lactic acid has been researched along with Anoxia, Brain in 96 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Authors examined 34 patients with traumatic intracranial hematomas including 19 patients who died during the first two weeks after admission to the hospital and 15 patients who were discharged for outpatient treatment." | 1.42 | [A role of stress-induced neuroendocrine disorders and tissue hypoxia in the thanatogenesis of traumatic intracranial hematomas]. ( Kravtsov, YI; Kravtsova, EY; Shevchenko, KV, 2015) |
| "Cerebral ischemia was assumed when neurologic deterioration occurred." | 1.35 | The accuracy of jugular bulb venous monitoring in detecting cerebral ischemia in awake patients undergoing carotid endarterectomy. ( Kasprzak, P; Metz, C; Moritz, S; Taeger, K; Woertgen, C, 2008) |
| "During brain anoxia or ischemia, a decrease in the level of ATP leads to a sudden decrease in transmembrane ion gradients [anoxic depolarization (AD)]." | 1.33 | A preferential role for glycolysis in preventing the anoxic depolarization of rat hippocampal area CA1 pyramidal cells. ( Allen, NJ; Attwell, D; Káradóttir, R, 2005) |
| "After cardiac resuscitation, hypoxic encephalopathy often is the limiting factor regarding outcome due to the oxygen sensitivity of the brain." | 1.32 | Neurochemical monitoring using intracerebral microdialysis during cardiac resuscitation. ( Barbach, J; Bauer, R; Gabl, M; Galiano, K; Mohsenipour, I; Obwegeser, A, 2004) |
| "The theophylline infusion was begun 30 min prior to and ended 30 min after the completion of the hypoxic insult." | 1.31 | The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep. ( Blood, AB; Hunter, CJ; Power, GG, 2002) |
| "Hypoxic-ischemic encephalopathy did not develop in any of the normal newborns but did develop in 16 of the 40 newborns with asphyxia." | 1.30 | Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. ( Chang, YC; Huang, CC; Lin, KP; Wang, ST; Wu, PL, 1999) |
| "Following prolonged cardiac arrest, reperfusion of the brain is endangered by the low blood perfusion pressure during the early resuscitation phase." | 1.28 | Two-stage resuscitation of the cat brain after prolonged cardiac arrest. ( Hossmann, KA; Ishimaru, S; Seo, K, 1991) |
| " Since the vascular type of primary dementia is found to be associated with metabolic variations which resemble that of a cerebral hypoxia, hypoxic brain damage was produced by means of a sublethal dosage of cyanide in two-year-old rats." | 1.27 | The effect of naftidrofuryl on cyanide-induced hypoxic damage to glucose and energy metabolism in brain cortex of rats. ( Hoyer, S, 1984) |
| "Unilateral cerebral hypoxia-oligemia was produced in anesthetized mice using carotid artery occlusion combined with systemic hypoxia (10% O2)." | 1.27 | Effect of glucose on recovery of energy metabolism following hypoxia-oligemia in mouse brain: dose-dependence and carbohydrate specificity. ( McKee, AE; Sims, RE; Welsh, FA, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (19.79) | 18.7374 |
| 1990's | 25 (26.04) | 18.2507 |
| 2000's | 30 (31.25) | 29.6817 |
| 2010's | 20 (20.83) | 24.3611 |
| 2020's | 2 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| Letson, HL | 1 |
| Granfeldt, A | 1 |
| Jensen, TH | 1 |
| Mattson, TH | 1 |
| Dobson, GP | 1 |
| Ribeiro, MC | 1 |
| Bezerra, TDS | 1 |
| Soares, AC | 1 |
