Page last updated: 2024-10-17

lactic acid and Arthritis

lactic acid has been researched along with Arthritis in 26 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
"Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis."7.69Synovial fluid L-lactic acid in acute arthritis of the adult knee joint. ( Aro, HT; Kortekangas, P; Peltola, O; Toivanen, A, 1995)
"Lactic acid was found to be a useful and rapid test for differentiating between septic and non-septic arthritis being markedly raised (greater than 12 mmol/l) in all the septic joints."5.26Synovial fluid lactic acid measurement in the diagnosis and management of septic arthritis. ( Doyle, D; Riordan, T; Tabaqchali, S, 1982)
" The aim of this study was to evaluate the outcome of revision MCP arthroplasty using poly-L/D-lactic acid 96:4 (PLDLA) interposition implant and morcelised allograft or autograft bone packing in patients with failed MCP arthroplasties and severe osteolysis."5.16The mean seven years' results of the use of poly-L/D-lactic acid (PLDLA) interposition implant and bone packing in revision metacarpophalangeal arthroplasty: a prospective cohort study. ( Belt, EA; Honkanen, PB; Ikävalko, M; Skyttä, ET; Tiihonen, R, 2012)
", samples with HMGB-1 levels >2 SD above the mean level in samples from patients with noninflammatory arthropathy), concentrations of HMGB-1 were significantly correlated with those of lactic acid, a marker of tissue hypoxia."3.74Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis. ( Abeyama, K; Fukuda, T; Fukuzaki, K; Hamada, T; Hashiguchi, K; Horai, N; Komiya, S; Kuwazuru, A; Maruyama, I; Nagata, R; Nagayama, S; Sunahara, N; Tanaka, M; Torikai, M; Yamada, S, 2008)
"To analyze the usefulness of D-lactic acid levels in synovial fluid (SF) as a rapid test to support the early diagnosis of bacterial arthritis (BA)."3.69D-lactic acid in synovial fluid. A rapid diagnostic test for bacterial synovitis. ( Brancós, MA; Collado, A; Gratacós, J; Jimenez de Anta, MT; Marcos, MA; Moyá, F; Muñoz-Gómez, J; Sanmartí, R; Vila, J, 1995)
"Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis."3.69Synovial fluid L-lactic acid in acute arthritis of the adult knee joint. ( Aro, HT; Kortekangas, P; Peltola, O; Toivanen, A, 1995)
"The concentration of lactic acid in synovial fluid was estimated in 43 specimens from patients with an acute monoarthritis by a simple enzyme method."3.66Lactate UV-system: a rapid method for diagnosis of septic arthritis. ( Behn, AR; Mathews, JA; Phillips, I, 1981)
"Lactic acid was found to be a useful and rapid test for differentiating between septic and non-septic arthritis being markedly raised (greater than 12 mmol/l) in all the septic joints."1.26Synovial fluid lactic acid measurement in the diagnosis and management of septic arthritis. ( Doyle, D; Riordan, T; Tabaqchali, S, 1982)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's6 (23.08)18.2507
2000's4 (15.38)29.6817
2010's5 (19.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Proot, JL1
de Vicente, F1
Sheahan, DE1
Wu, G1
Wang, L1
Li, H1
Ke, Y1
Yao, Y1
Hamada, T1
Torikai, M1
Kuwazuru, A1
Tanaka, M1
Horai, N1
Fukuda, T2
Yamada, S1
Nagayama, S1
Hashiguchi, K1
Sunahara, N1
Fukuzaki, K1
Nagata, R1
Komiya, S1
Maruyama, I1
Abeyama, K1
NICHOLSON, DP1
Butoescu, N1
Seemayer, CA1
Foti, M1
Jordan, O1
Doelker, E1
RAFF, A1
Khaled, KA1
Sarhan, HA1
Ibrahim, MA1
Ali, AH1
Naguib, YW1
Fuchs, K1
Kukuk, D1
Reischl, G1
Föller, M1
Eichner, M1
Reutershan, J1
Lang, F1
Röcken, M1
Pichler, BJ1
Kneilling, M1
Tiihonen, R1
Honkanen, PB1
Belt, EA1
Ikävalko, M1
Skyttä, ET1
LAWRENCE, JS1
WAUGH, WG1
KALLIOMAKI, JL1
PULKKINEN, M1
SAVOLA, P1
DIMEZZA, F1
SØNDER, P1
Mavridis, AK1
Drosos, AA1
Tsolas, O1
Moutsopoulos, HM1
Gobelet, C1
Gerster, JC1
Riordan, T1
Doyle, D1
Tabaqchali, S1
Behn, AR1
Mathews, JA1
Phillips, I1
Gratacós, J1
Vila, J1
Moyá, F1
Marcos, MA1
Collado, A1
Sanmartí, R1
Brancós, MA1
Jimenez de Anta, MT1
Muñoz-Gómez, J1
Kortekangas, P1
Peltola, O1
Toivanen, A1
Aro, HT1
James, MJ1
Cleland, LG1
Gaffney, RD1
Proudman, SM1
Chatterton, BE1
Eliaz, R1
Wallach, D1
Kost, J1
Herz, H1
Blake, DR1
Grootveld, M1
Takizawa, T1
Akizuki, S1
Horiuchi, H1
Yasukawa, Y1
Tunçay, M1
Caliş, S1
Kaş, HS1
Ercan, MT1
Peksoy, I1
Hincal, AA1
Kraus, VB1
Huebner, JL1
Fink, C1
King, JB1
Brown, S1
Vail, TP1
Guilak, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Mild, Moderate and Severe Osteoarthritis of the Knee[NCT03100799]30 participants (Actual)Interventional2017-03-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lactic acid and Arthritis

