lactic acid has been researched along with Asphyxia Neonatorum in 64 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Asphyxia Neonatorum: Respiratory failure in the newborn. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether lactic acidosis at birth in asphyxiated neonates could predict the grade of EEG encephalopathy by examining the relationship between time taken for the normalisation of lactate, severity of encephalopathy and seizure burden." | 7.74 | Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden. ( Boylan, GB; Connolly, S; Fitzgerald, AP; Murphy, BP; Murray, DM; Ryan, CA, 2008) |
| " A randomized controlled study was designed to examine the dose-response effect of dobutamine (5-20 microg x kg(-1) x min(-1)) on systemic and regional circulations and oxygen metabolism in a neonatal swine model of hypoxia/reoxygenation." | 7.74 | The hemodynamic effects of dobutamine during reoxygenation after hypoxia: a dose-response study in newborn pigs. ( Abozaid, S; Al-Salam, Z; Bigam, D; Cheung, PY; Johnson, S, 2007) |
| "The possibility of detecting past hypoxia during the first 2 h after birth by means of blood analyses of hypoxanthine, lactate, base deficit, and pH was investigated in six infants with a 1 min Apgar score of less than or equal to 4." | 7.66 | Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH. ( Bratteby, LE; Swanström, S, 1982) |
| "To determine whether lactic acidosis at birth in asphyxiated neonates could predict the grade of EEG encephalopathy by examining the relationship between time taken for the normalisation of lactate, severity of encephalopathy and seizure burden." | 3.74 | Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden. ( Boylan, GB; Connolly, S; Fitzgerald, AP; Murphy, BP; Murray, DM; Ryan, CA, 2008) |
| " A randomized controlled study was designed to examine the dose-response effect of dobutamine (5-20 microg x kg(-1) x min(-1)) on systemic and regional circulations and oxygen metabolism in a neonatal swine model of hypoxia/reoxygenation." | 3.74 | The hemodynamic effects of dobutamine during reoxygenation after hypoxia: a dose-response study in newborn pigs. ( Abozaid, S; Al-Salam, Z; Bigam, D; Cheung, PY; Johnson, S, 2007) |
| " An increased lactate level was found in asphyctic infants and a clear correlation between lactic acidosis and foetal distress was documented." | 3.73 | Screening of foetal distress by assessment of umbilical cord lactate. ( Borruto, F; Comparetto, C; Treisser, A; Wegher, E, 2006) |
| "The possibility of detecting past hypoxia during the first 2 h after birth by means of blood analyses of hypoxanthine, lactate, base deficit, and pH was investigated in six infants with a 1 min Apgar score of less than or equal to 4." | 3.66 | Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH. ( Bratteby, LE; Swanström, S, 1982) |
