lactic acid has been researched along with Ataxia with Lactic Acidosis 2 in 14 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A new patient with neonatal lactic acidosis due to pyruvate carboxylase deficiency is described." | 8.77 | [Neonatal lactic acidosis caused by severe pyruvate carboxylase deficiency]. ( Cortés Coto, MT; del Valle Martínez, J; García Aparicio, J; García Muñoz, MJ; Merinero Cortés, B; Pérez-Cerdá Silvestre, C; Sáez Pérez, E; Ugarte Pérez, M, 1988) |
| "Two patients with biotin-responsive multiple carboxylase deficiency, both presenting with predominant lactic acidosis, are reported." | 7.66 | Lactic acidosis in biotin-responsive multiple carboxylase deficiency caused by holocarboxylase synthetase deficiency of early and late onset. ( Brewster, T; Gravel, RA; Robinson, BH; Saunders, M; Sherwood, WG, 1982) |
| "A new patient with neonatal lactic acidosis due to pyruvate carboxylase deficiency is described." | 4.77 | [Neonatal lactic acidosis caused by severe pyruvate carboxylase deficiency]. ( Cortés Coto, MT; del Valle Martínez, J; García Aparicio, J; García Muñoz, MJ; Merinero Cortés, B; Pérez-Cerdá Silvestre, C; Sáez Pérez, E; Ugarte Pérez, M, 1988) |
| "To report the clinical history and laboratory evaluation of a patient presenting with lactic acidosis secondary to pyruvate carboxylase deficiency." | 3.69 | Prolonged survival in pyruvate carboxylase deficiency: lack of correlation with enzyme activity in cultured fibroblasts. ( Depalma, L; Nayar, R; Rifai, N; Stern, HJ, 1995) |
| "Two patients with biotin-responsive multiple carboxylase deficiency, both presenting with predominant lactic acidosis, are reported." | 3.66 | Lactic acidosis in biotin-responsive multiple carboxylase deficiency caused by holocarboxylase synthetase deficiency of early and late onset. ( Brewster, T; Gravel, RA; Robinson, BH; Saunders, M; Sherwood, WG, 1982) |
| "At age 3(1/2) years she has profound mental retardation, spasticity, and grand mal and myoclonic seizures only partially controlled by anticonvulsants." | 1.30 | Treatment of pyruvate carboxylase deficiency with high doses of citrate and aspartate. ( Ahmad, A; Artigas-Lopez, M; Kahler, SG; Kishnani, PS; Millington, DS; Pappu, AS; Steiner, R; Van Hove, JL, 1999) |
| "Isolated pyruvate carboxylase deficiency was found to present in two different forms, one with lactic acidaemia and mental retardation, the other with lactic acidaemia, hyperammonaemia citrullinaemia and hyperlysinaemia." | 1.27 | Lactic acidaemia. ( Robinson, BH; Sherwood, WG, 1984) |
| "Isolated pyruvate carboxylase deficiency is reviewed in detail with a report of a recent case and a discussion of the biochemical consequences." | 1.27 | Pyruvate carboxylase deficiency. ( Alberti, KG; Bartlett, K; Dale, G; Ghneim, HK; Stirk, JH, 1984) |
| "Treatment with aspartic acid and thiamine over a period of seven years resulted in biochemical improvement and a stable neurological condition." | 1.26 | A patient with pyruvate carboxylase deficiency in the liver: treatment with aspartic acid and thiamine. ( Baal, MG; Gabreëls, FJ; Gijsbers, TH; Hommes, FA; Kok, JC; Lamers, KJ; Renier, WO, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Robinson, BH | 3 |
| Sherwood, WG | 2 |
| Bartlett, K | 1 |
| Ghneim, HK | 1 |
| Stirk, JH | 1 |
| Dale, G | 1 |
| Alberti, KG | 1 |
| Chalmers, RA | 1 |
| Sweetman, L | 1 |
| Haworth, JC | 1 |
| Perry, TL | 1 |
| Baal, MG | 1 |
| Gabreëls, FJ | 1 |
| Renier, WO | 1 |
| Hommes, FA | 1 |
| Gijsbers, TH | 1 |
| Lamers, KJ | 1 |
| Kok, JC | 1 |
| Saunders, M | 1 |
| Brewster, T | 1 |
| Gravel, RA | 1 |
| Stern, HJ | 2 |
| Nayar, R | 1 |
| Depalma, L | 1 |
| Rifai, N | 1 |
| Higgins, JJ | 1 |
| Ide, SE | 1 |
| Oghalai, JS | 1 |
| Polymeropoulos, MH | 1 |
| Ahmad, A | 1 |
| Kahler, SG | 1 |
| Kishnani, PS | 1 |
| Artigas-Lopez, M | 1 |
| Pappu, AS | 1 |
| Steiner, R | 1 |
| Millington, DS | 1 |
| Van Hove, JL | 1 |
| Merinero Cortés, B | 1 |
| del Valle Martínez, J | 1 |
| Pérez-Cerdá Silvestre, C | 1 |
| García Muñoz, MJ | 1 |
| Cortés Coto, MT | 1 |
| García Aparicio, J | 1 |
| Sáez Pérez, E | 1 |
| Ugarte Pérez, M | 1 |
| Krause, KH | 1 |
| Bonjour, JP | 1 |
| Berlit, P | 1 |
| Kochen, W | 1 |
| Erasmus, C | 1 |
| Mienie, LJ | 1 |
| Reinecke, CJ | 1 |
| Wadman, SK | 1 |
2 reviews available for lactic acid and Ataxia with Lactic Acidosis 2
| Article | Year |
|---|---|
Lactic acidosis in paediatrics: clinical and laboratory evaluation.