| Boechat-Ramos, R | 1 |
| Carneiro, FP | 1 |
| Vianna, LMS | 1 |
| Faro, LRF | 1 |
| Silva, MVD | 1 |
| Vieira, MP | 1 |
| Monteiro, IO | 1 |
| Ferreira, VM | 1 |
| Vestergaard, MB | 1 |
| Jensen, ML | 1 |
| Arngrim, N | 1 |
| Lindberg, U | 1 |
| Larsson, HB | 1 |
| Rass, V | 1 |
| Solari, D | 1 |
| Ianosi, B | 1 |
| Gaasch, M | 1 |
| Kofler, M | 1 |
| Schiefecker, AJ | 1 |
| Miroz, JP | 1 |
| Morelli, P | 1 |
| Thomé, C | 1 |
| Beer, R | 1 |
| Pfausler, B | 1 |
| Oddo, M | 2 |
| Helbok, R | 1 |
| Sala, N | 1 |
| Suys, T | 1 |
| Zerlauth, JB | 1 |
| Bouzat, P | 1 |
| Messerer, M | 1 |
| Bloch, J | 1 |
| Levivier, M | 1 |
| Magistretti, PJ | 1 |
| Meuli, R | 1 |
| Pattarini, JM | 1 |
| Blue, RS | 1 |
| Aikins, LT | 1 |
| Law, J | 1 |
| Walshe, AD | 1 |
| Garbino, A | 1 |
| Turney, MW | 1 |
| Clark, JB | 1 |
| Czech-Damal, NU | 1 |
| Geiseler, SJ | 1 |
| Hoff, ML | 1 |
| Schliep, R | 1 |
| Ramirez, JM | 1 |
| Folkow, LP | 1 |
| Burmester, T | 1 |
| Ryu, JA | 1 |
| Cho, YH | 1 |
| Sung, K | 1 |
| Choi, SH | 1 |
| Yang, JH | 2 |
| Choi, JH | 1 |
| Lee, DS | 1 |
| Castillo, X | 1 |
| Rosafio, K | 1 |
| Wyss, MT | 1 |
| Drandarov, K | 1 |
| Buck, A | 1 |
| Pellerin, L | 1 |
| Weber, B | 1 |
| Hirt, L | 1 |
| Kravtsov, YI | 1 |
| Shevchenko, KV | 1 |
| Kravtsova, EY | 1 |
| Karagiannis, A | 1 |
| Sylantyev, S | 1 |
| Hadjihambi, A | 1 |
| Hosford, PS | 1 |
| Kasparov, S | 1 |
| Gourine, AV | 1 |
| Sánchez-Illana, Á | 1 |
| Solberg, R | 1 |
| Lliso, I | 1 |
| Pankratov, L | 1 |
| Quintás, G | 1 |
| Saugstad, OD | 1 |
| Vento, M | 1 |
| Kuligowski, J | 1 |
| Nucci-da-Silva, MP | 1 |
| Amaro, E | 1 |
| Charles-Edwards, GD | 1 |
| Jan, W | 1 |
| To, M | 1 |
| Maxwell, D | 1 |
| Keevil, SF | 1 |
| Robinson, R | 1 |
| Rasmussen, P | 1 |
| Nielsen, J | 1 |
| Overgaard, M | 1 |
| Krogh-Madsen, R | 1 |
| Gjedde, A | 1 |
| Secher, NH | 1 |
| Petersen, NC | 1 |
| Liu, JQ | 1 |
| Lee, TF | 1 |
| Chen, C | 1 |
| Bagim, DL | 1 |
| Cheung, PY | 1 |
| Girard, N | 1 |
| Merino, MA | 1 |
| Sahuquillo, J | 1 |
| Borrull, A | 1 |
| Poca, MA | 1 |
| Riveiro, M | 1 |
| Expósito, L | 1 |
| Hellewell, SC | 1 |
| Yan, EB | 1 |
| Agyapomaa, DA | 1 |
| Bye, N | 1 |
| Morganti-Kossmann, MC | 1 |
| Pfeil, A | 2 |
| Pfeifer, R | 1 |
| Böttcher, J | 1 |
| Neumann, R | 1 |
| Axer, H | 1 |
| Schmidt, P | 1 |
| Herzog, A | 1 |
| Kaiser, WA | 1 |
| Wolf, G | 1 |
| Hansch, A | 1 |
| Chen, H | 1 |
| Spagnoli, F | 1 |
| Burris, M | 1 |
| Rolland, WB | 1 |
| Fajilan, A | 1 |
| Dou, H | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Harris, AD | 1 |
| Roberton, VH | 1 |
| Huckle, DL | 1 |
| Saxena, N | 1 |
| Evans, CJ | 1 |
| Murphy, K | 1 |
| Hall, JE | 1 |
| Bailey, DM | 1 |
| Mitsis, G | 1 |
| Edden, RA | 1 |
| Wise, RG | 1 |
| Timofeev, I | 1 |
| Nortje, J | 1 |
| Al-Rawi, PG | 1 |
| Hutchinson, PJ | 1 |
| Gupta, AK | 1 |
| Blood, AB | 1 |
| Hunter, CJ | 1 |
| Power, GG | 1 |
| Hirai, K | 2 |
| Sugawara, T | 1 |
| Chan, PH | 1 |
| Basus, VJ | 2 |
| James, TL | 2 |
| Litt, L | 2 |
| Cappellini, M | 1 |
| Rapisardi, G | 1 |
| Cioni, ML | 1 |
| Fonda, C | 1 |
| Peebles, DM | 1 |
| Dixon, JC | 1 |
| Thornton, JS | 1 |
| Cady, EB | 3 |
| Priest, A | 1 |
| Miller, SL | 1 |
| Blanco, CE | 1 |
| Mulder, TL | 1 |
| Ordidge, RJ | 1 |
| Rodeck, CH | 1 |
| Mourek, J | 1 |
| Smídová, L | 1 |
| Slapetová, V | 1 |
| Koudelová, J | 1 |
| CAIN, SM | 1 |
| SCHEINBERG, P | 1 |
