Page last updated: 2024-10-17

lactic acid and Asthma

lactic acid has been researched along with Asthma in 46 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Plasma albuterol was significantly correlated with serum lactate concentration after adjusting for asthma severity."9.19Albuterol administration is commonly associated with increases in serum lactate in patients with asthma treated for acute exacerbation of asthma. ( Aubuchon, K; Ferguson, I; House, SL; Johnson, K; Lewis, LM; Matsuda, K; Schneider, J, 2014)
" In this study, we have evaluated anti-asthmatic efficacy of inhalable montelukast-loaded large porous particulate formulations in ovalbumin-induced rat airway inflammation model that mimics asthma."7.80Aerosolized montelukast polymeric particles-an alternative to oral montelukast-alleviate symptoms of asthma in a rodent model. ( Ahsan, F; Gupta, N; Patel, B, 2014)
" Laboratory findings showed hypokalemia, hypophosphatemia, and lactic acidosis."7.78Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. ( Hantson, P; Manara, A; Thys, F; Vanpee, D, 2012)
" His case was reviewed, and the lactic acidosis was thought to be caused by inhaled β2-agonist use."7.77Take my breath away: a case of lactic acidosis in an asthma exacerbation. ( McGonigle, R; Woods, RA, 2011)
"Estimate influences of standard physical exercise on lactic acid concentration and acid-base equilibrium in patients with mild and moderate bronchial asthma compared with healthy trained persons and do not ones."7.72[Influence of physical effort on concentration of lactic acid and acid-base equilibrium in patients with mild and moderate bronchial asthma]. ( Dziedziczko, A; Kuźmiński, A, 2004)
"Plasma albuterol was significantly correlated with serum lactate concentration after adjusting for asthma severity."5.19Albuterol administration is commonly associated with increases in serum lactate in patients with asthma treated for acute exacerbation of asthma. ( Aubuchon, K; Ferguson, I; House, SL; Johnson, K; Lewis, LM; Matsuda, K; Schneider, J, 2014)
"Montelukast, a cysteinyl leukotriene receptor antagonist available as oral tablets, is used as a second-line therapy in asthma."3.85Aerosolizable modified-release particles of montelukast improve retention and availability of the drug in the lungs. ( Ahsan, F; Patel, B; Rashid, J, 2017)
" In this study, we have evaluated anti-asthmatic efficacy of inhalable montelukast-loaded large porous particulate formulations in ovalbumin-induced rat airway inflammation model that mimics asthma."3.80Aerosolized montelukast polymeric particles-an alternative to oral montelukast-alleviate symptoms of asthma in a rodent model. ( Ahsan, F; Gupta, N; Patel, B, 2014)