Topics: Acidosis, Lactic; Adult; Child; Citric Acid Cycle; Female; Gluconeogenesis; Glycogen; Humans; Infant | 1994 |
[Neonatal lactic acidosis caused by severe pyruvate carboxylase deficiency].
Topics: Acidosis, Lactic; Humans; Infant; Infant, Newborn; Lactates; Lactic Acid; Male; Metabolism, Inborn E | 1988 |
12 other studies available for lactic acid and Ataxia with Lactic Acidosis 2
| Article | Year |
|---|---|
Lactic acidaemia.
Topics: Abnormalities, Multiple; Child; Humans; Lactates; Lactic Acid; Metabolism, Inborn Errors; Pyruvate C | 1984 |
Pyruvate carboxylase deficiency.
Topics: Carboxy-Lyases; Citrulline; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Metabolism, Inborn | 1984 |
Organic acids in urine of patients with congenital lactic acidoses: an aid to differential diagnosis.
Topics: Acidosis; Acids; Citric Acid Cycle; Cytochromes; Diagnosis, Differential; Gluconeogenesis; Humans; L | 1984 |
Two forms of biotin-responsive multiple carboxylase deficiency.
Topics: Acute Disease; Biotin; Carbon-Carbon Ligases; Chronic Disease; Fibroblasts; Humans; Hydroxy Acids; I | 1981 |
Lactic acidosis due to pyruvate carboxylase deficiency.
Topics: Acidosis; Humans; Infant; Lactates; Lactic Acid; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP | 1981 |
A patient with pyruvate carboxylase deficiency in the liver: treatment with aspartic acid and thiamine.
Topics: Aspartic Acid; Child; Female; Humans; Lactates; Lactic Acid; Liver; Psychological Tests; Pyruvate Ca | 1981 |
Lactic acidosis in biotin-responsive multiple carboxylase deficiency caused by holocarboxylase synthetase deficiency of early and late onset.
Topics: Acidosis; Age Factors; Biotin; Carbon-Carbon Ligases; Carbon-Nitrogen Ligases; Carboxy-Lyases; Cells | 1982 |
Prolonged survival in pyruvate carboxylase deficiency: lack of correlation with enzyme activity in cultured fibroblasts.
Topics: Acidosis, Lactic; Adult; Alanine; Cells, Cultured; Child; Child, Preschool; Female; Fibroblasts; Hum | 1995 |
Lack of mutations in the biotin-binding region of the pyruvate carboxylase (PC) gene in a family with partial PC deficiency.
Topics: Binding Sites; Biotin; Child; Female; Humans; Lactic Acid; Male; Molecular Sequence Data; Mutation; | 1997 |
Treatment of pyruvate carboxylase deficiency with high doses of citrate and aspartate.
Topics: Amino Acids; Aspartic Acid; Child, Preschool; Citric Acid; Dose-Response Relationship, Drug; Female; | 1999 |
Biotin status of epileptics.
Topics: Adult; Anticonvulsants; Biotin; Carbon-Carbon Ligases; Carboxy-Lyases; Epilepsy; Female; Humans; Lac | 1985 |
Organic aciduria in late-onset biotin-responsive multiple carboxylase deficiency.
Topics: Biotin; Carbon-Carbon Ligases; Carboxy-Lyases; Female; Humans; Infant; Lactates; Lactic Acid; Ligase | 1985 |