| BOURNE, B | 1 |
| REINMUTH, OM | 1 |
| Glenn, TC | 1 |
| Kelly, DF | 1 |
| Boscardin, WJ | 1 |
| McArthur, DL | 1 |
| Vespa, P | 1 |
| Oertel, M | 1 |
| Hovda, DA | 1 |
| Bergsneider, M | 1 |
| Hillered, L | 2 |
| Martin, NA | 1 |
| Sarrafzadeh, AS | 1 |
| Kiening, KL | 1 |
| Callsen, TA | 1 |
| Unterberg, AW | 1 |
| Bauer, R | 1 |
| Gabl, M | 1 |
| Obwegeser, A | 1 |
| Galiano, K | 1 |
| Barbach, J | 1 |
| Mohsenipour, I | 1 |
| Khong, PL | 1 |
| Tse, C | 1 |
| Wong, IY | 1 |
| Lam, BC | 1 |
| Cheung, PT | 1 |
| Goh, WH | 1 |
| Kwong, NS | 1 |
| Ooi, GC | 1 |
| Allen, NJ | 1 |
| Káradóttir, R | 1 |
| Attwell, D | 1 |
| Liu, HC | 1 |
| Zhang, H | 1 |
| Li, ZP | 1 |
| Wang, B | 1 |
| Zhu, L | 1 |
| Shi, ZY | 1 |
| Wu, XM | 1 |
| Zhang, ZJ | 1 |
| Jin, SY | 1 |
| Puchowicz, MA | 1 |
| Emancipator, DS | 1 |
| Xu, K | 1 |
| Magness, DL | 1 |
| Ndubuizu, OI | 1 |
| Lust, WD | 1 |
| LaManna, JC | 1 |
| Zoremba, N | 1 |
| Homola, A | 1 |
| Rossaint, R | 1 |
| Syková, E | 1 |
| Moxon-Lester, L | 1 |
| Sinclair, K | 1 |
| Burke, C | 1 |
| Cowin, GJ | 1 |
| Rose, SE | 1 |
| Colditz, P | 1 |
| Geeraerts, T | 1 |
| Friggeri, A | 1 |
| Mazoit, JX | 1 |
| Benhamou, D | 1 |
| Duranteau, J | 1 |
| Vigué, B | 1 |
| Moritz, S | 1 |
| Kasprzak, P | 1 |
| Woertgen, C | 1 |
| Taeger, K | 1 |
| Metz, C | 1 |
| Siesjö, BK | 3 |
| Nattie, EE | 1 |
| Edwards, WH | 1 |
| Marin-Padilla, M | 1 |
| Hoyer, S | 1 |
| Prien, T | 1 |
| Lawin, P | 1 |
| Schoeppner, H | 1 |
| Altman, DI | 1 |
| Young, RS | 1 |
| Yagel, SK | 1 |
| Welsh, FA | 1 |
| Sims, RE | 1 |
| McKee, AE | 1 |
| Winn, HR | 1 |
| Rubio, R | 1 |
| Berne, RM | 1 |
| Gardiner, M | 1 |
| Smith, ML | 1 |
| Kågström, E | 1 |
| Shohami, E | 1 |
| MacMillan, V | 1 |
| Takata, T | 1 |
| Okada, Y | 1 |
| Bachelard, H | 1 |
| Badar-Goffer, R | 1 |
| Ben-Yoseph, O | 2 |
| Morris, P | 1 |
| Thatcher, N | 1 |
| Tanaka, H | 1 |
| Kazui, T | 1 |
| Sato, H | 1 |
| Inoue, N | 1 |
| Yamada, O | 1 |
| Komatsu, S | 1 |
| Landolt, H | 1 |
| Langemann, H | 1 |
| Mendelowitsch, A | 1 |
| Gratzl, O | 1 |
| Badar-Goffer, RS | 1 |
| Morris, PG | 1 |
| Bachelard, HS | 3 |
| Thoresen, M | 1 |
| Bågenholm, R | 1 |
| Løberg, EM | 1 |
| Apriccna, F | 1 |
| Vannucci, RC | 3 |
| Brucklacher, RM | 1 |
| Vannucci, SJ | 2 |
| Penrice, J | 2 |
| Lorek, A | 1 |
| Wylezinska, M | 1 |
| Amess, PN | 1 |
| Aldridge, RF | 1 |
| Stewart, A | 1 |
| Wyatt, JS | 1 |
| Reynolds, EO | 2 |
| Gleitz, J | 1 |
| Tosch, C | 1 |
| Peters, T | 1 |
| Pérez-Pinzón, MA | 1 |
| Lutz, PL | 1 |
| Sick, TJ | 1 |
| Rosenthal, M | 1 |
| LeBlanc, MH | 1 |
| Qian, XB | 1 |
| Cai, ZW | 1 |
| Lowry, JP | 1 |
| Demestre, M | 1 |
| Fillenz, M | 1 |
| Valadka, AB | 1 |
| Goodman, JC | 2 |
| Gopinath, SP | 2 |
| Uzura, M | 1 |
| Robertson, CS | 2 |
| Valtysson, J | 1 |
| Persson, L | 1 |
| Nakai, T | 1 |
| Rhine, WD | 1 |
| Okada, T | 1 |
| Stevenson, DK | 1 |
| Spielman, DM | 1 |
| Malisza, KL | 1 |
| Kozlowski, P | 1 |
| Ning, G | 1 |
| Bascaramurty, S | 1 |
| Tuor, UI | 1 |
| Mehmet, H | 1 |
| Yue, X | 1 |
| Cady, E | 1 |
| Wyatt, JC | 1 |
| Sarraf, C | 1 |
| Squier, M | 1 |
| Edwards, AD | 1 |
| Groenendaal, F | 1 |
| de Graaf, RA | 1 |
| van Vliet, G | 1 |
| Nicolay, K | 1 |
| Huang, CC | 1 |
| Wang, ST | 1 |
| Chang, YC | 1 |
| Lin, KP | 1 |
| Wu, PL | 1 |
| Perlman, JM | 1 |
| Hedley-Whyte, ET | 1 |
| Fandino, J | 1 |
| Stocker, R | 1 |