" Laboratory findings showed hypokalemia, hypophosphatemia, and lactic acidosis."3.78Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. ( Hantson, P; Manara, A; Thys, F; Vanpee, D, 2012)
" His case was reviewed, and the lactic acidosis was thought to be caused by inhaled β2-agonist use."3.77Take my breath away: a case of lactic acidosis in an asthma exacerbation. ( McGonigle, R; Woods, RA, 2011)
"Estimate influences of standard physical exercise on lactic acid concentration and acid-base equilibrium in patients with mild and moderate bronchial asthma compared with healthy trained persons and do not ones."3.72[Influence of physical effort on concentration of lactic acid and acid-base equilibrium in patients with mild and moderate bronchial asthma]. ( Dziedziczko, A; Kuźmiński, A, 2004)
"Terbutaline is a prohibited drug except for athletes with a therapeutic use exemption certificate; terbutaline's effects on endurance performance are relatively unknown."2.90The Effects of Inhaled Terbutaline on 3-km Running Time-Trial Performance. ( Chester, NJ; Dickinson, JW; Loosemore, M; Molphy, J; Whyte, G, 2019)
" QTc, blood pressure and heart rate over 12h, and plasma lactate and glucose over 3h following dosing were assessed."2.73Tolerability of high cumulative doses of the HFA modulite beclomethasone dipropionate/formoterol combination inhaler in asthmatic patients. ( Acerbi, D; Borrill, Z; Meuleners, L; Piccinno, A; Poli, G; Singh, D; Woodcock, A, 2008)
"While respiratory alkalosis occurred in patients with better preservation of FEV1, respiratory acidosis was observed with more severe airway obstruction, as was increased lactate in the majority of patients, independent of PaO(2) and PaCO(2) levels."1.39Acid-base patterns in acute severe asthma. ( Adrogué, HJ; Gonzalez, S; Menga, G; Raimondi, GA; Zaltsman, J, 2013)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19907 (15.22)18.7374
1990's5 (10.87)18.2507
2000's7 (15.22)29.6817
2010's24 (52.17)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Guo, X1
Zuo, X1
Zhou, Z1
Gu, Y1
Zheng, H1
Wang, X2
Wang, G1
Xu, C1
Wang, F1
Niu, Y1
Nie, Q1
Dong, L1
Zhang, J1
Liu, SF1
Song, W1
Wu, G1
Song, D1
Guyther, J1
Cantwell, L1
Morris, AS1
Sebag, SC1
Paschke, JD1
Wongrakpanich, A1
Ebeid, K1
Anderson, ME1
Grumbach, IM1
Salem, AK1
Daniels, CE1
Litin, SC1
Bundrick, JB1
Qian, X1
Aboushousha, R1
van de Wetering, C1
Chia, SB1
Amiel, E1
Schneider, RW1
van der Velden, JLJ1
Lahue, KG1
Hoagland, DA1
Casey, DT1
Daphtary, N1
Ather, JL1
Randall, MJ1
Aliyeva, M1
Black, KE1
Chapman, DG1
Lundblad, LKA1
McMillan, DH1
Dixon, AE1
Anathy, V1
Irvin, CG1
Poynter, ME1
Wouters, EFM1
Vacek, PM1
Henket, M1
Schleich, F1
Louis, R1
van der Vliet, A1
Janssen-Heininger, YMW1
Molphy, J1
Dickinson, JW1
