lactic acid has been researched along with Anaplastic Astrocytoma in 21 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The choline/NAA ratio was 3." | 2.40 | Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas. ( Ball, WS; Ballard, E; Dunn, RS; Egnaczyk, GF; Holland, SK; Hwang, JH, 1998) |
| "Proton MRS of pediatric posterior fossa tumors seems to be helpful in prediction of tumor grading and histology." | 1.31 | [Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors]. ( Biegański, T; Kreisel, J; Liberski, PP; Nowosławska, E; Polis, L; Zakrzewski, K, 2001) |
| "Eleven primitive neuroectodermal tumors (patient age, 2 to 12 years; mean, 7 years), 11 low-grade astrocytomas (age, 2 to 16 years; mean, 9 years), 4 ependymomas (age, 1 to 6 years; mean, 4 years), 1 mixed glioma ependymo-astrocytoma (age, 11 years), 1 anaplastic ependymoma (age, 7 years), 1 ganglioglioma (age, 14 years), and 1 malignant teratoma (age, 6 days) were studied." | 1.29 | Proton MR spectroscopy of pediatric cerebellar tumors. ( Bilaniuk, LT; Cnaan, A; Haselgrove, JC; Rorke, LB; Sutton, LN; Wang, Z; Zhao, H; Zimmerman, RA, 1995) |
| "Lonidamine (LND) has been shown to inhibit tumor aerobic glycolysis." | 1.27 | Effect of lonidamine on human malignant gliomas: biochemical studies. ( Caputo, A; Carapella, CM; Del Carlo, C; Fanciulli, M; Floridi, A; Giorno, S; Paggi, MG; Silvestrini, B; Zupi, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 12 (57.14) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McLean, MA | 2 |
| Sun, A | 1 |
| Bradstreet, TE | 1 |
| Schaeffer, AK | 1 |
| Liu, H | 2 |
| Iannone, R | 1 |
| Herman, G | 1 |
| Railkar, RA | 1 |
| Joubert, I | 1 |
| Gillard, JH | 1 |
| Price, SJ | 1 |
| Griffiths, JR | 2 |
| Howe, FA | 1 |
| Barton, SJ | 1 |
| Cudlip, SA | 1 |
| Stubbs, M | 1 |
| Saunders, DE | 1 |
| Murphy, M | 1 |
| Wilkins, P | 1 |
| Opstad, KS | 1 |
| Doyle, VL | 1 |
| Bell, BA | 1 |
| Bulakbasi, N | 1 |
| Kocaoglu, M | 1 |
| Ors, F | 1 |
| Tayfun, C | 1 |
| Uçöz, T | 1 |
| Yang, Y | 1 |
| Basu, S | 1 |
| Tomasko, DL | 1 |
| Lee, LJ | 1 |
| Yang, ST | 1 |
| Jenkinson, MD | 1 |
| Smith, TS | 1 |
| Joyce, K | 1 |
| Fildes, D | 1 |
| du Plessis, DG | 1 |
| Warnke, PC | 1 |
| Walker, C | 1 |
| Beckner, ME | 1 |
| Gobbel, GT | 1 |
| Abounader, R | 1 |
| Burovic, F | 1 |
| Agostino, NR | 1 |
| Laterra, J | 1 |
| Pollack, IF | 1 |
| Pulkkinen, J | 1 |
| Häkkinen, AM | 1 |
| Lundbom, N | 1 |
| Paetau, A | 1 |
| Kauppinen, RA | 1 |
| Hiltunen, Y | 1 |
| Lemire, J | 1 |
| Mailloux, RJ | 1 |
| Appanna, VD | 1 |
| Preul, MC | 1 |
| Caramanos, Z | 1 |
| Collins, DL | 1 |
| Villemure, JG | 1 |
| Leblanc, R | 1 |
| Olivier, A | 1 |
| Pokrupa, R | 1 |
| Arnold, DL | 1 |
| Wang, Z | 1 |
| Sutton, LN | 1 |
| Cnaan, A | 1 |
| Haselgrove, JC | 1 |
| Rorke, LB | 1 |
| Zhao, H | 1 |
| Bilaniuk, LT | 1 |
| Zimmerman, RA | 1 |
| Siderowf, AD | 1 |
| Balcer, LJ | 1 |
| Kenyon, LC | 1 |
| Nei, M | 1 |
| Raps, EC | 1 |
| Galetta, SL | 1 |
| Hwang, JH | 1 |
| Egnaczyk, GF | 1 |
| Ballard, E | 1 |
| Dunn, RS | 1 |
| Holland, SK | 1 |
| Ball, WS | 1 |
| Meyerand, ME | 1 |
| Pipas, JM | 1 |
| Mamourian, A | 1 |
| Tosteson, TD | 1 |
| Dunn, JF | 1 |
| Dezortová, M | 1 |
| Hájek, M | 1 |
| Cáp, F | 1 |
| Babis, M | 1 |
| Tichý, M | 1 |
| Vymazal, J | 1 |
| Graves, EE | 1 |
| Nelson, SJ | 1 |
| Vigneron, DB | 1 |
| Chin, C | 1 |
| Verhey, L | 1 |
| McDermott, M | 1 |
| Larson, D | 1 |
| Sneed, PK | 1 |
| Chang, S | 1 |
| Prados, MD | 1 |
| Lamborn, K | 1 |
| Dillon, WP | 1 |
| Ricci, PE | 1 |
| Pitt, A | 1 |
| Keller, PJ | 1 |
| Coons, SW | 1 |
| Heiserman, JE | 1 |
| Hall, WA | 1 |
| Martin, AJ | 1 |
| Truwit, CL | 1 |
| Ishimaru, H | 1 |
| Morikawa, M | 1 |
| Iwanaga, S | 1 |
| Kaminogo, M | 1 |
| Ochi, M | 1 |
| Hayashi, K | 1 |