| Prokop, S | 1 |
| Trentz, O | 1 |
| Imhof, HG | 1 |
| Ip-Yam, PC | 1 |
| Thomas, SD | 1 |
| Jackson, M | 1 |
| Rashid, A | 1 |
| Behl, S | 1 |
| Murata, T | 1 |
| Omata, N | 1 |
| Fujibayashi, Y | 1 |
| Waki, A | 1 |
| Sadato, N | 1 |
| Yoshimoto, M | 1 |
| Wada, Y | 1 |
| Yonekura, Y | 1 |
| Yamagata, K | 1 |
| Tagami, M | 1 |
| Ikeda, K | 1 |
| Noguchi, T | 1 |
| Yamori, Y | 1 |
| Nara, Y | 1 |
| Chih, CP | 1 |
| He, J | 1 |
| Sly, TS | 1 |
| Roberts, EL | 1 |
| Bell, MJ | 1 |
| Kochanek, PM | 1 |
| Carcillo, JA | 1 |
| Clark, RS | 1 |
| Marion, DW | 1 |
| Mi, Z | 1 |
| Jackson, EK | 1 |
| Lee, EJ | 1 |
| Hung, YC | 1 |
| Conte, A | 1 |
| Suzuki, M | 2 |
| Sato, K | 1 |
| Dohi, S | 1 |
| Sato, T | 1 |
| Matsuura, A | 1 |
| Hiraide, A | 1 |
| Cui, XY | 1 |
| Li, L | 1 |
| An, YY | 1 |
| Lu, GW | 1 |
| Mujsce, DJ | 1 |
| Bômont, L | 1 |
| Bilger, A | 1 |
| Boyet, S | 1 |
| Vert, P | 1 |
| Nehlig, A | 1 |
| Kauppinen, RA | 1 |
| Williams, SR | 1 |
| Seo, K | 1 |
| Ishimaru, S | 1 |
| Hossmann, KA | 1 |
| Nishizawa, K | 1 |
| Tanaka, K | 1 |
| Shimada, M | 1 |
| Ohno, M | 1 |
| Obrenovitch, TP | 1 |
| Hartell, N | 1 |
| Barratt, S | 1 |
| Symon, L | 1 |
| Palmer, GC | 1 |
| Garofalo, O | 1 |
| Cox, DW | 1 |
| Hope, PL | 1 |
| Chu, A | 1 |
| Delpy, DT | 1 |
| Gardiner, RM | 1 |
| Vasta, F | 1 |
| Petroni, A | 1 |
| Borghi, A | 1 |
| Blasevich, M | 1 |
| Grossi, P | 1 |
| Bertazzo, A | 1 |
| Galli, C | 1 |
| Dauberschmidt, R | 1 |
| Bender, V | 1 |
| Klages, G | 1 |
| Kynast, J | 1 |
| Förster, I | 1 |
| Dressler, C | 1 |
| Meyer, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain During Effort : Effects of Hypoxia With Respiratory Patients[NCT02854280] | 33 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| Ketone Esters for Optimization of Cognitive Performance in Hypoxia[NCT03659825] | 16 participants (Anticipated) | Interventional | 2018-09-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for lactic acid and Anoxia, Brain
| Article | Year |
|---|---|
Flat spin and negative Gz in high-altitude free fall: pathophysiology, prevention, and treatment.
Topics: Altitude; Arrhythmias, Cardiac; Blood Glucose; Brain Edema; Cerebrovascular Circulation; Confusion; | 2013 |
A systematic review of Magnetic Resonance Imaging and Spectroscopy in brain injury after drowning.
Topics: Aspartic Acid; Brain Injuries; Child; Child, Preschool; Drowning; Female; Humans; Hypoxia, Brain; In | 2009 |
[Magnetic resonance spectroscopy for cerebral imaging].
Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea | 2010 |
Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance.
Topics: Acidosis; Animals; Blood Glucose; Brain; Brain Ischemia; Carbon Dioxide; Glucose; Hypoxia, Brain; In | 1982 |
Cell damage in the brain: a speculative synthesis.
Topics: Acidosis; Animals; Biological Transport, Active; Brain Ischemia; Calcium; Cell Membrane; Cerebrovasc | 1981 |
Effect of glucose on perinatal hypoxic-ischemic brain damage.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Brain Ischemia; Glucose; Humans; Hyp | 1992 |
Cyclic nucleotides in stroke and related cerebrovascular disorders.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adenylyl Cyclas | 1985 |
3 trials available for lactic acid and Anoxia, Brain
| Article | Year |
|---|---|
Higher physiological vulnerability to hypoxic exposure with advancing age in the human brain.