Chester, NJ1
Loosemore, M1
Whyte, G1
Papamichael, MM1
Katsardis, C1
Erbas, B1
Itsiopoulos, C1
Tsoukalas, D1
Raimondi, GA1
Gonzalez, S1
Zaltsman, J1
Menga, G1
Adrogué, HJ1
Lewis, LM2
Ferguson, I2
House, SL2
Aubuchon, K2
Schneider, J2
Johnson, K2
Matsuda, K2
de Oliveira, JF1
Garreto, DV1
da Silva, MC1
Fortes, TS1
de Oliveira, RB1
Nascimento, FR1
Da Costa, FB1
Grisotto, MA1
Nicolete, R1
Patel, B3
Gupta, N2
Ahsan, F3
Rodrigo, GJ1
Senthilkumaran, S1
Shah, S1
Menezes, RG1
Thirumalaikolundusubramanian, P1
Claret, PG1
Bobbia, X1
de La Coussaye, JE1
Greguš, M1
Foret, F1
Kindlová, D1
Pokojová, E1
Plutinský, M1
Doubková, M1
Merta, Z1
Binková, I1
Skřičková, J1
Kubáň, P1
Tomasiak-Lozowska, MM1
Rusak, T1
Misztal, T1
Bodzenta-Lukaszyk, A1
Tomasiak, M1
McAvoy, JC1
Khurana, A1
Rashid, J1
Matsuo, Y1
Ishihara, T1
Ishizaki, J1
Miyamoto, K1
Higaki, M1
Yamashita, N1
Kovacevic, A1
Schwahn, B1
Schuster, A1
Oh, YJ1
Lee, J1
Seo, JY1
Rhim, T1
Kim, SH1
Yoon, HJ1
Lee, KY1
Matsunaga, Y1
Inoue, H1
Fukuyama, S1
Yoshida, H1
Moriwaki, A1
Matsumoto, T1
Matsumoto, K1
Asai, Y1
Kubo, M1
Yoshimura, A1
Nakanishi, Y1
McGonigle, R1
Woods, RA1
Ostroukhova, M1
Goplen, N1
Karim, MZ1
Michalec, L1
Guo, L1
Liang, Q1
Alam, R2
Manara, A1
Hantson, P1
Vanpee, D1
Thys, F1
Dziedziczko, A1
Kuźmiński, A1
Pytte, M1
Opdahl, H1
Skaga, NO1
Jee, R1
Brownlow, H1
Hulme, J1
Bohn, D1
Singh, D1
Piccinno, A1
Borrill, Z1
Poli, G1
Acerbi, D1
Meuleners, L1
Woodcock, A1
Hrabac, B1
Shephard, RJ1
Inbar, O1
Alvarez, DX1
Lyons, HA1
Henriksen, JM1
Nielsen, TT1
Dahl, R1
Robertson, W1
Simkins, J1
O'Hickey, SP1
Freeman, S1
Cayton, RM1
Counil, FP1
Varray, A1
Karila, C1
Hayot, M1
Voisin, M1
Préfaut, C1
Rabbat, A1
Laaban, JP1
Boussairi, A1
Rochemaure, J1
Forsythe, PA1
Rankin, JA1
Boyars, MC1
Lett-Brown, MA1
Grant, JA1
Cochrane, LM1
Clark, CJ1
Freeman, W1
Nute, MG1
Williams, C1
Okrent, DG1
Tessler, S1
Twersky, RA1
Tashkin, DP1
Hollmann, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II, Randomized, Modified Single-Blind, Placebo-Controlled Dose Escalation Study to Evaluate the Safety and Efficacy of MN-221 When Administered Intravenously as an Adjunct to Standard Therapy to Adults With an Acute Exacerbation of Asthma[NCT00683449]Phase 229 participants (Actual)Interventional2008-06-30Terminated (stopped due to Data from Dose Groups 1,2 and other MN-221 studies resulted in the determination of a more appropriate dosing scheme for MN-221 in subjects with asthma.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change of FEV1 (Forced Expiratory Volume in 1 Second) Expressed as Percent of Predicted After Two Doses of Albuterol (5 mg Each) and Ipratropium (0.5 mg Each) When Compared to FEV1 at Hour 2 After the Start of the Infusion of MN-221 or Placebo.