| "Lactic acid and alanine were the primary metabolite predictors for the development of HIE, and when combined with clinical data, gave an area under the curve of 0." | 1.62 | Improvement in the Prediction of Neonatal Hypoxic-Ischemic Encephalopathy with the Integration of Umbilical Cord Metabolites and Current Clinical Makers. ( Boylan, GB; Broadhurst, DI; Dunn, WB; Hallberg, B; Kirwan, JA; Murray, DM; O'Boyle, DS; O'Neill, D, 2021) |
| " We examined the dose-response of milrinone on the intestinal circulation, oxygen metabolism, and injury in a newborn piglet model of asphyxia-reoxygenation." | 1.35 | Intestinal hemodynamic effects of milrinone in asphyxiated newborn pigs after reoxygenation with 100% oxygen: a dose-response study. ( Bigam, DL; Charrois, G; Cheung, PY; Jewell, LD; Joynt, C; Korbutt, G, 2009) |
| "The mean occlusion time until cardiac arrest was 14." | 1.31 | Reduced postnatal cerebral glucose metabolism measured by PET after asphyxia in near term fetal lambs. ( Hellström-Westas, L; Hernandez-Andrade, E; Ley, D; Lingman, G; Marsal, K; Ohlsson, T; Oskarsson, G; Pesonen, E; Sandell, A; Strand, SE; Thorngren-Jerneck, K; Werner, O, 2001) |
| "Hypoxic-ischemic encephalopathy did not develop in any of the normal newborns but did develop in 16 of the 40 newborns with asphyxia." | 1.30 | Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. ( Chang, YC; Huang, CC; Lin, KP; Wang, ST; Wu, PL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (7.81) | 18.7374 |
| 1990's | 17 (26.56) | 18.2507 |
| 2000's | 19 (29.69) | 29.6817 |
| 2010's | 21 (32.81) | 24.3611 |
| 2020's | 2 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bozkurt, O | 1 |
| Yucesoy, E | 1 |
| O'Boyle, DS | 1 |
| Dunn, WB | 1 |
| O'Neill, D | 1 |
| Kirwan, JA | 1 |
| Broadhurst, DI | 1 |
| Hallberg, B | 1 |
| Boylan, GB | 2 |
| Murray, DM | 2 |
| Solevåg, AL | 1 |
| Schmölzer, GM | 1 |
| Nakstad, B | 1 |
| Saugstad, OD | 2 |
| Cheung, PY | 4 |
| Polackova, R | 1 |
| Salounova, D | 1 |
| Kantor, L | 1 |
| Nakajima, J | 1 |
| Tsutsumi, N | 1 |
| Nara, S | 1 |
| Ishii, H | 1 |
| Suganami, Y | 1 |
| Sunohara, D | 1 |
| Kawashima, H | 1 |
| Chilinda, GK | 1 |
| Gadama, LA | 1 |
| Stones, W | 1 |
| Eriksen, VR | 1 |
| Trautner, S | 1 |
| Hahn, GH | 1 |
| Greisen, G | 1 |
| Pelletier, JS | 1 |
| LaBossiere, J | 1 |
| Dicken, B | 1 |
| Gill, RS | 1 |
| Sergi, C | 1 |
| Tahbaz, N | 1 |
| Bigam, D | 2 |
| Ujhazy, E | 1 |
| Dubovicky, M | 1 |
| Navarova, J | 1 |
| Sedlackova, N | 1 |
| Danihel, L | 1 |
| Brucknerova, I | 1 |
| Mach, M | 1 |
| Varkilova, L | 1 |
| Slancheva, B | 1 |
| Emilova, Z | 2 |
| Nikolov, A | 2 |
| Metodieva, V | 2 |
| Hitrova, S | 1 |
| Doicheva, E | 1 |
| Simović, AM | 1 |
| Kosutić, JLj | 1 |
| Prijić, SM | 1 |
| Knezević, JB | 1 |
| Vujić, AJ | 1 |
| Stojanović, ND | 1 |
| Surmiak, P | 1 |
| Baumert, M | 1 |
| Fiala, M | 1 |
| Sypniewska, K | 1 |
| Walencka, Z | 1 |
| Łukomska, A | 1 |
| Karcz, K | 1 |
| Robertson, NJ | 3 |
| Thayyil, S | 1 |
| Cady, EB | 2 |
| Raivich, G | 1 |
| Carbonne, B | 1 |
| Pons, K | 1 |
| Maisonneuve, E | 1 |
| Broad, KD | 1 |
| Fierens, I | 1 |