ArticleYear
The mean seven years' results of the use of poly-L/D-lactic acid (PLDLA) interposition implant and bone packing in revision metacarpophalangeal arthroplasty: a prospective cohort study.
    Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 2012, Volume: 101, Issue:4

    Topics: Arthritis; Arthroplasty, Replacement; Bone Transplantation; Female; Follow-Up Studies; Humans; Joint

2012

Other Studies

25 other studies available for lactic acid and Arthritis

ArticleYear
Analysis of lactate concentrations in canine synovial fluid.
    Veterinary and comparative orthopaedics and traumatology : V.C.O.T, 2015, Volume: 28, Issue:5

    Topics: Animals; Arthritis; Arthritis, Infectious; Case-Control Studies; Cell Count; Dog Diseases; Dogs; Fem

2015
Function of sustained released resveratrol on IL-1β-induced hBMSC MMP13 secretion inhibition and chondrogenic differentiation promotion.
    Journal of biomaterials applications, 2016, Volume: 30, Issue:7

    Topics: Antioxidants; Arthritis; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; C

2016
Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis.
    Arthritis and rheumatism, 2008, Volume: 58, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arthritis; Arthritis, Experimental; Blotting, Western; Cell

2008
The treatment of osteo-arthritis with procaine lactic acid.
    Annals of the rheumatic diseases, 1948, Volume: 7, Issue:1

    Topics: Arthritis; Lactic Acid; Osteoarthritis; Procaine

1948
Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis.
    Biomaterials, 2009, Volume: 30, Issue:9

    Topics: Animals; Arthritis; Cell Survival; Cells, Cultured; Cytochalasin D; Dexamethasone; Drug Carriers; En

2009
The Sunderland Infirmary new drug for arthritis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1947, May-24, Volume: 21, Issue:10

    Topics: Arthritis; Humans; Lactic Acid

1947
Prednisolone-loaded PLGA microspheres. in vitro characterization and in vivo application in adjuvant-induced arthritis in mice.
    AAPS PharmSciTech, 2010, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Capsules; Diffusion; Drug Carriers; Drug Compounding;

2010
Oxygen breathing affects 3'-deoxy-3'-18F-fluorothymidine uptake in mouse models of arthritis and cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:5

    Topics: Anesthesia; Animals; Ankle; Arthritis; Artifacts; Biological Transport; Carbon Dioxide; Cell Line, T

2012
Lactic acid in the treatment of osteo-arthritis.
    Lancet (London, England), 1953, Oct-31, Volume: 265, Issue:6792