The primary efficacy summary was change from Baseline in FEV1 (percent predicted), at Hour 2. Baseline was defined as FEV1 (percent predicted) after two doses of albuterol (5 mg each) and ipratropium (0.5 mg each) and FEV1 (percent predicted) FEV1 at Hour 2 was defined as the FEV1 (percent predicted) at 2 hours after the start of the infusion of MN-221 or placebo. Change from Baseline in FEV1 (percent predicted), was summarized by treatment group at Hour 2. (NCT00683449)
Timeframe: Baseline and Hour 2

InterventionFEV1 (percent of predicted) (Mean)
240 μg MN-221 i.v. (Intravenous) Infusion for 15 Minutes16.57
MN-221 Placebo i.v. Infusion3.88
1,000-1,080 μg MN-221 i.v.3.03
450 μg MN-221 i.v. for 15 Minutes4.27
1,995 μg MN-221 i.v. Over 15 Minutes and 25 Minutes-0.82

FEV1 (L) The Forced Expiratory Volume in One Second as Measured in Liters Per Second.

FEV1 (L) was determined over time using a spirometer. Measure the mean change in FEV1 (L) from Baseline. (NCT00683449)
Timeframe: Baseline to Hour 2

Interventionliters per second (Mean)
MN-221 at 16.0 μg/Min for 15 Min (Total 240 μg)0.60
Placebo Administered Intravenously0.10
450 μg MN-221 Given i.v.0.12
1,000-1,080 μg MN-221 Given i.v. for 15 Minutes0.10
1,995 MN-221 Administered i.v. for 15 Minutes and 25 Minutes-0.02

Hospital Admission Rate During Visit 1

After a patient in the emergency department (ED) presents with an acute exacerbation of asthma, the hospital proceeds with SOC procedures for this condition. Despite treatment in the ED, it is sometimes necessary to admit the patient into the hospital. In the study described here, the rate of hospital admissions was recorded. (NCT00683449)
Timeframe: Hour -1.5 through Hour 5

Interventionparticipants (Number)
240 μg MN-221 i.v. (Intravenous) Infusion for 15 Minutes0
MN-221 Placebo i.v. Infusion7
1,000-1,080 μg MN-221 i.v.0
450 μg MN-221 i.v. for 15 Minutes3
1,995 μg MN-221 i.v. Over 15 Minutes and 25 Minutes1

Reviews

3 reviews available for lactic acid and Asthma

ArticleYear
PLGA-Based Micro/Nanoparticles: An Overview of Their Applications in Respiratory Diseases.
    International journal of molecular sciences, 2023, Feb-22, Volume: 24, Issue:5

    Topics: Asthma; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polygl

2023
Big Tests in Little People.
    Emergency medicine clinics of North America, 2021, Volume: 39, Issue:3

    Topics: Asthma; Biomarkers; Child; Fibrin Fibrinogen Degradation Products; Heart Diseases; Humans; Infection

2021
Exercise-induced bronchospasm - pathophysiology and treatment.
    Canadian journal of applied sport sciences. Journal canadien des sciences appliquees au sport, 1981, Volume: 6, Issue:3

    Topics: Adult; Age Factors; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Carbon Dioxide; Child;

1981

Trials

6 trials available for lactic acid and Asthma

ArticleYear
The Effects of Inhaled Terbutaline on 3-km Running Time-Trial Performance.
    International journal of sports physiology and performance, 2019, 07-01, Volume: 14, Issue:6

    Topics: Administration, Inhalation; Adult; Asthma; Athletic Performance; Female; Forced Expiratory Volume; H

2019
Albuterol administration is commonly associated with increases in serum lactate in patients with asthma treated for acute exacerbation of asthma.
    Chest, 2014, Volume: 145, Issue:1

    Topics: Adult; Albuterol; Asthma; Bronchodilator Agents; Disease Progression; Double-Blind Method; Drug Ther

2014
Tolerability of high cumulative doses of the HFA modulite beclomethasone dipropionate/formoterol combination inhaler in asthmatic patients.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Anti-Inflammator

2008
Does single dose salmeterol affect exercise capacity in asthmatic men?
    The European respiratory journal, 1994, Volume: 7, Issue:11

    Topics: Adult; Albuterol; Asthma; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Exercise T

1994
Wingate test performance in children with asthma: aerobic or anaerobic limitation?
    Medicine and science in sports and exercise, 1997, Volume: 29, Issue:4

    Topics: Adolescent; Anaerobic Threshold; Asthma; Child; Epinephrine; Exercise Test; Humans; Lactic Acid; Mal

1997
Benefits and problems of a physical training programme for asthmatic patients.
    Thorax, 1990, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Asthma; Carbon Dioxide; Exercise Therapy; Female; Forced Expiratory Volume; Heart

1990

Other Studies

37 other studies available for lactic acid and Asthma

ArticleYear
Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
    Scientific reports, 2020, 02-06, Volume: 10, Issue:1

    Topics: Animals; Asthma; Bronchoconstrictor Agents; Cells, Cultured; Disease Models, Animal; Female; Glycoly

2020
Cationic CaMKII Inhibiting Nanoparticles Prevent Allergic Asthma.
    Molecular pharmaceutics, 2017, 06-05, Volume: 14, Issue:6

    Topics: Animals; Asthma; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Drug Delivery Systems; Lactic A

2017
Clinical pearls in pulmonary diseases.
    Disease-a-month : DM, 2017, Volume: 63, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Asthma; Confusion; Cough; Female; Heart

