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lactic acid and Anesthesia Related Hyperthermia

lactic acid has been researched along with Anesthesia Related Hyperthermia in 20 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Clinical characteristics of malignant hyperthermia (MH) in pediatric patients have not been elucidated."1.40Malignant hyperthermia in children: an analysis of the North American malignant hyperthermia registry. ( Litman, RS; Nelson, P, 2014)
"Halothane was discontinued after the administration of 0."1.37Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs. ( Becker, S; Burmester, S; Gerbershagen, MU; Kröner, L; Lenz, D; Schütte, JK; Starosse, A; Wappler, F, 2011)
" Reproducible shifts in the dose-response of skeletal muscle to caffeine and halothane are the basis of the current in vitro diagnostic caffeine-halothane contracture test."1.33Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis. ( Bina, S; Bünger, R; Cowan, G; Karaian, J; Mongan, P; Muldoon, S, 2006)
" MH susceptibility leads to a leftward shift of the dose-response curve for IM lactate after local injection of halothane and caffeine."1.33The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs. ( Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F, 2006)
"In the muscles of pigs with malignant hyperthermia syndrome the process of glycolysis is accelerated by the pre-slaughter stress."1.28[Postmortem metabolism of glycogen in the muscles of healthy pigs and in pigs with the malignant hyperthermia syndrome]. ( Uhrín, P, 1990)
"The effects of an induced malignant hyperthermia (MH) crisis have been studied in the intact pig."1.27In vivo induced malignant hyperthermia in pigs. I. Physiological and biochemical changes and the influence of dantrolene sodium. ( Crul, JF; de Bruyn, CH; Gielen, MJ; Oerlemans, FT; van Bennekom, CA; Verburg, MP, 1984)
"Catecholamine levels were higher in malignant hyperthermia-sensitive than in normal pigs at all sampling times."1.27Electrical stimulation triggers porcine malignant hyperthermia. ( Ahern, CP; Gronert, GA; Milde, JH, 1985)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's3 (15.00)18.2507
2000's5 (25.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
House, CM1
Tipton, MJ1
Hopkins, PM1
Roiz de Sa, D1
Nelson, P1
Litman, RS1
Schuster, F4
Hager, M3
Metterlein, T3
Muellenbach, RM1
Wurmb, T1
Wunder, C1
Roewer, N4
Anetseder, M3
Kranke, P1
Schütte, JK1
Becker, S1
Burmester, S1
Starosse, A1
Lenz, D1
Kröner, L1
Wappler, F2
Gerbershagen, MU2
Johannsen, S1
Berberich, C1
Roth, C1
Reiners, K1
Fiege, M1
Weisshorn, R1
Kolodzie, K1
Schulte Am Esch, J1
Bina, S1
Cowan, G1
Karaian, J1
Muldoon, S1
Mongan, P1
Bünger, R1
Schöll, H1
Müller, R1
Verburg, MP1
Oerlemans, FT1
van Bennekom, CA1
Gielen, MJ1
de Bruyn, CH1
Crul, JF1
Nelson, TE1
Flewellen, EH1
Gloyna, DF1
Hill, BD1
McManus, AC1
Brown, NN1
Playford, CL1
Noble, JW1
Wedel, DJ1
Iaizzo, PA1
Milde, JH4
O'Brien, PJ1
Shen, H1
Weiler, J1
Ianuzzo, CD1
Wittnich, C1
Moe, GW1
Armstrong, PW1
Uhrín, P1
Ording, H2
Fonsmark, L1
Gronert, GA3
Ahern, CP3
White, RD1
Nielsen, VG1

Trials

1 trial available for lactic acid and Anesthesia Related Hyperthermia

ArticleYear
A bovine stress syndrome associated with exercise-induced hyperthermia.
    Australian veterinary journal, 2000, Volume: 78, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Bicarbonates; Blood Glucose; Body Temperature; Cattle; Cattle

2000

Other Studies

19 other studies available for lactic acid and Anesthesia Related Hyperthermia

ArticleYear
Thermoregulation and markers of muscle breakdown in malignant hyperthermia susceptible volunteers during an acute heat tolerance test.
    Journal of science and medicine in sport, 2019, Volume: 22, Issue:5