| Fleiss, B | 1 |
| Rocha-Ferreira, E | 1 |
| Ezzati, M | 1 |
| Hassell, J | 1 |
| Alonso-Alconada, D | 1 |
| Bainbridge, A | 2 |
| Kawano, G | 1 |
| Ma, D | 1 |
| Tachtsidis, I | 1 |
| Gressens, P | 1 |
| Golay, X | 1 |
| Sanders, RD | 1 |
| Azzopardi, D | 4 |
| Cady, E | 1 |
| Charles-Edwards, G | 1 |
| Deierl, A | 1 |
| Fagiolo, G | 1 |
| Franks, NP | 1 |
| Griffiths, J | 1 |
| Hajnal, J | 1 |
| Juszczak, E | 1 |
| Kapetanakis, B | 1 |
| Linsell, L | 1 |
| Maze, M | 1 |
| Omar, O | 1 |
| Strohm, B | 1 |
| Tusor, N | 1 |
| Edwards, AD | 3 |
| Sánchez-Illana, Á | 1 |
| Solberg, R | 1 |
| Lliso, I | 1 |
| Pankratov, L | 1 |
| Quintás, G | 1 |
| Vento, M | 2 |
| Kuligowski, J | 1 |
| Joynt, C | 1 |
| Bigam, DL | 1 |
| Charrois, G | 1 |
| Jewell, LD | 1 |
| Korbutt, G | 1 |
| Martin, RJ | 1 |
| Bookatz, GB | 1 |
| Gelfand, SL | 1 |
| Sastre, J | 1 |
| Arduini, A | 1 |
| Aguar, M | 1 |
| Escrig, R | 1 |
| Liu, L | 2 |
| Zheng, CX | 1 |
| Peng, SF | 1 |
| Zhou, HY | 2 |
| Su, ZY | 2 |
| He, L | 2 |
| Ai, T | 1 |
| Ramanah, R | 1 |
| Martin, A | 1 |
| Clement, MC | 1 |
| Maillet, R | 1 |
| Riethmuller, D | 1 |
| Araki, S | 1 |
| Takahashi, D | 1 |
| Matsui, M | 1 |
| Saito, R | 1 |
| Morita, H | 1 |
| Ishii, M | 1 |
| Senjyu, A | 1 |
| Morishita, T | 1 |
| Takano, S | 1 |
| Chiba, S | 1 |
| Mori, J | 1 |
| Kubo, K | 1 |
| Sato, H | 1 |
| Kawakami, A | 1 |
| Shimono, M | 1 |
| Shirahata, A | 1 |
| Kusuhara, K | 1 |
| Bennet, L | 2 |
| Booth, L | 1 |
| Gunn, AJ | 1 |
| Girard, N | 1 |
| White, CR | 1 |
| Mok, T | 1 |
| Doherty, DA | 1 |
| Henderson, JJ | 1 |
| Newnham, JP | 1 |
| Pennell, CE | 1 |
| Zarifi, MK | 1 |
| Astrakas, LG | 1 |
| Poussaint, TY | 1 |
| Plessis Ad, Ad | 1 |
| Zurakowski, D | 1 |
| Tzika, AA | 1 |
| Cappellini, M | 1 |
| Rapisardi, G | 1 |
| Cioni, ML | 1 |
| Fonda, C | 1 |
| VEDRA, B | 1 |
| ZNAMENACEK, K | 1 |
| PRIBYLOVA, H | 1 |
| Lin, JP | 1 |
| Vakrilova, L | 1 |
| Kalaĭdzhieva, M | 1 |
| Slŭncheva, B | 1 |
| Pramatarova, T | 1 |
| Khong, PL | 1 |
| Tse, C | 1 |
| Wong, IY | 1 |
| Lam, BC | 1 |
| Cheung, PT | 1 |
| Goh, WH | 1 |
| Kwong, NS | 1 |
| Ooi, GC | 1 |
| Brissaud, O | 1 |
| Chateil, JF | 1 |
| Bordessoules, M | 1 |
| Brun, M | 1 |
| Feng, ZW | 1 |
| Ojha, RK | 1 |
| Singh, SK | 1 |
| Batra, S | 1 |
| Sreenivas, V | 1 |
| Puliyel, JM | 1 |
| da Silva, LF | 1 |
| Höefel Filho, JR | 1 |
| Anés, M | 1 |
| Nunes, ML | 1 |
| Fitzgerald, AP | 1 |
| Ryan, CA | 1 |
| Murphy, BP | 1 |
| Connolly, S | 1 |
| Borruto, F | 1 |
| Comparetto, C | 1 |
| Wegher, E | 1 |
| Treisser, A | 1 |
| Al-Salam, Z | 1 |
| Johnson, S | 1 |
| Abozaid, S | 1 |
| Ruth, V | 1 |
| Raivio, KO | 1 |
| Swanström, S | 1 |
| Bratteby, LE | 1 |
| Edwards, D | 1 |
| Ma, S | 1 |
| Shieh, LI | 1 |
| Huang, CC | 2 |
| Frey, B | 1 |
| Pfenninger, J | 1 |
| Bachmann, D | 1 |
| Groenendaal, F | 1 |
| Veenhoven, RH | 1 |
| van der Grond, J | 1 |
| Jansen, GH | 1 |
| Witkamp, TD | 1 |
| de Vries, LS | 1 |
| Penrice, J | 1 |
| Lorek, A | 1 |
| Wylezinska, M | 1 |
