lactic acid has been researched along with Atherosclerosis in 19 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Atherosclerosis is a common and deadly cardiovascular disease with extremely high prevalence." | 1.51 | Activation of GPR81 by lactate inhibits oscillatory shear stress-induced endothelial inflammation by activating the expression of KLF2. ( Chen, T; Han, Y; Liu, Y; Song, S; Sun, Z, 2019) |
| "Oxidative capacity is decreased in type 2 diabetes." | 1.39 | Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study. ( Ballantyne, CM; Brancati, FL; Chu, AY; Guallar, E; Hoogeveen, RC; Juraschek, SP; Miller, ER; Pankow, JS; Schmidt, MI; Shantha, GP; Young, JH, 2013) |
| "The prevalence of type 2 diabetes rose across lactate quartiles (11, 14, 20 and 30%; P for trend <0." | 1.36 | Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study. ( Astor, BC; Ballantyne, CM; Brancati, FL; Crawford, SO; Hoogeveen, RC; Schmidt, MI; Young, JH, 2010) |
| "Accurate imaging of atherosclerosis is a growing necessity for timely treatment of the disease." | 1.35 | Preparation and initial characterization of biodegradable particles containing gadolinium-DTPA contrast agent for enhanced MRI. ( Ali, A; Brannon-Peppas, L; Chu, K; Doiron, AL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 15 (78.95) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Ouyang, J | 1 |
| Wang, H | 1 |
| Huang, J | 1 |
| Sun, Z | 1 |
| Han, Y | 2 |
| Song, S | 1 |
| Chen, T | 1 |
| Liu, Y | 1 |
| Rebholz, CM | 1 |
| Yu, B | 1 |
| Zheng, Z | 1 |
| Chang, P | 1 |
| Tin, A | 1 |
| Köttgen, A | 1 |
| Wagenknecht, LE | 1 |
| Coresh, J | 2 |
| Boerwinkle, E | 1 |
| Selvin, E | 2 |
| Misra, BB | 1 |
| Puppala, SR | 1 |
| Comuzzie, AG | 1 |
| Mahaney, MC | 1 |
| VandeBerg, JL | 1 |
| Olivier, M | 1 |
| Cox, LA | 1 |
| Juonala, M | 1 |
| Ellul, S | 1 |
| Lawlor, DA | 1 |
| Santos Ferreira, DL | 1 |
| Carlin, JB | 1 |
| Cheung, M | 1 |
| Dwyer, T | 1 |
| Wake, M | 1 |
| Saffery, R | 1 |
| Burgner, DP | 1 |
| Juraschek, SP | 2 |
| Miller, ER | 2 |
| Brancati, FL | 4 |
| Young, JH | 4 |
| Sinha, A | 1 |
| Shaporev, A | 1 |
| Nosoudi, N | 1 |
| Lei, Y | 1 |
| Vertegel, A | 1 |
| Lessner, S | 1 |
| Vyavahare, N | 1 |
| Nakashiro, S | 1 |
| Matoba, T | 1 |
| Umezu, R | 1 |
| Koga, J | 1 |
| Tokutome, M | 1 |
| Katsuki, S | 1 |
| Nakano, K | 1 |
| Sunagawa, K | 1 |
| Egashira, K | 1 |
| Nakamura, F | 1 |
| Ishida, Y | 1 |
| Sawada, D | 1 |
| Ashida, N | 1 |
| Sugawara, T | 1 |
| Sakai, M | 1 |
| Goto, T | 1 |
| Kawada, T | 1 |
| Fujiwara, S | 1 |
| Zhao, Y | 1 |
| Jiang, C | 1 |
| He, J | 1 |
| Guo, Q | 1 |
| Lu, J | 1 |
| Yang, Y | 1 |
| Zhang, W | 1 |
| Liu, J | 1 |
| Doiron, AL | 1 |
| Chu, K | 1 |
| Ali, A | 1 |
| Brannon-Peppas, L | 1 |
| Crawford, SO | 2 |
| Hoogeveen, RC | 3 |
| Astor, BC | 2 |
| Ballantyne, CM | 3 |
| Schmidt, MI | 3 |
| Leppänen, O | 2 |
| Ekstrand, M | 1 |
| Bräsen, JH | 1 |
| Levin, M | 2 |
| Mongraw-Chaffin, ML | 1 |
| Matsushita, K | 1 |
| Kimmel, DW | 1 |
| Dole, WP | 1 |
| Cliffel, DE | 1 |
| Shantha, GP | 1 |
| Chu, AY | 1 |
| Guallar, E | 1 |
| Pankow, JS | 1 |
| Zhu, S | 1 |
| Goldschmidt-Clermont, PJ | 1 |
| Dong, C | 1 |
| Björnheden, T | 1 |
| Evaldsson, M | 1 |
| Borén, J | 1 |
| Wiklund, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alkaline Diet for Insulin Sensitivity[NCT02501343] | 32 participants (Actual) | Interventional | 2015-03-31 | Completed | |||
| The Relation Between Acute Changes in the Systemic Inflammatory Response, Thiamine and Magnesium Concentrations and Transketolase Activity After Elective Knee Arthroplasty.[NCT03554668] | 47 participants (Actual) | Observational | 2018-01-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Atherosclerosis
| Article | Year |
|---|---|
The role of lactate in cardiovascular diseases.