    Topics: Adult; Biomarkers; Body Temperature; Body Temperature Regulation; Creatine Kinase; Exercise Test; Ho

2019
Malignant hyperthermia in children: an analysis of the North American malignant hyperthermia registry.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:2

    Topics: Adolescent; Age Factors; Anesthesia; Body Temperature; Child; Child, Preschool; Creatine Kinase; Fem

2014
[In-vivo diagnosis of malignant hyperthermia susceptibility: a microdialysis study].
    Der Anaesthesist, 2008, Volume: 57, Issue:8

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; D

2008
Magnesium does not influence the clinical course of succinylcholine-induced malignant hyperthermia.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:5

    Topics: Animals; Biomarkers; Carbon Dioxide; Disease Models, Animal; Energy Metabolism; Hemodynamics; Hydrog

2011
Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:4

    Topics: Animals; Biomarkers; Chemistry, Pharmaceutical; Dantrolene; Disease Models, Animal; Halothane; Hemod

2011
Screening test for malignant hyperthermia in patients with persistent hyperCKemia: a pilot study.
    Muscle & nerve, 2013, Volume: 47, Issue:5

    Topics: Adult; Creatine Kinase; Disease Susceptibility; Female; Humans; Lactic Acid; Male; Malignant Hyperth

2013
In vitro and in vivo effects of the phosphodiesterase-III inhibitor enoximone on malignant hyperthermia-susceptible swine.
    Anesthesiology, 2003, Volume: 98, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Body Temperature; Carbon Dioxide; Cyclic Nucleotide Ph

2003
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    Anesthesiology, 2006, Volume: 104, Issue:1

    Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; A

2006
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Re

2006
In vivo induced malignant hyperthermia in pigs. I. Physiological and biochemical changes and the influence of dantrolene sodium.
    Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Adenylate Kinase; Animals; Creatine; Dantrolene; Inosine Monophos

1984
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:6

    Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques;

1983
Desflurane is a trigger of malignant hyperthermia in susceptible swine.
    Anesthesiology, 1991, Volume: 74, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Blood; Body Temperature; Carbon Dioxide; Desflurane; Disease Suscep

1991
Cardiac and muscle fatigue due to relative functional overload induced by excessive stimulation, hypersensitive excitation-contraction coupling, or diminished performance capacity correlates with sarcoplasmic reticulum failure.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:2

    Topics: Animals; Calcium; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Echocardiography; Electric Sti

1991
[Postmortem metabolism of glycogen in the muscles of healthy pigs and in pigs with the malignant hyperthermia syndrome].
    Veterinarni medicina, 1990, Volume: 35, Issue:7

    Topics: Animals; Glycogen; Lactates; Lactic Acid; Malignant Hyperthermia; Muscles; Postmortem Changes; Swine

1990
Use of vecuronium and doxapram in patients susceptible to malignant hyperthermia.
    British journal of anaesthesia, 1988, Volume: 60, Issue:4

    Topics: Adult; Anesthesia, General; Body Temperature; Carbon Dioxide; Disease Susceptibility; Doxapram; Huma

1988
Effect of CO2, calcium, digoxin, and potassium on cardiac and skeletal muscle metabolism in malignant hyperthermia susceptible swine.
    Anesthesiology, 1986, Volume: 64, Issue:1

    Topics: Animals; Calcium; Carbon Dioxide; Digoxin; Lactates; Lactic Acid; Malignant Hyperthermia; Muscles; M

1986
Atracurium and its antagonism by neostigmine (plus glycopyrrolate) in patients susceptible to malignant hyperthermia.
    British journal of anaesthesia, 1986, Volume: 58, Issue:9

    Topics: Adult; Atracurium; Body Temperature; Carbon Dioxide; Disease Susceptibility; Glycopyrrolate; Humans;

1986
Treatment of porcine malignant hyperthermia: lactate gradient from muscle to blood.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:6

    Topics: Animals; Bicarbonates; Carbon Dioxide; Dantrolene; Halothane; Lactates; Lactic Acid; Malignant Hyper

1986
Electrical stimulation triggers porcine malignant hyperthermia.
    Research in veterinary science, 1985, Volume: 39, Issue:2

    Topics: Animals; Catecholamines; Electric Stimulation; Lactates; Lactic Acid; Malignant Hyperthermia; Swine

1985