Page last updated: 2024-10-17

lactic acid and Alveolitis, Fibrosing

lactic acid has been researched along with Alveolitis, Fibrosing in 10 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Pulmonary fibrosis is a chronic lung disease characterized by inflammation and collagen deposition, with an estimated mortality rate exceeding 70%."5.43Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. ( Choi, HG; Hwang, HS; Lee, C; Lee, EH; Lee, ES; Lee, S; Seo, J; Thao, LQ; Youn, YS, 2016)
"Although pulmonary dosing of large porous particles has been shown to sustain drug delivery for a few days, there are no reports on safety or long term delivery."5.39Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose. ( Dhanda, DS; Kompella, UB; Mirvish, SS; Tyagi, P, 2013)
"Pulmonary fibrosis is a chronic lung disease characterized by inflammation and collagen deposition, with an estimated mortality rate exceeding 70%."1.43Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. ( Choi, HG; Hwang, HS; Lee, C; Lee, EH; Lee, ES; Lee, S; Seo, J; Thao, LQ; Youn, YS, 2016)
"Pulmonary fibrosis is a common and dose-limiting side-effect of ionizing radiation used to treat cancers of the thoracic region."1.42Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase. ( Judge, JL; Kottmann, RM; Owens, KM; Phipps, RP; Pollock, SJ; Sime, PJ; Thatcher, TH; Williams, JP; Woeller, CF, 2015)
"Although pulmonary dosing of large porous particles has been shown to sustain drug delivery for a few days, there are no reports on safety or long term delivery."1.39Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose. ( Dhanda, DS; Kompella, UB; Mirvish, SS; Tyagi, P, 2013)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Xu, Q1
Mei, S1
Nie, F1
Zhang, Z1
Feng, J1
Zhang, J1
Qian, X1
Gao, Y2
He, Z1
Xing, S1
Dhanda, DS1
Tyagi, P1
Mirvish, SS1
Kompella, UB1
da Silva Bitencourt, C1
Gelfuso, GM1
Pereira, PA1
de Assis, PA1
Tefé-Silva, C1
Ramos, SG1
Arantes, EC1
Faccioli, LH1
Greguš, M1
Foret, F1
Kindlová, D1
Pokojová, E1
Plutinský, M1
Doubková, M1
Merta, Z1
Binková, I1
Skřičková, J1
Kubáň, P1
Judge, JL2
Owens, KM2
Pollock, SJ1
Woeller, CF1
Thatcher, TH2
Williams, JP1
Phipps, RP2
Sime, PJ2
Kottmann, RM2
Trawick, E1
Wahl, LA1
Epa, AP1
Lee, C1
Seo, J1
Hwang, HS1
Thao, LQ1
Lee, S1
Lee, ES1
Lee, EH1
Choi, HG1
Youn, YS1
Zhang, H1
Lv, W1
Jiao, C1
Duan, M1
Liu, H1
Han, B1
Bye, PT1
Anderson, SD1
Woolcock, AJ1
Young, IH1
Alison, JA1
Fireman, E1
Shahar, I1
Shoval, S1
Messer, G1
Dvash, S1
Grief, J1

Other Studies

10 other studies available for lactic acid and Alveolitis, Fibrosing

ArticleYear
The role of macrophage-fibroblast interaction in lipopolysaccharide-induced pulmonary fibrosis: an acceleration in lung fibroblast aerobic glycolysis.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:4

    Topics: Acceleration; Fibroblasts; Glycolysis; Humans; Lactic Acid; Lipopolysaccharides; Lung; Macrophages;

2022
Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Jun-28, Volume: 168, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Bron

2013
Hyaluronidase-loaded PLGA microparticles as a new strategy for the treatment of pulmonary fibrosis.
    Tissue engineering. Part A, 2015, Volume: 21, Issue:1-2

    Topics: Animals; Cattle; Cell Count; Cell Line; Collagen; Cytoskeleton; Hyaluronoglucosaminidase; Lactic Aci

2015
Monitoring the ionic content of exhaled breath condensate in various respiratory diseases by capillary electrophoresis with contactless conductivity detection.
    Journal of breath research, 2015, May-06, Volume: 9, Issue:2

    Topics: Acetates; Adult; Aged; Ammonium Compounds; Asthma; Breath Tests; Butyrates; Calcium; Chlorides; Crow

2015
Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Oct-15, Volume: 309, Issue:8

    Topics: Animals; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Gossypol; Humans; Isoenzymes; L-L

2015
Pharmacologic inhibition of lactate production prevents myofibroblast differentiation.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Dec-01, Volume: 309, Issue:11

    Topics: Animals; Cell Differentiation; Cell Line; Enzyme Inhibitors; Extracellular Matrix; Gene Knockdown Te

2015
Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 78

    Topics: Administration, Inhalation; Aerosols; Animals; Bleomycin; Chitosan; Collagen; Hydroxyproline; Imagin

2016
Preparation of bleomycin A2-PLGA microspheres and related in vitro and in vivo studies.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Chemistry, Pharmaceutical; Chromatography, Liquid;

2011
Bicycle endurance performance of patients with interstitial lung disease breathing air and oxygen.
    The American review of respiratory disease, 1982, Volume: 126, Issue:6

    Topics: Air; Exercise Test; Female; Humans; Lactates; Lactic Acid; Lung Volume Measurements; Male; Middle Ag

1982
Morphological and biochemical properties of alveolar fibroblasts in interstitial lung diseases.
    Lung, 2001, Volume: 179, Issue:2

    Topics: Adult; Aged; Bronchoalveolar Lavage Fluid; Calcium; Cell Count; Cells, Cultured; Collagen; Creatine

2001