| Amess, PN | 1 |
| Aldridge, RF | 1 |
| Stewart, A | 1 |
| Wyatt, JS | 1 |
| Reynolds, EO | 1 |
| Leth, H | 1 |
| Toft, PB | 1 |
| Peitersen, B | 1 |
| Lou, HC | 1 |
| Henriksen, O | 1 |
| Walker, V | 2 |
| Mills, GA | 2 |
| Green, LR | 1 |
| Gnanakumaran, K | 1 |
| Hanson, MA | 1 |
| Oriot, D | 2 |
| Nasimi, A | 1 |
| Berthier, M | 1 |
| Marlin, S | 1 |
| Hubert, A | 1 |
| Follet-Bouhamed, C | 1 |
| Hanrahan, JD | 2 |
| Cox, IJ | 2 |
| Cowan, FM | 2 |
| Sargentoni, J | 2 |
| Bell, JD | 2 |
| Bryant, DJ | 2 |
| Rutherford, MA | 1 |
| Nordström, L | 1 |
| Chua, S | 1 |
| Roy, A | 1 |
| Naka, K | 1 |
| Persson, B | 1 |
| Arulkumaran, S | 1 |
| Wang, ST | 1 |
| Chang, YC | 1 |
| Lin, KP | 1 |
| Wu, PL | 1 |
| Perlman, JM | 1 |
| Barkovich, AJ | 1 |
| Baranski, K | 1 |
| Vigneron, D | 1 |
| Partridge, JC | 1 |
| Hallam, DK | 1 |
| Hajnal, BL | 1 |
| Ferriero, DM | 1 |
| Pavlakis, SG | 1 |
| Kingsley, PB | 1 |
| Harper, R | 1 |
| Buckwald, S | 1 |
| Spinazzola, R | 1 |
| Frank, Y | 1 |
| Prohovnik, I | 1 |
| Park, WS | 1 |
| Chang, YS | 1 |
| Lee, M | 1 |
| Engidawork, E | 1 |
| Loidl, F | 1 |
| Chen, Y | 1 |
| Kohlhauser, C | 1 |
| Stoeckler, S | 1 |
| Dell'Anna, E | 1 |
| Lubec, B | 1 |
| Lubec, G | 1 |
| Goiny, M | 1 |
| Gross, J | 2 |
| Andersson, K | 1 |
| Herrera-Marschitz, M | 1 |
| Thorngren-Jerneck, K | 1 |
| Ley, D | 1 |
| Hellström-Westas, L | 1 |
| Hernandez-Andrade, E | 1 |
| Lingman, G | 1 |
| Ohlsson, T | 1 |
| Oskarsson, G | 1 |
| Pesonen, E | 1 |
| Sandell, A | 1 |
| Strand, SE | 1 |
| Werner, O | 1 |
| Marsal, K | 1 |
| Bauer, R | 1 |
| Brust, P | 1 |
| Walter, B | 1 |
| Vorwieger, G | 1 |
| Bergmann, R | 1 |
| Elhalag, E | 1 |
| Fritz, A | 1 |
| Steinbach, J | 1 |
| Füchtner, F | 1 |
| Hinz, R | 1 |
| Zwiener, U | 1 |
| Johannsen, B | 1 |
| Jurek, W | 1 |
| Szymczakiewicz-Multanowska, AM | 1 |
| Jurek, G | 1 |
| Bétrémieux, P | 1 |
| Baumann, N | 1 |
| Lefrançois, C | 1 |
| Le Marec, B | 1 |
| Jung, D | 1 |
| Lun, A | 1 |
| Zinsmeyer, J | 1 |
| Grauel, EL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimising the Duration of Cooling Therapy in Mild Neonatal Encephalopathy[NCT03409770] | 140 participants (Anticipated) | Interventional | 2019-10-10 | Active, not recruiting | |||
| Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia[NCT00934700] | 92 participants (Actual) | Interventional | 2012-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Fractional anisotropy (FA) is a measure of tissue integrity in white matter tracts measured by diffusion tensor MRI, and it has been used in work in animals to assess potential neuroprotectants and can be used to predict subsequent neurological outcomes after birth asphyxia, including in infants treated with moderate hypothermia.~It is a scalar value between 0-1 that describe anisotropy of a diffusion process. A value of zero means that diffusion is unrestricted (or equally restricted) in all directions. A value of one means that diffusion occurs only along one axis and is fully restricted along all other directions or similar.~Fractional anisotropy data were extracted froma mask of the posterior limb of the internal capsule via tract-based spatial statistics. *Coefficient of variation=√(exp(var)-1), where var is the variance on the log scale" (NCT00934700)
