lactic acid has been researched along with Autism in 12 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propionic acid (PPA) was injected intraperitoneally into 20 out of 30 rats for 5 days to establish an autism model." | 8.12 | Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy. ( Bozkurt, MF; Erbas, O; Ozkul, B; Sever, IH, 2022) |
| "A random retrospective chart review was conducted to document serum carnitine levels on 100 children with autism." | 7.72 | Relative carnitine deficiency in autism. ( Cummings, C; Filipek, PA; Gargus, JJ; Juranek, J; Nguyen, MT, 2004) |
| "Propionic acid (PPA) was injected intraperitoneally into 20 out of 30 rats for 5 days to establish an autism model." | 4.12 | Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy. ( Bozkurt, MF; Erbas, O; Ozkul, B; Sever, IH, 2022) |
| "A random retrospective chart review was conducted to document serum carnitine levels on 100 children with autism." | 3.72 | Relative carnitine deficiency in autism. ( Cummings, C; Filipek, PA; Gargus, JJ; Juranek, J; Nguyen, MT, 2004) |
| "Children with autism spectrum disorders (ASD) often suffer gastrointestinal problems consistent with imbalances in the gut microbial population." | 1.46 | In vitro fermentation of B-GOS: impact on faecal bacterial populations and metabolic activity in autistic and non-autistic children. ( Cela, D; Costabile, A; Gibson, GR; Grimaldi, R; Swann, JR; Tzortzis, G; Vulevic, J, 2017) |
| "The majority of children with autism (6 of 10) had complex I activity below control range values." | 1.36 | Mitochondrial dysfunction in autism. ( Giulivi, C; Hertz-Picciotto, I; Omanska-Klusek, A; Pessah, IN; Ross-Inta, C; Tassone, F; Wong, S; Zhang, YF, 2010) |
| "The increased prevalence of autism will have enormous future public implications and has stimulated intense research into potential etiologic factors." | 1.35 | Metabolic biomarkers related to energy metabolism in Saudi autistic children. ( Al-Ayadhi, L; Al-Mosalem, OA; Attas, O; El-Ansary, A, 2009) |
| "Epilepsy was present in 19 patients." | 1.33 | Mitochondrial dysfunction in autism spectrum disorders: a population-based study. ( Ataíde, A; Borges, L; Diogo, L; Garcia, P; Grazina, M; Marques, C; Miguel, T; Oliveira, CR; Oliveira, G; Vicente, AM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sever, IH | 1 |
| Ozkul, B | 1 |
| Bozkurt, MF | 1 |
| Erbas, O | 1 |
| Kato, Y | 1 |
| Yokokura, M | 1 |
| Iwabuchi, T | 1 |
| Murayama, C | 1 |
| Harada, T | 1 |
| Goto, T | 1 |
| Tamayama, T | 1 |
| Kameno, Y | 1 |
| Wakuda, T | 1 |
| Kuwabara, H | 1 |
| Benner, S | 1 |
| Senju, A | 1 |
| Tsukada, H | 1 |
| Nishizawa, S | 1 |
| Ouchi, Y | 1 |
| Yamasue, H | 1 |
| Mohammad Nezhady, MA | 1 |
| Cagnone, G | 1 |
| Joyal, JS | 1 |
| Chemtob, S | 1 |
| Grimaldi, R | 1 |
| Cela, D | 1 |
| Swann, JR | 1 |
| Vulevic, J | 1 |
| Gibson, GR | 1 |
| Tzortzis, G | 1 |
| Costabile, A | 1 |
| Al-Mosalem, OA | 1 |
| El-Ansary, A | 1 |
| Attas, O | 1 |
| Al-Ayadhi, L | 1 |
| Giulivi, C | 1 |
| Zhang, YF | 1 |
| Omanska-Klusek, A | 1 |
| Ross-Inta, C | 1 |
| Wong, S | 1 |
| Hertz-Picciotto, I | 1 |
| Tassone, F | 1 |
| Pessah, IN | 1 |
| Kosinovsky, B | 1 |
| Hermon, S | 1 |
| Yoran-Hegesh, R | 1 |
| Golomb, A | 1 |
| Senecky, Y | 1 |
| Goez, H | 1 |
| Kramer, U | 1 |
| Filipek, PA | 1 |
| Juranek, J | 1 |
| Nguyen, MT | 1 |
| Cummings, C | 1 |
| Gargus, JJ | 1 |
| Oliveira, G | 2 |
| Diogo, L | 2 |
| Grazina, M | 2 |
| Garcia, P | 1 |
| Ataíde, A | 2 |
| Marques, C | 2 |
| Miguel, T | 2 |
| Borges, L | 2 |
| Vicente, AM | 2 |
| Oliveira, CR | 1 |
| Correia, C | 1 |
| Coutinho, AM | 1 |
| Almeida, J | 1 |
| Oliveira, C | 1 |
| László, A | 1 |
| Horváth, E | 1 |
| Eck, E | 1 |
| Fekete, M | 1 |
| Martineau, J | 1 |
| Barthelemy, C | 1 |
| Lelord, G | 1 |
12 other studies available for lactic acid and Autism
| Article | Year |
|---|---|
Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy.
Topics: Animals; Antioxidants; Autistic Disorder; Behavior Rating Scale; Creatine; Finasteride; Lactic Acid; | 2022 |
Lower Availability of Mitochondrial Complex I in Anterior Cingulate Cortex in Autism: A Positron Emission Tomography Study.
Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Brain; Brain Diseases; Case-Control Studies; Ele | 2023 |
Lack of HCAR1, the lactate GPCR, signaling promotes autistic-like behavior.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Lactic Acid; Mice; Receptors, G-Protein-Couple | 2023 |
In vitro fermentation of B-GOS: impact on faecal bacterial populations and metabolic activity in autistic and non-autistic children.
Topics: Anti-Bacterial Agents; Autistic Disorder; Bacteroides; Bifidobacterium; Child; Clostridium; Fatty Ac | 2017 |
Metabolic biomarkers related to energy metabolism in Saudi autistic children.
Topics: Adenosine Triphosphatases; Adolescent; Apyrase; Asian People; Autistic Disorder; Biomarkers; Case-Co | 2009 |
Mitochondrial dysfunction in autism.
Topics: Autistic Disorder; Case-Control Studies; Child, Preschool; DNA Copy Number Variations; DNA, Mitochon | 2010 |
The yield of laboratory investigations in children with infantile autism.
Topics: Adolescent; Adult; Amino Acids; Autistic Disorder; Biomarkers; Blood Chemical Analysis; Child; Child | 2005 |
Relative carnitine deficiency in autism.
Topics: Adolescent; Alanine; Autistic Disorder; Carnitine; Child; Child, Preschool; Diagnostic and Statistic | 2004 |
Mitochondrial dysfunction in autism spectrum disorders: a population-based study.
Topics: Adolescent; Autistic Disorder; Child; Comorbidity; Cross-Sectional Studies; Epilepsy; Female; Humans | 2005 |
Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: no association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene.
Topics: Aspartic Acid; Autistic Disorder; Chromosome Mapping; DNA Mutational Analysis; DNA Primers; DNA, Mit | 2006 |
Serum serotonin, lactate and pyruvate levels in infantile autistic children.
Topics: Autistic Disorder; Child; Child, Preschool; Humans; Infant; Lactates; Lactic Acid; Pyruvates; Pyruvi | 1994 |
Long-term effects of combined vitamin B6-magnesium administration in an autistic child.
Topics: Autistic Disorder; Child, Preschool; Drug Therapy, Combination; Evoked Potentials, Auditory; Homovan | 1986 |