    Topics: Arthritis; Lactic Acid; Osteoarthritis

1953
Lactic acid in the treatment of osteo-arthritis.
    Lancet (London, England), 1953, Nov-21, Volume: 265, Issue:6795

    Topics: Arthritis; Lactic Acid; Osteoarthritis

1953
Lactic acid response to muscular exercise in rheumatoid arthritis.
    Annales medicinae experimentalis et biologiae Fenniae, 1957, Volume: 35, Issue:4

    Topics: Arthritis; Arthritis, Rheumatoid; Exercise; Humans; Lactic Acid; Muscles

1957
[STUDY OF LACTATE AND MALATE DEHYDROGENASES IN SYNOVIA OF PATIENTS WITH POST-TRAUMATIC JOINT DISEASE].
    Gazzetta internazionale di medicina e chirurgia, 1964, Dec-15, Volume: 68

    Topics: Arthritis; Humans; Joint Diseases; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Malate Dehydrogen

1964
[Lactic acid therapy of arthrosis].
    Ugeskrift for laeger, 1950, Jul-27, Volume: 112, Issue:30

    Topics: Arthritis; Humans; Joint Diseases; Lactic Acid; Osteoarthritis

1950
Lactate levels in Brucella arthritis.
    Rheumatology international, 1984, Volume: 4, Issue:4

    Topics: Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Brucellosis; Gout; Humans; Lactates; Lactic

1984
Synovial fluid lactate levels in septic and non-septic arthritides.
    Annals of the rheumatic diseases, 1984, Volume: 43, Issue:5

    Topics: Arthritis; Arthritis, Infectious; Arthritis, Reactive; Arthritis, Rheumatoid; Gonorrhea; Hemarthrosi

1984
Synovial fluid lactic acid measurement in the diagnosis and management of septic arthritis.
    Journal of clinical pathology, 1982, Volume: 35, Issue:4

    Topics: Arthritis; Arthritis, Infectious; Diagnosis, Differential; Flame Ionization; Humans; L-Lactate Dehyd

1982
Lactate UV-system: a rapid method for diagnosis of septic arthritis.
    Annals of the rheumatic diseases, 1981, Volume: 40, Issue:5

    Topics: Acute Disease; Adult; Aged; Arthritis; Arthritis, Infectious; Diagnosis, Differential; Female; Human

1981
D-lactic acid in synovial fluid. A rapid diagnostic test for bacterial synovitis.
    The Journal of rheumatology, 1995, Volume: 22, Issue:8

    Topics: Arthritis; Arthritis, Infectious; Biomarkers; Gentian Violet; Humans; Lactates; Lactic Acid; Leukocy

1995
Synovial fluid L-lactic acid in acute arthritis of the adult knee joint.
    Scandinavian journal of rheumatology, 1995, Volume: 24, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Arthritis; Arthritis, Infectious; Bacterial Infections; Fema

1995
Effect of exercise on 99mTc-DTPA clearance from knees with effusions.
    The Journal of rheumatology, 1994, Volume: 21, Issue:3

    Topics: Arthritis; Bicycling; Exudates and Transudates; Humans; Ischemia; Knee Joint; Lactates; Lactic Acid;

1994
Long-term protection against the effects of tumour necrosis factor by controlled delivery of the soluble p55 TNF receptor.
    Cytokine, 1996, Volume: 8, Issue:6

    Topics: Animals; Antigens, CD; Arthritis; Biocompatible Materials; Cachexia; Delayed-Action Preparations; Hu

1996
Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases.
    Free radical research, 1997, Volume: 26, Issue:1

    Topics: Adult; Aged; Arthritis; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical

1997
Foreign body gonitis caused by a broken poly-L-lactic acid screw.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 1998, Volume: 14, Issue:3

    Topics: Adult; Arthritis; Arthroscopy; Bone Screws; Equipment Failure; Foreign-Body Reaction; Humans; Knee J

1998
Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation.
    International journal of pharmaceutics, 2000, Feb-15, Volume: 195, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biocompatible Materials; Biodegradation

2000
Urea as a passive transport marker for arthritis biomarker studies.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:2

    Topics: Animals; Arthritis; Biological Transport; Biomarkers; Cartilage; Cartilage Oligomeric Matrix Protein

2002