Timeframe: 10 days
| Intervention | units on a scale (Mean) |
|---|---|
| Combination of Hypothermia and Xenon | 0.40 |
| Hypothermia and Standard Intensive Care | 0.40 |
Cerebral Lac/NAA ratio measured by magnetic resonance spectroscopy in patents (NCT00934700)
Timeframe: 10 days
| Intervention | ratio (Geometric Mean) |
|---|---|
| Combination of Hypothermia and Xenon | 0.25 |
| Hypothermia and Standard Intensive Care | 0.28 |
5 reviews available for lactic acid and Asphyxia Neonatorum
| Article | Year |
|---|---|
Magnetic resonance spectroscopy biomarkers in term perinatal asphyxial encephalopathy: from neuropathological correlates to future clinical applications.
Topics: Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Biomarkers; Choline; Creatine; Diseas | 2014 |
Foetal scalp blood sampling during labour for pH and lactate measurements.
Topics: Acidosis; Asphyxia Neonatorum; Blood Specimen Collection; Cerebral Palsy; Female; Fetal Blood; Fetal | 2016 |
Potential biomarkers for hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Creatinine; Developmental Disabilities; Humans; Hypothermia, Induce | 2010 |
[Magnetic resonance spectroscopy for cerebral imaging].
Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea | 2010 |
Magnetic resonance spectroscopy in neonates.
Topics: Adult; Aspartic Acid; Asphyxia Neonatorum; Brain; Energy Metabolism; Humans; Infant; Infant, Newborn | 1995 |
5 trials available for lactic acid and Asphyxia Neonatorum
| Article | Year |
|---|---|
Lactate acidosis and cardiac output during initial therapeutic cooling in asphyxiated newborn infants.
Topics: Acidosis, Lactic; Asphyxia Neonatorum; Cardiac Output; Female; Humans; Hypothermia, Induced; Infant, | 2019 |
Umbilical cord blood NGAL concentration as an early marker of perinatal asphyxia in neonates.
Topics: Acute-Phase Proteins; Asphyxia Neonatorum; Biomarkers; Child; Creatinine; Female; Fetal Blood; Gesta | 2014 |
Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial.
Topics: Acidosis; Anesthetics, Inhalation; Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Combined Modalit | 2016 |
The effect of time, temperature and storage device on umbilical cord blood gas and lactate measurement: a randomized controlled trial.
Topics: Apgar Score; Asphyxia Neonatorum; Blood Chemical Analysis; Blood Gas Analysis; Delivery, Obstetric; | 2012 |
Prognostic value of 1H-MRS in neonatal encephalopathy.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatine; Creatinine; Femal | 2006 |
54 other studies available for lactic acid and Asphyxia Neonatorum
| Article | Year |
|---|---|
Acute Kidney Injury in Neonates with Perinatal Asphyxia Receiving Therapeutic Hypothermia.