2017
IL-1/inhibitory κB kinase ε-induced glycolysis augment epithelial effector function and promote allergic airways disease.
    The Journal of allergy and clinical immunology, 2018, Volume: 142, Issue:2

    Topics: Animals; Antigens, Dermatophagoides; Asthma; Cells, Cultured; Cohort Studies; Disease Models, Animal

2018
Urinary organic acids as biomarkers in the assessment of pulmonary function in children with asthma.
    Nutrition research (New York, N.Y.), 2019, Volume: 61

    Topics: Acids; Asthma; Biomarkers; Breath Tests; Child; Child, Preschool; Female; Forced Expiratory Volume;

2019
Acid-base patterns in acute severe asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2013, Volume: 50, Issue:10

    Topics: Acidosis, Respiratory; Acute Disease; Adult; Aged; Aged, 80 and over; Alkalosis, Respiratory; Asthma

2013
Therapeutic potential of biodegradable microparticles containing Punica granatum L. (pomegranate) in murine model of asthma.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models,

2013
Low-molecular-weight heparin (LMWH)-loaded large porous PEG-PLGA particles for the treatment of asthma.
    Journal of aerosol medicine and pulmonary drug delivery, 2014, Volume: 27, Issue:1

    Topics: Administration, Inhalation; Airway Remodeling; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Age

2014
Serum lactate increase during acute asthma treatment: a new piece of the puzzle.
    Chest, 2014, Volume: 145, Issue:1

    Topics: Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Lactic Acid; Male

2014
Salmeterol and lactic acidosis: clinical and educational aspects.
    CJEM, 2014, Volume: 16, Issue:1

    Topics: Acidosis, Lactic; Albuterol; Androstadienes; Asthma; Drug Overdose; Female; Humans; Intention; Lacti

2014
Too much testing?
    Chest, 2014, Volume: 145, Issue:6

    Topics: Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Lactic Acid; Male

2014
Response.
    Chest, 2014, Volume: 145, Issue:6

    Topics: Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Lactic Acid; Male

2014
Aerosolized montelukast polymeric particles-an alternative to oral montelukast-alleviate symptoms of asthma in a rodent model.
    Pharmaceutical research, 2014, Volume: 31, Issue:11

    Topics: Acetates; Aerosols; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveola

2014
Monitoring the ionic content of exhaled breath condensate in various respiratory diseases by capillary electrophoresis with contactless conductivity detection.
    Journal of breath research, 2015, May-06, Volume: 9, Issue:2

    Topics: Acetates; Adult; Aged; Ammonium Compounds; Asthma; Breath Tests; Butyrates; Calcium; Chlorides; Crow

2015
Reduced clot retraction rate and altered platelet energy production in patients with asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2016, Volume: 53, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Asthma; Blood Platelets; Case-Control Studies; Clot Retraction

2016
Getting Burned by Lactic Acid.
    Hospital pediatrics, 2016, Volume: 6, Issue:9

    Topics: Adolescent; Adrenergic beta-Agonists; Asthma; Humans; Hyperlactatemia; Lactic Acid; Male; Unnecessar

2016
Aerosolizable modified-release particles of montelukast improve retention and availability of the drug in the lungs.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jan-01, Volume: 96

    Topics: Acetates; Administration, Inhalation; Animals; Anti-Asthmatic Agents; Asthma; Biological Availabilit

2017
Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model.
    Cellular immunology, 2009, Volume: 260, Issue:1

    Topics: Animals; Asthma; Betamethasone; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Delivery

2009
Hyperlactic acidosis as metabolic side-effect of albuterol and theophylline in acute severe asthma.
    Klinische Padiatrie, 2010, Volume: 222, Issue:4

    Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Albuterol; Anti-Asthmatic Agents; Anti-Inf

2010
Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Feb-28, Volume: 150, Issue:1

    Topics: Animals; Asthma; Bicarbonates; Bronchodilator Agents; Budesonide; Drug Carriers; Female; Lactic Acid

