lactic acid has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 16 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have used diabetic autonomic neuropathy as a model of chronic pulmonary denervation to study the ventilatory response to incremental exercise in 20 diabetic subjects, 10 with (Dan+) and 10 without (Dan-) autonomic dysfunction, and in 10 normal control subjects." | 2.68 | Ventilatory response to exercise in diabetic subjects with autonomic neuropathy. ( Bottini, P; Casucci, G; Dottorini, ML; Puxeddu, E; Scionti, L; Sorbini, CA; Tantucci, C, 1996) |
| "We conclude that DAN, long IDDM duration per se, and antecedent recent hypoglycemia contribute to different extents to impaired adrenaline responses and hypoglycemia unawareness." | 1.30 | Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation. ( Bolli, GB; Bottini, P; Brunetti, P; Ciofetta, M; Del Sindaco, P; Di Vincenzo, A; Fanelli, C; Lalli, C; Lepore, M; Pampanelli, S; Porcellati, F, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Jha, MK | 2 |
| Ament, XH | 1 |
| Yang, F | 1 |
| Liu, Y | 1 |
| Polydefkis, MJ | 1 |
| Pellerin, L | 1 |
| Morrison, BM | 1 |
| Bhusal, A | 1 |
| Rahman, MH | 2 |
| Lee, WH | 1 |
| Lee, IK | 2 |
| Suk, K | 2 |
| Kim, JH | 2 |
| Nam, Y | 1 |
| Lee, MG | 1 |
| Go, Y | 1 |
| Harris, RA | 1 |
| Park, DH | 1 |
| Kook, H | 1 |
| Hazekawa, M | 1 |
| Sakai, Y | 1 |
| Yoshida, M | 1 |
| Haraguchi, T | 1 |
| Morisaki, T | 1 |
| Uchida, T | 1 |
| Won, SJ | 1 |
| Jang, BG | 1 |
| Yoo, BH | 1 |
| Sohn, M | 1 |
| Lee, MW | 1 |
| Choi, BY | 1 |
| Song, HK | 1 |
| Suh, SW | 1 |
| Jensen, RV | 1 |
| Støttrup, NB | 1 |
| Kristiansen, SB | 1 |
| Bøtker, HE | 1 |
| Tilton, RG | 1 |
| Chang, K | 1 |
| Nyengaard, JR | 1 |
| Van den Enden, M | 1 |
| Ido, Y | 1 |
| Williamson, JR | 1 |
| McLellan, AC | 1 |
| Thornalley, PJ | 1 |
| Benn, J | 1 |
| Sonksen, PH | 1 |
| Tantucci, C | 1 |
| Bottini, P | 2 |
| Dottorini, ML | 1 |
| Puxeddu, E | 1 |
| Casucci, G | 1 |
| Scionti, L | 1 |
| Sorbini, CA | 1 |
| Fanelli, C | 1 |
| Pampanelli, S | 1 |
| Lalli, C | 1 |
| Del Sindaco, P | 1 |
| Ciofetta, M | 1 |
| Lepore, M | 1 |
| Porcellati, F | 1 |
| Di Vincenzo, A | 1 |
| Brunetti, P | 1 |
| Bolli, GB | 1 |
| Suzuki, S | 1 |
| Hinokio, Y | 1 |
| Ohtomo, M | 1 |
| Hirai, M | 1 |
| Hirai, A | 1 |
| Chiba, M | 1 |
| Kasuga, S | 1 |
| Satoh, Y | 1 |
| Akai, H | 1 |
| Toyota, T | 1 |
| Hilsted, J | 1 |
| Richter, EA | 1 |
| Madsbad, S | 1 |
| Tronier, B | 1 |
| Christensen, NJ | 1 |
| Hildebrandt, P | 1 |
| Galbo, H | 1 |
| Damkjaer, M | 1 |
| Yao, H | 1 |
| Sadoshima, S | 1 |
| Nishimura, Y | 1 |
| Fujii, K | 1 |
| Oshima, M | 1 |
| Ishitsuka, T | 1 |
| Fujishima, M | 1 |
| Low, PA | 3 |
| Schmelzer, JD | 3 |
| Ward, KK | 2 |
| Yao, JK | 1 |
| Curran, GL | 1 |
| Poduslo, JF | 1 |
| Ward, K | 1 |
| Brimijoin, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Controlled Trial of the Effect of Remote Ischaemic Conditioning on Coronary Endothelial Function in Patients With Angina.[NCT02666235] | Phase 2 | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for lactic acid and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Ventilatory response to exercise in diabetic subjects with autonomic neuropathy.
Topics: Adult; Anaerobic Threshold; Autonomic Nervous System Diseases; Blood Glucose; Carbon Dioxide; Diabet | 1996 |
The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation.
Topics: Adult; C-Peptide; Coenzymes; Deafness; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropat | 1998 |
14 other studies available for lactic acid and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Reducing monocarboxylate transporter MCT1 worsens experimental diabetic peripheral neuropathy.
Topics: Animals; Axons; Behavior, Animal; Demyelinating Diseases; Diabetes Mellitus, Experimental; Diabetic | 2020 |
Satellite glia as a critical component of diabetic neuropathy: Role of lipocalin-2 and pyruvate dehydrogenase kinase-2 axis in the dorsal root ganglion.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ganglia, Spinal; Inflammation; Lact | 2021 |
Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ganglia, Spinal; G | 2016 |
Preparation of ONO-1301-loaded poly(lactide-co-glycolide) microspheres and their effect on nerve conduction velocity.
Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetic Neuropathie | 2011 |
Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Cell Death; Diabetic Neuropathies; Electrocardiograp | 2012 |
Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients.
Topics: Aged; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Hemodynamics; Humans; Ische | 2012 |
Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Neuropathies; Eye; Fructos | 1995 |
Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications.
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathi | 1994 |
Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1; | 1997 |
Increased metabolic sensitivity towards adrenaline in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Blood Glucose; Diabetic Neuropathies; Epinephrine; Fatty Acids, N | 1985 |
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypo | 1989 |
Experimental chronic hypoxic neuropathy: relevance to diabetic neuropathy.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Electrophysiology; Glycated Hemoglobin; Hexo | 1986 |
Effect of hyperbaric oxygenation on normal and chronic streptozotocin diabetic peripheral nerves.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Biological Transport, Active; Diabetes Mellitus, | 1988 |
Ischemic conduction failure and energy metabolism in experimental diabetic neuropathy.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Diabetic Neurop | 1985 |