Topics: Acute Kidney Injury; Asphyxia Neonatorum; Biomarkers; Female; Fetal Blood; Humans; Hydrogen-Ion Conc | 2021 |
Improvement in the Prediction of Neonatal Hypoxic-Ischemic Encephalopathy with the Integration of Umbilical Cord Metabolites and Current Clinical Makers.
Topics: Alanine; Apgar Score; Asphyxia Neonatorum; Biomarkers; Case-Control Studies; Electroencephalography; | 2021 |
Association between Brain and Kidney Near-Infrared Spectroscopy and Early Postresuscitation Mortality in Asphyxiated Newborn Piglets.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Pressure; Brain; Cardiac Output; Cardiopulmona | 2017 |
Lactate as an early predictor of psychomotor development in neonates with asphyxia receiving therapeutic hypothermia.
Topics: Asphyxia Neonatorum; Biomarkers; Child, Preschool; Female; Humans; Hypothermia, Induced; Infant, New | 2018 |
Correlations of Enzyme Levels at Birth in Stressed Neonates with Short-Term Outcomes.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Asphyxia Neonatorum; Creatine Kinase; Female; Hum | 2018 |
Point-of-care umbilical arterial lactate and newborn outcomes in a low resource setting: cohort study.
Topics: Adult; Apgar Score; Asphyxia Neonatorum; Cohort Studies; Female; Humans; Infant, Newborn; Lactic Aci | 2018 |
Low-dose vasopressin improves cardiac function in newborn piglets with acute hypoxia-reoxygenation.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cardiac Output; Dobutamine; Glutathione; Heart Ventr | 2013 |
Subchronic perinatal asphyxia in rats: embryo-foetal assessment of a new model of oxidative stress during critical period of development.
Topics: Animals; Asphyxia Neonatorum; Disease Models, Animal; Female; Glucose; Lactic Acid; Oxidative Stress | 2013 |
[Blood lactate measurments as a diagnostic and prognostic tool after birth asphyxia in newborn infants with gestational age > or = 34 gestational weeks].
Topics: Asphyxia Neonatorum; Female; Follow-Up Studies; Gestational Age; Humans; Hydrogen-Ion Concentration; | 2013 |
The role of biochemical markers as early indicators of cardiac damage and prognostic parameters of perinatal asphyxia.
Topics: Asphyxia Neonatorum; Biomarkers; C-Reactive Protein; Creatine Kinase, MB Form; Heart Failure; Humans | 2014 |
Inhaled 45-50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia.
Topics: Animals; Animals, Newborn; Argon; Aspartic Acid; Asphyxia Neonatorum; Blood Chemical Analysis; Blood | 2016 |
Assessment of phospholipid synthesis related biomarkers for perinatal asphyxia: a piglet study.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Biomarkers; Choline; Female; Humans; Hypoxia-Ischemi | 2017 |
Intestinal hemodynamic effects of milrinone in asphyxiated newborn pigs after reoxygenation with 100% oxygen: a dose-response study.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cardiotonic Agents; Dose-Response Relationship, Drug | 2009 |
Consequences of neonatal resuscitation with supplemental oxygen.
Topics: Animals; Asphyxia Neonatorum; Glutathione; Humans; Infant, Newborn; Infant, Premature; Infant, Prema | 2008 |
Evaluation of urinary S100B protein level and lactate/creatinine ratio for early diagnosis and prognostic prediction of neonatal hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Child Development; Creatinine; Developmental Disabilities; Humans; | 2010 |
Fetal scalp lactate microsampling for non-reassuring fetal status during labor: a prospective observational study.
Topics: Adult; Asphyxia Neonatorum; Female; Heart Rate, Fetal; Humans; Hydrogen-Ion Concentration; Infant, N | 2010 |
[Brain hypothermia therapy for newborns with severe birth asphyxia: an experience from a single neonatal intensive care unit].