Topics: Adolescent; Adult; Aging; Cerebrovascular Circulation; Female; Humans; Hypoxia, Brain; Lactic Acid; | 2020 |
Extracellular brain pH with or without hypoxia is a marker of profound metabolic derangement and increased mortality after traumatic brain injury.
Topics: Adult; Biomarkers; Brain; Brain Injuries; Disease-Free Survival; Female; Glucose; Humans; Hydrogen-I | 2013 |
Effects of temperature strategy during cardiopulmonary bypass on cerebral oxygen balance.
Topics: Aged; Body Temperature Regulation; Brain; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary D | 2000 |
86 other studies available for lactic acid and Anoxia, Brain
| Article | Year |
|---|---|
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Drug Administration Schedule; Dr | 2020 |
Hippocampal and cerebellar histological changes and their behavioural repercussions caused by brain ischaemic hypoxia experimentally induced by sodium nitrite.
Topics: Animals; Anxiety; Blood Glucose; Brain Ischemia; Cerebellum; Cholesterol; Depression; Hippocampus; H | 2017 |
Protocolized Brain Oxygen Optimization in Subarachnoid Hemorrhage.
Topics: Aged; Brain; Carbon Dioxide; Cerebrovascular Circulation; Clinical Protocols; Cohort Studies; Female | 2019 |
Cerebral extracellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury.
Topics: Adult; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Cohort Studies; Extracellular S | 2013 |
The role of glycogen, glucose and lactate in neuronal activity during hypoxia in the hooded seal (Cystophora cristata) brain.
Topics: Adaptation, Physiological; Animals; Brain; Cell Hypoxia; Electrophysiology; Glucose; Glycogen; Hypox | 2014 |
Predictors of neurological outcomes after successful extracorporeal cardiopulmonary resuscitation.
Topics: Aged; Brain; Brain Death; Cardiopulmonary Resuscitation; Extracorporeal Membrane Oxygenation; Female | 2015 |
A probable dual mode of action for both L- and D-lactate neuroprotection in cerebral ischemia.
Topics: Animals; Behavior, Animal; Brain Chemistry; Brain Ischemia; Carrier Proteins; Cell Death; Glucose; H | 2015 |
[A role of stress-induced neuroendocrine disorders and tissue hypoxia in the thanatogenesis of traumatic intracranial hematomas].
Topics: Adrenocorticotropic Hormone; Adult; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; | 2015 |
Hemichannel-mediated release of lactate.
Topics: Animals; Biosensing Techniques; Brain; Connexins; Electrophysiological Phenomena; Hypoxia, Brain; In | 2016 |
Assessment of phospholipid synthesis related biomarkers for perinatal asphyxia: a piglet study.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Biomarkers; Choline; Female; Humans; Hypoxia-Ischemi | 2017 |
Non-invasive detection and quantification of human foetal brain lactate in utero by magnetic resonance spectroscopy.
Topics: Adult; Biomarkers; Brain; Brain Chemistry; Female; Fetal Growth Retardation; Fetal Hypoxia; Fetus; H | 2010 |
Reduced muscle activation during exercise related to brain oxygenation and metabolism in humans.
Topics: Adult; Algorithms; Blood Glucose; Brain Chemistry; Carbon Dioxide; Elbow; Exercise; Hemodynamics; He | 2010 |
N-acetylcysteine improves hemodynamics and reduces oxidative stress in the brains of newborn piglets with hypoxia-reoxygenation injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blood Pressure; Caspase 3; Cerebral Cortex; Cerebro | 2010 |
[Is lactate a good indicator of brain tissue hypoxia in the acute phase of traumatic brain injury? Results of a pilot study in 21 patients].
Topics: Adult; Biomarkers; Brain Injuries; Diagnosis, Differential; Energy Metabolism; Glucose; Humans; Hypo | 2010 |
Post-traumatic hypoxia exacerbates brain tissue damage: analysis of axonal injury and glial responses.
Topics: Amyloid beta-Protein Precursor; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bl | 2010 |
[Cerebral hypoxia or cyanide intoxication?].
Topics: Adult; Air Pollutants, Occupational; Asphyxia; Diagnosis, Differential; Female; Humans; Hydrogen Cya | 2010 |
Nanoerythropoietin is 10-times more effective than regular erythropoietin in neuroprotection in a neonatal rat model of hypoxia and ischemia.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Erythropoietin; Ex | 2012 |
Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxia.
Topics: Acute Disease; Adult; Brain; Female; Humans; Hypoxia; Hypoxia, Brain; Lactates; Lactic Acid; Magneti | 2013 |
The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Fema | 2002 |
Cytochrome c associated apoptosis during ATP recovery after hypoxia in neonatal rat cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Caspase 9; Caspases | 2002 |
Temperature control of respiring rat brain slices during high field NMR spectroscopy.