2011
Effects of a Janus kinase inhibitor, pyridone 6, on airway responses in a murine model of asthma.
    Biochemical and biophysical research communications, 2011, Jan-07, Volume: 404, Issue:1

    Topics: Animals; Asthma; Benzimidazoles; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsules;

2011
Take my breath away: a case of lactic acidosis in an asthma exacerbation.
    CJEM, 2011, Volume: 13, Issue:4

    Topics: Acidosis, Lactic; Adult; Asthma; Diagnosis, Differential; Electrocardiography; Humans; Lactic Acid;

2011
The role of low-level lactate production in airway inflammation in asthma.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Feb-01, Volume: 302, Issue:3

    Topics: Adult; Aged; Animals; Asthma; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cytokines;

2012
Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone.
    CJEM, 2012, Volume: 14, Issue:6

    Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Albut

2012
[Influence of physical effort on concentration of lactic acid and acid-base equilibrium in patients with mild and moderate bronchial asthma].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 17, Issue:99

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Blood Gas Analysis; Carb

2004
Grave acidosis after severe anaphylactic bronchospasm: friend or foe?
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:4

    Topics: Acidosis; Adult; Anaphylaxis; Anti-Inflammatory Agents; Asthma; Blood Gas Analysis; Blood Glucose; B

2007
Hyperlactaemia due to nebulised salbutamol.
    Anaesthesia, 2007, Volume: 62, Issue:7

    Topics: Adult; Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Lactic Acid; Nebulizers and Vaporiz

2007
Hyperlactaemia in asthmatics.
    Anaesthesia, 2007, Volume: 62, Issue:10

    Topics: Albuterol; Asthma; Bronchodilator Agents; Humans; Lactic Acid

2007
Metabolic acidosis in severe asthma: Is it the disease or is it the doctor?
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007, Volume: 8, Issue:6

    Topics: Acidosis; Acute Disease; Albuterol; Asthma; Blood Gas Analysis; Bronchodilator Agents; Child, Presch

2007
[The effect of corticosteroid therapy and global respiratory insufficiency on lactate and amino acid levels in the blood].
    Medicinski arhiv, 1984, Volume: 38, Issue:3

    Topics: Amino Acids; Asthma; Humans; Lactates; Lactic Acid; Methylprednisolone; Respiratory Insufficiency

1984
Exercise-induced asthma - a comparison between two modes of exercise stress.
    European journal of respiratory diseases, 1981, Volume: 62, Issue:3

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Blood Gas Analysis; Female; Humans; Hydrogen-Ion Concentrat

1981
Effects of physical training on plasma citrate and exercise-induced asthma.
    Scandinavian journal of clinical and laboratory investigation, 1981, Volume: 41, Issue:3

    Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Blood Glucose; Child; Citrates; Citric Acid; Female; H

1981
Hyperlactatemia during acute severe asthma.
    Intensive care medicine, 1998, Volume: 24, Issue:4

    Topics: Acidosis, Lactic; Acute Disease; Adult; Arteries; Asthma; Blood Gas Analysis; Disease Progression; F

1998
Sensitivity of basophils to histamine releasing factor(s) of various origin: dependency on allergic phenotype of the donor and surface-bound IgE.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:1

    Topics: Asthma; Basophils; Biomarkers, Tumor; Bronchoalveolar Lavage Fluid; Histamine Release; Humans; Hyper

1990
The effect of endurance running training on asthmatic adults.
    British journal of sports medicine, 1989, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Cardiovascular System; Female; Forced Expirator

1989
Metabolic acidosis not due to lactic acidosis in patients with severe acute asthma.
    Critical care medicine, 1987, Volume: 15, Issue:12

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Adolescent; Adult; Aged; Asthma; Bicarbonates; Bl

1987
[Exercise, training and sports in children with asthma from the sports medicine viewpoint].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1985, Volume: 133, Issue:12

    Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Child; Child Development; Heart Rate; Humans; Lactates

1985