Topics: Asphyxia Neonatorum; Brain; Humans; Hypothermia, Induced; Infant, Low Birth Weight; Infant, Newborn; | 2010 |
Prediction of adverse outcome with cerebral lactate level and apparent diffusion coefficient in infants with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Brain; Brain Chemistry; Choline; Female; Humans; Infant, Newborn; Lactic Acid; | 2002 |
Acute hypoxic encephalopathy in the full-term newborn: correlation between Magnetic Resonance Spectroscopy and neurological evaluation at short and long term.
Topics: Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatinine; Humans; Hypoxia, Brain; Infa | 2002 |
OXYGEN AND LACTATE LEVELS IN THE UMBILICAL VEIN BLOOD OF NORMAL AND ASPHYXIATED NEWBORN INFANTS.
Topics: Acid-Base Equilibrium; Asphyxia Neonatorum; Blood Chemical Analysis; Blood Gas Analysis; Female; Fet | 1964 |
THE SIGNIFICANCE OF BLOOD "EXCESS LACTATE" IN THE NEWBORN PERIOD.
Topics: Asphyxia Neonatorum; Biomedical Research; Blood Glucose; Carbohydrate Metabolism; Cesarean Section; | 1964 |
The acidosis paradox: asphyxial brain injury without coincident acidemia.
Topics: Acidosis; Apgar Score; Asphyxia Neonatorum; Brain Injury, Chronic; Gestational Age; Humans; Infant, | 2004 |
[The significance of parameters of the acid-base status, blood gas and blood lactate level for the adequate resuscitation and prognosis in newborns with very low birth weight].
Topics: Acid-Base Equilibrium; Asphyxia Neonatorum; Blood Gas Analysis; Humans; Infant, Low Birth Weight; In | 2004 |
Diffusion-weighted imaging and proton magnetic resonance spectroscopy in perinatal hypoxic-ischemic encephalopathy: association with neuromotor outcome at 18 months of age.
Topics: Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Brain; Choline; Creatine; Diffusion Magnetic Reso | 2004 |
Chemical shift imaging and localised magnetic resonance spectroscopy in full-term asphyxiated neonates.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Brain; Choline; Creatine; Electroencephalography; F | 2005 |
[Urinary S100B protein and lactate/creatinine ratio measurements: a tool for the early identification of neonatal hypoxic-ischemic encephalopathy].
Topics: Apgar Score; Asphyxia Neonatorum; Creatinine; Early Diagnosis; Female; Humans; Hypoxia-Ischemia, Bra | 2005 |
Lactate: creatinine ratio in babies with thin meconium staining of amniotic fluid.
Topics: Amniotic Fluid; Apgar Score; Asphyxia Neonatorum; Creatinine; Female; Gestational Age; Humans; Hypox | 2006 |
Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden.
Topics: Acidosis, Lactic; Asphyxia Neonatorum; Electroencephalography; Female; Humans; Hypoxia-Ischemia, Bra | 2008 |
Screening of foetal distress by assessment of umbilical cord lactate.
Topics: Acidosis, Lactic; Asphyxia Neonatorum; Biomarkers; Female; Fetal Blood; Fetal Distress; Humans; Infa | 2006 |
The hemodynamic effects of dobutamine during reoxygenation after hypoxia: a dose-response study in newborn pigs.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Pressure; Cardiac Output; Dobutamine; Dose-Res | 2007 |
Purine metabolites and lactate as parameters of hypoxia in the newborn infant.
Topics: Asphyxia Neonatorum; Humans; Hypoxanthines; Hypoxia; Infant, Newborn; Lactates; Lactic Acid; Purines | 1984 |
Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH.
Topics: Acid-Base Imbalance; Asphyxia Neonatorum; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxant | 1982 |
High-resolution proton nuclear magnetic resonance studies of urine from asphyxiated newborn infants.
Topics: Asphyxia Neonatorum; Citrates; Citric Acid; Humans; Infant, Newborn; Ketoglutaric Acids; Lactates; L | 1995 |
Prognostic value of hyperlactatemia in neonates.
