adolescent; Adult; Aged; Blood Glucose; Child; Diabetes Mellit

1987
Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine
    The Journal of clinical investigation, 1985, Volume: 75, Issue:6

    Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids

1985
Free insulin levels and metabolic effects of meal-time bolus and square-wave intraperitoneal insulin infusion in insulin-dependent diabetic patients.
    Diabetologia, 1985, Volume: 28, Issue:10

    Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonest

1985
Metabolic rhythms in adolescents with diabetes.
    Archives of disease in childhood, 1986, Volume: 61, Issue:2

    Topics: Activity Cycles; Adolescent; Blood Glucose; Child; Circadian Rhythm; Diabetes Mellitus, Type 1; Fema

1986
[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1985, Apr-15, Volume: 40, Issue:8

    Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Re

1985