Topics: Animals; Brain Chemistry; Deuterium Oxide; Hypoxia, Brain; In Vitro Techniques; Lactic Acid; Magneti | 2003 |
Acute hypoxic encephalopathy in the full-term newborn: correlation between Magnetic Resonance Spectroscopy and neurological evaluation at short and long term.
Topics: Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatinine; Humans; Hypoxia, Brain; Infa | 2002 |
Magnetic resonance proton spectroscopy and diffusion weighted imaging of chick embryo brain in ovo.
Topics: Adaptation, Physiological; Alanine; Animals; Body Water; Brain; Chick Embryo; Creatine; Diffusion Ma | 2003 |
[A possible protective effect of hypothermia on the posthypoxic state of the cerebral cortex in the early stages of development].
Topics: Animals; Animals, Newborn; Cerebral Cortex; Cold Temperature; Hydrogen-Ion Concentration; Hypothermi | 2003 |
Cerebral excess lactate production during hyperventilation of anesthetized dogs.
Topics: Animals; Cell Respiration; Dogs; Humans; Hyperventilation; Hypoxia, Brain; Lactates; Lactic Acid; Re | 1962 |
HUMAN CEREBRAL LACTATE AND PYRUVATE EXTRACTION. I. CONTROL SUBJECTS.
Topics: Blood Chemical Analysis; Brain; Brain Chemistry; Carbohydrate Metabolism; Cerebral Arteries; Cranial | 1965 |
Energy dysfunction as a predictor of outcome after moderate or severe head injury: indices of oxygen, glucose, and lactate metabolism.
Topics: Adult; Brain; Brain Injuries; Cerebrovascular Circulation; Cohort Studies; Energy Metabolism; Female | 2003 |
Metabolic changes during impending and manifest cerebral hypoxia in traumatic brain injury.
Topics: Adolescent; Adult; Aged; Brain; Brain Injuries; Female; Glutamic Acid; Humans; Hypoxia, Brain; Lacti | 2003 |
Neurochemical monitoring using intracerebral microdialysis during cardiac resuscitation.
Topics: Adult; Biomarkers; Brain Chemistry; Cause of Death; Cerebral Infarction; Energy Metabolism; Fatal Ou | 2004 |
Diffusion-weighted imaging and proton magnetic resonance spectroscopy in perinatal hypoxic-ischemic encephalopathy: association with neuromotor outcome at 18 months of age.
Topics: Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Brain; Choline; Creatine; Diffusion Magnetic Reso | 2004 |
A preferential role for glycolysis in preventing the anoxic depolarization of rat hippocampal area CA1 pyramidal cells.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Cyanides; Energy Metabolism; Glucose; Glutamic Acid; G | 2005 |
[Effect of high-oxygen water on enhancing anoxia endurance and anti-fatigue function and the possible mechanism].
Topics: Animals; Fatigue; Hypoxia; Hypoxia, Brain; Lactic Acid; Male; Mice; Muscle, Skeletal; Oxygen; Oxygen | 2005 |
[Prevention of Rhodiola-astragalus membranaceus compounds against simulated plateau hypoxia brain injury in rat].
Topics: Adenosine Triphosphatases; Altitude; Animals; Astragalus propinquus; Atmosphere Exposure Chambers; C | 2005 |
Adaptation to chronic hypoxia during diet-induced ketosis.
Topics: Adaptation, Physiological; Animals; Chronic Disease; Diet; Glucose; Glycolysis; Hypoxia, Brain; Keto | 2005 |
Brain metabolism and extracellular space diffusion parameters during and after transient global hypoxia in the rat cortex.
Topics: Animals; Cerebral Cortex; Diffusion; Disease Models, Animal; Down-Regulation; Energy Metabolism; Ext | 2007 |
Increased cerebral lactate during hypoxia may be neuroprotective in newborn piglets with intrauterine growth restriction.
Topics: Animals; Animals, Newborn; Apoptosis; Birth Weight; Brain; Brain Chemistry; Cell Count; Diffusion Ma | 2007 |
Posttraumatic brain vulnerability to hypoxia-hypotension: the importance of the delay between brain trauma and secondary insult.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Gl | 2008 |
The accuracy of jugular bulb venous monitoring in detecting cerebral ischemia in awake patients undergoing carotid endarterectomy.
Topics: Aged; Aged, 80 and over; Anesthesia, Conduction; Brain Ischemia; Data Interpretation, Statistical; E | 2008 |
Newborn puppy cerebral acid-base regulation in experimental asphyxia and recovery.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Animals; Animals, Newborn; Bicarbonates; Blood-Brain B | 1984 |
The effect of naftidrofuryl on cyanide-induced hypoxic damage to glucose and energy metabolism in brain cortex of rats.
Topics: Animals; Body Temperature; Carbon Dioxide; Cerebral Cortex; Cyanides; Energy Metabolism; Furans; Glu | 1984 |
[Brain function and artificial respiration].