Topics: Atherosclerosis; Atrial Fibrillation; Cardiovascular Diseases; Humans; Lactic Acid; Myocardial Infar | 2023 |
18 other studies available for lactic acid and Atherosclerosis
| Article | Year |
|---|---|
Activation of GPR81 by lactate inhibits oscillatory shear stress-induced endothelial inflammation by activating the expression of KLF2.
Topics: Atherosclerosis; Chemokine CCL2; Endothelial Cells; HMGB1 Protein; Human Umbilical Vein Endothelial | 2019 |
Serum metabolomic profile of incident diabetes.
Topics: Amino Acids, Branched-Chain; Asparagine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; | 2018 |
Analysis of serum changes in response to a high fat high cholesterol diet challenge reveals metabolic biomarkers of atherosclerosis.
Topics: Animals; Aorta; Aorta, Thoracic; Asparagine; Atherosclerosis; Biomarkers; Cholesterol; Cholesterol, | 2019 |
A Cross-Cohort Study Examining the Associations of Metabolomic Profile and Subclinical Atherosclerosis in Children and Their Parents: The Child Health CheckPoint Study and Avon Longitudinal Study of Parents and Children.
Topics: Adult; Amino Acids; Apolipoprotein A-I; Apolipoproteins B; Asymptomatic Diseases; Atherosclerosis; A | 2019 |
Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study.
Topics: Adult; Aged; Atherosclerosis; Biomarkers; Blood Glucose; Community-Based Participatory Research; Dia | 2013 |
Nanoparticle targeting to diseased vasculature for imaging and therapy.
Topics: Animals; Aortic Aneurysm; Atherosclerosis; Diagnostic Imaging; Drug Delivery Systems; Lactic Acid; M | 2014 |
Pioglitazone-Incorporated Nanoparticles Prevent Plaque Destabilization and Rupture by Regulating Monocyte/Macrophage Differentiation in ApoE-/- Mice.
Topics: Administration, Intravenous; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Brachiocep | 2016 |
Fragmented Lactic Acid Bacterial Cells Activate Peroxisome Proliferator-Activated Receptors and Ameliorate Dyslipidemia in Obese Mice.
Topics: Animals; Atherosclerosis; Dyslipidemias; Insulin Resistance; Lactic Acid; Lipoproteins, HDL; Lipopro | 2016 |
Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages and Promote Beneficial Antiatherosclerotic Mechanisms.
Topics: Animals; Atherosclerosis; Atorvastatin; Biological Transport; Cholesterol; Dextran Sulfate; Drug Car | 2017 |
Preparation and initial characterization of biodegradable particles containing gadolinium-DTPA contrast agent for enhanced MRI.
Topics: Atherosclerosis; Cell Line; Contrast Media; Endothelial Cells; Gadolinium DTPA; Humans; Lactic Acid; | 2008 |
Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Carotid Arteries; Cross-Sectional Studies | 2010 |
Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Carotid Arteries; Cross-Sectional Studies | 2010 |
Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Carotid Arteries; Cross-Sectional Studies | 2010 |
Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Carotid Arteries; Cross-Sectional Studies | 2010 |
Nanoburrs seek, heal injury in artery.
Topics: Absorbable Implants; Atherosclerosis; Cardiotonic Agents; Coronary Restenosis; Coronary Vessels; Dru | 2011 |
Bioluminescence imaging of energy depletion in vascular pathology: patent ductus arteriosus and atherosclerosis.
Topics: Adenosine Triphosphate; Animals; Arteries; Atherosclerosis; Ductus Arteriosus, Patent; Energy Metabo | 2012 |
Diabetes medication use and blood lactate level among participants with type 2 diabetes: the atherosclerosis risk in communities carotid MRI study.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Blood Glucose; Cohort Studies; Cross-Sectional Studies; Di | 2012 |
Application of multianalyte microphysiometry to characterize macrophage metabolic responses to oxidized LDL and effects of an apoA-1 mimetic.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Biomimetic Materials; Cell Line; Glucose; Lactic Acid; | 2013 |
Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study.
Topics: Atherosclerosis; Case-Control Studies; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; In | 2013 |
Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.
Topics: Aorta; Atherosclerosis; Azacitidine; Biological Transport; Cell Proliferation; Cells, Cultured; CpG | 2005 |
ATP depletion in macrophages in the core of advanced rabbit atherosclerotic plaques in vivo.
Topics: Adenosine Triphosphate; Animals; Aorta; Atherosclerosis; Cell Hypoxia; Glucose; Glycogen; Immunohist | 2006 |