Topics: Asphyxia Neonatorum; Humans; Infant, Newborn; Lactates; Lactic Acid; Predictive Value of Tests; Prog | 1995 |
Cerebral lactate and N-acetyl-aspartate/choline ratios in asphyxiated full-term neonates demonstrated in vivo using proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Asphyxia Neonatorum; Brain; Choline; Humans; Infant; Infant, Newborn; Lactates; Lacti | 1994 |
Proton magnetic resonance spectroscopy of the brain in normal preterm and term infants, and early changes after perinatal hypoxia-ischemia.
Topics: Asphyxia Neonatorum; Brain; Brain Ischemia; Case-Control Studies; Humans; Hypoxia, Brain; Infant, Ne | 1996 |
Use of brain lactate levels to predict outcome after perinatal asphyxia.
Topics: Asphyxia Neonatorum; Brain Chemistry; Brain Damage, Chronic; Cerebral Palsy; Cerebrovascular Circula | 1996 |
Effects of hypoxia on urinary organic acid and hypoxanthine excretion in fetal sheep.
Topics: Animals; Asphyxia Neonatorum; Blood Gas Analysis; Blood Pressure; Carboxylic Acids; Disease Models, | 1996 |
Lactate and anion gap in asphyxiated neonates.
Topics: Acid-Base Equilibrium; Asphyxia Neonatorum; Humans; Infant, Newborn; Lactic Acid; Retrospective Stud | 1998 |
Persistent increases in cerebral lactate concentration after birth asphyxia.
Topics: Asphyxia Neonatorum; Brain; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; P | 1998 |
Lactate, lactate/pyruvate ratio and catecholamine interrelations in cord blood at delivery in complicated pregnancies.
Topics: Asphyxia Neonatorum; Catecholamines; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; | 1998 |
Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age.
Topics: Asphyxia Neonatorum; Brain; Brain Damage, Chronic; Creatine; Female; Humans; Image Processing, Compu | 1999 |
Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Brain Ischemia; Creatinine; Developmental Disabilities; Fetal Hypox | 1999 |
Markers of asphyxia and neonatal brain injury.
Topics: Asphyxia Neonatorum; Biomarkers; Brain Ischemia; Creatinine; Fetal Hypoxia; Humans; Hypoxia, Brain; | 1999 |
Proton MR spectroscopy for the evaluation of brain injury in asphyxiated, term neonates.
Topics: Aspartic Acid; Asphyxia Neonatorum; Brain; Brain Damage, Chronic; Choline; Creatine; Developmental D | 1999 |
Correlation of basal ganglia magnetic resonance spectroscopy with Apgar score in perinatal asphyxia.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Cerebral Palsy; Choline; Humans; Inf | 1999 |
Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation-reperfusion period after acute transient global hypoxia-ischemia in the newborn piglet.
Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Gas Analysis; Blood | 2001 |
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Ani | 2001 |
Reduced postnatal cerebral glucose metabolism measured by PET after asphyxia in near term fetal lambs.
Topics: Acidosis; Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Pressure; Cerebral Cortex; Cerebrova | 2001 |
Effect of hypoxia/hypercapnia on metabolism of 6-[(18)F]fluoro-L-DOPA in newborn piglets.
Topics: Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Asphyxia Neonatorum; Brain; Cardiov | 2002 |
[Umbilical artery lactate level as a marker of the neonatal clinical condition--preliminary results].
Topics: Asphyxia Neonatorum; Biomarkers; Fetal Blood; Humans; Infant, Newborn; Lactic Acid; Prognosis; Prosp | 2001 |
CSF ascorbic acid and lactate levels after neonatal asphyxia: preliminary results.
Topics: Ascorbic Acid; Asphyxia Neonatorum; Brain Ischemia; France; Hospitals, University; Humans; Infant, N | 1992 |
Effects of birth asphyxia on urinary organic acid excretion.
Topics: 3-Hydroxybutyric Acid; Acids; Aconitic Acid; Apgar Score; Asphyxia Neonatorum; Creatinine; Fetal Dis | 1992 |
The concentration of hypoxanthine and lactate in the blood of healthy and hypoxic newborns.
Topics: Acid-Base Equilibrium; Apgar Score; Asphyxia Neonatorum; Humans; Hypoxanthine; Hypoxanthines; Hypoxi | 1985 |