Topics: Acid-Base Equilibrium; Brain Ischemia; Carbon Dioxide; Cerebrovascular Circulation; Electroencephalo | 1984 |
Effects of dexamethasone in hypoxic-ischemic brain injury in the neonatal rat.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain; Brain Edema; Brain Ischemia; Dexamethasone; Dose-Re | 1984 |
Effect of glucose on recovery of energy metabolism following hypoxia-oligemia in mouse brain: dose-dependence and carbohydrate specificity.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Brain; Carbohydrates; Dose-Response Relationship, Dr | 1983 |
Brain adenosine concentration during hypoxia in rats.
Topics: Acute Disease; Adenine Nucleotides; Adenosine; Animals; Arteries; Blood; Brain Chemistry; Carbon Dio | 1981 |
Influence of blood glucose concentration on brain lactate accumulation during severe hypoxia and subsequent recovery of brain energy metabolism.
Topics: Animals; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Hypoxia, Brain; Lacta | 1982 |
The effects of imidazole-4-acetic acid upon the energy metabolism of normoxic and hypoxic rat brain.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Animals; Blood | 1982 |
Effects of deprivation of oxygen or glucose on the neural activity in the guinea pig hippocampal slice--intracellular recording study of pyramidal neurons.
Topics: Adenosine Triphosphate; Animals; Calcium; Energy Metabolism; Glucose; Guinea Pigs; Hippocampus; Hypo | 1995 |
Studies on metabolic regulation using NMR spectroscopy.
Topics: Animals; Brain; Calcium; Energy Metabolism; Glucose; Glutamic Acid; Glycerophosphates; Guinea Pigs; | 1993 |
Experimental study on the optimum flow rate and pressure for selective cerebral perfusion.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain Ischemia; Cardiopulmonary Bypass; Carotid Arteri | 1995 |
Neurochemical monitoring and on-line pH measurements using brain microdialysis in patients in intensive care.
Topics: Acid-Base Equilibrium; Adult; Ascorbic Acid; Blood Glucose; Blood-Brain Barrier; Brain Edema; Brain | 1994 |
Glycerol 3-phosphate and lactate as indicators of the cerebral cytoplasmic redox state in severe and mild hypoxia respectively: a 13C- and 31P-n.m.r. study.
Topics: Acetates; Adenosine Triphosphate; Alanine; Cerebral Cortex; Cytoplasm; gamma-Aminobutyric Acid; Gas | 1993 |
The stress of being restrained reduces brain damage after a hypoxic-ischaemic insult in the 7-day-old rat.
Topics: Animals; Animals, Newborn; Blood Chemical Analysis; Blood Glucose; Body Temperature; Brain; Brain Is | 1996 |
The effect of hyperglycemia on cerebral metabolism during hypoxia-ischemia in the immature rat.
Topics: Adenosine Triphosphate; Animals; Body Water; Brain; Brain Ischemia; Carotid Arteries; Glucose; Glyco | 1996 |
Proton magnetic resonance spectroscopy of the brain in normal preterm and term infants, and early changes after perinatal hypoxia-ischemia.
Topics: Asphyxia Neonatorum; Brain; Brain Ischemia; Case-Control Studies; Humans; Hypoxia, Brain; Infant, Ne | 1996 |
Continuous enzyme-linked fluorometric detection of L-(+)-lactate released from rat brain vesicles under anoxic conditions.
Topics: Animals; Brain Chemistry; Calcium; Enzyme-Linked Immunosorbent Assay; Fura-2; Hypoxia, Brain; In Vit | 1996 |
Metabolic mechanisms of anoxia tolerance in the turtle brain.
Topics: Adenosine Triphosphate; Anaerobiosis; Animals; Body Temperature Regulation; Cerebellum; Female; Glyc | 1997 |
The effect of glucose during ischemia on brain ATP, lactate, and glutamate in piglets.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Body Temperature; Brain; Brain Chemistry; Brain I | 1997 |
Relation between cerebral blood flow and extracellular glucose in rat striatum during mild hypoxia and hyperoxia.
Topics: Anesthesia, General; Animals; Cerebrovascular Circulation; Chloral Hydrate; Corpus Striatum; Energy | 1998 |
Comparison of brain tissue oxygen tension to microdialysis-based measures of cerebral ischemia in fatally head-injured humans.
Topics: Adult; Brain; Brain Death; Brain Injuries; Cations; Chromatography, High Pressure Liquid; Excitatory | 1998 |
Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brain.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Electroencephalography; Energy Metabolism; Extracellular S | 1998 |
Strategy for lipid suppression in lactate imaging using STIR-DQCT: a study of hypoxic-ischemic brain injury.
Topics: Animals; Brain; Brain Ischemia; Hypoxia, Brain; Image Enhancement; Lactic Acid; Magnetic Resonance S | 1998 |
Metabolite changes in neonatal rat brain during and after cerebral hypoxia-ischemia: a magnetic resonance spectroscopic imaging study.
Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Female; | 1999 |
Relation of impaired energy metabolism to apoptosis and necrosis following transient cerebral hypoxia-ischaemia.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Brain Ischemia; Cell Count; Energy Metabolism; Gyrus Ci | 1998 |
Effects of hypoxia-ischemia and inhibition of nitric oxide synthase on cerebral energy metabolism in newborn piglets.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Anima | 1999 |
Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy.