| Zakrzewski, K | 1 |
| Kreisel, J | 1 |
| Polis, L | 1 |
| Nowosławska, E | 1 |
| Liberski, PP | 1 |
| Biegański, T | 1 |
| Henriksen, O | 1 |
| Wieslander, S | 1 |
| Gjerris, F | 1 |
| Jensen, KM | 1 |
| Paggi, MG | 1 |
| Carapella, CM | 1 |
| Fanciulli, M | 1 |
| Del Carlo, C | 1 |
| Giorno, S | 1 |
| Zupi, G | 1 |
| Silvestrini, B | 1 |
| Caputo, A | 1 |
| Floridi, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Development of Magnetic Resonance Spectroscopy (MRS) Biomarkers of Tumor Metabolism[NCT01138813] | 8 participants (Actual) | Observational | 2009-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Choline; Humans; Infant; Lacti | 1998 |
20 other studies available for lactic acid and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Repeatability of edited lactate and other metabolites in astrocytoma at 3T.
Topics: Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Female; Humans; Lactic Acid; Magnetic Resonance Spe | 2012 |
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi | 2003 |
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat | 2003 |
Fabrication of well-defined PLGA scaffolds using novel microembossing and carbon dioxide bonding.
Topics: Animals; Astrocytoma; Biocompatible Materials; Carbon Dioxide; Cell Adhesion; Cell Culture Technique | 2005 |
MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypes.
Topics: Adult; Aged; Allelic Imbalance; Astrocytoma; Brain Neoplasms; Choline; Chromosomes, Human, Pair 1; C | 2005 |
Glycolytic glioma cells with active glycogen synthase are sensitive to PTEN and inhibitors of PI3K and gluconeogenesis.
Topics: Astrocytoma; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen; Drug Combinations; Enzyme Inh | 2005 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio | 2005 |
Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1).
Topics: Adenosine Triphosphate; Astrocytoma; Cell Line, Tumor; Cell Respiration; Energy Metabolism; Humans; | 2008 |
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D | 1996 |
Proton MR spectroscopy of pediatric cerebellar tumors.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Chemistry; Cerebellar Neoplasms; Child; Child, Prescho | 1995 |
Central neurogenic hyperventilation in an awake patient with a pontine glioma.
Topics: Astrocytoma; Brain Neoplasms; Cerebrospinal Fluid; Humans; Hydrogen-Ion Concentration; Hyperventilat | 1996 |
Classification of biopsy-confirmed brain tumors using single-voxel MR spectroscopy.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Astrocytoma; Biopsy; Body Water; Brain Neoplasms; | 1999 |
Comparison of MR spectroscopy and MR imaging with contrast agent in children with cerebral astrocytomas.
Topics: Adolescent; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Contrast Media; Gadolinium | 1999 |
A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Aci | 2000 |
Effect of voxel position on single-voxel MR spectroscopy findings.
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glio | 2000 |
An efficient chemical shift imaging scheme for magnetic resonance-guided neurosurgery.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Biopsy; Brain; Brain Mapping; Brain Neop | 2001 |
Differentiation between high-grade glioma and metastatic brain tumor using single-voxel proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chil | 2001 |
[Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors].
Topics: Adolescent; Aspartic Acid; Astrocytoma; Child; Child, Preschool; Choline; Creatine; Diagnosis, Diffe | 2001 |
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate | 1991 |
Effect of lonidamine on human malignant gliomas: biochemical studies.
Topics: Astrocytoma; Deoxy Sugars; Deoxyglucose; Glycolysis; Hexokinase; Humans; Indazoles; Lactates; Lactic | 1988 |