Topics: Asphyxia Neonatorum; Biomarkers; Brain Ischemia; Creatinine; Developmental Disabilities; Fetal Hypox | 1999 |
Markers of asphyxia and neonatal brain injury.
Topics: Asphyxia Neonatorum; Biomarkers; Brain Ischemia; Creatinine; Fetal Hypoxia; Humans; Hypoxia, Brain; | 1999 |
Leukoencephalopathy and raised brain lactate from heroin vapor inhalation.
Topics: Administration, Inhalation; Brain; Demyelinating Diseases; Heroin; Heroin Dependence; Humans; Hypoxi | 2000 |
Cerebral oxygenation and systemic trauma related factors determining neurological outcome after brain injury.
Topics: Adolescent; Adult; APACHE; Brain Injuries; Catheterization, Peripheral; Female; Glasgow Coma Scale; | 2000 |
Posthypoxic reoxygenation-induced neurotoxicity prevented by free radical scavenger and NMDA/non-NMDA antagonist in tandem as revealed by dynamic changes in glucose metabolism with positron autoradiography.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Autoradiography; Cell Hypoxia; Cell Survival; Colorin | 2000 |
Reduced production of lactate during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Astrocytes; Carrier Proteins; Cell Death; Cells, Cultured; Fetus; Hypoxia, Brain; L-Lactate | 2000 |
Comparison of glucose and lactate as substrates during NMDA-induced activation of hippocampal slices.
Topics: Animals; Biological Transport; Cell Hypoxia; Coumaric Acids; Dose-Response Relationship, Drug; Energ | 2001 |
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.
Topics: Adenosine; Adolescent; Adult; Blood Gas Analysis; Blood Glucose; Brain Chemistry; Brain Injuries; Ce | 2001 |
Marked anemic hypoxia deteriorates cerebral hemodynamics and brain metabolism during massive intracerebral hemorrhage.
Topics: Anemia; Animals; Blood Pressure; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Mo | 2001 |
Role of pH on the calcium ion dependence of the nitric oxide synthase in the carp brain.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Brain; Calcium; Carps; Cerebrovascular Circulation | 2001 |
Effect of beta-hydroxybutyrate, a cerebral function improving agent, on cerebral hypoxia, anoxia and ischemia in mice and rats.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Blood Pressure; Body Water; Brain; Brain Ede | 2001 |
Changes in the contents of glycogen and lactate in the brain and blood during hypoxic preconditioning.
Topics: Animals; Brain; Diencephalon; Female; Glycogen; Hypoxia, Brain; Ischemic Preconditioning; Lactic Aci | 2001 |
Acute hypoxia induces specific changes in local cerebral glucose utilization at different postnatal ages in the rat.
Topics: Acute Disease; Animals; Brain; Data Interpretation, Statistical; Glucose; Hypoxia, Brain; Lactates; | 1992 |
Nondestructive detection of glutamate by 1H nuclear magnetic resonance spectroscopy in cortical brain slices from the guinea pig: evidence for changes in detectability during severe anoxic insults.
Topics: Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Creatinine; Energy Metabolism; | 1991 |
Two-stage resuscitation of the cat brain after prolonged cardiac arrest.
Topics: Adenosine Triphosphate; Animals; Brain Chemistry; Cardiopulmonary Resuscitation; Cats; Cerebrovascul | 1991 |
[Experimental study on pathogenesis of neonatal hypoxic-ischemic encephalopathy. II. Energy metabolism in the brain].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Brain Ischemia; Cer | 1990 |
Simultaneous recording of tissue PCO2, interstitial pH and potassium activity in the rat cerebral cortex during anoxia and the subsequent recovery period.
Topics: Animals; Carbon Dioxide; Cerebral Cortex; Hydrogen-Ion Concentration; Hypercapnia; Hypoxia, Brain; L | 1989 |
Brain levels of NADH and NAD+ under hypoxic and hypoglycaemic conditions in vitro.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Glucose; Guinea Pigs; Hypoglycemia; Hypoxia, Brain; | 1988 |
Brain metabolism and intracellular pH during ischaemia and hypoxia: an in vivo 31P and 1H nuclear magnetic resonance study in the lamb.
Topics: Animals; Brain; Brain Chemistry; Brain Ischemia; Hydrogen-Ion Concentration; Hypoxia, Brain; Lactate | 1987 |
Cerebral metabolic responses of hyperglycemic immature rats to hypoxia-ischemia.
Topics: Adenine Nucleotides; Animals; Animals, Newborn; Blood Glucose; Brain; Brain Ischemia; Glucose; Hyper | 1987 |
Effects of hypoxia and recovery on brain eicosanoids and carbohydrate metabolites in rat brain cortex.
Topics: Animals; Blood Glucose; Cerebral Cortex; Fatty Acids; Glucose; Glycogen; Hypoxia, Brain; Lactates; L | 1987 |
[Lactate concentration in the ventricular fluid and blood plasma following severe craniocerebral trauma].
Topics: Adult; Brain Injuries; Brain Ischemia; Coma; Female; Humans; Hypoxia, Brain; Intracranial Pressure; | 1985 |